Cited by 334Sleep and related disordersCircadian rhythm and melatoninSleep and Work-Related Fatigue

The DOI matches its Crossref record; 101 of the 103 references it cites were found in a registry or an index.

The metabolic burden of sleep loss

Schmid, Sebastian M, Hallschmid, Manfred, Schultes, Bernd·2015·The Lancet Diabetes & Endocrinology

Open this paper in CoChat — free account

Abstract

In parallel with the increasing prevalence of obesity and type 2 diabetes, sleep loss has become common in modern societies. An increasing number of epidemiological studies show an association between short sleep duration, sleep disturbances, and circadian desynchronisation of sleep with adverse metabolic traits, in particular obesity and type 2 diabetes. Furthermore, experimental studies point to distinct mechanisms by which insufficient sleep adversely affects metabolic health. Changes in the activity of neuroendocrine systems seem to be major mediators of the detrimental metabolic effects of insufficient sleep, through favouring neurobehavioural outcomes such as increased appetite, enhanced sensitivity to food stimuli, and, ultimately, a surplus in energy intake. The effect of curtailed sleep on physical activity and energy expenditure is less clear, but changes are unlikely to outweigh increases in food intake. Although long-term interventional studies proving a cause and effect association are still scarce, sleep loss seems to be an appealing target for the prevention, and probably treatment, of metabolic disease.

Integrity signals

Registry

Crossref · 10.1016/s2213-8587(14)70012-9

Cites

101 of 101 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

RETRACTED: CPAP for the Metabolic Syndrome in Patients with Obstructive Sleep Apnea
Sharma, S. K., Agrawal, S., Damodaran, D., Sreenivas, V., Kadhiravan, T., Ramakrishnan, L., Jagia, P., & Kumar, A. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1103944 · Cited by 366
Retracted
Harmonizing the Metabolic Syndrome: A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
Alberti, K. G. M. M., Eckel, R. H., Grundy, S. M., Zimmet, P. Z., Cleeman, J. I., Donato, K. A., Fruchart, J.-C., James, W. P. T., Loria, C. M., & Smith, S. C. (2009) · Circulation · doi:10.1161/circulationaha.109.192644 · Cited by 14,860
Central nervous system control of food intake
Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451
Impact of sleep debt on metabolic and endocrine function
Spiegel, K., Leproult, R., & Van Cauter, E. (1999) · The Lancet · doi:10.1016/s0140-6736(99)01376-8 · Cited by 3,668
About Sleep's Role in Memory
Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783
Central nervous system control of food intake and body weight
Morton, G. J., Cummings, D. E., Baskin, D. G., Barsh, G. S., & Schwartz, M. W. (2006) · Nature · doi:10.1038/nature05026 · Cited by 2,503
Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite
Spiegel, K., Tasali, E., Penev, P., & Cauter, E. V. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-141-11-200412070-00008 · Cited by 2,459
Adverse metabolic and cardiovascular consequences of circadian misalignment
Scheer, F. A. J. L., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808180106 · Cited by 2,351
Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies
Cappuccio, F. P., D'Elia, L., Strazzullo, P., & Miller, M. A. (2010) · Sleep · doi:10.1093/sleep/33.5.585 · Cited by 2,224
Meta-Analysis of Short Sleep Duration and Obesity in Children and Adults
Cappuccio, F. P., Taggart, F. M., Kandala, N.-B., Currie, A., Peile, E., Stranges, S., & Miller, M. A. (2008) · Sleep · doi:10.1093/sleep/31.5.619 · Cited by 2,076

Show all 103 references

Sorted by citations

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
Kautzky-Willer, A., Harreiter, J., & Pacini, G. (2016) · Endocrine Reviews · doi:10.1210/er.2015-1137 · Cited by 2,043
Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies
Shan, Z., Ma, H., Xie, M., Yan, P., Guo, Y., Bao, W., Rong, Y., Jackson, C. L., Hu, F. B., & Liu, L. (2015) · Diabetes Care · doi:10.2337/dc14-2073 · Cited by 902
Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms
Jones, S. E., Lane, J. M., Wood, A. R., van Hees, V. T., Tyrrell, J., Beaumont, R. N., Jeffries, A. R., Dashti, H. S., Hillsdon, M., Ruth, K. S., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-08259-7 · Cited by 691
Effects of Psychological, Environmental and Physical Stressors on the Gut Microbiota
Karl, J. P., Hatch‐McChesney, A., Arcidiacono, S. M., Pearce, S., Pantoja-Feliciano, I. G., Doherty, L. A., & Soares, J. W. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02013 · Cited by 563
The impact of sleep amount and sleep quality on glycemic control in type 2 diabetes: a systematic review and meta-analysis
Lee, S. W. H., Ng, K. Y., & Chin, W. K. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.02.001 · Cited by 470
Importance of All Movement Behaviors in a 24 Hour Period for Overall Health
Chaput, J.-P., Carson, V., Gray, C., & Tremblay, M. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph111212575 · Cited by 444
Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci
Jones, S. E., Tyrrell, J., Wood, A. R., Beaumont, R. N., Ruth, K. S., Tuke, M. A., Yaghootkar, H., Hu, Y., Teder-Laving, M., Hayward, C., et al. (2016) · PLOS Genetics · doi:10.1371/journal.pgen.1006125 · Cited by 388
The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany
Loeffler, M., Engel, C., Ahnert, P., Alfermann, D., Arélin, K., Baber, R., Beutner, F., Binder, H., Brähler, E., Burkhardt, R., et al. (2015) · BMC Public Health · doi:10.1186/s12889-015-1983-z · Cited by 360
Sleep health of Australian adults in 2016: results of the 2016 Sleep Health Foundation national survey
Adams, R., Appleton, S., Taylor, A. W., Gill, T. K., Lang, C. J., McEvoy, R. D., & Antic, N. A. (2017) · Sleep Health · doi:10.1016/j.sleh.2016.11.005 · Cited by 289
Effects of caffeine on sleep quality and daytime functioning
O’Callaghan, F., Muurlink, O. T., & Reid, N. (2018) · Risk Management and Healthcare Policy · doi:10.2147/rmhp.s156404 · Cited by 264
Sleep Loss and the Socio-Emotional Brain
Simon, E. B., Vallat, R., Barnes, C. M., & Walker, M. P. (2020) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2020.02.003 · Cited by 261
Lack of sleep as a contributor to obesity in adolescents: impacts on eating and activity behaviors
Chaput, J.-P., & Dutil, C. (2016) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-016-0428-0 · Cited by 243
Comparison of Self-Reported Sleep Duration With Actigraphy: Results From the Hispanic Community Health Study/Study of Latinos Sueño Ancillary Study
Feliciano, E. M. C., Hu, F. B., Redline, S. S., ROSNER, B. A., Alcántara, C., Cai, J., Hall, M. H., Loredo, J. S., Mossavar‐Rahmani, Y., Ramos, A. R., et al. (2016) · American Journal of Epidemiology · doi:10.1093/aje/kwv251 · Cited by 243
Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure
Bonmatí‐Carrión, M., Argüelles-Prieto, R., Martínez-Madrid, M. J., Reiter, R. J., Hardeland, R., Rol, M. A., & Madrid, J. A. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms151223448 · Cited by 254
Influence of Gender in Diabetes Mellitus and Its Complication
Ciarambino, T., Crispino, P., Leto, G., Mastrolorenzo, E., Para, O., & Giordano, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23168850 · Cited by 226
Adverse Cardiovascular Effects of Traffic Noise with a Focus on Nighttime Noise and the New WHO Noise Guidelines
Münzel, T. F., Kröller‐Schön, S., Oelze, M. W., Gori, T., Schmidt, F. P., Steven, S., Hahad, O., Röösli, M., Wunderli, J. M., Daiber, A., et al. (2020) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-081519-062400 · Cited by 222
Association between long sleep duration and increased risk of obesity and type 2 diabetes: A review of possible mechanisms
Tan, X. W., Chapman, C. D., Cedernaes, J., & Benedict, C. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.11.001 · Cited by 202
Objectively measured short sleep duration and later sleep midpoint in pregnancy are associated with a higher risk of gestational diabetes
Facco, F. L., Grobman, W. A., Reid, K. J., Parker, C. B., Hunter, S. M., Silver, R. M., Basner, R. C., Saade, G. R., Pien, G. W., Manchanda, S., et al. (2017) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.05.066 · Cited by 189
Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men
Cedernaes, J., Osler, M. E., Voisin, S., Broman, J.-E., Vogel, H., Dickson, S. L., Zierath, J. R., Schiöth, H. B., & Benedict, C. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-2284 · Cited by 188
Sleep and cardiometabolic risk in children and adolescents
Quist, J. S., Sjödin, A. M., Chaput, J., & Hjorth, M. F. (2015) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.09.001 · Cited by 165
Association between short and long sleep durations and cardiovascular outcomes: a systematic review and meta-analysis
Krittanawong, C., Tunhasiriwet, A., Wang, Z., Zhang, H., Farrell, A. M., Chirapongsathorn, S., Sun, T., Kitai, T., & Argulian, E. (2017) · European Heart Journal Acute Cardiovascular Care · doi:10.1177/2048872617741733 · Cited by 162
Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors
Pearce, S., Coia, H. G., Karl, J. P., Pantoja-Feliciano, I. G., Zachos, N. C., & Racicot, K. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01584 · Cited by 167
Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt
Weljie, A. M., Meerlo, P., Goel, N., Sengupta, A., Kayser, M. S., Abel, T., Birnbaum, M. J., Dinges, D. F., & Sehgal, A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1417432112 · Cited by 158
Subchronic sleep restriction causes tissue-specific insulin resistance
Rao, M. N., Neylan, T. C., Grunfeld, C., Mulligan, K., Schambelan, M., & Schwarz, J.-M. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-3911 · Cited by 156
Sleep extension improves serving accuracy: A study with college varsity tennis players
Schwartz, J., & Simon, R. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.08.035 · Cited by 140
Interactions between sleep, movement and other non‐movement behaviours in the pathogenesis of childhood obesity
Chaput, J., Saunders, T. J., & Carson, V. (2017) · Obesity Reviews · doi:10.1111/obr.12508 · Cited by 139
Prevalence of sleep disturbances in Chinese healthcare professionals: a systematic review and meta-analysis
Qiu, D., Yu, Y., Li, R., Li, Y., & Xiao, S. (2019) · Sleep Medicine · doi:10.1016/j.sleep.2019.01.047 · Cited by 139
Short Sleep Duration Increases Metabolic Impact in Healthy Adults: A Population-Based Cohort Study
Deng, H., Tam, T., Zee, B. C.-Y., Chung, R. Y., Su, X., Jin, L., Chan, T., Chang, L.-Y., Yeoh, E., & Lao, X. Q. (2017) · SLEEP · doi:10.1093/sleep/zsx130 · Cited by 137
Association between sleep deficiency and cardiometabolic disease: implications for health disparities
Rangaraj, V. R., & Knutson, K. L. (2016) · Sleep Medicine · doi:10.1016/j.sleep.2015.02.535 · Cited by 120
A practical approach to the management of nocturia
Oelke, M., Wachter, S. D., Drake, M. J., Giannantoni, A., Kirby, M. G., Orme, S., Rees, J., Kerrebroeck, P. V., & Everaert, K. (2017) · International Journal of Clinical Practice · doi:10.1111/ijcp.13027 · Cited by 116
Objective Sleep Characteristics and Cardiometabolic Health in Young Adolescents
Feliciano, E. M. C., Quante, M., Rifas‐Shiman, S. L., Redline, S. S., Oken, E., & Taveras, E. M. (2018) · PEDIATRICS · doi:10.1542/peds.2017-4085 · Cited by 115
Associations between sleep patterns and lifestyle behaviors in children: an international comparison
for the ISCOLE Research Group, Chaput, J.-P., Katzmarzyk, P. T., LeBlanc, A. G., Tremblay, M. S., Barreira, T. V., Broyles, S. T., Fogelholm, M., Hu, G., Kuriyan, R., et al. (2015) · International Journal of Obesity Supplements · doi:10.1038/ijosup.2015.21 · Cited by 114
Association Between Sleep Timing, Obesity, Diabetes: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Cohort Study
Knutson, K. L., Wu, D., Patel, S. R., Loredo, J. S., Redline, S. S., Cai, J., Gallo, L. C., Mossavar‐Rahmani, Y., Ramos, A. R., Teng, Y., et al. (2017) · SLEEP · doi:10.1093/sleep/zsx014 · Cited by 113
Prevalence and comorbidity of sleep conditions in Australian adults: 2016 Sleep Health Foundation national survey
Appleton, S., Gill, T. K., Lang, C. J., Taylor, A. W., McEvoy, R. D., Stocks, N. P., González‐Chica, D. A., & Adams, R. (2017) · Sleep Health · doi:10.1016/j.sleh.2017.10.006 · Cited by 117
Effects of acute sleep loss on leptin, ghrelin, and adiponectin in adults with healthy weight and obesity: A laboratory study
van Egmond, L. T., Meth, E. M. S., Engström, J., Ilemosoglou, M., Keller, J. A., Vogel, H., & Benedict, C. (2023) · Obesity · doi:10.1002/oby.23616 · Cited by 106
Effects of sleep manipulation on markers of insulin sensitivity: A systematic review and meta-analysis of randomized controlled trials
Sondrup, N., Termannsen, A., Eriksen, J. N., Hjorth, M. F., Færch, K., Klingenberg, L., & Quist, J. S. (2022) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2022.101594 · Cited by 105
Determinants of shortened, disrupted, and mistimed sleep and associated metabolic health consequences in healthy humans
Cedernaes, J., Schiöth, H. B., & Benedict, C. (2015) · Diabetes · doi:10.2337/db14-1475 · Cited by 103
Estimating individual optimal sleep duration and potential sleep debt
Kitamura, S., Katayose, Y., Nakazaki, K., Motomura, Y., Oba, K., Katsunuma, R., Terasawa, Y., Enomoto, M., Moriguchi, Y., Hida, A., et al. (2016) · Scientific Reports · doi:10.1038/srep35812 · Cited by 93
Neurobiological and Hormonal Mechanisms Regulating Women’s Sleep
Dorsey, A., de Lecea, L., & Jennings, K. J. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.625397 · Cited by 100
Sleep and HbA1c in Patients With Type 2 Diabetes: Which Sleep Characteristics Matter Most?
Brouwer, A., van Raalte, D. H., Rutters, F., Elders, P. J. M., Snoek, F. J., Beekman, A. T. F., & Bremmer, M. A. (2019) · Diabetes Care · doi:10.2337/dc19-0550 · Cited by 97
AHA Life's essential 8 and ideal cardiovascular health among young adults
Shetty, N. S., Parcha, V., Patel, N., Yadav, I. S., Basetty, C. R., Li, C., Pandey, A., Kalra, R., Li, P., Arora, G., et al. (2022) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2022.100452 · Cited by 95
Prevalence of Insomnia (Symptoms) in T2D and Association With Metabolic Parameters and Glycemic Control: Meta-Analysis
Koopman, A. D. M., Beulens, J. W. J., Dijkstra, T., Pouwer, F., Bremmer, M. A., van Straten, A., & Rutters, F. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgz065 · Cited by 97
Sleep disorders related to nutrition and digestive diseases: a neglected clinical condition
Vernia, F., Ruscio, M. D., Ciccone, A. M., Viscido, A., Frieri, G., Stefanelli, G., & Latella, G. (2020) · International Journal of Medical Sciences · doi:10.7150/ijms.45512 · Cited by 96
Ten-Year Secular Trends in Sleep/Wake Patterns in Shanghai and Hong Kong School-Aged Children: A Tale of Two Cities
Wang, G.-H., Zhang, J.-H., Lam, S. P., Li, S., Jiang, Y., Sun, W.-Q., Chan, N., Kong, A., Zhang, Y.-T., Li, S.-H., et al. (2019) · Journal of Clinical Sleep Medicine (JCSM) · doi:10.5664/jcsm.7984 · Cited by 48
Increased Food Intake by Insufficient Sleep in Humans: Are We Jumping the Gun on the Hormonal Explanation?
Chaput, J., & St‐Onge, M. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00116 · Cited by 87
Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study
Sindi, S., Pérez, L. M., Vetrano, D. L., Triolo, F., Kåreholt, I., Sjöberg, L., Darin‐Mattsson, A., Kivipelto, M., Inzitari, M., & Calderón‐Larrañaga, A. (2020) · BMC Medicine · doi:10.1186/s12916-020-01846-w · Cited by 85
Association of healthy lifestyle including a healthy sleep pattern with incident type 2 diabetes mellitus among individuals with hypertension
Song, Z., Yang, R., Wang, W., Huang, N., Zhuang, Z., Han, Y., Qi, L., Xu, M., Tang, Y., & Huang, T. (2021) · Cardiovascular Diabetology · doi:10.1186/s12933-021-01434-z · Cited by 83
An integrative review of sleep for nutrition professionals
Golem, D. L., Martin-Biggers, J. T., Koenings, M. M., Davis, K. F., & Byrd-Bredbenner, C. (2014) · Advances in Nutrition · doi:10.3945/an.114.006809 · Cited by 77
Change in Sleep Duration and Type 2 Diabetes: The Whitehall II Study
Ferrie, J. E., Mika Kivimaki, B., Akbaraly, T. N., Tabák, Á. G., Abell, J. G., Smith, G. D., Virtanen, M., Meena Kumari, B., & Shipley, M. J. (2015) · Diabetes Care · doi:10.2337/dc15-0186 · Cited by 78
Sleep, Health, and Metabolism in Midlife Women and Menopause
Kravitz, H. M., Kazlauskaite, R., & Joffe, H. (2018) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2018.07.008 · Cited by 74
Saturation effects of the relationship between physical exercise and systemic immune inflammation index in the short-sleep population: a cross-sectional study
You, Y., Ablitip, A., Chen, Y., Ding, H., Chen, K., Cui, Y., & Ma, X. (2024) · BMC Public Health · doi:10.1186/s12889-024-19432-7 · Cited by 74
Pediatric sleep problems: A clinician's guide to behavioral interventions.
Meltzer, L. J., & Crabtree, V. M. (2015) · American Psychological Association eBooks · doi:10.1037/14645-000 · Cited by 74
Aiding sleep in type 2 diabetes: therapeutic considerations
Tan, X., van Egmond, L., Chapman, C. D., Cedernaes, J., & Benedict, C. (2018) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(17)30233-4 · Cited by 72
Mutant neuropeptide S receptor reduces sleep duration with preserved memory consolidation
Xing, L., Shi, G., Mostovoy, Y., Gentry, N. W., Fan, Z., McMahon, T., Kwok, P., Jones, C. R., Ptáček, L. J., & Fu, Y. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aax2014 · Cited by 69
Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems
Yu, X., Franks, N. P., & Wisden, W. (2018) · Frontiers in Neural Circuits · doi:10.3389/fncir.2018.00004 · Cited by 69
Association Between Inpatient Sleep Loss and Hyperglycemia of Hospitalization
DePietro, R. H., Knutson, K. L., Spampinato, L. M., Anderson, S. L. C., Meltzer, D. O., Cauter, E. V., & Arora, V. M. (2016) · Diabetes Care · doi:10.2337/dc16-1683 · Cited by 67
Relationships between sleep traits and lung cancer risk: a prospective cohort study in UK Biobank
Xie, J., Zhu, M., Ji, M., Fan, J., Huang, Y., Wei, X., Jiang, X., Xu, J., Yin, R. H., Wang, Y., et al. (2021) · SLEEP · doi:10.1093/sleep/zsab089 · Cited by 66
Joint associations of insomnia and sleep duration with prevalent diabetes: The H ispanic C ommunity H ealth S tudy/ S tudy of L atinos ( HCHS / SOL )
Feliciano, E. M. C., Dudley, K. A., Sotres‐Alvarez, D., Zee, P. C., Daviglus, M. L., Shah, N. A., Talavera, G. A., Gallo, L. C., Mattei, J., Qi, Q., et al. (2015) · Journal of Diabetes · doi:10.1111/1753-0407.12308 · Cited by 67
Association between sleep duration and metabolic syndrome: linear and nonlinear Mendelian randomization analyses
Liang, Y. Y., Chen, J., Peng, M., Zhou, J., Chen, X., Tan, X. W., Wang, N., Ma, H., Guo, L.-Y., Zhang, J., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-03920-2 · Cited by 63
Improving Cardiometabolic Health with Diet, Physical Activity, and Breaking Up Sitting: What about Sleep?
Vincent, G. E., Jay, S. M., Sargent, C., Vandelanotte, C., Ridgers, N. D., & Ferguson, S. A. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00865 · Cited by 62
A systems genetics resource and analysis of sleep regulation in the mouse
Diessler, S., Jan, M., Emmenegger, Y., Guex, N., Middleton, B., Skene, D. J., Ibberson, M. R., Burdet, F., Götz, L., Pagni, M., et al. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2005750 · Cited by 63
Detrimental Changes in Health during Menopause: The Role of Physical Activity
Hulteen, R. M., Marlatt, K. L., Allerton, T. D., & Lovre, D. (2023) · International Journal of Sports Medicine · doi:10.1055/a-2003-9406 · Cited by 68
Associations of time-restricted eating with health-related quality of life and sleep in adults: a secondary analysis of two pre-post pilot studies
Kesztyüs, D., Fuchs, M., Cermak, P., & Kesztyüs, T. (2020) · BMC Nutrition · doi:10.1186/s40795-020-00402-2 · Cited by 58
Sleep and future cardiovascular risk: prospective analysis from the English Longitudinal Study of Ageing
Jackowska, M., & Steptoe, A. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.02.530 · Cited by 56
Two Nights of Recovery Sleep Reverses the Effects of Short-term Sleep Restriction on Diabetes Risk
Broussard, J. L., Wroblewski, K., Kilkus, J. M., & Tasali, E. (2016) · Diabetes Care · doi:10.2337/dc15-2214 · Cited by 56
Association of Adverse Pregnancy Outcomes With Self-Reported Measures of Sleep Duration and Timing in Women Who Are Nulliparous
Facco, F., Parker, C. B., Hunter, S. M., Reid, K. J., Zee, P. C., Silver, R. M., Haas, D. M., Chung, J. M., Pien, G. W., Nhan‐Chang, C., et al. (2018) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.7534 · Cited by 58
Association of socioeconomic status with sleep disturbances in the Swiss population-based CoLaus study
Stringhini, S., Haba‐Rubio, J., Marques-Vidal, P. M., Waeber, G., Preisig, M., Guessous, I., Bovet, P., Vollenweider, P., Tafti, M., & Heinzer, R. C. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2014.12.014 · Cited by 56
Is sleep deprivation a contributor to obesity in children?
Chaput, J. (2015) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-015-0233-9 · Cited by 54
Effects of Healthy Lifestyles on Chronic Diseases: Diet, Sleep and Exercise
Oster, H., & Chaves, I. (2023) · Nutrients · doi:10.3390/nu15214627 · Cited by 53
Determinants of natural adult sleep: An umbrella review
Philippens, N., Janssen, E., Kremers, S., & Crutzen, R. (2022) · PLoS ONE · doi:10.1371/journal.pone.0277323 · Cited by 60
Predictors of sleep disorders among patients with type 2 diabetes mellitus
Gupta, S., & Wang, Z. (2016) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2016.06.009 · Cited by 48
Long-term changes in sleep duration, energy balance and risk of type 2 diabetes
Feliciano, E. M. C., Bhupathiraju, S. N., Li, Y., ROSNER, B. A., Redline, S. S., & Hu, F. B. (2015) · Diabetologia · doi:10.1007/s00125-015-3775-5 · Cited by 45
Hypoglycemia Unawareness—A Review on Pathophysiology and Clinical Implications
Hölzen, L., Schultes, B., Meyhöfer, S. M., & Meyhöfer, S. (2024) · Biomedicines · doi:10.3390/biomedicines12020391 · Cited by 44
Self-citation
Keeping Up With the Clock
Covassin, N., Singh, P., & Somers, V. K. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.06588 · Cited by 44
Determinants of poor sleep quality in elderly patients with diabetes mellitus, hyperlipidemia and hypertension in Singapore
Chiang, G. S. H., Sim, B. L. H., Lee, J. J. M., & Quah, J. H. M. (2018) · Primary Health Care Research & Development · doi:10.1017/s146342361800018x · Cited by 44
Neuroendocrine Control of Sleep
Smith, P. C., & Mong, J. A. (2019) · Current topics in behavioral neurosciences · doi:10.1007/7854_2019_107 · Cited by 45
Shorter Duration and Lower Quality Sleep Have Widespread Detrimental Effects on Developing Functional Brain Networks in Early Adolescence
Brooks, S. J., Katz, E. S., & Stamoulis, C. (2021) · Cerebral Cortex Communications · doi:10.1093/texcom/tgab062 · Cited by 44
Molecular mechanisms linking type 2 diabetes mellitus and late-onset Alzheimer's disease: A systematic review and qualitative meta-analysis
Lemche, E., Killick, R., Mitchell, J., Caton, P., Choudhary, P., & Howard, J. K. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106485 · Cited by 45
The impact of breaking up prolonged sitting on glucose metabolism and cognitive function when sleep is restricted
Vincent, G. E., Jay, S. M., Sargent, C., Kovac, K., Vandelanotte, C., Ridgers, N. D., & Ferguson, S. A. (2017) · Neurobiology of Sleep and Circadian Rhythms · doi:10.1016/j.nbscr.2017.09.001 · Cited by 42
Relationship between metabolic syndrome and objective masticatory performance in a Japanese general population: The Suita study
Kikui, M., Ono, T., Kokubo, Y., Kida, M., Kosaka, T., Yamamoto, M., Nokubi, T., Watanabe, M., Maeda, Y., & Miyamoto, Y. (2016) · Journal of Dentistry · doi:10.1016/j.jdent.2016.10.014 · Cited by 41
Long-term effects of sleep deprivation on neuronal activity in four hypothalamic areas
Fifel, K., Meijer, J. H., & Deboer, T. (2017) · Neurobiology of Disease · doi:10.1016/j.nbd.2017.10.005 · Cited by 41
Research Combining Physical Activity and Sleep: A Bibliometric Analysis
Memon, A. R., Vandelanotte, C., Olds, T., Duncan, M. J., & Vincent, G. E. (2019) · Perceptual and Motor Skills · doi:10.1177/0031512519889780 · Cited by 41
What ‘We’?
Lawford‐Smith, H. (2015) · Journal of Social Ontology · doi:10.1515/jso-2015-0008 · Cited by 44
Extracting Circadian and Sleep Parameters from Longitudinal Data in Schizophrenia for the Design of Pragmatic Light Interventions
Skeldon, A. C., Dijk, D., Meyer, N., & Wulff, K. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab124 · Cited by 42
Sleep Health
Vorster, A. P. A., Someren, E. J. W. V., Pack, A. I., Huber, R., Schmidt, M. H., & Bassetti, C. L. (2024) · Clinical and Translational Neuroscience · doi:10.3390/ctn8010008 · Cited by 51
Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium
Marinelli, M., Pappa, I., Bustamante, M., Bonilla, C., Bonilla, C., Suarez, A., Tiesler, C. M. T., Vilor‐Tejedor, N., Zafarmand, M. H., Álvarez‐Pedrerol, M., et al. (2016) · SLEEP · doi:10.5665/sleep.6170 · Cited by 42
Sleep Loss Disrupts Morning-to-Evening Differences in Human White Adipose Tissue Transcriptome
Wilms, B., Leineweber, E., Mölle, M., Chamorro, R., Pommerenke, C., Salinas, G., Sina, C., Lehnert, H., Oster, H., & Schmid, S. M. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-01663 · Cited by 41
Self-citation
Associations between actigraphy-assessed sleep, inflammatory markers, and insulin resistance in the Midlife Development in the United States (MIDUS) study
Kim, T. H., Carroll, J. E., An, S. K., Seeman, T. E., Namkoong, K., & Lee, E. (2016) · Sleep Medicine · doi:10.1016/j.sleep.2016.07.023 · Cited by 39
Coordinated human sleeping brainwaves map peripheral body glucose homeostasis
Vallat, R., Shah, V. D., & Walker, M. P. (2023) · Cell Reports Medicine · doi:10.1016/j.xcrm.2023.101100 · Cited by 39
Sleep’s contribution to memory formation
Lutz, N. D., Harkotte, M., & Jan Born, A. (2025) · Physiological Reviews · doi:10.1152/physrev.00054.2024 · Cited by 51
Changes in sleep EEG with aging in humans and rodents
Campos-Beltrán, D., & Marshall, L. (2021) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-021-02545-y · Cited by 38
The impact of sleep duration and sleep quality on glycaemic control in Asian population with type 2 diabetes mellitus: A systematic literature review and meta-analysis of observational studies
Azharuddin, M., Kapur, P., Adil, M., Ghosh, P., & Sharma, M. (2020) · Clinical Epidemiology and Global Health · doi:10.1016/j.cegh.2020.03.006 · Cited by 37
Sickness absenteeism is associated with sleep problems independent of sleep disorders: results of the 2016 Sleep Health Foundation national survey
Reynolds, A. C., Appleton, S., Gill, T. K., Taylor, A. W., McEvoy, R. D., Ferguson, S. A., & Adams, R. (2017) · Sleep Health · doi:10.1016/j.sleh.2017.06.003 · Cited by 40
Outcomes and clinical implications of intranasal insulin administration to the central nervous system
Santiago, J. C. P., & Hallschmid, M. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.03.007 · Cited by 37
Self-citation
Insomnia and obesity
Crönlein, T. (2016) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000284 · Cited by 37
Insomnia symptoms as a cause of type 2 diabetes Incidence: a 20 year cohort study
Green, M. J., Espie, C. A., Popham, F., Robertson, T., & Benzeval, M. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1268-4 · Cited by 36
Sleep Disturbances Are Mediators Between Socioeconomic Status and Health: a Scoping Review
Papadopoulos, D., Sosso, F. A. E., Khoury, T., & Surani, S. (2020) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-020-00378-x · Cited by 37
A multi-omics digital research object for the genetics of sleep regulation
Jan, M., Gobet, N., Diessler, S., Franken, P., & Xénarios, I. (2019) · Scientific Data · doi:10.1038/s41597-019-0171-x · Cited by 35
Severe chronic insomnia is not associated with higher body mass index
Crönlein, T., Langguth, B., Busch, V., Rupprecht, R., & Wetter, T. C. (2015) · Journal of Sleep Research · doi:10.1111/jsr.12294 · Cited by 34
Associations of Insomnia With Insulin Resistance Traits: A Cross-sectional and Mendelian Randomization Study
Wang, X., Zhao, C., Feng, H., Li, G., He, L., Yang, L., Liang, Y., Tan, X. W., Xu, Y., Cui, R., et al. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad089 · Cited by 34

Authors: Schmid, S. M., Hallschmid, M., & Schultes, B.
Affiliations: University of Cambridge (GB)
German Center for Diabetes Research (DE)
eSwiss Medical and Surgical Center (CH)
Corresponding author: Schultes, Bernd
ORCID: Hallschmid, Manfred
Schultes, Bernd
Venue: The Lancet Diabetes & Endocrinology
Publisher: Elsevier BV
Published: 2015-01
Volume: 3
Issue: 1
Pages: 52-62
ISSN: 2213-8587 (ISSN-L)
DOI: 10.1016/s2213-8587(14)70012-9
OpenAlex: W2145872904
Semantic Scholar: 847eb961d53b9fc39ac9795ecbe6de700a8252fc
Cited by: 328
References: 103
Citations by year: 2026: 8 · 2025: 35 · 2024: 24 · 2023: 17 · 2022: 33 · 2021: 28 · 2020: 32 · 2019: 29 · 2018: 30 · 2017: 23 · 2016: 29 · 2015: 28
FWCI: 4.06
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: The Lancet Diabetes & Endocrinology (publishedVersion)
PubMed (publishedVersion)
Site cant be reached (submittedVersion)
Funders: European Society of Endocrinology
Deutsche Forschungsgemeinschaft (SFB 654)
Bundesministerium für Bildung und Forschung
Helmholtz Association
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Keywords: sleep deprivation, short sleep duration, sleep disorders, obesity, type 2 diabetes, metabolic health, neuroendocrine system, appetite, dietary intake, energy expenditure, physical activity, sleep interventions
MeSH terms: Appetite, Eating, Glucose, Humans, Neurosecretory Systems, Obesity, Sleep Wake Disorders, Metabolic Syndrome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The metabolic burden of sleep loss

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks