Cited by 50Suicide and Self-Harm StudiesNeural and Behavioral Psychology StudiesPsychopathy, Forensic Psychiatry, Sexual Offending

Neural substrates of suicide and suicidal behaviour: From a neuroimaging perspective

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Balcioglu, Yasin Hasan, Kose, Samet·2018·Psychiatry and Clinical Psychopharmacology

Abstract

In this article, we have reviewed neuroimaging studies on the neural circuitry associated with suicidal behaviour in order to identify the neural substrates of suicidal behaviour. The Medline and ScienceDirect databases were comprehensively and systematically searched and articles published from 1990 through 2017 were reviewed. Reviewed brain-imaging modalities included structural magnetic resonance imaging, diffusion tensor imaging, positron-emission tomography, single-photon emission computed tomography, resting-state functional Imaging, and functional magnetic resonance imaging. Although subject characteristics and imaging methods vary across studies, convergent findings involving the structure and function of frontostriatal network and fronto-limbic structures, and the serotonergic system were identified. These neuroimaging studies of suicide behaviour have provided crucial information on the neural circuitry associated with suicide risk. Future studies examining neural changes associated with before and after pharmacologic and behavioural interventions would be instrumental in suicide risk reduction.

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Crossref · 10.1080/24750573.2017.1420378

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  1. [2][2] Hawton K, van Heeringen K. Suicide. The Lancet. 2009;373:1372 -1381. -

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Authors
Balcioglu, Y. H., & Kose, S.
Affiliations
  • Neurology, and Neurosurgery, Forensic Psychiatry Unit, Bakirkoy Prof. Mazhar Osman Training and Research Hospital for Psychiatry, Istanbul, Turkey
  • Department of Psychology, Hasan Kalyoncu University, Gaziantep, Turkey
Venue
Psychiatry and Clinical Psychopharmacology
Published
2018-01-03
Volume
28
Issue
3
Pages
314-328
ISSN
  • 2475-0573 (ISSN-L)
  • 2475-0581
OpenAlex
W2781678342
Cited by
50
References
115
Citations by year
2026: 7 · 2025: 3 · 2024: 5 · 2023: 4 · 2022: 5 · 2021: 11 · 2020: 7 · 2019: 5 · 2018: 3
FWCI
7.60
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Psychiatry and Clinical Psychopharmacology (publishedVersion, cc-by)
  • Psychiatry and Clinical Psychopharmacology (publishedVersion, cc-by-nc)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Hasan Kalyoncu University Institutional Repository (Hasan Kalyoncu University) (submittedVersion, cc-by-nc-nd)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Keywords
suicide, suicidal behavior, neural correlates, neural circuits, fronto-striatal network, serotonergic system, suicide risk, suicide risk reduction

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