Cited by 91Mindfulness and Compassion InterventionsSchizophrenia research and treatmentPsychotherapy Techniques and Applications

Is it the symptom or the relation to it? Investigating potential mediators of change in Acceptance and Commitment Therapy for psychosis

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Gaudiano, Brandon A., Herbert, James D., Hayes, Steven C.·2010·Behavior Therapy

Abstract

Cognitive and behavioral interventions have been shown to be efficacious when used as an adjunct to pharmacotherapy for psychotic disorders. However, little previous research has investigated potential mediators of change in psychological treatments for psychosis. Acceptance and mindfulness-based therapies do not focus on directly reducing the psychotic symptoms themselves, but instead attempt to alter the patient's relationship to symptoms to decrease their negative impact. The current study examined this issue with data from a previously published randomized trial comparing brief treatment with Acceptance and Commitment Therapy (ACT) versus treatment as usual for hospitalized patients with psychotic symptoms (Gaudiano & Herbert, 2006a). Results showed that the believability of hallucinations at posttreatment statistically mediated the effect of treatment condition on hallucination-related distress. Hallucination frequency did not mediate outcome. The current study is a first step toward understanding the potential mechanisms of action in psychological treatments for psychosis.

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Authors
Gaudiano, B. A., Herbert, J. D., & Hayes, S. C.
Affiliations
  • Brown University (US)
  • Drexel University (US)
  • University of Nevada, Reno (US)
Corresponding author
Gaudiano, Brandon A.
Venue
Behavior Therapy
Publisher
Elsevier BV
Published
2010-12
Volume
41
Issue
4
Pages
543-554
ISSN
0005-7894 (ISSN-L)
OpenAlex
W2045103741
Cited by
91
References
59
Citations by year
2025: 3 · 2024: 4 · 2023: 6 · 2022: 9 · 2021: 5 · 2020: 7 · 2019: 4 · 2018: 4 · 2017: 4 · 2016: 6 · 2015: 9 · 2014: 5 · 2013: 12 · 2012: 6
FWCI
8.81
Type
journal article
Language
en
Open access
Locations
  • Behavior Therapy (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (K23MH076937)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords
acceptance and commitment therapy, psychosis, hallucinations, mediators of change, mechanism of action, hospitalized patients, brief psychological intervention, usual care
MeSH terms
Adult, Behavior Therapy, Female, Hallucinations, Humans, Male, Psychotic Disorders, Randomized Controlled Trials as Topic

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