Social effects of oxytocin in humans: context and person matter

In the citing paper

“The trust-enhancing effect (Baumgartner, Heinrichs, Vonlanthen, Fischbacher, & Fehr, 2008;Van IJzendoorn & Bakermans-Kranenburg, 2012) may be stronger if a positive relationship already exists between the supportive other and the support recipient (Bartz et al., 2011).”

In the citing paper

“More and more research suggests that OT effects are context dependent (see [29] for a review).”

In the citing paper

“More recently, attention has turned to its role in regulating complex social behavior, including parental care, social bonding and social cognition in general (1–6).”

In the citing paper

“Since oxytocin can strengthen the encoding of positive social stimuli to make them more salient, it might facilitate interpersonal intimacy by making the encoding of positive social cues more rewarding and memorable [69].”

In the citing paper

“And oxytocin seems to improve empathic accuracy only in less-socially proficient individuals, whereas it has no effect for those who are already well-attuned to social information [69].”

In the citing paper

“As parallel data on OT effects in both men and women are still rare and, in part, conflicting (for an overview, see Bartz et al., 2011), it is particularly important to investigate both sexes within the same research design.”

In the citing paper

“Thus, in line with Bartz et al. (2011) andMcCall andSinger (2012), in our study, OT might have driven quiescence in women and social salience and approach behavior in men.”

In the citing paper

“the majority of IN-OT studies do not yield a main IN-OT treatment effects.”

In the citing paper

“Through the literature, more and more findings suggest that IN-OT influences behaviors by interacting with several moderators (for a review see (19)).”

In the citing paper

“These data substantially support the concept that the behavioral effects of OXT are moderated by contextual factors and personal characteristics such as relationship status (Bartz et al., 2011) and provide the first direct evidence for a behavior-modifying role of OXT in helping to maintain monogamous pair-bonds in humans.”

In the citing paper

“There are also human studies showing that the behavioral effects of AVP and OXT depend on social contextual factors (Declerck et al., 2010; Bartz et al., 2011; Rilling et al., 2012; Olff et al., 2013).”

In the citing paper

“Indeed, endogenous oxytocin may be an important regulator and a biomarker of subjects' social motivation toward, or perception of, a given social context (Bartz et al., 2011; Macdonald and Feifel, 2013).”

In the citing paper

“Of these studies, the focus has been almost exclusively on determining what oxytocin does, to whom and in what contexts (Bartz et al., 2011; Olff et al., 2013; Veening and Olivier, 2013 for reviews).”

In the citing paper

“Recently, however, strong indicators have emerged that such beneficial effects of oxytocin may occur only under specific social circumstances (Bartz et al., 2011; Olff et al., 2013).”

In the citing paper

“In addition, the effects that oxytocin has and what triggers oxytocin release in a given social context can both vary depending on individual differences such as sex, age, early experience, psychiatric or psychological health (effects of oxytocin: Bartz et al., 2011; Macdonald and Feifel, 2013; Olff et al., 2013; release of oxytocin: Sanders et al., 1990; Turner et al., 1999).”

In the citing paper

“Within-species studies are already demonstrating considerable variation between individuals on the effects that oxytocin has on social behavior, as noted above (for reviews see Bartz et al., 2011; Olff et al., 2013).”

In the citing paper

“However, a number of studies in healthy people, as well as in patients with psychological or psychiatric disorders show that administration of oxytocin leads to negative not positive social effects (Epperson et al., 1996; Bartz et al., 2011; Feifel, 2011; Mah et al., 2012), suggesting that exogenous oxytocin does not always lead to increased affiliation.”

In the citing paper

“Likewise, determining how applied doses may relate to endogenous oxytocin levels and their effects has not been addressable, partly because few studies measure endogenous oxytocin levels in conjunction with oxytocin administration (review: Bartz et al., 2011; Olff et al., 2013).”

In the citing paper

“That oxytocin release may depend more on an individuals' social perception of an interaction than on the properties of the interaction itself mirrors other studies on human and non-human primates which suggest that inhaled oxytocin changes individuals' perception or motivation toward a social context (Chang et al., 2012; Parr et al., 2013, for reviews see: Bartz et al., 2011; Olff et al., 2013).”

In the citing paper

“Studies using exogenous oxytocin have highlighted how a possible effect of oxytocin is to change individuals' social motivations or perceptions of a current social context, such that individuals that inhale oxytocin compared with those that do not, become more affiliative, attentive, prosocial or empathetic to the same social stimuli (e.g., Bartz et al., 2011; Chang et al., 2012; Parr et al., 2013”

In the citing paper

“Additionally, inhaled OT increases sensitivity to the social information of co-players in a social dilemma game (Declerck et al., 2010, 2013; Mikolajczak et al., 2010; Bartz et al., 2011;)”