Loneliness before and during the COVID-19 pandemic: A systematic review with meta-analysis.
Open accessPublished version of a preprint
Abstract
The COVID-19 pandemic and measures aimed at its mitigation, such as physical distancing, have been discussed as risk factors for loneliness, which increases the risk of premature mortality and mental and physical health conditions. To ascertain whether loneliness has increased since the start of the pandemic, this study aimed to narratively and statistically synthesize relevant high-quality primary studies. This systematic review with meta-analysis was registered at PROSPERO (ID CRD42021246771). Searched databases were PubMed, PsycINFO, Cochrane Library/Central Register of Controlled Trials/EMBASE/CINAHL, Web of Science, the World Health Organization (WHO) COVID-19 database, supplemented by Google Scholar and citation searching (cutoff date of the systematic search December 5, 2021). Summary data from prospective research including loneliness assessments before and during the pandemic were extracted. Of 6,850 retrieved records, 34 studies (23 longitudinal, 9 pseudolongitudinal, 2 reporting both designs) on 215,026 participants were included. Risk of bias (RoB) was estimated using the risk of bias in non-randomised studies-of interventions (ROBINS-I) tool. Standardized mean differences (SMD, Hedges' g) for continuous loneliness values and logOR for loneliness prevalence rates were calculated as pooled effect size estimators in random-effects meta-analyses. Pooling studies with longitudinal designs only (overall N = 45,734), loneliness scores (19 studies, SMD = 0.27 [95% confidence interval = 0.14-0.40], Z = 4.02, p < .001, I 2 = 98%) and prevalence rates (8 studies, logOR = 0.33 [0.04-0.62], Z = 2.25, p = .02, I 2 = 96%) increased relative to prepandemic times with small effect sizes. Results were robust with respect to studies' overall RoB, pseudolongitudinal designs, timing of prepandemic assessments, and clinical populations. The heterogeneity of effects indicates a need to further investigate risk and protective factors as the pandemic progresses to inform targeted interventions. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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Claims the paper makes
0 of 39 cited sources checked · 0 supported · 0 flagged
- Findingcitation
Women were more likely than men to report increases in loneliness.
“Women were more likely to report increases in loneliness than men (Entringer & Gosling, 2021; Entringer et al., 2020; Niedzwiedz et al., 2021; Philpot et al., 2021; Wong et al., 2020)”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites Entringer & Gosling, 2021
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- cites Entringer et al., 2020
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- cites Niedzwiedz et al., 2021
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- Findingcitation
Living alone and/or being single during the pandemic was associated with higher risk of increased loneliness.
“Those who lived alone (Bartrés-Faz et al., 2021; Heidinger & Richter, 2020; Huxhold & Tesch-Römer, 2021; McGrath et al., 2021; Okely et al., 2020; Stolz et al., 2021; Wong et al., 2020) and/or were single during the pandemic (Huxhold & Tesch-Römer, 2021; Stone, 2020) were particularly at risk for higher levels of loneliness compared to pre-pandemic assessments”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Bartrés-Faz et al., 2021
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- cites Heidinger & Richter, 2020
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- cites Huxhold & Tesch-Römer, 2021
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- Findingown data
The meta-analysis's overall pooled effect size was small.
“Furthermore, the overall pooled effect in this study was small and the effect sizes reported by the individual studies were heterogeneous.”
Quote in the paperSubstantial claim - Findingown data
Less than one third of the variance observed was explained by the meta-regression.
“However, the fact that the meta-regression accounted for less than a third of observed variance suggests that other factors may influence the different trajectories of loneliness in the pandemic context.”
Quote in the paperSubstantial claim - Findingown data
The main findings were robust across sensitivity analyses including studies with serious risk of bias, clinical populations, pseudo-longitudinal designs, and overlapping pre-pandemic assessments.
“The main findings of the longitudinal studies were robust against results from 14 studies with serious RoB (SMD = 0.41 [95% CI: 0.11–0.71])”
- Also stated in: § Sensitivity analyses · plain
“two studies with clinical populations (SMD = 0.26 [95% CI: 0.12–0.40]), six studies with pseudo-longitudinal designs (SMD = 0.30 [95% CI: 0.17–0.42]), and two studies whose pre-pandemic assessment period overlapped with the pre-specified date cut-offs (SMD = 0.27 [95% CI: 0.14–0.39])”
Quote in the paperSubstantial claim - Also stated in: § Sensitivity analyses · plain
- Findingown data
In the meta-regression, higher study risk of bias was associated with smaller observed effect sizes.
“This mirrors findings of the meta-regression, in which studies’ higher RoB was negatively associated with the observed effect sizes.”
Quote in the paperSubstantial claim - Findingown data
During-pandemic continuous loneliness scores were higher than pre-pandemic scores (SMD = 0.27, 95% CI 0.14-0.40).
“The during-pandemic assessments yielded higher continuous loneliness scores than the pre-pandemic assessments (SMD = 0.27 [95% CI: 0.14–0.40])”
- Also stated in: § Abstract · plain
“loneliness scores (19 studies, SMD=0.27 [95% confidence interval=0.14–0.40], Z=4.02, p<.001, I2=98%) and prevalence rates (8 studies, logOR=0.33 [0.04–0.62], Z=2.25, p=.02, I2=96%) increased relative to pre-pandemic times with small effect sizes”
Quote in the paperSubstantial claim- Rests on an assumption: Different loneliness measures assess the same underlying construct and can be pooled using standardized mean differences.
- Also stated in: § Abstract · plain
- Findingown data
During-pandemic loneliness prevalence rates were higher than pre-pandemic rates (logOR = 0.33, 95% CI 0.04-0.62).
“and prevalence rates (logOR = 0.33 [95% CI: 0.04–0.62])”
- Also stated in: § Abstract · plain
“prevalence rates (8 studies, logOR=0.33 [0.04–0.62], Z=2.25, p=.02, I2=96%) increased relative to pre-pandemic times with small effect sizes”
Quote in the paperSubstantial claim- Rests on an assumption: Different loneliness measures assess the same underlying construct and can be pooled using standardized mean differences.
- Also stated in: § Abstract · plain
- Findingown data
The most rigorous sensitivity analysis, restricted to longitudinal designs and studies with moderate risk of bias, produced a larger pooled effect than the main analyses.
“Interestingly, the most rigorous analysis (the sensitivity analyses that included only longitudinal study designs and studies with moderate RoB) showed a larger pooled effect size than the main analyses.”
Quote in the paperSubstantial claim - Findingnone given
The duration between loneliness assessments was often reported as a range rather than a concrete number of days or months.
“First, the duration between loneliness assessments was often a range and not a concrete number of days/months.”
Quote in the paperNot a substantial claim - Findingown data
Individual studies' effect sizes were heterogeneous.
“Furthermore, the overall pooled effect in this study was small and the effect sizes reported by the individual studies were heterogeneous.”
Quote in the paperNot a substantial claim - Findingown data
Only overall risk of bias had statistically significant effects in the meta-regression.
“The meta-regression identified age, clinical populations, and studies’ overall RoB as predictors of increases in loneliness, but only overall RoB had statistically significant effects.”
Quote in the paperNot a substantial claim - Findingown data
Longitudinal studies synthesized here point to a rise in loneliness.
“The synthesis of longitudinal studies indicates increases in loneliness.”
Quote in the paperSubstantial claim - Findingnone given
This review included many more primary reports than earlier rapid and systematic reviews.
“The present study synthesized substantially more original reports than previous rapid and systematic reviews.”
Quote in the paperSubstantial claim - Findingnone given
There was little information available about participants' adherence to restrictions.
“There was also little information available regarding participants’ adherence to restrictions.”
Quote in the paperNot a substantial claim - Findingown data
The main analyses included 45,734 participants from four continents.
“Together, these analyses included 45,734 participants from four continents”
Quote in the paperNot a substantial claim - Findingown data
No funnel plot asymmetry was indicated for continuous loneliness scores or prevalence values.
“Neither the rank correlation nor the regression tests indicated any funnel plot asymmetry for the continuous loneliness scores (Z = 0.205, p = .238 and bias = 0.311, p = .756) or prevalence values (Z = 0.236, p = .813 and Kendall’s Tau = 0.286, p = .399)”
Quote in the paperNot a substantial claim - Premisecitation
Social isolation and loneliness are only weakly correlated.
“Some studies have found only weak correlations between social isolation and loneliness (Steptoe et al., 2013; Tanskanen & Anttila, 2016): socially isolated people are not necessarily lonely”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Steptoe et al., 2013
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- cites Tanskanen & Anttila, 2016
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- Interpretationown data
Additional factors may shape how loneliness changed during the pandemic.
“However, the fact that the meta-regression accounted for less than a third of observed variance suggests that other factors may influence the different trajectories of loneliness in the pandemic context.”
Quote in the paperSubstantial claim - Study design and conductown data
A sensitivity analysis confirmed the robustness of results for studies whose pre-pandemic assessment overlapped with the introduced cut-offs.
“However, a sensitivity analysis confirmed the results’ robustness regarding findings of studies whose “pre-pandemic”-assessment overlapped with the introduced cut-offs.”
Quote in the paperNot a substantial claim - Interpretationown data
At this stage, fears of a loneliness pandemic are probably exaggerated.
“However, observed effects were small and heterogeneous, suggesting that at this point in time, concerns about a “loneliness pandemic” are likely overblown.”
Quote in the paperSubstantial claim - Study design and conductreasoning
The design could not establish how particular restrictions affected loneliness.
“Thus, in summary, the study design was not suited to determine effects of (specific) restrictions on loneliness.”
Quote in the paperSubstantial claim - Interpretationown data
The meta-analytic pooled estimate may be lower than the true effect in high-risk groups.
“Taken together, these results suggest that the pooled effect in the present study might underestimate effects in at-risk populations.”
Quote in the paperSubstantial claim - Interpretationreasoning
Heterogeneity of effects might be due to diversity of study characteristics in prior research, including age groups, healthy and clinical populations, regions, designs, and loneliness measures.
“The heterogeneity of effects might stem from the diversity of study characteristics included in prior research (e.g., age groups, healthy and clinical populations, regions, study designs, and loneliness measures).”
Quote in the paperSubstantial claim - Interpretationreasoning
The results may not generalize to groups that do not fit the WEIRD profile.
“As included studies mainly derived from the US and Europe, whereas South America, Asia/Oceania, and Africa were underrepresented, the present findings might not be generalizable to populations not conforming to the WEIRD (Western, educated, industrialized, rich and democratic) stereotype (Henrich et al., 2010).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Henrich et al., 2010
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- Premisecitation
Individuals in conflictual relationships report greater loneliness than those who view their relationships as supportive.
“Research has shown that people in conflictual relationships feel lonelier than those who perceive their relationships as supportive (Hsieh & Hawkley, 2018; Selcuk & Ong, 2013).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Hsieh & Hawkley, 2018
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- cites Selcuk & Ong, 2013
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- Interpretationcitation
The ongoing pandemic and associated restrictions could compromise lonely individuals' efforts to reconnect with others.
“the ongoing pandemic and associated restrictions could compromise lonely individuals’ efforts to reconnect with others (Qualter et al., 2015)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Qualter et al., 2015
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- Premisecitation
According to Masi et al. (2011), the most effective approach was modifying maladaptive social cognitions.
“Further approaches at the individual level might also focus on strategies to modify maladaptive social cognitions (which Masi et al. (2011) found to be the most effective).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Masi et al., 2011
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- Study design and conductreasoning
Certain variables had to be entered into the analyses in simplified forms that did not capture the full complexity of the original designs or changing situations.
“Further, some variables could only be included in the analyses in ways that reduced the complexity of original study designs/dynamic situations:”
Quote in the paperNot a substantial claim - Premisecitation
Two other available reviews did not use meta-regression to examine characteristics linked to loneliness changes.
“While neither of two other available reviews conducted a meta-regression to explore characteristics associated with changes in loneliness (Buecker & Horstmann, 2021; Prati & Mancini, 2021)”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Buecker & Horstmann, 2021
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- cites Prati & Mancini, 2021
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- Study design and conductown data
The findings remained robust in sensitivity analyses that accounted for studies' overall risk of bias.
“Although sensitivity analyses supported the results’ robustness with respect to studies’ overall risk of bias, the meta-regression suggested that it could have led to an underestimation of the magnitude of changes in loneliness.”
Quote in the paperNot a substantial claim - Study design and conductown data
Risk-of-bias assessments showed that most original reports had serious risk of bias in at least one domain, for example measurement of loneliness using untested single items or adaptations of questionnaires intended for other constructs.
“Risk of bias assessments revealed that most original reports had a serious risk of bias in at least one domain, e.g., regarding the measurement of loneliness (including the use of untested single items or adaptations of questionnaires originally intended to measure other constructs).”
Quote in the paperSubstantial claim - Study design and conductreasoning
The meta-regression analysis might have been underpowered because not all predictors of interest could be tested simultaneously.
“However, the analysis might have been underpowered as it was not possible to test all predictors of interest simultaneously.”
Quote in the paperNot a substantial claim - Interpretationreasoning
The primary studies may have left out certain populations-for example, immigrants who do not speak the national language, people with mental or physical disabilities, and those lacking regular internet access-when conducted online.
“Further, the original investigations might have omitted specific groups, such as immigrants not speaking the country’s official language, people with mental and/or physical disabilities, and those without regular internet access, if conducted online.”
Quote in the paperNot a substantial claim - Interpretationown data
The meta-regression suggested that risk of bias could have led to underestimation of the magnitude of changes in loneliness.
“Although sensitivity analyses supported the results’ robustness with respect to studies’ overall risk of bias, the meta-regression suggested that it could have led to an underestimation of the magnitude of changes in loneliness.”
Quote in the paperNot a substantial claim
- May combine two claims. 23
- Classified as probably not a substantial claim. 18
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Findingown data34 studies on 215,026 participants were included.
“In total, 34 articles met the eligibility criteria”
- Also stated in: § Study Characteristics of Included Studies · plain
“Table 1 provides a summary of the main information extracted from the 34 eligible articles, totaling 215,026 participants”
Quote in the paperSubstantial claim- Also stated in: § Study Characteristics of Included Studies · plain
May combine two claims.
Findingown dataOf studies reporting pre- and during-pandemic comparisons, 18 reported an overall increase, 8 reported no change, and 1 reported a decrease.
“Of the studies reporting comparisons of loneliness pre- and during-pandemic, only one reported an overall decrease, 18 reported an overall increase, and eight reported no change”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationIncreases in loneliness were found in both younger and older participant groups.
“Increases in loneliness were found both in younger participant groups, such as students (Beutel et al., 2021; Elmer et al., 2020; Entringer & Gosling, 2021; Rogers et al., 2021) and in older participant groups, such as community cohorts of senior citizens (Heidinger & Richter, 2020; Krendl & Perry, 2021; Wong et al., 2020)”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationStudies showing decreasing loneliness had relied on pre-pandemic assessments shortly before physical distancing, while those with comparison data from months or years before observed increased loneliness.
“Studies showing decreasing loneliness had overwhelmingly relied on pre-pandemic assessments conducted shortly before the implementation of physical distancing, while those with comparison data from months or years before the pandemic had observed increased loneliness during the pandemic”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataAge, clinical population status, and overall risk of bias were identified by the meta-regression as predictors of loneliness increases.
“The meta-regression identified age, clinical populations, and studies’ overall RoB as predictors of increases in loneliness, but only overall RoB had statistically significant effects.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataSome original studies did not report on previously identified vulnerable groups, such as individuals living alone, so these groups could not be tested as predictors.
“As some original studies failed to report on previously identified vulnerable groups (e.g., individuals living alone), these could not be tested as predictors.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataMost studies had a serious overall risk of bias; ten studies had moderate risk of bias.
“Most studies had a serious overall RoB. For ten studies (seven of which were included in the main analyses), RoB was rated as moderate”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThere was a substantial number of studies with high risk of bias due to confounding, while selective reporting bias was rare.
“In summary, there was a substantial number of studies with high RoB due to confounding, whereas bias due to selective reporting of results (including effect estimates) was rare”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIncluded studies mainly came from the US and Europe, while South America, Asia/Oceania, and Africa were underrepresented.
“As included studies mainly derived from the US and Europe, whereas South America, Asia/Oceania, and Africa were underrepresented, the present findings might not be generalizable to populations not conforming to the WEIRD (Western, educated, industrialized, rich and democratic) stereotype (Henrich et al., 2010).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn meta-regression, overall risk of bias was the only significant predictor, with lower risk of bias associated with smaller effect sizes.
“In the final model (21 studies, R2 = .29), overall RoB rating (B = −0.35 [−0.64, −0.07]) was the only significant predictor, indicating that an overall lower RoB was associated with smaller effect sizes”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationLoneliness is linked to factors beyond social isolation, including stable individual traits, environmental factors, physical and mental health, and cultural norms.
“This is because loneliness is related to factors other than social isolation, including temporally stable characteristics of the individual (Mund et al., 2020) and their environment such as personality traits, need for contact and expectations of relationships (Qualter et al., 2015), physical and mental health, and cultural norms (Gierveld et al., 2018; Lim et al., 2020)”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Mund et al., 2020
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- cites Qualter et al., 2015
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- cites Gierveld et al., 2018
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Study design and conductown dataRisk of bias was assessed using ROBINS-I domains, independently rated by two authors, and merged.
“Bias domains included in the ROBINS-I tool (Cochrane Handbook for Systematic Reviews of Interventions version 6.2, 2021, Chapter 25, section 4) were used”
- Also stated in: § Methods for Assessing Risk to Internal Validity/Risk of Bias · plain
“For each study and domain, the RoB was independently rated by two authors as “low”, “moderate” or “serious”. Their assessments were merged”
Quote in the paperNot a substantial claim- Also stated in: § Methods for Assessing Risk to Internal Validity/Risk of Bias · plain
May combine two claims.
PremisecitationLoneliness raises the risk of early death and of mental and physical health problems.
“which increases the risk of premature mortality and mental and physical health conditions”
- Also stated in: § Abstract · plain
“largely due to their serious impact on longevity, mental and physical health, and well-being (Fried et al., 2020; Holt-Lunstad et al., 2015; Leigh-Hunt et al., 2017)”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Fried et al., 2020
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- cites Holt-Lunstad et al., 2015
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- cites Leigh-Hunt et al., 2017
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Study design and conductown dataStudy selection was performed independently by four researchers, discrepancies were resolved by discussion, and eligibility was verified by senior researchers.
“This step was conducted independently by four members of the research group (postdoctoral/senior researchers with previous experience conducting reviews and/or meta-analyses, three psychologists (two full professors) and one medical doctor (assistant professor))”
- Also stated in: § Study Selection · plain
“Discrepancies were resolved through discussion”
- Also stated in: § Study Selection · plain
“Senior researchers (mathematician and medical doctor/psychologist, full professors) verified the eligibility of included studies”
Quote in the paperNot a substantial claim- Also stated in: § Study Selection · plain
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationA more recent systematic review found that longitudinal studies mainly reported increases in loneliness.
“A more recent systematic review, which included neither a meta-analysis nor a meta-regression (Buecker & Horstmann, 2021), found that longitudinal studies mainly reported increases in loneliness”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Buecker & Horstmann, 2021
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PremisecitationStudies have reported stable, increased, and decreased loneliness levels during the pandemic.
“Studies have reported stable (Peng & Roth, 2021; Sibley et al., 2020), as well as increases (Kovacs et al., 2021; Macdonald & Hülür, 2021) and decreases (Bartrés-Faz et al., 2021) in loneliness levels”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Peng & Roth, 2021
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- cites Sibley et al., 2020
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- cites Kovacs et al., 2021
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PremisecitationIt is unclear whether loneliness increased overall after the pandemic began.
“However, it remains unclear whether loneliness has increased overall since the pandemic started (e.g., Killgore et al., 2020; Sutin et al., 2020)”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Killgore et al., 2020
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- cites Sutin et al., 2020
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Study design and conductown dataThe systematic review was registered at PROSPERO before the search was conducted.
“This systematic review with meta-analysis was registered at PROSPERO (ID CRD42021246771)”
- Also stated in: § Abstract · plain
“The study protocol was registered before conducting the search”
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Study design and conductcitationThe latest PRISMA guidelines were followed.
“Throughout the systematic review, the latest PRISMA guidelines were followed (Page et al., 2021)”
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Study design and conductown dataSensitivity analyses were performed to test the robustness of the results.
“To ascertain the results’ robustness, a series of sensitivity analyses were performed (1) including only studies with no ‘serious’ or ‘critical’ overall RoB rating, (2) combining longitudinal and pseudo-longitudinal study designs, (3) incorporating pre-pandemic assessments that overlapped with the date cut-offs specified above, and (4) excluding clinical populations”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationA 2021 systematic review and meta-analysis found no evidence of an increase in loneliness based on three studies.
“A 2021 systematic review and meta-analysis of changes in mental health, focusing on longitudinal studies and natural experiments with pre-pandemic comparisons, found no evidence of increase in loneliness (based on three studies) (Prati & Mancini, 2021)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Prati & Mancini, 2021
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Study design and conductreasoningAn overall risk of bias rating was constructed for sensitivity analyses and meta-regression.
“For use in sensitivity analyses and meta-regression, an overall RoB rating was constructed (≥1 “serious” rating in any domain resulted in a “serious” overall RoB; overall “low” RoB was only present when all domains were rated “low” risk; otherwise, overall risk was considered “moderate”)”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationSustained or chronic loneliness jeopardizes mental and physical health.
“previous research has shown that particularly sustained or chronic loneliness jeopardizes mental and physical health (Cacioppo et al., 2015; National Academies of Science, 2020)”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Cacioppo et al., 2015
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- cites National Academies of Science, 2020
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Study design and conductown dataConfidence in the finding of an increase in loneliness is strengthened by sensitivity analyses, inclusion of high-quality longitudinal research, a large pooled sample, and lack of publication bias.
“The confidence in the finding that there has been an increase in loneliness – albeit small – during the pandemic is strengthened by the results of the sensitivity analyses, the inclusion of only high-quality and longitudinal research in the meta-analyses, the relatively large number of studies with a pooled sample of 45,734 participants, and the lack of any indication of publication bias”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductreasoningWithout control samples that were not exposed to the pandemic, causal inference is weakened, so attributing loneliness increases to the pandemic is harder.
“The lack of control samples unaffected by the pandemic weakens possible causal inference, making it more difficult to attribute the increase in loneliness to the pandemic.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataThe informative value of the meta-regression was hampered by the limited number of predictors that could be tested from available studies, which necessitated a stepwise procedure.
“However, the informative value of the meta-regression was still hampered by the limited number of predictors that could be tested on the basis of the available studies (which also necessitated a stepwise procedure).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationA previous rapid review and meta-analysis reported small increases in mental distress (g = 0.17) based on longitudinal studies.
“A previous rapid review and meta-analysis (Prati & Mancini, 2021) reported small increases in mental distress (overall g = 0.17) based on longitudinal studies”
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PremisecitationThat previous synthesis showed no statistically significant change in loneliness (g = 0.12, p = .34).
“Their synthesis showed no statistically significant change in loneliness (g = 0.12, p = .34)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Prati & Mancini, 2021
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InterpretationcitationThe overall increase in loneliness was small and heterogeneous.
“This constitutes a small (Cohen, 1992; Ferguson, 2009) effect, which was also heterogeneous”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Cohen, 1992
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- cites Ferguson, 2009
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Study design and conductown dataThere was no indication of outliers and none of the studies were overly influential.
“Based on the examination of the studentized residuals, robustness analyses revealed that there was no indication of outliers and according to the Cook’s distances, none of the studies were overly influential”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
PremisecitationThe numerical values of effect size indices often give limited understanding of real-world significance, because even statistically small effects can be highly important.
“The numerical values of effect size indices often provide limited understanding of the real-world significance of those effects, as even statistically small effects can be of high importance (e.g., Meyer et al., 2001).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Meyer et al., 2001
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Study design and conductreasoningRestriction measures were coded from official mandates, but this might have been imprecise if measures differed between regions or if the assessment period spanned changing rules.
“Restriction measures were coded based on official mandates, however, this might have been imprecise if measures differed between regions and/or if the assessment spanned a period in which these rules changed.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductreasoningRegional cut-offs were used to classify assessments as pre-pandemic or during-pandemic, but individuals might also have been affected by restrictions outside their place of residence, such as travel bans.
“Furthermore, as the pandemic progressed differently around the world, we used regional cut-offs to distinguish whether study assessments had taken place before or during the pandemic, but individuals might also have been affected by restrictions outside their place of residence (e.g., travel bans).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationBuecker et al. (2021) reported linear increases in loneliness in emerging adults over recent decades.
“Furthermore, an alternative explanation for increases in loneliness in the population was recently provided by Buecker et al. (2021) who reported linear increases in emerging adults over the last decades.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Buecker et al., 2021
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PremisecitationEarlier work found that social-support interventions, including buddy-care programs, had beneficial effects.
“Previous research has shown positive effects of interventions enhancing social support (such as buddy-care programs) (Masi et al., 2011).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Masi et al., 2011
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PremisecitationPrati and Mancini (2021) used meta-regression to explore predictors of increases in mental health symptoms during the pandemic and found no effects of mean age, gender, or study design.
“Prati and Mancini (2021) explored, using meta-regression, predictors of increases in mental health symptoms during the pandemic. They found no effects of mean age, gender, or study design, either.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Prati & Mancini, 2021
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The paper relies on this without support.
The pandemic and mitigation measures led to fewer social contacts (greater social isolation).
“Since its outbreak, many countries around the world have enacted shelter-in-place and physical distancing orders, travel bans, and switched to remote work and education resulting in fewer social contacts (i.e., greater social isolation), which may in turn have increased loneliness”
The paper relies on this without support.
Different loneliness measures assess the same underlying construct and can be pooled using standardized mean differences.
“For interval- or pseudo-interval-scaled outcomes (continuous loneliness scores), weighted standardized mean differences (Hedges’ g) were used as effect size estimators”
The paper relies on this without support.
Loneliness is a risk factor for premature mortality and for mental and physical health problems.
“However, as loneliness constitutes a risk for premature mortality and mental and physical health, it should be closely monitored, ideally in combination with potential risk and protective factors and health outcomes to derive appropriate interventions.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Social distancing and changes to the quantity and frequency of social interactions due to the pandemic sometimes led to loneliness.
“Previous literature points out that social distancing and changes to the quantity and frequency of social interactions due to the pandemic sometimes led to a significant disruption of social networks (Lampraki et al., 2022) and loneliness (Ernst et al., 2022).”
From Social connections combat loneliness and promote wellbeing among college students coming out of the COVID-19 pandemic (2025) · cites this paper as Ernst et al., 2022
Statistics that don’t add up
Each reported p-value recomputed from its test statistic and degrees of freedom.
Inconsistent p-value: (Z = 0.205, p = .238
MinorThe paper reports p = .238 here; recomputing from the test statistic and its degrees of freedom gives p = .838 (two-tailed). The check cannot tell whether the statistic or the p-value is the misprint.
Reported p = .238 · recomputed p = .838
“(Z = 0.205, p = .238”
Statistics recomputed
Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.
- Doesn’t add upz = 0.205reported p = .238 · recomputed p = .838
“(Z = 0.205, p = .238”
- Consistentz = 4.02reported p < .001 · recomputed p < .001
“Z=4.02, p < .001”
- Consistentz = 2.25reported p = .02 · recomputed p = .024
“Z=2.25, p = .02”
- Consistentz = 0.236reported p = .813 · recomputed p = .813
“(Z = 0.236, p = .813”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Risk-of-bias effect is interpreted in opposite directions
MinorThe results say lower risk of bias was associated with smaller effects, while the discussion says higher risk of bias was associated with smaller effects. The reported negative coefficient, with moderate risk coded 0 and serious risk coded 1, supports the discussion's direction.
“overall RoB rating (B = −0.35 [−0.64, −0.07]) was the only significant predictor, indicating that an overall lower RoB was associated with smaller effect sizes.”
“studies’ higher RoB was negatively associated with the observed effect sizes.”
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How COVID-19 shaped mental health: from infection to pandemic effects
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“However, only some of these systematic reviews and meta-analyses included the prevalence of child and adolescent loneliness (e.g., [15]) and even fewer have focused on loneliness with the well-being of children and adolescents (e.g., [16]).”
BackgroundEducational Research and Innovation
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“Furthermore, the lack of face-to-face interactions resulting from social distancing policies has also increased loneliness in the general population [32].”
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Social isolation and social connectedness among young adult cancer survivors: A systematic review
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“In particular, loneliness has been identified as a factor deeply related to depression and anxiety, showing a significant increase during the pandemic [24].”
Screening for loneliness in representative population samples: Validation of a single-item measure
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“, adapted from questionnaires used to assess different constructs such as depression) hampers the quality and meaningful integration of international, original research [5].”
BackgroundInfluentialSelf-citationLiebmann, M., Pitman, A., Hsueh, Y.-C., Bertotti, M., & Pearce, E. (2022) · BMC Health Services Research · doi:10.1186/s12913-022-08656-1 · Cited by 68 · see citing works
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“With advancements in remote telecommunication, increased opportunities for working from home, and the recent COVID-19 pandemic requiring sheltering in place, U.S. adults have experienced an increased prevalence of loneliness [30,41].”
BackgroundAll the Lonely People: An Integrated Review and Research Agenda on Work and Loneliness
McCarthy, J. M., Erdoğan, B., Bauer, T. N., Kudret, S., & Campion, E. D. (2025) · Journal of Management · doi:10.1177/01492063241313320 · Cited by 70 · see citing works
“In some ways, this is not surprising, as the COVID-19 pandemic ushered in a new era in which loneliness became even more pronounced (Ernst et al., 2022).”
Loneliness in Emerging Adulthood: A Scoping Review
Kirwan, E. M., Burns, A., O’Súilleabháin, P. S., Summerville, S., McGeehan, M., McMahon, J., Gowda, A., & Creaven, A. (2024) · Adolescent Research Review · doi:10.1007/s40894-024-00240-4 · Cited by 69 · see citing works
“One systematic review comparing loneliness before and during the Covid-19 pandemic found an increase in loneliness in younger participant groups (Ernst et al., 2022).”
Bergstedt, J., Pasman, J. A., Ma, Z., Harder, A., Yao, S., Parker, N., Treur, J. L., Smit, D. J. A., Frei, O., Shadrin, A. A., et al. (2024) · Nature Cardiovascular Research · doi:10.1038/s44161-024-00488-y · Cited by 59 · see citing works
“This emphasizes the need for interventions and preventive policies for reducing loneliness in the population, which has further increased in prevalence during the coronavirus disease 2019 pandemic and has been described as a pandemic itself 68,69 .”
Limongi, F., Siviero, P., Trevisan, C., Noale, M., Catalani, F., Ceolin, C., Conti, S., Rosa, E. D., Perdixi, E., Remelli, F., et al. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1166815 · Cited by 51 · see citing works
On social health: history, conceptualization, and population patterning
Doyle, D. M., & Link, B. G. (2024) · Health Psychology Review · doi:10.1080/17437199.2024.2314506 · Cited by 59 · see citing works
“Thorough consideration of each dimension could help guide health policy formation in order to avoid unintended consequences of enacting or prescribing such interventions (e.g., the global rise in loneliness documented after COVID-19; Ernst et al., 2022), which ultimately have important consequences for quality of life.”
Qi, M., Wu, T., Duan, W., & Li, S. (2025) · Behavioral Sciences · doi:10.3390/bs15050696 · Cited by 48 · see citing works
“The failure of employees to establish meaningful social connections with others (e.g., leaders or colleagues) within the organization can result in the emergence of negative emotions, such as loneliness (Ernst et al., 2022; Luhmann et al., 2023; Sullivan & Bendell, 2023).”
Relationship between loneliness and internet addiction: a meta-analysis
Wang, Y., & Zeng, Y. (2024) · BMC Public Health · doi:10.1186/s12889-024-18366-4 · Cited by 58 · see citing works
“Longitudinal studies have shown that loneliness levels increased after the pandemic [83].”
BackgroundHeng, S., & Zhang, Z. (2025) · Psychology Research and Behavior Management · doi:10.2147/prbm.s531805 · Cited by 54 · see citing works
“7,8 During this period, millions turned to CAI for companionship.”
Social connection as a key target for youth mental health
Birrell, L., Werner‐Seidler, A., Davidson, L., Andrews, J. L., & Slade, T. N. (2025) · Mental Health & Prevention · doi:10.1016/j.mhp.2025.200395 · Cited by 43 · see citing works
Kirkland, S., Griffith, L. E., Oz, U. E., Thompson, M. E., Wister, A., Kadowaki, L., Basta, N. E., McMillan, J. M., Wolfson, C. M., Raina, P. S., et al. (2023) · BMC Public Health · doi:10.1186/s12889-023-15807-4 · Cited by 42 · see citing works
“[10] included only longitudinal studies examining loneliness prior to and during the pandemic.”
BackgroundResultTrauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory
Bourassa, K. J., & Sbarra, D. A. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03004-9 · Cited by 40 · see citing works
“…evidence suggests that, at the level of the US population, loneliness increased during the COVID-19 pandemic in relation to pre-pandemic levels [117], and these disturbances in social functioning are hypothesized to play a role in shaping pandemic-related increases in mental health disorder…”
BackgroundLippke, S., & Warner, L. M. (2022) · Applied Psychology Health and Well-Being · doi:10.1111/aphw.12420 · Cited by 39 · see citing works
Schäfer, S. K., Lindner, S., Kunzler, A. M., Meerpohl, J. J., & Lieb, K. (2023) · Age and Ageing · doi:10.1093/ageing/afad170 · Cited by 36 · see citing works
Li, Y., Wang, X., Guo, L., Zhu, L., Shi, J., Wang, W., & Lu, C. (2022) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2022.12.002 · Cited by 35 · see citing works
Holt‐Lunstad, J. (2023) · Policy Insights from the Behavioral and Brain Sciences · doi:10.1177/23727322221150204 · Cited by 36 · see citing works
“With rising trends of social isolation and loneliness (Cigna, 2022; Ernst et al., 2022), the public health consequences may correspondingly increase, without action to reverse this trend.”
BackgroundKleinau, E., Lamba, T., Jaskiewicz, W., Gorentz, K., Hungerbuehler, I., Rahimi, D., Kokota, D., Maliwichi, L., Jamu, E. S., Zumazuma, A., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0303370 · Cited by 43 · see citing works
“27 of the COVID-19 pandemic on loneliness [55].”
Beauchet, O., Matskiv, J., Galéry, K., Goossens, L., Lafontaine, C., & Sawchuk, K. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.969122 · Cited by 33 · see citing works
Qirtas, M. M., Zafeiridi, E., White, E. B., & Pesch, D. (2023) · Digital Health · doi:10.1177/20552076231211104 · Cited by 36 · see citing works
“7 Although they each have their own unique characteristics, loneliness and depression are interrelated conditions that can in fl uence and exacerbate each other.”
BackgroundZhong, B., Yuan, M.-D., Li, F., & Sun, P. (2023) · Psychology Research and Behavior Management · doi:10.2147/prbm.s424565 · Cited by 30 · see citing works
Ip, H., Suen, Y. N., Hui, C. L. M., Cheung, C., Wong, S. M. Y., & Chen, E. Y. H. (2024) · Scientific Reports · doi:10.1038/s41598-024-75739-w · Cited by 31 · see citing works
“The use of diverse forms and variables in different studies has resulted in scattered findings 21 , making it difficult to establish a clear depiction of their predictive validity.”
Schepers, W., Gryp, D., Häussermann, F., Heylen, L., Regenmortel, T. V., & Witte, J. D. (2025) · Health & Place · doi:10.1016/j.healthplace.2025.103491 · Cited by 31 · see citing works
Kleeman, A., Giles‐Corti, B., Gunn, L., Hooper, P., & Foster, S. A. (2022) · Cities · doi:10.1016/j.cities.2022.104126 · Cited by 29 · see citing works
Langenkamp, A. (2023) · Journal of Social and Personal Relationships · doi:10.1177/02654075221144716 · Cited by 27 · see citing works
“Global Meta-Analysis and several European studies show the global scale of the issue (Ernst et al., 2022).”
BackgroundMagis‐Weinberg, L., Vargas, M. A., Carrizales, A., Trinh, C. T., Lopez, D. E. M., Hussong, A. M., & Lansford, J. E. (2024) · Journal of Research on Adolescence · doi:10.1111/jora.12931 · Cited by 31 · see citing works
Sun, H., Zhang, Q., Si, T. L., Bai, W., Chen, P., Lam, M. I., Lok, K.-I., Su, Z., Cheung, T. C. C., Ungvari, G. S., et al. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.115744 · Cited by 25 · see citing works
Briere, J. L., Wang, S. H., Khanam, U., Lawson, J., & Goodridge, D. M. (2023) · BMC Geriatrics · doi:10.1186/s12877-023-04350-x · Cited by 25 · see citing works
“Personal and environmental factors such as personality traits, relationship expectations, physical and mental health, and cultural norms may all contribute to an individual’s perception of loneliness, regardless of the level of social contact [22].”
BackgroundSeewer, N., Skoko, A., Käll, A., Andersson, G., Luhmann, M., Berger, T., & Krieger, T. (2024) · Scientific Reports · doi:10.1038/s41598-024-57254-0 · Cited by 26 · see citing works
“Albeit prevalence rates of loneliness have increased after the beginning of the COVID-19 pandemic 4 , loneliness was even before a prevalent phenomenon.”
BackgroundHausman, H. K., Dai, Y. E., O’Shea, A. M., Dominguez, V. N., Fillingim, M., Calfee, K., Carballo, D., Hernandez, C. M., Perryman, S., Kraft, J. N., et al. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.999107 · Cited by 26 · see citing works
“pre-pandemic timepoints; however, the effects were small and heterogenous (Ernst et al., 2022).”
BackgroundWang, X., Cao, X., Yu, J., Jin, S., Li, S., Chen, L., Liu, Z., Ge, X., & Lu, Y. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-05609-2 · Cited by 27 · see citing works
Wenig, V., Heumann, E., Stock, C., Busse, H., Negash, S., Pischke, C. R., & Heinrichs, K. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1284460 · Cited by 26 · see citing works
“In general, younger age groups were found to be more likely to experience loneliness (6, 7, 9, 21).”
BackgroundUnderstanding loneliness in late life
Huxhold, O., & Fiori, K. L. (2024) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2024.101801 · Cited by 22 · see citing works
Ding, X., Shang, B., & Yu, F. (2022) · Religions · doi:10.3390/rel13111085 · Cited by 22 · see citing works
In-person interventions to reduce social isolation and loneliness: An evidence and gap map
Welch, V. A., Ghogomu, E. T., Dowling, S., Barbeau, V. I., Al‐Zubaidi, A. A. A., Beveridge, E., Bondok, M., Desai, P., Doyle, R., Huang, J. X., et al. (2024) · Campbell Systematic Reviews · doi:10.1002/cl2.1408 · Cited by 24 · see citing works
Self-citationFlesaker, M., Freibott, C. E., Evans, T. C., Gradus, J. L., & Lipson, S. K. (2024) · Journal of American College Health · doi:10.1080/07448481.2024.2400105 · Cited by 23 · see citing works
“37 This is highly relevant to the current study given the timing of data collection (2021–2022).”
Prevalence of Loneliness in Older Adults: A Scoping Review
Schroyen, S., Janssen, N., Duffner, L. A., Veenstra, M. Y., Pyrovolaki, E., Salmon, É., & Adam, S. (2023) · Health & Social Care in the Community · doi:10.1155/2023/7726692 · Cited by 21 · see citing works
“Te increase in loneliness is confrmed across age groups in general meta-analysis as well as the great heterogeneity between studies [46].”
Jafarlou, S., Azimi, I., Lai, J., Wang, Y., Labbaf, S., Nguyen, B., Qureshi, H., Marcotullio, C., Borelli, J. L., Dutt, N. D., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0298949 · Cited by 21 · see citing works
“However, a recent meta-analysis by Ernst and colleagues [18] suggested a small yet significant effect size in the differences between feelings of loneliness before and after the pandemic.”
The Impact of the COVID-19 Pandemic on Adolescents: An Opportunity to Build Resilient Systems
Nadeem, E., & Meter, A. V. (2023) · American Journal of Health Promotion · doi:10.1177/08901171221140641d · Cited by 21 · see citing works
Liu, J., & Lee, J.-S. (2024) · Online Media and Global Communication · doi:10.1515/omgc-2024-0025 · Cited by 20 · see citing works
Massihzadegan, S., & Stokes, J. E. (2023) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbad081 · Cited by 20 · see citing works
Tsiouris, A., Werner, A. M., Tibubos, A. N., Mülder, L. M., Reichel, J. L., Heller, S., Schäfer, M., Schwab, L., Rigotti, T., Stark, B., et al. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1163541 · Cited by 20 · see citing works
Self-citationEmerson, E., Stancliffe, R. J., Aitken, Z., Bailie, J., Bishop, G. M., Badland, H. M., Llewellyn, G. M., & Kavanagh, A. M. (2023) · BMC Public Health · doi:10.1186/s12889-023-17481-y · Cited by 20 · see citing works
“Known risk factors for experiencing loneliness include female gender, younger age, not being married/part-nered, experiencing partner loss, living alone, being unemployed, having limited social networks, low level of social activity, poor self-reported health or mental health difficulties [13–15].”
BackgroundInfluentialJing, J., Dahlberg, L., Canter, D. V., & Plater-Zyberk, E. (2024) · Health & Social Care in the Community · doi:10.1155/2024/4172682 · Cited by 20 · see citing works
“…of public space including third places implemented in many parts of the world were assumingly associated with an increase in loneliness in public discussions, systematic reviews of longitudinal studies reveal a small and heterogeneous increase in loneliness before and during the pandemic [15, 16].”
BackgroundCompassionate AI Design, Governance, and Use
Ciriello, R., Chen, A., & Rubinsztein, Z. (2025) · IEEE Transactions on Technology and Society · doi:10.1109/tts.2025.3538125 · Cited by 19 · see citing works
“Given that loneliness affects one in four people globally and contributes to mental and physical health challenges, these technologies risk intensifying an already critical issue [16], [17], [18], [19].”
The burdens of poverty during the COVID-19 pandemic
Petersen, J., Hettich, N., Baumkötter, R., Wild, P. S., Pfeiffer, N., Münzel, T. F., König, J., Lackner, K. J., & Beutel, M. E. (2022) · Frontiers in Sociology · doi:10.3389/fsoc.2022.995318 · Cited by 19 · see citing works
“Also, multiple studies have identified low income to be a major risk factor for poor mental health outcomes during the pandemic (Daly et al., 2020; Peters et al., 2020; Santabárbara et al., 2020; Breslau et al., 2021; Fancourt et al., 2021; Kunzler et al., 2021; Niedzwiedz et al., 2021; Benatov et al., 2022; Bonati et…”
BackgroundSelf-citationGabarrell‐Pascuet, A., Varga, T. V., Moneta, M. V., Ayuso‐Mateos, J. L., Lara, E., Olaya, B., Haro, J. M., & Domènech‐Abella, J. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.02.042 · Cited by 20 · see citing works
Schütz, R., & Bilz, L. (2023) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s00103-023-03728-x · Cited by 19 · see citing works
“DasThema Einsamkeit ist für die öffentliche Gesundheit und den politischen Diskurs von zunehmender Bedeutung [1].”
BackgroundInfluentialMoayad, L., Zajner, C., Popovic, M. M., Mercer, G., Kertes, P. J., Muni, R. H., Hall, E., Goel, N., Rana, M., & Kohly, R. P. (2023) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2023.06.015 · Cited by 19 · see citing works
Lara, E., Matovic, S., Vasiliadis, H., Grenier, S., Berbiche, D., de la Torre‐Luque, A., & Gouin, J. (2023) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2023.105133 · Cited by 19 · see citing works
Brown, J. K., & Papp, L. M. (2023) · Stress and Health · doi:10.1002/smi.3320 · Cited by 23 · see citing works
Reliability and validity evaluation of the stigma of loneliness scale in Chinese college students
Fan, Z., Shi, X., Yang, S., Sun, Y., & Chen, R. (2024) · BMC Public Health · doi:10.1186/s12889-024-17738-0 · Cited by 23 · see citing works
“Loneliness has become a global public health problem that seriously plagues people of different age groups [3, 4].”
BackgroundGlobal Trends and Disparities in Social Isolation
Fuller‐Rowell, T. E., Sultana, S., & Kawachi, I. I. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2025.32008 · Cited by 20 · see citing works
PROTOCOL: In-person interventions to reduce social isolation and loneliness: An evidence and gap map
Welch, V. A., Ghogomu, E. T., Dowling, S., Barbeau, V. I., Al-Zubaidi, A. A., Beveridge, E., Bondok, M., Desai, P., Doyle, R., Huang, J., et al. (2023) · Campbell Systematic Reviews · doi:10.1002/cl2.1340 · Cited by 19 · see citing works
“Small increases in the prevalence of loneliness were also observed in a recent synthesis of longitudinal studies during the COVID‐19 pandemic (Ernst et al., 2022).”
ResultSelf-citationDahlberg, L., von Saenger, I., Naseer, M., Lennartsson, C., & Agahi, N. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1444990 · Cited by 18 · see citing works
“…and a general lack of nationally representative or well-stratified samples has been noted, studies generally found an increase in loneliness and social isolation in older adults during the COVID-19 pandemic (25–27), especially among studies conducted more than 3 months into the pandemic (17).”
BackgroundSocial Bonds Retain Oxytocin-Mediated Brain-Liver Axis to Retard Atherosclerosis
Ko, S., Anzai, A., Liu, X., Kinouchi, K., Yamanoi, K., Torimitsu, T., Ichihara, G., Kitakata, H., Shirakawa, K., Katsumata, Y., et al. (2024) · Circulation Research · doi:10.1161/circresaha.124.324638 · Cited by 19 · see citing works
“10 Consequently, SI and loneliness emerge as critical determinants of CVD and all-cause mortality.”
The pandemic and social experience: For whom did discrimination and social isolation increase?
Fuller‐Rowell, T. E., Nichols, O. I., El‐Sheikh, M., Burrow, A. L., Ong, A. D., & Ryff, C. D. (2022) · Cultural Diversity & Ethnic Minority Psychology · doi:10.1037/cdp0000561 · Cited by 17 · see citing works
Self-citationKretzler, B., König, H., & Hajek, A. (2022) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2022.104900 · Cited by 18 · see citing works
“, 2022) as well as among the general population (Ernst et al., 2022).”
Ernst, M., Brähler, E., Kruse, J., Kampling, H., & Beutel, M. E. (2023) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2023.100486 · Cited by 19 · see citing works
Self-citationSiddiq, H., Teklehaimanot, S., & Guzman, A. A. (2023) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-023-02549-2 · Cited by 18 · see citing works
Lim, M. H., Hennessey, A., Qualter, P., Smith, B. J., Thurston, L., Eres, R., & Holt‐Lunstad, J. (2024) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-024-02740-z · Cited by 21 · see citing works
Petersen, J., Reinwarth, A. C., Beutel, M. E., Brähler, E., & Decker, O. (2024) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2024.100496 · Cited by 16 · see citing works
“…social relations has increasingly come to the fore-front of research and public health following discussion about psycho-social consequences of the public health measures during the COVID-19 pandemic on mental health (e.g., social isolation and loneliness) (Ernst et al., 2022; Holt-Lunstad, 2021).”
BackgroundInfluentialSelf-citationEngel, L., Rizal, M. F., Clifford, S., Faller, J., Lim, M. H., Le, L. K., Chatterton, M. L., & Mihalopoulos, C. (2025) · PharmacoEconomics · doi:10.1007/s40273-025-01516-w · Cited by 16 · see citing works
“Many public health measures enacted during the pandemic exacerbated feelings of lone-liness and social isolation [8], prompting calls for further investigations into their psychological, social, and economic impacts.”
Bırni, G., Satıcı, S. A., & Deniz, M. E. (2023) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2023.106112 · Cited by 16 · see citing works
What allays loneliness? A fine-grained examination of daily social interactions
Silva, G., Rum, R., Brennan, J., Rottenberg, J. A., & Goodman, F. R. (2023) · Journal of Social and Personal Relationships · doi:10.1177/02654075231181709 · Cited by 16 · see citing works
“Stay-at-home orders coupled with fears of spreading illness disrupted people ’ s socialization and increased rates of loneliness (Ernst et al., 2022).”
BackgroundLuk, J. W., Leiter, N., Stangl, B. L., Gunawan, T., Schwandt, M. L., Goldman, D. A., Diazgranados, N., & Ramchandani, V. A. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.115826 · Cited by 16 · see citing works
Ernst, M., Beutel, M. E., & Brähler, E. (2022) · Scientific Reports · doi:10.1038/s41598-022-06016-x · Cited by 16 · see citing works
Self-citationMatthaeus, H., Godara, M., Silveira, S., Hecht, M., Voelkle, M., & Singer, T. (2024) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph21050570 · Cited by 15 · see citing works
“This rising trend in loneliness, also referred to as a loneliness epidemic [13], has been amplified in recent years by the COVID-19 pandemic [14].”
ResultOpioid Regulation of Social Homeostasis: Connecting Loneliness to Addiction
Løseth, G. E., Eikemo, M., & Leknes, S. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.11.011 · Cited by 16 · see citing works
“Cross-sectional studies reported increased prevalence of loneliness, pain, and substance use during the first years of the pandemic (11– 13).”
What works to reduce loneliness: a rapid systematic review of 101 interventions
Blodgett, J. M., Tiley, K., Harkness, F., & Musella, M. (2025) · Journal of Public Health Policy · doi:10.1057/s41271-025-00561-1 · Cited by 15 · see citing works
“Recent reviews of loneliness interventions have highlighted heterogeneity between studies as a major limitation [68, 69].”
Why friendship and loneliness affect our health
Dunbar, R. (2025) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.15309 · Cited by 16 · see citing works
Broen, T., Choi, Y., Garza, E. Z., Pauly, T., Gerstorf, D., & Hoppmann, C. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.1021863 · Cited by 12 · see citing works
Youth loneliness in pandemic times: a qualitative study in Quebec and Ontario
de Velde, C. V., Boudreault, S., & Berniard, L. (2023) · International Journal of Adolescence and Youth · doi:10.1080/02673843.2023.2223671 · Cited by 15 · see citing works
“…age has emerged as one of the most predictive factors of loneliness: while all age groups have experienced a significant increase in loneliness (Ernst et al., 2022; Kovacs et al., 2021; O’Sullivan et al., 2021), the youngest age groups have experienced the largest increase in the United…”
BackgroundAl‐Sibani, N., Chan, M. F., Al‐Huseini, S., Kharusi, N. A., Guillemin, G. J., Al-Abri, M., Ganesh, A., Hasani, Y. A., & Al‐Adawi, S. (2023) · PLoS ONE · doi:10.1371/journal.pone.0279612 · Cited by 15 · see citing works
A Longitudinal Study on Loneliness during the COVID-19 Pandemic in Japan
Lal, S., Nguyen, T. X. T., Sulemana, A.-S., Yuktadatta, P., Khan, M. S. R., & Kadoya, Y. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191811248 · Cited by 15 · see citing works
“[23] explored whether changes such as lockdowns, physical distancing, and the switch to remote work and school during the pandemic increased people’s loneliness and found that while these measures increased social isolation, they do not always lead to loneliness.”
BackgroundLoneliness, health and applied psychology
Steptoe, A. (2022) · Applied Psychology Health and Well-Being · doi:10.1111/aphw.12417 · Cited by 15 · see citing works
Wollast, R., Lacourse, É., Mageau, G. A., Pelletier-Dumas, M., Dorfman, A., Dupéré, V., Lina, J.-M., Stolle, D., & de la Sablonnière, R. (2023) · PLoS ONE · doi:10.1371/journal.pone.0292522 · Cited by 14 · see citing works
“Based on the pooled effect sizes of 19 studies, Ernst et al. [2] found an overall small increase in loneliness since the start of the pandemic (see also [4] for similar results).”
He, T., Tu, C. C., & Bai, X. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.948214 · Cited by 14 · see citing works
“Loneliness because of COVID-19related isolation and social distancing has negatively affected individuals’ mental health, anxiety, and perceived social support, thus reducing their sense of happiness and increasing their risk of mental health problems; these outcomes of lockdown and quarantining are prevalent, particu…”
BackgroundLee, J., Chang, S. M., Hahm, B., Park, J. E., Seong, S. J., Hong, J. P., Jeon, H. J., An, H., & Kim, B. (2023) · Journal of Korean Medical Science · doi:10.3346/jkms.2023.38.e287 · Cited by 14 · see citing works
Wollast, R., Preece, D. A., Schmitz, M., Bigot, A., Gross, J. J., & Luminet, O. (2023) · Cognition & Emotion · doi:10.1080/02699931.2023.2270201 · Cited by 14 · see citing works
“These fi ndings join others in emphasising the important roles that everyday experiences of loneliness play in shaping global indicators of health and well-being (for a systematic review with meta-analysis, see Ernst et al., 2022).”
BackgroundVilleneuve, P. J., Gill, G. K., Cottagiri, S. A., Dales, R., Rainham, D. G. C., Ross, N. A., Dogan, H., Griffith, L. E., Raina, P. S., & Crouse, D. L. (2023) · Canadian Journal of Public Health · doi:10.17269/s41997-023-00841-x · Cited by 14 · see citing works
“Loneliness has been defined as the perceived difference between desired and achieved connection (Peplau and Perlman 1982; Ernst et al. 2022), but can be understood on a social, emotional (Weiss 1973), and existential basis (Bolmsjo et al. 2019).”
BackgroundShrout, M. R., Wilson, S. J., Farrell, A. K., Rice, T. M., Weiser, D. A., Novak, J. R., & Monk, J. K. (2024) · Social and Personality Psychology Compass · doi:10.1111/spc3.12943 · Cited by 14 · see citing works
Disparities by Social Determinants of Health: Links Between Long COVID and Cardiovascular Disease
Banerjee, A. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.02.017 · Cited by 14 · see citing works
Johnson, K. T., Zawadzki, M. J., & Kho, C. (2024) · Sleep Health · doi:10.1016/j.sleh.2024.04.003 · Cited by 14 · see citing works
“21 Furthermore, poor sleep is common among college students 22-24 and often increases over time.”
Loneliness during the COVID-19 pandemic: Evidence from five European countries
Rebechi, A., Lepinteur, A., Clark, A. E., Rohde, N., Vögele, C., & D’Ambrosio, C. (2024) · Economics & Human Biology · doi:10.1016/j.ehb.2024.101427 · Cited by 15 · see citing works
“Many articles have explored the socio-demographic determinants of loneliness (Bu et al., 2020a, 2020b; Buecker and Horstmann, 2022; Ernst et al., 2022; Groarke et al., 2020; Killgore et al., 2020; Hu and Gutman, 2021; Lampraki et al., 2022; Losada-Baltar et al., 2021; Rumas et al., 2021; Okruszek…”
BackgroundWilding, S., O'Connor, D., Ferguson, E., Wetherall, K., Cleare, S., O'Carroll, R., Robb, K., & O'Connor, R. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114876 · Cited by 21 · see citing works
“It is clear from recent meta-analytical findings that there were small, but robust increases in loneliness during the pandemic (Ernst et al., 2022).”
Beyond Finding Purpose: Motivating a Translational Science of Purpose Acquisition
Burrow, A. L. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20126091 · Cited by 9 · see citing works
Im, J. H. B., Bronskill, S. E., Strauss, R., Gruneir, A., Guan, J., Boblitz, A., Lu, M., Rochon, P. A., & Savage, R. (2023) · Journal of the American Geriatrics Society · doi:10.1111/jgs.18477 · Cited by 13 · see citing works
“52 Although recent estimates of loneliness in older Canadians, which range from 32% to 43%, are comparable to our study, the relationship between lone-liness and polypharmacy could be changing in ways that are not yet clear.”
ResultHerbolsheimer, F., Peters, A., Wagner, S. A., Willich, S. N., Krist, L., Pischon, T., Nimptsch, K., Gastell, S., Brandes, M., Brandes, B., et al. (2024) · BMC Public Health · doi:10.1186/s12889-024-17675-y · Cited by 13 · see citing works
- Authors
- Ernst, M., Niederer, D., Werner, A. M., Czaja, S. J., Mikton, C., Ong, A. D., Rosen, T., Brähler, E., & Beutel, M. E.
- Affiliations
- Johannes Gutenberg University Mainz (DE)
- Goethe University Frankfurt (DE)
- Weill Cornell Medicine (US)
- World Health Organization (CH)
- Cornell University (US)
- NewYork–Presbyterian Hospital (US)
- Corresponding author
- Ernst, Mareike
- ORCID
- Venue
- American Psychologist
- Published
- 2022-07
- Volume
- 77
- Issue
- 5
- Pages
- 660-677
- ISSN
- 0003-066X (ISSN-L)
- 1935-990X
- PMC
- PMC9768682
- OpenAlex
- W4229451984
- Cited by
- 584
- References
- 73
- Citations by year
- 2026: 83 · 2025: 144 · 2024: 172 · 2023: 143 · 2022: 41
- FWCI
- 114.17
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- American Psychologist (publishedVersion, other-oa)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- PsyArXiv (OSF Preprints) (submittedVersion)
- Funders
- Mainz Research Center for Mental Health
- National Institute on Aging (K76 AG054866)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Social Sciences › Health › Health disparities and outcomes
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Keywords
- loneliness, COVID-19 pandemic, social distancing, prevalence of loneliness, pre-pandemic comparison, mental health, social isolation, risk factors for loneliness
- MeSH terms
- COVID-19, Humans, Loneliness, Prospective Studies, Pandemics
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