Angiogenesis in the atherosclerotic plaque

Camaré, Caroline; Pucelle, Mélanie; Nègre-Salvayre, Anne; Salvayre, Robert

doi:10.1016/j.redox.2017.01.007

Cited by 401Atherosclerosis and Cardiovascular DiseasesAngiogenesis and VEGF in CancerCerebrovascular and Carotid Artery Diseases

Angiogenesis in the atherosclerotic plaque

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Camaré, Caroline, Pucelle, Mélanie, Nègre-Salvayre, Anne, Salvayre, Robert·2017·Redox Biology

DOI 10.1016/j.redox.2017.01.007PMC PMC5312547

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Abstract

Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries characterized by a local accumulation of cholesterol and non-resolving inflammation. Atherothrombotic complications are the leading cause of disability and mortality in western countries. Neovascularization in atherosclerotic lesions plays a major role in plaque growth and instability. The angiogenic process is mediated by classical angiogenic factors and by additional factors specific to atherosclerotic angiogenesis. In addition to its role in plaque progression, neovascularization may take part in plaque destabilization and thromboembolic events. Anti-angiogenic agents are effective to reduce atherosclerosis progression in various animal models. However, clinical trials with anti-angiogenic drugs, mainly anti-VEGF/VEGFR, used in anti-cancer therapy show cardiovascular adverse effects, and require additional investigations.

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Interaction between ECM on the surface of endothelial cells and integrins can initiate the intracellular PI3K-AKT-eNOS signaling pathway, leading to the production of NO.
“It is well-documented that the interaction between the ECM on the surface of endothelial cells and integrins can initiate the intracellular PI3K-AKT-eNOS signaling pathway, leading to the production of NO.”
From Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models (2025) · cites this paper as [48]
The NO/NOS discussion under “Classical factors involved in angiogenesis” (page not provided) says PI3K/Akt regulates endothelial eNOS and that eNOS generates NO. It does not say that ECM–integrin interactions initiate this pathway; the paper’s integrin discussion concerns targeted drug delivery instead. (LLM, conf=0.88)
Experimental — accuracy not yet measured
This enhancement is likely due to the activation of eNOS following the inoculation of endothelial cells onto the scaffold and their subsequent contact with the ECM, initiating a series of reactions that result in increased NO secretion.
“This enhancement is likely due to the activation of eNOS following the inoculation of endothelial cells onto the scaffold and their subsequent contact with the ECM, initiating a series of reactions that result in increased NO secretion [47,48].”
From Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models (2025) · cites this paper as [48]
The ‘Classical factors involved in angiogenesis’ section states that endothelial eNOS produces NO and that extracellular stimuli can regulate eNOS activity. It does not say that inoculating endothelial cells onto a scaffold or their contact with the ECM activates eNOS and increases NO secretion. (LLM, conf=0.85)
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Atherosclerosis--an inflammatory disease
Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725 · see citing works
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
Furchgott, R. F., & Zawadzki, J. V. (1980) · Nature · doi:10.1038/288373a0 · Cited by 12,064 · see citing works
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704 · see citing works
The pathogenesis of atherosclerosis: a perspective for the 1990s
Ross, R. (1993) · Nature · doi:10.1038/362801a0 · Cited by 10,618 · see citing works
The biology of VEGF and its receptors
Ferrara, N., Gerber, H.-P., & LeCouter, J. (2003) · Nature Medicine · doi:10.1038/nm0603-669 · Cited by 9,591 · see citing works
Inflammation in atherosclerosis
Libby, P. (2002) · Nature · doi:10.1038/nature01323 · Cited by 8,315 · see citing works
Beyond Cholesterol
Epstein, F. H., Steinberg, D. I., Parthasarathy, S., Carew, T. E., Khoo, J. C., & Witztum, J. L. (1989) · New England Journal of Medicine · doi:10.1056/nejm198904063201407 · Cited by 6,425 · see citing works
Molecular mechanisms and clinical applications of angiogenesis
Carmeliet, P., & Jain, R. K. (2011) · Nature · doi:10.1038/nature10144 · Cited by 5,467 · see citing works
Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
Cillà, S. D., Farruggio, S., Vujosevic, S., Raina, G., Filippini, D. A., Gatti, V., Clemente, N., Mary, D., Vezzola, D., Casini, G., et al. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479441 · Cited by 5,153 · see citing works
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.
Ignarro, L. J., Buga, G. M., Wood, K. S., Byrns, R. E., & Chaudhuri, G. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9265 · Cited by 5,074 · see citing works
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
Leung, D. W., Cachianes, G., Kuang, W.-J., Goeddel, D. V., & Ferrara, N. (1989) · Science · doi:10.1126/science.2479986 · Cited by 4,988 · see citing works
Atherosclerosis
Lusis, A. J. (2000) · Nature · doi:10.1038/35025203 · Cited by 4,880 · see citing works
Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients
Locatelli, F., Fishbane, S. N., Block, G. A., & Macdougall, I. C. (2017) · American Journal of Nephrology · doi:10.1159/000455166 · Cited by 4,834 · see citing works
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
Shweiki, D., Itin, A., Soffer, D., & Keshet, E. (1992) · Nature · doi:10.1038/359843a0 · Cited by 4,617 · see citing works
Nitric oxide synthases: regulation and function
Forstermann, U., & Sessa, W. C. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr304 · Cited by 4,409 · see citing works
Angiogenesis in health and disease
Carmeliet, P. (2003) · Nature Medicine · doi:10.1038/nm0603-653 · Cited by 4,258 · see citing works
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., et al. (1996) · Nature · doi:10.1038/380435a0 · Cited by 4,114 · see citing works
Nitric oxide synthases: structure, function and inhibition
ALDERTON, W. K., Cooper, C. E., & Knowles, R. G. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3570593 · Cited by 4,106 · see citing works
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature · doi:10.1038/nature08938 · Cited by 4,026 · see citing works
Progress and challenges in translating the biology of atherosclerosis
Libby, P., Ridker, P. M., & Hansson, G. K. (2011) · Nature · doi:10.1038/nature10146 · Cited by 4,010 · see citing works
Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid
Senger, D. R., Galli, S. J., Dvořàk, A. M., Perruzzi, C. A., Harvey, V. S., & Dvorak, H. F. (1983) · Science · doi:10.1126/science.6823562 · Cited by 3,969 · see citing works
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X.-F., Breitman, M. L., & Schuh, A. C. (1995) · Nature · doi:10.1038/376062a0 · Cited by 3,931 · see citing works
Inflammation in Atherosclerosis
Libby, P. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.179705 · Cited by 3,748 · see citing works
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
Ferrara, N. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0027 · Cited by 3,707 · see citing works
Vascular-specific growth factors and blood vessel formation
Yancopoulos, G. D., Davis, S., Gale, N. W., Rudge, J. S., Wiegand, S. J., & Holash, J. (2000) · Nature · doi:10.1038/35025215 · Cited by 3,699 · see citing works
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., O’Shea, K. S., Powell-Braxton, L., Hillan, K. J., & Moore, M. W. (1996) · Nature · doi:10.1038/380439a0 · Cited by 3,624 · see citing works
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
Maisonpierre, P. C., Suri, C., Jones, P. F., Bartunkova, S., Wiegand, S. J., Radziejewski, C., Compton, D., McClain, J., Aldrich, T. H., Papadopoulos, N., et al. (1997) · Science · doi:10.1126/science.277.5322.55 · Cited by 3,570 · see citing works
A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis
Stary, H. C., Chandler, A. B., Dinsmore, R. E., Fuster, V., Glagov, S. K., Insull, W., Rosenfeld, M. E., Schwartz, C. J., Wagner, W. D., & Wissler, R. W. (1995) · Circulation · doi:10.1161/01.cir.92.5.1355 · Cited by 3,506 · see citing works
Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis
Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S. H., Sato, T. N., & Yancopoulos, G. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81813-9 · Cited by 2,831 · see citing works
Basic and Therapeutic Aspects of Angiogenesis
Potente, M., Gerhardt, H., & Carmeliet, P. (2011) · Cell · doi:10.1016/j.cell.2011.08.039 · Cited by 2,771 · see citing works
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor.
Soker, S., Takashima, S., Miao, H., Neufeld, G., & Klagsbrun, M. (1998) · Cell · doi:10.1016/s0092-8674(00)81402-6 · Cited by 2,634 · see citing works
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
Semenza, G. L., & Wang, G. L. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.12.5447 · Cited by 2,617 · see citing works
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
Fulton, D. J., Gratton, J., McCabe, T. J. D., Fontana, J. T., Fujio, Y., Walsh, K., Franke, T. F., Papapetropoulos, A., & Sessa, W. C. (1999) · Nature · doi:10.1038/21218 · Cited by 2,612 · see citing works
Role of Oxidative Modifications in Atherosclerosis
Stocker, R., & Keaney, J. F. (2004) · Physiological Reviews · doi:10.1152/physrev.00047.2003 · Cited by 2,611 · see citing works
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
Fong, G.-H., Rossant, J., Gertsenstein, M., & Breitman, M. L. (1995) · Nature · doi:10.1038/376066a0 · Cited by 2,606 · see citing works
Regulation of angiogenesis by hypoxia: role of the HIF system
Pugh, C. W., & Ratcliffe, P. J. (2003) · Nature Medicine · doi:10.1038/nm0603-677 · Cited by 2,520 · see citing works
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
Lindahl, P., Johansson, B. R., Levéen, P., & Betsholtz, C. (1997) · Science · doi:10.1126/science.277.5323.242 · Cited by 2,226 · see citing works
Regulation of hypoxia-inducible factor 1α is mediated by an O 2 -dependent degradation domain via the ubiquitin-proteasome pathway
Huang, L. E., Gu, J., Schau, M., & Bunn, H. F. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.14.7987 · Cited by 2,113 · see citing works
Sphingosine-1-phosphate: an enigmatic signalling lipid
Spiegel, S., & Milstien, S. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1103 · Cited by 2,080 · see citing works
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
Huang, P. L., Huang, Z., Mashimo, H., Bloch, K. D., Moskowitz, M. A., Bevan, J. A., & Fishman, M. C. (1995) · Nature · doi:10.1038/377239a0 · Cited by 2,070 · see citing works
Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF
Keck, P. J., Hauser, S. D., Krivi, G. G., Sanzo, K., Warren, T. G., Feder, J., & Connolly, D. T. (1989) · Science · doi:10.1126/science.2479987 · Cited by 2,058 · see citing works
The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor
de Vries, C. J. M., Escobedo, J. A., Ueno, H., Houck, K. A., Ferrara, N., & Williams, L. T. (1992) · Science · doi:10.1126/science.1312256 · Cited by 2,019 · see citing works
Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning
Davis, S., Aldrich, T. H., Jones, P. F., Acheson, A., Compton, D. L., Jain, V., Ryan, T. E., Bruno, J., Radziejewski, C., Maisonpierre, P. C., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81812-7 · Cited by 1,989 · see citing works
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
Tischer, E., Mitchell, R., Hartman, T., Silva, M., Gospodarowicz, D., Fiddes, J. C., & Abraham, J. A. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99049-6 · Cited by 1,972 · see citing works
Vascular Endothelial Growth Factor and Angiogenesis
Hoeben, A., Landuyt, B., Highley, M. S., Wildiers, H., Van Oosterom, A. T., & De Bruijn, E. A. (2004) · Pharmacological Reviews · doi:10.1124/pr.56.4.3 · Cited by 1,824 · see citing works
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
Sato, T. N., Tozawa, Y., Deutsch, U., Wolburg‐Buchholz, K., Fujiwara, Y., Gendron‐Maguire, M., Gridley, T., Wolburg, H., Risau, W., & Qin, Y. (1995) · Nature · doi:10.1038/376070a0 · Cited by 1,821 · see citing works
Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
Hellström, M., Kalén, M., Lindahl, P., Abramsson, A., & Betsholtz, C. (1999) · Development · doi:10.1242/dev.126.14.3047 · Cited by 1,702 · see citing works
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
Carmeliet, P., Moons, L., Luttun, A., Vincenti, V., Compernolle, V., Mol, M. D., Wu, Y., Bono, F., Devy, L., Beck, H., et al. (2001) · Nature Medicine · doi:10.1038/87904 · Cited by 1,673 · see citing works
Isolation of a tumor factor responsible for angiogenesis
Folkman, J., Merler, E., Abernathy, C., & Williams, G. (1971) · The Journal of Experimental Medicine · doi:10.1084/jem.133.2.275 · Cited by 1,663 · see citing works
Signal Transduction by Vascular Endothelial Growth Factor Receptors
Koch, S., Tugues, S., Li, X., Gualandi, L., & Claesson, L. (2011) · Biochemical Journal · doi:10.1042/bj20110301 · Cited by 1,628 · see citing works
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
Terman, B. I., Dougher-Vermazen, M., Carrion, M. E., Dimitrov, D. S., Armellino, D. C., Gospodarowicz, D., & Böhlen, P. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(92)90483-2 · Cited by 1,519 · see citing works
Mechanisms and regulation of endothelial VEGF receptor signalling
Simons, M., Gordon, E., & Claesson-Welsh, L. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.87 · Cited by 1,498 · see citing works
Intraplaque Hemorrhage and Progression of Coronary Atheroma
Kolodgie, F. D., Gold, H. K., BURKE, A. P., Fowler, D. R., Kruth, H. S., Weber, D. K., Farb, A. A., Guerrero, L. J., Hayase, M., Kutys, R., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa035655 · Cited by 1,491 · see citing works
Cholesterol, inflammation and innate immunity.
Tall, A. R., & Yvan-Charvet, L. (2015) · Nature Reviews Immunology · doi:10.1038/nri3793 · Cited by 1,479 · see citing works
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
Augustin, H. G., Koh, G. Y., Thurston, G., & Alitalo, K. K. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2639 · Cited by 1,460 · see citing works
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
MacMicking, J. D., Nathan, C., Hom, G. J., Chartrain, N. A., Fletcher, D. S., Trumbauer, M. E., Stevens, K. A., Xie, Q. W., Sokol, K. A., Hutchinson, N. I., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90085-3 · Cited by 1,445 · see citing works
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
Karkkainen, M. J., Haiko, P., Sainio, K., Partanen, J. M., Taipale, J., Petrova, T. V., Jeltsch, M., Jackson, D. G., Talikka, M., Rauvala, H., et al. (2003) · Nature Immunology · doi:10.1038/ni1013 · Cited by 1,419 · see citing works
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
Barleon, B., Sozzani, S., Zhou, D., Weich, H., Mantovani, A., & Marmé, D. (1996) · Blood · doi:10.1182/blood.v87.8.3336.bloodjournal8783336 · Cited by 1,350 · see citing works
PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties
Bouhlel, M. A., Derudas, B., Rigamonti, E., Dièvart, R., Brozek, J., Haulon, S., Zawadzki, C., Jude, B., Torpier, G., Marx, N., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.06.010 · Cited by 1,325 · see citing works
Targeted disruption of the neuronal nitric oxide synthase gene
Huang, P. L., Dawson, T. M., Bredt, D. S., Snyder, S. H., & Fishman, M. C. (1993) · Cell · doi:10.1016/0092-8674(93)90615-w · Cited by 1,303 · see citing works
Altered immune responses in mice lacking inducible nitric oxide synthase
Wei, X., Charles, I. G., Smith, A. G., Ure, J. M., Feng, G.-J., Huang, F.-P., Xu, D., Müller, W., Moncada, S., & Liew, F. Y. (1995) · Nature · doi:10.1038/375408a0 · Cited by 1,292 · see citing works
Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice
Jeltsch, M., Kaipainen, A., Joukov, V., Meng, X., Lakso, M., Rauvala, H., Swartz, M. A., Fukumura, D., Jain, R. K., & Alitalo, K. K. (1997) · Science · doi:10.1126/science.276.5317.1423 · Cited by 1,279 · see citing works
Role of oxidative stress in atherosclerosis
Harrison, D., Griendling, K. K., Landmesser, U., Hornig, B., & Drexler, H. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)03144-2 · Cited by 1,275 · see citing works
A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins
Goldstein, J. L., & Brown, M. S. (2015) · Cell · doi:10.1016/j.cell.2015.01.036 · Cited by 1,233 · see citing works
Signaling Vascular Morphogenesis and Maintenance
Hanahan, D. (1997) · Science · doi:10.1126/science.277.5322.48 · Cited by 1,205 · see citing works
Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities
Razani, B., Engelman, J. A., Wang, X., Schubert, W., Zhang, X. L., Marks, C. B., Macaluso, F., Russell, R. G., Li, M., Pestell, R. G., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105408200 · Cited by 1,163 · see citing works
Cellular adaptation to hypoxia: O 2 ‐sensing protein hydroxylases, hypoxia‐inducible transcription factors, and O 2 ‐regulated gene expression
Wenger, R. H. (2002) · The FASEB Journal · doi:10.1096/fj.01-0944rev · Cited by 1,135 · see citing works
Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.Preprint
Levéen, P., Pekny, M., Gebré‐Medhin, S., Swolin, B., Larsson, E., & Betsholtz, C. (1994) · Genes & Development · doi:10.1101/gad.8.16.1875 · Cited by 1,130 · see citing works
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
Hiratsuka, S., Minowa, O., Kuno, J., Noda, T., & Shibuya, M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9349 · Cited by 1,063 · see citing works
Sphingosine-1-phosphate signaling and its role in disease
Maceyka, M., Harikumar, K. B., Milstien, S., & Spiegel, S. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.09.003 · Cited by 1,039 · see citing works
Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
Rajamäki, K., Lappalainen, J., Öörni, K., Välimäki, E., Matikainen, S., Kovanen, P. T., & Eklund, K. K. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011765 · Cited by 1,039 · see citing works
Integration of Oxygen Signaling at the Consensus HRE
Wenger, R. H., Stiehl, D. P., & Camenisch, G. (2005) · Science's STKE · doi:10.1126/stke.3062005re12 · Cited by 1,032 · see citing works
Molecular mechanisms of blood vessel growth
Conway, E. (2001) · Cardiovascular Research · doi:10.1016/s0008-6363(00)00281-9 · Cited by 1,030 · see citing works
Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1
Gale, N. W., Thurston, G., Hackett, S. F., Renard, R. A., Wang, Q., McClain, J., Martin, C., Witte, C. L., Witte, M. H., Jackson, D. G., et al. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00217-4 · Cited by 1,017 · see citing works
Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.
Maglione, D., Guerriero, V., Viglietto, G., Bovi, P. D., & Persico, M. G. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.20.9267 · Cited by 998 · see citing works
Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.Preprint
Soriano, P. M. (1994) · Genes & Development · doi:10.1101/gad.8.16.1888 · Cited by 988 · see citing works
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.
Dumont, D. J., Gradwohl, G., Fong, G. H., Puri, M. C., Gertsenstein, M., Auerbach, A., & Breitman, M. L. (1994) · Genes & Development · doi:10.1101/gad.8.16.1897 · Cited by 985 · see citing works
Cholesterol Efflux and Atheroprotection: Advancing the Concept of Reverse Cholesterol Transport
Rosenson, R. S., Brewer, H. B., Davidson, W. S., Fayad, Z. A., Fuster, V., Goldstein, J., Hellerstein, M., Jiang, X.-C., Phillips, M. C., Rader, D. J., et al. (2012) · Circulation · doi:10.1161/circulationaha.111.066589 · Cited by 953 · see citing works
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
Takahashi, H., & Shibuya, M. (2005) · Clinical Science · doi:10.1042/cs20040370 · Cited by 950 · see citing works
The lamellipodium: where motility begins
Small, J. V., Stradal, T. E. B., Vignal, E., & Rottner, K. (2002) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02237-1 · Cited by 924 · see citing works
Hydroxylation of HIF-1: Oxygen Sensing at the Molecular Level
Semenza, G. L. (2004) · Physiology · doi:10.1152/physiol.00001.2004 · Cited by 901 · see citing works
Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3
Dumont, D., Jussila, L., Taipale, J., Lymboussaki, A., Mustonen, T., Pajusola, K., Breitman, M. L., & Alitalo, K. K. (1998) · Science · doi:10.1126/science.282.5390.946 · Cited by 873 · see citing works
Increased Vascularization in Mice Overexpressing Angiopoietin-1
Suri, C., McClain, J., Thurston, G., McDonald, D. M., Zhou, H., Oldmixon, E. H., Sato, T. N., & Yancopoulos, G. D. (1998) · Science · doi:10.1126/science.282.5388.468 · Cited by 818 · see citing works
The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
Suchting, S., Freitas, C., le Noble, F. A. C., Benedito, R., Bréant, C., Duarte, A., & Eichmann, A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611177104 · Cited by 812 · see citing works
Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases
Shibuya, M. (2012) · The Journal of Biochemistry · doi:10.1093/jb/mvs136 · Cited by 797 · see citing works
Vascular endothelial growth factor B, a novel growth factor for endothelial cells.
Olofsson, B., Pajusola, K., Kaipainen, A., von Euler, G., Joukov, V., Saksela, O., Orpana, A., Pettersson, R. F., Alitalo, K. K., & Eriksson, U. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.6.2576 · Cited by 796 · see citing works
PDGF, TGF-β, and Heterotypic Cell–Cell Interactions Mediate Endothelial Cell–induced Recruitment of 10T1/2 Cells and Their Differentiation to a Smooth Muscle Fate
Hirschi, K. K., Rohovsky, S. A., & D'Amore, P. A. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.3.805 · Cited by 796 · see citing works
Proteolytic processing regulates receptor specificity and activity of VEGF‐C
Joukov, V., Sorsa, T., Kumar, V., Jeltsch, M., Claesson, L., Cao, Y., Saksela, O., Kalkkinen, N., & Alitalo, K. K. (1997) · The EMBO Journal · doi:10.1093/emboj/16.13.3898 · Cited by 775 · see citing works
Vascular Endothelial Growth Factor Expression of Intercellular Adhesion Molecule 1 (ICAM-1), Vascular Cell Adhesion Molecule 1 (VCAM-1), and E-selectin through Nuclear Factor-κB Activation in Endothelial Cells
Kim, I., Moon, S.-O., Kim, S. H., Kim, H. J., Koh, Y. S., & Koh, G. Y. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009705200 · Cited by 761 · see citing works
Structural Identification by Mass Spectrometry of Oxidized Phospholipids in Minimally Oxidized Low Density Lipoprotein That Induce Monocyte/Endothelial Interactions and Evidence for Their Presence in Vivo
Watson, A. D., Leitinger, N., Navab, M., Faull, K. F., Hörkkö, S., Witztum, J. L., Palinski, W., Schwenke, D., Salomon, R. G., Sha, W., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.21.13597 · Cited by 753 · see citing works
Regulation of hypoxia-inducible factor-1α by NF-κB
van Uden, P., Kenneth, N. S., & Rocha, S. (2008) · Biochemical Journal · doi:10.1042/bj20080476 · Cited by 729 · see citing works
Transforming growth factor-beta: Vasculogenesis, angiogenesis, and vessel wall integrity
Pepper, M. S. (1997) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(96)00048-2 · Cited by 724 · see citing works
Oxidative stress in angiogenesis and vascular disease
Kim, Y.-W., & Byzova, T. V. (2013) · Blood · doi:10.1182/blood-2013-09-512749 · Cited by 709 · see citing works
Vascular endothelial growth factor enhances atherosclerotic plaque progression
Celletti, F. L., Waugh, J. M., Amabile, P. G., Brendolan, A., Hilfiker, P. R., & Dake, M. D. (2001) · Nature Medicine · doi:10.1038/86490 · Cited by 708 · see citing works
Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes
Sugiyama, S., Okada, Y., Sukhova, G. K., Virmani, R., Heinecke, J. W., & Libby, P. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64036-9 · Cited by 699 · see citing works
Angiogenesis Inhibitors Endostatin or TNP-470 Reduce Intimal Neovascularization and Plaque Growth in Apolipoprotein E–Deficient Mice
Moulton, K. S., Heller, E., Konerding, M. A., Flynn, E., Palinski, W., & Folkman, J. (1999) · Circulation · doi:10.1161/01.cir.99.13.1726 · Cited by 688 · see citing works
The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease.
Holmes, D. I. R., & Zachary, I. C. (2005) · Genome biology · doi:10.1186/gb-2005-6-2-209 · Cited by 662 · see citing works
Fatty acid carbon is essential for dNTP synthesis in endothelial cells
Schoors, S., Bruning, U., Missiaen, R., Queiroz, K. C. S., Borgers, G., Elia, I., Zecchin, A., Cantelmo, A. R., Christen, S., Goveia, J., et al. (2015) · Nature · doi:10.1038/nature14362 · Cited by 646 · see citing works
Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
Negre‐Salvayre, A., Coatrieux, C., Ingueneau, C., & Salvayre, R. (2008) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707395 · Cited by 641 · see citing works
Self-citation
The Pathology of Atherosclerosis: Plaque Development and Plaque Responses to Medical Treatment
Insull, W. (2008) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.10.013 · Cited by 637 · see citing works
Accelerated Atherosclerosis, Aortic Aneurysm Formation, and Ischemic Heart Disease in Apolipoprotein E/Endothelial Nitric Oxide Synthase Double-Knockout Mice
Kuhlencordt, P. J., Gyurko, R., Han, F., Scherrer‐Crosbie, M., Aretz, T. H., Hajjar, R. J., Picard, M. H., & Huang, P. L. (2001) · Circulation · doi:10.1161/hc2901.091399 · Cited by 631 · see citing works
VEGF and Notch in Tip and Stalk Cell SelectionPreprint
Blanco, R. E., & Gerhardt, H. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006569 · Cited by 622 · see citing works
Endothelial Cell Metabolism in Normal and Diseased Vasculature
Eelen, G., de Zeeuw, P., Simons, M., & Carmeliet, P. (2015) · Circulation Research · doi:10.1161/circresaha.116.302855 · Cited by 619 · see citing works
Role of reactive aldehyde in cardiovascular diseases
Uchida, K. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00226-4 · Cited by 606 · see citing works
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
Laubach, V. E., Shesely, E. G., Smithies, O., & Sherman, P. A. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.23.10688 · Cited by 580 · see citing works
Pathophysiology of native coronary, vein graft, and in-stent atherosclerosis
Yahagi, K., Kolodgie, F. D., Otsuka, F., Finn, A. V., Davis, H. R., Joner, M., & Virmani, R. (2016) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.164 · Cited by 548 · see citing works
Biochemical structural and functional properties of oxidized low-density lipoprotein
Esterbauer, H., Dieber‐Rotheneder, M., Waeg, G., Striegl, G., & Juergens, G. (1990) · Chemical Research in Toxicology · doi:10.1021/tx00014a001 · Cited by 534 · see citing works
Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy
Proia, R. L., & Hla, T. (2015) · Journal of Clinical Investigation · doi:10.1172/jci76369 · Cited by 528 · see citing works
Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease
van der Veen, B. S., de Winther, M. P. J., & Heeringa, P. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2538 · Cited by 522 · see citing works
The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.
Puri, M. C., Rossant, J., Alitalo, K. K., Bernstein, A., & Partanen, J. M. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb00276.x · Cited by 518 · see citing works
VEGF-A splicing: the key to anti-angiogenic therapeutics?
Harper, S. J., & Bates, D. O. (2008) · Nature reviews. Cancer · doi:10.1038/nrc2505 · Cited by 515 · see citing works
Vascular endothelial growth factor B controls endothelial fatty acid uptake
Hagberg, C. E., Falkevall, A., Wang, X., Larsson, E., Huusko, J., Nilsson, I., van Meeteren, L. A., Samén, E., Lu, L., Vanwildemeersch, M., et al. (2010) · Nature · doi:10.1038/nature08945 · Cited by 514 · see citing works
Regulation of Signal Transduction by Reactive Oxygen Species in the Cardiovascular System
Brown, D., & Griendling, K. K. (2015) · Circulation Research · doi:10.1161/circresaha.116.303584 · Cited by 498 · see citing works
Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT‐20 cells.
Plouët, J., Schilling, J., & Gospodarowicz, D. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08557.x · Cited by 495 · see citing works
Neovascularization in Human Atherosclerosis
Moreno, P., Purushothaman, K., Sirol, M., Levy, A. P., & Fuster, V. (2006) · Circulation · doi:10.1161/circulationaha.105.578955 · Cited by 494 · see citing works
NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes
Infante, R. E., Wang, M. L., Radhakrishnan, A., Kwon, H. J., Brown, M. S., & Goldstein, J. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807328105 · Cited by 485 · see citing works
Regulation of angiogenesis by hypoxia-inducible factor 1
Hirota, K., & Semenza, G. L. (2006) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2005.12.003 · Cited by 466 · see citing works
Pathological aspects of lipid peroxidation
Nègre‐Salvayre, A., Augè, N., Ayala, V., Başağa, H., Boada, J., Brenke, R., Chapple, S. J., Cohen, G., Fehér, J., Grune, T., et al. (2010) · Free Radical Research · doi:10.3109/10715762.2010.498478 · Cited by 451 · see citing works
Self-citation
Vascular Endothelial Growth Factor (VEGF) Expression in Human Coronary Atherosclerotic Lesions
Inoue, M., Itoh, H., Ueda, M., Naruko, T., Kojima, A., Komatsu, R., Doi, K., Ogawa, Y., Tamura, N., Takaya, K., et al. (1998) · Circulation · doi:10.1161/01.cir.98.20.2108 · Cited by 449 · see citing works
Role of Angiogenesis in Cardiovascular Disease
Khurana, R., Simons, M., Martin, J. F., & Zachary, I. C. (2005) · Circulation · doi:10.1161/circulationaha.105.535294 · Cited by 445 · see citing works
Transcriptional regulation of the Vascular Endothelial Growth Factor gene?a concert of activating factors
Pagès, G., & Pouysségur, J. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.09.032 · Cited by 443 · see citing works
Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis
Shibuya, M. (2006) · Angiogenesis · doi:10.1007/s10456-006-9055-8 · Cited by 437 · see citing works
Risk of Arterial Thromboembolic Events With Sunitinib and Sorafenib: A Systematic Review and Meta-Analysis of Clinical Trials
Choueiri, T. K., Schutz, F. A. B., Je, Y., Rosenberg, J. E., & Joaquim Bellmunt, B. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.27.2757 · Cited by 432 · see citing works
The discovery of placenta growth factor and its biological activity
De Falco, S. (2012) · Experimental and Molecular Medicine · doi:10.3858/emm.2012.44.1.025 · Cited by 425 · see citing works
NADPH Oxidase-Dependent Signaling in Endothelial Cells: Role in Physiology and Pathophysiology
Frey, R. S., Ushio‐Fukai, M., & Malik, A. B. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2008.2220 · Cited by 423 · see citing works
Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead
van Hinsbergh, V. W. M., & Koolwijk, P. (2007) · Cardiovascular Research · doi:10.1093/cvr/cvm102 · Cited by 422 · see citing works
The Sphingosine-1-phosphate Receptors S1P1, S1P2, and S1P3 Function Coordinately during Embryonic Angiogenesis
Kono, M., Mi, Y., Liu, Y., Sasaki, T., Allende, M. L., Wu, Y., Yamashita, T., & Proia, R. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403937200 · Cited by 415 · see citing works
tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.
Dumont, D., Yamaguchi, T. P., Conlon, R. A., Rossant, J., & Breitman, M. L. (1992) · PubMed · Cited by 410 · see citing works
Angiogenesis
Simons, M. (2005) · Circulation · doi:10.1161/01.cir.0000159345.00591.8f · Cited by 410 · see citing works
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells
Mitra, P., Oskeritzian, C. A., Payne, S. G., Beaven, M. A., Milstien, S., & Spiegel, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603734103 · Cited by 407 · see citing works
Signaling by members of the TGF-β family in vascular morphogenesis and disease
Pardali, E., Goumans, M., & ten Dijke, P. (2010) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.06.006 · Cited by 402 · see citing works
Mechanisms of Vessel Branching
Smet, F. D., Segura, I., Bock, K. D., Hohensinner, P. J., & Carmeliet, P. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.185165 · Cited by 398 · see citing works
Thirty Years of Saying NO
Vanhoutte, P. M., Zhao, Y., Xu, A., & Leung, S. W. S. (2016) · Circulation Research · doi:10.1161/circresaha.116.306531 · Cited by 391 · see citing works
Endothelial α ν β 3 Integrin–Targeted Fumagillin Nanoparticles Inhibit Angiogenesis in Atherosclerosis
Winter, P. M., Neubauer, A. M., Caruthers, S. D., Harris, T. D., Robertson, J. D., Williams, T. A., Schmieder, A. H., Hu, G., Allen, J. S., Lacy, E. K., et al. (2006) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000235724.11299.76 · Cited by 379 · see citing works
Intraplaque haemorrhages as the trigger of plaque vulnerability
Michel, J., Virmani, R., Arbustini, E., & Pasterkamp, G. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr054 · Cited by 379 · see citing works
A Novel Endothelial Cell Surface Receptor Tyrosine Kinase with Extracellular Epidermal Growth Factor Homology Domains
Partanen, J. M., Armstrong, E., Mäkelä, T. P., Korhonen, J., Sandberg, M., Renkonen, R., Knuutila, S., Huebner, K., & Alitalo, K. K. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.4.1698 · Cited by 373 · see citing works
Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis
Sluimer, J. C., & Daemen, M. J. A. P. (2009) · The Journal of Pathology · doi:10.1002/path.2518 · Cited by 368 · see citing works
Persico MG.Isolation of a human placenta cDNA coding for a potein related to the vascular premeability factor
Maglione, D. (1991) · Medical Entomology and Zoology · Cited by 352 · see citing works
Angiogenesis and the atherosclerotic carotid plaque: An association between symptomatology and plaque morphology
McCarthy, M. J., Loftus, I. M., THOMPSON, M. M., Jones, L., London, N. J. M., Bell, P. R. F., Naylor, A. R., & Brindle, N. P. J. (1999) · Journal of Vascular Surgery · doi:10.1016/s0741-5214(99)70136-9 · Cited by 351 · see citing works
Transforming growth factor-beta 1 (tgf-β1) induces angiogenesis through vascular endothelial growth factor (vegf)-mediated apoptosis
Ferrari, G. M., Ferrari, G., Cook, B., Terushkin, V., Pintucci, G., & Mignatti, P. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21706 · Cited by 340 · see citing works
Extracellular matrix, inflammation, and the angiogenic response
Arroyo, A. G., & Iruela‐Arispe, M. L. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq049 · Cited by 336 · see citing works
Mice Lacking the Vascular Endothelial Growth Factor-B Gene ( Vegfb ) Have Smaller Hearts, Dysfunctional Coronary Vasculature, and Impaired Recovery From Cardiac Ischemia
Bellomo, D., Headrick, J. P., Silins, G. U., Paterson, C. A., Thomas, P. S., Gartside, M. G., Mould, A. W., Cahill, M. M., Tonks, I. D., Grimmond, S. M., et al. (2000) · Circulation Research · doi:10.1161/01.res.86.2.e29 · Cited by 333 · see citing works
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice
Martel, C., Li, W., Fulp, B. E., Platt, A. M., Gautier, E. L., Westerterp, M., Bittman, R., Tall, A. R., Chen, S., Thomas, M. J., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci63685 · Cited by 332 · see citing works
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
Fukuhara, S., Simmons, S., Kawamura, S., Inoue, A., Orba, Y., Tokudome, T., Sunden, Y., Arai, Y., Moriwaki, K., Ishida, J., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci60746 · Cited by 328 · see citing works
Lymphatic System in Cardiovascular Medicine
Aspelund, A., Robciuc, M. R., Karaman, S., Mäkinen, T., & Alitalo, K. K. (2016) · Circulation Research · doi:10.1161/circresaha.115.306544 · Cited by 321 · see citing works
Coronary Intraplaque Hemorrhage Evokes a Novel Atheroprotective Macrophage Phenotype
Boyle, J. J., Harrington, H. A., Piper, E., Elderfield, K., Stark, J., Landis, R. C., & Haskard, D. O. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.080431 · Cited by 319 · see citing works
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors
Kluk, M. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(02)00139-7 · Cited by 318 · see citing works
Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL
Lim, H. Y., Thiam, C. H., Yeo, K. P., Bisoendial, R. J., Hii, C. S., McGrath, K. C. Y., Tan, K. W., Heather, A. K., Alexander, J. S., & Angeli, V. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.04.002 · Cited by 309 · see citing works
Intimal vascularisation and atherosclerosis
Geiringer, E. (1951) · The Journal of Pathology and Bacteriology · doi:10.1002/path.1700630204 · Cited by 295 · see citing works
Haptoglobin: Basic and Clinical Aspects
Levy, A. P., Asleh, R., Blum, S., Levy, N. S., Miller‐Lotan, R., Kalet-Litman, S., Anbinder, Y., Lache, O., Nakhoul, F. M., Asaf, R., et al. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2793 · Cited by 294 · see citing works
Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia.
Kwon, H. M., Sangiorgi, G., Ritman, E. L., McKenna, C. J., Holmes, D. R., Schwartz, R., & Lerman, A. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1568 · Cited by 294 · see citing works
Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
Thurston, G. (2003) · Cell and Tissue Research · doi:10.1007/s00441-003-0749-6 · Cited by 292 · see citing works
Evolution and Classification of Cystine Knot-Containing Hormones and Related Extracellular Signaling Molecules
Vitt, U. A., Hsu, S. Y., & Hsueh, A. J. W. (2001) · Molecular Endocrinology · doi:10.1210/mend.15.5.0639 · Cited by 290 · see citing works
Vascular Endothelial Growth Factor D Is Dispensable for Development of the Lymphatic System
Baldwin, M. E., Halford, M. M., Roufail, S., Williams, R. A., Hibbs, M. L., Grail, D., Kubo, H., Stacker, S. A., & Achen, M. G. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2441-2449.2005 · Cited by 289 · see citing works
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
Mungrue, I. N., Gros, R., You, X., Pirani, A., Azad, A., Csont, T., Schulz, R., BUTANY, J. W., Stewart, D. J., & Husain, M. (2002) · Journal of Clinical Investigation · doi:10.1172/jci13265 · Cited by 286 · see citing works
Tumor Angiogenesis: Transfilter Diffusion Studies in the Hamster by the Transparent Chamber Technique 2
Greenblatt, M., & Shubi, P. (1968) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/41.1.111 · Cited by 283 · see citing works
Vascular endothelial grouth facter B, a novel growth facter for endothelial cells
Olffson, B. (1996) · Medical Entomology and Zoology · Cited by 279 · see citing works
Impaired Collateral Vessel Development Associated With Reduced Expression of Vascular Endothelial Growth Factor in ApoE −/− Mice
Couffinhal, T., Silver, M., Kearney, M., Sullivan, A. B., Witzenbichler, B., Magner, M., Annex, B. H., Peters, K. G., & Isner, J. M. (1999) · Circulation · doi:10.1161/01.cir.99.24.3188 · Cited by 274 · see citing works
The role of fibroblast growth factors in vascular development
Javerzat, S., Auguste, P., & Bikfalvi, A. (2002) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(02)02394-8 · Cited by 266 · see citing works
NO and angiogenesis
Cooke, J. P. (2003) · Atherosclerosis Supplements · doi:10.1016/s1567-5688(03)00034-5 · Cited by 266 · see citing works
Endothelial Progenitor Cells
Urbich, C., & Dimmeler, S. (2004) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2004.10.001 · Cited by 263 · see citing works
Akt Takes Center Stage in Angiogenesis Signaling
Dimmeler, S., & Zeiher, A. M. (2000) · Circulation Research · doi:10.1161/01.res.86.1.4 · Cited by 258 · see citing works
Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells.
Marumo, T., Schini‐Kerth, V. B., & Busse, R. (1999) · Diabetes · doi:10.2337/diabetes.48.5.1131 · Cited by 254 · see citing works
Genetic Deficiency of Inducible Nitric Oxide Synthase Reduces Atherosclerosis and Lowers Plasma Lipid Peroxides in Apolipoprotein E–Knockout Mice
Kuhlencordt, P. J., Chen, J., Han, F., Astern, J., & Huang, P. L. (2001) · Circulation · doi:10.1161/01.cir.103.25.3099 · Cited by 252 · see citing works
Cardiovascular roles of nitric oxide: A review of insights from nitric oxide synthase gene disrupted mice
Liu, V. W. T., & Huang, P. L. (2007) · Cardiovascular Research · doi:10.1016/j.cardiores.2007.06.024 · Cited by 252 · see citing works
VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond
Giacca, M., & Zacchigna, S. (2012) · Gene Therapy · doi:10.1038/gt.2012.17 · Cited by 252 · see citing works
Accelerated Restitution of Endothelial Integrity and Endothelium-Dependent Function After phVEGF 165 Gene Transfer
Asahara, T., Chen, D., Tsurumi, Y., Kearney, M., Rossow, S., Passeri, J. J., Symes, J. F., & Isner, J. M. (1996) · Circulation · doi:10.1161/01.cir.94.12.3291 · Cited by 249 · see citing works
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
Mungrue, I. N., Gros, R., You, X., Pirani, A., Azad, A., Csont, T., Schulz, R., BUTANY, J. W., Stewart, D. J., & Husain, M. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0213265 · Cited by 248 · see citing works
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3
Kimura, T., Watanabe, T., Sato, K., Kon, J., Tomura, H., Tamama, K., Kuwabara, A., Kanda, T., Kobayashi, I., Ohta, H., et al. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3480071 · Cited by 246 · see citing works
PlGF: A Multitasking Cytokine with Disease-Restricted ActivityPreprint
Dewerchin, M. A., & Carmeliet, P. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a011056 · Cited by 244 · see citing works
The dynamic vasa vasorum
Ritman, E. L., & Lerman, A. (2007) · Cardiovascular Research · doi:10.1016/j.cardiores.2007.06.020 · Cited by 242 · see citing works
Red Cells, Hemoglobin, Heme, Iron, and Atherogenesis
Nagy, E., Eaton, J. W., Jeney, V., Soares, M. P., Varga, Z., Galajda, Z., Szentmiklósi, J., Méhes, G., Csonka, T., Smith, A., et al. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.206433 · Cited by 239 · see citing works
Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2.
Griffith, E. C., Su, Z., Niwayama, S., Ramsay, C. A., Chang, Y.-H., & Liu, J. O. (1998) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.95.26.15183 · Cited by 238 · see citing works
VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level
Arcondéguy, T., Lacazette, É., Millevoi, S., Prats, H., & Touriol, C. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt539 · Cited by 237 · see citing works
VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications
Robciuc, M. R., Kivelä, R., Williams, I. M., de Boer, J. F., van Dijk, T. H., Elamaa, H. P., Tigistu‐Sahle, F., Molotkov, D. A., Leppänen, V., Käkelä, R., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.03.004 · Cited by 234 · see citing works
IL-8 Is an Angiogenic Factor in Human Coronary Atherectomy Tissue
Simonini, A. A., Moscucci, M. M., Muller, D. W., Bates, E., Pagani, F. D., Burdick, M. D., & Strieter, R. M. (2000) · Circulation · doi:10.1161/01.cir.101.13.1519 · Cited by 225 · see citing works
Genetic Ablation of Caveolin-1 Confers Protection Against Atherosclerosis
Frank, P. G., Lee, H., Park, D. S., Tandon, N. N., Scherer, P. E., & Lisanti, M. P. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000101182.89118.e5 · Cited by 224 · see citing works
Simvastatin Preserves the Structure of Coronary Adventitial Vasa Vasorum in Experimental Hypercholesterolemia Independent of Lipid Lowering
Wilson, S. H., Herrmann, J., Lerman, L. O., Holmes, D. R., Claudio Napoli, A., Ritman, E. L., & Lerman, A. (2002) · Circulation · doi:10.1161/hc0402.104119 · Cited by 221 · see citing works
Effect of Cholesterol Crystals on Plaques and Intima in Arteries of Patients With Acute Coronary and Cerebrovascular Syndromes
Abela, G. S., Aziz, K. S., Vedre, A., Pathak, D. R., Talbott, J. D., & deJong, J. L. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.12.019 · Cited by 215 · see citing works
Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way
Carmeliet, P., Smet, F. D., Loges, S., & Mazzone, M. (2009) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2009.64 · Cited by 213 · see citing works
Topological Determinants and Consequences of Adventitial Responses to Arterial Wall Injury
Michel, J., Thaunat, O., Houard, X., Meilhac, O., Caligiuri, G., & Nicoletti, A. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.106.137851 · Cited by 208 · see citing works
A Novel Mouse Model of Atherosclerotic Plaque Instability for Drug Testing and Mechanistic/Therapeutic Discoveries Using Gene and MicroRNA Expression Profiling
Chen, Y., Bui, A. V., Diesch, J., Manasseh, R., Hausding, C., Rivera, J., Haviv, I., Agrotis, A., Htun, N., Jowett, J. B. M., et al. (2013) · Circulation Research · doi:10.1161/circresaha.113.301562 · Cited by 206 · see citing works
Hypercholesterolemia Attenuates Angiogenesis but Does Not Preclude Augmentation by Angiogenic Cytokines
BELLE, E. V., Rivard, A., Chen, D., Silver, M., Bunting, S., Ferrara, N., Symes, J. F., Bauters, C., & Isner, J. M. (1997) · Circulation · doi:10.1161/01.cir.96.8.2667 · Cited by 200 · see citing works
Natural progression of atherosclerosis from pathologic intimal thickening to late fibroatheroma in human coronary arteries: A pathology study
Otsuka, F., Kramer, M. C. A., Woudstra, P., Yahagi, K., Ladich, E. R., Finn, A. V., de Winter, R. J., Kolodgie, F. D., Wight, T. N., Davis, H. R., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.05.011 · Cited by 199 · see citing works
Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos
Haiko, P., Mäkinen, T., Keskitalo, S., Taipale, J., Karkkainen, M. J., Baldwin, M. E., Stacker, S. A., Achen, M. G., & Alitalo, K. K. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.02214-07 · Cited by 199 · see citing works
The hypoxia‐inducible‐factor hydroxylases bring fresh air into hypoxia signalling
Berra, E., Ginouvès, A., & Pouysségur, J. (2006) · EMBO Reports · doi:10.1038/sj.embor.7400598 · Cited by 196 · see citing works
Control of angiogenesis by AIBP-mediated cholesterol efflux
Fang, L., Choi, S.-H., Baek, J. S., Liu, C., Almazan, F., Ulrich, F., Wiesner, P., Taleb, A., Deer, E., Pattison, J., et al. (2013) · Nature · doi:10.1038/nature12166 · Cited by 192 · see citing works
Transactivation of Vascular Endothelial Growth Factor (VEGF) Receptor Flk-1/KDR Is Involved in Sphingosine 1-Phosphate-stimulated Phosphorylation of Akt and Endothelial Nitric-oxide Synthase (eNOS)
Tanimoto, T., Jin, Z., & Berk, B. C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204764200 · Cited by 189 · see citing works
Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells
Yana, I., Sagara, H., Τακακι, S., Takatsu, K., Nakamura, K., Nakao, K., Katsuki, M., Taniguchi, S.-I., Aoki, T., Sato, H., et al. (2007) · Journal of Cell Science · doi:10.1242/jcs.000679 · Cited by 185 · see citing works
The Biology of Arteriosclerosis
Winternitz, M. C., Thomas, R. M., & LeCompte, P. M. (1938) · The American Journal of the Medical Sciences · doi:10.1097/00000441-193808000-00030 · Cited by 183 · see citing works
The epidermal growth factor receptors and their family of ligands: Their putative role in atherogenesis
Dreux, A. C., Lamb, D. J., Modjtahedi, H., & Ferns, G. A. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.06.038 · Cited by 183 · see citing works
Oxidized Phospholipids Stimulate Angiogenesis Via Autocrine Mechanisms, Implicating a Novel Role for Lipid Oxidation in the Evolution of Atherosclerotic Lesions
Bochkov, V. N., Philippova, M., Oskolkova, O., Kadl, A., Fürnkranz, A., Karabeg, E., Afonyushkin, T., Грубер, Ф., Breuss, J. M., Minchenko, О. H., et al. (2006) · Circulation Research · doi:10.1161/01.res.0000245485.04489.ee · Cited by 179 · see citing works
Vascular Endothelial Growth Factor-B in Physiology and Disease
Bry, M., Kivelä, R., Leppänen, V., & Alitalo, K. K. (2014) · Physiological Reviews · doi:10.1152/physrev.00028.2013 · Cited by 171 · see citing works
Pathology of human plaque vulnerability: Mechanisms and consequences of intraplaque haemorrhages
Michel, J., Martı́n-Ventura, J. L., Nicoletti, A., & Ho‐Tin‐Noé, B. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.03.020 · Cited by 171 · see citing works
VEGF, a prosurvival factor, acts in concert with TGF-β1 to induce endothelial cell apoptosis
Ferrari, G. M., Pintucci, G., Seghezzi, G., Hyman, K. M., Galloway, A. C., & Mignatti, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605556103 · Cited by 160 · see citing works
Placental Growth Factor Promotes Atherosclerotic Intimal Thickening and Macrophage Accumulation
Khurana, R., Moons, L., Shafi, S., Luttun, A., Collen, D., Martin, J. F., Carmeliet, P., & Zachary, I. C. (2005) · Circulation · doi:10.1161/circulationaha.104.495887 · Cited by 159 · see citing works
Involvement of intraplaque hemorrhage in atherothrombosis evolution via neutrophil protease enrichment
Leclercq, A., Houard, X., Philippe, M., Ollivier, V., Sebbag, U., Meilhac, O., & Michel, J. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.1106671 · Cited by 159 · see citing works
The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis
Cudmore, M., Hewett, P. W., Ahmad, S., Wang, K.-Q., Cai, M., Al‐Ani, B., Fujisawa, T., Ma, B., Sissaoui, S., Ramma, W., et al. (2012) · Nature Communications · doi:10.1038/ncomms1977 · Cited by 159 · see citing works
Induction of Vascular Endothelial Growth Factor in Balloon-Injured Baboon Arteries
Ruef, J., Hu, Z. Y., Yin, L.-Y., Wu, Y., Hanson, S. R., Kelly, A. B., Harker, L. A., Rao, G. N., Runge, M. S., & Patterson, C. (1997) · Circulation Research · doi:10.1161/01.res.81.1.24 · Cited by 158 · see citing works
Role of Endothelial Cell–Derived Angptl2 in Vascular Inflammation Leading to Endothelial Dysfunction and Atherosclerosis Progression
Horio, E., Kadomatsu, T., Miyata, K., Arai, Y., Hosokawa, K., Doi, Y., Ninomiya, T., Horiguchi, H., Endo, M., Tabata, M., et al. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.303116 · Cited by 157 · see citing works

Flagged first, then by citations

4 of the 334 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

[16]Geiringer E. Intimal vascularization and atherosclerosis J. Pathol. Bacteriol. 63 2 1951 201 211 14851161
[50]van Uden P. Kenneth N.S. Rocha S. Regulation of hypoxia-inducible factor-1alpha by NF-kappaB Biochem. J. 412 3 2008 477 484 18393939 PMC2474706

Sorted by citations

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Ajoolabady, A., Praticò, D., Lin, L., Mantzoros, C. S., Bahijri, S., Tuomilehto, J. O., & Ren, J. T. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-07166-8 · Cited by 510 · see citing works
VEGF-A in Cardiomyocytes and Heart Diseases
Braile, M., Marcella, S., Cristinziano, L., Galdiero, M. R., Modestino, L., Ferrara, A. L., Varricchi, G., Marone, G., & Loffredo, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155294 · Cited by 240 · see citing works
Tetramethylpyrazine: A review on its mechanisms and functions
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Coronary Atherosclerotic Plaque Regression
Dawson, L. P., Lum, M., Nerlekar, N., Nicholls, S. J., & Layland, J. J. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.10.035 · Cited by 198 · see citing works
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Higashi, Y., Gautam, S., Delafontaine, P., & Sukhanov, S. (2019) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2019.01.002 · Cited by 160 · see citing works
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Bao, M., Li, G., Huang, X., Tang, L., Dong, L., & Li, J. (2018) · Molecular Pharmacology · doi:10.1124/mol.117.110650 · Cited by 150 · see citing works
The multifaceted role of the SASP in atherosclerosis: from mechanisms to therapeutic opportunities
Sun, Y., Wang, X., Liu, T., Zhu, X., & Pan, X. (2022) · Cell & Bioscience · doi:10.1186/s13578-022-00815-5 · Cited by 151 · see citing works
96 perfusable blood vessels to study vascular permeability in vitro
van Duinen, V., van den Heuvel, A., Trietsch, S. J., Lanz, H. L., van Gils, J. M., van Zonneveld, A. J., Vulto, P., & Hankemeier, T. (2017) · Scientific Reports · doi:10.1038/s41598-017-14716-y · Cited by 130 · see citing works
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Ong, S. W. X., Fong, S., Young, B. E., Chan, Y., Lee, B. T. K., Amrun, S. N., Chee, R. S., Yeo, N. K., Tambyah, P. A., Pada, S., et al. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab156 · Cited by 113 · see citing works
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Ghosh, S., Luo, D., He, W., Chen, J., Su, X., & Huang, H. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104861 · Cited by 93 · see citing works
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He, H., Li, R., Choi, S., Zhou, L., Pavel, A. B., Estrada, Y. D., Krueger, J. G., & Guttman‐Yassky, E. (2019) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2019.10.013 · Cited by 87 · see citing works
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Liao, J., Chen, B., Zhu, Z., Du, C., Gao, S., Zhao, G., Zhao, P., Wang, Y., Wang, A., Schwartz, Z., et al. (2023) · Genes & Diseases · doi:10.1016/j.gendis.2023.02.008 · Cited by 76 · see citing works
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Ou, L.-C., Zhong, S., Ou, J., & Tian, J. (2020) · Acta Pharmacologica Sinica · doi:10.1038/s41401-020-0436-0 · Cited by 71 · see citing works
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Zhang, X., Centurion, F., Misra, A., Patel, S., & Gu, Z. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114709 · Cited by 72 · see citing works
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Linna-Kuosmanen, S., Kansanen, E., Kaikkonen, M. U., Sihvola, V., Pulkkinen, K. H., Jyrkkänen, H.-K., Tuoresmäki, P., Hartikainen, J. E. K., Hippeläinen, M., Kokki, H. J., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx1155 · Cited by 71 · see citing works
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Zhang, Y., Wernly, B., Cao, X., Mustafa, S. J., Tang, Y., & Zhou, Z. (2021) · Basic Research in Cardiology · doi:10.1007/s00395-021-00859-7 · Cited by 71 · see citing works
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Querio, G., Antoniotti, S., Geddo, F., Levi, R. C., & Gallo, M. P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065806 · Cited by 70 · see citing works
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Levy, D., Reichert, C. O., & Bydlowski, S. P. (2019) · Antioxidants · doi:10.3390/antiox8050118 · Cited by 58 · see citing works
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Platelet-Derived Exosomes Affect the Proliferation and Migration of Human Umbilical Vein Endothelial Cells Via miR-126
Sun, Y., Liu, X., Zhang, D., Liu, F., Cheng, Y., Ma, Y., Zhou, Y., & Zhao, Y. (2018) · Current Vascular Pharmacology · doi:10.2174/1570161116666180313142139 · Cited by 57 · see citing works
MicroRNA‐125b in vascular diseases: An updated systematic review of pathogenetic implications and clinical applications
Chao, C., Yeh, H., Yuan, T., Chiang, C., & Chen, H. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14535 · Cited by 52 · see citing works
Impairment of hypoxia-induced angiogenesis by LDL involves a HIF-centered signaling network linking inflammatory TNFα and angiogenic VEGF
Jin, F., Zheng, X., Yang, Y., Yao, G., Ye, L., Doeppner, T. R., Hermann, D. M., Wang, H., & Dai, Y. (2019) · Aging · doi:10.18632/aging.101726 · Cited by 51 · see citing works
Glycosylation as new pharmacological strategies for diseases associated with excessive angiogenesis
Bousseau, S., Vergori, L., Soleti, R., Lenaers, G., Martínez, M. C., & Andriantsitohaina, R. (2018) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.06.003 · Cited by 51 · see citing works
Impacts of aging and fluid shear stress on vascular endothelial metabolism and atherosclerosis development
Wang, W.-L., Shih, Y.-T., Wei, S.-Y., & Chiu, J.-J. (2025) · Journal of Biomedical Science · doi:10.1186/s12929-025-01177-z · Cited by 50 · see citing works
Hypoxia-Inducible Factor Regulates Endothelial Metabolism in Cardiovascular Disease
Ullah, K., & Wu, R. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.670653 · Cited by 50 · see citing works
IL-6 trans-Signaling Impairs Sprouting Angiogenesis by Inhibiting Migration, Proliferation and Tube Formation of Human Endothelial Cells
Zegeye, M. M., Andersson, B., Sirsjö, A., & Ljungberg, L. U. (2020) · Cells · doi:10.3390/cells9061414 · Cited by 50 · see citing works
Cardiovascular protection effect of chlorogenic acid: focus on the molecular mechanism
Lukitasari, M., Rohman, M. S., Nugroho, D. A., Widodo, N., & Nugrahini, N. I. P. (2020) · F1000Research · doi:10.12688/f1000research.26236.1 · Cited by 49 · see citing works
Transthyretin: From Structural Stability to Osteoarticular and Cardiovascular Diseases
Wieczorek, E., & Ożyhar, A. (2021) · Cells · doi:10.3390/cells10071768 · Cited by 49 · see citing works
Role of Angiogenesis and Its Biomarkers in Development of Targeted Tumor Therapies
Pathak, A., Pal, A. K., Roy, S., Nandave, M., & Jain, K. (2024) · Stem Cells International · doi:10.1155/2024/9077926 · Cited by 48 · see citing works
Cellular crosstalk in atherosclerotic plaque microenvironment
Mahdinia, E., Shokri, N., Taheri, A. T., Asgharzadeh, S., Elahimanesh, M., & Najafi, M. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01153-w · Cited by 46 · see citing works
Role of miR‐15a‐5p and miR‐199a‐3p in the inflammatory pathway regulated by NF‐κB in experimental and human atherosclerosis
González‐López, P., Álvarez‐Villarreal, M., Ruiz‐Simón, R., López‐Pastor, A. R., de Céniga, M. V., Esparza, L., Martı́n-Ventura, J. L., Escribano, Ó., & Gómez‐Hernández, A. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1363 · Cited by 46 · see citing works
Antioxidant and Anti-Inflammatory Properties of Cherry Extract: Nanosystems-Based Strategies to Improve Endothelial Function and Intestinal Absorption
Beconcini, D., Felice, F., Fabiano, A., Sarmento, B. F. C. C., Zambito, Y., & Stefano, R. D. (2020) · Foods · doi:10.3390/foods9020207 · Cited by 46 · see citing works
Long non-coding RNA H19 in atherosclerosis: what role?
Shi, X., Wei, Y., Li, H., Jiang, T., Zheng, X., Yin, K., & Zhao, G.-J. (2020) · Molecular Medicine · doi:10.1186/s10020-020-00196-w · Cited by 46 · see citing works
The Cardiovascular Therapeutic Potential of Propolis—A Comprehensive Review
Silva, H., Francisco, R. C., Saraiva, A., Francisco, S., Carrascosa, C., & Raposo, A. (2021) · Biology · doi:10.3390/biology10010027 · Cited by 71 · see citing works
Tanshinol borneol ester, a novel synthetic small molecule angiogenesis stimulator inspired by botanical formulations for angina pectoris
Liao, S., Han, L., Zheng, X., Wang, X., Zhang, P., Wu, J., Liu, R., Fu, Y.-L., Sun, J., Kang, X., et al. (2019) · British Journal of Pharmacology · doi:10.1111/bph.14714 · Cited by 43 · see citing works
Inhibitory effects of Paris saponin I, II, Ⅵ and Ⅶ on HUVEC cells through regulation of VEGFR2, PI3K/AKT/mTOR, Src/eNOS, PLCγ/ERK/MERK, and JAK2-STAT3 pathways
Wang, W., Liu, Y., You, L., Sun, M., Qu, C., Dong, X., Yin, X., & Ni, J. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110750 · Cited by 43 · see citing works
Atherosclerosis, Diabetes Mellitus, and Cancer: Common Epidemiology, Shared Mechanisms, and Future Management
Katsi, V. K., Papakonstantinou, I. P., & Tsioufis, K. P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241411786 · Cited by 42 · see citing works
Endothelial dysfunction: from the particular to the general. Return to the «Old Paradigm»?
Vlasov, T. D., Ивановна, Н. И., & Shimanski, D. A. (2019) · Regional blood circulation and microcirculation · doi:10.24884/1682-6655-2019-18-2-19-27 · Cited by 54 · see citing works
Biochemical and immunological changes in obesity
Barakat, B., & de Almeida, M. E. F. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2021.108951 · Cited by 42 · see citing works
LncRNA NORAD Promotes Vascular Endothelial Cell Injury and Atherosclerosis Through Suppressing VEGF Gene Transcription via Enhancing H3K9 Deacetylation by Recruiting HDAC6
Kai, H., Wu, Q., Yin, R., Tang, X., Shi, H., Wang, T., Zhang, M., & Pan, C. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.701628 · Cited by 42 · see citing works
Molecular Interactions Between Vascular Smooth Muscle Cells and Macrophages in Atherosclerosis
Beck-Joseph, J., Tabrizian, M., & Lehoux, S. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.737934 · Cited by 41 · see citing works
Impact of Chronic Psychological Stress on Cardiovascular Disease Risk: A Narrative Review
Munir, L. Z., & Toit, E. F. D. (2024) · Heart and Mind · doi:10.4103/hm.hm-d-24-00040 · Cited by 43 · see citing works
Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury
Bras, A. L., Yu, B., Bhaloo, S. I., Hong, X., Zhang, Z., Hu, Y., & Xu, Q. (2017) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.117.309853 · Cited by 40 · see citing works
MicroRNA-296: a promising target in the pathogenesis of atherosclerosis?
Li, H., Ouyang, X.-P., Jiang, T., Zheng, X., He, P., & Zhao, G.-J. (2018) · Molecular Medicine · doi:10.1186/s10020-018-0012-y · Cited by 40 · see citing works
Tetramethylpyrazine and Paeoniflorin Inhibit Oxidized LDL‐Induced Angiogenesis in Human Umbilical Vein Endothelial Cells via VEGF and Notch Pathways
Yuan, R., Shi, W., Xin, Q., Yang, B., Hoi, M. P. M., Lee, S. M., Cong, W., & Chen, K. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/3082507 · Cited by 40 · see citing works
RETRACTED ARTICLE: Melatonin enhances TNF-α-mediated cervical cancer HeLa cells death via suppressing CaMKII/Parkin/mitophagy axis
Zhao, Q., Wang, W., & Cui, J. (2019) · Cancer Cell International · doi:10.1186/s12935-019-0777-2 · Cited by 40 · see citing works
Retracted
Aortic valve: anatomy and structure and the role of vasculature in the degenerative process
Katsi, V. K., Magkas, N., Antonopoulos, A. S., Trantalis, G., Toutouzas, K. P., & Tousoulis, D. M. (2020) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2020.1746053 · Cited by 39 · see citing works
Advances in Glycolysis Metabolism of Atherosclerosis
Xu, R., Yuan, W., & Wang, Z. (2022) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-022-10311-3 · Cited by 41 · see citing works
Biomimetic 3D Models for Investigating the Role of Monocytes and Macrophages in Atherosclerosis
Garcia‐Sabaté, A., Mohamed, W. K. E. A., Sapudom, J., Alatoom, A., Safadi, L. A., & Teo, J. C. M. (2020) · Bioengineering · doi:10.3390/bioengineering7030113 · Cited by 39 · see citing works
Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice
van Keulen, D., Pouwer, M. G., Pasterkamp, G., van Gool, A. J., Gelpke, M. D. S., Princen, H. M. G., & Tempel, D. (2018) · PLoS ONE · doi:10.1371/journal.pone.0204911 · Cited by 38 · see citing works
Proteases: Pivot Points in Functional Proteomics
Verhamme, I. M., Leonard, S. E., & Perkins, R. C. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8814-3_20 · Cited by 39 · see citing works
Accelerated Atherosclerosis in Rheumatoid Arthritis: Mechanisms and Treatment
Reiss, A. B., Silverman, A., Khalfan, M., Vernice, N. A., Kasselman, L. J., Carsons, S. E., & Leon, J. D. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190430113212 · Cited by 38 · see citing works
Arterial Lymphatics in Atherosclerosis: Old Questions, New Insights, and Remaining Challenges
Csányi, G., & Singla, B. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8040495 · Cited by 37 · see citing works
Interleukin-22: a potential therapeutic target in atherosclerosis
Luo, J., Hu, Y., Liu, J., Yang, H. M., & Huang, P. (2021) · Molecular Medicine · doi:10.1186/s10020-021-00353-9 · Cited by 37 · see citing works
Protease‐Sensitive, VEGF‐Mimetic Peptide, and IKVAV Laminin‐Derived Peptide Sequences within Elastin‐Like Recombinamer Scaffolds Provide Spatiotemporally Synchronized Guidance of Angiogenesis and Neurogenesis
González‐Pérez, F., Alonso, M., de Torre, I. G., Santos, M., & Rodríguez‐Cabello, J. C. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202201646 · Cited by 37 · see citing works
Exogenous Bioactive Peptides Have a Potential Therapeutic Role in Delaying Aging in Rodent Models
Wang, J., Wu, Y., Chen, Z., Chen, Y., Lin, Q., & Liang, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031421 · Cited by 38 · see citing works
Mathematical modeling of atherosclerotic plaque destabilization: Role of neovascularization and intraplaque hemorrhage
Guo, M.-Y., Cai, Y., Yao, X., & Li, Z. (2018) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2018.04.031 · Cited by 36 · see citing works
The role of pigment epithelium-derived factor in protecting against cellular stress
Brook, N., Brook, E., Dharmarajan, A., Chan, A., & Dass, C. R. (2019) · Free Radical Research · doi:10.1080/10715762.2019.1697809 · Cited by 36 · see citing works
Carotid artery stenosis and inflammatory biomarkers: the role of inflammation-induced immunological responses affecting the vascular systems
Wijeratne, T., Menon, R., Sales, C., Karimi, L., & Crewther, S. G. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-4388 · Cited by 35 · see citing works
Inflammation in human carotid atheroma plaques
Goikuria, H., Vandenbroeck, K., & Alloza, I. (2018) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2018.01.006 · Cited by 35 · see citing works
Atherosclerosis and Toll-Like Receptor4 (TLR4), Lectin-Like Oxidized Low-Density Lipoprotein-1 (LOX-1), and Proprotein Convertase Subtilisin/Kexin Type9 (PCSK9)
Bagheri, B., Feyzabadi, Z. K., Nouri, A., Azadfallah, A., Ari, M. M., Hemati, M., Darban, M., Toosi, P. A., & Banihashemian, S. Z. (2024) · Mediators of Inflammation · doi:10.1155/2024/5830491 · Cited by 34 · see citing works
PA/US dual-modality imaging to guide VEGFR-2 targeted photothermal therapy using ZnPc-/PFH-loaded polymeric nanoparticles
Chen, Y., Liu, F.-Q., Guo, Y., Cheng, J., Yang, L., Lu, M., Li, P., Xu, J., Yu, T., Wang, Z., et al. (2018) · Biomaterials Science · doi:10.1039/c8bm00213d · Cited by 34 · see citing works
Macrophages in Atherosclerosis, First or Second Row Players?
Checkouri, É., Blanchard, V., & Meilhac, O. (2021) · Biomedicines · doi:10.3390/biomedicines9091214 · Cited by 35 · see citing works
Endothelial Cell Metabolism in Vascular Functions
Filippini, A., Tamagnone, L., & D’Alessio, A. (2022) · Cancers · doi:10.3390/cancers14081929 · Cited by 33 · see citing works
A novel curcumin-loaded nanoparticle restricts atherosclerosis development and promotes plaques stability in apolipoprotein E deficient mice
Meng, N., Yan Fang, G. O. N. G., Zhang, J., Mu, X., Song, Z., Feng, R., & Zhang, H. (2018) · Journal of Biomaterials Applications · doi:10.1177/0885328218815328 · Cited by 32 · see citing works
Modulation of Adhesion Process, E-Selectin and VEGF Production by Anthocyanins and Their Metabolites in an In Vitro Model of Atherosclerosis
Marino, M., Bo’, C. D., Tucci, M., Klimis‐Zacas, D. J., Riso, P., & Porrini, M. (2020) · Nutrients · doi:10.3390/nu12030655 · Cited by 31 · see citing works
The role of androgen receptors in atherosclerosis
Takov, K., Wu, J., Denvir, M. A., Smith, L. B., & Hadoke, P. W. F. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.10.006 · Cited by 31 · see citing works
Immunological perspectives on atherosclerotic plaque formation and progression
Pi, H., Wang, G., Wang, Y., Zhang, M., He, Q., Zheng, X., Yin, K., Zhao, G., & Jiang, T. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1437821 · Cited by 33 · see citing works
Association of Vitamin D Deficiency and Degree of Coronary Artery Disease in Cardiac Patients with Type 2 Diabetes
Dziedzic, E. A., Gąsior, J. S., Pawłowski, M., & Dąbrowski, M. (2017) · Journal of Diabetes Research · doi:10.1155/2017/3929075 · Cited by 30 · see citing works
Circulating Exosomal miRNAs as Novel Biomarkers for Stable Coronary Artery Disease
Zhang, P., Liang, T., Chen, Y., Wang, X., Wu, T., Xie, Z., Luo, J., Yu, Y., & Yu, H. (2020) · BioMed Research International · doi:10.1155/2020/3593962 · Cited by 30 · see citing works

Authors: Camaré, C., Pucelle, M., Nègre-Salvayre, A., & Salvayre, R.
Affiliations: Université Toulouse III - Paul Sabatier (FR)
Inserm (FR)
ORCID: Camaré, Caroline
Venue: Redox Biology
Publisher: Elsevier BV
Published: 2017-08
Volume: 12
Pages: 18-34
ISSN: 2213-2317 (ISSN-L)
DOI: 10.1016/j.redox.2017.01.007
PMC: PMC5312547
OpenAlex: W2585441851
Cited by: 401
References: 334
Citations by year: 2026: 18 · 2025: 39 · 2024: 61 · 2023: 62 · 2022: 49 · 2021: 55 · 2020: 44 · 2019: 36 · 2018: 28 · 2017: 9
FWCI: 3.29
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor)
Locations: Redox Biology (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
HAL (submittedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Institut National de la Santé et de la Recherche Médicale
Topics: Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cerebrovascular and Carotid Artery Diseases
Keywords: angiogenesis, atherosclerosis, atherosclerotic plaque, neovascularization, plaque vulnerability, anti-angiogenic therapy, vascular endothelial growth factor, VEGFR, atherothrombosis, thromboembolism, inflammation, cholesterol accumulation
MeSH terms: Animals, Clinical Trials as Topic, Humans, Neovascularization, Pathologic, Oxidative Stress, Disease Progression, Angiogenesis Inhibitors, Plaque, Atherosclerotic

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