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MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

Malinin, Nikolai L., Boldin, Mark P., Kovalenko, Andrei V., Wallach, David·1997·Nature

DOI 10.1038/385540a0

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Nidai Ozes, O., Mayo, L. D., Gustin, J. A., Pfeffer, S. R., Pfeffer, L. M., & Donner, D. B. (1999) · Nature · doi:10.1038/43466 · Cited by 1,832
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Kelliher, M. A., Grimm, S., Ishida, Y., Kuo, F., Stanger, B. Z., & Leder, P. (1998) · Immunity · doi:10.1016/s1074-7613(00)80535-x · Cited by 1,102
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Authors: Malinin, N. L., Boldin, M. P., Kovalenko, A. V., & Wallach, D.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1997-02
Volume: 385
Issue: 6616
Pages: 540-544
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/385540a0
OpenAlex: W2067680656
Cited by: 1,280
References: 1
FWCI: 67.37
Type: journal article
Language: en
Open access: closed

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MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

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