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Cited by 334

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The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

Arranz, Amaia M, De Strooper, Bart·2019·The Lancet Neurology
DOI 10.1016/s1474-4422(18)30490-3
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  • The role of astrocytes in the pathogenesis of FTD and other neurodegenerative diseases is increasingly being recognized.

    “Although most of the research in FTD has been focused on neuronal dysfunction and neuronal cell death, the role of astrocytes in the pathogenesis of FTD and other neurodegenerative diseases is increasingly being recognized [39, 81–83].”

    From A role for astrocytic miR-129-5p in frontotemporal dementia (2025) · cites this paper as [82]

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Research works printed but not linked: 56

  1. Almeida, 2018, Updated meta-analysis of BIN1, CR1, MS4A6A, CLU, and ABCA7 variants in Alzheimer's disease, J Mol Neurosci, 64, 471, 10.1007/s12031-018-1045-y · DOI
  2. Ikezu, 2018, Tau phosphorylation is impacted by rare AKAP9 mutations associated with Alzheimer disease in African Americans, J Neuroimmune Pharmacol, 13, 254, 10.1007/s11481-018-9781-x · DOI
  3. Shi, 2018, Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight, Nat Rev Immunol, 18, 759, 10.1038/s41577-018-0051-1 · DOI · Paper page
  4. Liu, 2016, Alzheimer's disease CD33 rs3865444 variant does not contribute to cognitive performance, Proc Natl Acad Sci USA, 113, E1589
  5. Chapuis, 2017, Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism, Acta Neuropathol, 133, 955, 10.1007/s00401-016-1652-z · DOI · Paper page
  6. Wang, 2017, Effects of HLA-DRB1/DQB1 genetic variants on neuroimaging in healthy, mild cognitive impairment, and Alzheimer's disease cohorts, Mol Neurobiol, 54, 3181, 10.1007/s12035-016-9890-6 · DOI
  7. Wes, 2016, Targeting microglia for the treatment of Alzheimer's disease, Glia, 64, 1710, 10.1002/glia.22988 · DOI · Paper page
  8. Jing, 2016, INPP5D rs35349669 polymorphism with late-onset Alzheimer's disease: a replication study and meta-analysis, Oncotarget, 7, 69225, 10.18632/oncotarget.12648 · DOI · Paper page
  9. Tang, 2016, MEF2C rs190982 polymorphism with late-onset Alzheimer's disease in Han Chinese: a replication study and meta-analyses, Oncotarget, 7, 39136, 10.18632/oncotarget.9819 · DOI · Paper page
  10. Wang, 2016, Meta-analysis of the Association between Alzheimer Disease and Variants in GAB2, PICALM, and SORL1, Mol Neurobiol, 53, 6501, 10.1007/s12035-015-9546-y · DOI
  11. Li, 2016, Common variant in PTK2B is associated with late-onset Alzheimer's disease: a replication study and meta-analyses, Neurosci Lett, 621, 83, 10.1016/j.neulet.2016.04.020 · DOI
  12. Zhang, 2016, Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse, Neuron, 89, 37, 10.1016/j.neuron.2015.11.013 · DOI · Paper page
  13. Verheijen, 2018, Understanding Alzheimer disease at the interface between genetics and transcriptomics, Trends Genet, 34, 434, 10.1016/j.tig.2018.02.007 · DOI · Paper page
  14. Efthymiou, 2017, Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk, Mol Neurodegener, 12, 43, 10.1186/s13024-017-0184-x · DOI · Paper page
  15. Salter, 2017, Microglia emerge as central players in brain disease, Nat Med, 23, 1018, 10.1038/nm.4397 · DOI · Paper page
  16. Yun, 2018, Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease, Nat Med, 24, 931, 10.1038/s41591-018-0051-5 · DOI · Paper page
  17. Ouali Alami, 2018, NF–κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS, EMBO J, 37, e98697, 10.15252/embj.201798697 · DOI
  18. Rasmussen, 2018, The glymphatic pathway in neurological disorders, Lancet Neurol, 17, 1016, 10.1016/S1474-4422(18)30318-1 · DOI · Paper page
  19. Verkhratsky, 2018, Physiology of astroglia, Physiol Rev, 98, 239, 10.1152/physrev.00042.2016 · DOI · Paper page
  20. Ferrer, 2017, Diversity of astroglial responses across human neurodegenerative disorders and brain aging, Brain Pathol, 27, 645, 10.1111/bpa.12538 · DOI
  21. Oberheim, 2009, Uniquely hominid features of adult human astrocytes, J Neurosci, 29, 3276, 10.1523/JNEUROSCI.4707-08.2009 · DOI · Paper page
  22. Vasile, 2017, Human astrocytes: structure and functions in the healthy brain, Brain Struct Funct, 222, 2017, 10.1007/s00429-017-1383-5 · DOI · Paper page
  23. Han, 2013, Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice, Cell Stem Cell, 12, 342, 10.1016/j.stem.2012.12.015 · DOI · Paper page
  24. Pekny, 2016, Astrocytes: a central element in neurological diseases, Acta Neuropathologica, 131, 323, 10.1007/s00401-015-1513-1 · DOI
  25. Verkhratsky, 2017, Stratification of astrocytes in healthy and diseased brain, Brain Pathol, 27, 629, 10.1111/bpa.12537 · DOI · Paper page
  26. Hsu, 2018, Astrocytic degeneration in chronic traumatic encephalopathy, Acta Neuropathol, 136, 955, 10.1007/s00401-018-1902-3 · DOI
  27. Verkhratsky, 2016, Astroglia dynamics in ageing and Alzheimer's disease, Curr Opin Pharmacol, 26, 74, 10.1016/j.coph.2015.09.011 · DOI
  28. Rodríguez-Arellano, 2016, Astrocytes in physiological aging and Alzheimer's disease, Neuroscience, 323, 170, 10.1016/j.neuroscience.2015.01.007 · DOI · Paper page
  29. Orre, 2014, Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction, Neurobiol Aging, 35, 2746, 10.1016/j.neurobiolaging.2014.06.004 · DOI · Paper page
  30. Jones, 2017, Aberrant iPSC-derived human astrocytes in Alzheimer's disease, Cell Death Dis, 8, e2696, 10.1038/cddis.2017.89 · DOI · Paper page
  31. Zorec, 2017, Astrocytic face of Alzheimer's disease, Behav Brain Res, 322, 250, 10.1016/j.bbr.2016.05.021 · DOI · Paper page
  32. Mathys, 2017, Temporal tracking of microglia activation in neurodegeneration at single-cell resolution, Cell Rep, 21, 366, 10.1016/j.celrep.2017.09.039 · DOI · Paper page
  33. Liddelow, 2017, Reactive atrocytes: production, function, and therapeutic potential, Immunity, 46, 957, 10.1016/j.immuni.2017.06.006 · DOI · Paper page
  34. Sekar, 2016, Schizophrenia risk from complex variation of complement component 4, Nature, 530, 177, 10.1038/nature16549 · DOI · Paper page
  35. Frost, 2017, The role of astrocytes in amyloid production and Alzheimer's disease, Open Biol, 7, 170228, 10.1098/rsob.170228 · DOI
  36. Zhao, 2017, APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes, Hum Mol Genet, 26, 2690, 10.1093/hmg/ddx155 · DOI · Paper page
  37. Simonovitch, 2016, Impaired autophagy in APOE4 astrocytes, J Alzheimers Dis, 51, 915, 10.3233/JAD-151101 · DOI · Paper page
  38. Huynh, 2017, Age-dependent effects of apoE reduction using antisense oligonucleotides in a model of β-amyloidosis, Neuron, 96, 1013, 10.1016/j.neuron.2017.11.014 · DOI · Paper page
  39. Liu, 2017, ApoE4 accelerates early seeding of amyloid pathology, Neuron, 96, 1024, 10.1016/j.neuron.2017.11.013 · DOI · Paper page
  40. Sweeney, 2018, Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders, Nat Rev Neurol, 14, 133, 10.1038/nrneurol.2017.188 · DOI · Paper page
  41. Lian, 2016, Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease, J Neurochem, 136, 475, 10.1111/jnc.13424 · DOI · Paper page
  42. Goetzl, 2018, High complement levels in astrocyte-derived exosomes of Alzheimer disease, Ann Neurol, 83, 544, 10.1002/ana.25172 · DOI
  43. Diniz, 2017, Astrocyte transforming growth factor beta 1 protects synapses against Aβ oligomers in Alzheimer's disease model, J Neurosci, 37, 6797, 10.1523/JNEUROSCI.3351-16.2017 · DOI · Paper page
  44. Gomez-Arboledas, 2018, Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease, Glia, 66, 637, 10.1002/glia.23270 · DOI · Paper page
  45. Ekert, 2018, TNF alpha inhibitors in Alzheimer's disease: a systematic review, Int J Geriatr Psychiatry, 33, 688, 10.1002/gps.4871 · DOI
  46. Decourt, 2017, Targeting tumor necrosis factor alpha for Alzheimer's disease, Curr Alzheimer Res, 14, 412, 10.2174/1567205013666160930110551 · DOI
  47. Chang, 2017, Blood–brain barrier penetrating biologic TNF-α inhibitor for Alzheimer's disease, Mol Pharm, 14, 2340, 10.1021/acs.molpharmaceut.7b00200 · DOI
  48. Goldbach-Mansky, 2009, Blocking interleukin-1 in rheumatic diseases, Ann N Y Acad Sci, 1182, 111
  49. Lansita, 2017, Nonclinical development of ANX005: a humanized anti-C1q antibody for treatment of autoimmune and neurodegenerative diseases, Int J Toxicol, 36, 449, 10.1177/1091581817740873 · DOI
  50. Lian, 2016, Astrocyte-microglia cross talk through complement activation modulates amyloid pathology in mouse models of Alzheimer's disease, J Neurosci, 36, 577, 10.1523/JNEUROSCI.2117-15.2016 · DOI · Paper page
  51. Gonçalves, 2016, Protective effect of a GLP-1 analog on ischemia-reperfusion induced blood–retinal barrier breakdown and inflammation, Investig Ophthalmol Vis Sci, 57, 2584, 10.1167/iovs.15-19006 · DOI
  52. Gullo, 2017, Plant polyphenols and exendin-4 prevent hyperactivity and TNF-α release in LPS-treated in vitro neuron/astrocyte/microglial networks, Front Neurosci, 11, 500, 10.3389/fnins.2017.00500 · DOI
  53. Lee, 2018, Activation of glucagon-like peptide-1 receptor promotes neuroprotection in experimental autoimmune encephalomyelitis by reducing neuroinflammatory responses, Mol Neurobiol, 55, 3007, 10.1007/s12035-017-0550-2 · DOI
  54. Reichenbach, 2018, P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model, J Exp Med, 215, 1649, 10.1084/jem.20171487 · DOI · Paper page
  55. Rodriguez-Vieitez, 2016, Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease, Brain, 139, 922, 10.1093/brain/awv404 · DOI
  56. Alcolea, 2015, Relationship between cortical thickness and cerebrospinal fluid YKL-40 in predementia stages of Alzheimer's disease, Neurobiol Aging, 36, 2018, 10.1016/j.neurobiolaging.2015.03.001 · DOI

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Metadata

Authors
Arranz, A. M., & De Strooper, B.
Venue
The Lancet Neurology
Publisher
Elsevier BV
Published
2019-04
Volume
18
Issue
4
Pages
406-414
ISSN
1474-4422
DOI
10.1016/s1474-4422(18)30490-3
Cited by
334
References
17
Language
en
Licence
Funders
  • KU Leuven
  • Biogen
  • Vlaamse regering
  • Fonds Wetenschappelijk Onderzoek
  • Alzheimer's Association
  • Eisai

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