Self-Powered, One-Stop, and Multifunctional Implantable Triboelectric Active Sensor for Real-Time Biomedical Monitoring
Abstract
Operation time of implantable electronic devices is largely constrained by the lifetime of batteries, which have to be replaced periodically by surgical procedures once exhausted, causing physical and mental suffering to patients and increasing healthcare costs. Besides the efficient scavenging of the mechanical energy of internal organs, this study proposes a self-powered, flexible, and one-stop implantable triboelectric active sensor (iTEAS) that can provide continuous monitoring of multiple physiological and pathological signs. As demonstrated in human-scale animals, the device can monitor heart rates, reaching an accuracy of ∼99%. Cardiac arrhythmias such as atrial fibrillation and ventricular premature contraction can be detected in real-time. Furthermore, a novel method of monitoring respiratory rates and phases is established by analyzing variations of the output peaks of the iTEAS. Blood pressure can be independently estimated and the velocity of blood flow calculated with the aid of a separate arterial pressure catheter. With the core-shell packaging strategy, monitoring functionality remains excellent during 72 h after closure of the chest. The in vivo biocompatibility of the device is examined after 2 weeks of implantation, proving suitability for practical use. As a multifunctional biomedical monitor that is exempt from needing an external power supply, the proposed iTEAS holds great potential in the future of the healthcare industry.
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Another TENG based self-powered implantable triboelectric active sensor is proposed to achieve in vivo continuous and real-time monitoring.
“In addition, another TENG based self-powered implantable triboelectric active sensor (iTEAS) is proposed to achieve in vivo continuous and real-time monitoring [Fig.2(m)].77”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [77]
Driven by the heartbeat and breathing motions of a living swine, the iTEAS produces an open circuit voltage of ∼10 V and a short circuit current of ∼4 μA.
“Driven by the heartbeat and breathing motions of a living swine, the iTEAS can produce an open circuit voltage of ∼10 V and a short circuit current of ∼4 µA.”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [77]
The iTEAS is able to continuously monitor physiological and pathological signs, including heartbeat rate, respiratory rate, and arrhythmia.
“In addition, the iTEAS is able to continuously monitor the physiological and pathological signs, including heartbeat rate, respiratory rate, and arrhythmia.”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [77]
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- Authors
- Ma, Y., Zheng, Q., Liu, Y., Shi, B., Xue, X., Ji, W., Liu, Z., Jin, Y., Zou, Y., An, Z., Zhang, W., Wang, X., Jiang, W., Xu, Z., Wang, Z. L., Li, Z., & Zhang, H.
- Affiliations
- Second Military Medical University (CN)
- Chinese Academy of Sciences (CN)
- Beihang University (CN)
- Georgia Institute of Technology (US)
- Corresponding author
- Wang, Zhong Lin
- Li, Zhou
- Zhang, Hao
- ORCID
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-09-15
- Volume
- 16
- Issue
- 10
- Pages
- 6042-6051
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2511382772
- Cited by
- 367
- References
- 43
- Citations by year
- 2026: 18 · 2025: 30 · 2024: 33 · 2023: 42 · 2022: 55 · 2021: 54 · 2020: 41 · 2019: 36 · 2018: 40 · 2017: 18
- FWCI
- 15.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nano Letters (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (30700157, 31571006, 81271707, 81370335, 81371692)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Physical Sciences › Engineering › Biomedical Engineering › Wireless Body Area Networks
- Keywords
- self-powered sensing, mechanical energy harvesting, arrhythmia detection, atrial fibrillation, premature ventricular contractions, heart rate monitoring, respiratory rate estimation, blood pressure estimation, blood flow velocity, biocompatibility, flexible electronics, real-time physiological monitoring
- MeSH terms
- Animals, Arrhythmias, Cardiac, Blood Pressure, Heart Rate, Humans, Monitoring, Physiologic, Electric Power Supplies, Prostheses and Implants
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