Bupropion improves attention but does not affect impulsive behavior in healthy young adults.
Open accessAbstract
Bupropion is an effective abstinence aid for cessation of smoking and possibly other drug use as well. There is evidence that bupropion improves attention and impulse control in certain patient populations, and improvements in these processes could mediate its efficacy as an abstinence aid. In the present study, we tested the effects of acute bupropion on measures of attention and impulsivity in healthy adults with d-amphetamine included as a positive control. Twenty-two nonsmokers (11 women) and 11 smokers (4 women) completed four 4-hr sessions where they received placebo, bupropion (150 or 300 mg), or d-amphetamine (20 mg) in capsules. Ninety minutes after capsule administration, participants were tested on attention with a simple reaction time task (SRT) and on impulsivity with the stop task, a delay and probability discounting task (DPD), and the balloon analogue risk task (BART). Participants also completed mood questionnaires during sessions. Bupropion (150 mg) decreased lapses in attention on the SRT, but did not affect performance on the stop task, DPD, or BART. Amphetamine decreased lapses in attention and speeded sensory motor processing time on the SRT but did not significantly affect responding on the stop task or DPD. On the BART, d-amphetamine tended to decrease risk taking in men but increased risk taking in women. Bupropion (300 mg) and d-amphetamine increased ratings of arousal. These results suggest that bupropion improves attention without affecting impulsive behavior in healthy adults. Improvements in attention may contribute to the effectiveness of bupropion as a pharmacotherapy for smoking.
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Bupropion has been shown to improve sustained attention in youth with ADHD and healthy adults.
“Bupropion, a NE and DA reuptake inhibitor approved as an antidepressant has likewise been shown to improve sustained attention in youth with ADHD114 and healthy adults115.”
From Paying attention to attention in depression (2019) · cites this paper as [115]
Evidence from acute pharmacological interventions supports greater sensitivity of real-time tasks to manipulations likely to induce changes in state-impulsivity.
“Evidence from acute pharmacological interventions with psychomotor stimulants and suppressants supports the greater sensitivity of real-time tasks to manipulations likely to induce changes in state-impulsivity”
From DAT1 and COMT effects on delay discounting and trait impulsivity in male adolescents with attention deficit/hyperactivity disorder and healthy controls (2010) · cites this paper as Acheson and de Wit, 2008
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Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Insensitivity to future consequences following damage to human prefrontal cortex
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994) · Cognition · doi:10.1016/0010-0277(94)90018-3 · Cited by 6,128 · see citing works
The Michigan Alcoholism Screening Test: The Quest for a New Diagnostic Instrument
Selzer, M. L. (1971) · American Journal of Psychiatry · doi:10.1176/ajp.127.12.1653 · Cited by 3,485 · see citing works
Structured clinical interview for DSM-IV axis I disorders : SCID-I : clinical version : scoresheet
First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (1997) · American Psychiatric Press eBooks · Cited by 3,101 · see citing works
Specious reward: A behavioral theory of impulsiveness and impulse control.
Ainslie, G. (1975) · Psychological Bulletin · doi:10.1037/h0076860 · Cited by 2,708 · see citing works
Evaluation of a behavioral measure of risk taking: The balloon analogue risk task (BART)
Lejuez, C. W., Read, J. P., Kahler, C. W., Richards, J. B., Ramsey, S. E., Stuart, G. L., Strong, D. R., & Brown, R. A. (2002) · Journal of Experimental Psychology: Applied · doi:10.1037/1076-898x.8.2.75 · Cited by 2,336 · see citing works
Falk, J. L. (1973) · Contemporary Psychology · doi:10.1037/0011818 · Cited by 2,288 · see citing works
On the ability to inhibit simple and choice reaction time responses: A model and a method.
Logan, G. D., Cowan, W. B., & Davis, K. A. (1984) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037//0096-1523.10.2.276 · Cited by 1,537 · see citing works
AREA UNDER THE CURVE AS A MEASURE OF DISCOUNTING
Myerson, J., Green, L., & Warusawitharana, M. (2001) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.2001.76-235 · Cited by 1,507 · see citing works
Impulsivity as a determinant and consequence of drug use: a review of underlying processes
de Wit, H. (2009) · Addiction Biology · doi:10.1111/j.1369-1600.2008.00129.x · Cited by 1,415 · see citing works
Martin, W. R., Sloan, J. W., SAPIRA, J. D., & Jasinski, D. R. (1971) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt1971122part1245 · Cited by 945 · see citing works
DELAY OR PROBABILITY DISCOUNTING IN A MODEL OF IMPULSIVE BEHAVIOR: EFFECT OF ALCOHOL
Richards, J. B., Zhang, L., Mitchell, S. H., & de Wit, H. (1999) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1999.71-121 · Cited by 792 · see citing works
Lejuez, C. W., Aklin, W. M., Zvolensky, M. J., & Pedulla, C. M. (2003) · Journal of Adolescence · doi:10.1016/s0140-1971(03)00036-8 · Cited by 591 · see citing works
The balloon analogue risk task (BART) differentiates smokers and nonsmokers.
Lejuez, C. W., Aklin, W. M., Jones, H. A., Richards, J. B., Strong, D. R., Kahler, C. W., & Read, J. P. (2003) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.11.1.26 · Cited by 523 · see citing works
Bupropion is a nicotinic antagonist
Slemmer, J. E., Martin, B. R., & Damaj, M. I. (2000) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38905-0 · Cited by 509 · see citing works
The need for speed: an update on methamphetamine addiction
Barr, A. M., Panenka, W. J., MacEwan, G. W., Thornton, A. E., Lang, D. J., Honer, W. G., & Lecomte, T. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0635 · Cited by 438 · see citing works
Acute administration of d-amphetamine decreases impulsivity in healthy volunteers
de Wit, H. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00343-3 · Cited by 436 · see citing works
Investigating the neurocognitive deficits associated with chronic drug misuse
Rogers, R. D., & Robbins, T. W. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00204-x · Cited by 344 · see citing works
de Wit, H., Flory, J. D., Acheson, A., McCloskey, M. S., & Manuck, S. B. (2006) · Personality and Individual Differences · doi:10.1016/j.paid.2006.06.026 · Cited by 336 · see citing works
Self-citationLundqvist, T. (2005) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2005.02.017 · Cited by 331 · see citing works
Evaluation of behavioral measures of risk taking propensity with inner city adolescents
Aklin, W. M., Lejuez, C. W., Zvolensky, M. J., Kahler, C. W., & Gwadz, M. (2005) · Behaviour Research and Therapy · doi:10.1016/j.brat.2003.12.007 · Cited by 320 · see citing works
Duration of Cognitive Impairment After Sports Concussion
Bleiberg, J., Cernich, A. N., Cameron, K. L., Sun, W., Peck, K. Y., Ecklund, L. J., Reeves, C. D., Uhorchak, C. J., Sparling, M. B., & Warden, D. L. (2004) · Neurosurgery · doi:10.1227/01.neu.0000118820.33396.6a · Cited by 319 · see citing works
Giordano, L., Bickel, W., Loewenstein, G., Jacobs, E., Marsch, L., & Badger, G. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1159-2 · Cited by 294 · see citing works
Effects of d-Amphetamine and alcohol on a measure of behavioral inhibition in rats.
Feola, T. W., de Wit, H., & Richards, J. B. (2000) · Behavioral Neuroscience · doi:10.1037/0735-7044.114.4.838 · Cited by 278 · see citing works
The effect of bupropion on nicotine craving and withdrawal
Shiffman, S. S., Johnston, J. A., Khayrallah, M. A., Elash, C. A., Gwaltney, C. J., Paty, J. A., Gnys, M., Evoniuk, G. E., & DeVeaugh-Geiss, J. (2000) · Psychopharmacology · doi:10.1007/s002130050022 · Cited by 260 · see citing works
Recommendation for the assessment of tobacco craving and withdrawal in smoking cessation trials
Shiffman, S., West, R., & Gilbert, D. (2004) · Nicotine & Tobacco Research · doi:10.1080/14622200410001734067 · Cited by 255 · see citing works
Bupropion versus Methylphenidate in the Treatment of Attention-Deficit Hyperactivity Disorder
BARRICKMAN, L. L., PERRY, P. J., ALLEN, A. J., KUPERMAN, S., ARNDT, S. V., HERRMANN, K. J., & SCHUMACHER, E. (1995) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199505000-00017 · Cited by 254 · see citing works
Discounting of delayed hypothetical money, alcohol, and food
Odum, A. L., & Rainaud, C. P. (2003) · Behavioural Processes · doi:10.1016/s0376-6357(03)00145-1 · Cited by 250 · see citing works
Field, M., Santarcangelo, M., Sumnall, H., Goudie, A., & Cole, J. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0385-4 · Cited by 250 · see citing works
Bupropion for the treatment of methamphetamine dependence
Elkashef, A. M., Rawson, R. A., Anderson, A. L., Li, S.-H., Holmes, T., Smith, E. V., Chiang, N., Kahn, R., Vocci, F., Ling, W., et al. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301481 · Cited by 234 · see citing works
Fraser, H. F., Horn, G. D. V., Martin, W. R., Wolbach, A. B., & Isbell, H. (1961) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)26118-3 · Cited by 234 · see citing works
Cryan, J. F., Bruijnzeel, A. W., Skjei, K. L., & Markou, A. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1445-7 · Cited by 223 · see citing works
Understanding the health impact of alcohol dependence
Cargiulo, T. P. (2007) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp060647 · Cited by 219 · see citing works
Reward discounting as a measure of impulsive behavior in a psychiatric outpatient population.
Crean, J., de Wit, H., & Richards, J. (2000) · Experimental and clinical psychopharmacology · doi:10.1037//1064-1297.8.2.155 · Cited by 218 · see citing works
Drug preference and mood in humans: Diazepam
Johanson, C. E., & UHLENHUTH, E. H. (1980) · Psychopharmacology · doi:10.1007/bf00433061 · Cited by 211 · see citing works
Effects of sleep deprivation on impulsive behaviors in men and women
Acheson, A., Richards, J. B., & de Wit, H. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.03.020 · Cited by 204 · see citing works
Self-citationSmoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain
Miksys, S. L. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00136-9 · Cited by 198 · see citing works
Wilens, T. E., Haight, B. R., Horrigan, J. P., Hudziak, J. J., Rosenthal, N. E., Connor, D. F., Hampton, K. D., Richard, N. E., & Modell, J. G. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.01.027 · Cited by 193 · see citing works
Review of bupropion for smoking cessation
RICHMOND, R. L., & Zwar, N. A. (2003) · Drug and Alcohol Review · doi:10.1080/09595230100100642 · Cited by 170 · see citing works
Dual determinants of drug use in humans: reward and impulsivity.
de Wit, H., & Richards, J. B. (2004) · PubMed · Cited by 168 · see citing works
A multicenter trial of bupropion for cocaine dependence in methadone-maintained patients
Margolin, A., Kosten, T. R., Avants, S. K., Wilkins, J., Ling, W., Beckson, M., Arndt, I. O., Cornish, J., Ascher, J. A., Li, S.-H., et al. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(95)01198-6 · Cited by 168 · see citing works
Poling, J. C., Oliveto, A. H., Petry, N. M., Sofuoglu, M., Gonsai, K., Gonzalez, G. M., Martell, B. A., & Kosten, T. R. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.2.219 · Cited by 167 · see citing works
Bupropion Reduces Methamphetamine-Induced Subjective Effects and Cue-Induced Craving
Newton, T. F., Roache, J. D., Garza, R. D. L., FONG, T. W., Wallace, C. L., Li, S.-H., Elkashef, A. M., Chiang, N., & Kahn, R. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300979 · Cited by 163 · see citing works
Bruijnzeel, A. W., & Markou, A. (2003) · Synapse · doi:10.1002/syn.10242 · Cited by 143 · see citing works
MDMA use and neurocognition: a meta-analytic review
Kalechstein, A. D., Garza, R. D. L., Mahoney, J. J., Fantegrossi, W. E., & Newton, T. F. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0601-2 · Cited by 137 · see citing works
Factor Analysis of Computerized and Traditional Tests Used in Mild Brain Injury Research
Bleiberg, J., Kane, R. L., Reeves, D., Garmoe, W. S., & Halpern, E. L. (2000) · The Clinical Neuropsychologist · doi:10.1076/1385-4046(200008)14:3;1-p;ft287 · Cited by 134 · see citing works
How does bupropion work as a smoking cessation aid?
Warner, C., & Shoaib, M. (2005) · Addiction Biology · doi:10.1080/13556210500222670 · Cited by 115 · see citing works
Effect of bupropion on nicotine self-administration in rats
Rauhut, A. S., Neugebauer, N. M., Dwoskin, L. P., & Bardo, M. T. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1450-x · Cited by 111 · see citing works
Acute doses of d-amphetamine and bupropion increase cigarette smoking
Cousins, M. S., Stamat, H. M., & de Wit, H. (2001) · Psychopharmacology · doi:10.1007/s002130100802 · Cited by 111 · see citing works
Rush, C. R., Kollins, S. H., & Pazzaglia, P. J. (1998) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.6.1.32 · Cited by 108 · see citing works
Pesola, G. R., & Avasarala, J. R. (2002) · Journal of Emergency Medicine · doi:10.1016/s0736-4679(01)00474-7 · Cited by 104 · see citing works
Glick, S. D., Maisonneuve, I. M., & Kitchen, B. A. (2002) · European Journal of Pharmacology · doi:10.1016/s0014-2999(02)01944-1 · Cited by 92 · see citing works
Developments in pharmacotherapy for tobacco dependence: past, present and future
Foulds, J., Steinberg, M. B., Williams, J. M., & Ziedonis, D. M. (2006) · Drug and Alcohol Review · doi:10.1080/09595230500459529 · Cited by 74 · see citing works
Clinical pharmacokinetics of bupropion: a review.
Lai, A. A., & Schroeder, D. H. (1983) · PubMed · Cited by 67 · see citing works
Neurochemical and Psychotropic Effects of Bupropion in Healthy Male Subjects
Gobbi, G., Slater, S., Boucher, N., Debonnel, G., & Blier, P. (2003) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000084023.22282.03 · Cited by 56 · see citing works
de la Garza, R., & Johanson, C. E. (1987) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39316-x · Cited by 55 · see citing works
Kamien, J. B., & Woolverton, W. L. (1989) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)24169-6 · Cited by 54 · see citing works
Saunders, J. B. (2004) · Cited by 52 · see citing works
Nicotine and Non-nicotine Smoking Cessation Pharmacotherapies
Frishman, W. H., Mitta, W., Kupersmith, A., & Ky, T. (2006) · Cardiology in Review · doi:10.1097/01.crd.0000172309.06270.25 · Cited by 49 · see citing works
Dopaminergic mediation of the discriminative stimulus effects of bupropion in rats
Terry, P., & Katz, J. L. (1997) · Psychopharmacology · doi:10.1007/s002130050443 · Cited by 43 · see citing works
CYP2B6 is expressed in African Green monkey brain and is induced by chronic nicotine treatment
Lee, A. M., Miksys, S. L., Palmour, R. M., & Tyndale, R. F. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.10.003 · Cited by 42 · see citing works
Teneggi, V., Tiffany, S. T., Squassante, L., Milleri, S., Ziviani, L., & Bye, A. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0145-x · Cited by 39 · see citing works
Perceptual changes with bupropion, a novel antidepressant
Becker, R. E., & Dufresne, R. L. (1982) · American Journal of Psychiatry · doi:10.1176/ajp.139.9.1200 · Cited by 39 · see citing works
Rauhut, A. S., Dwoskin, L. P., & Bardo, M. T. (2005) · Nicotine & Tobacco Research · doi:10.1080/14622200500381384 · Cited by 32 · see citing works
Sabol, K. E., Richards, J. B., Broom, S. L., Roach, J. T., & Hausknecht, K. A. (2003) · Behavioural Pharmacology · doi:10.1097/00008877-200311000-00001 · Cited by 24 · see citing works
Bupropion sustained release. A therapeutic review of Zyban.
Zwar, N. A., & RICHMOND, R. L. (2002) · PubMed · Cited by 21 · see citing works
The impact of bupropion on psychomotor performance.
Paul, M. A., Gray, G. W., Kenny, G., et al. (2002) · PubMed · Cited by 15 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- Derogatis L. SCL-90-R Manual-II. Townson, MD: Clinical Psychometric Research; 1983. [Google Scholar]
- Logan GD. Attention, automaticity, and the ability to stop a speeded choice response. In: Long J, Baddeley AD, editors. Attention and Performance IX. Hillsdale, NJ: Lawerence Erlbaum; 1981. [Google Scholar]
- Mazur JE. An adjusting amount procedure for studying delayed reinforcement. In: Commons JEMML, Nevin JA, Rachlin H, editors. Quantitative Analysis of Behavior: The Effects of Delay and of Intervening Events on Reinforcement Value. Vol. 5. Hillsdale: Lawrence Erlbaum Associates; 1987. pp. 55–73. [Google Scholar]
- McNair DM, Lorr M, Droppleman LF. Manual for the profile of mood states: Educational and Industrial Testing Service 1971 [Google Scholar]
Cited by
Sorted by citations
Inhibition and impulsivity: behavioral and neural basis of response control
Bari, A., & Robbins, T. W. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.06.005 · Cited by 1,921 · see citing works
Impulsivity as a determinant and consequence of drug use: a review of underlying processes
de Wit, H. (2009) · Addiction Biology · doi:10.1111/j.1369-1600.2008.00129.x · Cited by 1,415 · see citing works
Dopamine, serotonin and impulsivity
Dalley, J. W., & Roiser, J. P. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.03.065 · Cited by 501 · see citing works
Paying attention to attention in depression
Keller, A. S., Leikauf, J. E., Holt-Gosselin, B., Staveland, B. R., & Williams, L. M. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0616-1 · Cited by 329 · see citing works
Dissecting impulsivity and its relationships to drug addictions
Jentsch, J. D., Ashenhurst, J. R., Cervantes, M. C., Groman, S. M., James, A. S., & Pennington, Z. T. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12388 · Cited by 281 · see citing works
Dopamine, Time, and Impulsivity in Humans
Pine, A., Shiner, T., Seymour, B., & Dolan, R. J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6028-09.2010 · Cited by 300 · see citing works
Paloyelis, Y., Asherson, P., Mehta, M. A., Faraone, S. V., & Kuntsi, J. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.124 · Cited by 180 · see citing works
Linking ADHD to the Neural Circuitry of Attention
Mueller, A., Hong, D. S., Shepard, S., & Moore, T. (2017) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2017.03.009 · Cited by 158 · see citing works
Spencer, S. V., Hawk, L. W., Richards, J. B., Shiels, K., Pelham, W. E., & Waxmonsky, J. G. (2009) · Journal of Abnormal Child Psychology · doi:10.1007/s10802-009-9316-2 · Cited by 93 · see citing works
The impact of alcohol and energy drink consumption on intoxication and risk-taking behavior
Peacock, A., Bruno, R., Martin, F. H., & Carr, A. (2013) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.12086 · Cited by 78 · see citing works
Petry, N. M. (2012) · Journal of Abnormal Psychology · doi:10.1037/a0024782 · Cited by 67 · see citing works
The dopamine augmenter L-DOPA does not affect positive mood in healthy human volunteers.
Liggins, J., Pihl, R. O., Benkelfat, C., & Leyton, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0028370 · Cited by 58 · see citing works
- Authors
- Acheson, A., & de Wit, H.
- Affiliations
- The University of Texas at San Antonio Health Science Center (US)
- Venue
- Experimental and Clinical Psychopharmacology
- Published
- 2008-04
- Volume
- 16
- Issue
- 2
- Pages
- 113-123
- ISSN
- 1064-1297 (ISSN-L)
- 1936-2293
- PMC
- PMC4270475
- OpenAlex
- W2072489212
- Cited by
- 82
- References
- 67
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 5 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 5 · 2016: 5 · 2015: 7 · 2014: 5 · 2013: 8 · 2012: 5
- FWCI
- 4.45
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Experimental and Clinical Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Sponsor name not included (DA09133; T32DA07255)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- bupropion, attention, impulsivity, impulse control, smoking cessation, d-amphetamine, reaction time, stop-signal task, delay discounting, probability discounting, Balloon Analogue Risk Task, risk-taking, arousal, mood, healthy young adults
- MeSH terms
- Adolescent, Adult, Affect, Attention, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Impulsive Behavior, Indoles, Male, Middle Aged, Surveys and Questionnaires, Smoking, Smoking Cessation, Bupropion, Dopamine Uptake Inhibitors
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