Solving the detour problem in navigation: a model of prefrontal and hippocampal interactions
Open accessAbstract
Adapting behavior to accommodate changes in the environment is an important function of the nervous system. A universal problem for motile animals is the discovery that a learned route is blocked and a detour is required. Given the substantial neuroscience research on spatial navigation and decision-making it is surprising that so little is known about how the brain solves the detour problem. Here we review the limited number of relevant functional neuroimaging, single unit recording and lesion studies. We find that while the prefrontal cortex (PFC) consistently responds to detours, the hippocampus does not. Recent evidence suggests the hippocampus tracks information about the future path distance to the goal. Based on this evidence we postulate a conceptual model in which: Lateral PFC provides a prediction error signal about the change in the path, frontopolar and superior PFC support the re-formulation of the route plan as a novel subgoal and the hippocampus simulates the new path. More data will be required to validate this model and understand (1) how the system processes the different options; and (2) deals with situations where a new path becomes available (i.e., shortcuts).
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Rodents with HPC lesions and extensive pre-lesion experience in an environment are able to use the overall layout of the learned environment, or its spatial gist.
“This ditinction is similar to that found in rodents with HPC lesions and extensive pre-lesion experience in an environment: they are able to use the overall layout of the learned environment, or its spatial gist, and take detours to reach goal locations, although often not the most optimal ones 70,125,126 .”
From From cognitive maps to spatial schemas (2023) · cites this paper as [126]
Rodents with HPC lesions and extensive pre-lesion experience take detours to reach goal locations, although often not the most optimal ones.
“they are able to use the overall layout of the learned environment, or its spatial gist, and take detours to reach goal locations, although often not the most optimal ones 70,125,126 .”
From From cognitive maps to spatial schemas (2023) · cites this paper as [126]
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Cites
Reinforcement Learning: An Introduction
Sutton, R. S., & Barto, A. G. (1998) · IEEE Transactions on Neural Networks · doi:10.1109/tnn.1998.712192 · Cited by 27,225 · see citing works
An Integrative Theory of Prefrontal Cortex Function
Miller, E. K., & Cohen, J. D. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.167 · Cited by 12,803 · see citing works
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010 · see citing works
LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
Scoville, W. B., & Milner, B. (1957) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.20.1.11 · Cited by 7,322 · see citing works
Introduction to Reinforcement Learning
Sutton, R. S., & Barto, A. G. (1998) · The MIT Press eBooks · Cited by 6,855 · see citing works
Cognitive maps in rats and men
Tolman, E. C. (1948) · Psychological Review · doi:10.1037/h0061626 · Cited by 6,641 · see citing works
Place navigation impaired in rats with hippocampal lesions
Morris, R. G. M., Garrud, P., Rawlins, J. N. P., & O'Keefe, J. (1982) · Nature · doi:10.1038/297681a0 · Cited by 6,340 · see citing works
The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat
O'Keefe, J., & Dostrovsky, J. (1971) · Brain Research · doi:10.1016/0006-8993(71)90358-1 · Cited by 6,151 · see citing works
Microstructure of a spatial map in the entorhinal cortex
Hafting, T., Fyhn, M., Molden, S., Moser, M.-B., & Moser, E. I. (2005) · Nature · doi:10.1038/nature03721 · Cited by 4,068 · see citing works
Specific impairments of planning
Shallice, T. (1982) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1982.0082 · Cited by 3,741 · see citing works
Higher cortical functions in man
Lurii︠a︡, A. R., Teuber, H., Pribram, K. H., & Haigh, B. (1966) · Basic Books · Cited by 2,858 · see citing works
Common regions of the human frontal lobe recruited by diverse cognitive demands
Duncan, J., & Owen, A. M. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01633-7 · Cited by 2,498 · see citing works
Effects of Different Brain Lesions on Card Sorting: The Role of the Frontal Lobes
MILNER, B. (1963) · Archives of Neurology · doi:10.1001/archneur.1963.00460070100010 · Cited by 2,217 · see citing works
DEFICITS IN STRATEGY APPLICATION FOLLOWING FRONTAL LOBE DAMAGE IN MAN
SHALLICE, T., & BURGESS, P. W. (1991) · Brain · doi:10.1093/brain/114.2.727 · Cited by 2,017 · see citing works
The multiple-demand (MD) system of the primate brain: mental programs for intelligent behaviour
Duncan, J. (2010) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.01.004 · Cited by 1,846 · see citing works
Taube, J., Muller, R., & Ranck, J. (1990) · The Journal of Neuroscience · doi:10.1523/jneurosci.10-02-00420.1990 · Cited by 1,809 · see citing works
Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans
Aron, A. R., Fletcher, P. C., Bullmore, E. T., Sahakian, B. J., & Robbins, T. W. (2003) · Nature Neuroscience · doi:10.1038/nn1003 · Cited by 1,771 · see citing works
Packard, M. G., & McGaugh, J. L. (1996) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1996.0007 · Cited by 1,505 · see citing works
Conjunctive Representation of Position, Direction, and Velocity in Entorhinal Cortex
Sargolini, F., Fyhn, M., Hafting, T., McNaughton, B. L., Witter, M. P., Moser, M.-B., & Moser, E. I. (2006) · Science · doi:10.1126/science.1125572 · Cited by 1,485 · see citing works
HIGHER CORTICAL FUNCTIONS IN MAN
Newcombe, F. (1967) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.30.2.190-a · Cited by 1,397 · see citing works
Interplay of Hippocampus and Prefrontal Cortex in Memory
Preston, A. R., & Eichenbaum, H. (2013) · Current Biology · doi:10.1016/j.cub.2013.05.041 · Cited by 1,389 · see citing works
Knowing Where and Getting There: A Human Navigation Network
Maguire, E. A., Burgess, N., Donnett, J. G., Frackowiak, R. S. J., Frith, C. D., & O'Keefe, J. (1998) · Science · doi:10.1126/science.280.5365.921 · Cited by 1,303 · see citing works
Schemas and Memory Consolidation.
Tse, D., Langston, R. F., Kakeyama, M., Bethus, I., Spooner, P. A., Wood, E. R., Witter, M. P., & Morris, R. G. M. (2007) · Science · doi:10.1126/science.1135935 · Cited by 1,244 · see citing works
Hippocampal place-cell sequences depict future paths to remembered goals
Pfeiffer, B. E., & Foster, D. J. (2013) · Nature · doi:10.1038/nature12112 · Cited by 1,216 · see citing works
Anterior prefrontal cortex: insights into function from anatomy and neuroimaging
Ramnani, N., & Owen, A. M. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1343 · Cited by 1,170 · see citing works
Geometric determinants of the place fields of hippocampal neurons
O'Keefe, J., & Burgess, N. (1996) · Nature · doi:10.1038/381425a0 · Cited by 1,166 · see citing works
Gläscher, J., Daw, N., Dayan, P., & O'Doherty, J. P. (2010) · Neuron · doi:10.1016/j.neuron.2010.04.016 · Cited by 1,166 · see citing works
The role of the anterior prefrontal cortex in human cognition
Koechlin, É., Basso, G., Pietrini, P., Panzer, S., & Grafman, J. H. (1999) · Nature · doi:10.1038/20178 · Cited by 1,046 · see citing works
Wood, E. R., Dudchenko, P. A., Robitsek, R. J., & Eichenbaum, H. (2000) · Neuron · doi:10.1016/s0896-6273(00)00071-4 · Cited by 992 · see citing works
Prefrontal and medial temporal lobe interactions in long-term memory
Simons, J. S., & Spiers, H. J. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1178 · Cited by 961 · see citing works
Self-citationMoscovitch, M., Rosenbaum, R. S., Gilboa, A., Addis, D. R., Westmacott, R., Grady, C., McAndrews, M. P., Levine, B., Black, S., Winocur, G., et al. (2005) · Journal of Anatomy · doi:10.1111/j.1469-7580.2005.00421.x · Cited by 893 · see citing works
The gateway hypothesis of rostral prefrontal cortex (area 10) function
Burgess, P. W., Dumontheil, I., & Gilbert, S. J. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.05.004 · Cited by 753 · see citing works
Self-citationBoundary Vector Cells in the Subiculum of the Hippocampal Formation
Lever, C., Burton, S., Jeewajee, A., O'Keefe, J., & Burgess, N. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1319-09.2009 · Cited by 753 · see citing works
Etienne, A. S., & Jeffery, K. J. (2004) · Hippocampus · doi:10.1002/hipo.10173 · Cited by 726 · see citing works
Functional Specialization within Rostral Prefrontal Cortex (Area 10): A Meta-analysis
Gilbert, S. J., Spengler, S., Simons, J. S., Steele, J. D., Lawrie, S. M., Frith, C., & Burgess, P. W. (2006) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2006.18.6.932 · Cited by 681 · see citing works
Self-citationAttractor Dynamics in the Hippocampal Representation of the Local Environment
Wills, T. J., Lever, C., Cacucci, F., Burgess, N., & O'Keefe, J. M. (2005) · Science · doi:10.1126/science.1108905 · Cited by 643 · see citing works
Neurophysiology of performance monitoring and adaptive behavior
Ullsperger, M., Danielmeier, C., & Jocham, G. (2014) · Physiological Reviews · doi:10.1152/physrev.00041.2012 · Cited by 634 · see citing works
<i>Spatial Cognition and the Brain</i>
Burgess, N. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.002 · Cited by 614 · see citing works
Ragozzino, M. E., Detrick, S., & Kesner, R. P. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-11-04585.1999 · Cited by 549 · see citing works
Bohbot, V. D., Kalina, M., Stepankova, K., Spackova, N., Petrides, M., & Nadel, L. (1998) · Neuropsychologia · doi:10.1016/s0028-3932(97)00161-9 · Cited by 516 · see citing works
Are the frontal lobes implicated in “planning” functions? Interpreting data from the Tower of Hanoi
Goel, V., & Grafman, J. (1995) · Neuropsychologia · doi:10.1016/0028-3932(95)90866-p · Cited by 510 · see citing works
Model‐Based fMRI and Its Application to Reward Learning and Decision Making
O’Doherty, J. P., Hampton, A. N., & Kim, H. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1390.022 · Cited by 509 · see citing works
Insights into Human Behavior from Lesions to the Prefrontal Cortex
Szczepanski, S. M., & Knight, R. T. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.011 · Cited by 495 · see citing works
The Structure of Cognition: Attentional Episodes in Mind and Brain
Duncan, J. (2013) · Neuron · doi:10.1016/j.neuron.2013.09.015 · Cited by 471 · see citing works
Long-term plasticity in hippocampal place-cell representation of environmental geometry
Lever, C., Wills, T., Cacucci, F., Burgess, N., & O'Keefe, J. (2002) · Nature · doi:10.1038/416090a · Cited by 465 · see citing works
Gilbert, S. J., & Burgess, P. W. (2008) · Current Biology · doi:10.1016/j.cub.2007.12.014 · Cited by 455 · see citing works
Self-citationIntroduction and removal of reward, and maze performance in rats.
Tolman, E. C., & Honzik, C. H. (1930) · Cited by 447 · see citing works
The Role of Frontopolar Cortex in Subgoal Processing during Working Memory
Braver, T., & Bongiolatti, S. R. (2002) · NeuroImage · doi:10.1006/nimg.2001.1019 · Cited by 411 · see citing works
The hippocampus: a manifesto for change
Maguire, E. A., & Mullally, S. L. (2013) · Journal of Experimental Psychology: General · doi:10.1037/a0033650 · Cited by 393 · see citing works
The Neurobiology of the Prefrontal Cortex: Anatomy, Evolution, and the Origin of Insight
Passingham, R. E., & Wise, S. P. (2012) · doi:10.1093/acprof:osobl/9780199552917.001.0001 · Cited by 379 · see citing works
Memory for places learned long ago is intact after hippocampal damage
Teng, E., & Squire, L. R. (1999) · Nature · doi:10.1038/23276 · Cited by 372 · see citing works
Thoughts, behaviour, and brain dynamics during navigation in the real world
Spiers, H. J., & Maguire, E. A. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.01.037 · Cited by 371 · see citing works
Self-citationHippocampal theta sequences reflect current goals
Wikenheiser, A. M., & Redish, A. D. (2015) · Nature Neuroscience · doi:10.1038/nn.3909 · Cited by 367 · see citing works
Do Animals Have Cognitive Maps?
Bennett, A. T. D. (1996) · Journal of Experimental Biology · doi:10.1242/jeb.199.1.219 · Cited by 352 · see citing works
Navigation around London by a taxi driver with bilateral hippocampal lesions
Maguire, E. A., Nannery, R., & Spiers, H. J. (2006) · Brain · doi:10.1093/brain/awl286 · Cited by 335 · see citing works
Self-citationSpiers, H. J. (2001) · Brain · doi:10.1093/brain/124.12.2476 · Cited by 329 · see citing works
Self-citationSpatial Memory in the Rat Requires the Dorsolateral Band of the Entorhinal Cortex
Steffenach, H.-A., Witter, M. P., Moser, M., & Moser, E. I. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.044 · Cited by 321 · see citing works
The Neurobiology of the Prefrontal Cortex: Anatomy, Evolution, and the Origin of Insight
Passingham, R. E., & Wise, S. P. (2012) · Cited by 307 · see citing works
Howard, L. R., Javadi, A. H., Yu, Y., Mill, R. D., Morrison, L. C., Knight, R., Loftus, M. M., Staskute, L., & Spiers, H. J. (2014) · Current Biology · doi:10.1016/j.cub.2014.05.001 · Cited by 298 · see citing works
Self-citationBoulougouris, V., Dalley, J. W., & Robbins, T. W. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.02.005 · Cited by 297 · see citing works
Remote spatial memory in an amnesic person with extensive bilateral hippocampal lesions
Rosenbaum, R. S., Priselac, S., Köhler, S., Black, S. E., Gao, F., Nadel, L., & Moscovitch, M. (2000) · Nature Neuroscience · doi:10.1038/79867 · Cited by 293 · see citing works
de Bruin, J. P. C., Sánchez-Santed, F., Heinsbroek, R. P. W., Donker, A., & Postmes, P. (1994) · Brain Research · doi:10.1016/0006-8993(94)90243-7 · Cited by 285 · see citing works
Wolbers, T., Wiener, J. M., Mallot, H. A., & Büchel, C. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2146-07.2007 · Cited by 278 · see citing works
Coding for spatial goals in the prelimbic/infralimbic area of the rat frontal cortex
Hok, V., Save, É., Lenck‐Santini, P., & Poucet, B. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407332102 · Cited by 269 · see citing works
Navigating from hippocampus to parietal cortex
Whitlock, J. R., Sutherland, R. J., Witter, M. P., Moser, M.-B., & Moser, E. I. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804216105 · Cited by 267 · see citing works
Ekstrom, A. D., Arnold, A. E. G. F., & Iaria, G. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00803 · Cited by 263 · see citing works
Rosenbaum, R. S., Ziegler, M., Winocur, G., Grady, C. L., & Moscovitch, M. (2004) · Hippocampus · doi:10.1002/hipo.10218 · Cited by 258 · see citing works
Integrating hippocampus and striatum in decision-making
Johnson, A. C., van der Meer, M. A. A., & Redish, A. D. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.01.003 · Cited by 254 · see citing works
Representation of Spatial Goals in Rat Orbitofrontal Cortex
Feierstein, C. E., Quirk, M. C., Uchida, N., Sosulski, D. L., & Mainen, Z. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.06.032 · Cited by 248 · see citing works
Ferino, F., Thierry, A. M., & Glowinski, J. (1987) · Experimental Brain Research · doi:10.1007/bf00236315 · Cited by 246 · see citing works
Neuronal computations underlying the firing of place cells and their role in navigation
Burgess, N., & O'Keefe, J. M. (1996) · Hippocampus · doi:10.1002/(sici)1098-1063(1996)6:6 · Cited by 240 · see citing works
Fletcher, P. C., Anderson, J. M., Shanks, D. R., Honey, R., Carpenter, T. A., Donovan, T., Papadakis, N., & Bullmore, E. T. (2001) · Nature Neuroscience · doi:10.1038/nn733 · Cited by 238 · see citing works
Involvement of rodent prefrontal cortex subregions in strategy switching.
Ragozzino, M. E., Wilcox, C., Raso, M., & Kesner, R. P. (1999) · Behavioral Neuroscience · doi:10.1037//0735-7044.113.1.32 · Cited by 231 · see citing works
A navigational guidance system in the human brain
Spiers, H. J., & Maguire, E. A. (2007) · Hippocampus · doi:10.1002/hipo.20298 · Cited by 220 · see citing works
Self-citationSpiers, H. J., Burgess, N., Hartley, T., Vargha‐Khadem, F., & O'Keefe, J. M. (2001) · Hippocampus · doi:10.1002/hipo.1087 · Cited by 219 · see citing works
Self-citationThe dynamic nature of cognition during wayfinding
Spiers, H. J., & Maguire, E. A. (2008) · Journal of Environmental Psychology · doi:10.1016/j.jenvp.2008.02.006 · Cited by 218 · see citing works
Self-citationCommon and Distinct Mechanisms of Cognitive Flexibility in Prefrontal Cortex
Kim, C., Johnson, N. F., Cilles, S. E., & Gold, B. T. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5923-10.2011 · Cited by 216 · see citing works
Tracking Route Progression in the Posterior Parietal Cortex
Nitz, D. A. (2006) · Neuron · doi:10.1016/j.neuron.2006.01.037 · Cited by 209 · see citing works
THE FRONTAL LOBE IN MAN: A CLINICAL STUDY OF MAXIMUM REMOVALS
PENFIELD, W., & EVANS, J. (1935) · Brain · doi:10.1093/brain/58.1.115 · Cited by 193 · see citing works
Gilbert, S. J., Frith, C. D., & Burgess, P. W. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03981.x · Cited by 193 · see citing works
Self-citationInformation Processing in Decision-Making Systems
van der Meer, M. A. A., Kurth-Nelson, Z. L., & Redish, A. D. (2012) · The Neuroscientist · doi:10.1177/1073858411435128 · Cited by 186 · see citing works
Cognitive control reflects context monitoring, not motoric stopping, in response inhibition
Chatham, C. H., Claus, E. D., Kim, A., Curran, T., Banich, M. T., & Munakata, Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031546 · Cited by 182 · see citing works
Neural Correlates of Forward Planning in a Spatial Decision Task in Humans
Simon, D. A., & Daw, N. D. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4647-10.2011 · Cited by 181 · see citing works
Steiner, A. P., & Redish, A. D. (2014) · Nature Neuroscience · doi:10.1038/nn.3740 · Cited by 171 · see citing works
Delatour, B., & Gisquet-Verrier, P. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00168-0 · Cited by 170 · see citing works
(2007) · MPG.PuRe (Max Planck Society) · Cited by 169 · see citing works
Hippocampus and retrosplenial cortex combine path integration signals for successful navigation
Sherrill, K. R., Erdem, U. M., Ross, R. S., Brown, T. I., Hasselmo, M. E., & Stern, C. E. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.1825-13.2013 · Cited by 167 · see citing works
Medial prefrontal lesions in the rat and spatial navigation: Evidence for impaired planning.
Granon, S., & Poucet, B. (1995) · Behavioral Neuroscience · doi:10.1037//0735-7044.109.3.474 · Cited by 150 · see citing works
The role of Area 10 (BA10) in human multitasking and in social cognition: A lesion study
Roca, M., Torralva, T., Gleichgerrcht, E. L., Woolgar, A., Thompson, R., Duncan, J., & Manes, F. F. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.09.003 · Cited by 147 · see citing works
Prediction Error during Retrospective Revaluation of Causal Associations in Humans
Corlett, P. R., Aitken, M. R. F., Dickinson, A., Shanks, D. R., Honey, G. D., Honey, R. A. E., Robbins, T. W., Bullmore, E. T., & Fletcher, P. C. (2004) · Neuron · doi:10.1016/j.neuron.2004.11.022 · Cited by 144 · see citing works
Anterior hippocampus and goal-directed spatial decision making
Viard, A., Doeller, C. F., Hartley, T., Bird, C. M., & Burgess, N. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4640-10.2011 · Cited by 144 · see citing works
Place Field Repetition and Purely Local Remapping in a Multicompartment Environment
Spiers, H. J., Hayman, R. M. A., Jovalekic, A., Marozzi, E., & Jeffery, K. J. (2015) · Cerebral Cortex · doi:10.1093/cercor/bht198 · Cited by 138 · see citing works
Self-citationBrown, T. I., Ross, R. S., Keller, J. B., Hasselmo, M. E., & Stern, C. E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6021-09.2010 · Cited by 130 · see citing works
A Goal Direction Signal in the Human Entorhinal/Subicular Region
Chadwick, M. J., Jolly, A., Amos, D. P., Hassabis, D., & Spiers, H. J. (2014) · Current Biology · doi:10.1016/j.cub.2014.11.001 · Cited by 125 · see citing works
Self-citationThe cognitive map as a hippocampus
O'Keefe, J., & Nadel, L. (1979) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00064256 · Cited by 125 · see citing works
Shallice, T., & Cooper, R. (2011) · doi:10.1093/acprof:osobl/9780199579242.001.0001 · Cited by 124 · see citing works
The neuroscience of remote spatial memory: A tale of two cities
Spiers, H. J., & Maguire, E. A. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.06.056 · Cited by 117 · see citing works
Self-citationNeural systems supporting navigation
Spiers, H. J., & Barry, C. (2014) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2014.08.005 · Cited by 117 · see citing works
Self-citationShrager, Y., Kirwan, C. B., & Squire, L. R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805414105 · Cited by 109 · see citing works
Corlett, P. R., Aitken, M. R. F., Dickinson, A., Shanks, D. R., Honey, G. D., Honey, R. A. E., Robbins, T. W., Bullmore, E. T., & Fletcher, P. C. (2004) · Neuron · doi:10.1016/s0896-6273(04)00756-1 · Cited by 98 · see citing works
How the cerebellum may monitor sensory information for spatial representation
Rondi‐Reig, L., Paradis, A., Lefort, J. M., Babayan, B. M., & Tobin, C. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00205 · Cited by 97 · see citing works
A Model of Prefrontal Cortical Mechanisms for Goal-directed Behavior
Hasselmo, M. E. (2005) · Journal of Cognitive Neuroscience · doi:10.1162/0898929054475190 · Cited by 95 · see citing works
Calton, J. L., & Taube, J. S. (2008) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2008.09.015 · Cited by 93 · see citing works
Path integration following temporal lobectomy in humans
Worsley, C. L. (2001) · Neuropsychologia · doi:10.1016/s0028-3932(00)00140-8 · Cited by 86 · see citing works
Linear Look-Ahead in Conjunctive Cells: An Entorhinal Mechanism for Vector-Based Navigation
Kubie, J. L., & Fenton, A. A. (2012) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00020 · Cited by 84 · see citing works
Ventral striatum: a critical look at models of learning and evaluation
van der Meer, M. A. A., & Redish, A. D. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.02.011 · Cited by 84 · see citing works
Partially segregated neural networks for spatial and contextual memory in virtual navigation
Rauchs, G., Orban, P., Balteau, E., Schmidt, C., Degueldre, C., Luxen, A., Maquet, P., & Peigneux, P. (2008) · Hippocampus · doi:10.1002/hipo.20411 · Cited by 83 · see citing works
Contrasting effects on path integration after hippocampal damage in humans and rats
Kim, S., Sapiurka, M., Clark, R. E., & Squire, L. R. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300869110 · Cited by 83 · see citing works
Local remapping of place cell firing in the Tolman detour task
Alvernhe, A., Save, É., & Poucet, B. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07653.x · Cited by 82 · see citing works
Ciaramelli, E. (2007) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2007.11.029 · Cited by 79 · see citing works
Spatial Learning and Action Planning in a Prefrontal Cortical Network Model
Martinet, L., Sheynikhovich, D., Benchenane, K., & Arleo, A. (2011) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002045 · Cited by 79 · see citing works
Different CA1 and CA3 Representations of Novel Routes in a Shortcut Situation
Alvernhe, A., Cauter, T. V., Save, É., & Poucet, B. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1909-08.2008 · Cited by 77 · see citing works
Brown, T. I., & Stern, C. E. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht041 · Cited by 76 · see citing works
Route planning in cats, in relation to the visibility of the goal
Poucet, B., Thinus‐Blanc, C., & Chapuis, N. (1983) · Animal Behaviour · doi:10.1016/s0003-3472(83)80083-9 · Cited by 69 · see citing works
Forward and Backward Inference in Spatial Cognition
Penny, W. D., Zeidman, P., & Burgess, N. (2013) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003383 · Cited by 67 · see citing works
Horizontal biases in rats’ use of three-dimensional space
Jovalekic, A., Hayman, R. M. A., Bécares, N., Reid, H., Thomas, G. E. C., Wilson, J. J., & Jeffery, K. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.02.035 · Cited by 64 · see citing works
Dahmani, L., & Bohbot, V. D. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.07.002 · Cited by 63 · see citing works
Grid Cells, Place Cells, and Geodesic Generalization for Spatial Reinforcement Learning
Gustafson, N. J., & Daw, N. D. (2011) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002235 · Cited by 62 · see citing works
Persistent posterior and transient anterior medial temporal lobe activity during navigation
Xu, J., Evensmoen, H. R., Lehn, H., Pintzka, C. W. S., & Haberg, A. K. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.05.074 · Cited by 59 · see citing works
Gilbert, P. E. (2003) · Neurobiology of Learning and Memory · doi:10.1016/s1074-7427(03)00069-8 · Cited by 59 · see citing works
Rosenbaum, R. S., Winocur, G., Grady, C. L., Ziegler, M., & Moscovitch, M. (2007) · Hippocampus · doi:10.1002/hipo.20354 · Cited by 58 · see citing works
Keeping the goal in mind: Prefrontal contributions to spatial navigation
Spiers, H. J. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2008.01.028 · Cited by 56 · see citing works
Self-citationStimulus and response conflict processing during perceptual decision making
Wendelken, C., Ditterich, J., Bunge, S. A., & Carter, C. S. (2009) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/cabn.9.4.434 · Cited by 54 · see citing works
Heading‐vector navigation based on head‐direction cells and path integration
Kubie, J. L., & Fenton, A. A. (2008) · Hippocampus · doi:10.1002/hipo.20532 · Cited by 49 · see citing works
Winocur, G., Moscovitch, M., Rosenbaum, R. S., & Sekeres, M. (2010) · Hippocampus · doi:10.1002/hipo.20721 · Cited by 49 · see citing works
Contribution of Subregions of Human Frontal Cortex to Novelty Processing
Løvstad, M., Funderud, I., Lindgren, M. P., Endestad, T., Due‐Tønnessen, P., Meling, T. R., Voytek, B., Knight, R. T., & Solbakk, A. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00099 · Cited by 46 · see citing works
The Scale of Functional Specialization within Human Prefrontal Cortex: Figure 1.
Gilbert, S. J., Henson, R. N., & Simons, J. S. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3220-09.2010 · Cited by 45 · see citing works
Self-citationIaria, G., Fox, C. J., Chen, J., Petrides, M., & Barton, J. J. S. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06060.x · Cited by 44 · see citing works
The role of exploratory experience in a shortcut task by golden hamsters (Mesocricetus auratus)
Chapuis, N., Durup, M., & Thinus‐Blanc, C. (1987) · Animal Learning & Behavior · doi:10.3758/bf03204960 · Cited by 36 · see citing works
Differential neural network configuration during human path integration
Arnold, A. E. G. F., Burles, F., Bray, S., Levy, R., & Iaria, G. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00263 · Cited by 34 · see citing works
The hippocampo-cortical loop: Spatio-temporal learning and goal-oriented planning in navigation
Hirel, J., Gaussier, P., Quoy, M., Banquet, J. P., Save, É., & Poucet, B. (2013) · Neural Networks · doi:10.1016/j.neunet.2013.01.023 · Cited by 33 · see citing works
What has functional neuroimaging told us about the organization of mind?
Coltheart, M. (2011) · Cognitive Neuropsychology · doi:10.1080/02643294.2012.666964 · Cited by 31 · see citing works
Muir, G. M., & Taube, J. S. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.12.007 · Cited by 30 · see citing works
Patterns of preserved and impaired spatial memory in a case of developmental amnesia
Rosenbaum, R. S., Cassidy, B. N., & Herdman, K. A. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00196 · Cited by 27 · see citing works
Detour and Shortcut Abilities in Several Species of Mammals
Chapuis, N. (1987) · Springer eBooks · doi:10.1007/978-94-009-3531-0_7 · Cited by 21 · see citing works
Howard, L. R., Kumaran, D., Ólafsdóttir, H. F., & Spiers, H. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067988 · Cited by 16 · see citing works
Self-citationSpiers, H. J. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-375000-6.00190-7 · Cited by 9 · see citing works
Self-citationA local anchor for the brain's compass
Chadwick, M. J., & Spiers, H. J. (2014) · Nature Neuroscience · doi:10.1038/nn.3841 · Cited by 6 · see citing works
Self-citationNitz, D. A. (2014) · Springer eBooks · doi:10.1007/978-3-7091-1292-2_2 · Cited by 4 · see citing works
Cortico-hippocampal communication by way of parallel parahippocampal-subicular pathways.
Lavenex (2000) · Pure Amsterdam UMC · doi:10.1002/1098-1063(2000)10:4 · Cited by 1 · see citing works
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- Shallice T. Cooper R. P. (2011). The Organization of Mind. Oxford: OUP.
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The cognitive map in humans: spatial navigation and beyond
Epstein, R. A., Patai, E. Z., Julian, J. B., & Spiers, H. J. (2017) · Nature Neuroscience · doi:10.1038/nn.4656 · Cited by 921 · see citing works
Self-citationRedish, A. D. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2015.30 · Cited by 462 · see citing works
The successor representation in human reinforcement learning
Momennejad, I., Russek, E. M., Cheong, J. H., Botvinick, M., Daw, N. D., & Gershman, S. J. (2017) · Nature Human Behaviour · doi:10.1038/s41562-017-0180-8 · Cited by 384 · see citing works
Predictive representations can link model-based reinforcement learning to model-free mechanisms
Russek, E. M., Momennejad, I., Botvinick, M., Gershman, S. J., & Daw, N. D. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005768 · Cited by 321 · see citing works
Prospective representation of navigational goals in the human hippocampus
Brown, T. I., Carr, V. A., LaRocque, K. F., Favila, S. E., Gordon, A. M., Bowles, B., Bailenson, J. N., & Wagner, A. D. (2016) · Science · doi:10.1126/science.aaf0784 · Cited by 233 · see citing works
Hippocampal and prefrontal processing of network topology to simulate the future
Javadi, A.-H., Emo, B., Howard, L. R., Zisch, F. E., Yu, Y., Knight, R., Pinelo Silva, J., & Spiers, H. J. (2017) · Nature Communications · doi:10.1038/ncomms14652 · Cited by 207 · see citing works
Self-citationEkstrom, A. D., Huffman, D. J., & Starrett, M. (2017) · Journal of Neurophysiology · doi:10.1152/jn.00531.2017 · Cited by 186 · see citing works
The Versatile Wayfinder: Prefrontal Contributions to Spatial Navigation
Patai, E. Z., & Spiers, H. J. (2021) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2021.02.010 · Cited by 129 · see citing works
Self-citationPredictive maps in rats and humans for spatial navigation
de Cothi, W., Nyberg, N., Griesbauer, E.-M., Ghanamé, C., Zisch, F., Lefort, J. M., Fletcher, L., Newton, C., Renaudineau, S., Bendor, D., et al. (2022) · Current Biology · doi:10.1016/j.cub.2022.06.090 · Cited by 109 · see citing works
Self-citationFrom cognitive maps to spatial schemas
Farzanfar, D., Spiers, H. J., Moscovitch, M., & Rosenbaum, R. S. (2023) · Nature Reviews Neuroscience · doi:10.1038/s41583-022-00655-9 · Cited by 115 · see citing works
Self-citationPredictive Representations in Hippocampal and Prefrontal Hierarchies
Brunec, I. K., & Momennejad, I. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1327-21.2021 · Cited by 116 · see citing works
Brown, T. I., Gagnon, S. A., & Wagner, A. D. (2020) · Current Biology · doi:10.1016/j.cub.2020.03.006 · Cited by 87 · see citing works
Memory integration constructs maps of space, time, and concepts
Morton, N. W., Sherrill, K. R., & Preston, A. R. (2017) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2017.08.007 · Cited by 88 · see citing works
Negrón-Oyarzo, I., Espinosa, N., Aguilar‐Rivera, M., Fuenzalida, M., Aboitiz, F., & Fuentealba, P. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1720117115 · Cited by 86 · see citing works
Spatial Representations in the Human Brain
Herweg, N. A., & Kahana, M. J. (2018) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00297 · Cited by 70 · see citing works
Mobile brain/body imaging of landmark‐based navigation with high‐density EEG
Delaux, A., Aubert, J. D. S., Ramanoël, S., Bécu, M., Gehrke, L., Klug, M., Chavarriaga, R., Sahel, J., Gramann, K., & Arleo, A. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15190 · Cited by 63 · see citing works
Mice learn multi-step routes by memorizing subgoal locations
Shamash, P., Olesen, S. F., Ιορδανίδου, Π., Campagner, D., Banerjee, N., & Branco, T. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00884-8 · Cited by 53 · see citing works
Zheng, L., Gao, Z., McAvan, A. S., Isham, E. A., & Ekstrom, A. D. (2021) · Nature Communications · doi:10.1038/s41467-021-26560-w · Cited by 54 · see citing works
Puthusseryppady, V., Morrissey, S., Spiers, H. J., Patel, M., & Hornberger, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-17634-w · Cited by 54 · see citing works
Self-citationHippocampal place cells encode global location but not connectivity in a complex space
Duvelle, É., Grieves, R. M., Liu, A., Jedidi-Ayoub, S., Holeniewska, J., Harris, A., Nyberg, N., Donnarumma, F., Lefort, J. M., Jeffery, K. J., et al. (2021) · Current Biology · doi:10.1016/j.cub.2021.01.005 · Cited by 48 · see citing works
Self-citationPlanning at decision time and in the background during spatial navigation
Pezzulo, G., Donnarumma, F., Maisto, D., & Stoianov, I. P. (2019) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2019.04.009 · Cited by 44 · see citing works
Functional brain network architecture supporting the learning of social networks in humans
Tompson, S., Kahn, A. E., Falk, E. B., Vettel, J. M., & Bassett, D. S. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2019.116498 · Cited by 43 · see citing works
Neural mechanisms of navigation involving interactions of cortical and subcortical structures
Hinman, J. R., Dannenberg, H., Alexander, A. S., & Hasselmo, M. E. (2018) · Journal of Neurophysiology · doi:10.1152/jn.00498.2017 · Cited by 42 · see citing works
Investigating virtual reality navigation in amnestic mild cognitive impairment using fMRI
Migo, E. M., O’Daly, O., Mitterschiffthaler, M. T., Antonova, E., Dawson, G. R., Dourish, C. T., Craig, K. J., Simmons, A., Wilcock, G. K., McCulloch, E., et al. (2015) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2015.1073218 · Cited by 39 · see citing works
Model-based spatial navigation in the hippocampus-ventral striatum circuit: A computational analysis
Stoianov, I. P., Pennartz, C. M. A., Lansink, C. S., & Pezzulo, G. (2018) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006316 · Cited by 37 · see citing works
Reward-Based Spatial Learning in Teens With Bulimia Nervosa
Cyr, M., Wang, Z., Tau, G. Z., Zhao, G., Friedl, E., Stefan, M., Terranova, K., & Marsh, R. (2016) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2016.07.778 · Cited by 38 · see citing works
Ramanoël, S., York, E. N., Petit, M. L., Lagrené, K., Habas, C., & Arleo, A. (2019) · Frontiers in Neural Circuits · doi:10.3389/fncir.2019.00069 · Cited by 36 · see citing works
Striatal and hippocampal contributions to flexible navigation in rats and humans
Gahnstrom, C. J., & Spiers, H. J. (2020) · Brain and Neuroscience Advances · doi:10.1177/2398212820979772 · Cited by 33 · see citing works
Self-citationThe Impact of Reading Intervention on Brain Responses Underlying Language in Children With Autism
Murdaugh, D. L., Deshpande, H., & Kana, R. K. (2015) · Autism Research · doi:10.1002/aur.1503 · Cited by 35 · see citing works
Javadi, A., Patai, E. Z., Marin-Garcia, E., Margolis, A., Tan, H. M., Kumaran, D., Marko Nardini, A., Penny, W. D., Düzel, E., Dayan, P., et al. (2019) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01414 · Cited by 30 · see citing works
Self-citationSchöberl, F., Zwergal, A., & Brandt, T. (2020) · Frontiers in Neural Circuits · doi:10.3389/fncir.2020.00006 · Cited by 27 · see citing works
Detour Behavior of Mice Trained with Transparent, Semitransparent and Opaque Barriers
Juszczak, G. R., & Miller, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162018 · Cited by 27 · see citing works
Rodent maze studies: from following simple rules to complex map learning
Wijnen, K. V., Genzel, L., & van der Meij, J. (2024) · Brain Structure and Function · doi:10.1007/s00429-024-02771-x · Cited by 27 · see citing works
Visualization of Information Retrieval in Smart Library Based on Virtual Reality Technology
Fang, S. (2020) · Complexity · doi:10.1155/2020/6646673 · Cited by 23 · see citing works
RetractedSheen, J., Chen, Y.-C. D., Hsu, M., Tain, Y., Yu, H., & Huang, L. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00167 · Cited by 22 · see citing works
Baragli, P., Vitale, V., Sighieri, C., Lanatà, A., Palagi, E., & Reddon, A. R. (2017) · Scientific Reports · doi:10.1038/s41598-017-16729-z · Cited by 22 · see citing works
Neural network based successor representations to form cognitive maps of space and language
Stoewer, P., Schlieker, C., Schilling, A., Metzner, C., Maier, A., & Krauß, P. (2022) · Scientific Reports · doi:10.1038/s41598-022-14916-1 · Cited by 21 · see citing works
Gaussier, P., Banquet, J. P., Cuperlier, N., Quoy, M., Aubin, L., Jacob, P.-Y., Sargolini, F., Save, É., Krichmar, J. L., & Poucet, B. (2019) · Journal of Experimental Biology · doi:10.1242/jeb.186932 · Cited by 19 · see citing works
Piccardi, L., Palmiero, M., Cofini, V., Verde, P., Boccia, M., Palermo, L., Guariglia, C., & Nori, R. (2022) · PLoS ONE · doi:10.1371/journal.pone.0271334 · Cited by 16 · see citing works
Mice identify subgoal locations through an action-driven mapping process
Shamash, P., Lee, S., Saxe, A., & Branco, T. (2023) · Neuron · doi:10.1016/j.neuron.2023.03.034 · Cited by 13 · see citing works
Models of spatial and temporal dimensions of memory
Hasselmo, M. E., Hinman, J. R., Dannenberg, H., & Stern, C. E. (2017) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2017.05.024 · Cited by 18 · see citing works
Does spatial cognitive style affect how navigational strategy is planned?
Bocchi, A., Palmiero, M., Nori, R., Verde, P., & Piccardi, L. (2019) · Experimental Brain Research · doi:10.1007/s00221-019-05609-9 · Cited by 16 · see citing works
Predicting real-world navigation performance from a virtual navigation task in older adults
Goodroe, S. C., Velasco, P. F., Gahnstrom, C. J., Wiener, J. M., Coutrot, A., Hornberger, M., & Spiers, H. J. (2025) · PLoS ONE · doi:10.1371/journal.pone.0317026 · Cited by 14 · see citing works
Self-citationA Bio-Inspired Goal-Directed Visual Navigation Model for Aerial Mobile Robots
Mao, J., Hu, X., Zhang, L., He, X., & Milford, M. J. (2020) · Journal of Intelligent & Robotic Systems · doi:10.1007/s10846-020-01190-4 · Cited by 12 · see citing works
Maxim, P., & Brown, T. I. (2021) · Topics in Cognitive Science · doi:10.1111/tops.12576 · Cited by 12 · see citing works
Lithfous, S., Dufour, A., Bouix, C., Pébayle, T., & Després, O. (2017) · Neuropsychology · doi:10.1037/neu0000392 · Cited by 12 · see citing works
Hippocampal and Prefrontal Processing of Network Topology to Simulate the Future
(2017) · Conscious Cities Anthology · doi:10.33797/cca17.01.12 · Cited by 12 · see citing works
Pastor, A., & Bourdin, P. (2024) · Scientific Reports · doi:10.1038/s41598-024-57668-w · Cited by 10 · see citing works
London taxi drivers exploit neighbourhood boundaries for hierarchical route planning
Griesbauer, E., Velasco, P. F., Coutrot, A., Wiener, J. M., Morley, J. G., McNamee, D., Manley, E., & Spiers, H. J. (2024) · Cognition · doi:10.1016/j.cognition.2024.106014 · Cited by 9 · see citing works
Self-citationTravel Planning Ability in Right Brain-Damaged Patients: Two Case Reports
Bocchi, A., Palmiero, M., Boccia, M., Vita, A. D., Guariglia, C., & Piccardi, L. (2020) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2020.00117 · Cited by 8 · see citing works
Threat impairs flexible use of a cognitive map
Silston, B., Ochsner, K. N., & Aly, M. (2023) · Motivation and Emotion · doi:10.1007/s11031-023-10036-z · Cited by 6 · see citing works
Brown, T. I., He, Q., Aselcioglu, I., & Stern, C. E. (2021) · Hippocampus · doi:10.1002/hipo.23365 · Cited by 6 · see citing works
Walking on a minefield: planning, remembering, and avoiding obstacles: preliminary findings
Bocchi, A., Palmiero, M., & Piccardi, L. (2022) · Experimental Brain Research · doi:10.1007/s00221-022-06391-x · Cited by 5 · see citing works
Coding Dynamics of the Striatal Networks During Learning
Villet, M., Reynaud-Bouret, P., Poitreau, J., Baldi, J., Jaffard, S., James, A., Muzy, A., Kartsaki, E., Scarella, G., Sargolini, F., et al. (2024) · eNeuro · doi:10.1523/eneuro.0436-23.2024 · Cited by 5 · see citing works
Mobile brain/body imaging of landmark-based navigation with high-density EEGPreprint
Delaux, A., Aubert, J. D. S., Ramanoël, S., Bécu, M., Gehrke, L., Klug, M., Chavarriaga, R., Sahel, J., Gramann, K., & Arleo, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.13.426330 · Cited by 5 · see citing works
He, Q., Starnes, J., & Brown, T. I. (2022) · Hippocampus · doi:10.1002/hipo.23416 · Cited by 4 · see citing works
Hunter, D., Hazel, S. J., Kind, K. L., Liu, H., Marini, D., Giles, L. C., Blasio, M. J. D., Owens, J. A., Pitcher, J. B., & Gatford, K. L. (2016) · Laterality Asymmetries of Body Brain and Cognition · doi:10.1080/1357650x.2016.1243552 · Cited by 4 · see citing works
Li, M., Cheng, S., Fan, J., Shang, Z., Wan, H., Yang, L., & Yang, L. (2022) · BMC Zoology · doi:10.1186/s40850-022-00143-8 · Cited by 4 · see citing works
Jeffery, K. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.21077-8 · Cited by 7 · see citing works
Active information sampling in health and disease
Attaallah, B., Petitet, P., & Husain, M. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106197 · Cited by 3 · see citing works
SPACE: A novel digital tool for assessing hippocampal structural integrity in older adults
Minta, K., Colombo, G., Tee, M., Low, M., Grübel, J., Wiener, J. M., Chen, C. P., Hilal, S., & Schinazi, V. R. (2026) · Scientific Reports · doi:10.1038/s41598-026-39628-8 · Cited by 4 · see citing works
Common brain areas in spatial navigation and visuo-spatial planning: A meta-analysis
Pepe, S., von Gal, A., Fabiani, G., & Piccardi, L. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106295 · Cited by 4 · see citing works
Individual differences in knowledge network navigation
Zhu, M., Yasseri, T., & Kertész, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-58305-2 · Cited by 3 · see citing works
Postma, A., Bulk, L., Hermens, F., Vogel, M., & Oudman, E. (2025) · Applied Sciences · doi:10.3390/app15084172 · Cited by 2 · see citing works
Do men and women navigate differently in virtual environments? A comparative study
Tang, P., Liao, Y., Zheng, K., Sheng, Y.-F., Ren, W.-J., Liu, C., & Li, Y. (2025) · Int. J. Hum. Comput. Stud. · doi:10.1016/j.ijhcs.2025.103621 · Cited by 3 · see citing works
The hippocampus rapidly integrates sequence representations during novel multistep predictions
Tarder-Stoll, H., Baldassano, C. A., & Aly, M. (2026) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2025.0237 · Cited by 2 · see citing works
Maxim, P., & Brown, T. I. (2026) · NeuroImage · doi:10.1016/j.neuroimage.2026.121736 · Cited by 2 · see citing works
Integration of Euclidean and path distances in hippocampal maps
Ottink, L., de Haas, N., & Doeller, C. F. (2025) · Scientific Reports · doi:10.1038/s41598-025-90504-3 · Cited by 2 · see citing works
Normal Alert Consciousness: A Central Executive Model of Hippocampal Function
Burman, D. D. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.111569 · Cited by 3 · see citing works
Modeling the interaction of learning systems in a reward-based virtual navigation task
Raiesdana, S. (2017) · Journal of Integrative Neuroscience · doi:10.3233/jin-170036 · Cited by 4 · see citing works
Javadi, A., Patai, E. Z., Margois, A., Tan, H. M., Kumaran, D., Marko Nardini, A., Penny, W. D., Düzel, E., Dayan, P., & Spiers, H. J. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/301697 · Cited by 2 · see citing works
Self-citationFunctional brain network architecture supporting the learning of social networks in humansPreprint
Tompson, S., Kahn, A. E., Falk, E. B., Vettel, J. M., & Bassett, D. S. (2019) · doi:10.31234/osf.io/r46gj · Cited by 2 · see citing works
SPACE: A Novel Digital Tool for Assessing Hippocampal Structural Integrity in Older AdultsPreprint
Minta, K., Colombo, G., Tee, M., Low, M., Grübel, J., Wiener, J. M., Chen, C., Hilal, S., & Schinazi, V. R. (2024) · Research Square · doi:10.21203/rs.3.rs-5484040/v1 · Cited by 2 · see citing works
Russi, G. D., Lanzoni, M., Castaldelli, G., Bertolucci, C., Bisazza, A., & Lucon‐Xiccato, T. (2026) · Animal Cognition · doi:10.1007/s10071-026-02056-2 · Cited by 1 · see citing works
Han, D., Qin, T., Yang, T., Liao, H., Hei, Q., Yu, F., Si, B., & Dong, W. (2025) · Geo-spatial Information Science · doi:10.1080/10095020.2025.2541878 · Cited by 1 · see citing works
Patrono, E., Černotová, D., Svoboda, J., & Stuchlı́k, A. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.09.001 · Cited by 1 · see citing works
Development of adaptive motor control for tactile navigationPreprint
Azarfar, A., & Celikel, T. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/762443 · Cited by 1 · see citing works
Tartaglia, E. M., Boucly, C. J., Tatur, G., & Arleo, A. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/481788
Murray, E. A., Wise, S. P., Baldwin, M. K. L., & Graham, K. S. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198828051.003.0004
Editorial overview: Understanding memory: which level of analysis?
Barense, M. D., & Spiers, H. J. (2020) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2020.05.003
Self-citationJavadi, A., Patai, E. Z., Marin-Garcia, E., Margois, A., Tan, H. M., Kumaran, D., Marko Nardini, A., Penny, W. D., Düzel, E., Dayan, P., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/362319
Self-citationAn Examination of the Influence of Landmarks in Human Spatial Navigation Using a Virtual Water Maze
Thornberry, C. (2019) · Maynooth University ePrints and eTheses Archive (Maynooth University)
Tjøstheim, T. A., Johansson, B., & Balkenius, C. (2021) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2021.752219
How Hippocampus Solves Inverse Problems: A Circuit HypothesisPreprint
Arathorn, D. W. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.15.484469
Normal Alert Consciousness - A Central Executive Model of Hippocampal Function
Burman, D. D. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.110108
Maxim, P., He, Q., & Brown, T. I. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-820480-1.00027-9
Patrono, E., Černotová, D., Svoboda, J., & Stuchlı́k, A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.28.601158
Subedi, A., De, S., Cavuoto, L. A., Schwaitzberg, S. D., Hackett, M., & Norfleet, J. (2026) · ACM Transactions on Computing for Healthcare · doi:10.1145/3805808
Prefrontal brain-to-brain synchrony during human group hunting: Evidence from fNIRS hyperscanningPreprint
Yavuz, E., Xu, C., Liu, W., Slinn, C., Mitchell, A., Ali, J., Bloom, N., Khatun, N., Kirk, P. A., Zisch, F., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.05.716331
Self-citationImpact of aging on human decision-making in ecological conditions
Aubert, J. D. S. (2023) · theses.fr (ABES) · doi:10.70675/f7143113zd412z4b5fza432z1032ef6ea209
Hippocampal skill memory expansion drives online performance dynamics during skill learning
Iwane, F., Hayward, W., Karunathilake, I. M. D., Buch, E. R., & Cohen, L. G. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117845
Grabova, D., Kaufmann, E., Pradhan, C., Rémi, J., Vollmar, C., Masouris, I., Wlasich, E., Kustermann, J., Zwergal, A., & Schöberl, F. (2026) · Journal of Neurology · doi:10.1007/s00415-026-14164-7
- Authors
- Spiers, H. J., & Gilbert, S. J.
- Affiliations
- University College London (GB)
- Corresponding author
- Spiers, Hugo J.
- Venue
- Frontiers in Human Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2015-03-20
- Volume
- 9
- Pages
- 125-125
- ISSN
- 1662-5161 (ISSN-L)
- PMC
- PMC4366647
- OpenAlex
- W2016421975
- Cited by
- 94
- References
- 140
- Citations by year
- 2026: 8 · 2025: 8 · 2024: 8 · 2023: 6 · 2022: 9 · 2021: 10 · 2020: 8 · 2019: 9 · 2018: 8 · 2017: 12 · 2016: 6 · 2015: 2
- FWCI
- 0.93
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Human Neuroscience (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- James S. McDonnell Foundation
- Wellcome Trust
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Physical Sciences › Engineering › Automotive Engineering › Spatial Cognition and Navigation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- spatial navigation, prefrontal cortex, hippocampus, prediction error, route planning, path distance, cognitive flexibility
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