Randomized clinical trial of cognitive behavioral therapy (CBT) versus acceptance and commitment therapy (ACT) for mixed anxiety disorders

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Items 101–187 of 187

1. Predictors of recovery from post-deployment posttraumatic stress disorder symptoms in war veterans: the contributions of psychological flexibility, mindfulness, and self-compassion
   Meyer, Eric C., Szabo, Yvette Z., Frankfurt, Sheila B., Kimbrel, Nathan A., DeBeer, Bryann B., Morissette, Sandra B. · 2019 · Behaviour Research and Therapy
2. Case study: A novel application of mindfulness- and acceptance-based components to treat misophonia
   Schneider, Rebecca L., Arch, Joanna J. · 2017 · Journal of Contextual Behavioral Science
3. Through the extended evolutionary meta-model, and what ACT found there: ACT as a process-based therapy
   Ong, Clarissa W., Ciarrochi, Joseph, Hofmann, Stefan G., Karekla, Maria, Hayes, Steven C. · 2024 · Journal of Contextual Behavioral Science
4. The credibility of exposure therapy: Does the theoretical rationale matter?
   Arch, Joanna J., Twohig, Michael P., Deacon, Brett J., Landy, Lauren N., Bluett, Ellen J. · 2015 · Behaviour Research and Therapy
5. Mindfulness and acceptance-based behavioral therapies for anxiety disorders.
   Roemer, Lizabeth, Williston, Sarah K., Eustis, Elizabeth H., Orsillo, Susan M. · 2013 · Current Psychiatry Reports
6. Association between obsessive-compulsive and related disorders and experiential avoidance: A systematic review and meta-analysis
   Angelakis, Ioannis, Pseftogianni, Foteini · 2021 · Journal of Psychiatric Research
7. Blended Acceptance and Commitment Therapy Versus Face-to-face Cognitive Behavioral Therapy for Older Adults With Anxiety Symptoms in Primary Care: Pragmatic Single-blind Cluster Randomized Trial.
   Witlox, Maartje, Garnefski, Nadia, Kraaij, Vivian, de Waal, Margot W M, Smit, Filip, Bohlmeijer, Ernst, Spinhoven, Philip · 2021 · Journal of Medical Internet Research
8. Changes of valued behaviors and functioning during an Acceptance and Commitment Therapy Intervention
   Wersebe, Hanna, Lieb, Roselind, Meyer, Andrea H., Hoyer, Jürgen, Wittchen, Hans-Ulrich, Gloster, Andrew T. · 2017 · Journal of Contextual Behavioral Science
9. Acceptance-and mindfulness-based interventions for health behavior change: Systematic reviews and meta-analyses
   Roche, Anne I., Kroska, Emily B., Denburg, Natalie L. · 2019 · Journal of Contextual Behavioral Science
10. Acceptance and commitment group therapy for health anxiety - Results from a pilot study
    Eilenberg, T., Kronstrand, L., Fink, P., Frostholm, L. · 2013 · Journal of Anxiety Disorders
11. Effectiveness of a Transdiagnostic guided internet-delivered protocol for emotional disorders versus treatment as usual in specialized care: randomized controlled trial
    González-Robles, Alberto, Díaz-García, Amanda, García-Palacios, Azucena, Roca, Pablo, Ramos-Quiroga, Josep Antoni, Botella, Cristina · 2020 · Journal of Medical Internet Research
12. Acceptance and commitment therapy compared to treatment as usual in psychosis: A systematic review and meta-analysis
    Tonarelli, Silvina B, Pasillas, Rebecca · 2016 · Journal of psychiatry
13. Reductions in transdiagnostic factors as the potential mechanisms of change in treatment outcomes in the Unified Protocol: A randomized clinical trial
    Khakpoor, Sahel, Mohammadi Bytamar, Jahangir, Saed, Omid · 2019 · Research in Psychotherapy: Psychopathology, Process and Outcome
14. Acceptance and commitment therapy for the treatment of anxiety disorders: A concise review
    Landy, Lauren N, Schneider, Rebecca L, Arch, Joanna J · 2015 · Current Opinion in Psychology
15. The Idionomic Future of Cognitive Behavioral Therapy: What Stands Out From Criticisms of ACT Development
    Hayes, Steven C., Hofmann, Stefan G., Ciarrochi, Joseph · 2023 · Behavior Therapy
16. Randomized controlled trial of acceptance and commitment therapy versus traditional cognitive behavior therapy for social anxiety disorder: Symptomatic and behavioral outcomes
    Herbert, James D., Forman, Evan M., Kaye, Joanna L., Gershkovich, Marina, Goetter, Elizabeth, Yuen, Erica K., Glassman, Lisa, Goldstein, Stephanie, Hitchcock, Peter, Tronieri, Jena Shaw et al. · 2018 · Journal of Contextual Behavioral Science
17. Mechanisms of the acceptance and commitment therapy: A meta-analytic structural equation model
    REN, Zhihong, ZHAO, Chunxiao, BIAN, Cheng, ZHU, Wenzhen, JIANG, Guangrong, ZHU, Zhuohong · 2019 · Acta Psychologica Sinica
18. The importance of theory in cognitive behavior therapy: A perspective of contextual behavioral science
    Herbert, James D., Gaudiano, Brandon A., Forman, Evan M. · 2013 · Behavior Therapy
19. Relative effectiveness of mindfulness and cognitive behavioral interventions for anxiety disorders: Meta-analytic review
    Singh, Samina K., Gorey, Kevin M. · 2018 · Social Work in Mental Health
20. The differences between acceptance and commitment therapy (ACT) and cognitive behavioral therapy: A three-level meta-analysis
    Fang, Shuanghu, Ding, Dongyan · 2023 · Journal of Contextual Behavioral Science
21. Experiential avoidance as a mediator of the association between posttraumatic stress disorder symptoms and social support: A longitudinal analysis
    Kelly, Megan M., DeBeer, Bryann B., Meyer, Eric C., Kimbrel, Nathan A., Gulliver, Suzy B., Morissette, Sandra B. · 2019 · Psychological Trauma Theory Research Practice and Policy
22. Group acceptance and commitment therapy (ACT) for bipolar disorder and co-existing anxiety–an open pilot study
    Pankowski, Sara, Adler, Mats, Andersson, Gerhard, Lindefors, Nils, Svanborg, Cecilia · 2017 · Cognitive Behaviour Therapy
23. Changes in threat-related cognitions and experiential avoidance in group-based transdiagnostic CBT for anxiety disorders
    Espejo, Emmanuel P., Gorlick, Amanda, Castriotta, Natalie · 2017 · Journal of Anxiety Disorders
24. The Phenomenon of Treatment Dropout, Reasons and Moderators in Acceptance and Commitment Therapy and Other Active Treatments: A Meta-Analytic Review
    Karekla, Maria, Constantinou, Penelopi, Ioannou, Myria, Gloster, Andrew T., Kareklas, Ioannis · 2019 · Clinical Psychology in Europe
25. Public speaking avoidance as a treatment moderator for social anxiety disorder.
    Mesri, Bita, Niles, Andrea N., Pittig, Andre, LeBeau, Richard T., Haik, Ethan, Craske, Michelle G. · 2017 · Journal of Behavior Therapy and Experimental Psychiatry
26. Applying a novel statistical method to advance the personalized treatment of anxiety disorders: A composite moderator of comparative drop-out from CBT and ACT
    Niles, Andrea N., Wolitzky-Taylor, Kate B., Arch, Joanna J., Craske, Michelle G. · 2017 · Behaviour Research and Therapy
27. Evaluating the Effectiveness of ACT for Anxiety Disorders in a Self-Help Context: Outcomes From a Randomized Wait-List Controlled Trial.
    Ritzert, Timothy R., Forsyth, John P., Sheppard, Sean C., Boswell, James F., Berghoff, Christopher R., Eifert, Georg H. · 2016 · Behavior Therapy
28. An Examination of the Factor Structure of the Multidimensional Psychological Flexibility Inventory.
    Thomas, Kelsey N., Bardeen, Joseph R., Witte, Tracy K., Rogers, Travis A., Benfer, Natasha, Clauss, Kate · 2022 · Assessment
29. Pilot Program Combining Acceptance and Commitment Therapy with Stuttering Modification Therapy for Adults who Stutter: A Case Report.
    Freud, Debora, Levy-Kardash, Omer, Glick, Ittai, Ezrati-Vinacour, Ruth · 2020 · Folia Phoniatrica et Logopaedica
30. An Integrated, Acceptance-Based Behavioral Approach for Depression With Social Anxiety: Preliminary Results
    Dalrymple, Kristy L., Morgan, Theresa A., Lipschitz, Jessica M., Martinez, Jennifer H., Tepe, Elizabeth, Zimmerman, Mark · 2014 · Behavior Modification
31. Positive and negative affect change following psychotherapeutic treatment for anxiety-related disorders: A systematic review and meta-analysis
    Hoffman, Samantha N., Rassaby, Madeleine M., Stein, Murray B., Taylor, Charles T. · 2024 · Journal of Affective Disorders
32. Effect of Acceptance and Commitment Therapy (ACT) on Anxiety and Quality of Life During Pregnancy: A Mental Health Clinical Trial Study
    Vakilian, Katayon, Zarei, Fahimeh, Majidi, Abed · 2019 · Iranian Red Crescent Medical Journal
33. Cognitive defusion for reducing distressing thoughts in adults with autism
    Maisel, Max E., Stephenson, Kevin G., Cox, Jonathan C., South, Mikle · 2019 · Research in Autism Spectrum Disorders
34. Implementation of a Guided, Digital Cognitive Behavioral Program for Anxiety in Primary Care: Preliminary Findings of Engagement and Effectiveness
    Yu, Jessica S., Szigethy, Eva, Wallace, Meredith, Solano, Francis, Oser, Megan · 2018 · Telemedicine and e-Health
35. A Randomized Trial of Acceptance and Commitment Therapy and Traditional Cognitive-Behavioral Therapy Self-Help Books for Social Anxiety
    Krafft, Jennifer, Twohig, Michael P., Levin, Michael E. · 2020 · Cognitive Therapy and Research
36. A systematic review and meta-analysis of mindfulness-and acceptance-based interventions for affect intolerance/sensitivity
    Kraemer, Kristen M., Luberto, Christina M., Hall, Daniel L., Ngo, Long H., Yeh, Gloria Y. · 2020 · Behaviour Research and Therapy
37. WHAT MINDFULNESS BRINGS TO PSYCHOTHERAPY FOR ANXIETY AND DEPRESSION: The Cutting Edge: Mindfulness for Anxiety and Depression
    Lang, Ariel J. · 2013 · Depression and Anxiety
38. A randomized controlled trial of a group acceptance-based intervention for cancer survivors experiencing anxiety at re-entry ('Valued Living'): Study protocol
    Arch, Joanna J., Mitchell, Jill L., Genung, Sarah R., Fisher, Robert, Andorsky, David J., Stanton, Annette L. · 2019 · BMC Cancer
39. Guided Internet-Based Self-Help Intervention for Social Anxiety Disorder With Videoconferenced Therapist Support
    Gershkovich, Marina, Herbert, James D., Forman, Evan M., Glassman, Lisa · 2016 · Cognitive and Behavioral Practice
40. Low baseline pCO2 predicts poorer outcome from behavioral treatment: Evidence from a mixed anxiety disorders sample
    Davies, Carolyn D., Craske, Michelle G. · 2014 · Psychiatry Research
41. A Comparison of Two Brief Interventions for Obsessional Thoughts: Exposure and Acceptance.
    Fabricant, Laura E., Abramowitz, Jonathan S., Dehlin, John P., Twohig, Michael P. · 2013 · Journal of Cognitive Psychotherapy
42. Chinese adolescents' mindfulness and internalizing symptoms: The mediating role of rumination and acceptance.
    Yu, Meng, Zhou, Huiwei, Xu, Hanghang, Zhou, Hui · 2021 · Journal of Affective Disorders
43. A systematic review of inclusion of minoritized populations in randomized controlled trials of acceptance and commitment therapy
    Misra, Akshay, Bryan, Ashley, S. Faber, Naomi, Printz Pereira, Destiny, Faber, Sonya, T. Williams, Monnica, D. Skinta, Matthew · 2023 · Journal of Contextual Behavioral Science
44. The relationship between low levels of mindfulness skills and pathological worry: The mediating role of psychological inflexibility. [La relación entre habilidades de mindfulness y preocupación patológica: El rol mediador de la inflexibilidad psicológica]
    Ruiz, Francisco J. · 2014 · Anales de Psicologia
45. A pilot randomized controlled trial of culturally-adapted, telehealth group acceptance and commitment therapy for iranian adolescent females reporting symptoms of anxiety
    Zemestani, Mehdi, Hosseini, Mojgan, Petersen, Julie M., Twohig, Michael P. · 2022 · Journal of Contextual Behavioral Science
46. Acceptance and Commitment Therapy for Health Anxiety
    Hoffmann, Ditte, Rask, Charlotte U., Frostholm, Lisbeth · 2019 · The Clinician's Guide to Treating Health Anxiety
47. In-person and online-delivered acceptance and commitment therapy for hoarding disorder: a multiple baseline study
    Ong, Clarissa W., Krafft, Jennifer, Panoussi, Franchessca, Petersen, Julie M., Levin, Michael E., Twohig, Michael P. · 2021 · Journal of Contextual Behavioral Science
48. Does the theoretical perspective of exposure framing matter? Acceptance, fear reduction/cognitive reappraisal, and values-framing of exposure for social anxiety
    Bluett, Ellen J., Landy, Lauren L., Twohig, Michel P., Arch, Joanna J. · 2016 · Journal of Cognitive Psychotherapy
49. Trajectories of change in well-being during cognitive behavioral therapies for anxiety disorders: Quantifying the impact and covariation with improvements in anxiety
    Gallagher, Matthew W., Phillips, Colleen A., D'Souza, Johann, Richardson, Angela, Long, Laura J., Boswell, James F., Farchione, Todd J., Barlow, David H. · 2020 · Psychotherapy
50. NeuroCARE: A Randomized Controlled Trial of a Psychological Intervention for Caregivers of Patients With Primary Malignant Brain Tumors
    Forst, Deborah A., Podgurski, Alyx F., Strander, Sumita M., Whitman, Jessica D., Datta, Shibani, Pintro, Kedie, Horick, Nora K., Willis, Kelcie D., Sannes, Timothy S., Greer, Joseph A. et al. · 2024 · Journal of Clinical Oncology
51. Factor structure and measurement invariance of the Multidimensional Psychological Flexibility Inventory (MPFI) in Chinese samples
    Fang, Shuanghu, Huang, Mingjie, Ding, Dongyan · 2024 · Current Psychology
52. Evaluating ACT Processes in Relation to Outcome in Self-Help Treatment for Anxiety-Related Problems.
    Ritzert, Timothy R., Berghoff, Christopher R., Tifft, Eric D., Forsyth, John P. · 2020 · Behavior Modification
53. Narcissism and Quality of Life: The Mediating Role of Relationship Patterns
    Ellison, William D., Acuff, M. Chase, Kealy, David, Joyce, Anthony S., Ogrodniczuk, John S. · 2020 · Journal of Nervous & Mental Disease
54. Acceptance and Commitment Therapy for Depression and Anxiety
    Annunziata, A.J., Green, J.D., Marx, B.P. · 2016 · Encyclopedia of Mental Health
55. Differential Effects of Word-Repetition Rate on Cognitive Defusion of Believability and Discomfort of Negative Self-Referential Thoughts Postintervention and at One-Month Follow-Up
    Tyndall, Ian, Papworth, Richard, Roche, Bryan, Bennett, Marc · 2017 · The Psychological Record
56. Case Study of Acceptance and Commitment Therapy and Functional Analysis for Emetophobia
    Bogusch, Leah M., Moeller, Mary T., O’Brien, William H. · 2018 · Clinical Case Studies
57. A Review of Research on Acceptance and Commitment Therapy for Anxiety and Obsessive-Compulsive and Related Disorders
    Twohig, Michael P., Capel, Leila K., Levin, Michael E. · 2024 · Psychiatric Clinics of North America
58. Treatment of Agoraphobia in a Pregnant Woman: A Combination of Exposure and Acceptance and Commitment Therapy
    Cullinan, Colleen C., Gaynor, Scott T. · 2015 · Clinical Case Studies
59. Mindfulness and acceptance-based behavioral therapies
    Roemer, Lizabeth, Graham, Jessica R., Morgan, Lucas, Orsillo, Susan M. · 2014 · The Wiley Handbook of Anxiety Disorders
60. Development and initial validation of a brief questionnaire on the patients' view of the in-session realization of the six core components of Acceptance and Commitment Therapy
    Probst, Thomas, Mühlberger, Andreas, Kühner, Johannes, Eifert, Georg H., Pieh, Christoph, Hackbarth, Timo, Mander, Johannes · 2020 · Clinical Psychology in Europe
61. One-day acceptance and commitment therapy (ACT) workshop improves anxiety but not vascular function or inflammation in adults with moderate to high anxiety levels in a randomized controlled trial.
    Fiedorowicz, Jess G., Dindo, Lilian, Ajibewa, Tiwaloluwa, Persons, Jane, Marchman, James, Holwerda, Seth W., Abosi, Oluchi J., DuBose, Lyndsey E., Wooldridge, Nealy, Myers, Janie et al. · 2021 · General Hospital Psychiatry
62. Comparing paths to quality of life: Contributions of ACT and cognitive therapy intervention targets in two highly anxious samples
    Berghoff, Christopher R., Forsyth, John P., Ritzert, Timothy R., Sheppard, Sean C. · 2014 · Journal of Contextual Behavioral Science
63. Group acceptance and commitment therapy for adolescent anxiety: A systematic review and meta-analysis
    Burley, Jade, McAloon, John · 2024 · Journal of Contextual Behavioral Science
64. Acceptance and mindfulness-based therapies for social anxiety disorder: Current findings and future directions
    Herbert, James D., Gershkovich, Marina, Forman, Evan M. · 2014 · The Wiley Blackwell Handbook of Social Anxiety Disorder
65. The effectiveness of group psychotherapy based on acceptance and commitment on increasing of mental health and the quality of women's life with breast cancer
    Esmali, Ahmad, Alizadeh, Masoomeh · 2015 · Biosciences Biotechnology Research Asia
66. Effectiveness of ACT-based intervention in compliance with the model for sustainable mental health: A cluster randomized control trial in a group of older adults
    Chojak, Agnieszka · 2023 · Journal of Contextual Behavioral Science
67. Comparison of the effectiveness of cognitive-behavioral therapy and acceptance and commitment therapy on cognitive distortions and rumination in adolescents with social anxiety disorder
    Ebrahimi, Shirin, Moheb, Naiemeh, Alivani Vafa, Marziyeh · 2024 · Practice in Clinical Psychology
68. Roles of Parental Psychological Flexibility, Self-Compassion, and Self-Efficacy in Affecting Mental Health and Quality of Life in Parents of Children with Eczema
    Chong, Yuen Yu, Kwan, Joycelyn Yee Man, Yau, Pui Tik, Cheng, Ho Yu, Chien, Wai Tong · 2023 · Healthcare
69. Liens entre le développement de la pleine conscience et l’amélioration de la dépression et de l’anxiété
    Bouvet, Cyrille, Grignon, Clémence, Zachariou, Zacharias, Lascar, Philippe · 2015 · Annales Médico-psychologiques revue psychiatrique
70. The Effectiveness of Acceptance-Commitment Therapy on Anxiety and Depression among Patients on Methadone Treatment: A Pilot Study
    Saedy, Mozhgan, Kooshki, Shirin, Jamali Firouzabadi, Mahmoud, Emamipur, Suzan, Rezaei Ardani, Amir · 2015 · Iranian Journal of Psychiatry and Behavioral Sciences
71. A randomized controlled trial for symptoms of anxiety and depression: Effects of a 1 -day acceptance and commitment training workshop
    Dindo, Lilian, Fiedorowicz, Jess G., Boykin, Derrecka M., Wooldridge, Nealy, Myers, Janie, Ajibewa, Tiwaloluwa, Stroud, Amy, Kuwaye, Daren, Liu, Zhuangzhuang, Pierce, Gary L · 2021 · Annals of Clinical Psychiatry
72. Do Unified Protocol modules exert general or unique effects on anxiety, depression, and transdiagnostic targets?
    Southward, Matthew W., Lane, Sean P., Shroyer, Sara E., Sauer-Zavala, Shannon · 2023 · Journal of Mood & Anxiety Disorders
73. Building Psychological Flexibility to Mitigate Adjustment Disorder: Assessing Treatment Progress With a Measure of Treatment Processes
    Wiggs, Kristin A., Drake, Chad E. · 2016 · Clinical Case Studies
74. Acceptance and Commitment Therapy for OCD
    Smith, Brooke M., Bluett, Ellen J., Lee, Eric B., Twohig, Michael P. · 2017 · The Wiley Handbook of Obsessive Compulsive Disorders
75. Acceptance-based behavioral therapies for generalized anxiety disorder (GAD)
    Roemer, Lizabeth, Orsillo, Susan M. · 2020 · Generalized Anxiety Disorder and Worrying
76. Acceptance and Commitment Therapy (ACT)
    Forman, Evan M., Juarascio, Adrienne S., Martin, Lindsay M., Herbert, James D. · 2015 · The Encyclopedia of Clinical Psychology
77. Acceptance and commitment therapy for older people with treatment-resistant generalised anxiety disorder: The FACTOID feasibility study
    Gould, Rebecca L, Wetherell, Julie Loebach, Serfaty, Marc A, Kimona, Kate, Lawrence, Vanessa, Jones, Rebecca, Livingston, Gill, Wilkinson, Philip, Walters, Kate, Novere, Marie Le et al. · 2021 · Health Technology Assessment
78. Nonresponder does not mean not better: Improvement in nonsymptom domains in complex depressed patients who are not symptomatic responders to intensive treatment
    Zimmerman, Mark, Lin, Sin-Ying · 2023 · Psychiatry Research
79. A functional and cohesive treatment of Tourette's disorder and chewing tobacco use
    Morrison, Kate L., Twohig, Michael P. · 2016 · Clinical Case Studies
80. Which emotion regulation strategies are mediating the outcome of acceptance and commitment therapy compared to cognitive-behaviour therapy in the treatment of anxiety symptoms?
    Spinhoven, Philip, Kraaij, Vivian, Garnefski, Nadia, Bohlmeijer, Ernst, Witlox, Maartje · 2026 · Psychotherapy Research
81. Internet‐Based Acceptance and Commitment Therapy With Interoceptive Exposure for Panic Disorder: A Randomized Controlled Trial and Working Alliance Analysis.
    Bäckman, Lisa, Weineland, Sandra, Vernmark, Kristofer, Radvogin, Ella, Bjälkebring, Pär, Enbuske, Esther, Hermansson, Ida, Johansson, Nina, Petersen, Nathalie, Hursti, Timo · 2026 · Scandinavian Journal of Psychology
82. The Efficacy of Acceptance and Commitment Therapy for Reducing Anxiety in Parents of Children With Special Needs: A Meta-Analysis.
    Qin, Zhikai, Lan, Jiajun, He, Haoran, Jun, Yin · 2026 · Research on Child and Adolescent Psychopathology
83. Anxiety and Fear-Related Disorders: Generalized Anxiety Disorder
    Rosellini, Anthony J., Brown, Timothy A. · 2024 · Tasman’s Psychiatry
84. Investigating an Acceptance and Commitment Therapy-Based Exposure Therapy Intervention in Treatment-Refractory OCD and Related Disorders: Changes in Psychological Flexibility, Treatment Engagement, and Treatment Perceptions.
    Gruner, Nate G., Cullen, Jenifer M., Crosby, Jesse M., DeCross, Stephanie N., Mathes, Brittany, Garner, Lauryn, Gironda, Christina, Hu, Yuanjun, Krompinger, Jason W., Elias, Jason A. et al. · 2024 · Journal of Cognitive Psychotherapy
85. Incremental Validity of Cognitive-Behavioral Therapy and Acceptance and Commitment Therapy Mechanisms for Anxiety and Panic Symptomology.
    Broman-Fulks, Joshua J., Bergquist, John J., Hall, Christian A., Thomas, Kelsey, Kelso, Kerry C. · 2023 · Journal of Cognitive Psychotherapy
86. Acceptance and commitment therapy in the treatment of anxiety disorders in relation to classical cognitive-behavioural therapy
    Instytut Psychologii, Wydział Filozoficzny, Uniwersytet Jagielloński, Kraków, Polska, Legierski, Jacek · 2018 · Psychiatria i Psychologia Kliniczna
87. Acceptance and commitment therapy for psychosomatic outcomes and quality of life in adults with cancer: Systematic review and meta-analysis.
    Kang, Zhixuan, Xu, Yijia, Li, Huiyuan, Arbing, Rachel, Chen, Wei-Ti, Ke, Xi, Huang, Feifei · 2026 · European Journal of Oncology Nursing