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Trans-Placental Transfer of Thirteen Perfluorinated Compounds and Relations with Fetal Thyroid Hormones

Kim, Sunmi, Choi, Kyungho, Ji, Kyunghee, Seo, Jihyeon, Kho, Younglim, Park, Jeongim, Kim, Sungkyoon, Park, Seokhwan, Hwang, Incheol, Jeon, Jongkwan, Yang, Hyeran, Giesy, John P.·2011·Environmental Science & Technology

DOI 10.1021/es202408a

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Abstract

While the results of animal studies have shown that perfluorinated compounds (PFCs) can modulate concentrations of thyroid hormones in blood, limited information is available on relationships between concentrations of PFCs in human blood serum and fetal thyroid hormones. The relationship between concentrations of PFCs in blood and fetal thyroid hormone concentrations or birth weight, and ratios of major PFCs between maternal and fetal serum were determined. Concentrations of PFCs were measured in blood serum of pregnant women (n = 44), fetal cord blood serum (n = 43) and breast milk (n = 35). Total concentrations of thyroxin (T4), triiodothyronin (T3) and thyroid stimulating hormone (TSH) in blood serum were also quantified. The ratios of major PFCs in maternal versus fetal serum were 1:1.93, 1.02, 0.72, and 0.48 for perfluorotridecanoic acid (PFTrDA), perfluorooctanoic acid (PFOA), perfluorohexane sulfonate (PFHxS), and perfluorooctane sulfonate (PFOS), respectively. Fetal PFOS, PFOA, PFTrDA and maternal PFTrDA were correlated with fetal total T4 concentrations, but after adjusting for major covariates, most of the relationships were no longer statistically significant. However, the significant negative correlations between maternal PFOS and fetal T3, and maternal PFTrDA and fetal T4 and T3 remained. Since thyroid hormones are crucial in the early development of the fetus, its clinical implication should be evaluated. Given the observed trans-placental transfer of PFCs, efforts should be also made to elucidate the exposure sources among pregnant women.

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Giesy, J. P., & Kannan, K. (2001) · Environmental Science & Technology · doi:10.1021/es001834k · Cited by 2,750
Self-citation
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
Lau, C., Anitole, K., Hodes, C., Lai, D., Pfahles-Hutchens, A., & Seed, J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm128 · Cited by 2,620
Polyfluoroalkyl Chemicals in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and Comparisons with NHANES 1999–2000
Calafat, A. M., Wong, L.-Y., Kuklenyik, Z., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10598 · Cited by 1,247
Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. I: Maternal and Prenatal Evaluations
Thibodeaux, J. R., Hanson, R. G., Rogers, J. M., Grey, B. E., Barbee, B. D., Richards, J. H., Butenhoff, J. L., Stevenson, L. A., & Lau, C. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg121 · Cited by 445
Polyfluorinated Compounds in the Atmosphere of the Atlantic and Southern Oceans: Evidence for a Global Distribution
Dreyer, A., Weinberg, I., Temme, C., & Ebinghaus, R. (2009) · Environmental Science & Technology · doi:10.1021/es9010465 · Cited by 230
Gestational and Lactational Exposure to Potassium Perfluorooctanesulfonate (K+PFOS) in Rats: Toxicokinetics, Thyroid Hormone Status, and Related Gene Expression
Chang, S.-C., Ehresman, D. J., Bjork, J. A., Wallace, K. B., Parker, G. A., Stump, D. G., & Butenhoff, J. L. (2009) · Reproductive Toxicology · doi:10.1016/j.reprotox.2009.01.005 · Cited by 118

Show all 6 references

Research works printed but not linked: 36

Renner R., 2001, Environ. Sci. Technol., 35, 154A, 10.1021/es012317k · DOI · Paper page
Prevedouros K., 2006, Environ. Sci. Technol., 40, 32, 10.1021/es0512475 · DOI · Paper page
Stock N. L., 2007, Environ. Sci. Technol., 41, 3529, 10.1021/es062709x · DOI · Paper page
Fromme H., 2009, Int.J. Hyg. Environ. Health, 212, 239, 10.1016/j.ijheh.2008.04.007 · DOI · Paper page
Fei C., 2007, Environ. Health Perspect., 115, 1677, 10.1289/ehp.10506 · DOI · Paper page
Tittlemier S. A., 2004, Organohalogen Compd., 66, 4009
Monroy R., 2008, Environ. Res., 108, 56, 10.1016/j.envres.2008.06.001 · DOI · Paper page
Apelberg B. J., 2007, Environ. Health Perspect., 115, 1670, 10.1289/ehp.10334 · DOI · Paper page
Tao L., 2008, Environ. Sci. Technol., 42, 8597, 10.1021/es801875v · DOI
Karrman A., 2007, Environ. Health Perspect., 115, 226, 10.1289/ehp.9491 · DOI · Paper page
Olsen G. W., 2007, Chemosphere, 68, 105, 10.1016/j.chemosphere.2006.12.031 · DOI
Washino N., 2009, Environ. Health Perspect., 117, 660, 10.1289/ehp.11681 · DOI · Paper page
Inoue K., 2004, Environ. Health Perspect., 112, 1204, 10.1289/ehp.6864 · DOI · Paper page
Butenhoff J., 2002, Toxicol. Sci., 69, 244, 10.1093/toxsci/69.1.244 · DOI · Paper page
Lau C., 2003, Toxicol. Sci., 74, 382, 10.1093/toxsci/kfg122 · DOI · Paper page
Weiss J. M., 2009, Toxicol. Sci., 109, 206, 10.1093/toxsci/kfp055 · DOI · Paper page
Sakr C. J., 2007, J. Occup. Environ. Med., 49, 1086, 10.1097/JOM.0b013e318156eca3 · DOI
Olsen G. W., 2007, Int. Arch. Occup. Environ. Health, 81, 231, 10.1007/s00420-007-0213-0 · DOI · Paper page
Melzer D., 2010, Environ. Health Perspect., 118, 686, 10.1289/ehp.0901584 · DOI · Paper page
Bloom M. S., 2009, Physiol. Behav., 99, 240, 10.1016/j.physbeh.2009.02.005 · DOI
Porterfield S. P., 1994, Environ. Health Perspect., 102, 125
Hansen K. J., 2002, Environ. Sci. Technol., 36, 1681, 10.1021/es010780r · DOI · Paper page
Reagen W. K., 2008, Anal .Chim. Acta., 628, 214, 10.1016/j.aca.2008.09.029 · DOI
Naile J. E., 2010, Toxicol. Environ. Chem., 92, 1219, 10.1080/02772240903397556 · DOI
Volkel W., 2008, Int. J. Hyg. Environ. Health, 211, 440, 10.1016/j.ijheh.2007.07.024 · DOI
National Institute of Occupational Safety and Health (NIOSH), 1995, Guidelines for Air Sampling and Analytical Method Development and Evaluation
Keller J. M., 2010, Anal. Bioanal. Chem., 397, 439, 10.1007/s00216-009-3222-x · DOI
Oken E., 2009, J. Clin. Endocrinol. Metab., 94, 497, 10.1210/jc.2008-0936 · DOI
Lau C., 2003, Toxicol. Sci., 74, 382, 10.1093/toxsci/kfg122 · DOI · Paper page
Yu W. G., 2009, Environ. Sci. Technol., 43, 8416, 10.1021/es901602d · DOI
Jones P. D., 2003, Environ. Toxicol. Chem., 22, 2639, 10.1897/02-553 · DOI · Paper page
Midasch O., 2007, Int. Arch. Occup. Environ. Health, 80, 643, 10.1007/s00420-006-0165-9 · DOI · Paper page
Luebker D. J., 2002, Toxicology, 176, 175, 10.1016/S0300-483X(02)00081-1 · DOI · Paper page
Woollett L. A., 2001, Curr. Opin. Lipidol., 12, 305, 10.1097/00041433-200106000-00010 · DOI
So M. K., 2006, Environ. Sci. Technol., 40, 2924, 10.1021/es060031f · DOI · Paper page
Thayer K., 2002, Perfluorinated Chemicals: Justification for Inclusion of This Chemical Class in the National Report on Human Exposure to Environmental Chemicals

Risk to human health related to the presence of perfluoroalkyl substances in food
Panel), E. P. O. C. I. T. F. C. (. C., Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Grasl‐Kraupp, B., Hogstrand, C., Hoogenboom, L. (., Leblanc, J., et al. (2020) · EFSA Journal · doi:10.2903/j.efsa.2020.6223 · Cited by 989
Early Life Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Latent Health Outcomes: A Review Including the Placenta as a Target Tissue and Possible Driver of Peri- and Postnatal Effects
Blake, B. E., & Fenton, S. E. (2020) · Toxicology · doi:10.1016/j.tox.2020.152565 · Cited by 499
The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Human Evidence for PFOA Effects on Fetal Growth
Johnson, P. I., Sutton, P., Atchley, D. S., Koustas, E., Lam, J., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307893 · Cited by 449
The Navigation Guide Systematic Review Methodology: A Rigorous and Transparent Method for Translating Environmental Health Science into Better Health Outcomes
Woodruff, T. J., & Sutton, P. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307175 · Cited by 427
Exposure to Perfluorinated Alkyl Substances and Health Outcomes in Children: A Systematic Review of the Epidemiologic Literature
Rappazzo, K., Coffman, E., & Hines, E. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph14070691 · Cited by 405
The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Nonhuman Evidence for PFOA Effects on Fetal Growth
Koustas, E., Lam, J., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307177 · Cited by 349
Consideration of pathways for immunotoxicity of per-and polyfluoroalkyl substances (PFAS)
Ehrlich, V., Bil, W., Vandebriel, R., Granum, B., Luijten, M., Lindeman, B., Grandjean, P., Kaiser, A.-M., Hauzenberger, I., Hartmann, C., et al. (2023) · Environmental Health · doi:10.1186/s12940-022-00958-5 · Cited by 318
Per- and polyfluorinated substances (PFASs): Environmental challenges
Krafft, M. P., & Riess, J. G. (2015) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2015.07.004 · Cited by 294
Exposure to perfluoroalkyl substances and thyroid function in pregnant women and children: a systematic review of epidemiologic studies
Ballesteros, V., Costa, O., Iñiguez, C., Fletcher, T., Ballester, F., & Lopez-Espinosa, M.-J. (2017) · Environment International · doi:10.1016/j.envint.2016.10.015 · Cited by 242
Prenatal exposure to per-and polyfluoroalkyl substances (PFASs) and association between the placental transfer efficiencies and dissociation constant of serum proteins–PFAS complexes
Gao, K., Zhuang, T., Liu, X., Fu, J., Zhang, J., Fu, J., Wang, L., Zhang, A., Liang, Y., Song, M., et al. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b00715 · Cited by 231
The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Integration of Animal and Human Evidence for PFOA Effects on Fetal Growth
Lam, J., Koustas, E., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307923 · Cited by 214
Interspecies differences in perfluoroalkyl substances (PFAS) toxicokinetics and application to health-based criteria
Pizzurro, D. M., Seeley, M., Kerper, L. E., & Beck, B. D. (2019) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2019.05.008 · Cited by 206
Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Maternal and Neonatal Thyroid Function in the Project Viva Cohort: A Mixtures Approach
Preston, E. V., Webster, T. F., Claus Henn, B., McClean, M. D., Gennings, C., Oken, E., Rifas-Shiman, S. L., Pearce, E. N., Calafat, A. M., Fleisch, A. F., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105728 · Cited by 169
Association between Maternal Serum Perfluoroalkyl Substances during Pregnancy and Maternal and Cord Thyroid Hormones: Taiwan Maternal and Infant Cohort Study
Wang, Y., Rogan, W. J., Chen, P.-C., Lien, G.-W., Chen, H.-Y., Tseng, Y.-C., Longnecker, M. P., & Wang, S.-L. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1306925 · Cited by 162
Associations between Perfluoroalkyl acids (PFASs) and maternal thyroid hormones in early pregnancy: A population-based cohort study
Webster, G. M., Venners, S. A., Mattman, A., & Martin, J. W. (2014) · Environmental Research · doi:10.1016/j.envres.2014.06.012 · Cited by 145
Early life exposure to per- and polyfluoroalkyl substances (PFASs): a critical review
Winkens, K., Vestergren, R., Berger, U., & Cousins, I. T. (2017) · Emerging Contaminants · doi:10.1016/j.emcon.2017.05.001 · Cited by 145
Effects of perfluoroalkyl acids on the function of the thyroid hormone and the aryl hydrocarbon receptor
Long, M., Ghisari, M., & Bonefeld-Jørgensen, E. C. (2013) · Environmental Science and Pollution Research · doi:10.1007/s11356-013-1628-7 · Cited by 144
Development of PBPK models for PFOA and PFOS for human pregnancy and lactation life stages
Loccisano, A. E., Longnecker, M. P., Campbell, J. L., Andersen, M. E., & Clewell, H. J. (2013) · Journal of Toxicology and Environmental Health, Part A · doi:10.1080/15287394.2012.722523 · Cited by 141
Transfer of perfluoroalkyl substances from mother to fetus in a Spanish birth cohort
Manzano-Salgado, C. B., Casas, M., Lopez-Espinosa, M.-J., Ballester, F., Basterrechea, M., Grimalt, J. O., Jiménez, A.-M., Kraus, T., Schettgen, T., Sunyer, J., et al. (2015) · Environmental Research · doi:10.1016/j.envres.2015.07.020 · Cited by 139
Cumulative Chemical Exposures During Pregnancy and Early Development
Mitro, S. D., Johnson, T., & Zota, A. R. (2015) · Current Environmental Health Reports · doi:10.1007/s40572-015-0064-x · Cited by 120
Maternal plasma per- and polyfluoroalkyl substance concentrations in early pregnancy and maternal and neonatal thyroid function in a prospective birth cohort: project viva (USA)
Preston, E. V., Webster, T. F., Oken, E., Claus Henn, B., McClean, M. D., Rifas-Shiman, S. L., Pearce, E. N., Braverman, L. E., Calafat, A. M., Ye, X., et al. (2018) · Environmental Health Perspectives · doi:10.1289/ehp2534 · Cited by 105
The transplacental transfer efficiency of per- and polyfluoroalkyl substances (PFAS): a first meta-analysis
Appel, M., Forsthuber, M., Ramos, R., Widhalm, R., Granitzer, S., Uhl, M., Hengstschläger, M., Stamm, T., & Gundacker, C. (2022) · Journal of Toxicology and Environmental Health, Part B · doi:10.1080/10937404.2021.2009946 · Cited by 104
Physico-chemical properties and gestational diabetes predict transplacental transfer and partitioning of perfluoroalkyl substances
Eryasa, B., Grandjean, P., Nielsen, F., Valvi, D., Zmirou-Navier, D., Sunderland, E., Weihe, P., & Oulhote, Y. (2019) · Environment International · doi:10.1016/j.envint.2019.05.068 · Cited by 98
Perfluoroalkyl substances exposure and thyroid hormones in humans: epidemiological observations and implications
Lee, J. E., & Choi, K. (2017) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2017.22.1.6 · Cited by 92
Self-citation
Historical human exposure to perfluoroalkyl acids in the United States and Australia reconstructed from biomonitoring data using population-based pharmacokinetic modelling
Gomis, M. I., Vestergren, R., MacLeod, M., Mueller, J. F., & Cousins, I. T. (2017) · Environment International · doi:10.1016/j.envint.2017.08.002 · Cited by 85
Perfluoroalkyl Chemicals in Neurological Health and Disease: Human Concerns and Animal Models
Piekarski, D., Diaz, K., & McNerney, M. (2020) · NeuroToxicology · doi:10.1016/j.neuro.2020.01.001 · Cited by 76
Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes
McGlinchey, A., Sinioja, T., Lamichhane, S., Sen, P., Bodin, J., Siljander, H., Dickens, A. M., Geng, D., Carlsson, C., Duberg, D., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105935 · Cited by 61
Influence of salinity and temperature on uptake of perfluorinated carboxylic acids (PFCAs) by hydroponically grown wheat (Triticum aestivum L.)
Zhao, H., Qu, B., Guan, Y., Jiang, J., & Chen, X. (2016) · SpringerPlus · doi:10.1186/s40064-016-2016-9 · Cited by 54
Neurodevelopmental and Metabolomic Responses from Prenatal Coexposure to Perfluorooctanesulfonate (PFOS) and Methylmercury (MeHg) in Sprague-Dawley Rats
Reardon, A. J. F., Karathra, J., Ribbenstedt, A., Benskin, J. P., MacDonald, A. M., Kinniburgh, D. W., Hamilton, T. J., Fouad, K., & Martin, J. W. (2019) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.9b00192 · Cited by 40
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(2022) · PubMed · Cited by 17

Authors: Kim, S., Choi, K., Ji, K., Seo, J., Kho, Y., Park, J., Kim, S., Park, S., Hwang, I., Jeon, J., Yang, H., & Giesy, J. P.
Venue: Environmental Science & Technology
Publisher: American Chemical Society (ACS)
Published: 2011-08-12
Volume: 45
Issue: 17
Pages: 7465-7472
ISSN: 0013-936X (ISSN-L)
1520-5851
DOI: 10.1021/es202408a
OpenAlex: W2001246172
Cited by: 240
References: 6
FWCI: 10.06
Type: journal article
Language: en
Open access: closed

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Trans-Placental Transfer of Thirteen Perfluorinated Compounds and Relations with Fetal Thyroid Hormones

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