The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index; none of the 61 sources its claims cite is checked for support yet.
The hippocampus: a manifesto for change
Open accessAbstract
We currently lack a unified and mechanistic account of how the hippocampus supports a range of disparate cognitive functions that includes episodic memory, imagining the future, and spatial navigation. Here, we argue that in order to leverage this long-standing issue, traditional notions regarding the architecture of memory should be eschewed. Instead, we invoke the idea that scenes are central to hippocampal information processing. This view is motivated by mounting evidence that the hippocampus is constantly constructing spatially coherent scenes, automatically anticipating and synthesizing representations of the world beyond the immediate sensorium. By characterizing the precise relationship between scenes and the hippocampus, we believe a theoretically enriched understanding of its fundamental role and its breakdown in pathology can emerge.
Overview
AI snapshot
Written from the paper’s full text.
TL;DR
Maguire argues that the hippocampus is not primarily an episodic memory device but instead automatically constructs spatially coherent scenes, a view termed scene construction theory (SCT). This framework is proposed to unify episodic memory, future imagining, spatial navigation, and related functions, with boundary extension and fMRI evidence cited as key support.
Key findings
- SCT posits that scenes are the “primary currency” of the hippocampus: it constructs atemporal, spatially coherent scenes that provide the backdrop for episodic memories, imagined future experiences, spatial navigation, and perhaps mind wandering and dreaming.
- In Mullally, Intraub, and Maguire (2012), seven patients with selective bilateral hippocampal damage and amnesia showed more veridical memory and significantly fewer boundary-extension errors than controls across three independent measures; in the haptic task, patients’ reconstructed scene areas did not differ significantly from studied scenes, whereas controls’ reconstructed scenes were significantly larger.
- In a scene probe task, these patients could recount expected beyond-view details conceptually but produced significantly fewer spatial details than controls and typically reported being unable to visualize the extended scene in their mind’s eye.
- Chadwick, Mullally, and Maguire (in press) found that boundary extension in healthy controls was associated with hippocampus and parahippocampal cortex engagement, with the hippocampus exerting top-down influence on PHC and early visual cortex; patient P01, densely amnesic but with preserved scene construction, engaged remnant right hippocampus during scene construction.
Methods
- Theoretical manifesto/review, not an empirical study; the authors synthesize neuropsychological and neuroimaging findings to propose SCT and compare it with alternative accounts such as relational memory, constructive episodic simulation, and cognitive map/boundary vector cell models.
- Evidence discussed includes prior studies of patients with bilateral hippocampal lesions/amnesia, including seven patients in Mullally et al. (2012) and patient P01, plus fMRI studies in healthy participants and P01.
- Main analysis is conceptual: the paper argues that scene construction, rather than memory or time, is the common hippocampal process underlying disparate functions.
Limitations
- The authors state their proposal is “not bulletproof” and requires a good deal more investigation; the piece is not intended as a forensic comparison of hippocampal theories or an exhaustive literature review.
- The authors state further work is needed to elucidate boundary extension in patients with lesions outside the hippocampus, to uncover exactly how the hippocampus facilitates scene construction, to examine its relationship with pattern separation and pattern completion, and to definitively establish that an inability to construct scenes explains the full constellation of deficits from hippocampal pathology.
- The text makes evident that no new primary data are reported and that some proposals are speculative, such as the suggestion that verbal memory tasks may benefit from scene-based imagery strategies; SCT could be falsified by a patient with impaired scene construction and preserved episodic memory, which has not yet been identified.
Model-written summary. Check it against the paper before relying on it.
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Claims the paper makes
43 Not checked yet · 31 Own interpretation · 1 No basis given
In the paper
“Seven patients with selective bilateral hippocampal damage and amnesia correctly identified that the study and test pictures were identical with greater frequency than controls, demonstrating more veridical memory (see Figure 4b).”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
What the sources say
- Not checked yetcites Mullally, Intraub, & Maguire, 2012
boostedcorrelationaln = 7- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The SCT posits that the hippocampus facilitates the construction of atemporal scenes allowing the event details of episodic memories and imagined future experiences to be martialed, bound and played out in a coherent spatial context.”
§ The Hippocampus: A Manifesto for Change > Episodic Memory and Imagination
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The first (the BE effect) requires intact scene construction because it involves the active extrapolation of the scene beyond its physical boundaries resulting in an internally generated “extended scene” representation, which persists when the scene is no longer visible.”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“In both instances, the amnesic patients’ BE was greatly attenuated.”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
What the sources say
- Not checked yetcites Mullally, Intraub, & Maguire, 2012
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“SCT proposes that despite the differences between them, these functions each require a crucial ingredient that is supplied by the hippocampus, and that is the ability to internally construct spatially coherent scenes.”
§ The Hippocampus: A Manifesto for Change > Episodic Memory and Imagination
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“However, it does not account for why patients with hippocampal amnesia cannot construct spatially coherent atemporal fictitious scenes (see Figure 1), a task that is not future oriented or personally relevant (Hassabis, Kumaran, Vann, & Maguire, 2007; Mullally, Intraub, & Maguire, 2012).”
§ The Hippocampus: A Manifesto for Change > Episodic Memory and Imagination
What the sources say
- Not checked yetcites Hassabis, Kumaran, Vann, & Maguire, 2007
- Not checked yetcites Mullally, Intraub, & Maguire, 2012
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Indeed, a recent functional magnetic resonance imaging (fMRI) study revealed that frontal and parietal cortices, but not the hippocampus, supported mental time travel (Nyberg et al., 2010).”
§ The Hippocampus: A Manifesto for Change > Episodic Memory and Imagination
What the sources say
- Not checked yetcites Nyberg et al., 2010
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Overall, it seems that although the conscious awareness of time could be a core component of episodic memory, and the hippocampus might make use of temporal information when pertinent to the task at hand (MacDonald, Lepage, Eden, & Eichenbaum, 2011), the evidence suggests that for the hippocampus, it may not be primarily about time (Hassabis & Maguire, 2007).”
§ The Hippocampus: A Manifesto for Change > Episodic Memory and Imagination
What the sources say
- Not checked yetcites Hassabis & Maguire, 2007
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Overall, therefore, these hippocampal-damaged patients had significantly reduced BE relative to healthy-matched controls across three independent measures.”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
What the sources say
- Not checked yetcites Mullally, Intraub, & Maguire, 2012
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Importantly, the patients displayed greater confidence in their correct “the same” judgments than in their incorrect (BE-driven) closer-up responses (see Figure 4c).”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
What the sources say
- Not checked yetcites Mullally, Intraub, & Maguire, 2012
plainn = 7- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- It may state two separate claims as one. 17
- Probably not a substantial claim. 6
In the paper
“Although the margins for error here were large, the patients’ placement of the borders was so accurate that the area of their reconstructed scenes did not differ significantly from the area of the studied scenes. This was not the case for controls, whose reconstructed scenes were significantly larger than the studied scenes.”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
What the sources say
- Not checked yetcites Mullally, Intraub, & Maguire, 2012
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Andrews-Hanna, Reidler, Sepulcre, Poulin, and Buckner (2010) showed that imagining scenes actually accounted best for activity in the hippocampus and medial temporal lobes, whereas other regions were concerned with the self and time.”
§ The Hippocampus: A Manifesto for Change > Episodic Memory and Imagination
What the sources say
- Not checked yetcites Andrews-Hanna, Reidler, Sepulcre, Poulin, and Buckner, 2010
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“They also made significantly fewer BE-driven errors (“closer-up” responses), whereas the number of random errors (“farther away” responses) did not differ between the groups.”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
What the sources say
- Not checked yetcites Mullally, Intraub, & Maguire, 2012
plainn = 7- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“We know this because episodic memory subsumes multiple cognitive processes, some of which are not hippocampal dependent (Nyberg, Kim, Habib, Levine, & Tulving, 2010).”
§ The Hippocampus: A Manifesto for Change > Abstract
What the sources say
- Not checked yetcites Nyberg, Kim, Habib, Levine, & Tulving, 2010
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In this way, scene construction is held to underpin not only episodic memory and imagining the future but also cognitive functions such as spatial navigation (see Figure 2), and perhaps even mind wandering and dreaming.”
§ The Hippocampus: A Manifesto for Change > Episodic Memory and Imagination
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“The findings that hippocampal activity appears to be correlated with the number of boundaries imagined during fMRI (Bird, Capponi, King, Doeller, & Burgess, 2010) and place cell activity becomes less spatially specific when boundaries are removed (Barry et al., 2006) appear to bolster this argument.”
§ The Hippocampus: A Manifesto for Change > Scene Construction and the Cognitive Map Theory
What the sources say
- Not checked yetcites Bird, Capponi, King, Doeller, & Burgess, 2010
- Not checked yetcites Barry et al., 2006
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“This led to the cognitive map theory, which posits that a fundamental function of the hippocampus is the construction and maintenance of allocentric spatial maps of the environment (O’Keefe & Nadel, 1978).”
§ The Hippocampus: A Manifesto for Change > Scene Construction and the Cognitive Map Theory
What the sources say
- Not checked yetcites O’Keefe & Nadel, 1978
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The implication of this view is that the primary role of the hippocampus is not mnemonic.”
§ The Hippocampus: A Manifesto for Change > Current Exposition of the SCT
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
None of the sources cited for this claim have been checked yet.
In the paper
“Despite the rise and fall of imagery-based memory theories across the decades (Paivio, 1969), there is much evidence to suggest that visual imagery not only boosts paired-associate recall in healthy participants but also enabled patients with left temporal lobectomies to partially compensate for their verbal memory deficits (Jones, 1974).”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Verbal Memory
What the sources say
- Not checked yetcites Paivio, 1969
- Not checked yetcites Jones, 1974
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Chadwick, Mullally, and Maguire (in press) found that in healthy controls, the extrapolation of scenes (the BE effect) occurred rapidly around the time a scene was first viewed and was associated with engagement of the hippocampus and parahippocampal cortex (PHC; see Figure 6).”
§ The Hippocampus: A Manifesto for Change > Scene Construction and Boundary Extension
What the sources say
- Not checked yetcites Chadwick, Mullally, and Maguire, in press
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Rather, scene construction is viewed as an essential component of episodic memory without which episodic memories could not be truly and vividly expressed.”
§ The Hippocampus: A Manifesto for Change > The Hippocampus and Episodic Memory
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Instead, we suggest the hippocampus drives this automatic, anticipatory scene construction process, the product of which is fed back down the processing stream, enabling other areas to express the subjective experience of a seamless and continuous reality.”
§ The Hippocampus: A Manifesto for Change > Current Exposition of the SCT
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“As far as we are aware, this makes SCT unique, as no other theory of hippocampal function has scenes at its core.”
§ The Hippocampus: A Manifesto for Change > Current Exposition of the SCT
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“In this way, the hippocampus’ role in scene processing differs from the contributions of other so-called scene-selective brain regions like PHC, which is believed to represent the local visual scene (Epstein, 2008, 2011) or three-dimensional space (Mullally & Maguire, 2011; Zeidman, Mullally, Schwarzkopf, & Maguire, 2012), and retrosplenial cortex, which may play a specific role in representing”
§ The Hippocampus: A Manifesto for Change > Current Exposition of the SCT
What the sources say
- Not checked yetcites Epstein, 2008, 2011
- Not checked yetcites Mullally & Maguire, 2011
- Not checked yetcites Auger, Mullally, & Maguire, 2012
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“This finding accords with SCT in linking the hippocampus with scene construction but is at odds with the view of Squire et al. (2010), who argued that “for P01 future imagining was not hippocampal-dependent” (p. 19047; see also Maguire & Hassabis, 2011).”
§ The Hippocampus: A Manifesto for Change > The Hippocampus and Episodic Memory
What the sources say
- Not checked yetcites Squire et al. (2010)
- Not checked yetcites Maguire & Hassabis, 2011
plaincorrelationalSingle case- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“To summarize, although SCT does not preclude the existence of other mechanisms within the hippocampus, such as those that permit the binding of mnemonic details within a specific context (Ranganath, 2010), it maintains that for the hippocampus, scenes are special.”
§ The Hippocampus: A Manifesto for Change > Current Exposition of the SCT
What the sources say
- Not checked yetcites Ranganath, 2010
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Regardless, however, SCT does not permit the possibility that impaired scene construction could coexist with preserved episodic memory (the opposite pattern to that observed in P01) because within the SCT framework, scene construction and episodic memory are not considered to be independent processes.”
§ The Hippocampus: A Manifesto for Change > The Hippocampus and Episodic Memory
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“They may in fact be restricted to what is in front of their eyes, deprived of a level of subjective continuity, unable to visualize what is outside of their immediate view, what is behind them, or what is just around the corner.”
§ The Hippocampus: A Manifesto for Change > Current Exposition of the SCT
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
In the paper
“Although SCT argues that the hippocampus is primarily concerned with constructing scenes, and this underpins episodic memory by providing the spatial backdrop within which an episodic memory is played out, SCT explicitly recognizes that episodic memory requires additional processes on top of this scene construction process (Hassabis & Maguire, 2007, 2009).”
§ The Hippocampus: A Manifesto for Change > The Hippocampus and Episodic Memory
What the sources say
- Not checked yetcites Hassabis & Maguire, 2007, 2009
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In this way, the BVC model views boundaries as inward bounding (containing the space within specific boundaries), whereas SCT views boundaries (either physical boundaries such as walls or the edges of our current view) as outward looking, the point from which the hippocampus must extrapolate in order to make predictions about, and so imagine, the upcoming spatial environment.”
§ The Hippocampus: A Manifesto for Change > Scene Construction and the Cognitive Map Theory
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“For many of us, scenes are the language of thought, and we argue that the hippocampus actively and automatically predicts and constructs the scenes we need to fuel our cognition.”
§ The Hippocampus: A Manifesto for Change > Conclusions
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The construction of scenes and BE involve anticipating what is likely to be beyond the view.”
§ The Hippocampus: A Manifesto for Change > Conclusions
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
The paper relies on this without support.
There is currently no unified and mechanistic account of how the hippocampus supports episodic memory, imagining the future, and spatial navigation.
“We currently lack a unified and mechanistic account of how the hippocampus supports a range of disparate cognitive functions that includes episodic memory, imagining the future, and spatial navigation.”
The paper relies on this without support.
Scenes have not featured prominently in accounts of hippocampal function.
“Up until now, scenes have not featured prominently in accounts of hippocampal function.”
The paper relies on this without support.
The memory literature is awash with experiments investigating hippocampal processes that have used scene stimuli but that pay little or no attention to the effect of the scenes themselves.
“The memory literature is awash with experiments investigating hippocampal processes (such as associative memory) that have used scene stimuli but that pay little or no attention to the effect of the scenes themselves.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In fact, previous accounts suggested that prediction and mental imagery may involve overlapping brain mechanisms [6, 43, 44], and mental imagery might have evolved from predictive brain mechanisms.”
From Decoding sound and imagery content in early visual cortex (2014) · cites this paper as [43]
Citations
Cites
The free-energy principle: a unified brain theory?
Friston, K. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2787 · Cited by 8,120 · cited 2×
“This also resonates with emerging ideas concerning prior knowledge and schema (Tse et al., 2007), templates (Dragoi & Tonegawa, 2011), and predictive coding (Friston, 2010).”
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010
LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
Scoville, W. B., & Milner, B. (1957) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.20.1.11 · Cited by 7,322 · cited 1×
“It is 56 years since formal cognitive studies of the human hippocampus began in earnest (Scoville & Milner, 1957), and yet we remain bereft of a widely agreed-upon answer to what it does.”
BackgroundThe hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat
O'Keefe, J., & Dostrovsky, J. (1971) · Brain Research · doi:10.1016/0006-8993(71)90358-1 · Cited by 6,151 · cited 1×
“The hippocampus has long been linked to spatial navigation, with place cells in the hippocampus exhibiting location-specific firing (O’Keefe & Dostrovsky, 1971).”
BackgroundMemory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
Squire, L. R. (1992) · Psychological Review · doi:10.1037/0033-295x.99.2.195 · Cited by 5,376 · cited 1×
“Nor does it appear to be specifically concerned only with the conscious (declarative) expression of long-term memory (Squire, 1992; but see Hannula & Greene, 2012).”
BackgroundThe hippocampus as a cognitive map
Passingham, R. E. (1979) · Neuroscience · doi:10.1016/0306-4522(79)90015-0 · Cited by 5,128
Episodic memory: from mind to brain
Tulving, E. (2002) · Annual Review of Psychology · doi:10.1146/annurev.psych.53.100901.135114 · Cited by 4,950 · cited 2×
“One process that episodic memory and imagining future events seem to share is a subjective sense of the self over time (“autonoesis”; Tulving, 2002), which is closely coupled with the capacity for mental time travel (the ability to project oneself forwards or backwards in time).”
BackgroundTulving, E. (1985) · Canadian Psychology / Psychologie canadienne · doi:10.1037/h0080017 · Cited by 4,638
Functional-anatomic fractionation of the brain’s default network
Andrews-Hanna, J. R., Reidler, J. S., Sepulcre, J., Poulin, R., & Buckner, R. L. (2010) · Neuron · doi:10.1016/j.neuron.2010.02.005 · Cited by 2,767
Buckner, R. L., & Carroll, D. C. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.11.004 · Cited by 2,691
Cited by
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Episodic memory and beyond: the hippocampus and neocortex in transformation
Moscovitch, M., Cabeza, R., Winocur, G., & Nadel, L. (2016) · Annual Review of Psychology · doi:10.1146/annurev-psych-113011-143733 · Cited by 1,062
“…in healthy controls in fMRI studies, was similar to that obtained on recall of autobiographical episodes (BenYakov & Dudai 2011, Furman et al. 2012, Maguire & Mullally 2013) [Supplemental Figure 3 (follow the Supplemental Material link in the online version of this article or at http://…”
InfluentialCan We Reconcile the Declarative Memory and Spatial Navigation Views on Hippocampal Function?
Eichenbaum, H., & Cohen, N. J. (2014) · Neuron · doi:10.1016/j.neuron.2014.07.032 · Cited by 654
Anterior hippocampus: the anatomy of perception, imagination and episodic memory
Zeidman, P., & Maguire, E. A. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2015.24 · Cited by 542
Self-citationA map for social navigation in the human brain
Tavares, R. M., Mendelsohn, A., Grossman, Y., Williams, C. H., Shapiro, M., Trope, Y., & Schiller, D. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.011 · Cited by 505
“More recent work suggests that the hippocampus constructs spatially coherent scenes that are representative egocentrically (Maguire and Mullally, 2013).”
The role of the hippocampus in flexible cognition and social behavior
Rubin, R. D., Watson, P. D., Duff, M. C., & Cohen, N. J. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00742 · Cited by 489
“…with points of emphasis of other contemporary investigators, including ideas about the role of the hippocampus in scene (re)construction (e.g., Maguire and Mullally, 2013), and in the generation of simulated future events (Buckner and Carroll, 2007), as well as the functional relationship…”
Event memory: A theory of memory for laboratory, autobiographical, and fictional events.
Rubin, D. C., & Umanath, S. (2015) · Psychological Review · doi:10.1037/a0037907 · Cited by 379
“For event memory, the function of the hippocampus in the construction of a detailed scene is stressed, a function that is common to many other tasks (Maguire & Mullally, 2013).”
BackgroundMethodInfluentialScene Perception in the Human Brain
Epstein, R. A., & Baker, C. I. (2019) · Annual Review of Vision Science · doi:10.1146/annurev-vision-091718-014809 · Cited by 370
“…this structure exclusively supports memory, alternative theories propose that it plays a central role in scene construction—that is, the bringing together of elements from memory or the imagination into a coherent spatial framework (Maguire & Mullally 2013)—or scene perception (Graham et al. 2010).”
BackgroundFrom Knowing to Remembering: The Semantic–Episodic Distinction
Renoult, L., Irish, M., Moscovitch, M., & Rugg, M. D. (2019) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2019.09.008 · Cited by 397
“Thus, while the hippocampus has been ascribed a central role in constructing the requisite spatial context across past, future, and hypothetical scenarios [173–176], it may be important to consider the role of other structures and laterality effects in this context.”
BackgroundWhy do we remember? The communicative function of episodic memory
Mahr, J. B., & Csibra, G. (2017) · Behavioral and Brain Sciences · doi:10.1017/s0140525x17000012 · Cited by 371
“The neural substrate of this “scenario construction system” is localized in the medial temporal lobes, specifically in the hippocampus (Cheng et al. 2016; Maguire & Mullally 2013; Maguire et al. 2015).”
Decoding sound and imagery content in early visual cortex
Vetter, P., Smith, F. W., & Muckli, L. (2014) · Current Biology · doi:10.1016/j.cub.2014.04.020 · Cited by 323
“In fact, previous accounts suggested that prediction and mental imagerymay involve overlapping brainmechanisms [6, 43, 44], and mental imagery might have evolved from predictive brain mechanisms.”
Memory and Space: Towards an Understanding of the Cognitive Map
Schiller, D., Eichenbaum, H., Buffalo, E. A., Davachi, L., Foster, D. J., Leutgeb, S., & Ranganath, C. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2618-15.2015 · Cited by 340
“…suggested that memory and spatial navigation both rely on neural machinery that represents space as a mental map of interconnected locations; and Maguire and Mullally (2013) theorized that the primary role of hippocampus is the construction of spatially coherent scenes, which is critical and…”
BackgroundRobin, J., & Moscovitch, M. (2017) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2017.07.016 · Cited by 266
Space, time, and episodic memory: The hippocampus is all over the cognitive map
Ekstrom, A. D., & Ranganath, C. (2017) · Hippocampus · doi:10.1002/hipo.22750 · Cited by 278
“Based on such findings, Maguire and colleagues (Maguire & Mullally, 2013; Mullally & Maguire, 2014) proposed “scene construction theory” (“SCT”), which argues that, “....the hippocampus primarily acts to facilitate the construction of atemporal scenes and in doing so allows the event details of…”
BackgroundMemory, Imagination, and Predicting the Future
Mullally, S. L., & Maguire, E. A. (2013) · The Neuroscientist · doi:10.1177/1073858413495091 · Cited by 278
“Thus, the idea of mental time travel has undoubted heuristic value and may account for the contributions of some areas in the core network to imagining the future, but not the hippocampus.”
BackgroundSelf-citationRemote Memory and the Hippocampus: A Constructive Critique
Barry, D. N., & Maguire, E. A. (2018) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2018.11.005 · Cited by 210
Self-citationMechanisms for widespread hippocampal involvement in cognition.
Shohamy, D., & Turk-Browne, N. B. (2013) · Journal of Experimental Psychology: General · doi:10.1037/a0034461 · Cited by 187
“On the other hand, hippocampal damage can impair scene discrimination (Lee et al., 2013; Maguire & Mullally, 2013), in addition to the impairment of object recognition caused by perirhinal damage (Saksida & Bussey, 2010; Yeung et al., 2013).”
BackgroundConstructing, Perceiving, and Maintaining Scenes: Hippocampal Activity and Connectivity
Zeidman, P., Mullally, S. L., & Maguire, E. A. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu266 · Cited by 187
“Key words: episodic memory, fMRI, hippocampus, perception, scene construction, scenes”
BackgroundSelf-citationMcCormick, C., Ciaramelli, E., Luca, F. D., & Maguire, E. A. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.07.066 · Cited by 174
“…mental scenes in which details can be bound to be re- or pre-experienced (Clark and Maguire, 2016; Hassabis and Maguire, 2009; Maguire et al., 2016; Maguire and Mullally, 2013; Zeidman and Maguire, 2016; but see Kim et al., 2015; Kim et al., 2011 for an alternative view that the hippocampus…”
InfluentialSelf-citationThe role of the hippocampus in memory and mental construction
Sheldon, S., & Levine, B. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13006 · Cited by 155
Mind-Wandering in People with Hippocampal Damage
McCormick, C., Rosenthal, C. R., Miller, T. D., & Maguire, E. A. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1812-17.2018 · Cited by 146
“A scene construction deficit has been implicated in the impaired autobiographical memory and future thinking of patients with hippocampal damage (Hassabis and Maguire, 2007; Maguire and Mullally, 2013; Clark and Maguire, 2016).”
Self-citationCognitive neuroscience of human counterfactual reasoning
Hoeck, N. V. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00420 · Cited by 147
“…network critically contributes to behavioral regulation and feelings of regret by updating and maintaining counterfactual action-outcome information and signaling when it becomes profitable to change behavior (Liu et al., 2007; Nicolle et al., 2011b; Hampshire et al., 2012; Rudebeck et al., 2013).”
BackgroundHippocampal-targeted Theta-burst Stimulation Enhances Associative Memory Formation
Tambini, A., Nee, D. E., & D’Esposito, M. (2018) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01300 · Cited by 129
“These findings are consistent with prior evidence that these regions cluster together to comprise a functional network (Maguire & Mullally, 2013; Vann, Aggleton, & Maguire, 2009), corresponding to the proposed posterior–medial memory network (Ritchey, Yonelinas, & Ranganath, 2014; Ranganath &…”
A network linking scene perception and spatial memory systems in posterior cerebral cortex
Steel, A., Billings, M. M., Silson, E. H., & Robertson, C. E. (2021) · Nature Communications · doi:10.1038/s41467-021-22848-z · Cited by 132
vmPFC Drives Hippocampal Processing during Autobiographical Memory Recall Regardless of Remoteness
McCormick, C., Barry, D. N., Jafarian, A., Barnes, G. R., & Maguire, E. A. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa172 · Cited by 125
“…(Nadel and Moscovitch 1997; Robin and Moscovitch 2017; Moscovitch and Nadel 2019), or for recollecting vivid and rich AMs of any age because it constructs the scenes that are central to re-experiencing past events (Maguire and Mullally 2013; Zeidman and Maguire 2016; Barry and Maguire 2019a,b).”
BackgroundSelf-citationScenes, Spaces, and Memory Traces
Maguire, E. A., Intraub, H., & Mullally, S. L. (2015) · The Neuroscientist · doi:10.1177/1073858415600389 · Cited by 114
Self-citationKlein, S. B. (2014) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1333 · Cited by 136
Sheldon, S., Farb, N., Palombo, D. J., & Levine, B. (2016) · Cortex · doi:10.1016/j.cortex.2015.11.005 · Cited by 104
“Based on the contemporary view that the same processes that support experiencing the past support event memory and event simulations in general (Maguire & Mullally, 2013; Rubin & Umanath, 2015; Schacter & Addis, 2009), we further predict that endorsing episodic remembering processes that promote…”
Ventromedial prefrontal damage causes a pervasive impairment of episodic memory and future thinking
Bertossi, E., Tesini, C., Cappelli, A., & Ciaramelli, E. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2016.01.034 · Cited by 101
“…intact declarative memory. vmPFC, therefore, may be crucial to assemble complex (extended) events, probably mediating episodic memory processes (e.g., search, binding) that also operate during more traditional episodic memory tasks, such as list learning (see also Maguire and Mullally, 2013).”
The spatial scaffold: The effects of spatial context on memory for events.
Robin, J., Wynn, J. S., & Moscovitch, M. (2015) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037/xlm0000167 · Cited by 125
Two years later – Revisiting autobiographical memory representations in vmPFC and hippocampus
Bonnici, H. M., & Maguire, E. A. (2017) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.05.014 · Cited by 117
“First, recent and remote autobiographical memory representations were distinguishable in the hippocampus, in line with theories that purport a role for the hippocampus in the vivid recall of such memories for a lifetime (Nadel and Moscovitch, 1997; Winocur and Moscovitch, 2011; Moscovitch et al., 2016; Hassabis and Ma…”
BackgroundResultSelf-citationKim, H. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.11.006 · Cited by 114
Investigating the functions of subregions within anterior hippocampus
Zeidman, P., Lutti, A., & Maguire, E. A. (2015) · Cortex · doi:10.1016/j.cortex.2015.09.002 · Cited by 99
“…these results are better supported by models which propose involvement of the hippocampus in vivid recall in perpetuity, such as multiple trace theory (Nadel & Moscovitch, 1997; Winocur & Moscovitch, 2011) and the scene construction theory (Hassabis & Maguire, 2007; Maguire & Mullally, 2013).”
BackgroundMethodSelf-citationA Neurocognitive Perspective on the Forms and Functions of Autobiographical Memory Retrieval
Sheldon, S., Fenerci, C., & Gurguryan, L. (2019) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2019.00004 · Cited by 115
“During autobiographical memory retrieval, the hippocampus associates and integrates information from larger processing systems to access memory details to form a coherent mental representation (Nadel and Moscovitch, 1997; Hassabis and Maguire, 2009; Winocur and Moscovitch, 2011; Maguire and Mullally, 2013;Moscovitch e…”
BackgroundRosenbaum, R. S., Kim, A. S. N., & Baker, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.21037-7 · Cited by 111
The Neural Dynamics of Novel Scene Imagery
Barry, D. N., Barnes, G. R., Clark, I. A., & Maguire, E. A. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.2497-18.2019 · Cited by 102
“In this context, a scene is defined as a naturalistic 3D spatially coherent representation of the world typically populated by objects and viewed from an egocentric perspective (Maguire and Mullally, 2013; Dalton et al., 2018).”
BackgroundInfluentialSelf-citationLearning to remember: The early ontogeny of episodic memory
Mullally, S. L., & Maguire, E. A. (2014) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2013.12.006 · Cited by 108
“Spatial cognition alone (upon which episodic memory is considered to reside; O’Keefe and Nadel, 1978; Burgess et al., 2002; Maguire and Mullally, 2013) represents a complex set of cognitive processes which appear to mature at different rates throughout early and middle childhood (Sluzenski et al.”
BackgroundSelf-citationA central role for the retrosplenial cortex in de novo environmental learning
Auger, S. D., Zeidman, P., & Maguire, E. A. (2015) · eLife · doi:10.7554/elife.09031 · Cited by 99
Self-citationInternally generated hippocampal sequences as a vantage point to probe future‐oriented cognition
Pezzulo, G., Kemere, C. T., & van der Meer, M. A. A. (2017) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13329 · Cited by 98
Klein, S. B. (2016) · Quarterly Journal of Experimental Psychology · doi:10.1080/17470218.2015.1007150 · Cited by 92
Solving the detour problem in navigation: a model of prefrontal and hippocampal interactions
Spiers, H. J., & Gilbert, S. J. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00125 · Cited by 94
“Current theories would suggest the hippocampus is needed in order to construct detailed precise spatial representations, and the coarse schematic representations of the environment can be formed elsewhere (Moscovitch et al., 2005; Tse et al., 2007; Maguire and Mullally, 2013).”
BackgroundResultMoral imagination: Facilitating prosocial decision-making through scene imagery and theory of mind
Gaesser, B., Keeler, K., & Young, L. (2017) · Cognition · doi:10.1016/j.cognition.2017.11.004 · Cited by 98
“…is broadly thought to be an important component of imagining vivid scenes (a view most prominently developed by Maguire and colleagues (see Maguire & Mullally, 2013 for review, but see also Addis & Schacter, 2012; Andrews-Hanna, Reidler, Huang, & Buckner, 2010; Rubin & Umanath, 2015;…”
BackgroundAssessing the mechanism of response in the retrosplenial cortex of good and poor navigators
Auger, S. D., & Maguire, E. A. (2013) · Cortex · doi:10.1016/j.cortex.2013.08.002 · Cited by 98
“…upon which other brain areas (e.g., the hippocampus) can then build effective spatial and scene representations that are central to episodicmemories, imagining the future and spatial navigation (Hassabis & Maguire, 2007; Maguire & Mullally, 2013; Ranganath & Ritchey, 2012; Schacter et al., 2012).”
Self-citationMemory, scene construction, and the human hippocampus
Kim, S., Dede, A. J. O., Hopkins, R. O., & Squire, L. R. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1503863112 · Cited by 97
“Its possible role in spatial processing has been recently explored in humans as well (5), and it has been proposed that the human hippocampus is essential for the ability to construct spatially coherent scenes (6, 7).”
BackgroundMethodDalton, M. A., McCormick, C., & Maguire, E. A. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.02.066 · Cited by 94
“These representations, in turn, are held to underpin the scene-based cognition upon which episodic memory, imagination of fictitious or future scenarios and mind wandering are dependent (Maguire and Mullally, 2013; McCormick et al., 2018).”
BackgroundSelf-citationThe Primacy of Spatial Context in the Neural Representation of Events
Robin, J., Buchsbaum, B. R., & Moscovitch, M. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1638-17.2018 · Cited by 94
“…plays an especially important role in determining the neural representation of an event, consistent with scene construction and related theories (O’Keefe and Nadel, 1978; Nadel, 1991; Burgess et al., 2002; Hassabis and Maguire, 2007, 2009; Maguire and Mullally, 2013; Nadel and Peterson, 2013).”
BackgroundResultInfluentialSpatial scaffold effects in event memory and imagination
Robin, J. (2018) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1462 · Cited by 99
Billig, A. J., Lad, M., Sedley, W., & Griffiths, T. D. (2022) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2022.102326 · Cited by 92
“, 2013), associating disparate elements of a scene (Graham et al., 2010; Maguire and Mullally, 2013; Olsen et al., 2012), structuring conceptual knowledge (Behrens et al.”
BackgroundHuman hippocampal CA3 damage disrupts both recent and remote episodic memories
Miller, T. D., Chong, T. T. ‐., Davies, A. M. A., Johnson, M. R., Irani, S. R., Husain, M., Ng, T. W. C., Jacob, S., Maddison, P., Kennard, C., et al. (2020) · eLife · doi:10.7554/elife.41836 · Cited by 85
Imagination as a fundamental function of the hippocampus
Comrie, A. E., Frank, L. M., & Kay, K. (2022) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2021.0336 · Cited by 91
“These results highlight that the hippocampus, along with other brain regions in the default mode network, is important for the capacity to generate mental displacements from actual present circumstances, whether in time, space, personal perspective and possibly other domains [14,17,19,28,29].”
BackgroundThe MNESIS model: Memory systems and processes, identity and future thinking
Eustache, F., Viard, A., & Desgranges, B. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2016.05.006 · Cited by 94
Dalton, M. A., Zeidman, P., Barry, D. N., Williams, E. J., & Maguire, E. A. (2017) · Brain and Neuroscience Advances · doi:10.1177/2398212817701448 · Cited by 74
“The human hippocampus is implicated in a wide range of cognitive processes including episodic memory, future thinking, navigation and aspects of perception (Maguire and Mullally, 2013; Schacter et al., 2012; Zeidman and Maguire, 2016).”
BackgroundSelf-citationBellana, B., Liu, Z. ‐., Diamond, N. B., Grady, C. L., & Moscovitch, M. (2017) · Human Brain Mapping · doi:10.1002/hbm.23445 · Cited by 75
“Some processes attributed to these regions include scene and event construction [Maguire and Mullally, 2013], detail generation [Rosenbaum et al.”
BackgroundBertossi, E., Aleo, F., Braghittoni, D., & Ciaramelli, E. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.12.015 · Cited by 74
Differentiable Processing of Objects, Associations, and Scenes within the Hippocampus
Dalton, M. A., Zeidman, P., McCormick, C., & Maguire, E. A. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0263-18.2018 · Cited by 73
“, 2007; Hannula and Ranganath, 2008), constructing mental representations of scenes (Maguire and Mullally, 2013; Zeidman and Maguire, 2016), imagining the future (Hassabis et al.”
BackgroundInfluentialSelf-citationThe Role of the Human Entorhinal Cortex in a Representational Account of Memory
Schultz, H., Sommer, T., & Peters, J. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00628 · Cited by 73
“In this Mini Review, we review these findings and discuss how they relate to the animal literature.”
BackgroundScenes enable a sense of reliving: Implications for autobiographical memory
Rubin, D. C., Deffler, S. A., & Umanath, S. (2018) · Cognition · doi:10.1016/j.cognition.2018.10.024 · Cited by 80
“The parahippocampal cortex is active for objects that evoke a strong sense of the surrounding space compared to ones that do not (Mullally & Maguire, 2011, 2013).”
BackgroundContributions of cortical feedback to sensory processing in primary visual cortex
Petro, L. S., Vizioli, L., & Muckli, L. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01223 · Cited by 61
“The hippocampus exerts top–down effects on early vision during scene extrapolation (Chadwick et al., 2013), prompting new theories of hippocampal memory whereby it constructs the “world beyond the immediate sensorium” (Maguire and Mullally, 2013).”
BackgroundActive Navigation in Virtual Environments Benefits Spatial Memory in Older Adults
Meade, M. E., Meade, J., Sauzeon, H., & Fernandes, M. A. (2019) · Brain Sciences · doi:10.3390/brainsci9030047 · Cited by 67
“Evidence suggests that degradation in the hippocampal region is related to declines in survey abilities in older adults [58,59] and also to visual perceptual processing [60], which may be involved in spatial scene construction abilities that are supported by the hippocampus [61,62].”
BackgroundThe human hippocampus is sensitive to the durations of events and intervals within a sequence
Barnett, A. J., O’Neil, E. B., Watson, H. C., & Lee, A. C. H. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.09.011 · Cited by 70
Moscovitch, M., & Gilboa, A. (2021) · PsyArXiv (OSF Preprints) · doi:10.31234/osf.io/yxbrs · Cited by 68
Episodic simulation reduces intergroup bias in prosocial intentions and behavior.
Gaesser, B., Shimura, Y., & Cikara, M. (2019) · Journal of Personality and Social Psychology · doi:10.1037/pspi0000194 · Cited by 66
“…and people integrated into a vivid, coherent sensory experience that unfolds over time as a specific event or episode (Mullally, Intraub, & Maguire, 2012; Maguire & Mullally, 2013; see also Addis & Schacter, 2012; Andrews-Hanna, Reidler, Sepulcre, Poulin, & Buckner, 2010; Rubin & Umanath, 2015).”
BackgroundA conceptual space for episodic and semantic memory
Rubin, D. C. (2021) · Memory & Cognition · doi:10.3758/s13421-021-01148-3 · Cited by 72
“The parahippocampal cortex is active for objects that evoke a strong sense of the surrounding space compared with ones that do not (Mullally & Maguire, 2013).”
BackgroundRobin, J., Hirshhorn, M., Rosenbaum, R. S., Winocur, G., Moscovitch, M., & Grady, C. L. (2014) · Hippocampus · doi:10.1002/hipo.22352 · Cited by 68
Remembering Preservation in Hippocampal Amnesia
Clark, I. A., & Maguire, E. A. (2015) · Annual Review of Psychology · doi:10.1146/annurev-psych-122414-033739 · Cited by 68
“Maguire & Mullally (2013) go further and suggest that any task or any aspect of cognition that requires an internal model of a scene will be adversely affected by bilateral hippocampal lesions.”
InfluentialSelf-citationRyals, A. J., Wang, J. X., Polnaszek, K. L., & Voss, J. L. (2015) · Hippocampus · doi:10.1002/hipo.22425 · Cited by 66
Nawa, N. E., & Ando, H. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.01.042 · Cited by 66
“, remembering the past, envisioning the future, conceiving the viewpoint of others, and possibly spatial navigation, though alternative views have been put forward to explain these commonalities as well (Hassabis and Maguire, 2009; Maguire and Mullally, 2013).”
Do questionnaires reflect their purported cognitive functions?
Clark, I. A., & Maguire, E. A. (2019) · Cognition · doi:10.1016/j.cognition.2019.104114 · Cited by 77
Self-citationMcCrory, E. J. P., Puetz, V. B., Maguire, E. A., Mechelli, A., Palmer, A. L., Gerin, M. I., Kelly, P. A., Koutoufa, I., & Viding, E. M. (2017) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.117.201798 · Cited by 61
Self-citationMonzel, M., Vetterlein, A., & Reuter, M. (2022) · Journal of Neuropsychology · doi:10.1111/jnp.12265 · Cited by 56
Effects of prospective thinking on intertemporal choice: the role of familiarity
Sasse, L. K., Peters, J., Büchel, C., & Brassen, S. (2015) · Human Brain Mapping · doi:10.1002/hbm.22912 · Cited by 54
“It seems likely that the hippocampus is generally involved in the episodic construction of future events [Hassabis et al., 2007; Maguire and Mullally, 2013].”
BackgroundMacDonald, C. J., Fortin, N. J., Sakata, S., & Meck, W. H. (2014) · Timing & Time Perception · doi:10.1163/22134468-00002020 · Cited by 56
“…contributes to prospective timing mediated by other neural circuits in service of cognition and emotion (Coull et al., 2013; Droit-Volet & Meck, 2007; Droit-Volet et al., 2013; Howard & Eichenbaum, 2013; Maguire & Mullally, 2013; Meck & Benson, 2002; Meck & MacDonald, 2007; Nadel & Peterson, 2013).”
BackgroundReggente, N., Essoe, J. K.-Y., Baek, Y. H., & Rissman, J. (2019) · Journal of Cognitive Enhancement · doi:10.1007/s41465-019-00141-8 · Cited by 62
Familiar real-world spatial cues provide memory benefits in older and younger adults.
Robin, J., & Moscovitch, M. (2017) · Psychology and Aging · doi:10.1037/pag0000162 · Cited by 60
Dreaming with hippocampal damage
Spanò, G., Pizzamiglio, G., McCormick, C., Clark, I. A., De Felice, S., Miller, T. D., Edgin, J. O., Rosenthal, C. R., & Maguire, E. A. (2020) · eLife · doi:10.7554/elife.56211 · Cited by 47
Self-citationHippocampal Damage Increases Deontological Responses during Moral Decision Making
McCormick, C., Rosenthal, C. R., Miller, T. D., & Maguire, E. A. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0707-16.2016 · Cited by 53
“However, what is clear across a number of different cognitive domains is that patients with hippocampal damage have a reduced ability to mentally construct spatially coherent scenes (Maguire and Mullally, 2013; Clark and Maguire, 2016; Zeidman and Maguire, 2016).”
BackgroundSelf-citationPalombo, D. J., Hayes, S. M., Peterson, K. M., Keane, M. M., & Verfaellie, M. H. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw381 · Cited by 49
Network-wide abnormalities explain memory variability in hippocampal amnesia
Argyropoulos, G. P. D., Loane, C., Roca‐Fernández, A., Lage-Martinez, C., Gurau, O., Irani, S. R., & Butler, C. (2019) · eLife · doi:10.7554/elife.46156 · Cited by 50
The Hippocampal Horizon: Constructing and Segmenting Experience for Episodic Memory
Ross, T. W., & Easton, A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.11.038 · Cited by 50
Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia
Monzel, M., Leelaarporn, P., Lutz, T., Schultz, J., Brunheim, S., Reuter, M., & McCormick, C. (2024) · eLife · doi:10.7554/elife.94916 · Cited by 68
“The scene construction theory states that the hippocampus is crucially needed for the construction of spatially coherent mental models of scenes ( Maguire and Mullally, 2013 ).”
BackgroundMemory Retrieval in Mice and MenPreprint
Ben-Yakov, A., Dudai, Y., & Mayford, M. R. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021790 · Cited by 54
Scene construction in developmental amnesia: An fMRI study
Mullally, S. L., Vargha‐Khadem, F., & Maguire, E. A. (2013) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2013.11.001 · Cited by 54
Self-citationDeciding what is possible and impossible following hippocampal damage in humans
McCormick, C., Rosenthal, C. R., Miller, T. D., & Maguire, E. A. (2016) · Hippocampus · doi:10.1002/hipo.22694 · Cited by 48
Self-citationVerbal Paired Associates and the Hippocampus: The Role of Scenes
Clark, I. A., kim, M.-S., & Maguire, E. A. (2018) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01315 · Cited by 52
Self-citationHerdman, K. A., Calarco, N., Moscovitch, M., Hirshhorn, M., & Rosenbaum, R. S. (2015) · Cortex · doi:10.1016/j.cortex.2015.06.008 · Cited by 46
“Our findings also have implications for two recently developed theoretical accounts, the Transformation Hypothesis (Winocur, Moscovitch, & Sekeres, 2007; Winocur & Moscovitch, 2011) and Scene Construction Theory (Maguire & Mullally, 2013).”
Geiller, T., Royer, S., & Choi, J.-S. (2017) · Experimental Neurobiology · doi:10.5607/en.2017.26.1.1 · Cited by 50
“In fact, the hippocampus is associated with multiple brain functions but no single model addresses the issue of how it manages to accomplish these various tasks [77, 78].”
BackgroundVerfaellie, M. H., Knoff, A. A. W., Reid, A. G., Race, E., & Keane, M. M. (2019) · Cortex · doi:10.1016/j.cortex.2019.01.028 · Cited by 47
The dimensions of episodic simulation
Mahr, J. B. (2020) · Cognition · doi:10.1016/j.cognition.2019.104085 · Cited by 50
Monk, A. M., Dalton, M. A., Barnes, G. R., & Maguire, E. A. (2020) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01634 · Cited by 50
“…hippocampal activity during immediate scene construction (where participants had 3 sec to immediately imagine a full scene; Barry, Barnes, et al., 2019) and also in the very earliest stage of autobiographical memory retrieval, which also involves scene construction (McCormick et al., 2020).”
BackgroundSelf-citationA critical role of the human hippocampus in an electrophysiological measure of implicit memory
Addante, R. J. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2014.12.069 · Cited by 51
“However, this framework has gradually begun to erode (Chun and Phelps, 1999; Hannula and Greene, 2012; Maguire and Mullally, 2013; Henke, 2010; Ranganath and Ritchey, 2012).”
BackgroundGrilli, M. D., Knoff, A. A. W., Bercel, J. J., & Ryan, L. (2018) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617718000577 · Cited by 52
“The ability to form a vivid scene is dependent on the MTL (Hassabis et al., 2007; Maguire & Mullally, 2013; Palombo, Hayes, et al., 2018) and frontal and parietal lobe regions (Irish et al., 2015; Summerfield, Hassabis, & Maguire, 2010), likely because of shared contributions to spatial-perceptual…”
BackgroundIdentifying the cognitive processes underpinning hippocampal-dependent tasks.
Clark, I. A., Hotchin, V., Monk, A. M., Pizzamiglio, G., Liefgreen, A., & Maguire, E. A. (2019) · Journal of Experimental Psychology General · doi:10.1037/xge0000582 · Cited by 49
“Nevertheless, navigation has long been associated with hippocampal function (Maguire et al., 2000; O’Keefe & Nadel, 1978) and more recently with scene construction (Maguire & Mullally, 2013).”
BackgroundInfluentialSelf-citationRepresentation of Contralateral Visual Space in the Human Hippocampus
Silson, E. H., Zeidman, P., Knapen, T. H. J., & Baker, C. I. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1990-20.2020 · Cited by 47
Palermo, L., Boccia, M., Piccardi, L., & Nori, R. (2022) · Consciousness and Cognition · doi:10.1016/j.concog.2022.103360 · Cited by 51
Altered Intrinsic Regional Activity and Interregional Functional Connectivity in Post-stroke Aphasia
Yang, M., Li, J., Li, Y., Li, R., Pang, Y., Yao, D., Liao, W., & Chen, H. (2016) · Scientific Reports · doi:10.1038/srep24803 · Cited by 43
Evidencing a place for the hippocampus within the core scene processing network
Hodgetts, C. J., Shine, J. P., Lawrence, A. D., Downing, P. E., & Graham, K. S. (2016) · Human Brain Mapping · doi:10.1002/hbm.23275 · Cited by 48
“, 2013] and contributions to scene construction [Maguire and Mullally, 2013; Zeidman et al., 2015].”
BackgroundInfluentialPeukert, X., Steindorf, K., Schagen, S. B., Runz, A., Meyer, P., & Zimmer, P. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00147 · Cited by 42
Perceptual similarity and the neural correlates of geometrical illusions in human brain structure
Axelrod, V., Schwarzkopf, D. S., Gilaie‐Dotan, S., & Rees, G. E. (2017) · Scientific Reports · doi:10.1038/srep39968 · Cited by 41
Scene Construction and Relational Processing: Separable Constructs?
Roberts, R. P., Schacter, D. L., & Addis, D. R. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx081 · Cited by 45
The Hippocampus and Social Cognition
Laurita, A. C., & Spreng, R. N. (2017) · Springer eBooks · doi:10.1007/978-3-319-50406-3_17 · Cited by 42
How Imagination and Memory Shape the Moral Mind
O’Connor, B. B., & Fowler, Z. (2022) · Personality and Social Psychology Review · doi:10.1177/10888683221114215 · Cited by 41
“…of an episode is thought to serve as a platform on which fragmented details can be combined into an integrated representation and vividly experienced (Addis & Schacter, 2012; Maguire & Hassabis, 2011; Maguire & Mullally, 2013; Robin, 2018; Robin et al., 2016, 2018; Suddendorf & Corballis, 2007).”
Background
Metadata
- Authors
- Maguire, E. A., & Mullally, S. L.
- Affiliations
- Wellcome Centre for Human Neuroimaging (GB)
- Corresponding author
- Maguire, Eleanor A.
- Venue
- Journal of Experimental Psychology: General
- Published
- 2013-11
- Volume
- 142
- Issue
- 4
- Pages
- 1180-1189
- ISSN
- 0096-3445 (ISSN-L)
- 1939-2222
- PMC
- PMC3906798
- OpenAlex
- W2103374823
- Semantic Scholar
- d2c54fbe4881e323a62d8b1d9924facd4f6a889a
- Cited by
- 393
- References
- 75
- Citations by year
- 2026: 25 · 2025: 29 · 2024: 37 · 2023: 23 · 2022: 28 · 2021: 25 · 2020: 57 · 2019: 37 · 2018: 28 · 2017: 36 · 2016: 17 · 2015: 26 · 2014: 18 · 2013: 7
- FWCI
- 12.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Experimental Psychology General (publishedVersion, other-oa)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity) (cc-by)
- Funders
- Wellcome Trust
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Spatial Cognition and Navigation
- Keywords
- hippocampus, episodic memory, scene memory, spatial navigation, future imaginings, memory architecture, hippocampal dysfunction, scene construction
- MeSH terms
- Cognition, Hippocampus, Humans, Imagination, Memory, Space Perception, Spatial Behavior
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