The role of microbiota in infectious disease

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444

Human gut microbes associated with obesity

Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785

Obesity alters gut microbial ecology

Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504978102 · Cited by 6,176

Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine

Ley, R. E., Peterson, D. A., & Gordon, J. I. (2006) · Cell · doi:10.1016/j.cell.2006.02.017 · Cited by 3,358

Defensins: antimicrobial peptides of innate immunity

Ganz, T. (2003) · Nature Reviews Immunology · doi:10.1038/nri1180 · Cited by 3,066

Development of the Human Infant Intestinal Microbiota

Palmer, C., Bik, E. M., DiGiulio, D. B., Relman, D. A., & Brown, P. O. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050177 · Cited by 2,877

The gut flora as a forgotten organ

O'Hara, A. M., & Shanahan, F. (2006) · The EMBO Reports · doi:10.1038/sj.embor.7400731 · Cited by 2,791

Symbiotic bacteria direct expression of an intestinal bactericidal lectin

Cash, H. L., Whitham, C. V., Behrendt, C. L., & Hooper, L. V. (2006) · Science · doi:10.1126/science.1127119 · Cited by 1,432

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

Stecher, B., Robbiani, R., Walker, A. W., Westendorf, A. M., Barthel, M., Kremer, M., Chaffron, S., Macpherson, A. J., Buer, J., Parkhill, J., et al. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050244 · Cited by 1,048

The Microbial Ecology of the Large Bowel of Breastfed and Formula-fed Infants During the First Year of Life

Stark, P. L., & Lee, A. (1982) · Journal of Medical Microbiology · doi:10.1099/00222615-15-2-189 · Cited by 616

Gut microbiota in human metabolic health and disease

Fan, Y., & Pedersen, O. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0433-9 · Cited by 4,724

Gut microbiota in health and disease

Sekirov, I., Russell, S. L., Antunes, L. C. M., & Finlay, B. B. (2010) · Physiological Reviews · doi:10.1152/physrev.00045.2009 · Cited by 4,182

Enteric defensins are essential regulators of intestinal microbial ecology

Salzman, N. H., Hung, K., Haribhai, D., Chu, H., Karlsson-Sjöberg, J., Amir, E., Teggatz, P., Barman, M., Hayward, M., Eastwood, D., et al. (2010) · Nature Immunology · doi:10.1038/ni.1825 · Cited by 1,156

Impacts of gut bacteria on human health and diseases

Zhang, Y.-J., Li, S., Gan, R.-Y., Zhou, T., Xu, D.-P., & Li, H.-B. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16047493 · Cited by 1,055

The human gut microbiome: ecology and recent evolutionary changes

Walter, J., & Ley, R. (2011) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090110-102830 · Cited by 720

Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis

Buffie, C. G., Jarchum, I., Equinda, M., Lipuma, L., Gobourne, A., Viale, A., Ubeda, C., Xavier, J., & Pamer, E. G. (2012) · Infection and Immunity · doi:10.1128/iai.05496-11 · Cited by 596

Intestinal colonization resistance

Lawley, T. D., & Walker, A. W. (2013) · Immunology · doi:10.1111/j.1365-2567.2012.03616.x · Cited by 610

The Effects of Iron Fortification on the Gut Microbiota in African Children: A Randomized Controlled Trial in Cote d’Ivoire

Zimmermann, M. B., Chassard, C., Rohner, F., N'Goran, E. K., Nindjin, C., Dostal, A., Utzinger, J., Ghattas, H., Lacroix, C., & Hurrell, R. F. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.004564 · Cited by 520

Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to Exacerbated Citrobacter rodentium -Induced Colitis

Wlodarska, M., Willing, B., Keeney, K. M., Menendez, A., Bergstrom, K. S., Gill, N., Russell, S. L., Vallance, B. A., & Finlay, B. B. (2011) · Infection and Immunity · doi:10.1128/iai.01104-10 · Cited by 382

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

Fachi, J. L., Felipe, J. D. S., Pral, L. P., da Silva, B. K., Corrêa, R. O., de Andrade, M. C. P., da Fonseca, D. M., Basso, P. J., Câmara, N. O. S., de Sales e Souza, É. L., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.03.054 · Cited by 364

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

Lawley, T. D., Clare, S., Walker, A. W., Goulding, D., Stabler, R. A., Croucher, N., Mastroeni, P., Scott, P., Raisen, C., Mottram, L., et al. (2009) · Infection and Immunity · doi:10.1128/iai.00558-09 · Cited by 349

The Airway Microbiota in Cystic Fibrosis: A Complex Fungal and Bacterial Community—Implications for Therapeutic Management

Delhaes, L., Monchy, S., Fréalle, E., Hubans, C., Salleron, J., Leroy, S., Prevotat, A., Wallet, F., Wallaert, B., Dei-Cas, E., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036313 · Cited by 347

Nutritional Basis for Colonization Resistance by Human Commensal Escherichia coli Strains HS and Nissle 1917 against E. coli O157:H7 in the Mouse Intestine

Maltby, R., Leatham-Jensen, M. P., Gibson, T., Cohen, P. S., & Conway, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053957 · Cited by 285

Nutritional iron turned inside out: intestinal stress from a gut microbial perspective

Kortman, G. A. M., Raffatellu, M., Swinkels, D. W., & Tjalsma, H. (2014) · FEMS Microbiology Reviews · doi:10.1111/1574-6976.12086 · Cited by 291

Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model

Wang, F., Meng, J., Zhang, L., Johnson, T., Chen, C., & Roy, S. (2018) · Scientific Reports · doi:10.1038/s41598-018-21915-8 · Cited by 238

The non-pathogenic Escherichia coli strain Nissle 1917 – features of a versatile probiotic

Sonnenborn, U., & Schulze, J. (2009) · Microbial Ecology in Health and Disease · doi:10.3109/08910600903444267 · Cited by 232

Life in the inflamed intestine, Salmonella style

Santos, R. L., Raffatellu, M., Bevins, C. L., Adams, L. G., Tükel, Ç., Tsolis, R. M., & Bäumler, A. J. (2009) · Trends in Microbiology · doi:10.1016/j.tim.2009.08.008 · Cited by 197

Early innate immunity to bacterial infection in the lung is regulated systemically by the commensal microbiota via nod-like receptor ligands

Clarke, T. B. (2014) · Infection and Immunity · doi:10.1128/iai.02212-14 · Cited by 189

Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia

Picca, A., Fanelli, F., Calvani, R., Mulè, G., Pesce, V., Sisto, A., Pantanelli, C., Bernabei, R., Landi, F., & Marzetti, E. (2018) · Mediators of Inflammation · doi:10.1155/2018/7026198 · Cited by 181

Environmentally Determined Differences in the Murine Lung Microbiota and Their Relation to Alveolar Architecture

Yun, Y., Srinivas, G., Kuenzel, S., Linnenbrink, M., Alnahas, S., Bruce, K. D., Steinhoff, U., Baines, J. F., & Schaible, U. E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113466 · Cited by 168

Low iron availability in continuous in vitro colonic fermentations induces strong dysbiosis of the child gut microbial consortium and a decrease in main metabolites

Dostal, A., Fehlbaum, S., Chassard, C., Zimmermann, M. B., & Lacroix, C. (2013) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2012.01461.x · Cited by 129

Effects of iron supplementation on dominant bacterial groups in the gut, faecal SCFA and gut inflammation: a randomised, placebo-controlled intervention trial in South African children

Dostal, A., Baumgartner, J., Riesen, N., Chassard, C., Smuts, C. M., Zimmermann, M. B., & Lacroix, C. (2014) · British Journal of Nutrition · doi:10.1017/s0007114514001160 · Cited by 121

Cross-Sectional and Longitudinal Comparisons of the Predominant Fecal Microbiota Compositions of a Group of Pediatric Patients with Cystic Fibrosis and Their Healthy Siblings

Duytschaever, G., Huys, G., Bekaert, M., Boulanger, L., De Boeck, K., & Vandamme, P. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.05933-11 · Cited by 114

Current level of consensus on probiotic science-Report of an expert meeting-London, 23 November 2009

Rowland, I. R., Capurso, L., Collins, K., Cummings, J., Delzenne, N., Goulet, O., Guarner, F., Marteau, P., & Meier, R. (2010) · Gut Microbes · doi:10.4161/gmic.1.6.13610 · Cited by 109

Identification of clinical and ecological determinants of strain engraftment after fecal microbiota transplantation using metagenomics

Podlesny, D., Durdevic, M., Paramsothy, S., Kaakoush, N. O., Högenauer, C., Gorkiewicz, G., Walter, J., & Fricke, W. F. (2022) · Cell Reports Medicine · doi:10.1016/j.xcrm.2022.100711 · Cited by 111

Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities

Krumbeck, J. A., Walter, J., & Hutkins, R. W. (2018) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-030117-012757 · Cited by 84

Antimicrobial resistance risk factors and characterisation of faecal E. coli isolated from healthy Labrador retrievers in the United Kingdom

Schmidt, V. M., Pinchbeck, G. L., Nuttall, T., McEwan, N., Dawson, S., & Williams, N. J. (2015) · Preventive Veterinary Medicine · doi:10.1016/j.prevetmed.2015.01.013 · Cited by 67

Models for Gut-Mediated Horizontal Gene Transfer by Bacterial Plasmid Conjugation

Ott, L. C., & Mellata, M. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.891548 · Cited by 32

Fecal microbiota transplantation for Clostridium difficile infection: benefits and barriers

Lo Vecchio, A., & Cohen, M. B. (2014) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000023 · Cited by 27

Alterations in the gastric microbiota and metabolites in gastric cancer: An update review

Lei, C., Gong, D., Zhuang, B., & Zhang, Z. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.960281 · Cited by 20

Probiotic Potential of Yeasts Isolated from Fermented Beverages: Assessment of Antagonistic Strategies Against Salmonella enterica Serovar Enteritidis

Alvarez, S. C. V., Pendón, M. D., Bengoa, A. A., Leiva Alaniz, M. J., Maturano, Y. P., & Garrote, G. L. (2024) · Journal of Fungi · doi:10.3390/jof10120878 · Cited by 9