Quality of Life in Persons with Irritable Bowel Syndrome (Development and Validation of a New Measure)

Patrick, Donald L.; Drossman, Douglas A.; Frederick, Ihunnaya O.; Dicesare, Joseph; Puder, Katherine L.

doi:10.1023/a:1018831127942

Cited by 761Gastrointestinal motility and disordersAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesInfant Health and Development

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Quality of Life in Persons with Irritable Bowel Syndrome (Development and Validation of a New Measure)

Patrick, Donald L., Drossman, Douglas A., Frederick, Ihunnaya O., Dicesare, Joseph, Puder, Katherine L.·1998·Digestive Diseases and Sciences

DOI 10.1023/a:1018831127942

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Abstract

How irritable bowel syndrome (IBS) and its treatment affect quality of life (QOL) is important. To develop a quality-of-life measure specific to irritable bowel syndrome, items were generated using a conceptual model and qualitative interviews with persons diagnosed using the Rome criteria. Symptom frequency and bothersomeness indices were created. Psychometric evaluation methods involved an initial cross-sectional survey followed by a repeat survey. The resulting 34-item measure demonstrated high internal consistency (Cronbach's alpha = 0.95) and high reproducibility (ICC = 0.86) with average time of seven days (SD = 1). For discriminant validity: number of symptoms (P < 0.05), self-reported severity of symptoms (P < 0.001), and the functional bowel disorder severity index (P < 0.001) significantly predicted IBS-QOL scores. Convergent validity and analyses confirmed predictions that scores are more closely related to psychological well-being (0.45) than to function (0.36). We conclude this measure meets established psychometric criteria for reliability and validity; testing of its responsiveness is warranted.

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The IBS-QOL scale is responsive to therapeutic change and has high test-retest reliability.
“Changes in physical and psychosocial functioning as a result of IBS were measured with the IBS-Quality of Life (IBS-QOL) scale, a 34-item scale that is responsive to therapeutic change (Drossman et al., 2000), and has high test-retest reliability (Patrick et al., 1998).”
From Therapeutic mechanisms of a mindfulness-based treatment for IBS: effects on visceral sensitivity, catastrophizing, and affective processing of pain sensations. (2012) · cites this paper as Patrick et al., 1998
The IBS-QOL shows high internal consistency (Cronbach's alpha = .95) and test-retest reliability (r = .86).
“The IBS-QOL shows high internal consistency (Chronbach's α = .95) and test-retest reliability (r = .86) [46].”
From Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: A randomized controlled trial (2011) · cites this paper as [46]

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Agarwal, N., & Spiegel, B. M. R. (2011) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2010.12.013 · Cited by 166
Design of treatment trials for functional gastrointestinal disorders
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Self-citation
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Method
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Self-citation
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Self-citation
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Self-citation
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MethodInfluential
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Self-citation
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Self-citation
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Self-citation
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Self-citation

Authors: Patrick, D. L., Drossman, D. A., Frederick, I. O., Dicesare, J., & Puder, K. L.
Affiliations: University of Washington (US)
ORCID: Patrick, Donald L.
Drossman, Douglas A.
Venue: Digestive Diseases and Sciences
Publisher: Springer Science and Business Media LLC
Published: 1998-02
Volume: 43
Issue: 2
Pages: 400-411
ISSN: 0163-2116 (ISSN-L)
1573-2568
DOI: 10.1023/a:1018831127942
OpenAlex: W1532990492
Cited by: 761
References: 26
Citations by year: 2026: 41 · 2025: 44 · 2024: 43 · 2023: 41 · 2022: 54 · 2021: 44 · 2020: 33 · 2019: 31 · 2018: 41 · 2017: 24 · 2016: 36 · 2015: 33 · 2014: 37 · 2013: 28 · 2012: 27
FWCI: 10.55
Type: journal article
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Digestive Diseases and Sciences (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
Keywords: irritable bowel syndrome, quality of life, IBS-QOL, psychometric validation, symptom frequency, Rome criteria, psychological well-being, reproducibility
MeSH terms: Adult, Colonic Diseases, Functional, Female, Health Status Indicators, Humans, Male, Middle Aged, Psychometrics, Quality of Life, Reproducibility of Results

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Quality of Life in Persons with Irritable Bowel Syndrome (Development and Validation of a New Measure)

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