Challenges and Opportunities for Intravital Near-Infrared Fluorescence Imaging Technology in the Second Transparency Window

Near-infrared fluorophores for biomedical imaging

Hong, G., Antaris, A. L., & Dai, H. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0010 · Cited by 2,985

Second window for in vivo imaging

Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848

Imaging in the era of molecular oncology

Weissleder, R., & Pittet, M. J. (2008) · Nature · doi:10.1038/nature06917 · Cited by 2,364

The Essential Physics of Medical Imaging

Bushberg, J. T., Seibert, J. A., Leidholdt, E. M., Boone, J. M., & Goldschmidt, E. J. (2003) · Medical Physics · doi:10.1118/1.1585033 · Cited by 1,987

Going deeper than microscopy: the optical imaging frontier in biology

Ntziachristos, V. (2010) · Nature Methods · doi:10.1038/nmeth.1483 · Cited by 1,896

A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice

Welsher, K., Liu, Z., Sherlock, S. P., Robinson, J. T., Chen, Z., Daranciang, D., & Dai, H. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.294 · Cited by 1,287

Multifunctional in vivo vascular imaging using near-infrared II fluorescence

Hong, G., Lee, J. C., Robinson, J. T., Raaz, U., Xie, L., Huang, N. F., Cooke, J. P., & Dai, H. (2012) · Nature Medicine · doi:10.1038/nm.2995 · Cited by 995

Lifetime-engineered NIR-II nanoparticles unlock multiplexed in vivo imaging

Fan, Y., Wang, P., Lu, Y., Wang, R., Zhou, L., Zheng, X., Li, X., Piper, J. A., & Zhang, F. (2018) · Nature Nanotechnology · doi:10.1038/s41565-018-0221-0 · Cited by 795

Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window

Zhang, Y., Hong, G., Zhang, Y., Chen, G., Li, F., Dai, H., & Wang, Q. (2012) · ACS Nano · doi:10.1021/nn301218z · Cited by 765

Rare-earth-doped biological composites as in vivo shortwave infrared reporters

Naczynski, D. J., Tan, M. C., Zevon, M., Wall, B., Kohl, J., Kulesa, A., Chen, S., Roth, C. M., Riman, R. E., & Moghe, P. V. (2013) · Nature Communications · doi:10.1038/ncomms3199 · Cited by 759

In Vivo Fluorescence Imaging with Ag2S Quantum Dots in the Second Near‐Infrared Region

Hong, G., Robinson, J. T., Zhang, Y., Diao, S., Antaris, A. L., Wang, Q., & Dai, H. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201206059 · Cited by 744

Near-Infrared Photoluminescent Ag2S Quantum Dots from a Single Source Precursor

Du, Y., Xu, B., Fu, T., Cai, M., Li, F., Zhang, Y., & Wang, Q. (2010) · Journal of the American Chemical Society · doi:10.1021/ja909490r · Cited by 645

Ultrafast fluorescence imaging in vivo with conjugated polymer fluorophores in the second near-infrared window

Hong, G., Zou, Y., Antaris, A. L., Diao, S., Wu, D., Cheng, K., Zhang, X., Chen, C., Liu, B., He, Y., et al. (2014) · Nature Communications · doi:10.1038/ncomms5206 · Cited by 563

Bright Aggregation‐Induced‐Emission Dots for Targeted Synergetic NIR‐II Fluorescence and NIR‐I Photoacoustic Imaging of Orthotopic Brain Tumors

Sheng, Z., Guo, B., Hu, D., Xu, S., Wu, W., Liew, W. H., Yao, K., Jiang, J., Liu, C., Zheng, H., et al. (2018) · Advanced Materials · doi:10.1002/adma.201800766 · Cited by 445

In vivo real-time visualization of tissue blood flow and angiogenesis using Ag2S quantum dots in the NIR-II window

Li, C., Zhang, Y., Wang, M., Zhang, Y., Chen, G., Li, L., Wu, D., & Wang, Q. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.010 · Cited by 428

In Vivo Fluorescence Imaging in the Second Near-Infrared Window with Long Circulating Carbon Nanotubes Capable of Ultrahigh Tumor Uptake

Robinson, J. T., Hong, G., Liang, Y., Zhang, B., Yaghi, O. K., & Dai, H. (2012) · Journal of the American Chemical Society · doi:10.1021/ja303737a · Cited by 412

In vivo biosensing via tissue-localizable near-infrared-fluorescent single-walled carbon nanotubes

Iverson, N. M., Barone, P. W., Shandell, M., Trudel, L. J., Sen, S., Sen, F., Ivanov, V., Atolia, E., Farias, E., McNicholas, T. P., et al. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2013.222 · Cited by 379

Epitaxial Seeded Growth of Rare‐Earth Nanocrystals with Efficient 800 nm Near‐Infrared to 1525 nm Short‐Wavelength Infrared Downconversion Photoluminescence for In Vivo Bioimaging

Wang, R., Li, X., Zhou, L., & Zhang, F. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201407420 · Cited by 365

Controlled Synthesis of Ag2S Quantum Dots and Experimental Determination of the Exciton Bohr Radius

Zhang, Y., Liu, Y., Li, C., Chen, X., & Wang, Q. (2014) · The Journal of Physical Chemistry C · doi:10.1021/jp501266d · Cited by 272

Biodistribution, pharmacokinetics and toxicology of Ag2S near-infrared quantum dots in mice

Zhang, Y., Zhang, Y., Hong, G., He, W., Zhou, K., Yang, K., Li, F., Chen, G., Liu, Z., Dai, H., et al. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.01.089 · Cited by 254

Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes

Ghosh, D., Bagley, A. F., Na, Y. J., Birrer, M. J., Bhatia, S. N., & Belcher, A. M. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1400821111 · Cited by 251

Tracking of Transplanted Human Mesenchymal Stem Cells in Living Mice using Near‐Infrared Ag2S Quantum Dots

Chen, G., Tian, F., Zhang, Y., Zhang, Y., Li, C., & Wang, Q. (2014) · Advanced Functional Materials · doi:10.1002/adfm.201303263 · Cited by 214

Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery

Shou, K., Tang, Y., Chen, H., Chen, S., Zhang, L., Zhang, A., Fan, Q., Yu, A., & Cheng, Z. (2018) · Chemical Science · doi:10.1039/c8sc00206a · Cited by 199

Synthesis of InAs/CdSe/ZnSe Core/Shell1/Shell2 Structures with Bright and Stable Near-Infrared Fluorescence

Aharoni, A., Mokari, T., Popov, I., & Banin, U. (2006) · Journal of the American Chemical Society · doi:10.1021/ja056326v · Cited by 196

Chirality Enriched (12,1) and (11,3) Single-Walled Carbon Nanotubes for Biological Imaging

Diao, S., Hong, G., Robinson, J. T., Jiao, L., Antaris, A. L., Wu, J. Z., Choi, C. L., & Dai, H. (2012) · Journal of the American Chemical Society · doi:10.1021/ja307966u · Cited by 187

Detection of visible photons in CCD and CMOS: A comparative view

Magnan, P. (2003) · Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment · doi:10.1016/s0168-9002(03)00792-7 · Cited by 185

Preoperative Detection and Intraoperative Visualization of Brain Tumors for More Precise Surgery: A New Dual-Modality MRI and NIR Nanoprobe

Li, C., Cao, L., Zhang, Y., Yi, P., Wang, M., Tan, B., Deng, Z., Wu, D., & Wang, Q. (2015) · Small · doi:10.1002/smll.201500997 · Cited by 150

Real-time in vivo visualization of tumor therapy by a near-infrared-II Ag2S quantum dot-based theranostic nanoplatform

Hu, F., Li, C., Zhang, Y., Wang, M., Wu, D., & Wang, Q. (2015) · Nano Research · doi:10.1007/s12274-014-0653-2 · Cited by 126

Aqueous synthesis of glutathione-coated PbS quantum dots with tunable emission for non-invasive fluorescence imaging in the second near-infrared biological window (1000–1400 nm)

Nakane, Y., Tsukasaki, Y., Sakata, T., Yasuda, H., & Jin, T. (2013) · Chemical Communications · doi:10.1039/c3cc44000a · Cited by 120

Versatile Types of Inorganic/Organic NIR-IIa/IIb Fluorophores: From Strategic Design toward Molecular Imaging and Theranostics

Liu, Y., Li, Y., Koo, S., Sun, Y., Liu, Y., Liu, X., Pan, Y., Zhang, Z., Du, M., Lu, S., et al. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00553 · Cited by 537

Stable, Wavelength‐Tunable Fluorescent Dyes in the NIR‐II Region for In Vivo High‐Contrast Bioimaging and Multiplexed Biosensing

Lei, Z., Sun, C., Pei, P., Wang, S., Li, D., Zhang, X., & Zhang, F. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201904182 · Cited by 362

Gathering brings strength: How organic aggregates boost disease phototheranostics

Qi, J., Ou, H., Liu, Q., & Ding, D. (2021) · Aggregate · doi:10.1002/agt2.25 · Cited by 284

Semiconducting Polymer Dots with Dual‐Enhanced NIR‐IIa Fluorescence for Through‐Skull Mouse‐Brain Imaging

Zhang, Z., Fang, X., Liu, Z., Liu, H., Chen, D., He, S., Zheng, J., Yang, B., Qin, W., Zhang, X., et al. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201914397 · Cited by 242

Colloidal Alloyed Quantum Dots with Enhanced Photoluminescence Quantum Yield in the NIR-II Window

Yang, H., Li, R., Zhang, Y., Yu, M., Wang, Z., Liu, X., You, W., Tu, D., Sun, Z., Zhang, R., et al. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.0c13071 · Cited by 241