Hypertension and sleep: Overview of a tight relationship
Abstract
Autonomic cardiovascular control changes across sleep stages. Thus, blood pressure (BP), heart rate and peripheral vascular resistance progressively decrease in non-rapid eye movement sleep. Any deterioration in sleep quality or quantity may be associated with an increase in nocturnal BP which could participate in the development or poor control of hypertension. In the present report, sleep problems/disorders, which impact either the quality or quantity of sleep, are reviewed for their interaction with BP regulation and their potential association with prevalent or incident hypertension. Obstructive sleep apnea syndrome, sleep duration/deprivation, insomnia, restless legs syndrome and narcolepsy are successively reviewed. Obstructive sleep apnea is clearly associated with the development of hypertension that is only slightly reduced by continuous positive airway pressure treatment. Shorter and longer sleep durations are associated with prevalent or incident hypertension but age, gender, environmental exposures and ethnic differences are clear confounders. Insomnia with objective short sleep duration, restless legs syndrome and narcolepsy may impact BP control, needing additional studies to establish their impact in the development of permanent hypertension. Addressing sleep disorders or sleep habits seems a relevant issue when considering the risk of developing hypertension or the control of pre-existent hypertension. Combined sleep problems may have potential synergistic deleterious effects.
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Poor sleep quality is not the result of just obstructive sleep apnea but a host of sleep disorders, including restless leg syndrome and insomnia of various causes.
“Poor sleep quality is not the result of just OSA but a host of sleep disorders, including restless leg syndrome and insomnia of various causes.251”
From Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association (2018) · cites this paper as [251]
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- Authors
- Pepin, J.-L., Borel, A.-L., Tamisier, R., Baguet, J.-P., Levy, P., & Dauvilliers, Y.
- Affiliations
- Inserm (FR)
- Centre Hospitalier Universitaire de Grenoble (FR)
- Venue
- Sleep Medicine Reviews
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 18
- Issue
- 6
- Pages
- 509-519
- ISSN
- 1087-0792 (ISSN-L)
- OpenAlex
- W2156027352
- Cited by
- 245
- References
- 110
- Citations by year
- 2026: 8 · 2025: 24 · 2024: 29 · 2023: 9 · 2022: 23 · 2021: 23 · 2020: 21 · 2019: 40 · 2018: 18 · 2017: 17 · 2016: 16 · 2015: 14 · 2014: 3
- FWCI
- 1.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sleep Medicine Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- hypertension, sleep disorders, blood pressure regulation, obstructive sleep apnea, sleep duration, sleep deprivation, insomnia, restless legs syndrome, narcolepsy, continuous positive airway pressure, autonomic cardiovascular control, nocturnal blood pressure, sleep quality
- MeSH terms
- Humans, Hypertension, Sleep Initiation and Maintenance Disorders, Narcolepsy, Restless Legs Syndrome, Sleep, Sleep Stages, Sleep Apnea, Obstructive, Nocturnal Myoclonus Syndrome
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