NO and angiogenesis
Abstract
Angiogenesis requires the elaboration of endothelium-derived nitric oxide (NO). Angiogenic factors induce the release of NO from endothelial cells, which mediates a multiplicity of processes involved in angiogenesis. These NO-modulated processes include endothelial cell survival, proliferation, migration, and interaction with the extracellular matrix. Derangements of the NO synthase pathway impair angiogenesis. Accordingly, the competitive inhibitor of the NOS pathway asymmetric dimethylarginine (ADMA) acts as an endogenous inhibitor of angiogenesis. By contrast, agents which increase NO synthesis, such as low dose statins, enhance angiogenesis. Modulation of the NO synthase pathway could become a new therapeutic avenue for angiogenesis-related disorders.
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Multiple reports indicate that nitric oxide serves as an angiogenic signaling molecule, up-regulating VEGF production and increasing blood vessel growth.
“Multiple reports indicate that NO serves as an angiogenic signaling model, up-regulating VEGF production and increasing blood vessel growth.213–214”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [213]
Cites
Angiogenesis in cancer and other diseases
Carmeliet, P., & Jain, R. K. (2000) · Nature · doi:10.1038/35025220 · Cited by 9,070 · see citing works
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
Beckman, J. S., & Koppenol, W. H. (1996) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1996.271.5.c1424 · Cited by 5,513 · see citing works
Hypercholesterolemia increases endothelial superoxide anion production.
Ohara, Y., Peterson, T. E., & Harrison, D. G. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116491 · Cited by 1,765 · see citing works
Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
Vásquez-Vivar, J., Kalyanaraman, B., Martásek, P., Hogg, N., Masters, B. S. S., Karoui, H., Tordo, P., & Pritchard, K. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9220 · Cited by 1,484 · see citing works
Kureishi, Y., Luo, Z., Shiojima, I., Bialik, A., Fulton, D. J., Lefer, D. J., Sessa, W. C., & Walsh, K. (2000) · Nature Medicine · doi:10.1038/79510 · Cited by 1,437 · see citing works
Statins as a newly recognized type of immunomodulator.
Kwak, B., Mulhaupt, F., Myit, S., & Mach, F. (2000) · Nature Medicine · doi:10.1038/82219 · Cited by 1,383 · see citing works
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.
Murohara, T., Asahara, T., Silver, M., Bauters, C., Masuda, H., Kalka, C., Kearney, M., Chen, D., Symes, J. F., Fishman, M. C., et al. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1560 · Cited by 1,201 · see citing works
Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
Rubanyi, G. M., & Vanhoutte, P. M. (1986) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1986.250.5.h822 · Cited by 1,192 · see citing works
Papapetropoulos, A., García‐Cardeña, G., Madri, J. A., & Sessa, W. C. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119868 · Cited by 1,192 · see citing works
Böger, R. H., Bode-Böger, S. M., Szuba, A., Tsao, P. S., Chan, J. R., Tangphao, O., Blaschke, T. F., & Cooke, J. P. (1998) · Circulation · doi:10.1161/01.cir.98.18.1842 · Cited by 1,181 · see citing works
Self-citationZiche, M., Morbidelli, L., Choudhuri, R., Zhang, H. T., Donnini, S., Granger, H. J., & Bicknell, R. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119451 · Cited by 914 · see citing works
Ziche, M., Morbidelli, L., Masini, E., Amerini, S., Granger, H. J., Maggi, C. A., Geppetti, P., & Ledda, F. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117557 · Cited by 861 · see citing works
Griffioen, A. W., & Molema, G. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01448-0 · Cited by 843 · see citing works
Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis
Heeschen, C., Jang, J. J., Weis, M., Pathak, A., Kaji, S., Hu, R. S., Tsao, P. S., Johnson, F. L., & Cooke, J. P. (2001) · Nature Medicine · doi:10.1038/89961 · Cited by 800 · see citing works
Self-citationHernández‐Perera, O., Pérez‐Sala, D., Navarro-Antolı́n, J., Sánchez-Pascuala, R., Hernández, G., Dı́az-Jullien, C., & Lamas, S. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1500 · Cited by 764 · see citing works
Generation of superoxide by purified brain nitric oxide synthase
Pou, S., Pou, W. S., Bredt, D. S., Snyder, S. H., & Rosen, G. M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)35745-4 · Cited by 750 · see citing works
NITRIC OXIDE SYNTHASE: Role in the Genesis of Vascular Disease
Cooke, J. P., & Dzau, V. J. (1997) · Annual Review of Medicine · doi:10.1146/annurev.med.48.1.489 · Cited by 710 · see citing works
Self-citationVascular endothelial growth factor enhances atherosclerotic plaque progression
Celletti, F. L., Waugh, J. M., Amabile, P. G., Brendolan, A., Hilfiker, P. R., & Dake, M. D. (2001) · Nature Medicine · doi:10.1038/86490 · Cited by 708 · see citing works
Superoxide Generation from Endothelial Nitric-oxide Synthase
Xia, Y., Tsai, A.-L., Berka, V., & Zweier, J. L. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.40.25804 · Cited by 705 · see citing works
VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells
Hood, J. D., Meininger, C. J., Ziche, M., & Granger, H. J. (1998) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1998.274.3.h1054 · Cited by 696 · see citing works
Moulton, K. S., Heller, E., Konerding, M. A., Flynn, E., Palinski, W., & Folkman, J. (1999) · Circulation · doi:10.1161/01.cir.99.13.1726 · Cited by 688 · see citing works
Statins Have Biphasic Effects on Angiogenesis
Weis, M., Heeschen, C., Glassford, A. J., & Cooke, J. P. (2002) · Circulation · doi:10.1161/hc0602.103393 · Cited by 677 · see citing works
Self-citationHomocysteine Impairs the Nitric Oxide Synthase Pathway
Stuehlinger, M., Tsao, P. S., Her, J. H., Kimoto, M., Balint, R. F., & Cooke, J. P. (2001) · Circulation · doi:10.1161/hc4601.098514 · Cited by 662 · see citing works
Self-citationImpaired Nitric Oxide Synthase Pathway in Diabetes Mellitus
Lin, K. Y., Ito, A., Asagami, T., Tsao, P. S., Adimoolam, S., Kimoto, M., Tsuji, H., Reaven, G. M., & Cooke, J. P. (2002) · Circulation · doi:10.1161/01.cir.0000027109.14149.67 · Cited by 651 · see citing works
Self-citationNovel Mechanism for Endothelial Dysfunction
Ito, A., Tsao, P. S., Adimoolam, S., Kimoto, M., Ogawa, T., & Cooke, J. P. (1999) · Circulation · doi:10.1161/01.cir.99.24.3092 · Cited by 629 · see citing works
Self-citationTetrahydrobiopterin restores endothelial function in hypercholesterolemia.
Stroes, E. S. G., Kastelein, J. J. P., Cosentino, F., Erkelens, W. D., Wever, R. M. F., Koomans, H. A., Lüscher, T. F., & Rabelink, T. J. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119131 · Cited by 588 · see citing works
Relationship Between Insulin Resistance and an Endogenous Nitric Oxide Synthase Inhibitor
Stuehlinger, M. (2002) · JAMA · doi:10.1001/jama.287.11.1420 · Cited by 581 · see citing works
Oxidized Low-density Lipoprotein Decreases the Expression of Endothelial Nitric Oxide Synthase
Liao, J. K., Shin, W. S., Lee, W. Y., & Clark, S. L. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.1.319 · Cited by 541 · see citing works
Pritchard, K. A., Groszek, L., Smalley, D. M., Sessa, W. C., Wu, M., Villalon, P., Wolin, M. S., & Stemerman, M. B. (1995) · Circulation Research · doi:10.1161/01.res.77.3.510 · Cited by 471 · see citing works
Endogenous Dimethylarginine as an Inhibitor of Nitric Oxide Synthesis
Vallance, P. J., Leone, A. M., Calver, A., Collier, J., & Moncada, S. (1992) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199204002-00018 · Cited by 469 · see citing works
Sterols and Isoprenoids: Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway
Edwards, P. A., & Ericsson, J. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.157 · Cited by 458 · see citing works
Nitric Oxide Inhibits Caspase-3 by S-Nitrosationin Vivo
Rössig, L., Fichtlscherer, B., Breitschopf, K., Haendeler, J., Zeiher, A. M., Mülsch, A., & Dimmeler, S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.11.6823 · Cited by 432 · see citing works
Endothelium-Dependent Effects of Statins
Wolfrum, S., Jensen, K. S., & Liao, J. K. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000063385.12476.a7 · Cited by 418 · see citing works
Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium
Morbidelli, L., Chang, C.-H., Douglas, J. G., Granger, H. J., Ledda, F., & Ziche, M. (1996) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1996.270.1.h411 · Cited by 417 · see citing works
van der Zee, R., Murohara, T., Luo, Z., Zollmann, F. S., Passeri, J. J., Lekutat, C., & Isner, J. M. (1997) · Circulation · doi:10.1161/01.cir.95.4.1030 · Cited by 399 · see citing works
Statin-Sensitive Dysregulated AT1 Receptor Function and Density in Hypercholesterolemic Men
Nickenig, G., Bäumer, A. T., Temur, Y., Kebben, D., Jockenhövel, F., & Böhm, M. (1999) · Circulation · doi:10.1161/01.cir.100.21.2131 · Cited by 396 · see citing works
Reduced Endothelial Nitric Oxide Synthase Expression and Production in Human Atherosclerosis
Oemar, B. S., Tschudi, M. R., Godoy, N., Brovkovich, V. M., Maliñski, T., & Lüscher, T. F. (1998) · Circulation · doi:10.1161/01.cir.97.25.2494 · Cited by 396 · see citing works
Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase
MacAllister, R. J., Parry, H., Kimoto, M., Ogawa, T., Russell, R. J., Hodson, H. F., Whitley, G. S. J., & Vallance, P. J. (1996) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1996.tb16069.x · Cited by 394 · see citing works
Huang, A., Vita, J. A., Venema, R. C., & Keaney, J. F. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002248200 · Cited by 365 · see citing works
Abbasi, F., Asagmi, T., Cooke, J. P., Lamendola, C. A., McLaughlin, T., Reaven, G. M., Stuehlinger, M., & Tsao, P. S. (2001) · The American Journal of Cardiology · doi:10.1016/s0002-9149(01)02063-x · Cited by 354 · see citing works
Self-citationDulak, J., Józkowicz, A., Dembinska-Kiec, A., Guevara, I., Zdzienicka, A., Zmudzinska-Grochot, D., Florek, I., Wójtowicz, A. K., Szuba, A., & Cooke, J. P. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.3.659 · Cited by 329 · see citing works
Self-citation3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors and the Risk of Cancer
Blais, L., Desgagné, A., & LeLorier, J. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.15.2363 · Cited by 326 · see citing works
Simon, B. C., Cunningham, L., & Cohen, R. A. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114718 · Cited by 311 · see citing works
Double-Edged Role of Statins in Angiogenesis Signaling
Urbich, C., Dernbach, E., Zeiher, A. M., & Dimmeler, S. (2002) · Circulation Research · doi:10.1161/01.res.0000014081.30867.f8 · Cited by 305 · see citing works
Bode‐Böger, S. M., Böger, R. H., Kienke, S., Junker, W., & Frölich, J. C. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0279 · Cited by 303 · see citing works
Dimmeler, S., Hermann, C., Galle, J., & Zeiher, A. M. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.3.656 · Cited by 300 · see citing works
Inhibition of Monocyte Chemotactic Protein-1 Synthesis by Statins
Romano, M., Diomede, L., Sironi, M., Massimiliano, L., Sottocorno, M., Polentarutti, N., Guglielmotti, A., Albani, D., Bruno, A., Fruscella, P., et al. (2000) · Laboratory Investigation · doi:10.1038/labinvest.3780115 · Cited by 298 · see citing works
LEIPER, J. M., Murray‐Rust, J., McDonald, N. Q., & Vallance, P. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.212269799 · Cited by 288 · see citing works
Park, H., Kong, D., Iruela‐Arispe, M. L., Begley, U., Tang, D., & Galper, J. (2002) · Circulation Research · doi:10.1161/01.res.0000028149.15986.4c · Cited by 274 · see citing works
Pedersen, T. R., Wilhelmsen, L., Færgeman, O., Strandberg, T. E., Þorgeirsson, G., Troedsson, L., Kristianson, J., Berg, K., Cook, T. J., Haghfelt, T. H., et al. (2000) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)00910-3 · Cited by 273 · see citing works
Hsp90 and Caveolin Are Key Targets for the Proangiogenic Nitric Oxide–Mediated Effects of Statins
Brouet, A., Sonveaux, P., Dessy, C., Moniotte, S., Balligand, J., & Féron, O. (2001) · Circulation Research · doi:10.1161/hh2201.100319 · Cited by 269 · see citing works
Lundman, P., Eriksson, M. J., Stuehlinger, M., Cooke, J. P., Hamsten, A., & Tornvall, P. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01318-3 · Cited by 236 · see citing works
Self-citationZiche, M., Parenti, A., Ledda, F., Dell’Era, P., Granger, H. J., Maggi, C. A., & Presta, M. (1997) · Circulation Research · doi:10.1161/01.res.80.6.845 · Cited by 207 · see citing works
Role of Nitric Oxide in the Angiogenic Response In Vitro to Basic Fibroblast Growth Factor
Babaei, S., Teichert-Kuliszewska, K., Monge, J. C., Mohamed, F., Bendeck, M. P., & Stewart, D. J. (1998) · Circulation Research · doi:10.1161/01.res.82.9.1007 · Cited by 205 · see citing works
BELLE, E. V., Rivard, A., Chen, D., Silver, M., Bunting, S., Ferrara, N., Symes, J. F., Bauters, C., & Isner, J. M. (1997) · Circulation · doi:10.1161/01.cir.96.8.2667 · Cited by 200 · see citing works
Inoue, N., Venema, R. C., Sayegh, H. S., Ohara, Y., Murphy, T. J., & Harrison, D. G. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.8.1255 · Cited by 192 · see citing works
Podokinesis in endothelial cell migration: role of nitric oxide
Noiri, E., Lee, E., Testa, J. E., Quigley, J. P., Colflesh, D. E., Keese, C. R., Giæver, I., & Goligorsky, M. S. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.274.1.c236 · Cited by 181 · see citing works
Asagami, T., Abbasi, F., Stuelinger, M., Lamendola, C. A., McLaughlin, T., Cooke, J. P., Reaven, G. M., & Tsao, P. S. (2002) · Metabolism · doi:10.1053/meta.2002.33349 · Cited by 164 · see citing works
Self-citationMacAllister, R. J., Fickling, S. A., Whitley, G. S. J., & Vallance, P. J. (1994) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1994.tb13026.x · Cited by 162 · see citing works
Ogawa, T., Kimoto, M., & Sasaoka, K. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)90929-6 · Cited by 155 · see citing works
Limb Blood Flow During Exercise Is Dependent on Nitric Oxide
Maxwell, A. J., Schauble, E. H., Bernstein, D., & Cooke, J. P. (1998) · Circulation · doi:10.1161/01.cir.98.4.369 · Cited by 147 · see citing works
Self-citationAsymmetric Dimethylarginine Increases Mononuclear Cell Adhesiveness in Hypercholesterolemic Humans
Chan, J. R., Böger, R. H., Bode‐Böger, S. M., Tangphao, O., Tsao, P. S., Blaschke, T. F., & Cooke, J. P. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.4.1040 · Cited by 140 · see citing works
Self-citationWeis, M., Pehlivanli, S., Meiser, B. M., & von Scheidt, W. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01430-9 · Cited by 135 · see citing works
Fluvastatin Inhibits Matrix Metalloproteinase-1 Expression in Human Vascular Endothelial Cells
Ikeda, U., Shimpo, M., Ohki, R., Inaba, H., Takahashi, M., Yamamoto, K., & Shimada, K. (2000) · Hypertension · doi:10.1161/01.hyp.36.3.325 · Cited by 133 · see citing works
Vincent, L., Soria, C., Mirshahi, F., Opolon, P., Mishal, Z., Vannier, J., Soria, J., & Li, H. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000012283.15789.67 · Cited by 129 · see citing works
Is Physiological Angiogenesis in Skeletal Muscle Regulated by Changes in Microcirculation?
HUDLICKÁ, O. (1998) · Microcirculation · doi:10.1111/j.1549-8719.1998.tb00048.x · Cited by 120 · see citing works
Papapetropoulos, A., Desai, K. M., Rudic, R. D., Mayer, B., Zhang, R., Ruiz‐Torres, M. P., García‐Cardeña, G., Madri, J. A., & Sessa, W. C. (1997) · Europe PMC (PubMed Central) · Cited by 119 · see citing works
Bacterial Toxins Block Endothelial Wound Repair
Aepfelbacher, M., Essler, M., Huber, E., Sugai, M., & Weber, P. C. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.9.1623 · Cited by 102 · see citing works
Knapp, A. C., Huang, J., Starling, G. C., & Kiener, P. A. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00462-1 · Cited by 95 · see citing works
Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis
Kostourou, V., Robinson, S. P., Cartwright, J. E., & Whitley, G. S. J. (2002) · British Journal of Cancer · doi:10.1038/sj.bjc.6600518 · Cited by 90 · see citing works
Fajardo, L. F., Kowalski, J., Kwan, H. H., Prionas, S. D., & ALLISON, A. C. (1988) · PubMed · Cited by 80 · see citing works
Chen, C., Cartwright, J., Li, Z., Lou, S., Nguyen, H. H., Gotto, A. M., & Henry, P. D. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.7.1303 · Cited by 74 · see citing works
Gingras, D., Lamy, S., & Béliveau, R. (2000) · Biochemical Journal · doi:10.1042/bj3480273 · Cited by 64 · see citing works
Acidic and basic FGFs dilate arterioles of skeletal muscle through a NO-dependent mechanism
Wu, H. M., Yuan, Y., McCarthy, M. A., & Granger, H. J. (1996) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1996.271.3.h1087 · Cited by 58 · see citing works
Tiefenbacher, C., & Chilian, W. M. (1997) · Cardiovascular Research · doi:10.1016/s0008-6363(97)00029-1 · Cited by 48 · see citing works
Characterization and applications of the disc angiogenesis system
Kowalski, J., Kwan, H. H., Prionas, S. D., ALLISON, A. C., & Fajardo, L. F. (1992) · Experimental and Molecular Pathology · doi:10.1016/0014-4800(92)90019-8 · Cited by 42 · see citing works
Chen, C.-H., & Henry, P. D. (1997) · PubMed · Cited by 40 · see citing works
Flagged first, then by citations
1 of the 78 references couldn’t be matched to a known paper.
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Oxidative Stress and Oxidative Damage in Carcinogenesis
Klaunig, J. E., Kamendulis, L. M., & Hocevar, B. A. (2009) · Toxicologic Pathology · doi:10.1177/0192623309356453 · Cited by 960 · see citing works
Hypoxia: A key regulator of angiogenesis in cancer
Liao, D., & Johnson, R. S. (2007) · Cancer and Metastasis Reviews · doi:10.1007/s10555-007-9066-y · Cited by 720 · see citing works
Oxidative stress and oxidative damage in chemical carcinogenesis
Klaunig, J. E., Wang, Z., Pu, X., & Zhou, S. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.11.028 · Cited by 475 · see citing works
Zhao, Y. D., Courtman, D. W., Deng, Y., Kugathasan, L., Zhang, Q., & Stewart, D. J. (2005) · Circulation Research · doi:10.1161/01.res.0000157672.70560.7b · Cited by 469 · see citing works
Pathological aspects of lipid peroxidation
Nègre‐Salvayre, A., Augè, N., Ayala, V., Başağa, H., Boada, J., Brenke, R., Chapple, S. J., Cohen, G., Fehér, J., Grune, T., et al. (2010) · Free Radical Research · doi:10.3109/10715762.2010.498478 · Cited by 451 · see citing works
Williams, R. J., & Spencer, J. P. E. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.010 · Cited by 448 · see citing works
Nitric Oxide and the Vascular Endothelium
Moncada, S., & Higgs, E. A. (2006) · Springer eBooks · doi:10.1007/3-540-32967-6_7 · Cited by 408 · see citing works
Angiogenesis in the atherosclerotic plaque
Camaré, C., Pucelle, M., Nègre-Salvayre, A., & Salvayre, R. (2017) · Redox Biology · doi:10.1016/j.redox.2017.01.007 · Cited by 401 · see citing works
Asymmetrical Dimethylarginine: The Über Marker?
Cooke, J. P. (2004) · Circulation · doi:10.1161/01.cir.0000126823.07732.d5 · Cited by 396 · see citing works
Self-citationApplications of Chitin and Its Derivatives in Biological Medicine
Park, B. K., & Kim, M. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11125152 · Cited by 378 · see citing works
The yin and yang of nitric oxide in cancer progression
Burke, A. J., Sullivan, F. J., Giles, F. J., & Glynn, S. A. (2013) · Carcinogenesis · doi:10.1093/carcin/bgt034 · Cited by 372 · see citing works
Biocompatible Materials for Continuous Glucose Monitoring Devices
Nichols, S. P., Koh, A., Storm, W. L., Shin, J. H., & Schoenfisch, M. H. (2013) · Chemical Reviews · doi:10.1021/cr300387j · Cited by 347 · see citing works
Palm, F., Onozato, M. L., Luo, Z., & Wilcox, C. S. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00998.2007 · Cited by 337 · see citing works
Isenberg, J. S., Ridnour, L. A., Dimitry, J. M., Frazier, W. A., Wink, D. A., & Roberts, D. D. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m605040200 · Cited by 291 · see citing works
Chen, J., Zacharek, A., Zhang, C., Jiang, H., Li, Y., Roberts, C., Lu, M., Kapke, A., & Chopp, M. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.5071-04.2005 · Cited by 287 · see citing works
Calabrese, E. J. (2008) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2008.03243.x · Cited by 263 · see citing works
Combating medical device fouling
Harding, J. L., & Reynolds, M. M. (2014) · Trends in biotechnology · doi:10.1016/j.tibtech.2013.12.004 · Cited by 261 · see citing works
The biphasic nature of nitric oxide responses in tumor biology
Ridnour, L. A., Thomas, D. D., Donzelli, S., Espey, M. G., Roberts, D. D., Wink, D. A., & Isenberg, J. S. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.1329 · Cited by 247 · see citing works
Regulation of Placental Angiogenesis
Chen, D., & Zheng, J. J. (2013) · Microcirculation · doi:10.1111/micc.12093 · Cited by 245 · see citing works
Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects
Spencer, J. P. E., Vauzour, D., & Rendeiro, C. (2009) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2009.10.003 · Cited by 228 · see citing works
Defective Mitochondrial Biogenesis
Nisoli, E., Clementi, E., Carruba, M. O., & Moncada, S. (2007) · Circulation Research · doi:10.1161/01.res.0000259591.97107.6c · Cited by 224 · see citing works
The impact of flavonoids on memory: physiological and molecular considerations
Spencer, J. P. E. (2009) · Chemical Society Reviews · doi:10.1039/b800422f · Cited by 219 · see citing works
Wang, Y., Wei, X., Xiao, X., Hui, R., Card, J. W., Carey, M. A., Wang, D. W., & Zeldin, D. C. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.083477 · Cited by 205 · see citing works
Angiogenic growth factors and hypertension
Sane, D. C., Anton, L., & Brosnihan, K. B. (2004) · Angiogenesis · doi:10.1007/s10456-004-2699-3 · Cited by 197 · see citing works
Tumur, Z., & Niwa, T. (2009) · American Journal of Nephrology · doi:10.1159/000191468 · Cited by 192 · see citing works
Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis
Kumar, D., Branch, B. G., Pattillo, C. B., Hood, J., Thoma, S., Simpson, S., Illum, S., Arora, N., Chidlow, J. H., Langston, W., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711480105 · Cited by 187 · see citing works
Teerlink, T. (2005) · Vascular Medicine · doi:10.1191/1358863x05vm597oa · Cited by 184 · see citing works
The mechanisms of action of flavonoids in the brain: Direct versus indirect effects
Rendeiro, C., Rhodes, J. S., & Spencer, J. P. E. (2015) · Neurochemistry International · doi:10.1016/j.neuint.2015.08.002 · Cited by 182 · see citing works
The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis
LEIPER, J. M., & Nandi, M. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3358 · Cited by 176 · see citing works
Hydrogen Sulfide Attenuates Cardiac Dysfunction After Heart Failure Via Induction of Angiogenesis
Polhemus, D. J., Kondo, K., Bhushan, S., Bir, S. C., Kevil, C. G., Murohara, T., Lefer, D. J., & Calvert, J. W. (2013) · Circulation Heart Failure · doi:10.1161/circheartfailure.113.000299 · Cited by 171 · see citing works
Reduced foreign body response at nitric oxide-releasing subcutaneous implants
Hetrick, E. M., Prichard, H. L., Klitzman, B., & Schoenfisch, M. H. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.06.036 · Cited by 158 · see citing works
Mechanisms of target organ damage caused by hypertension: Therapeutic potential
Cohuet, G., & Struijker-Boudier, H. A. J. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.09.002 · Cited by 158 · see citing works
Urbich, C., Rössig, L., Kaluza, D., Potente, M., Boeckel, J., Knau, A., Diehl, F., Geng, J.-G., Hofmann, W., Zeiher, A. M., et al. (2009) · Blood · doi:10.1182/blood-2009-01-196485 · Cited by 153 · see citing works
Local delivery of nitric oxide: Targeted delivery of therapeutics to bone and connective tissues
Nichols, S. P., Storm, W. L., Koh, A., & Schoenfisch, M. H. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.03.002 · Cited by 148 · see citing works
Intracellular Calcium, Endothelial Cells and Angiogenesis
Munaron, L. (2006) · Recent Patents on Anti-Cancer Drug Discovery · doi:10.2174/157489206775246502 · Cited by 134 · see citing works
ADMA: its role in vascular disease
Cooke, J. P. (2005) · Vascular Medicine · doi:10.1177/1358836x0501000103 · Cited by 131 · see citing works
Self-citationThe significant role of amino acid metabolic reprogramming in cancer
Liu, X., Ren, B., Ren, J., Gu, M., You, L., & Zhao, Y.-P. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01760-1 · Cited by 135 · see citing works
Isenberg, J. S., Hyodo, F., Matsumoto, K.-I., Romeo, M. J., Abu-Asab, M. S., Tsokos, M., Kuppusamy, P., Wink, D. A., Krishna, M. C., & Roberts, D. D. (2006) · Blood · doi:10.1182/blood-2006-08-041368 · Cited by 124 · see citing works
Update on vascular endothelial Ca2+signalling: A tale of ion channels, pumps and transporters
Moccia, F. D. (2012) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v3.i7.127 · Cited by 119 · see citing works
The Emerging Role of the Thioredoxin System in Angiogenesis
Dunn, L., Buckle, A., Cooke, J. P., & Ng, M. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.209643 · Cited by 119 · see citing works
Self-citationTargeted delivery of nitric oxide via a ‘bump-and-hole’-based enzyme–prodrug pair
Hou, J., Pan, Y., Zhu, D., Fan, Y., Feng, G., Wei, Y., Wang, H., Qin, K., Zhao, T., Yang, Q., et al. (2018) · Nature Chemical Biology · doi:10.1038/s41589-018-0190-5 · Cited by 117 · see citing works
Update on therapeutic neovascularization
Cao, Y., Hong, A., Schulten, H., & Post, M. J. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.11.020 · Cited by 115 · see citing works
Wegiel, B., Gallo, D. J., Raman, K. G., Karlsson, J. M., Ozanich, B. A., Chin, B. Y., Tzeng, E., Ahmad, S., Ahmed, A., Baty, C. J., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.887695 · Cited by 113 · see citing works
Nitric Oxide Physiology and Pathology
Hirst, D. G., & Robson, T. (2010) · Methods in molecular biology · doi:10.1007/978-1-61737-964-2_1 · Cited by 112 · see citing works
Continuous Glucose Monitoring: 40 Years, What We′ve Learned and What’s Next
Gifford, R. (2013) · ChemPhysChem · doi:10.1002/cphc.201300172 · Cited by 98 · see citing works
Nuzzo, A. M., Camm, E. J., Sferruzzi-Perri, A. N., Ashmore, T. J., Yung, H. W., Cindrová‐Davies, T., Spiroski, A., Sutherland, M. R., Logan, A., Austin‐Williams, S., et al. (2018) · American Journal Of Pathology · doi:10.1016/j.ajpath.2018.07.027 · Cited by 94 · see citing works
Stöber Synthesis of Nitric Oxide-Releasing S-Nitrosothiol-Modified Silica Particles
Riccio, D. A., Nugent, J. L., & Schoenfisch, M. H. (2011) · Chemistry of Materials · doi:10.1021/cm102510q · Cited by 93 · see citing works
Nonthermal electromagnetic fields: From first messenger to therapeutic applications
Pilla, A. A. (2013) · Electromagnetic Biology and Medicine · doi:10.3109/15368378.2013.776335 · Cited by 92 · see citing works
The ADMA/DDAH pathway is a critical regulator of endothelial cell motility
Wójciak‐Stothard, B., Torondel, B., Tsang, L. Y. F., Fleming, I., Fißlthaler, B., LEIPER, J. M., & Vallance, P. J. (2007) · Journal of Cell Science · doi:10.1242/jcs.002212 · Cited by 92 · see citing works
Microvascular Regeneration in Established Pulmonary Hypertension by Angiogenic Gene Transfer
Zhao, Y. D., Courtman, D. W., Ng, D. S., Robb, M. J., Deng, Y., Trogadis, J. E., Han, R. N. N., & Stewart, D. J. (2006) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2005-0115oc · Cited by 89 · see citing works
Sildenafil Promotes Ischemia-Induced Angiogenesis Through a PKG-Dependent Pathway
Senthilkumar, A., Smith, R. D., Khitha, J., Arora, N., Veerareddy, S., Langston, W., Chidlow, J. H., Barlow, S. C., Teng, X., Patel, R. P., et al. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.147421 · Cited by 91 · see citing works
LDL biochemical modifications: a link between atherosclerosis and aging
Alique, M., Luna, C., Carracedo, J., & Ramı́rez, R. (2015) · Food & Nutrition Research · doi:10.3402/fnr.v59.29240 · Cited by 90 · see citing works
Noordhuis, M. G., Eijsink, J. J. H., Roossink, F., de Graeff, P., Pras, E., Schuuring, E. M. D., Wisman, G. B. A., de Bock, G. H., & van der Zee, A. G. J. (2011) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2010.09.043 · Cited by 89 · see citing works
Speer, P. D., Powers, R. W., Frank, M. P., Harger, G. F., Marković, N., & Roberts, J. M. (2008) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2007.05.052 · Cited by 88 · see citing works
Transition‐Metal Nitrosyls for Photocontrolled Nitric Oxide Delivery
Xiang, H., Guo, M., & Liu, J. (2016) · European Journal of Inorganic Chemistry · doi:10.1002/ejic.201601135 · Cited by 83 · see citing works
Hulin, J.-A., Tommasi, S., Elliot, D. J., Hu, D. G., Lewis, B. C., & Mangoni, A. A. (2017) · Scientific Reports · doi:10.1038/s41598-017-14454-1 · Cited by 80 · see citing works
Endothelial Remodelling and Intracellular Calcium Machinery
Moccia, F. D., Tanzi, F., & Munaron, L. (2014) · Current Molecular Medicine · doi:10.2174/1566524013666131118113410 · Cited by 80 · see citing works
Castiglione, N., Rinaldo, S., Giardina, G., Stelitano, V., & Cutruzzolà, F. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4196 · Cited by 79 · see citing works
Patel, V. I., Daniel, S., Longo, C. R., Shrikhande, G., Scali, S. T., Czismadia, E., Groft, C. M., Shukri, T., Mottley, C., Ramsey, H. E., et al. (2006) · The FASEB Journal · doi:10.1096/fj.05-4981com · Cited by 77 · see citing works
Molecular and Cell-Based Therapies for Protection, Rescue, and Repair of Ischemic Myocardium
Melo, L. G., Pachori, A. S., Kong, D., Gnecchi, M., Wang, K., Pratt, R. E., & Dzau, V. J. (2004) · Circulation · doi:10.1161/01.cir.0000128597.37025.00 · Cited by 77 · see citing works
Gene delivery nanoparticles to modulate angiogenesis
Kim, J., Mirando, A. C., Popel, A. S., & Green, J. J. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.11.003 · Cited by 77 · see citing works
Future Perspectives for the Treatment of Pulmonary Arterial Hypertension
Ghofrani, H. A., Barst, R. J., Benza, R. L., Champion, H. C., Fagan, K. A., Grimminger, F., Humbert, M. J. C., Simonneau, G., Stewart, D. J., Ventura, C., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.04.014 · Cited by 76 · see citing works
Insulin-like growth factor binding proteins and angiogenesis: from cancer to cardiovascular disease
Slater, T. A., Haywood, N. J., Matthews, C., Cheema, H. K., & Wheatcroft, S. B. (2019) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2019.03.005 · Cited by 74 · see citing works
Clinical translation of nitrite therapy for cardiovascular diseases
Calvert, J. W., & Lefer, D. J. (2010) · Nitric Oxide · doi:10.1016/j.niox.2009.11.001 · Cited by 72 · see citing works
Nitric Oxide and Adult Neurogenesis in Health and Disease
Estrada, C., & Murillo‐Carretero, M. (2005) · The Neuroscientist · doi:10.1177/1073858404273850 · Cited by 72 · see citing works
Tsai, A.-C., Pan, S., Liao, C.-H., Guh, J., Wang, S., Sun, H., Liu, Y.-N., Chen, C.-C., Shen, C.-C., Chang, Y.-L., et al. (2009) · Cancer Letters · doi:10.1016/j.canlet.2009.11.020 · Cited by 71 · see citing works
Redox balance dynamically regulates vascular growth and remodeling
Bir, S. C., Kolluru, G. K., Fang, K., & Kevil, C. G. (2012) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2012.05.003 · Cited by 68 · see citing works
The effect of nitric oxide surface flux on the foreign body response to subcutaneous implants
Nichols, S. P., Koh, A., Brown, N. L., Rose, M. B., Sun, B., Slomberg, D. L., Riccio, D. A., Klitzman, B., & Schoenfisch, M. H. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.05.053 · Cited by 67 · see citing works
Harding, J. L., Metz, J. M., & Reynolds, M. M. (2014) · Advanced Functional Materials · doi:10.1002/adfm.201402529 · Cited by 67 · see citing works
Effects of aging and atherosclerosis on endothelial and vascular smooth muscle function in humans
Al-Shaer, M. H., Choueiri, N. E., Correia, M., Sinkey, C. A., Barenz, T., & Haynes, W. G. (2005) · International Journal of Cardiology · doi:10.1016/j.ijcard.2005.06.002 · Cited by 67 · see citing works
Soto, R. J., Yang, L., & Schoenfisch, M. H. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b10942 · Cited by 67 · see citing works
Wilson, A., Shin, D. S., Weatherby, C., Harada, R. K., Ng, M. K., Nair, N., Kielstein, J. T., & Cooke, J. P. (2010) · Vascular Medicine · doi:10.1177/1358863x10364552 · Cited by 67 · see citing works
Self-citationWu, Y., & Meyerhoff, M. E. (2008) · Talanta · doi:10.1016/j.talanta.2007.06.022 · Cited by 65 · see citing works
Venkatesh, P. K., Pattillo, C. B., Branch, B., Hood, J., Thoma, S., Illum, S., Pardue, S., Teng, X., Patel, R. P., & Kevil, C. G. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq002 · Cited by 64 · see citing works
Isenberg, J. S., Romeo, M. J., Maxhimer, J. B., Smedley, J. V., Frazier, W. A., & Roberts, D. D. (2008) · Annals of Surgery · doi:10.1097/sla.0b013e31816c4006 · Cited by 64 · see citing works
Hsp90 as a Gatekeeper of Tumor Angiogenesis: Clinical Promise and Potential Pitfalls
Bohonowych, J. E. S., Gopal, U., & Isaacs, J. S. (2010) · Journal of Oncology · doi:10.1155/2010/412985 · Cited by 63 · see citing works
Ganguly, E., Aljunaidy, M. M., Kirschenman, R. D., Spaans, F., Morton, J. S., Phillips, T. J., Case, C. P., Cooke, C. M., & Davidge, S. T. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00562 · Cited by 60 · see citing works
Polytarchou, C., & Papadimitriou, Ε. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.01.004 · Cited by 59 · see citing works
Kou, B., Zhang, J., & Singer, D. R. J. (2008) · Microvascular Research · doi:10.1016/j.mvr.2008.08.001 · Cited by 59 · see citing works
Cao, J., Su, M., Hasan, N., Lee, J., Kwak, D., Kim, D. Y., Kim, K., Lee, E. H., Jung, J. H., & Yoo, J. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12100926 · Cited by 57 · see citing works
Expression of endothelial nitric oxide synthase in developing rat kidney
Han, K., Lim, J.-M., Kim, W., Kim, H. Y., Madsen, K., & Kim, J. (2004) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00085.2004 · Cited by 55 · see citing works
Isenberg, J. S., Roberts, D. D., & Frazier, W. A. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.158154 · Cited by 55 · see citing works
Flores, M. P. A., Fritzen, M., Reis, C. V., & Chudzinski‐Tavassi, A. M. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.03.068 · Cited by 55 · see citing works
Medicinal Plants Extracts with Antiangiogenic Activity: Where Is the Link?
Hoseinkhani, Z., Norooznezhad, F., Rastegari‐Pouyani, M., & Mansouri, K. (2020) · Advanced Pharmaceutical Bulletin · doi:10.34172/apb.2020.045 · Cited by 54 · see citing works
Raźny, U., Kieć‐Wilk, B., Wątor, Ł., Polus, A., Dyduch, G., Solnica, B., Malecki, M. T., Tomaszewska, R., Cooke, J. P., & Dembinska-Kiec, A. (2011) · Cardiovascular Diabetology · doi:10.1186/1475-2840-10-68 · Cited by 53 · see citing works
Self-citationMalone‐Povolny, M. J., & Schoenfisch, M. H. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b19236 · Cited by 54 · see citing works
Thompson, V. C., Morris, T. G. W., Cochrane, D. R., Cavanagh, J., Wafa, L. A., Hamilton, T., Wang, S., Fazli, L., Gleave, M. E., & Nelson, C. C. (2006) · The Prostate · doi:10.1002/pros.20423 · Cited by 54 · see citing works
Supplemental Conditionally Essential Nutrients in Cardiovascular Disease Therapy
Kendler, B. S. (2006) · The Journal of Cardiovascular Nursing · doi:10.1097/00005082-200601000-00004 · Cited by 54 · see citing works
Kasoju, N., Bhonde, R. R., & Bora, U. (2009) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.196 · Cited by 53 · see citing works
Defective Lung Vascular Development in Endothelial Nitric Oxide Synthase-Deficient Mice
Han, R. N. N., & STEWART, D. (2005) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2005.11.004 · Cited by 53 · see citing works
The ADMA/DDAH Pathway Regulates VEGF-Mediated Angiogenesis
Fiedler, L. R., Bachetti, T., LEIPER, J. M., Zachary, I. C., Chen, L., Renné, T., & Wójciak‐Stothard, B. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.194035 · Cited by 52 · see citing works
Arginine deprivation therapy for malignant melanoma
Kim, K., Yoon, Y., Frankel, A. E., Feun, & Ekmekcioglu (2012) · Clinical Pharmacology Advances and Applications · doi:10.2147/cpaa.s37350 · Cited by 50 · see citing works
Amin, A. H., Choi, S. K., Galán, M., Kassan, M., Partyka, M., Kadowitz, P. J., Henrion, D., Trebak, M., Belmadani, S., & Matrougui, K. (2011) · The Journal of Pathology · doi:10.1002/path.3960 · Cited by 49 · see citing works
Uruno, A., Sugawara, A., Kanatsuka, H., Arima, S., Taniyama, Y., Kudo, M., Takeuchi, K., & Ito, S. (2004) · Hypertension Research · doi:10.1291/hypres.27.887 · Cited by 49 · see citing works
Pullamsetti, S. S., Savai, R., Schaefer, M. B., Wilhelm, J., Ghofrani, H. A., Weißmann, N., Schudt, C., Fleming, I., Mayer, K., LEIPER, J. M., et al. (2011) · Circulation · doi:10.1161/circulationaha.110.941484 · Cited by 48 · see citing works
Paroni, R. C., Fermo, I., Fiorina, P., & Cighetti, G. (2005) · Amino Acids · doi:10.1007/s00726-005-0191-z · Cited by 48 · see citing works
Dahl, J., Li, J., Bring, D. K. ‐., Renström, P. A. F. H., & Ackermann, P. W. (2007) · Journal of Orthopaedic Research® · doi:10.1002/jor.20390 · Cited by 48 · see citing works
Nitric Oxide-Releasing Electrospun Polymer Microfibers
Coneski, P. N., Nash, J. A., & Schoenfisch, M. H. (2011) · ACS Applied Materials & Interfaces · doi:10.1021/am101010e · Cited by 47 · see citing works
Liu, J., Pei, T., Mu, J., Zheng, C., Chen, X., Huang, C., Fu, Y., Liang, Z., & Wang, Y. (2016) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2016/9025036 · Cited by 47 · see citing works
Li, S., Pan, J., Hua, X., Liu, H., Shen, S., Liu, J., Li, B., Tao, B., Ge, X., Wang, X., et al. (2014) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12182 · Cited by 46 · see citing works
- Authors
- Cooke, J. P.
- Affiliations
- Stanford Medicine (US)
- Corresponding author
- Cooke, John P.
- ORCID
- Cooke, John P.
- Venue
- Atherosclerosis Supplements
- Publisher
- Elsevier BV
- Published
- 2003-12
- Volume
- 4
- Issue
- 4
- Pages
- 53-60
- ISSN
- 1567-5688 (ISSN-L)
- OpenAlex
- W2075124894
- Cited by
- 266
- References
- 78
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 4 · 2023: 5 · 2022: 9 · 2021: 2 · 2020: 8 · 2019: 8 · 2018: 9 · 2017: 8 · 2016: 13 · 2015: 13 · 2014: 14 · 2013: 15 · 2012: 17
- FWCI
- 2.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Atherosclerosis Supplements (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1z01hl000204-29)
- National Institute on Aging (P01 AG18784, P01AG018784)
- National Heart, Lung, and Blood Institute (R01 HL-63685, R01HL063685)
- National Institute of Allergy and Infectious Diseases (P01AI050153, P01AI50153)
- National Center for Complementary and Integrative Health (R01 AT/HL00204)
- Topics
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Eicosanoids and Hypertension Pharmacology
- Keywords
- nitric oxide, angiogenesis, endothelial cells, nitric oxide synthase, asymmetric dimethylarginine, endothelial cell migration, endothelial cell proliferation, endothelial cell survival, extracellular matrix, statins
- MeSH terms
- Arginine, Cardiovascular Diseases, Cell Movement, Cell Survival, Endothelium, Vascular, Enzyme Inhibitors, Humans, Nitric Oxide, Angiogenesis Inhibitors, Endothelial Cells
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