The DOI matches its Crossref record; 114 of the 117 references it cites were found in a registry or an index.
Social effects of oxytocin in humans: context and person matter
Abstract
Building on animal research, the past decade has witnessed a surge of interest in the effects of oxytocin on social cognition and prosocial behavior in humans. This work has generated considerable excitement about identifying the neurochemical underpinnings of sociality in humans, and discovering compounds to treat social functioning deficits. Inspection of the literature, however, reveals that the effects of oxytocin in the social domain are often weak and/or inconsistent. We propose that this literature can be informed by an interactionist approach in which the effects of oxytocin are constrained by features of situations and/or individuals. We show how this approach can improve understanding of extant research, suggest novel mechanisms through which oxytocin might operate, and refine predictions about oxytocin pharmacotherapy.
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In the citing paper
“The trust-enhancing effect (Baumgartner, Heinrichs, Vonlanthen, Fischbacher, & Fehr, 2008;Van IJzendoorn & Bakermans-Kranenburg, 2012) may be stronger if a positive relationship already exists between the supportive other and the support recipient (Bartz et al., 2011).”
From Oxytocin enhances the pain‐relieving effects of social support in romantic couples (2019) · cites this paper as Bartz et al., 2011
In the citing paper
“More and more research suggests that OT effects are context dependent (see [29] for a review).”
From Failed Replication of Oxytocin Effects on Trust: The Envelope Task Case (2015) · cites this paper as [29]
In the citing paper
“More recently, attention has turned to its role in regulating complex social behavior, including parental care, social bonding and social cognition in general (1–6).”
From Statistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies (2016) · cites this paper as [1]
In the citing paper
“Since oxytocin can strengthen the encoding of positive social stimuli to make them more salient, it might facilitate interpersonal intimacy by making the encoding of positive social cues more rewarding and memorable [69].”
From Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations (2013) · cites this paper as [69]
In the citing paper
“And oxytocin seems to improve empathic accuracy only in less-socially proficient individuals, whereas it has no effect for those who are already well-attuned to social information [69].”
From Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations (2013) · cites this paper as [69]
In the citing paper
“As parallel data on OT effects in both men and women are still rare and, in part, conflicting (for an overview, see Bartz et al., 2011), it is particularly important to investigate both sexes within the same research design.”
From Sex-specific effects of intranasal oxytocin on autonomic nervous system and emotional responses to couple conflict (2013) · cites this paper as Bartz et al., 2011
In the citing paper
“Thus, in line with Bartz et al. (2011) andMcCall andSinger (2012), in our study, OT might have driven quiescence in women and social salience and approach behavior in men.”
From Sex-specific effects of intranasal oxytocin on autonomic nervous system and emotional responses to couple conflict (2013) · cites this paper as Bartz et al., 2011
In the citing paper
“the majority of IN-OT studies do not yield a main IN-OT treatment effects.”
From Is there a Publication Bias in Behavioural Intranasal Oxytocin Research on Humans? Opening the File Drawer of One Laboratory (2016) · cites this paper as [19]
In the citing paper
“Through the literature, more and more findings suggest that IN-OT influences behaviors by interacting with several moderators (for a review see (19)).”
From Is there a Publication Bias in Behavioural Intranasal Oxytocin Research on Humans? Opening the File Drawer of One Laboratory (2016) · cites this paper as [19]
In the citing paper
“These data substantially support the concept that the behavioral effects of OXT are moderated by contextual factors and personal characteristics such as relationship status (Bartz et al., 2011) and provide the first direct evidence for a behavior-modifying role of OXT in helping to maintain monogamous pair-bonds in humans.”
From Oxytocin Modulates Social Distance between Males and Females (2012) · cites this paper as Bartz et al., 2011
In the citing paper
“There are also human studies showing that the behavioral effects of AVP and OXT depend on social contextual factors (Declerck et al., 2010; Bartz et al., 2011; Rilling et al., 2012; Olff et al., 2013).”
From Sex-specific modulation of juvenile social play behavior by vasopressin and oxytocin depends on social context (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“Indeed, endogenous oxytocin may be an important regulator and a biomarker of subjects' social motivation toward, or perception of, a given social context (Bartz et al., 2011; Macdonald and Feifel, 2013).”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“Of these studies, the focus has been almost exclusively on determining what oxytocin does, to whom and in what contexts (Bartz et al., 2011; Olff et al., 2013; Veening and Olivier, 2013 for reviews).”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“Recently, however, strong indicators have emerged that such beneficial effects of oxytocin may occur only under specific social circumstances (Bartz et al., 2011; Olff et al., 2013).”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“In addition, the effects that oxytocin has and what triggers oxytocin release in a given social context can both vary depending on individual differences such as sex, age, early experience, psychiatric or psychological health (effects of oxytocin: Bartz et al., 2011; Macdonald and Feifel, 2013; Olff et al., 2013; release of oxytocin: Sanders et al., 1990; Turner et al., 1999).”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“Within-species studies are already demonstrating considerable variation between individuals on the effects that oxytocin has on social behavior, as noted above (for reviews see Bartz et al., 2011; Olff et al., 2013).”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“However, a number of studies in healthy people, as well as in patients with psychological or psychiatric disorders show that administration of oxytocin leads to negative not positive social effects (Epperson et al., 1996; Bartz et al., 2011; Feifel, 2011; Mah et al., 2012), suggesting that exogenous oxytocin does not always lead to increased affiliation.”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“Likewise, determining how applied doses may relate to endogenous oxytocin levels and their effects has not been addressable, partly because few studies measure endogenous oxytocin levels in conjunction with oxytocin administration (review: Bartz et al., 2011; Olff et al., 2013).”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“That oxytocin release may depend more on an individuals' social perception of an interaction than on the properties of the interaction itself mirrors other studies on human and non-human primates which suggest that inhaled oxytocin changes individuals' perception or motivation toward a social context (Chang et al., 2012; Parr et al., 2013, for reviews see: Bartz et al., 2011; Olff et al., 2013).”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“Studies using exogenous oxytocin have highlighted how a possible effect of oxytocin is to change individuals' social motivations or perceptions of a current social context, such that individuals that inhale oxytocin compared with those that do not, become more affiliative, attentive, prosocial or empathetic to the same social stimuli (e.g., Bartz et al., 2011; Chang et al., 2012; Parr et al., 2013”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Bartz et al., 2011
In the citing paper
“Additionally, inhaled OT increases sensitivity to the social information of co-players in a social dilemma game (Declerck et al., 2010, 2013; Mikolajczak et al., 2010; Bartz et al., 2011;)”
From Oxytocin promotes altruistic punishment (2017) · cites this paper as Bartz et al., 2011
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“…et al.) or differential interpretations due to interindividual factors (i.e. sex in study of Kubzansky et al.; attachment style in study of Bartz et al.; presence of depressive symptoms in study of Ellenbogen & Cardoso), further reinforcing a more nuanced view of oxytocin (Bartz et al., 2011a).”
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“It has been proposed, for example, that OT might affect complex behaviors by regulating lowlevel processes such as attention to social cues (Averbeck, 2010; Bartz et al., 2011; Churchland & Winkielman, 2012; Heinrichs, Baumgartner, Kirschbaum, & Ehlert, 2003; Heinrichs & Domes, 2008; Weisman & Feldman, 2013), reducing…”
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“However, there also has been evidence that the effects of oxytocin are context-dependent, and under some conditions, oxytocin can lead to negative relational behaviors such as gloating (e.g., Bartz et al., 2011; Grillon et al., 2013; Olff et al., 2013; Shamay-Tsoory et al., 2009).”
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“Traditionally known for their roles in reproduction and homeostasis in a variety of species (Carter et al. 2008), more recent studies have shown their pivotal roles in different manifestations of human prosocial behavior (Bartz et al. 2011, Domes et al. 2007b, Kosfeld et al. 2005).”
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“Therapeutic uses of oxytocin are currently being investigated in other neuropsychiatric disorders associated with poor social cognition, including ASD, OCD and schizophrenia e.g. (Bartz et al., 2011; Macdonald and Feifel, 2013).”
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“previously, the exact effect OT has on amygdala activation is likely to be task-dependant (Bartz et al., 2011).”
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“The finding that acute effects of oxytocin were moderated by individual differences in empathic concern fits with Bartz et al. (2011) who concluded that effects of oxytocin on social cognition and behavior depend on the individual’s chronic predispositions and personality traits.”
Insular cortex mediates approach and avoidance responses to social affective stimuli
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“Like social behavior itself, the effects of OT administration on social decision-making are sensitive to situational and interpersonal factors, with OT sometimes producing prosocial effects and at other times anti-social effects 46 ; both were observed after insular OT administration.”
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“Endogenous oxytocin levels appear to co-vary with social cognitive function at all levels of information processing in humans and other mammals, with similar observed effects after administration of exogenous oxytocin (Bartz et al., 2011).”
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“Social cognition is thus biased towards positive social cues by oxytocin, although the story is by no means simple (Bartz et al., 2011).”
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“Robert J. Sternberg 1”
BackgroundMethodBales, K. L., Perkeybile, A. M., Conley, O. G., Lee, M. H., Guoynes, C. D., Downing, G. M., Yun, C. R., Solomon, M., Jacob, S., & Mendoza, S. P. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.08.025 · Cited by 265
“Context may be important for long-term effects of OT (for example, pairing OT administration with specific environments or social learning tasks) to generate specific effects in humans and animals (81).”
Reward system dysfunction in autism spectrum disorders
Kohls, G., Schulte-Rüther, M., Nehrkorn, B., Müller, K., Fink, G. R., Kamp-Becker, I., Herpertz-Dahlmann, B., Schultz, R. T., & Konrad, K. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nss033 · Cited by 259
“An increased understanding of the biological mechanisms causing social deficits in ASD can be used to develop therapeutic interventions where, for instance, pharmacological agents (like oxytocin) support social learning via increased reward-based motivation (Bartz et al., 2011).”
BackgroundQuintana, D. S., Lischke, A., Grace, S., Scheele, D., Ma, Y., & Becker, B. (2021) · Molecular Psychiatry · doi:10.1038/s41380-020-00864-7 · Cited by 263
“, envy [15], gloating [15], or aggression [16, 17]), the mediating effects of oxytocin-induced changes in social stimulus processing on social behavior are far more complex than initially thought [18].”
BackgroundApter-Levy, Y., Feldman, M., Vakart, A., Ebstein, R. P., & Feldman, R. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12121597 · Cited by 271
“Similarly, oxytocin is linked with empathy, theory of mind, and prosocial orientation (13), pointing to its role in the general capacity for collaborative engagement with the social world (6).”
BackgroundNasal oxytocin for social deficits in childhood autism: A randomized controlled trial
Dadds, M. R., MacDonald, E., Cauchi, A., Williams, K., Levy, F., & Brennan, J. (2014) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-013-1899-3 · Cited by 250
“These and the current data are consistent with a growing awareness that the therapeutic effects of oxytocin may be more specific and contextually grounded than previously thought (Bartz et al. 2011; Guastella and MacLeod 2012).”
ResultSocial Support and Physical Health: Models, Mechanisms, and Opportunities
Uchino, B. N., Bowen, K. S., de Grey, R. K., Mikel, J., & Fisher, E. B. (2018) · Springer eBooks · doi:10.1007/978-0-387-93826-4_12 · Cited by 289
Chang, S. W. C., Barter, J. W., Ebitz, R. B., Watson, K. K., & Platt, M. L. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114621109 · Cited by 252
“OT can both promote cooperation and increase out-group bias depending on behavioral context (16, 17, 39).”
BackgroundOxytocin facilitates protective responses to aversive social stimuli in males
Striepens, N., Scheele, D., Kendrick, K. M., Becker, B., Schäfer, L., Schwalba, K., Reul, J., Maier, W., & Hurlemann, R. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208852109 · Cited by 242
“Whether these mechanisms quintessentially yield positive or negative social outcomes may vary depending on contextual or person-specific characteristics (21).”
BackgroundThe Social Modulation of Pain: Others as Predictive Signals of Salience – a Systematic Review
Krahé, C., Springer, A., Weinman, J. A., & Fotopoulou, A. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00386 · Cited by 245
“To review such heterogeneous data, and motivated by interactionist accounts of social cognition (e.g., Bartz et al., 2011), we drew a distinction between studies in which social partners were perceived by the participants to be active or to possess possibility for action (see The Social Partner’s…”
BackgroundCarré, J. M., & Olmstead, N. A. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.11.029 · Cited by 262
“Notably, a surge of research examining the effect of oxytocin administration on human behavior finds that individual difference factors and social context play an important role in moderating the effect of this hormone on cognitive and behavioral processes (see Bartz et al., 2011 for review).”
Parental Reflective Functioning: Theory, Research, and Clinical Applications
Luyten, P., Nijssens, L., Fonagy, P., & Mayes, L. C. (2017) · The Psychoanalytic Study of the Child · doi:10.1080/00797308.2016.1277901 · Cited by 283
Guastella, A. J., & Hickie, I. B. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.06.028 · Cited by 223
“Oxytocin effects can be sensitive to social contexts, even to increase defensive tendencies (62,63), and individual differences moderate effects (64,65).”
Weisman, O., Zagoory-Sharon, O., & Feldman, R. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.011 · Cited by 240
“The discovery that intranasal administration of neuropeptides an reach the human central nervous system (17) has led to extant esearch demonstrating the involvement of OT in a host of social ehaviors and cognitions (18).”
Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity
Spengler, F. B., Schultz, J., Scheele, D., Essel, M., Maier, W., Heinrichs, M., & Hurlemann, R. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.04.015 · Cited by 229
“More generally, the person-dependent OXT effects reported here are well in line with previous studies (41,60,62), although the direction of the moderation effect may be domain specific and may vary with baseline responses.”
BackgroundResultClinical and neural effects of six-week administration of oxytocin on core symptoms of autism
Watanabe, T., Kuroda, M., Kuwabara, H., Aoki, Y., Iwashiro, N., Tatsunobu, N., Takao, H., Nippashi, Y., Kawakubo, Y., Kunimatsu, A., et al. (2015) · Brain · doi:10.1093/brain/awv249 · Cited by 222
Forkey, H. C., Szilagyi, M. A., Kelly, E. T., Duffee, J. H., Springer, S. H., Fortin, K., Jones, V. F., Greiner, M. B. V., Ochs, T. J., Partap, A. N., et al. (2021) · PEDIATRICS · doi:10.1542/peds.2021-052580 · Cited by 247
Sense of relatedness boosts engagement, achievement, and well-being: A latent growth model study
King, R. B. (2015) · Contemporary Educational Psychology · doi:10.1016/j.cedpsych.2015.04.002 · Cited by 228
Atzil, S., Hendler, T., Zagoory-Sharon, O., Winetraub, Y., & Feldman, R. (2012) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2012.06.008 · Cited by 225
Groppe, S. E., Gossen, A., Rademacher, L., Hahn, A., Westphal, L., Gründer, G., & Spreckelmeyer, K. N. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.12.023 · Cited by 218
“(31) pointed out that the effects of oxytocin seem to be highly person-dependent.”
BackgroundTone, E. B., & Tully, E. C. (2014) · Development and Psychopathology · doi:10.1017/s0954579414001199 · Cited by 253
Oxytocin promotes social bonding in dogs
Romero, T., Nagasawa, M., Mogi, K., Hasegawa, T., & Kikusui, T. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1322868111 · Cited by 233
“Despite these findings and theories, few studies have measured endogenous OT levels in conjunction with OT administration (12).”
BackgroundResultThe neurochemistry and social flow of singing: bonding and oxytocin
Keeler, J. R., Roth, E. A., Neuser, B. L., Spitsbergen, J. M., Waters, D. J. M., & Vianney, J.-M. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00518 · Cited by 220
“Depending on the context and the individual, it is hypothesized that oxytocin may elicit positive or negative social emotions (Bartz et al., 2011).”
The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies
Modi, M. E., & Young, L. J. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.010 · Cited by 218
“The “fine tuning” function of OT corresponds to the often intact pedantic emotion recognition among individuals with social deficits despite impairments in the context of a complex social interaction (Bartz et al., 2011).”
BackgroundOxytocin and social motivation
Gordon, I., Martin, C., Feldman, R., & Leckman, J. F. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.07.007 · Cited by 211
“…context during the course of development There are several comprehensive reviews on this topic that focus either on animal studies, human studies, or both (Barrett and Fleming, 2011; Bartz et al., 2011; Bos et al., 2011; Goodson and Thompson, 2010; Heinrichs et al., 2009; Ross and Young, 2009).”
InfluentialBertsch, K., Gamer, M., Schmidt, B., Schmidinger, I., Walther, S., Kästel, T., Schnell, K., Büchel, C., Domes, G., & Herpertz, S. C. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.13020263 · Cited by 214
Dodhia, S., Hosanagar, A., Fitzgerald, D. A., Labuschagne, I., Wood, A. G., Nathan, P. J., & Phan, K. L. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.53 · Cited by 209
Oxytocin receptor genetic variation promotes human trust behavior
Krueger, F., Parasuraman, R., Iyengar, V., Thornburg, M., Weel, J., Lin, M., Clarke, E., McCabe, K., & Lipsky, R. H. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00004 · Cited by 207
“Frontiers in Human Neuroscience www.frontiersin.org February 2012 | Volume 6 | Article 4 | 4 crucial mediator in the regulation of complex social cognition and behavior (for reviews, see Bartz et al., 2011; Kemp and Guastella, 2011; Meyer-Lindenberg et al., 2011).”
Deconstructing sociality, social evolution and relevant nonapeptide functions
Goodson, J. L. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.12.005 · Cited by 206
“…by an increasingly large number of studies (Ferris and Delville, 1994; Thompson and Walton, 2004; Thompson et al., 2006; De Dreu et al., 2010, 2011; Bartz et al., 2011a,b), as summarized in Section 1, and it is quite clear that the relationships between nonapeptides and behavior cannot be…”
BackgroundPaloyelis, Y., Doyle, O. M., Zelaya, F. O., Maltezos, S., Williams, S. C., Fotopoulou, A., & Howard, M. A. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.10.005 · Cited by 187
“The power of arterial spin labeling to quantify the effects of IN-OT on brain physiology renders it a promising, noninvasive, in vivo method to investigate the impact of genetic (9,143), epigenetic (126), social-environmental (40), and contextual (144) factors on the baseline function of the OT system.”
Bolis, D., Balsters, J., Wenderoth, N., Becchio, C., & Schilbach, L. (2017) · Psychopathology · doi:10.1159/000484353 · Cited by 204
Ellingsen, D., Leknes, S., Løseth, G. E., Wessberg, J., & Olausson, H. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01986 · Cited by 214
“Similar to the effects of MOR system manipulations, the behavioral effects of oxytocin administration seem to vary across contexts and affective states (Bartz et al., 2011).”
BackgroundOxytocin, the peptide that bonds the sexes also divides them
Gao, S., Becker, B., Luo, L., Geng, Y., Zhao, W., Yin, Y., Hu, J., Gao, Z., Gong, Q., Hurlemann, R., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1602620113 · Cited by 186
“, “fight or flight”) individuals in their environment with negative social attributes (3, 4, 34), and perhaps also by reducing partner conflict (6).”
BackgroundInfluentialKing, L. B., Walum, H., Inoue, K., Eyrich, N. W., & Young, L. J. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.12.008 · Cited by 191
“Some individuals have heterogeneous responses to OXT (22,23), which may involve interaction with OXTR genetic polymorphisms (24–27).”
Social “wanting” dysfunction in autism: neurobiological underpinnings and treatment implications
Kohls, G., Chevallier, C., Troiani, V., & Schultz, R. T. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-10 · Cited by 197
“Oxytocin is best known for its contribution to numerous social functions in humans and animals, including social recognition, species-specific interactions, attachment, and other pro-social behavior [120,149-151].”
BackgroundInfluentialTackling Taboo Topics: A Review of the Three M s in Working Women’s Lives
Grandey, A. A., Gabriel, A. S., & King, E. B. (2019) · Journal of Management · doi:10.1177/0149206319857144 · Cited by 198
Meta-analysis of the effects of intranasal oxytocin on interpretation and expression of emotions
Leppanen, J., Ng, K. W., Tchanturia, K., & Treasure, J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.04.010 · Cited by 188
“Recently there has been increasing interest in translating these findings into humans and the effects of intranasal oxytocin on socialemotional function has been widely studied (Bakermans-Kranenburg and van Ijzendoorn, 2013; Bartz et al., 2011; Guastella and MacLeod, 2012; Shahrestani et al., 2013; van Ijzendoorn and…”
Testosterone inhibits trust but promotes reciprocity
Boksem, M. A. S., Mehta, P. H., Van den Bergh, B., van Son, V., Trautmann, S. T., Roelofs, K., Smidts, A., & Sanfey, A. G. (2013) · Psychological Science · doi:10.1177/0956797613495063 · Cited by 191
“…a motivation to affiliate or dominate) that alter the basic processing of social challenges, which in turn could produce a wide variety of behavioral effects that could be qualified as either anti- or prosocial, depending on the situational context (see also Bartz et al., 2011; Bos et al., 2012).”
Gossen, A., Hahn, A., Westphal, L., Prinz, S., Schultz, R. T., Gründer, G., & Spreckelmeyer, K. N. (2012) · Neuropeptides · doi:10.1016/j.npep.2012.07.001 · Cited by 189
Crockford, C., Deschner, T., Ziegler, T. E., & Wittig, R. M. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00068 · Cited by 187
Oxytocin enhances inter-brain synchrony during social coordination in male adults
Mu, Y., Guo, C., & Han, S. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw106 · Cited by 177
“…oscillation; oxytocin; social coordination 25 Introduction The neuropeptide oxytocin (OT) plays a key role in human social interactions by modulating the underlying cognitive and neural processes (Bartz et al., 2011; Meyer-Lindenberg et al., 2011; Hurlemann and Scheele, 2015; Ma et al., 2016).”
BackgroundReduced plasma oxytocin levels in female patients with borderline personality disorder
Bertsch, K., Schmidinger, I., Neumann, I. D., & Herpertz, S. C. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.11.013 · Cited by 189
“However, the findings of recent (meta-analytic) reviews suggest that the relationship between oxytocin and social cognition is more complex and might be strongly influenced by contextual effects, such as task difficulty, and individual differences, such as gender or social abilities (Bartz et al., 2011; Van IJendoorn…”
BackgroundInfluentialOxytocin improves behavioural and neural deficits in inferring others’ social emotions in autism
Aoki, Y., Yahata, N., Watanabe, T., Takano, Y., Kawakubo, Y., Kuwabara, H., Iwashiro, N., Natsubori, T., Inoue, H., Suga, M., et al. (2014) · Brain · doi:10.1093/brain/awu231 · Cited by 187
“…College London 31 PUBLICATIONS 269 CITATIONS SEE PROFILE Tatsunobu Natsubori The University of Tokyo 21 PUBLICATIONS 101 CITATIONS SEE PROFILE Wataru Gonoi The University of Tokyo 35 PUBLICATIONS 175 CITATIONS SEE PROFILE Available from: Takamitsu Watanabe Retrieved on: 24 June 2015 BRAIN”
BackgroundInformal Caregiving: A Reappraisal of Effects on Caregivers
Brown, R. M., & Brown, S. L. (2014) · Social Issues and Policy Review · doi:10.1111/sipr.12002 · Cited by 209
“Human studies also show a relationship between (intranasal administration of) oxytocin and elements of prosocial behavior (e.g., empathy, trust, generosity), but results to date have been variable and context-specific (Bartz et al., 2011).”
Brown, S. L., & Brown, R. M. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.004 · Cited by 212
Ramsey, M. A., & Gentzler, A. L. (2015) · Developmental Review · doi:10.1016/j.dr.2015.01.003 · Cited by 185
Luyten, P., Campbell, C., & Fonagy, P. (2020) · Journal of Personality · doi:10.1111/jopy.12483 · Cited by 181
Watanabe, T., Abe, O., Kuwabara, H., Yahata, N., Takano, Y., Iwashiro, N., Natsubori, T., Aoki, Y., Takao, H., Kawakubo, Y., et al. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.3181 · Cited by 183
Dopamine in the medial amygdala network mediates human bonding
Atzil, S., Touroutoglou, A., Rudy, T., Salcedo, S., Feldman, R., Hooker, J. M., Dickerson, B. C., Catana, C., & Barrett, L. F. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1612233114 · Cited by 182
Huggable communication medium decreases cortisol levels
Sumioka, H., Nakae, A., Kanai, R., & Ishiguro, H. (2013) · Scientific Reports · doi:10.1038/srep03034 · Cited by 180
MacDonald, K., & Feifel, D. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00035 · Cited by 181
“AUGMENTATION: CAN OXYTOCIN TREAT ON ITS OWN OR IS IT BETTER SUITED TO AUGMENT OTHER ESTABLISHED TREATMENTS? The discovery of the molecular mechanisms wherein experience becomes written in the nervous system (Kandel and Squire, 1999), and the growing understanding that OT’s effects vary significantly based on context (…”
BackgroundWigton, R., Radua, J., Allen, P., Averbeck, B., Meyer-Lindenberg, A., McGuire, P., Shergill, S. S., & Fusar-Poli, P. (2015) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.130289 · Cited by 179
Smearman, E. L., Almli, L. M., Conneely, K. N., Brody, G. H., Sales, J. M., Bradley, B., Ressler, K. J., & Smith, A. K. (2016) · Child Development · doi:10.1111/cdev.12493 · Cited by 173
“Oxytocin is a neurohormone involved in social behaviors and the development of bonds (Bartz, Zaki, Bolger, & Ochsner, 2011; Insel & Young, 2001).”
Metadata
- Authors
- Bartz, J. A., Zaki, J., Bolger, N., & Ochsner, K. N.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Harvard University (US)
- Columbia University (US)
- Corresponding author
- Bartz, Jennifer A.
- Venue
- Trends in Cognitive Sciences
- Publisher
- Elsevier BV
- Published
- 2011-06
- Volume
- 15
- Issue
- 7
- Pages
- 301-9
- ISSN
- 1364-6613 (ISSN-L)
- OpenAlex
- W2061226698
- Cited by
- 1,581
- References
- 117
- Citations by year
- 2026: 39 · 2025: 57 · 2024: 69 · 2023: 60 · 2022: 75 · 2021: 118 · 2020: 121 · 2019: 121 · 2018: 132 · 2017: 148 · 2016: 134 · 2015: 147 · 2014: 134 · 2013: 123 · 2012: 80
- FWCI
- 10.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Cognitive Sciences (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Beatrice and Samuel A. Seaver Foundation
- National Institutes of Health
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD065276-01, R21HD065276)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Keywords
- oxytocin, social cognition, prosocial behavior, sociality, interactionism, context effects, individual differences
- MeSH terms
- Animals, Brain, Cognition Disorders, Humans, Oxytocin, Social Behavior
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