Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study
Open accessAbstract
Background Psychological distress and metabolic dysregulation are associated with markers of accelerated cellular aging, including reduced telomerase activity and shortened telomere length. We examined whether participation in a mindfulness-based intervention, and, secondarily, improvements in psychological distress, eating behavior, and metabolic factors are associated with increases in telomerase activity in peripheral blood mononuclear cells (PBMCs).Methods We enrolled 47 overweight/obese women in a randomized waitlist-controlled pilot trial (n=47) of a mindfulness-based intervention for stress eating and examined changes in telomerase activity from pre- to post-intervention. In secondary analyses, changes in telomerase activity across the sample were examined in relation to pre- to post-intervention changes in psychological distress, eating behavior, and metabolic factors (weight, serum cortisol, fasting glucose and insulin, and insulin resistance).Results Both groups increased in mean telomerase activity over 4 months in intent-to-treat and treatment efficacy analyses (p<0.001). Nonsignificant trends showed that greater attendance was associated with increases in telomerase, and telomerase increases were 18% higher among 'as treated' participants compared to controls. Across groups, changes in chronic stress, anxiety, dietary restraint, dietary fat intake, cortisol, and glucose were negatively correlated with changes in telomerase activity. In exploratory analyses, decreases in dietary fat intake partially mediated the association between dietary restraint and telomerase activity with marginal significance.Conclusions While there was no clear effect of the intervention on telomerase activity, there was a striking pattern of correlations between improvements in psychological distress, eating behavior, and metabolic health and increases in telomerase activity. These findings suggest that telomerase activity may be in part regulated by levels of both psychological and metabolic stress.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Findings on weight loss after mindfulness are mixed, with some studies but not all reporting weight improvements.
“Findings on weight loss after mindfulness have been mixed, with some31–37 but not all38,39 studies reporting improvements in weight.”
From A Mindfulness-Based Intervention to Control Weight After Bariatric Surgery: Preliminary Results From a Randomized Controlled Pilot Trial (2016) · cites this paper as [38]
In a study of overweight/obese women, a mindfulness intervention reduced anxiety but did not change PSS scores or chronic stress levels.
“A study among overweight/obese women found that anxiety levels decreased in the intervention group but PSS scores and levels of chronic stress did not change after a mindfulness intervention36.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Baron, R. M., & Kenny, D. A. (1986) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.51.6.1173 · Cited by 91,542 · see citing works
Baron, R. M., & Kenny, D. A. (1986) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.51.6.1173 · Cited by 91,532 · see citing works
A Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807 · see citing works
(1970) · Cited by 24,983 · see citing works
Use and Abuse of HOMA Modeling
Wallace, T. M., Levy, J. C., & Matthews, D. R. (2004) · Diabetes Care · doi:10.2337/diacare.27.6.1487 · Cited by 5,114 · see citing works
Accelerated telomere shortening in response to life stress
Epel, E. S., Blackburn, E. H., Lin, J., Dhabhar, F. S., Adler, N. E., Morrow, J. D., & Cawthon, R. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407162101 · Cited by 3,002 · see citing works
Self-citationAssessment of Mindfulness by Self-Report: The Kentucky Inventory of Mindfulness Skills
Baer, R. A., Smith, G. T., & Allen, K. B. (2004) · Assessment · doi:10.1177/1073191104268029 · Cited by 2,298 · see citing works
Association between telomere length in blood and mortality in people aged 60 years or older
Cawthon, R. M., Smith, K. R., O'Brien, E., Sivatchenko, A., & Kerber, R. A. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12384-7 · Cited by 1,761 · see citing works
Telomere states and cell fates
Blackburn, E. H. (2000) · Nature · doi:10.1038/35040500 · Cited by 1,372 · see citing works
Self-citationObesity, cigarette smoking, and telomere length in women
Valdes, A., Andrew, T., Gardner, J., Kimura, M., Oelsner, E., Cherkas, L., Aviv, A., & Spector, T. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66630-5 · Cited by 1,363 · see citing works
Telomere dysfunction induces metabolic and mitochondrial compromise
Sahin, E., Colla, S., Liesa, M., Moslehi, J., Müller, F. L., Guo, M., Cooper, M., Kotton, D., Fabian, A. J., Walkey, C., et al. (2011) · Nature · doi:10.1038/nature09787 · Cited by 1,319 · see citing works
(1990) · Cited by 1,282 · see citing works
Inflammation and cardiovascular disease mechanisms
Libby, P. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.2.456s · Cited by 1,095 · see citing works
Telomerase activity in normal and malignant hematopoietic cells.
Broccoli, D., Young, J. W., & de Lange, T. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.20.9082 · Cited by 752 · see citing works
An Exploratory Study of a Meditation-based Intervention for Binge Eating Disorder
Kristeller, J. L., & Hallett, C. B. (1999) · Journal of Health Psychology · doi:10.1177/135910539900400305 · Cited by 681 · see citing works
Self-citationNutritional, Dietary and Postprandial Oxidative Stress
Sies, H., Stahl, W., & Sevanian, A. (2005) · Journal of Nutrition · doi:10.1093/jn/135.5.969 · Cited by 608 · see citing works
Kristeller, J. L., & Wolever, R. Q. (2010) · Eating Disorders · doi:10.1080/10640266.2011.533605 · Cited by 592 · see citing works
Self-citationThe Association Between Physical Activity in Leisure Time and Leukocyte Telomere Length
Cherkas, L. F. (2008) · Archives of Internal Medicine · doi:10.1001/archinternmed.2007.39 · Cited by 568 · see citing works
Simon, N. M., Smoller, J. W., McNamara, K. L., Maser, R. S., Zalta, A. K., Pollack, M. H., Nierenberg, A. A., Fava, M., & Wong, K.-K. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.004 · Cited by 516 · see citing works
Wheaton, B. (1994) · Springer eBooks · doi:10.1007/978-1-4899-1106-3_4 · Cited by 469 · see citing works
Cell aging in relation to stress arousal and cardiovascular disease risk factors
Epel, E. S., Lin, J., Wilhelm, F. H., Wolkowitz, O. M., Cawthon, R., Adler, N. E., Dolbier, C., Mendes, W. B., & Blackburn, E. H. (2006) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2005.08.011 · Cited by 450 · see citing works
Self-citationIntensive meditation training, immune cell telomerase activity, and psychological mediators
Jacobs, T. L., Epel, E. S., Lin, J., Blackburn, E. H., Wolkowitz, O. M., Bridwell, D. A., Zanesco, A. P., Aichele, S. R., Sahdra, B. K., MacLean, K. A., et al. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.09.010 · Cited by 432 · cited 4× · see citing works
“The meditation group had higher postintervention telomerase than the waitlist control group, and increases in psychological well-being (increased perceived control and purpose in life and decreased negative affectivity) were related to higher post-intervention telomerase in the treatment but not control group (Jacobs…”
BackgroundInfluentialSelf-citationIncreased telomerase activity and comprehensive lifestyle changes: a pilot study
Ornish, D., Lin, J., Daubenmier, J., Weidner, G., Epel, E., Kemp, C., Magbanua, M. J. M., Marlin, R., Yglecias, L., Carroll, P. R., et al. (2008) · The Lancet Oncology · doi:10.1016/s1470-2045(08)70234-1 · Cited by 430 · see citing works
Self-citationLin, J., Epel, E., Cheon, J., Kroenke, C., Sinclair, E., Bigos, M., Wolkowitz, O., Mellon, S., & Blackburn, E. (2010) · Journal of Immunological Methods · doi:10.1016/j.jim.2009.09.012 · Cited by 426 · see citing works
Self-citationPsychological and metabolic stress: A recipe for accelerated cellular aging?
Epel, E. S. (2009) · HORMONES · doi:10.14310/horm.2002.1217 · Cited by 422 · see citing works
Self-citationDamjanovic, A. K., Yang, Y., Glaser, R., Kiecolt‐Glaser, J. K., Nguyen, H., Laskowski, B. F., Zou, Y., Beversdorf, D. Q., & Weng, N. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.6.4249 · Cited by 413 · see citing works
Regulated expression of telomerase activity in human T lymphocyte development and activation.
Weng, N., Levine, B. L., June, C. H., & Hodes, R. J. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.183.6.2471 · Cited by 403 · see citing works
Avison, W. R., & Gotlib, I. H. (1994) · Springer eBooks · doi:10.1007/978-1-4899-1106-3 · Cited by 401 · see citing works
Physical Exercise Prevents Cellular Senescence in Circulating Leukocytes and in the Vessel Wall
Werner, C., Fürster, T., Widmann, T., Pöss, J., Roggia, C., Hanhoun, M., Scharhag, J., Büchner, N., Meyer, T., Kindermann, W., et al. (2009) · Circulation · doi:10.1161/circulationaha.109.861005 · Cited by 380 · see citing works
Rise in Insulin Resistance Is Associated With Escalated Telomere Attrition
Gardner, J. P., Li, S., Srinivasan, S. R., Chen, W., Kimura, M., Lu, X., Berenson, G. S., & Aviv, A. (2005) · Circulation · doi:10.1161/01.cir.0000163550.70487.0b · Cited by 361 · see citing works
Reduced telomerase activity in human T lymphocytes exposed to cortisol
Choi, J., Fauce, S. R., & Effros, R. B. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.12.004 · Cited by 352 · see citing works
The power of exercise: buffering the effect of chronic stress on telomere length
Puterman, E., Lin, J., Blackburn, E., O'Donovan, A., Adler, N., & Epel, E. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010837 · Cited by 339 · see citing works
Self-citationO’Donovan, A., Pantell, M. S., Puterman, E. M., Dhabhar, F. S., Blackburn, E. H., Yaffe, K. S., Cawthon, R., Opresko, P. L., Hsueh, W.-C., Satterfield, S., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019687 · Cited by 338 · see citing works
Self-citationDaubenmier, J., Kristeller, J., Hecht, F. M., Maninger, N., Kuwata, M., Jhaveri, K., Lustig, R. H., Kemeny, M., Karan, L., & Epel, E. (2011) · Journal of Obesity · doi:10.1155/2011/651936 · Cited by 322 · cited 5× · see citing works
“Detailed methods adhering to the CONSORT guidelines are described in the parent study (Daubenmier et al., 2011).”
BackgroundMethodResultInfluentialSelf-citationTelomere length predicts survival independent of genetic influences
Bakaysa, S. L., Mucci, L. A., Slagboom, P. E., Boomsma, D. I., McClearn, G. E., Johansson, B. E. A., & Pedersen, N. L. (2007) · Aging Cell · doi:10.1111/j.1474-9726.2007.00340.x · Cited by 304 · see citing works
Telomere Length and Mortality: A Study of Leukocytes in Elderly Danish Twins
Kimura, M., Hjelmborg, J., Gardner, J. P., Bathum, L., Brimacombe, M. B., Lu, X., Christiansen, L., Vaupel, J. W., Aviv, A., & Christensen, K. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwm380 · Cited by 275 · see citing works
Telomere length predicts poststroke mortality, dementia, and cognitive decline
Martin-Ruiz, C. M., Dickinson, H. O., Keys, B., Rowan, E. N., Kenny, R. A., & von Zglinicki, T. (2006) · Annals of Neurology · doi:10.1002/ana.20869 · Cited by 257 · see citing works
Mirabello, L. J., Huang, W., Wong, J. Y. Y., Chatterjee, N., Reding, D. J., Crawford, E. D., Vivo, I. D., Hayes, R. B., & Savage, S. A. (2009) · Aging Cell · doi:10.1111/j.1474-9726.2009.00485.x · Cited by 246 · see citing works
Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women
Richards, J. B., Valdes, A. M., Gardner, J. P., Paximadas, D., Kimura, M., Nessa, A., Lu, X., Surdulescu, G. L., Swaminathan, R., Spector, T. D., et al. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1420 · Cited by 237 · see citing works
Diet, nutrition and telomere length
Paul, L. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.12.001 · Cited by 227 · see citing works
Dynamics of telomerase activity in response to acute psychological stress
Epel, E. S., Lin, J., Dhabhar, F. S., Wolkowitz, O. M., Puterman, E. M., Karan, L. D., & Blackburn, E. H. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.11.018 · Cited by 218 · see citing works
Self-citationDoes cellular aging relate to patterns of allostasis?
Tomiyama, A. J., O’Donovan, A., Lin, J., Puterman, E. M., Lazaro, A., Chan, J. L., Dhabhar, F. S., Wolkowitz, O. M., Kirschbaum, C., Blackburn, E. H., et al. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.11.016 · Cited by 206 · see citing works
Self-citationMultivitamin use and telomere length in women
Xu, Q., Parks, C. G., DeRoo, L. A., Cawthon, R., Sandler, D. P., & Chen, H. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26986 · Cited by 194 · see citing works
Telomeres and Cardiovascular Disease
Serrano, A. L., & Andrés, V. (2004) · Circulation Research · doi:10.1161/01.res.0000122141.18795.9c · Cited by 194 · see citing works
Nettleton, J. A., Diez-Roux, A., Jenny, N. S., Fitzpatrick, A. L., & Jacobs, D. R. (2008) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26429 · Cited by 184 · see citing works
Shorter telomeres are associated with mortality in those withAPOEϵ4 and dementia
Honig, L. S., Schupf, N., Lee, J. H., Tang, M. X., & Mayeux, R. P. (2006) · Annals of Neurology · doi:10.1002/ana.20894 · Cited by 177 · see citing works
Telomere Length, Current Perceived Stress, and Urinary Stress Hormones in Women
Parks, C. G., Miller, D. B., McCanlies, E. C., Cawthon, R., Andrew, M. E., DeRoo, L. A., & Sandler, D. P. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0614 · Cited by 176 · see citing works
Mean leukocyte telomere length shortening and type 2 diabetes mellitus: a case-control study
Zee, R. Y. L., Castonguay, A. J., Barton, N. S., Germer, S., & Martin, M. (2009) · Translational research · doi:10.1016/j.trsl.2009.09.012 · Cited by 169 · see citing works
Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy
Adaikalakoteswari, A., Balasubramanyam, M., Ravikumar, R., Deepa, R., & Mohan, V. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.12.003 · Cited by 156 · see citing works
Stress and Mental Health: Contemporary Issues and Prospects for the Future.
Tausig, M., Avison, W. R., & Gotlib, I. H. (1995) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2076727 · Cited by 144 · see citing works
Telomerase deficiency impairs glucose metabolism and insulin secretion
Kuhlow, D., Florian, S., von Figura, G., Weimer, S., Schulz, N., Petzke, K. J., Zarse, K., Pfeiffer, A. F. H., Rudolph, K. L., & Ristow, M. (2010) · Aging · doi:10.18632/aging.100200 · Cited by 129 · see citing works
Genetic pathway of major depressive disorder in shortening telomeric length
Lung, F., Chen, N. C., & Shu, B. (2007) · Psychiatric Genetics · doi:10.1097/ypg.0b013e32808374f6 · Cited by 118 · see citing works
Life events, emotional eating and change in body mass index.
van Strien, T., Rookus, M. A., Bergers, G. P. A., Frijters, J. E. R., & Defares, P. B. (1986) · PubMed · Cited by 109 · see citing works
Telomeres and immunological diseases of aging.
Andrews, N. P., Fujii, H., Goronzy, J. J., & Weyand, C. M. (2010) · Gerontology · doi:10.1159/000268620 · Cited by 108 · see citing works
Short Telomeres Compromise β-Cell Signaling and Survival
Guo, N., Parry, E. M., Li, L.-S., Kembou, F., Lauder, N., Hussain, M. A., Berggren, P.-O., & Armanios, M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017858 · Cited by 100 · see citing works
Telomerase induction in T cells: A cure for aging and disease?
Effros, R. B. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2006.11.005 · Cited by 82 · see citing works
Non-telomeric activities of telomerase
Majerská, J., Sýkorová, E., & Fajkus, J. (2011) · Molecular BioSystems · doi:10.1039/c0mb00268b · Cited by 46 · see citing works
Makino, N., Maeda, T., Oyama, J., Sasaki, M., Higuchi, Y., Mimori, K., & Shimizu, T. (2010) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2010.12.014 · Cited by 42 · see citing works
Dietary Restraint and Telomere Length in Pre- and Postmenopausal Women
Kiefer, A. K., Lin, J., Blackburn, E. H., & Epel, E. S. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318187d05e · Cited by 34 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 2
- Spielberger CD Gorsuch RL Lushene RE State Trait Anxiety Inventory Manual 1970 Consulting Psychologists Press, Inc. Palo Alto, CA
- Tomiyama AJ O’Donovan A Lin J Puterman E Lazaro A Chan J Does cellular aging relate to profiles of allostatic load? An examination of HPA axis regulation during reactivity and rest and telomere length in postmenopausal women Physiol. Behav 2011 in press
Cited by
Sorted by citations
Mindfulness meditation and the immune system: a systematic review of randomized controlled trials
Black, D. S., & Slavich, G. M. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12998 · Cited by 599 · see citing works
Mindfulness‐based interventions for obesity‐related eating behaviours: a literature review
O'Reilly, G. A., Cook, L., Spruijt‐Metz, D., & Black, D. S. (2014) · Obesity Reviews · doi:10.1111/obr.12156 · Cited by 547 · see citing works
Ornish, D., Lin, J., Chan, J. M., Epel, E., Kemp, C., Weidner, G., Marlin, R., Frenda, S. J., Magbanua, M. J. M., Daubenmier, J., et al. (2013) · The Lancet Oncology · doi:10.1016/s1470-2045(13)70366-8 · Cited by 390 · see citing works
Self-citationTelomeres and early-life stress: an overview
Price, L. H., Kao, H.-T., Burgers, D. E., Carpenter, L. L., & Tyrka, A. R. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.025 · Cited by 339 · see citing works
Lindqvist, D., Epel, E. S., Mellon, S. H., Penninx, B. W., Révész, D., Verhoeven, J. E., Reus, V. I., Lin, J., Mahan, L., Hough, C. M., et al. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.05.007 · Cited by 285 · see citing works
Self-citationMoffitt, T. E., & Tank, T. K.-G. 2. T. (2013) · Development and Psychopathology · doi:10.1017/s0954579413000801 · Cited by 239 · see citing works
Trait mindfulness and health behaviours: a meta-analysis
Sala, M., Rochefort, C., Lui, P. P., & Baldwin, A. S. (2020) · Health Psychology Review · doi:10.1080/17437199.2019.1650290 · Cited by 199 · see citing works
deVibe, M., Bjørndal, A., Fattah, S., Dyrdal, G. M., Halland, E., & Tanner-Smith, E. E. (2017) · Campbell Systematic Reviews: Better Evidence for a Better World · doi:10.4073/csr.2017.11 · Cited by 198 · see citing works
Carlson, L. E., Beattie, T. L., Giese‐Davis, J., Faris, P., Tamagawa, R., Fick, L. J., Degelman, E. S., & Speca, M. (2015) · Cancer · doi:10.1002/cncr.29063 · Cited by 194 · see citing works
The fetal programming of telomere biology hypothesis: an update
Entringer, S., de Punder, K., Buß, C., & Wadhwa, P. D. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0151 · Cited by 189 · see citing works
Mediterranean Diet, Telomere Maintenance and Health Status among Elderly
Boccardi, V., Esposito, A., Rizzo, M. R., Marfella, R., Barbieri, M., & Paolisso, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062781 · Cited by 189 · see citing works
Shivappa, N., Wirth, M. D., Hurley, T. G., & Hébert, J. R. (2016) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600630 · Cited by 178 · see citing works
A meta-analytic review of the effects of mindfulness meditation on telomerase activity
Schutte, N. S., & Malouff, J. M. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.12.017 · Cited by 171 · see citing works
Lengacher, C. A., Reich, R. R., Kip, K. E., Barta, M., Ramesar, S., Paterson, C. L., Moscoso, M. S., Carranza, I., Budhrani, P. H., Kim, S. J., et al. (2014) · Biological Research For Nursing · doi:10.1177/1099800413519495 · Cited by 169 · see citing works
Sanada, K., Montero-Marin, J., Alda Díez, M., Salas-Valero, M., Pérez-Yus, M. C., Morillo, H., Demarzo, M. M. P., García-Toro, M., & García-Campayo, J. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00471 · Cited by 161 · see citing works
Ruffault, A., Czernichow, S., Hagger, M. S., Ferrand, M., Erichot, N., Carette, C., Boujut, E., & Flahault, C. (2017) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2016.09.002 · Cited by 173 · see citing works
Shalev, I., Moffitt, T. E., Braithwaite, A. W., Danese, A., Fleming, N. I., Goldman-Mellor, S., Harrington, H. L., Houts, R. M., Israel, S., Poulton, R., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.183 · Cited by 155 · see citing works
Early life stress and telomere length: Investigating the connection and possible mechanisms
Shalev, I. (2012) · BioEssays · doi:10.1002/bies.201200084 · Cited by 147 · see citing works
Duchemin, A.-M., Steinberg, B. A., Marks, D. R., Vanover, K., & Klatt, M. (2015) · Journal of Occupational & Environmental Medicine · doi:10.1097/jom.0000000000000371 · Cited by 146 · see citing works
The Telomere/Telomerase System in Chronic Inflammatory Diseases. Cause or Effect?
Kordinas, V., Ioannidis, A., & Chatzipanagiotou, S. (2016) · Genes · doi:10.3390/genes7090060 · Cited by 139 · see citing works
Gavia-García, G., Rosado-Pérez, J., Arista-Ugalde, T. L., Aguíñiga-Sánchez, I., Santiago‐Osorio, E., & Mendoza-Núñez, V. M. (2021) · Biology · doi:10.3390/biology10040253 · Cited by 141 · see citing works
García-Calzón, S., Zalba, G., Ruiz‐Canela, M., Shivappa, N., Hébert, J. R., Martínez, J. A., Fitó, M., Gómez‐Gracia, E., Martínez‐González, M. Á., & Martí, A. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.116863 · Cited by 135 · see citing works
Entringer, S., Buß, C., & Wadhwa, P. D. (2012) · Science Signaling · doi:10.1126/scisignal.2003580 · Cited by 116 · see citing works
Loving-kindness meditation practice associated with longer telomeres in women
Hoge, E. A., Chen, M. M., Orr, E., Metcalf, C. A., Fischer, L. E., Pollack, M. H., DeVivo, I., & Simon, N. M. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2013.04.005 · Cited by 116 · see citing works
Telomeres, Telomerase and Ageing
Saretzki, G. C. (2018) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-2835-0_9 · Cited by 114 · see citing works
Latifovic, L., Peacock, S. D., Massey, T. E., & King, W. D. (2015) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-1364 · Cited by 109 · see citing works
Lawlor, E. R., Islam, N., Bates, S., Griffin, S. J., Hill, A. J., Hughes, C. A., Sharp, S. J., & Ahern, A. L. (2020) · Obesity Reviews · doi:10.1111/obr.13013 · Cited by 103 · see citing works
Innes, K. E., Selfe, T. K., Brundage, K. M., Montgomery, C., Wen, S., Kandati, S., Bowles, H., Khalsa, D. S., & Huysmans, Z. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180164 · Cited by 107 · see citing works
How “reversible” is telomeric aging?
Epel, E. (2012) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-12-0370 · Cited by 103 · see citing works
Grider, H. S., Douglas, S. M., & Raynor, H. A. (2020) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2020.10.019 · Cited by 100 · see citing works
Larouche, E., Hudon, C., & Goulet, S. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.058 · Cited by 93 · see citing works
Stress and immunosenescence: The role of telomerase
de Punder, K., Heim, C. C., Wadhwa, P. D., & Entringer, S. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.10.019 · Cited by 90 · see citing works
Järvelä-Reijonen, E., Karhunen, L., Sairanen, E., Muotka, J., Lindroos, S., Laitinen, J., Puttonen, S., Peuhkuri, K., Hallikainen, M., Pihlajamäki, J., et al. (2018) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-018-0654-8 · Cited by 85 · see citing works
Gazzaniga, F. S., & Blackburn, E. H. (2014) · Blood · doi:10.1182/blood-2014-06-582254 · Cited by 83 · see citing works
Self-citationA new pleiotropic effect of statins in elderly: modulation of telomerase activity
Boccardi, V., Barbieri, M., Rizzo, M. R., Marfella, R., Esposito, A., Marano, L., & Paolisso, G. (2013) · The FASEB Journal · doi:10.1096/fj.13-232066 · Cited by 77 · see citing works
Pain is associated with short leukocyte telomere length in women with fibromyalgia
Hassett, A. L., Epel, E., Clauw, D. J., Harris, R. E., Harte, S. E., Kairys, A., Buyske, S., & Williams, D. A. (2012) · The Journal of Pain · doi:10.1016/j.jpain.2012.07.003 · Cited by 70 · see citing works
Self-citationMeditation, stress processes, and telomere biology
Conklin, Q. A., Crosswell, A. D., Saron, C. D., & Epel, E. S. (2019) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2018.11.009 · Cited by 69 · see citing works
Self-citationTelomerase activation: A potential key modulator for human healthspan and longevity
Boccardi, V., & Paolisso, G. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2013.12.006 · Cited by 69 · see citing works
Conklin, Q. A., King, B. G., Zanesco, A. P., Lin, J., Hamidi, A. B., Pokorny, J. J., Álvarez-López, M. J., Cosín-Tomás, M., Huang, C., Kaliman, P., et al. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.03.003 · Cited by 66 · see citing works
Self-citationDunn, T. J., & Dimolareva, M. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102124 · Cited by 69 · see citing works
Deng, W., Cheung, D. S. T., Tsao, S. W., Wang, X. M., & Tiwari, A. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.11.017 · Cited by 66 · see citing works
Chacko, S. A., Yeh, G. Y., Davis, R. B., & Wee, C. C. (2016) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2016.07.001 · Cited by 60 · see citing works
Cohen, M. M., Elliott, F., Oates, L., Schembri, A. J., & Mantri, N. L. (2017) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2016.0268 · Cited by 59 · see citing works
Song, Y., You, N. Y., Song, Y., Kang, M., Hou, L., Wallace, R. B., Eaton, C. B., Tinker, L. F., & Liu, S. (2013) · Journal of Nutrition · doi:10.3945/jn.113.175422 · Cited by 57 · see citing works
Phillips, A. C., Robertson, T., Carroll, D., Der, G., Shiels, P. G., McGlynn, L., & Benzeval, M. (2013) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318289e6b5 · Cited by 55 · see citing works
Mindful eating and its relationship with body mass index, binge eating,anxiety and negative affect
Pintado-Cucarella, S., & Rodríguez-Salgado, P. (2017) · Journal of Behavior, Health & Social Issues · doi:10.1016/j.jbhsi.2016.11.003 · Cited by 55 · see citing works
Developmental programming of aging trajectory
Vaiserman, A. M., Koliada, A. K., & Lushchak, O. V. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.07.007 · Cited by 57 · see citing works
Mindfulness‐Based Stress Reduction in Women with Overweight or Obesity: A Randomized Clinical Trial
Raja‐Khan, N., Agito, K., Shah, J., Stetter, C. M., Gustafson, T. S., Socolow, H., Kunselman, A. R., Reibel, D. K., & Legro, R. S. (2017) · Obesity · doi:10.1002/oby.21910 · Cited by 53 · see citing works
The Impact of the Environment on the Quality of Life and the Mediating Effects of Sleep and Stress
Chang, K., Wong, F. K. Y., Chan, K. L., Wong, F. Y., Ho, H. C., Wong, M. S., Ho, J. Y. S., Yuen, J. W. M., Siu, J. Y., & Yang, L. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17228529 · Cited by 52 · see citing works
Wang, X., Sundquist, K., Hedelius, A., Palmér, K., Memon, A. A., & Sundquist, J. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1308-0 · Cited by 53 · see citing works
Litzelman, K., Witt, W. P., Gangnon, R. E., Nieto, F. J., Engelman, C. D., Seltzer, M. M., & Skinner, H. G. (2014) · American Journal of Epidemiology · doi:10.1093/aje/kwu066 · Cited by 51 · see citing works
Telomeres, Early-Life Stress and Mental Illness
Ridout, S. J., Ridout, K. K., Kao, H., Carpenter, L. L., Philip, N. S., Tyrka, A. R., & Price, L. H. (2015) · Advances in psychosomatic medicine · doi:10.1159/000369088 · Cited by 47 · see citing works
The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications
Nan, W. Q., Ling, Z., & Bing, C. (2015) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2015.1016500 · Cited by 46 · see citing works
The Telomeric Complex and Metabolic Disease
Kirchner, H., Shaheen, F., Kalscheuer, H., Schmid, S. M., Oster, H., & Lehnert, H. (2017) · Genes · doi:10.3390/genes8070176 · Cited by 46 · see citing works
Mantzios, M., & Egan, H. H. (2018) · Health Psychology Report · doi:10.5114/hpr.2018.73052 · Cited by 46 · see citing works
Cellular aging in depression: Permanent imprint or reversible process?
Verhoeven, J. E., Révész, D., Wolkowitz, O. M., & Penninx, B. W. J. H. (2014) · BioEssays · doi:10.1002/bies.201400068 · Cited by 44 · see citing works
Liu, S., Nong, W., Ji, L., Zhuge, X., Wei, H., Luo, M., Zhou, L., Chen, S., Zhang, S., Lei, X., et al. (2023) · Experimental Gerontology · doi:10.1016/j.exger.2023.112132 · Cited by 43 · see citing works
Zhou, X. H., Zhang, X., Xie, Y., Tanaka, K., Wang, B., & Zhang, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072641 · Cited by 41 · see citing works
Galla, B. M., O'Reilly, G. A., Kitil, M. J., Smalley, S. L., & Black, D. S. (2015) · American Journal of Health Promotion · doi:10.4278/ajhp.131107-quan-567 · Cited by 39 · see citing works
Miller, C. K. (2017) · Diabetes Spectrum · doi:10.2337/ds16-0039 · Cited by 39 · see citing works
Smith, R. S., Alkozei, A., Killgore, W. D. S., & Lane, R. D. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.09.011 · Cited by 38 · see citing works
Mason, A. E., Hecht, F. M., Daubenmier, J. J., Sbarra, D. A., Lin, J., Moran, P. J., Schleicher, S., Acree, M. C., Prather, A. A., & Epel, E. S. (2018) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000616 · Cited by 38 · see citing works
Self-citationThe role of dietary strategies in the modulation of hallmarks of aging
de França, N. A. G., Rolland, Y., Guyonnet, S., & Barreto, P. D. S. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101908 · Cited by 38 · see citing works
Strazhesko, I. D., Ткачева, О. Н., Akasheva, D. U., Dudinskaya, Е. N., Владимировна, П. Е., Pykhtina, V. S., Сергеевна, К. А., Кокшагина, Н. В., Шарашкина, Н. В., Викторович, А. М., et al. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00347 · Cited by 36 · see citing works
Seib, C. A., Whiteside, E., Lee, K. A., Humphreys, J. C., Dao‐Tran, T., Chopin, L. K., & Anderson, D. J. (2014) · Women s Health Issues · doi:10.1016/j.whi.2013.11.004 · Cited by 35 · see citing works
Major Depressive Disorder and Measures of Cellular Aging: An Integrative Review
Kinser, P. A., & Lyon, D. (2013) · Nursing Research and Practice · doi:10.1155/2013/469070 · Cited by 34 · see citing works
CHRONICITY OF DEPRESSION AND MOLECULAR MARKERS IN A LARGE SAMPLE OF HAN CHINESE WOMEN
Edwards, A. C., Aggen, S. H., Cai, N., Bigdeli, T. B., Peterson, R. E., Docherty, A. R., Webb, B. T., Bacanu, S., Flint, J., & Kendler, K. S. (2016) · Depression and Anxiety · doi:10.1002/da.22517 · Cited by 31 · see citing works
Zhu, H., Bhagatwala, J., Pollock, N. K., Parikh, S., Gutin, B., Stallmann-Jorgensen, I. S., Thomas, J., Harshfield, G. A., & Dong, Y. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.51 · Cited by 30 · see citing works
Examination of the reliability and validity of the Mindful Eating Questionnaire in pregnant women
Apolzan, J. W., Myers, C. A., Cowley, A. D., Brady, H., Hsia, D. S., Stewart, T. M., Redman, L. M., & Martin, C. K. (2016) · Appetite · doi:10.1016/j.appet.2016.02.025 · Cited by 29 · see citing works
Pawełczyk, T., Grancow-Grabka, M., Trafalska, E., Szemraj, J., Żurner, N., & Pawełczyk, A. M. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.12.008 · Cited by 29 · see citing works
Sosa‐Cordobés, E., Ramos‐Pichardo, J. D., Sánchez‐Ramos, J. L., Padilla, F. M. G., Martínez, E. F., & Garrido‐Fernández, A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20010446 · Cited by 30 · see citing works
Telomeres and telomere dynamics: relevance to cancers of the GI tract
Basu, N., Skinner, H. G., Litzelman, K., Vanderboom, R. J., Baichoo, E., & Boardman, L. A. (2013) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/17474124.2013.848790 · Cited by 28 · see citing works
Mindfulness, mindful eating e comer intuitivo na abordagem da obesidade e transtornos alimentares
Barbosa, M. R., Penaforte, F. R. D. O., & Silva, A. F. D. S. (2020) · SMAD Revista Eletrônica Saúde Mental Álcool e Drogas (Edição em Português) · doi:10.11606/issn.1806-6976.smad.2020.165262 · Cited by 31 · see citing works
Månsson, K. N. T., Lindqvist, D., Yang, L. L., Svanborg, C., Isung, J., Nilsonne, G., Bergman-Nordgren, L., El Alaoui, S., Hedman-Lagerlöf, E., Kraepelien, M., et al. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0668-2 · Cited by 25 · see citing works
Telomeres and endocrine dysfunction of the adrenal and GH / IGF ‐1 axes
Aulinas, A., Barahona, M. J., Barahona, M. J., Mato, E., Bell, O. L., Surrallés, J., & Webb, S. M. (2013) · Clinical Endocrinology · doi:10.1111/cen.12310 · Cited by 26 · see citing works
Women’s Health and Mindfulness (WHAM): A Randomized Intervention Among Older Lesbian/Bisexual Women
Ingraham, N., Harbatkin, D., Lorvick, J., Plumb, M., & Minnis, A. M. (2016) · Health Promotion Practice · doi:10.1177/1524839916670874 · Cited by 24 · see citing works
Telomere length analysis in Cushing's syndrome
Aulinas, A., Ramírez, M., Barahona, M. J., Valassi, E., Resmini, E., Mato, E., Vives, A. S., Crespo, I., Bell, O. L., Surrallés, J., et al. (2014) · European Journal of Endocrinology · doi:10.1530/eje-14-0098 · Cited by 24 · see citing works
Soltero, E. G., Larkey, L., Kim, S. W., Chavez, J. R., & Lee, R. E. (2022) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2022.101554 · Cited by 24 · see citing works
Functional genomics in the study of mind-body therapies.
Niles, H. F., Mehta, D. H., Corrigan, A. A., Bhasin, M., & Denninger, J. W. (2014) · PubMed Central · Cited by 23 · see citing works
Implication of asana, pranayama and meditation on telomere stability
Abraham, J., & Rathore, M. (2018) · International Journal of Yoga · doi:10.4103/ijoy.ijoy_51_17 · Cited by 23 · see citing works
Weight‐neutral interventions in young people with high body mass index: A systematic review
Hoare, J. K., Lister, N. B., Garnett, S. P., Baur, L. A., & Jebeile, H. (2022) · Nutrition & Dietetics · doi:10.1111/1747-0080.12729 · Cited by 20 · see citing works
Mutschler, J., Abbruzzese, E., Wiedemann, K., von der Goltz, C., Dinter, C., Mobascher, A., Thiele, H., Diaz-Lacava, A. N., Dahmen, N., Gallinat, J., et al. (2013) · Annals of Nutrition and Metabolism · doi:10.1159/000346799 · Cited by 20 · see citing works
Black, D. S., O’Reilly, G. A., Olmstead, R., Breen, E. C., & Irwin, M. R. (2014) · Contemporary Clinical Trials · doi:10.1016/j.cct.2014.06.013 · Cited by 20 · see citing works
Health, Illness, and the Psychological Factors Affecting Them
Rokach, A. (2019) · The Journal of Psychology · doi:10.1080/00223980.2018.1548202 · Cited by 18 · see citing works
Mindfulness-based lifestyle programs for the self-management of Parkinson’s disease in Australia
Vandenberg, B. E., Advocat, J., Hassed, C., Hester, J., Enticott, J., & Russell, G. (2019) · Health Promotion International · doi:10.1093/heapro/day021 · Cited by 17 · see citing works
Meditation for the primary and secondary prevention of cardiovascular disease
Rees, K., Takeda, A., Court, R. A., Kudrna, L., Hartley, L., & Ernst, E. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013358.pub2 · Cited by 18 · see citing works
Tiwari, A., Chan, C., Ho, R., Tsao, G. S., Deng, W., Hong, A. W. L., Fong, D., Fung, H. Y. K. Y., Pang, E. P. S., Cheung, D. S. T., et al. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-300 · Cited by 17 · see citing works
de Punder, K., Heim, C. C., Przesdzing, I., Wadhwa, P. D., & Entringer, S. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0441 · Cited by 17 · see citing works
Telomere length and telomerase activity in the context of menopause
Pines, A. (2013) · Climacteric · doi:10.3109/13697137.2013.812603 · Cited by 16 · see citing works
Preliminary evidence that age and sex affect exercise-induced hTERT expression
Cluckey, T. G., Nieto, N. C., Rodoni, B. M., & Traustadóttir, T. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.06.003 · Cited by 16 · see citing works
Smearman, E., Yu, T., & Brody, G. H. (2016) · Brain and Behavior · doi:10.1002/brb3.423 · Cited by 16 · see citing works
Integrated health and post modern medicine
Wales, H. T. P. O. (2012) · Journal of the Royal Society of Medicine · doi:10.1258/jrsm.2012.12k095 · Cited by 15 · see citing works
Bossert, L., Arzberger, K., Dorok, F., Kern, J., Stickler, C., Wunderlich, M., & Tran, U. S. (2023) · Mindfulness · doi:10.1007/s12671-023-02075-x · Cited by 15 · see citing works
Gentile, C., Starnino, L., Dupuis, G., & D’Antono, B. (2021) · Clinical Gerontologist · doi:10.1080/07317115.2021.1887421 · Cited by 14 · see citing works
Neural Basis of Mindfulness Interventions that Moderate the Impact of Stress on the Brain
Paulus, M. P. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.239 · Cited by 14 · see citing works
Telomeres and stress: Promising avenues for research in psycho-oncology
Law, E., Girgis, A., Sylvie, L., Levesque, J. V., & Pickett, H. A. (2016) · Asia-Pacific Journal of Oncology Nursing · doi:10.4103/2347-5625.182931 · Cited by 14 · see citing works
Sun, S., Sheridan, M. A., Tyrka, A. R., Donofry, S. D., Erickson, K. I., & Loucks, E. B. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104526 · Cited by 15 · see citing works
Larkey, L., Vega‐López, S., Keller, C. S., McClain, D. B., Ainsworth, B. E., Ohri‐Vachaspati, P., Smith, L., & Jeong, M. (2014) · Health Psychology Open · doi:10.1177/2055102914565495 · Cited by 13 · see citing works
All you can eat Buffets, obesity, mindfulness, and mindful eating: An exploratory investigation
Ali, Z., Wong, K., Egan, H. H., Cook, A., & Mantzios, M. (2017) · Journal of Psychology and Psychiatry · doi:10.15761/jpp.1000101 · Cited by 12 · see citing works
The Influence of Meditative Interventions on Immune Functioning: A Meta-Analysis
Oyler, D. L., Hulett, J. M., Pratscher, S. D., Price‐Blackshear, M. A., Murphy, E. A., & Bettencourt, B. A. (2023) · Mindfulness · doi:10.1007/s12671-023-02157-w · Cited by 11 · see citing works
- Authors
- Daubenmier, J., Lin, J., Blackburn, E., Hecht, F. M., Kristeller, J., Maninger, N., Kuwata, M., Bacchetti, P., Havel, P. J., & Epel, E.
- Affiliations
- University of California, San Francisco (US)
- Indiana State University (US)
- University of California, Davis (US)
- Corresponding author
- Daubenmier, Jennifer
- Epel, Elissa
- ORCID
- Venue
- Psychoneuroendocrinology
- Publisher
- Elsevier BV
- Published
- 2012-07
- Volume
- 37
- Issue
- 7
- Pages
- 917-928
- ISSN
- 0306-4530 (ISSN-L)
- PMC
- PMC3384690
- OpenAlex
- W2038793808
- Cited by
- 157
- References
- 58
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 5 · 2023: 8 · 2022: 9 · 2021: 9 · 2020: 9 · 2019: 8 · 2018: 14 · 2017: 13 · 2016: 16 · 2015: 13 · 2014: 19 · 2013: 17 · 2012: 8
- FWCI
- 15.19
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychoneuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- University of California, San Francisco
- National Center for Research Resources (UL1RR024131)
- National Center for Complementary and Integrative Health (K01AT004199, P01AT005013)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Physiology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Keywords
- telomerase activity, mindfulness-based interventions, stress eating, psychological distress, dietary habits, dietary restraint, dietary fat intake, cortisol, insulin resistance, metabolic dysfunction, cellular aging, overweight and obesity, women, peripheral blood mononuclear cells
- MeSH terms
- Adult, Feeding and Eating Disorders, Eating, Feeding Behavior, Female, Humans, Metabolism, Obesity, Pilot Projects, Stress, Psychological, Waiting Lists, Telomerase, Risk Reduction Behavior, Overweight, Compassionate Use Trials
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
