Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

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Items 101–145 of 145

  1. AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction
    Turdi, Subat, Fan, Xiujuan, Li, Ji, Zhao, Junxing, Huff, Anna F., Du, Min, Ren, Jun · 2010 · Aging Cell
  2. Activation of AMPK under Hypoxia: Many Roads Leading to Rome
    Dengler, Franziska · 2020 · International Journal of Molecular Sciences
  3. Adipokines as regulators of muscle metabolism and insulin sensitivityThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.
    Dyck, David J. · 2009 · Applied Physiology, Nutrition, and Metabolism
  4. A high-fat diet decreases AMPK activity in multiple tissues in the absence of hyperglycemia or systemic inflammation in rats
    Lindholm, Christopher R., Ertel, Rebecca L., Bauwens, Jake D., Schmuck, Eric G., Mulligan, Jacob D., Saupe, Kurt W. · 2013 · Journal of Physiology and Biochemistry
  5. Obesity, leptin, and Alzheimer's disease
    Lee, Edward B. · 2011 · Annals of the New York Academy of Sciences
  6. The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia
    Mulligan, Kathleen, Khatami, Hootan, Schwarz, Jean-Marc, Sakkas, Giorgos K., DePaoli, Alex M., Tai, Viva W., Wen, Michael J., Lee, Grace A., Grunfeld, Carl, Schambelan, Morris · 2009 · The Journal of Clinical Endocrinology & Metabolism
  7. α1-AMP-Activated Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct Phosphorylation of Protein Kinase Cζ
    Gusarova, Galina A., Dada, Laura A., Kelly, Aileen M., Brodie, Chaya, Witters, Lee A., Chandel, Navdeep S., Sznajder, Jacob I. · 2009 · Molecular and Cellular Biology
  8. Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake
    Olson, David P., Pulinilkunnil, Thomas, Cline, Gary W., Shulman, Gerald I., Lowell, Bradford B. · 2010 · Proceedings of the National Academy of Sciences
  9. Reduced glycogen availability is associated with increased AMPKα2 activity, nuclear AMPKα2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle
    Steinberg, Gregory R, Watt, Matthew J, McGee, Sean L, Chan, Stanley, Hargreaves, Mark, Febbraio, Mark A, Stapleton, David, Kemp, Bruce E · 2006 · Applied Physiology, Nutrition, and Metabolism
  10. Macrophages facilitate resistance to anti-VEGF therapy by altered VEGFR expression
    Dalton, Heather J., Pradeep, Sunila, McGuire, Michael, Hailemichael, Yared, MA, Shaolin, Lyons, Yasmin, Armaiz-Pena, Guillermo N., Previs, Rebecca A., Hansen, Jean Marie, Rupaimoole, Rajesha et al. · 2017 · Clinical Cancer Research
  11. AMP-Activated Protein Kinase Is Not Down-Regulated in Human Skeletal Muscle of Obese Females
    Steinberg, Gregory R., Smith, Angela C., van Denderen, Bryce J. W., Chen, Zhiping, Murthy, Sid, Campbell, Duncan J., Heigenhauser, G. J. F., Dyck, David J., Kemp, Bruce E. · 2004 · The Journal of Clinical Endocrinology & Metabolism
  12. Changes in body composition in patients with severe lipodystrophy after leptin replacement therapy
    Moran, Stephanie Ann, Patten, Nicole, Young, Janice Ryan, Cochran, Elaine, Sebring, Nancy, Reynolds, James, Premkumar, Ahalya, Depaoli, Alex M, Skarulis, Monica C, Oral, Elif Arioglu et al. · 2004 · Metabolism
  13. The discovery of drugs for obesity, the metabolic effects of leptin and variable receptor pharmacology: perspectives from β3-adrenoceptor agonists
    Arch, Jonathan R. S. · 2008 · Naunyn-Schmiedeberg's Archives of Pharmacology
  14. Polyunsaturated Fatty Acids Attenuate Diet Induced Obesity and Insulin Resistance, Modulating Mitochondrial Respiratory Uncoupling in Rat Skeletal Muscle
    Cavaliere, Gina, Trinchese, Giovanna, Bergamo, Paolo, De Filippo, Chiara, Mattace Raso, Giuseppina, Gifuni, Giorgio, Putti, Rosalba, Moni, Bottu Heleena, Canani, Roberto Berni, Meli, Rosaria et al. · 2016 · PLOS ONE
  15. Hypothalamic AMP-Activated Protein Kinase Regulates Glucose Production
    Yang, Clair S., Lam, Carol K.L., Chari, Madhu, Cheung, Grace W.C., Kokorovic, Andrea, Gao, Sun, Leclerc, Isabelle, Rutter, Guy A., Lam, Tony K.T. · 2010 · Diabetes
  16. Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson‐Mendenhall syndrome
    Cochran, Elaine, Young, Janice Ryan, Sebring, Nancy, DePaoli, Alex, Oral, Elif Arioglu, Gorden, Phillip · 2004 · The Journal of Clinical Endocrinology & Metabolism
  17. Type I iodothyronine 5′-deiodinase mRNA and activity is increased in adipose tissue of obese subjects
    Ortega, F J, Jílková, Z M, Moreno-Navarrete, J M, Pavelka, S, Rodriguez-Hermosa, J I, Kopeckỳ, J, Fernández-Real, J M · 2012 · International Journal of Obesity
  18. Effects of testosterone on body composition of the aging male
    Mudali, S · 2004 · Mechanisms of Ageing and Development
  19. LKB1 and AMPK and the regulation of skeletal muscle metabolism
    Koh, Ho-Jin, Brandauer, Josef, Goodyear, Laurie J · 2008 · Current Opinion in Clinical Nutrition and Metabolic Care
  20. Long-term effects of central leptin and resistin on body weight, insulin resistance, and β-cell function and mass by the modulation of hypothalamic leptin and insulin signaling.
    Park, Sunmin, Hong, Sang Mee, Sung, So Ra, Jung, Hye Kyung · 2008 · Endocrinology
  21. RETRACTED: Redox Regulation of the AMP-Activated Protein Kinase
    Han, Yingying, Wang, Qilong, Song, Ping, Zhu, Yi, Zou, Ming-Hui · 2010 · PLoS ONE · Retracted
  22. Central leptin action improves skeletal muscle AKT, AMPK, and PGC1α activation by hypothalamic PI3K-dependent mechanism
    Roman, Erika A.F.R., Reis, Daniel, Romanatto, Talita, Maimoni, Denis, Ferreira, Eduardo A., Santos, Gustavo A., Torsoni, Adriana S., Velloso, Licio A., Torsoni, Marcio A. · 2010 · Molecular and Cellular Endocrinology
  23. Role of energy charge and AMP-activated protein kinase in adipocytes in the control of body fat stores
    Rossmeisl, M, Flachs, P, Brauner, P, Sponarova, J, Matejkova, O, Prazak, T, Ruzickova, J, Bardova, K, Kuda, O, Kopecky, J · 2004 · International Journal of Obesity
  24. CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation
    Lopez-Mejia, Isabel C., Lagarrigue, Sylviane, Giralt, Albert, Martinez-Carreres, Laia, Zanou, Nadège, Denechaud, Pierre-Damien, Castillo-Armengol, Judit, Chavey, Carine, Orpinell, Meritxell, Delacuisine, Brigitte et al. · 2017 · Molecular Cell
  25. Cloning and characterization of mouse 5′-AMP-activated protein kinase γ3 subunit
    Yu, Haiyan, Fujii, Nobuharu, Hirshman, Michael F., Pomerleau, Jason M., Goodyear, Laurie J. · 2004 · American Journal of Physiology-Cell Physiology
  26. Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet
    Tanaka, Tomohiro, Masuzaki, Hiroaki, Yasue, Shintaro, Ebihara, Ken, Shiuchi, Tetsuya, Ishii, Takako, Arai, Naoki, Hirata, Masakazu, Yamamoto, Hiroshi, Hayashi, Tatsuya et al. · 2007 · Cell Metabolism
  27. Thermogenic and metabolic antiobesity drugs: rationale and opportunities
    Clapham, J. C., Arch, J. R. S. · 2007 · Diabetes, Obesity and Metabolism
  28. Impact of estradiol, ER subtype specific agonists and genistein on energy homeostasis in a rat model of nutrition induced obesity
    Weigt, Carmen, Hertrampf, Torsten, Zoth, Nora, Fritzemeier, Karl Heinrich, Diel, Patrick · 2012 · Molecular and Cellular Endocrinology
  29. Chronic antidiabetic and cardiovascular actions of leptin: role of CNS and increased adrenergic activity
    da Silva, Alexandre A., Tallam, Lakshmi S., Liu, Jiankang, Hall, John E. · 2006 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  30. Carbohydrate ingestion does not alter skeletal muscle AMPK signaling during exercise in humans
    Lee-Young, Robert S., Palmer, Matthew J., Linden, Kelly C., LePlastrier, Kieran, Canny, Benedict J., Hargreaves, Mark, Wadley, Glenn D., Kemp, Bruce E., McConell, Glenn K. · 2006 · American Journal of Physiology-Endocrinology and Metabolism
  31. Augmenting energy expenditure by mitochondrial uncoupling: A role of AMP-activated protein kinase
    Klaus, Susanne, Keipert, Susanne, Rossmeisl, Martin, Kopecky, Jan · 2012 · Genes & Nutrition
  32. Exercise-Induced Muscle–Fat Crosstalk: Molecular Mediators and Their Pharmacological Modulation for the Maintenance of Metabolic Flexibility in Aging
    Tero-Vescan, Amelia, Degens, Hans, Matsakas, Antonios, Ștefănescu, Ruxandra, Ősz, Bianca Eugenia, Slevin, Mark · 2025 · Pharmaceuticals
  33. Adipokines in healthy skeletal muscle and metabolic disease
    Coles, C. A. · 2016 · Advances in experimental medicine and biology
  34. Skeletal muscle signaling response to sprint exercise in men and women
    Fuentes, Teresa, Guerra, Borja, Ponce-González, Jesús G., Morales-Alamo, David, Guadalupe-Grau, Amelia, Olmedillas, Hugo, Rodríguez-García, Lorena, Feijoo, David, De Pablos-Velasco, Pedro, Fernández-Pérez, Leandro et al. · 2012 · European Journal of Applied Physiology
  35. Concurrent Treatment with Ursolic Acid and Low-Intensity Treadmill Exercise Improves Muscle Atrophy and Related Outcomes in Rats
    Kim, Jae Cheol, Kang, Yun Seok, Noh, Eun Bi, Seo, Baek Woon, Seo, Dae Yun, Park, Gi Duck, Kim, Sang Hyun · 2018 · The Korean Journal of Physiology & Pharmacology
  36. Leptin Deficiency <i>Per Se</i> Dictates Body Composition and Insulin Action in <i>ob</i>/<i>ob</i> Mice
    Van Den Hoek, A. M., Teusink, B., Voshol, P. J., Havekes, L. M., Romijn, J. A., Pijl, H. · 2008 · Journal of Neuroendocrinology
  37. Role of Adipokines in Sarcopenia
    Lu, Wenhao, Feng, Wenjie, Lai, Jieyu, Yuan, Dongliang, Xiao, Wenfeng, Li, Yusheng · 2023 · Chinese Medical Journal
  38. Short-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in ob/ob mice
    Xu, Fen, Cao, Huanyi, Chen, Zonglan, Gu, Huimin, Guo, Wanrong, Lin, Beisi, Weng, Jianping · 2020 · International Journal of Obesity
  39. A New Leptin-Mediated Mechanism for Stimulating Fatty Acid Oxidation: A Pivotal Role for Sarcolemmal FAT/CD36
    Momken, Iman, Chabowski, Adrian, Dirkx, Ellen, Nabben, Miranda, Jain, Swati S., McFarlan, Jay T., Glatz, Jan F.C., Luiken, Joost J.F.P., Bonen, Arend · 2017 · Biochemical Journal
  40. Obesity and Exercise: New Insights and Perspectives
    James, Natasha Maria, Stanford, Kristin I · 2025 · Endocrine Reviews
  41. The regulatory effects of second-generation antipsychotics on lipid metabolism: potential mechanisms mediated by the gut microbiota and therapeutic implications
    Chen, Hui, Cao, Ting, Zhang, Bikui, Cai, Hualin · 2023 · Frontiers in Pharmacology
  42. Innervation of skeletal muscle by leptin receptor-containing neurons
    Babic, Tanja, Purpera, Megan N., Banfield, Bruce W., Berthoud, Hans-Rudolf, Morrison, Christopher D. · 2010 · Brain Research
  43. La fonction sécrétrice du tissu adipeux : implication dans les complications métaboliques et cardiovasculaires de l'obésité
    Guerre-Millo, Michèle · 2006 · Journal de la Société de Biologie
  44. Oral Ang-(1-7) treatment improves white adipose tissue remodeling and hypertension in rats with metabolic syndrome
    Barbosa, Maria Andréa, de Sousa, Graziele Galdino, de Castro, Uberdan Guilherme Mendes, Carneiro, Cláudia Martins, Figueiredo, Vivian Paulino, Guerra de Sá, Renata, Santos, Robson Augusto Souza dos, Alzamora, Andréia Carvalho · 2019 · Nutrition
  45. Guanethidine treatment does not block the ability of central leptin administration to decrease blood glucose concentrations in streptozotocin-induced diabetic rats
    Wang, Jinpin, Wernette, Catherine M, Judd, Robert L, Huggins, Kevin W, White, B Douglas · 2008 · Journal of Endocrinology