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Crystal Structure of a Tyrosine Phosphorylated STAT-1 Dimer Bound to DNA
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Cites
Function and Activation of NF-kappaB in the Immune System
Baeuerle, P. A., & Henkel, T. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.001041 · Cited by 4,745
Protein Structure Comparison by Alignment of Distance Matrices
Holm, L., & Sander, C. (1993) · Journal of Molecular Biology · doi:10.1006/jmbi.1993.1489 · Cited by 3,984
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
Cho, Y., Gorina, S., Jeffrey, P. D., & Pavletich, N. P. (1994) · Science · doi:10.1126/science.8023157 · Cited by 2,551
Protein modules and signalling networks
Pawson, T. (1995) · Nature · doi:10.1038/373573a0 · Cited by 2,420
Shuai, K., Horvath, C. M., Huang, L. H. T., Qureshi, S. A., Cowburn, D., & Darnell, J. E. (1994) · Cell · doi:10.1016/0092-8674(94)90357-3 · Cited by 807
Components of a stat recognition code: Evidence for two layers of molecular selectivity
Schindler, U., Wu, P., Rothe, M., Brasseur, M., & McKnight, S. L. (1995) · Immunity · doi:10.1016/1074-7613(95)90013-6 · Cited by 246
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Interferon-γ: an overview of signals, mechanisms and functions
Schroder, K., Hertzog, P. J., Ravasi, T., & Hume, D. A. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0603252 · Cited by 4,120
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
HEINRICH, P. C., BEHRMANN, I., HAAN, S., HERMANNS, H. M., MÜLLER-NEWEN, G., & SCHAPER, F. (2003) · Biochemical Journal · doi:10.1042/bj20030407 · Cited by 3,272
STATs: transcriptional control and biological impact
Levy, D. E., & Darnell, J. E. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm909 · Cited by 3,201
Bromberg, J. F., Wrzeszczynska, M. H., Devgan, G., Zhao, Y., Pestell, R. G., Albanese, C., & Darnell, J. E. (1999) · Cell · doi:10.1016/s0092-8674(00)81959-5 · Cited by 2,790
Self-citationThe JAK/STAT signaling pathway: from bench to clinic
Hu, X., li, J., Fu, M., Zhao, X., & Wang, W. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00791-1 · Cited by 2,633
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
HEINRICH, P. C., BEHRMANN, I., MÜLLER-NEWEN, G., SCHAPER, F., & GRAEVE, L. (1998) · Biochemical Journal · doi:10.1042/bj3340297 · Cited by 2,130
Bowman, T., Garcia, R., Turkson, J., & Jove, R. (2000) · Oncogene · doi:10.1038/sj.onc.1203527 · Cited by 1,743
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
Schwartz, D. M., Kanno, Y., Villarino, A., Ward, M., Gadina, M., & O'Shea, J. J. (2017) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.201 · Cited by 1,266
The role of STATs in transcriptional control and their impact on cellular function
Bromberg, J., & Darnell, J. E. (2000) · Oncogene · doi:10.1038/sj.onc.1203476 · Cited by 1,201
The molecular details of cytokine signaling via the JAK/STAT pathway
Morris, R., Kershaw, N. J., & Babon, J. J. (2018) · Protein Science · doi:10.1002/pro.3519 · Cited by 943
Stat3 Dimerization Regulated by Reversible Acetylation of a Single Lysine Residue
Yuan, Z.-L., Guan, Y.-J., Chatterjee, D., & Chin, Y. E. (2005) · Science · doi:10.1126/science.1105166 · Cited by 790
Hillmer, E. J., Zhang, H., Li, H. S., & Watowich, S. S. (2016) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2016.05.001 · Cited by 740
Yasukawa, H., Misawa, H., Sakamoto, H., Masuhara, M., Sasaki, A., Wakioka, T., Ohtsuka, S., Imaizumi, T., Matsuda, T., Ihle, J. N., et al. (1999) · The EMBO Journal · doi:10.1093/emboj/18.5.1309 · Cited by 719
The Stat family in cytokine signaling
Ihle, J. N. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00199-x · Cited by 713
STAT proteins: novel molecular targets for cancer drug discovery
Turkson, J., & Jove, R. (2000) · Oncogene · doi:10.1038/sj.onc.1204086 · Cited by 643
Biology and significance of the JAK/STAT signalling pathways
Kiu, H., & Nicholson, S. E. (2012) · Growth Factors · doi:10.3109/08977194.2012.660936 · Cited by 470
Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation
Yang, J., Chatterjee-Kishore, M., Staugaitis, S. M., Nguyen, H., Schlessinger, K., Levy, D. E., & Stark, G. R. (2005) · Cancer Research · doi:10.1158/0008-5472.939.65.3 · Cited by 405
Sasaki, A., Yasukawa, H., Suzuki, A., Kamizono, S., Syoda, T., Kinjyo, I., Sasaki, M., Johnston, J. A., & Yoshimura, A. (1999) · Genes to Cells · doi:10.1046/j.1365-2443.1999.00263.x · Cited by 398
Modulation of STAT signaling by STAT-interacting proteins
Shuai, K. (2000) · Oncogene · doi:10.1038/sj.onc.1203522 · Cited by 379
Reich, N. C., & Liu, L. (2006) · Nature Reviews Immunology · doi:10.1038/nri1885 · Cited by 376
DNA Binding Specificity of Different STAT Proteins
Ehret, G. B., Reichenbach, P., Schindler, U., Horvath, C. M., Fritz, S., Nabholz, M., & Bucher, P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m001748200 · Cited by 369
Roles of unphosphorylated STATs in signaling
Yang, J., & Stark, G. R. (2008) · Cell Research · doi:10.1038/cr.2008.41 · Cited by 347
Regulated nuclear import of the STAT1 transcription factor by direct binding of importin‐α
McBride, K. M., Banninger, G., McDonald, C., & Reich, N. C. (2002) · The EMBO Journal · doi:10.1093/emboj/21.7.1754 · Cited by 289
Shen, Y., Devgan, G., Darnell, J. E., & Bromberg, J. F. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1543 · Cited by 249
Self-citationA molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription
Platanitis, E., Demiroz, D., Schneller, A., Fischer, K., Capelle, C., Hartl, M., Gossenreiter, T., Müller, M., Novatchkova, M., & Decker, T. (2019) · Nature Communications · doi:10.1038/s41467-019-10970-y · Cited by 233
STAT signaling in the pathogenesis and treatment of leukemias
Lin, T. S., Mahajan, S., & Frank, D. A. (2000) · Oncogene · doi:10.1038/sj.onc.1203486 · Cited by 205
The intrinsic substrate specificity of the human tyrosine kinome
Yaron-Barir, T. M., Joughin, B. A., Huntsman, E. M., Kerelsky, A., Cizin, D. M., Cohen, B. M., Regev, A., Song, J., Vasan, N., Lin, T.-Y., et al. (2024) · Nature · doi:10.1038/s41586-024-07407-y · Cited by 189
Fagerlund, R., Melén, K., Kinnunen, L., & Julkunen, I. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202943200 · Cited by 183
Babon, J. J., McManus, E. J., Yao, S., DeSouza, D. P., Mielke, L. A., Sprigg, N. S., Willson, T. A., Hilton, D. J., Nicola, N. A., Baca, M., et al. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.03.024 · Cited by 163
DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1
Meyer, T., Marg, A., Lemke, P., Wiesner, B., & Vinkemeier, U. (2003) · Genes & Development · doi:10.1101/gad.268003 · Cited by 161
“Guided by the Stat1–DNA cocrystal structure (Chen et al. 1998), we mutated residues in the DNAbinding domain that potentially make backbone contacts with phosphate groups in the DNA and are not part of the dsNLS (Fig.”
MethodSelf-citationLoops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets
Kaneko, T., Huang, H., Zhao, B., Li, L., Liu, H., Voss, C. K., Wu, C., Schiller, M. R., & Li, S. S.-C. (2010) · Science Signaling · doi:10.1126/scisignal.2000796 · Cited by 146
Zhang, T., Kee, W. H., Seow, K. T., Fung, W., & Cao, X. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.19.7132-7139.2000 · Cited by 150
Haftchenary, S., Luchman, H. A., Jouk, A. O., Veloso, A. J., Page, B. D. G., Cheng, X. R., Dawson, S. S., Grinshtein, N., Shahani, V. M., Kerman, K., et al. (2013) · ACS Medicinal Chemistry Letters · doi:10.1021/ml4003138 · Cited by 126
A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation
Ma, J., Zhang, T., Novotny-Diermayr, V., Tan, A. L. C., & Cao, X. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304196200 · Cited by 110
Hayakawa, F., Sugimoto, K., Harada, Y., Hashimoto, N., Ohi, N., Kurahashi, S., & Naoe, T. (2013) · Blood Cancer Journal · doi:10.1038/bcj.2013.63 · Cited by 108
Weerasinghe, P., Garcia, G., Zhu, Q., Yuan, P., Feng, L., Mao, L., & Jing, N. (2007) · International Journal of Oncology · doi:10.3892/ijo.31.1.129 · Cited by 95
IL-6 signaling via the STAT3/SOCS3 pathway: functional analysis of the conserved STAT3 N-domain
Zhang, L., Badgwell, D. B., Bevers, J. J., Schlessinger, K., Murray, P. J., Levy, D. E., & Watowich, S. S. (2006) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-006-9137-3 · Cited by 89
Dissociation Time from DNA Determines Transcriptional Function in a STAT1 Linker Mutant
Yang, E., Henriksen, M. A., Schaefer, O., Zakharova, N., & Darnell, J. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m112038200 · Cited by 88
Anti-DNA autoantibodies and systemic lupus erythematosus
Blatt, N. B., & Glick, G. D. (1999) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(99)00022-4 · Cited by 60
Mertens, C., Haripal, B., Klinge, S., & Darnell, J. E. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1515876112 · Cited by 59
Self-citationDesign of Conditionally Active STATs: Insights into STAT Activation and Gene Regulatory Function
Milocco, L. H., Haslam, J. A., Rosen, J., & Seidel, H. M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.4.2913 · Cited by 52
Metadata
- Authors
- Chen, X., Vinkemeier, U., Zhao, Y., Jeruzalmi, D., Darnell, J. E., & Kuriyan, J.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1998-05
- Volume
- 93
- Issue
- 5
- Pages
- 827-839
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2052982889
- Cited by
- 720
- References
- 6
- FWCI
- 18.71
- Type
- journal article
- Language
- en
- Open access
- bronze
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