Cited by 594Posttraumatic Stress Disorder ResearchMemory and Neural MechanismsMemory Processes and Influences

The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.

The functional neuroanatomy of PTSD: a critical review

Liberzon, Israel, Sripada, Chandra Sekhar·2007·Progress in Brain Research

Open this paper in CoChat — free account

Abstract

Neuroimaging provides an opportunity to understand core processes that mediate the experience of emotions in healthy individuals as well as dysregulation of these processes in conditions such as posttraumatic stress disorder (PTSD). The first decade of neuroimaging research produced symptom provocation, cognitive activation, and functional connectivity studies that highlighted the role of the medial prefrontal cortex (mPFC), amygdala, sublenticular extended amygdala (SLEA), and hippocampus, in mediating symptom formation in PTSD. There is a growing realization that a number of other psychological processes are relevant to PTSD, and they are emerging as a new focus of neuroimaging research. These include fear conditioning, habituation, and extinction; cognitive-emotional interactions; and self-related and social emotional processing. Neuroimaging findings are reviewed that suggest that the mPFC is implicated in a number of these processes. It is proposed that the mPFC plays a role in the "contextualization" of stimuli, and dysregulation of contextualization processes might play a key role in the generation of PTSD symptoms.

Integrity signals

Registry

Crossref · 10.1016/s0079-6123(07)67011-3

Cites

71 of 71 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Posttraumatic Stress Disorder in the National Comorbidity Survey
Kessler, R. C. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950240066012 · Cited by 10,379
The emerging field of emotion regulation: an integrative review
Gross, J. J. (1998) · Review of General Psychology · doi:10.1037/1089-2680.2.3.271 · Cited by 9,916
Emotion circuits in the brain
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Cognitive and emotional influences in anterior cingulate cortex
Bush, G., Luu, P., & Posner, M. I. (2000) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01483-2 · Cited by 6,259
The amygdala: vigilance and emotion
Davis, M., & Whalen, P. J. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000812 · Cited by 2,882
International Affective Picture System (IAPS) : Technical Manual and Affective Ratings
Lang, P. J. (1995) · Medical Entomology and Zoology · Cited by 2,870
Rethinking feelings: an fMRI study of the cognitive regulation of emotion
Ochsner, K. N., Bunge, S. A., Gross, J. J., & Gabrieli, J. D. E. (2002) · Journal of Cognitive Neuroscience · doi:10.1162/089892902760807212 · Cited by 2,520
Masked Presentations of Emotional Facial Expressions Modulate Amygdala Activity without Explicit Knowledge
Whalen, P. J., Rauch, S. L., Etcoff, N. L., McInerney, S. C., Lee, M. B., & Jenike, M. A. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00411.1998 · Cited by 2,205
Functional Connectivity: The Principal-Component Analysis of Large (PET) Data Sets
Friston, K. J., Frith, C., Liddle, P. F., & Frackowiak, R. S. J. (1993) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1993.4 · Cited by 1,997
A cortical–hippocampal system for declarative memory
Eichenbaum, H. (2000) · Nature reviews. Neuroscience · doi:10.1038/35036213 · Cited by 1,817

Show all 71 references

Sorted by citations

Items 101–200 of 594

The Missing P in Psychiatric Training
Elman, I., Zubieta, J.-K., & Borsook, D. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.174 · Cited by 115
Cognitive Sequelae of Blast-Induced Traumatic Brain Injury: Recovery and Rehabilitation
Bogdanova, Y., & Verfaellie, M. H. (2012) · Neuropsychology Review · doi:10.1007/s11065-012-9192-3 · Cited by 120
Unconscious emotion: A cognitive neuroscientific perspective
Smith, R. S., & Lane, R. D. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.013 · Cited by 118
Fear potentiation is associated with hypothalamic–pituitary–adrenal axis function in PTSD
Jovanović, T., Norrholm, S. D., Blanding, N. Q., Phifer, J. E., Weiss, T., Davis, M., Duncan, E., Bradley, B., & Ressler, K. J. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.11.009 · Cited by 115
A Ketogenic Diet Improves Cognition and Has Biochemical Effects in Prefrontal Cortex That Are Dissociable From Hippocampus
Hernandez, A. R., Hernandez, C. M., Campos, K., Truckenbrod, L., Federico, Q., Moon, B., McQuail, J. A., Maurer, A. P., Bizon, J. L., & Burke, S. N. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00391 · Cited by 111
Effects of Low-Level Blast Exposure on the Nervous System: Is There Really a Controversy?
Elder, G. A., Stone, J. R., & Ahlers, S. T. (2014) · Frontiers in Neurology · doi:10.3389/fneur.2014.00269 · Cited by 113
Neural signatures of conditioning, extinction learning, and extinction recall in posttraumatic stress disorder: a meta-analysis of functional magnetic resonance imaging studies
Suarez‐Jimenez, B., Albajes‐Eizagirre, A., Lazarov, A., Zhu, X., Harrison, B. J., Raduà, J., Neria, Y., & Fullana, M. A. (2019) · Psychological Medicine · doi:10.1017/s0033291719001387 · Cited by 125
Can’t get it out of my mind: A systematic review of predictors of intrusive memories of distressing events.
Marks, E. H., Franklin, A. R., & Zoellner, L. A. (2018) · Psychological Bulletin · doi:10.1037/bul0000132 · Cited by 127
Increased anterior cingulate cortex and hippocampus activation in Complex PTSD during encoding of negative words
Thomaes, K., Dorrepaal, E., Draijer, N., de Ruiter, M. B., Elzinga, B. M., Sjoerds, Z., van Balkom, A. J., Smit, J. H., & Veltman, D. J. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsr084 · Cited by 103
Neural circuitry of PTSD with or without mild traumatic brain injury: a meta-analysis
Simmons, A. N., & Matthews, S. C. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.03.016 · Cited by 105
Neurobiology of resilience
Feder, A., Charney, D. S., & Collins, K. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511994791.003 · Cited by 105
A behavioural neuroscience perspective on the aetiology and treatment of anxiety disorders
Kindt, M. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.08.012 · Cited by 103
Is posttraumatic stress disorder a stress‐induced fear circuitry disorder?
Shin, L. M., & Handwerger, K. (2009) · Journal of Traumatic Stress · doi:10.1002/jts.20442 · Cited by 102
Default mode network subsystems are differentially disrupted in posttraumatic stress disorder
Miller, D. R., Hayes, S. M., Hayes, J. P., Spielberg, J. M., Lafleche, G., & Verfaellie, M. (2017) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2016.12.006 · Cited by 101
The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Shin, L. M., & Liberzon, I. (2011) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.9.3.foc311 · Cited by 105
Self-citation
Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure
Dickstein, D. L., Gasperi, R. D., Sosa, M. A. G., Perez-Garcia, G., Short, J. A., Sosa, H., Perez, G. M., Tschiffely, A. E., Dams-O’Connor, K., Pullman, M. Y., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0674-z · Cited by 97
Can pharmacological and psychological treatment change brain structure and function in PTSD? A systematic review
Thomaes, K., Dorrepaal, E., Draijer, N., Jansma, E. P., Veltman, D. J., & van Balkom, A. J. L. M. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.11.002 · Cited by 105
Prevention of Stress-Impaired Fear Extinction Through Neuropeptide S Action in the Lateral Amygdala
Chauveau, F., Lange, M. D., Jüngling, K., Lesting, J., Seidenbecher, T., & Pape, H. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.3 · Cited by 99
Neural Mechanisms of Grief Regulation
Freed, P. J., Yanagihara, T. K., Hirsch, J., & Mann, J. J. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.01.019 · Cited by 100
Volitional regulation of emotions produces distributed alterations in connectivity between visual, attention control, and default networks
Sripada, C., Angstadt, M., Kessler, D. A., Phan, K. L., Liberzon, I., Evans, G. W., Welsh, R. C., Kim, P., & Swain, J. E. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.11.006 · Cited by 99
Self-citation
Neural responses during emotional processing before and after cognitive trauma therapy for battered women.
Aupperle, R. L., Allard, C. B., Simmons, A. N., Flagan, T., Thorp, S. R., Norman, S. B., Paulus, M. P., & Stein, M. B. (2013) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2013.05.001 · Cited by 93
BDNF serum levels in subjects developing or not post-traumatic stress disorder after trauma exposure
Angelucci, F., Ricci, V., Gelfo, F., Martinotti, G., Brunetti, M., Sepede, G., Signorelli, M. S., Aguglia, E., Pettorruso, M., Vellante, F., et al. (2013) · Brain and Cognition · doi:10.1016/j.bandc.2013.11.012 · Cited by 101
Serotonin norepinephrine reuptake inhibitors (SNRIs) in anxiety disorders: a comprehensive review of their clinical efficacy
Dell’Osso, B. M., Buoli, M., Baldwin, D. S., & Altamura, A. C. (2009) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.1074 · Cited by 94
Dimensional depression severity in women with major depression and post-traumatic stress disorder correlates with fronto-amygdalar hypoconnectivty
Satterthwaite, T. D., Cook, P. A., Bruce, S. E., Conway, C. R., Mikkelsen, E., Satchell, E. K., Vandekar, S., Durbin, T. J., Shinohara, R. T., & Sheline, Y. I. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.149 · Cited by 90
Associations Between Specific Negative Emotions and DSM-5 PTSD Among a National Sample of Interpersonal Trauma Survivors
Badour, C. L., Resnick, H. S., & Kilpatrick, D. G. (2015) · Journal of Interpersonal Violence · doi:10.1177/0886260515589930 · Cited by 90
The resilient brain: psychological resilience mediates the effect of amplitude of low-frequency fluctuations in orbitofrontal cortex on subjective well-being in young healthy adults
Kong, F., Ma, X., You, X., & Xiang, Y. (2018) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsy045 · Cited by 90
Glucocorticoid mechanisms of functional connectivity changes in stress-related neuropsychiatric disorders
Hall, B. S., Moda, R. N., & Liston, C. M. (2014) · Neurobiology of Stress · doi:10.1016/j.ynstr.2014.10.008 · Cited by 94
Pretreatment biomarkers predicting PTSD psychotherapy outcomes: A systematic review
Colvonen, P. J., Glassman, L. H., Crocker, L. D., Buttner, M. M. A., Orff, H. J., Schiehser, D. M., Norman, S. B., & Afari, N. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.027 · Cited by 89
Negative life experiences contribute to racial differences in the neural response to threat
Harnett, N. G., Wheelock, M. D., Wood, K. H., Goodman, A. M., Mrug, S., Elliott, M. N., Schuster, M. A., Tortolero, S. R., & Knight, D. C. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.116086 · Cited by 91
Oxytocin Reduces Background Anxiety in a Fear-Potentiated Startle Paradigm: Peripheral vs Central Administration
Ayers, L. W., Missig, G., Schulkin, J. A., & Rosen, J. B. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.138 · Cited by 87
Affiliation buffers stress: cumulative genetic risk in oxytocin–vasopressin genes combines with early caregiving to predict PTSD in war-exposed young children
Feldman, R., Vengrober, A., & Ebstein, R. P. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.6 · Cited by 87
Medial prefrontal cortex activity can disrupt the expression of stress response habituation
Weinberg, M. S., Johnson, D. C., Bhatt, A. P., & Spencer, R. L. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.04.006 · Cited by 88
The effects of trauma on brain and body: A unifying role for the midbrain periaqueductal gray
Terpou, B. A., Harricharan, S., McKinnon, M. C., Frewen, P., Jetly, R., & Lanius, R. A. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24447 · Cited by 82
Neural functional and structural correlates of childhood maltreatment in women with intimate-partner violence-related posttraumatic stress disorder
Fonzo, G. A., Flagan, T., Sullivan, S. A., Allard, C. B., Grimes, E. M., Simmons, A. N., Paulus, M. P., & Stein, M. B. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2012.08.006 · Cited by 89
Reduced amygdala serotonin transporter binding in posttraumatic stress disorder
Murrough, J. W., Huang, Y., Hu, J., Henry, S., Williams, W., Gallezot, J.-D., Bailey, C. R., Krystal, J. H., Carson, R. E., & Neumeister, A. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.07.003 · Cited by 92
Oxytocin Reduces Background Anxiety in a Fear-Potentiated Startle Paradigm
Missig, G., Ayers, L. W., Schulkin, J., & Rosen, J. B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.155 · Cited by 79
Anxiety- and depressive-like responses and c-fos activity in preproenkephalin knockout mice: Oversensitivity hypothesis of enkephalin deficit-induced posttraumatic stress disorder
Kung, J.-C., Chen, J. T.-C., Shyu, B., Hsiao, S., & Huang, A. C. W. (2010) · Journal of Biomedical Science · doi:10.1186/1423-0127-17-29 · Cited by 77
PTSD and cognitive symptoms relate to inhibition-related prefrontal activation and functional connectivity
Clausen, A. N., Francisco, A. J., Thelen, J., Bruce, J. M., Martin, L. E., McDowd, J. M., Simmons, W. K., & Aupperle, R. L. (2017) · Depression and Anxiety · doi:10.1002/da.22613 · Cited by 84
Avoidant symptoms in PTSD predict fear circuit activation during multimodal fear extinction
Sripada, R. K., Garfinkel, S. N., & Liberzon, I. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00672 · Cited by 87
Self-citation
Cerebellar and Prefrontal Cortical Alterations in PTSD: Structural and Functional Evidence
Holmes, S. E., Scheinost, D., DellaGioia, N., Davis, M. T., Matuskey, D., Pietrzak, R. H., Hampson, M., Krystal, J. H., & Esterlis, I. (2018) · Chronic Stress · doi:10.1177/2470547018786390 · Cited by 78
Intranasal infusion of melanocortin receptor four (MC4R) antagonist to rats ameliorates development of depression and anxiety related symptoms induced by single prolonged stress
Serova, L. I., Lauková, M., Alaluf, L. G., & Sabban, E. L. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.05.006 · Cited by 76
Inhibition of projections from the basolateral amygdala to the entorhinal cortex disrupts the acquisition of contextual fear
Sparta, D. R., Smithuis, J., Stamatakis, A. M., Jennings, J. H., Kantak, P. A., Ung, R. L., & Stuber, G. D. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00129 · Cited by 75
Post-Traumatic Stress Disorder: The Relationship Between the Fear Response and Chronic Stress
Maeng, L. Y., & Milad, M. R. (2017) · Chronic Stress · doi:10.1177/2470547017713297 · Cited by 92
Neuroanatomical features in soldiers with post-traumatic stress disorder
Sussman, D., Pang, E. W., Jetly, R., Dunkley, B. T., & Taylor, M. J. (2016) · BMC Neuroscience · doi:10.1186/s12868-016-0247-x · Cited by 80
The memory and identity theory of ICD-11 complex posttraumatic stress disorder.
Hyland, P., Shevlin, M. E., & Brewin, C. R. (2023) · Psychological Review · doi:10.1037/rev0000418 · Cited by 95
Decreased regional cerebral blood flow in medial prefrontal cortex during trauma-unrelated stressful imagery in Vietnam veterans with post-traumatic stress disorder
Gold, A. L., Shin, L. M., Orr, S. P., Carson, M. A., Rauch, S. L., Macklin, M. L., Lasko, N. B., Metzger, L. J., Dougherty, D. D., Alpert, N. M., et al. (2011) · Psychological Medicine · doi:10.1017/s0033291711000730 · Cited by 77
Anterior hippocampal dysconnectivity in posttraumatic stress disorder: a dimensional and multimodal approach
Abdallah, C. G., Wrocklage, K. M., Averill, C. L., Akiki, T. J., Schweinsburg, B. C., Roy, A. M., Martini, B. A., Southwick, S. M., Krystal, J. H., & Scott, J. C. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.12 · Cited by 69
Predictive and Associated Factors of Psychiatric Disorders after Traumatic Brain Injury: A Prospective Study
Gould, K. R., Ponsford, J. L., Johnston, L., & Schönberger, M. (2011) · Journal of Neurotrauma · doi:10.1089/neu.2010.1528 · Cited by 71
Posttraumatic stress disorder and breast cancer: Risk factors and the role of inflammation and endocrine function
Brown, L. C., Murphy, A. R., Lalonde, C. S., Subhedar, P. D., Miller, A. H., & Stevens, J. S. (2020) · Cancer · doi:10.1002/cncr.32934 · Cited by 73
Fear learning and memory across adolescent development
Pattwell, S. S., Lee, F. S., & Casey, B. J. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.01.016 · Cited by 74
Cortisol suppression by dexamethasone reduces exaggerated fear responses in posttraumatic stress disorder
Jovanović, T., Phifer, J. E., Sicking, K., Weiss, T., Norrholm, S. D., Bradley, B., & Ressler, K. J. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.04.008 · Cited by 71
Functional network topology associated with posttraumatic stress disorder in veterans
Kennis, M., van Rooij, S. J. H., van den Heuvel, M. P., Kahn, R. S., & Geuze, E. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.12.008 · Cited by 69
Circuit dysregulation and circuit-based treatments in posttraumatic stress disorder
Sheynin, J., & Liberzon, I. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2016.11.014 · Cited by 68
“Dysfunction in the contextual processing circuit may lead to inflexible, rigid and inappropriate behavioral responses, contributing to development of various PTSD symptoms [3, 39, 40].”
BackgroundSelf-citation
Augmenting treatment efficiency in exposure therapy for PTSD: a randomized double-blind placebo-controlled trial of yohimbine HCl
Tuerk, P. W., Wangelin, B. C., Powers, M. B., Smits, J. A. J., Acierno, R. E., Myers, U. S., Orr, S. P., Foa, E. B., & Hamner, M. B. (2018) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2018.1432679 · Cited by 70
Neural systems for cognitive and emotional processing in posttraumatic stress disorder.
Brown, V. M., & Morey, R. A. (2012) · Frontiers in Psychology · doi:10.3389/fpsyg.2012.00449 · Cited by 67
Serotonin polymorphisms and posttraumatic stress disorder in a trauma exposed African American population
Mellman, T. A., Alim, T. N., Brown, D. D., Gorodetsky, E. K., Búzás, B., Lawson, W. B., Goldman, D. A., & Charney, D. S. (2009) · Depression and Anxiety · doi:10.1002/da.20627 · Cited by 66
Ensemble machine learning prediction of posttraumatic stress disorder screening status after emergency room hospitalization
Papini, S., Pisner, D., Shumake, J., Powers, M. B., Beevers, C. G., Rainey, E. E., Smits, J. A. J., & Warren, A. M. (2018) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2018.10.004 · Cited by 74
Memory as a new therapeutic target
Nader, K., Hardt, O. M., & Lanius, R. A. (2013) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2013.15.4/knader · Cited by 67
Anatomical and functional connectivity in the default mode network of post‐traumatic stress disorder patients after civilian and military‐related trauma
Reuveni, I., Bonne, O. B., Giesser, R., Shragai, T., Lazarovits, G., Isserles, M., Schreiber, S., Bick, A. S., & Levin, N. (2015) · Human Brain Mapping · doi:10.1002/hbm.23051 · Cited by 70
Animal models of post-traumatic stress disorder and novel treatment targets
Aspesi, D., & Pinna, G. (2019) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000467 · Cited by 67
A Pilot Study of Mindfulness-Based Exposure Therapy in OEF/OIF Combat Veterans with PTSD: Altered Medial Frontal Cortex and Amygdala Responses in Social–Emotional Processing
King, A. P., Block, S. R., Sripada, R. K., Rauch, S. A. M., Porter, K. E., Favorite, T. K., Giardino, N., & Liberzon, I. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00154 · Cited by 64
Self-citation
Focus on HTR2C: A possible suggestion for genetic studies of complex disorders
Drago, A., & Serretti, A. (2008) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30864 · Cited by 66
Impaired hippocampus-dependent associative learning as a mechanism underlying PTSD: A meta-analysis
Lambert, H. K., & McLaughlin, K. A. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.09.024 · Cited by 71
Enduring sensorimotor gating abnormalities following predator exposure or corticotropin-releasing factor in rats: A model for PTSD-like information-processing deficits?
Bakshi, V. P., Alsene, K. M., Roseboom, P. H., & Connors, E. E. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.01.040 · Cited by 59
Behavioral and brain mechanisms mediating conditioned flight behavior in rats
Totty, M. S., Warren, N., Huddleston, I., Ramanathan, K. R., Ressler, R. L., Oleksiak, C. R., & Maren, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-87559-3 · Cited by 58
Post-traumatic stress disorder: a psychiatric disorder requiring urgent attention
Du, J., Diao, H., Zhou, X., Zhang, C., Chen, Y., Gao, Y. F., & Wang, Y. (2022) · Medical Review · doi:10.1515/mr-2022-0012 · Cited by 69
Behaviorally inhibited temperament is associated with severity of post-traumatic stress disorder symptoms and faster eyeblink conditioning in veterans
Myers, C. E., VanMeenen, K. M., McAuley, J. D., Beck, K. D., Pang, K. C. H., & Servatius, R. J. (2011) · Stress · doi:10.3109/10253890.2011.578184 · Cited by 58
Acute reversible inactivation of the ventral medial prefrontal cortex induces antidepressant-like effects in rats
Scopinho, A. A., Scopinho, M., Lisboa, S. F. D. S., Corrêa, F. M. D. A., Guimarães, F. S., & Joca, S. R. L. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.06.018 · Cited by 62
Involvement of the Ventral Tegmental Area in a Rodent Model of Post-Traumatic Stress Disorder
Corral-Frías, N. S., Lahood, R. P., Edelman-Vogelsang, K. E., French, E. D., & Fellous, J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.189 · Cited by 58
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
Norrholm, S., & Jovanovic, T. (2010) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s10951 · Cited by 56
Pre- and postictal, not ictal, heart rate distinguishes complex partial and psychogenic nonepileptic seizures
Reinsberger, C., Perez, D. L., Murphy, M. M., & Dworetzky, B. A. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2011.10.008 · Cited by 56
Connectome-wide investigation of altered resting-state functional connectivity in war veterans with and without posttraumatic stress disorder
Misaki, M., Phillips, R., Zotev, V. S., Wong, C. K., Wurfel, B. E., Krüeger, F., Feldner, M. T., & Bodurka, J. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2017.10.032 · Cited by 57
The brain’s hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers
Elbau, I., Brücklmeier, B., Uhr, M., Arloth, J., Czamara, D., Spoormaker, V. I., Czisch, M., Stephan, K. E., Binder, E. B., & Sämann, P. G. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1804340115 · Cited by 57
Hyperbaric Oxygen Therapy Can Induce Neuroplasticity and Significant Clinical Improvement in Patients Suffering From Fibromyalgia With a History of Childhood Sexual Abuse—Randomized Controlled Trial
Hadanny, A., Bechor, Y., Catalogna, M., Daphna‐Tekoah, S., Tal, S., Cohenpour, M., Lev‐Wiesel, R., & Efrati, S. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.02495 · Cited by 59
Imaging Stress Effects on Memory: A Review of Neuroimaging Studies
van Stegeren, A. H. (2009) · The Canadian Journal of Psychiatry · doi:10.1177/070674370905400105 · Cited by 56
Decreased Premotor Cortex Volume in Victims of Urban Violence with Posttraumatic Stress Disorder
Rocha-Rego, V., Pereira, M. G., Oliveira, L., Mendlowicz, M. V., Fiszman, A., Marques-Portella, C., Berger, W., Chu, C., Joffily, M., Moll, J., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042560 · Cited by 55
Diminished positive affect and traumatic stress: A biobehavioral review and commentary on trauma affective neuroscience
Fonzo, G. A. (2018) · Neurobiology of Stress · doi:10.1016/j.ynstr.2018.10.002 · Cited by 58
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD
Perl, O., Duek, O. A., Kulkarni, K. R., Kelmendi, B., Amen, S. L., Gordon, C., Krystal, J. H., Levy, I., Harpaz‐Rotem, I., & Schiller, D. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01483-5 · Cited by 61
Translationally relevant modeling of PTSD in rodents
Matar, M. A., Zohar, J., & Cohen, H. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1687-6 · Cited by 55
The center of the emotional universe: Alcohol, stress, and CRF1 amygdala circuitry
Agoglia, A. E., & Herman, M. A. (2018) · Alcohol · doi:10.1016/j.alcohol.2018.03.009 · Cited by 57
Trauma exposure and sleep: using a rodent model to understand sleep function in PTSD
Vanderheyden, W. M., Poe, G. R., & Liberzon, I. (2014) · Experimental Brain Research · doi:10.1007/s00221-014-3890-4 · Cited by 56
Self-citation
The neurokinin-1 receptor antagonist aprepitant in co-morbid alcohol dependence and posttraumatic stress disorder: a human experimental study
Kwako, L. E., George, D. T., Schwandt, M. L., Spagnolo, P. A., Momenan, R., Hommer, D. W., Diamond, C. A., Sinha, R., Shaham, Y., & Heilig, M. A. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3665-4 · Cited by 54
Psychopathological, biological, and neuroimaging characterization of posttraumatic stress disorder in survivors of a severe coalmining disaster in China
Wang, H., Zhang, Z., Tan, Q., Yin, H. J., Chen, Y., Wang, H., Zhang, R., Wang, Z., Guo, L., Tang, L., et al. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.10.001 · Cited by 52
White matter abnormalities in Gulf War veterans with posttraumatic stress disorder: A pilot study
Bierer, L. M., Ivanov, I., Carpenter, D. M., Wong, E. W., Golier, J. A., Tang, C. Y., & Yehuda, R. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.11.007 · Cited by 52
Reward and aversion processing in patients with post-traumatic stress disorder: functional neuroimaging with visual and thermal stimuli
Elman, I., Upadhyay, J., Langleben, D. D., Albanese, M. A., Becerra, L. R., & Borsook, D. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0292-6 · Cited by 52
Modelling posttraumatic stress disorders in animals
Török, B., Sipos, E., Pivac, N., & Zelena, D. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.11.013 · Cited by 58
Prefrontal responses to Stroop tasks in subjects with post-traumatic stress disorder assessed by functional near infrared spectroscopy
Yennu, A. S., Tian, F., Smith‐Osborne, A., Gatchel, R. J., Woon, F. L. M., & Liu, H. (2016) · Scientific Reports · doi:10.1038/srep30157 · Cited by 56
The failing cascade: Comorbid post traumatic stress- and opioid use disorders
Elman, I., & Borsook, D. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.04.023 · Cited by 52
Gender Differences in the Relationship between Maladaptive Behaviors and Post-Traumatic Stress Disorder. A Study on 900 L’ Aquila 2009 Earthquake Survivors
eDell'Osso, L., Carmassi, C., Stratta, P., eMassimetti, G., Akiskal, K. K., Akiskal, H. S., Maremmani, I., & Rossi, A. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00111 · Cited by 50
Altered amygdala activation during face processing in Iraqi and Afghanistani war veterans
Simmons, A. N., Matthews, S. C., Strigo, I. A., Baker, D. G., Donovan, H., Motezadi, A., Stein, M. B., & Paulus, M. P. (2011) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-1-6 · Cited by 54
Modulatory mechanisms of cortisol effects on emotional learning and memory: Novel perspectives
van Ast, V. A., Cornelisse, S., Marin, M., Ackermann, S., Garfinkel, S. N., & Abercrombie, H. C. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.06.012 · Cited by 53
Blast-induced "PTSD": Evidence from an animal model
Perez-Garcia, G., Sosa, M. A. G., Gasperi, R. D., Tschiffely, A. E., McCarron, R. M., Hof, P. R., Gandy, S., Ahlers, S. T., & Elder, G. A. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.09.023 · Cited by 53
Animal Models of PTSD: The Socially Isolated Mouse and the Biomarker Role of Allopregnanolone
Pinna, G. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00114 · Cited by 52
Sexual Dysfunction in Veterans with Post-Traumatic Stress Disorder
Tran, J. K., Dunckel, G., & Teng, E. J. (2015) · The Journal of Sexual Medicine · doi:10.1111/jsm.12823 · Cited by 49
Dark-Enhanced Startle Responses and Heart Rate Variability in a Traumatized Civilian Sample
Kamkwalala, A. R., Norrholm, S. D., Poole, J. M., Brown, A. R., Donley, S., Duncan, E., Bradley, B., Ressler, K. J., & Jovanović, T. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318240803a · Cited by 52
Relationship of Hippocampal Volumes and Posttraumatic Stress Disorder Symptoms Over Early Posttrauma Periods
Xie, H., Claycomb Erwin, M., Elhai, J. D., Wall, J. T., Tamburrino, M. B., Brickman, K. R., Kaminski, B., McLean, S. A., Liberzon, I., & Wang, X. (2018) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2017.11.010 · Cited by 49
Self-citation
Neural circuits for the adaptive regulation of fear and extinction memory
Plas, S. L., Tuna, T., Bayer, H., Juliano, V. A. L., Sweck, S. O., Pérez, A. D. A., Hassell, J. E., & Maren, S. (2024) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2024.1352797 · Cited by 55
Acupuncture for Posttraumatic Stress Disorder: Conceptual, Clinical, and Biological Data Support Further Research
Hollifield, M. A. (2011) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2011.00241.x · Cited by 49
From Memory Impairment to Posttraumatic Stress Disorder-Like Phenotypes: The Critical Role of an Unpredictable Second Traumatic Experience
Finsterwald, C., Steinmetz, A. B., Travaglia, A., & Alberini, C. M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0771-15.2015 · Cited by 50
Comparative effects of intranasal neuropeptide Y and HS014 in preventing anxiety and depressive-like behavior elicited by single prolonged stress
Sabban, E. L., Serova, L. I., Alaluf, L. G., Lauková, M., & Peddu, C. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.12.038 · Cited by 47

Authors: Liberzon, I., & Sripada, C. S.
Affiliations: University of Michigan (US)
Corresponding author: Liberzon, Israel
ORCID: Liberzon, Israel
Sripada, Chandra Sekhar
Venue: Progress in Brain Research
Publisher: Elsevier
Published: 2007
Volume: 167
Pages: 151-169
ISSN: 0079-6123 (ISSN-L)
DOI: 10.1016/s0079-6123(07)67011-3
OpenAlex: W1564331199
Cited by: 594
References: 71
Citations by year: 2026: 11 · 2025: 17 · 2024: 17 · 2023: 20 · 2022: 21 · 2021: 33 · 2020: 45 · 2019: 24 · 2018: 42 · 2017: 37 · 2016: 46 · 2015: 37 · 2014: 46 · 2013: 42 · 2012: 43
FWCI: 91.41
Type: book chapter
Language: en
Open access: closed
Locations: Progress in brain research (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
Keywords: post-traumatic stress disorder, functional neuroanatomy, medial prefrontal cortex, amygdala, hippocampus, fear conditioning, habituation, extinction, cognitive-emotional interaction, social-emotional processing, contextualization, emotional dysregulation
MeSH terms: Animals, Cognition, Humans, Magnetic Resonance Imaging, Stress Disorders, Post-Traumatic, Prefrontal Cortex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The functional neuroanatomy of PTSD: a critical review

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks