Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

A Proportional Hazards Model for the Subdistribution of a Competing Risk

Fine, J. P., & Gray, R. J. (1999) · Journal of the American Statistical Association · doi:10.1080/01621459.1999.10474144 · Cited by 14,290

A 17-gene stemness score for rapid determination of risk in acute leukaemia

Ng, S. W. K., Mitchell, A., Kennedy, J. A., Chen, W. C., McLeod, J., Ibrahimova, N., Arruda, A., Popescu, A., Gupta, V., Schimmer, A. D., et al. (2016) · Nature · doi:10.1038/nature20598 · Cited by 912

Deep Learning with Convolutional Neural Network for Differentiation of Liver Masses at Dynamic Contrast-enhanced CT: A Preliminary Study

Yasaka, K., Akai, H., Abe, O., & Kiryu, S. (2018) · Radiology · doi:10.1148/radiol.2017170706 · Cited by 663

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

Morita, K., Wang, F., Jahn, K., Hu, T., Tanaka, T., Sasaki, Y., Kuipers, J., Loghavi, S., Wang, S. A., Yan, Y., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19119-8 · Cited by 383

Profiling Preexisting Antibodies in Patients Treated With Anti–PD-1 Therapy for Advanced Non–Small Cell Lung Cancer

Toi, Y., Sugawara, S., Sugisaka, J., Ono, H., Kawashima, Y., Aiba, T., Kawana, S., Saito, R., Aso, M., Tsurumi, K., et al. (2019) · JAMA Oncology · doi:10.1001/jamaoncol.2018.5860 · Cited by 352

Association of Immune-Related Adverse Events with Clinical Benefit in Patients with Advanced Non-Small-Cell Lung Cancer Treated with Nivolumab

Toi, Y., Sugawara, S., Kawashima, Y., Aiba, T., Kawana, S., Saito, R., Tsurumi, K., Suzuki, K., Shimizu, H., Sugisaka, J., et al. (2018) · The Oncologist · doi:10.1634/theoncologist.2017-0384 · Cited by 294

Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV ‐8‐negative multicentric Castleman disease

Iwaki, N., Fajgenbaum, D. C., Nabel, C. S., Gion, Y., Kondo, E., Kawano, M., Masunari, T., Yoshida, I., Moro, H., Nikkuni, K., et al. (2016) · American Journal of Hematology · doi:10.1002/ajh.24242 · Cited by 296

Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors

Saito, Y., Chikenji, T. S., Matsumura, T., Nakano, M., & Fujimiya, M. (2020) · Nature Communications · doi:10.1038/s41467-020-14734-x · Cited by 196

Distinction between benign and malignant breast masses at breast ultrasound using deep learning method with convolutional neural network

Fujioka, T., Kubota, K., Mori, M., Kikuchi, Y., Katsuta, L., Kasahara, M., Oda, G., Ishiba, T., Nakagawa, T., & Tateishi, U. (2019) · Japanese Journal of Radiology · doi:10.1007/s11604-019-00831-5 · Cited by 177

Clinical utility of 30% relative decline in MRI-PDFF in predicting fibrosis regression in non-alcoholic fatty liver disease

Tamaki, N., Munaganuru, N., Jung, J., Yonan, A. Q., Loomba, R. R., Bettencourt, R., Ajmera, V., Valasek, M. A., Behling, C., Sirlin, C. B., et al. (2022) · Gut · doi:10.1136/gutjnl-2021-324264 · Cited by 130

Early change in circulating tumor DNA as a potential predictor of response to chemotherapy in patients with metastatic colorectal cancer

Osumi, H., Shinozaki, E., Yamaguchi, K., & Zembutsu, H. (2019) · Scientific Reports · doi:10.1038/s41598-019-53711-3 · Cited by 114

Cardio-Ankle Vascular Index is Independently Associated with Future Cardiovascular Events in Outpatients with Metabolic Disorders

Sato, Y., Nagayama, D., Saiki, A., Watanabe, R., Watanabe, Y., Imamura, H., Yamaguchi, T., Ban, N., Kawana, H., Nagumo, A., et al. (2016) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.31385 · Cited by 112

IL-31–generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin

Hashimoto, T., Yokozeki, H., Karasuyama, H., & Satoh, T. (2023) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2022.11.009 · Cited by 96

Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease

Tamaki, N., Ahlholm, N., Luukkonen, P. K., Porthan, K., Sharpton, S. R., Ajmera, V., Kono, Y., Dave, S., Ahmed, A., Sundaram, V., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci162513 · Cited by 69

Differential Discontinuation Profiles between Pirfenidone and Nintedanib in Patients with Idiopathic Pulmonary Fibrosis

Takehara, K., Koga, Y., Hachisu, Y., Utsugi, M., Sawada, Y., Saito, Y., Yoshimi, S., Yatomi, M., Shin, Y., Wakamatsu, I., et al. (2022) · Cells · doi:10.3390/cells11010143 · Cited by 64

Dasatinib is an effective treatment for angioimmunoblastic t-cell lymphoma

Nguyen, T. B., Sakata-Yanagimoto, M., Fujisawa, M., Nuhat, S. T., Miyoshi, H., Nannya, Y., Hashimoto, K., Fukumoto, K., Bernard, O. A., Kiyoki, Y., et al. (2020) · Cancer Research · doi:10.1158/0008-5472.can-19-2787 · Cited by 56

Stress induces insertion of calcium-permeable AMPA receptors in the OFC–BLA synapse and modulates emotional behaviours in mice

Kuniishi, H., Yamada, D., Wada, K., Yamada, M., & Sekiguchi, M. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0837-3 · Cited by 47

The prognostic significance of pneumothorax in patients with idiopathic pulmonary fibrosis

Nishimoto, K., Fujisawa, T., Yoshimura, K., Enomoto, Y., Enomoto, N., Nakamura, Y., Inui, N., Sumikawa, H., Johkoh, T., Colby, T. V., et al. (2018) · Respirology · doi:10.1111/resp.13219 · Cited by 47

Biallelic VPS35L pathogenic variants cause 3C/Ritscher-Schinzel-like syndrome through dysfunction of retriever complex

Kato, K., Oka, Y., Muramatsu, H., Vasilev, F. F., Otomo, T., Oishi, H., Kawano, Y., Kidokoro, H., Nakazawa, Y., Ogi, T., et al. (2020) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2019-106213 · Cited by 42

INPP5D mRNA Expression and Cognitive Decline in Japanese Alzheimer’s Disease Subjects

Yoshino, Y., Yamazaki, K., Ozaki, Y., Sao, T., Yoshida, T., Mori, T., Mori, Y., Ochi, S., Iga, J.-I., & Ueno, S.-I. (2017) · Journal of Alzheimer's Disease · doi:10.3233/jad-161211 · Cited by 41

The association between the incidence of intestinal graft‐vs‐host disease and antibiotic use after allogeneic hematopoietic stem cell transplantation

Hidaka, D., Hayase, E., Shiratori, S., Hasegawa, Y., Ishio, T., Tateno, T., Okada, K., Goto, H., Sugita, J., Onozawa, M., et al. (2018) · Clinical Transplantation · doi:10.1111/ctr.13361 · Cited by 39

Micafungin breakthrough fungemia in patients with hematological disorders

Kimura, M., Araoka, H., Yamamoto, H., Nakamura, S., Nagi, M., Yamagoe, S., Miyazaki, Y., Ogura, S., Mitsuki, T., Yuasa, M., et al. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02183-17 · Cited by 37

The EUTOS long‐term survival score predicts disease‐specific mortality and molecular responses among patients with chronic myeloid leukemia in a practice‐based cohort

Sato, E., Iriyama, N., Tokuhira, M., Takaku, T., Ishikawa, M., Nakazato, T., Sugimoto, K., Fujita, H., Kimura, Y., Fujioka, I., et al. (2020) · Cancer Medicine · doi:10.1002/cam4.3516 · Cited by 35

Preventive effects of tea and tea catechins against influenza and acute upper respiratory tract infections: a systematic review and meta-analysis

Umeda, M., Tominaga, T., Kozuma, K., Kitazawa, H., Furushima, D., Hibi, M., & Yamada, H. (2021) · European Journal of Nutrition · doi:10.1007/s00394-021-02681-2 · Cited by 31

Effect of phospholipid curcumin Meriva on liver histology and kidney disease in nonalcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial

Musso, G., Pinach, S., Mariano, F., Saba, F., De Michieli, F., Framarin, L., Berrutti, M., Paschetta, E., Parente, R., Lizet Castillo, Y., et al. (2025) · Hepatology · doi:10.1097/hep.0000000000000937 · Cited by 31

Six-transmembrane epithelial antigen of the prostate 1 protects against increased oxidative stress via a nuclear erythroid 2-related factor pathway in colorectal cancer

Nakamura, H., Takada, K., Arihara, Y., Hayasaka, N., Murase, K., Iyama, S., Kobune, M., Miyanishi, K., & Kato, J. (2019) · Cancer Gene Therapy · doi:10.1038/s41417-018-0056-8 · Cited by 29

Reticulocyte count is the most important predictor of acute cerebral ischemia and high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia

Belisário, A. R., Sales, R. R., Toledo, N. E., Muniz, M. B. D. S. R., Velloso-Rodrigues, C., Silva, C. M., & Viana, M. B. (2016) · Annals of Hematology · doi:10.1007/s00277-016-2789-5 · Cited by 29

The relationship between the deep squat movement and the hip, knee and ankle range of motion and muscle strength

Endo, Y., Miura, M., & Sakamoto, M. (2020) · Journal of Physical Therapy Science · doi:10.1589/jpts.32.391 · Cited by 29

Fluorescence real-time kinetics of protoporphyrin IX after 5-ALA administration in low-grade glioma

Kaneko, S., Suero Molina, E., Sporns, P., Schipmann, S., Black, D., & Stummer, W. (2022) · Journal of Neurosurgery · doi:10.3171/2020.10.jns202881 · Cited by 28

Factors affecting the grieving process after perinatal loss

Kishimoto, M., Yamaguchi, A., Niimura, M., Mizumoto, M., Hikitsuchi, T., Ogawa, K., Ozawa, N., & Tachibana, Y. (2021) · BMC Women's Health · doi:10.1186/s12905-021-01457-4 · Cited by 27

Clinical efficacy of haematopoietic stem cell transplantation for adult adrenoleukodystrophy

Matsukawa, T., Yamamoto, T., Honda, A., Toya, T., Ishiura, H., Mitsui, J., Tanaka, M., Hao, A., Shinohara, A., Ogura, M., et al. (2020) · Brain Communications · doi:10.1093/braincomms/fcz048 · Cited by 26

Correlation between thyroid transcription factor-1 expression, immune-related thyroid dysfunction, and efficacy of anti-programmed cell death protein-1 treatment in non-small cell lung cancer

Koyama, J., Horiike, A., Yoshizawa, T., Dotsu, Y., Ariyasu, R., Saiki, M., Sonoda, T., Uchibori, K., Nishikawa, S., Kitazono, S., et al. (2019) · Journal of Thoracic Disease · doi:10.21037/jtd.2019.04.102 · Cited by 23

Cetuximab Enhances the Efficacy of MRTX1133, a Novel KRASG12DInhibitor, in Colorectal Cancer Treatment

KATAOKA, M., KITAZAWA, M., NAKAMURA, S., KOYAMA, M., YAMAMOTO, Y., MIYAZAKI, S., HONDO, N., TANAKA, H., & SOEJIMA, Y. (2023) · Anticancer Research · doi:10.21873/anticanres.16629 · Cited by 25

Clinical features associated with NeoRAS wild-type metastatic colorectal cancer A SCRUM-Japan GOZILA substudy

Osumi, H., Shinozaki, E., Nakamura, Y., Esaki, T., Yasui, H., Taniguchi, H., Satake, H., Sunakawa, Y., Komatsu, Y., Kagawa, Y., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50026-4 · Cited by 17

A retrospective multicenter study of bone mineral density in adolescents and adults with Turner syndrome in Japan

Itonaga, T., Koga, E., Nishigaki, S., Kawai, M., Sakakibara, H., & Hasegawa, Y. (2020) · Endocrine Journal · doi:10.1507/endocrj.ej20-0083 · Cited by 16

A multi-institutional observational study evaluating the incidence and the clinicopathological characteristics of NeoRAS wild-type metastatic colorectal cancer

Osumi, H., Takashima, A., Ooki, A., Yoshinari, Y., Wakatsuki, T., Hirano, H., Nakayama, I., Okita, N., Sawada, R., Ouchi, K., et al. (2023) · Translational Oncology · doi:10.1016/j.tranon.2023.101718 · Cited by 16

Circulating S100A8/A9 is potentially a biomarker that could reflect the severity of experimental colitis in rats

Okada, K., Itoh, H., & Ikemoto, M. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e03470 · Cited by 15

Determining whether the effect of liraglutide on non-alcoholic fatty liver disease depends on reductions in the body mass index

Shiomi, M., Tanaka, Y., Takada, T., & Otori, K. (2020) · JGH Open · doi:10.1002/jgh3.12384 · Cited by 13

Diagnostic analysis of lupus anticoagulant using clot waveform analysis in activated partial thromboplastin time prolonged cases: A retrospective analysis

Kanouchi, K., Narimatsu, H., Shirata, T., & Morikane, K. (2021) · Health Science Reports · doi:10.1002/hsr2.258 · Cited by 13

WEE1 Inhibitor Adavosertib Exerts Antitumor Effects on Colorectal Cancer, Especially in Cases with p53 Mutations

Ariyoshi, M., Yuge, R., Kitadai, Y., Shimizu, D., Miyamoto, R., Yamashita, K., Hiyama, Y., Takigawa, H., Urabe, Y., & Oka, S. (2024) · Cancers · doi:10.3390/cancers16183136 · Cited by 12

Dynamic Changes in Circulating Tumor DNA During Immunotherapy for Head and Neck Cancer: SHIZUKU-HN Study

Noji, R., Tohyama, K., Nakamura, S., Naito, T., Oikawa, Y., Kuroshima, T., Tomioka, H., Michi, Y., Ikeda, S., Asakage, T., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms26010235 · Cited by 11

Psychological distress in post‐partum women after non‐invasive prenatal testing (NIPT) in Japan

Takeda, E., Suzumori, N., Ebara, T., Yotsumoto, J., Kumagai, K., Oseto, K., Numabe, H., & Sugiura‐Ogasawara, M. (2018) · Journal of Obstetrics and Gynaecology Research · doi:10.1111/jog.13483 · Cited by 10

Comparison of the efficacy and safety of insulin degludec/aspart (twice-daily injections), insulin glargine 300 u/ml, and insulin glulisine (basal-bolus therapy)

Kawaguchi, Y., Sawa, J., Hamai, C., Nishimura, Y., & Kumeda, Y. (2019) · Journal of Diabetes Investigation · doi:10.1111/jdi.13038 · Cited by 10

Expression of Oncogenic Molecules in Pediatric Ulcerative Colitis

Arai, N., Kudo, T., Tokita, K., Kyodo, R., Sato, M., Miyata, E., Hosoi, K., Ikuse, T., Jimbo, K., Ohtsuka, Y., et al. (2022) · Digestion · doi:10.1159/000519559 · Cited by 9

Increased Interleukin-17-Producing γδT Cells in the Brain Exacerbate the Pathogenesis of Sepsis-Associated Encephalopathy and Sepsis-Induced Anxiety in Mice

Moriyama, N., Saito, M., Ono, Y., Yamashita, K., Aoi, T., & Kotani, J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12134309 · Cited by 7

Nutrition-related Risk and Severe Hypoglycemia in Older Adult Outpatients with and without Diabetes

Kimura, Y., Kimura, N., & Akazawa, M. (2022) · Clinical Case Reports · doi:10.1002/ccr3.5317 · Cited by 6

Firing Activities of REM- and NREM-Preferring Neurons Are Differently Modulated by Fast Network Oscillations and Behavior in the Hippocampus, Prelimbic Cortex, and Amygdala

Kajiya, R., Miyawaki, H., Nakahara, H., & Mizuseki, K. (2025) · eneuro · doi:10.1523/eneuro.0575-24.2025 · Cited by 4

Efficacy of anti-epidermal growth factor antibody rechallenge in RAS/BRAF wild-type metastatic colorectal cancer: a multi-institutional observational study

Fukuda, K., Osumi, H., Yoshinami, Y., Ooki, A., Takashima, A., Wakatsuki, T., Hirano, H., Nakayama, I., Ouchi, K., Sawada, R., et al. (2024) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-024-05893-1 · Cited by 5

Rare TCF3 variants associated with pediatric B cell acute lymphoblastic leukemia

Miyamoto, S., Urayama, K. Y., Arakawa, Y., Koh, K., Yuza, Y., Hasegawa, D., Taneyama, Y., Noguchi, Y., Yanagimachi, M., Inukai, T., et al. (2024) · Pediatric Hematology and Oncology · doi:10.1080/08880018.2023.2201302 · Cited by 4

Clinical applicability of the ELN2020 criteria for tyrosine kinase inhibitor discontinuation in chronic myeloid leukemia: insights from a multicenter retrospective study in real-world practice

Hibino, Y., Fujisawa, S., Fujimaki, K., Hagihara, M., Fujita, H., Tanaka, M., Takayama, K., Takeda, T., Matsumura, A., Suzuki, T., et al. (2025) · Leukemia Research · doi:10.1016/j.leukres.2025.107689 · Cited by 2

Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome

Tatetsu, H., Watanabe, M., Liu, J., Tokunaga, K., Iwanaga, E., Komohara, Y., Thrash, E., Bassal, M. A., Matsuoka, M., Tenen, D. G., et al. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1327 · Cited by 1