Cited by 84Probiotics and Fermented FoodsMicrobial Metabolites in Food BiotechnologyInfant Nutrition and Health

Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities

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Krumbeck, Janina A., Walter, Jens, Hutkins, Robert W.·2018·Annual Review of Food Science and Technology

Abstract

Research on combining pro- and prebiotics as synbiotics to enhance human and animal health has accelerated in the past 10 years, including many clinical trials that have assessed a diverse range of synbiotic formulations. In this review, we summarize these studies as well as the commercial applications of synbiotics that are available. In particular, we critically assess the claimed health benefits of synbiotic applications and the ecological and therapeutic factors to consider when designing synbiotics and discuss the implications of these concepts for future research in this field.

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Crossref · 10.1146/annurev-food-030117-012757

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Research works printed but not linked: 13

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Authors
Krumbeck, J. A., Walter, J., & Hutkins, R. W.
Affiliations
  • University of Nebraska–Lincoln (US)
  • University of Alberta (CA)
Venue
Annual Review of Food Science and Technology
Published
2018-03-25
Volume
9
Issue
1
Pages
451-479
ISSN
  • 1941-1421 (ISSN-L)
  • 1941-1413
OpenAlex
W2619400681
Cited by
84
References
170
Citations by year
2026: 12 · 2025: 10 · 2024: 16 · 2023: 9 · 2022: 11 · 2021: 6 · 2020: 8 · 2019: 8 · 2018: 4
FWCI
0.66
Type
journal article
Language
en
Open access
Locations
  • Annual Review of Food Science and Technology (publishedVersion)
  • PubMed (publishedVersion)
  • Lincoln (University of Nebraska) (submittedVersion)
Funders
  • U.S. Department of Agriculture
  • European Food Safety Authority
  • European Commission
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Keywords
synbiotics, probiotics, prebiotics, gut microbiota, human health, animal health, clinical trials, health claims
MeSH terms
Gastrointestinal Microbiome, Clinical Trials as Topic, Humans, Synbiotics

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