A qualitative systematic review of suicide behavior using the cognitive systems domain of the research domain criteria (RDoC) framework
Abstract
Neurocognitive deficits are associated with both suicide behavior (SB) and psychiatric disorders. Application of a transdiagnostic framework to identify neurocognitive commonalities of SB may clarify important risk factors of SB across psychiatric disorders. The aim of this study was to conduct a qualitative systematic literature review of SB using the Research Domain Criteria (RDoC) Cognitive Systems framework to determine if cognitive deficits exist independently of psychiatric disorders in SB. The following six constructs that encompass the Cognitive Systems domain were assessed: 1) Attention, 2) Cognitive Control, 3) Declarative Memory, 4) Language, 5) Perception, and 6) Working Memory. A total of 1386 abstracts were identified and 74 studies met the inclusion criteria for this review. The majority of studies reviewed (65%) had significant differences in cognition between individuals with and without SB. Seventy-nine percent of studies with a patient control group showed significant cognitive deficits in SB groups. Deficits in cognitive control were associated with SB and had the greatest percentage of studies with significant main findings. Use of the RDoC cognitive systems framework to evaluate SB revealed that cognitive deficits may be a transdiagnostic risk factor for SB, especially alterations in cognitive control.
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Suicide attempters exhibit less language fluency and learning.
“- Suicide attempters exhibit less language fluency and learning (38) and impaired deterministic learning in the context of complex unambiguous environments (39).”
From A brain-centric model of suicidal behavior (2020) · cites this paper as [38]
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A brain-centric model of suicidal behavior
Mann, J. J., & Rizk, M. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20081224 · Cited by 214 · see citing works
- Authors
- Huber, R. S., Hodgson, R., & Yurgelun-Todd, D. A.
- Affiliations
- University of Utah (US)
- United States Department of Veterans Affairs (US)
- Corresponding author
- Huber, Rebekah S.
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2019-12
- Volume
- 282
- Pages
- 112589
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2987550696
- Cited by
- 25
- References
- 85
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 5 · 2023: 3 · 2022: 2 · 2021: 6 · 2020: 4
- FWCI
- 0.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Utah Science Technology and Research
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- suicidal behavior, cognitive impairment, cognitive control, Research Domain Criteria, transdiagnostic risk factors, attention, declarative memory, language, perception, working memory, neurocognitive impairment
- MeSH terms
- Self-Control, Attention, Cognition, Cognition Disorders, Humans, Language, Memory, Memory, Short-Term, Perception, Risk Factors, Suicidal Ideation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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