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Obesity, cigarette smoking, and telomere length in women
Abstract
Obesity and smoking are important risk factors for many age-related diseases. Both are states of heightened oxidative stress, which increases the rate of telomere erosion per replication, and inflammation, which enhances white blood cell turnover. Together, these processes might accelerate telomere erosion with age. We therefore tested the hypothesis that increased body mass and smoking are associated with shortened telomere length in white blood cells. We investigated 1122 white women aged 18-76 years and found that telomere length decreased steadily with age at a mean rate of 27 bp per year. Telomeres of obese women were 240 bp shorter than those of lean women (p=0.026). A dose-dependent relation with smoking was recorded (p=0.017), and each pack-year smoked was equivalent to an additional 5 bp of telomere length lost (18%) compared with the rate in the overall cohort. Our results emphasise the pro-ageing effects of obesity and cigarette smoking.
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“Because LTL is also affected by other risk factors for CAD such as oxidative stress27–29, it has been unclear whether the association of shorter LTL with CAD is primary or secondary.”
From Identification of seven loci affecting mean telomere length and their association with disease (2013) · cites this paper as [28]
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Cites
Inflammation: the link between insulin resistance, obesity and diabetes
Dandona, P. (2004) · Trends in Immunology · doi:10.1016/j.it.2003.10.013 · Cited by 2,170
Telomere Length as an Indicator of Biological Aging
Bénétos, A., Okuda, K., Lajemi, M., Kimura, M., Thomas, F., Skurnick, J., Labat, C., Bean, K., & Aviv, A. (2001) · Hypertension · doi:10.1161/01.hyp.37.2.381 · Cited by 627
Self-citationAndrew, T., Hart, D. J., Snieder, H., de Lange, M., Spector, T. D., & MacGregor, A. J. (2001) · Twin Research · doi:10.1375/1369052012803 · Cited by 440
Self-citationOxidative stress and smoking-induced vascular injury
Burke, A., & FitzGerald, G. A. (2003) · Progress in Cardiovascular Diseases · doi:10.1016/s0033-0620(03)00076-8 · Cited by 277
Telomeres and human aging: facts and fibs
Aviv, A. (2004) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2004.51.pe43 · Cited by 198
Self-citationBełtowski, J. (2003) · Atherosclerosis · doi:10.1016/s0021-9150(03)00236-3 · Cited by 168
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Codd, V., Denniff, M. J., Swinfield, C., Warner, S., Papakonstantinou, M., Sheth, S., Nanus, D. E., Budgeon, C. A., Musicha, C., Bountziouka, V., et al. (2022) · Nature Aging · doi:10.1038/s43587-021-00166-9 · Cited by 242
Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length
Entringer, S., Epel, E. S., Lin, J., Buß, C., Shahbaba, B., Blackburn, E. H., Simhan, H. N., & Wadhwa, P. D. (2012) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2012.11.033 · Cited by 257
Mirabello, L. J., Huang, W., Wong, J. Y. Y., Chatterjee, N., Reding, D. J., Crawford, E. D., Vivo, I. D., Hayes, R. B., & Savage, S. A. (2009) · Aging Cell · doi:10.1111/j.1474-9726.2009.00485.x · Cited by 251
Health Inequality - determinants and policies
Diderichsen, F., Andersen, I., Manuel, C., The Working Group of the Danish Review on Social Determinants of Health, Andersen, A.-M. N., Bach, E., Baadsgaard, M., Brønnum-Hansen, H., Hansen, F. K., Jeune, B., et al. (2012) · Scandinavian Journal of Public Health · doi:10.1177/1403494812457734 · Cited by 247
Association of Telomere Length With Risk of Disease and Mortality
Schneider, C. V., Schneider, K. M., Teumer, A., Rudolph, K. L., Hartmann, D., Rader, D. J., & Strnad, P. (2022) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2021.7804 · Cited by 251
No Association Between Telomere Length and Survival Among the Elderly and Oldest Old
Bischoff, C., Petersen, H. C., Graakjær, J., Andersen‐Ranberg, K., Vaupel, J. W., Bohr, V. A., Kølvraa, S., & Christensen, K. (2006) · Epidemiology · doi:10.1097/01.ede.0000199436.55248.10 · Cited by 243
Basic Biology of Oxidative Stress and the Cardiovascular System
Sack, M. N., Fyhrquist, F., Saijonmaa, O. J., Fuster, V., & Kovacic, J. C. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.05.034 · Cited by 248
Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women
Richards, J. B., Valdes, A. M., Gardner, J. P., Paximadas, D., Kimura, M., Nessa, A., Lu, X., Surdulescu, G. L., Swaminathan, R., Spector, T. D., et al. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1420 · Cited by 237
Self-citationTelomere Biology and Cardiovascular Disease
Fuster, J. J., & Andrés, V. (2006) · Circulation Research · doi:10.1161/01.res.0000251281.00845.18 · Cited by 239
The UK Adult Twin Registry (TwinsUK)
Spector, T. D., & Williams, F. M. K. (2006) · Twin Research and Human Genetics · doi:10.1375/twin.9.6.899 · Cited by 237
Self-citationMoffitt, T. E., & Tank, T. K.-G. 2. T. (2013) · Development and Psychopathology · doi:10.1017/s0954579413000801 · Cited by 263
Tracking and fixed ranking of leukocyte telomere length across the adult life course
Benetos, A., Kark, J. D., Susser, E., Kimura, M., Sinnreich, R., Chen, W., Steenstrup, T., Christensen, K., Herbig, U., von Bornemann Hjelmborg, J., et al. (2013) · Aging Cell · doi:10.1111/acel.12086 · Cited by 223
Self-citationDarrow, S. M., Verhoeven, J. E., Révész, D., Lindqvist, D., Penninx, B. W. J. H., Delucchi, K. L., Wolkowitz, O. M., & Mathews, C. A. (2016) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000356 · Cited by 229
Mangino, M., Hwang, S., Spector, T. D., Hunt, S. C., Kimura, M., Fitzpatrick, A. L., Christiansen, L., Petersen, I., Elbers, C. C., Harris, T. B., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds382 · Cited by 228
Self-citationEstimating telomere length from whole genome sequence data
Ding, Z., Mangino, M., Aviv, A., Spector, T. D., & Durbin, R. M. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku181 · Cited by 224
Self-citationRole of visceral adipose tissue in aging
Huffman, D. M., & Barzilai, N. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.01.008 · Cited by 220
Race/ethnicity and telomere length in the Multi‐Ethnic Study of Atherosclerosis
Roux, A. V. D., Ranjit, N., Jenny, N. S., Shea, S., Cushman, M., Fitzpatrick, A. L., & Seeman, T. E. (2009) · Aging Cell · doi:10.1111/j.1474-9726.2009.00470.x · Cited by 220
Telomere Dynamics in Mice and Humans
Calado, R. T., & Dumitriu, B. (2013) · Seminars in Hematology · doi:10.1053/j.seminhematol.2013.03.030 · Cited by 214
The Rate of Increase of Short Telomeres Predicts Longevity in Mammals
Vera, E., de Jesus, B. B., Foronda, M., Flores, J. M., & Blasco, M. A. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.08.023 · Cited by 228
Dynamics of telomerase activity in response to acute psychological stress
Epel, E. S., Lin, J., Dhabhar, F. S., Wolkowitz, O. M., Puterman, E. M., Karan, L. D., & Blackburn, E. H. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.11.018 · Cited by 224
Starkweather, A. R., Alhaeeri, A. A., Montpetit, A. J., Brumelle, J., Filler, K., Montpetit, M., Mohanraj, L., Lyon, D., & Jackson‐Cook, C. K. (2013) · Nursing Research · doi:10.1097/nnr.0000000000000009 · Cited by 225
Combined Toxic Exposures and Human Health: Biomarkers of Exposure and Effect
Silins, I., & Högberg, J. (2011) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph8030629 · Cited by 217
Inverse association between adiposity and telomere length: The fels longitudinal study
Lee, M., Martin, H. B., Firpo, M. A., & Demerath, E. W. (2010) · American Journal of Human Biology · doi:10.1002/ajhb.21109 · Cited by 213
A ‘higher order’ of telomere regulation: telomere heterochromatin and telomeric RNAs
Schoeftner, S., & Blasco, M. A. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.197 · Cited by 232
CHEN, W., Kimura, M., Kim, S., Cao, X., Srinivasan, S. R., Berenson, G. S., Kark, J. D., & Aviv, A. (2011) · The Journals of Gerontology Series A · doi:10.1093/gerona/glq223 · Cited by 211
Self-citationA living model for obesity and aging research: Caenorhabditis elegans
Shen, P., Yue, Y., & Park, Y. (2016) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2016.1220914 · Cited by 220
Hallmarks of telomeres in ageing research
Shay, J., & Wright, W. E. (2007) · The Journal of Pathology · doi:10.1002/path.2090 · Cited by 211
Telomere length and the risk of lung cancer
Jang, J. S., Choi, Y. Y., Lee, W. K., Choi, J. E., Ick, S., Kim, Y. J., Kim, C. H., Kam, S., Jung, T. H., & Park, J. Y. (2008) · Cancer Science · doi:10.1111/j.1349-7006.2008.00831.x · Cited by 207
Effect of obesity on telomere length: Systematic review and meta-analysis
Mundstock, E., Sarria, E. E., Zatti, H., Louzada, F. M., Grün, L. K., Jones, M. H., Guma, F. T. C. R., Memoriam, J. M. I., Epifânio, M., Stein, R. T., et al. (2015) · Obesity · doi:10.1002/oby.21183 · Cited by 216
The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia
Hsiung, C. A., Lan, Q., Hong, Y., Chen, C., Hosgood, H. D., Chang, I., Chatterjee, N., Brennan, P., Wu, C. H., Zheng, W., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001051 · Cited by 211
Eisenberg, D. T. A. (2010) · American Journal of Human Biology · doi:10.1002/ajhb.21127 · Cited by 215
Bana, B., & Cabreiro, F. (2019) · Annual Review of Genetics · doi:10.1146/annurev-genet-112618-043650 · Cited by 212
Farzaneh-Far, R., Lin, J., Epel, E., Lapham, K., Blackburn, E., & Whooley, M. A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008612 · Cited by 203
Update in genetic susceptibility in melanoma.
Potrony, M., Bádenas, C., Aguilera, P., Puig‐Butillé, J. A., Carrera, C., Malvehy, J., & Puig, S. (2015) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2305-5839.2015.08.11 · Cited by 201
Harris, S. E., Deary, I. J., MacIntyre, A., Lamb, K. J., Radhakrishnan, K., Starr, J. M., Whalley, L. J., & Shiels, P. G. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.07.055 · Cited by 200
The heritability of leucocyte telomere length dynamics
Hjelmborg, J., Dalgård, C., Möller, S., Steenstrup, T., Kimura, M., Christensen, K., Kyvik, K. O., & Aviv, A. (2015) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2014-102736 · Cited by 200
Self-citationTelomeres and Telomerase in Cardiovascular Diseases
Yeh, J., & Wang, C. (2016) · Genes · doi:10.3390/genes7090058 · Cited by 203
Luppi, F., Kalluri, M., Faverio, P., Kreuter, M., & Ferrara, G. (2021) · Respiratory Research · doi:10.1186/s12931-021-01711-1 · Cited by 211
Telomeres: Linking stress and survival, ecology and evolution
Haussmann, M. F., & Marchetto, N. M. (2010) · Current Zoology · doi:10.1093/czoolo/56.6.714 · Cited by 204
Multivitamin use and telomere length in women
Xu, Q., Parks, C. G., DeRoo, L. A., Cawthon, R., Sandler, D. P., & Chen, H. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26986 · Cited by 194
The fetal programming of telomere biology hypothesis: an update
Entringer, S., de Punder, K., Buß, C., & Wadhwa, P. D. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0151 · Cited by 194
Ehrlenbach, S., Willeit, P., Kiechl, S. J., Willeit, J., Reindl, M., Schanda, K., Kronenberg, F., & Kloss‐Brandstätter, A. (2009) · International Journal of Epidemiology · doi:10.1093/ije/dyp273 · Cited by 195
Obesity and Weight Gain in Adulthood and Telomere Length
Kim, S., Parks, C. G., DeRoo, L. A., Chen, H., Taylor, J. A., Cawthon, R., & Sandler, D. P. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0935 · Cited by 190
Tzanetakou, I. P., Katsilambros, N. L., Bénétos, A., Mikhailidis, & Perrea, D. N. (2011) · Ageing Research Reviews · doi:10.1016/j.arr.2011.12.003 · Cited by 193
Ageing and the border between health and disease
MacNee, W., Rabinovich, R., & Choudhury, G. (2014) · European Respiratory Journal · doi:10.1183/09031936.00134014 · Cited by 198
Maternal pre-pregnancy body mass index and newborn telomere length
Martens, D. S., Plusquin, M., Gyselaers, W., Vivo, I. D., & Nawrot, T. S. (2016) · BMC Medicine · doi:10.1186/s12916-016-0689-0 · Cited by 189
Mediterranean Diet, Telomere Maintenance and Health Status among Elderly
Boccardi, V., Esposito, A., Rizzo, M. R., Marfella, R., Barbieri, M., & Paolisso, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062781 · Cited by 189
Telomere Length Is Associated With Obesity Parameters but With a Gender Difference
Nordfjäll, K., Eliasson, M., Stegmayr, B., Melander, O., Nilsson, P. M., & Roos, G. (2008) · Obesity · doi:10.1038/oby.2008.413 · Cited by 188
Prognostic Value of Leukocyte Telomere Length in Patients With Stable Coronary Artery Disease
Farzaneh‐Far, R., Cawthon, R., Na, B., Browner, W. S., Schiller, N. B., & Whooley, M. A. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.167049 · Cited by 194
Wilson, W. R. W., Herbert, K. E., Mistry, Y., Stevens, S. E., Patel, H. R., Hastings, R. A., Thompson, M. M., & Williams, B. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn386 · Cited by 185
Nettleton, J. A., Diez-Roux, A., Jenny, N. S., Fitzpatrick, A. L., & Jacobs, D. R. (2008) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26429 · Cited by 184
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Du, M., Prescott, J., Kraft, P. L., Han, J., Giovannucci, E. L., Hankinson, S. E., & Vivo, I. D. (2012) · American Journal of Epidemiology · doi:10.1093/aje/kwr330 · Cited by 182
Ageing, telomeres, senescence, and liver injury
Hoare, M., Das, T., & Alexander, G. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.06.009 · Cited by 184
Ryan, J. L., Wrigglesworth, J., Loong, J., Fransquet, P., & Woods, R. L. (2019) · The Journals of Gerontology Series A · doi:10.1093/gerona/glz099 · Cited by 178
Early vascular aging (EVA): consequences and prevention
Nilsson, P. M. (2008) · Vascular Health and Risk Management · doi:10.2147/vhrm.s1094 · Cited by 188
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Aerobic fitness is associated with lower proportions of senescent blood T-cells in man
Spielmann, G., McFarlin, B. K., O’Connor, D. P., Smith, P. J. W., Pircher, H., & Simpson, R. J. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2011.07.226 · Cited by 180
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Han, J., Qureshi, A. A., Prescott, J., Guo, Q., Ye, L., Hunter, D. J., & Vivo, I. D. (2008) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.238 · Cited by 175
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Parks, C. G., Miller, D. B., McCanlies, E. C., Cawthon, R., Andrew, M. E., DeRoo, L. A., & Sandler, D. P. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0614 · Cited by 176
Theall, K. P., Brett, Z. H., Shirtcliff, E. A., Dunn, E. C., & Drury, S. S. (2013) · Social Science & Medicine · doi:10.1016/j.socscimed.2013.02.030 · Cited by 175
van der Weerd, K., Dik, W. A., Schrijver, B., Schweitzer, D. H., Langerak, A. W., Drexhage, H. A., Kiewiet, R. M., van Aken, M. O., van Huisstede, A., van Dongen, J. J. M., et al. (2012) · Diabetes · doi:10.2337/db11-1065 · Cited by 180
Angelier, F., Costantini, D., Blévin, P., & Chastel, O. (2017) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2017.07.007 · Cited by 174
Telomere length loss due to smoking and metabolic traits
Huzen, J., Wong, L. S. M., van Veldhuisen, D. J., Samani, N. J., Zwinderman, A. H., Codd, V., Cawthon, R., Benus, G. F. J. D., van der Horst, I. C. C., Navis, G. J., et al. (2013) · Journal of Internal Medicine · doi:10.1111/joim.12149 · Cited by 177
Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals
Nevalainen, T., Kananen, L., Marttila, S., Jylhävä, J., Mononen, N., Kähönen, M. A. P., Raitakari, O. T., Hervonen, A., Jylhä, M. K., Lehtimäki, T. J., et al. (2017) · Clinical Epigenetics · doi:10.1186/s13148-016-0301-7 · Cited by 173
Gielen, M., Hageman, G. J., Antoniou, E. E., Nordfjäll, K., Mangino, M., Balasubramanyam, M., Meyer, T. D., Hendricks, A. E., Giltay, E. J., Hunt, S. C., et al. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy107 · Cited by 175
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Müller, K., Welker, L., Paasch, K., Feindt, B., Erpenbeck, V., Hohlfeld, J. M., Krug, N., Nakashima, M., Branscheid, D., MAGNUSSEN, H., et al. (2006) · Respiratory Research · doi:10.1186/1465-9921-7-32 · Cited by 173
Human telomere biology: pitfalls of moving from the laboratory to epidemiology
Aviv, A., Valdes, A. M., & Spector, T. D. (2006) · International Journal of Epidemiology · doi:10.1093/ije/dyl169 · Cited by 172
Self-citationGeiger, S., Vaillant, M. L., Lebard, T., Reichert, S., Stier, A., Maho, Y. L., & Criscuolo, F. (2011) · Molecular Ecology · doi:10.1111/j.1365-294x.2011.05331.x · Cited by 172
Valdes, A. M., Richards, J. B., Gardner, J. P., Swaminathan, R., Kimura, M., Xiaobin, L., Aviv, A., & Spector, T. D. (2007) · Osteoporosis International · doi:10.1007/s00198-007-0357-5 · Cited by 164
Self-citationShortened telomeres in individuals with abuse in alcohol consumption
Pavanello, S., Hoxha, M., Dioni, L., Bertazzi, P. A., Snenghi, R., Nalesso, A., Ferrara, S. D., Montisci, M., & Baccarelli, A. (2011) · International Journal of Cancer · doi:10.1002/ijc.25999 · Cited by 167
Aviv, A., Valdes, A. M., Gardner, J. P., Swaminathan, R., Kimura, M., & Spector, T. D. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1814 · Cited by 167
Self-citationRationale, design, methods and baseline characteristics of the Asklepios Study
Rietzschel, E., Buyzere, M. D., Bekaert, S., Segers, P., Bacquer, D. D., Cooman, L., Damme, P. V., Cassiman, P., Langlois, M. R., Oostveldt, P. V., et al. (2007) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e328012c380 · Cited by 167
Song, Z., Von Figura, G., Liu, Y., Kraus, J. M., Torrice, C., Dillon, P., Rudolph‐Watabe, M., Ju, Z., Kestler, H. A., Sanoff, H., et al. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00583.x · Cited by 163
Yaffe, K. S., Lindquist, K. J., Kluse, M., Cawthon, R., Harris, T. B., Hsueh, W.-C., Simonsick, E. M., Kuller, L. H., Li, R., Ayonayon, H. N., et al. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.12.006 · Cited by 164
Healthy aging and disease: role for telomere biology?
Zhu, H., Belcher, M. D., & van der Harst, P. (2011) · Clinical Science · doi:10.1042/cs20100385 · Cited by 169
Zhu, H., Wang, X., Gutin, B., Davis, C. L., Keeton, D., Thomas, J. D., Stallmann-Jorgensen, I. S., Mooken, G., Bundy, V. L., Snieder, H., et al. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.08.007 · Cited by 162
Zhao, J., Zhu, Y., Lin, J., Matsuguchi, T., Blackburn, E., Zhang, Y., Cole, S. A., Best, L. G., Lee, E. T., & Howard, B. V. (2014) · Diabetes · doi:10.2337/db13-0744 · Cited by 161
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Pooley, K. A., Sandhu, M. S., Tyrer, J. P., Shah, M., Driver, K. E., Luben, R., Bingham, S. A., Ponder, B. A. J., Pharoah, P. D. P., Khaw, K., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4595 · Cited by 161
Daubenmier, J., Lin, J., Blackburn, E., Hecht, F. M., Kristeller, J., Maninger, N., Kuwata, M., Bacchetti, P., Havel, P. J., & Epel, E. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.10.008 · Cited by 157
Hou, L., Wang, S., Chang, D., Zhang, X., Yu, Y., Zheng, Y., Avula, U., Hoxha, M., Díaz-Artiga, A., McCracken, J., et al. (2012) · Environment International · doi:10.1016/j.envint.2012.06.020 · Cited by 160
Prenatal stress and newborn telomere length
Marchetto, N. M., Glynn, R. A., Ferry, M. L., Ostojic, M., Wolff, S. M., Yao, R., & Haussmann, M. F. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.01.177 · Cited by 161
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Shen, J., Terry, M. B., Gurvich, I., Liao, Y., Senie, R. T., & Santella, R. M. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3490 · Cited by 157
Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool
van de Berg, P. J. E. J., Griffiths, S. J., Yong, S.-L., Macaulay, R., Bemelman, F. J., Jackson, S., Henson, S. M., ten Berge, I. J. M., Akbar, A. N., & van Lier, R. A. W. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903442 · Cited by 157
Human diseases of telomerase dysfunction: insights into tissue aging
Garcia, C. K., Wright, W. E., & Shay, J. W. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm644 · Cited by 161
Telomere length reflects phenotypic quality and costs of reproduction in a long-lived seabird
Bauch, C., Becker, P. H., & Verhulst, S. (2012) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2012.2540 · Cited by 157
Telomerase, senescence and ageing
Shawi, M., & Autexier, C. (2008) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2007.11.007 · Cited by 160
Hoxha, M., Dioni, L., Bonzini, M., Pesatori, A. C., Fustinoni, S., Cavallo, D. M., Carugno, M., Albetti, B., Marinelli, B., Schwartz, J. D., et al. (2009) · Environmental Health · doi:10.1186/1476-069x-8-41 · Cited by 156
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Zhu, X., Han, W., Xue, W., Zou, Y., Xie, C., Du, J., & Jin, G. (2016) · Scientific Reports · doi:10.1038/srep22243 · Cited by 146
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Moslehi, J. J., DePinho, R. A., & Sahin, E. (2012) · Circulation Research · doi:10.1161/circresaha.111.246868 · Cited by 154
Pavanello, S., Pesatori, A. C., Dioni, L., Hoxha, M., Bollati, V., Siwińska, E., Mielżyńska, D., Bolognesi, C., Bertazzi, P. A., & Baccarelli, A. (2009) · Carcinogenesis · doi:10.1093/carcin/bgp278 · Cited by 148
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Buxton, J. L., Walters, R. G., Visvikis‐Siest, S., Meyre, D., Froguel, P., & Blakemore, A. I. F. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2924 · Cited by 148
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Metadata
- Authors
- Valdes, A., Andrew, T., Gardner, J., Kimura, M., Oelsner, E., Cherkas, L., Aviv, A., & Spector, T.
- Affiliations
- St Thomas' Hospital (GB)
- University of Medicine and Dentistry of New Jersey (US)
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2005-08
- Volume
- 366
- Issue
- 9486
- Pages
- 662-664
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2147991226
- Cited by
- 1,363
- References
- 6
- Citations by year
- 2026: 19 · 2025: 25 · 2024: 46 · 2023: 47 · 2022: 59 · 2021: 63 · 2020: 65 · 2019: 81 · 2018: 62 · 2017: 80 · 2016: 89 · 2015: 75 · 2014: 98 · 2013: 80 · 2012: 100
- FWCI
- 29.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Rutgers University Community Repository (Rutgers University) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- Healthcare Foundation of New Jersey
- Grant Healthcare Foundation
- Wellcome Trust
- Korea Institute of Machinery and Materials
- National Institutes of Health
- National Institute on Aging (R01AG021593, AG021593)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Keywords
- obesity, cigarette smoking, telomere length, leukocytes, oxidative stress, inflammation, aging, pack-years, women, body mass index
- MeSH terms
- Adolescent, Adult, Aged, Aging, Female, Humans, Middle Aged, Obesity, Risk Factors, Smoking, Telomere
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