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Cited by 621

The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.

Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo

Yu, Fabiao, Li, Peng, Wang, Bingshuai, Han, Keli·2013·Journal of the American Chemical Society

Abstract

The redox homeostasis between peroxynitrite and glutathione is closely associated with the physiological and pathological processes, e.g. vascular tissue prolonged relaxation and smooth muscle preparations, attenuation hepatic necrosis, and activation matrix metalloproteinase-2. We report a near-infrared fluorescent probe based on heptamethine cyanine, which integrates with telluroenzyme mimics for monitoring the changes of ONOO(-)/GSH levels in cells and in vivo. The probe can reversibly respond to ONOO(-) and GSH and exhibits high selectivity, sensitivity, and mitochondrial target. It is successfully applied to visualize the changes of redox cycles during the outbreak of ONOO(-) and the antioxidant GSH repair in cells and animal. The probe would provide a significant advance on the redox events involved in the cellular redox regulation.

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Crossref · 10.1021/ja401360a

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Metadata

Authors
Yu, F., Li, P., Wang, B., & Han, K.
Venue
Journal of the American Chemical Society
Published
2013-05-08
Volume
135
Issue
20
Pages
7674-7680
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2321766707
Cited by
621
References
73
FWCI
19.84
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.