Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016) · Nature · doi:10.1038/nature17946 · Cited by 5,437

CCTop: An intuitive, flexible and reliable CRISPR/Cas9 target prediction tool

Stemmer, M., Thumberger, T., del Sol Keyer, M., Wittbrodt, J., & Mateo, J. L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124633 · Cited by 1,088

CRISPR-P: A Web Tool for Synthetic Single-Guide RNA Design of CRISPR-System in Plants

Yang, L., Lü, L., Liu, H., Li, S., Feng, X., & Chen, L. (2014) · Molecular Plant · doi:10.1093/mp/ssu044 · Cited by 815

Both CRISPR / C as‐based nucleases and nickases can be used efficiently for genome engineering in A rabidopsis thaliana

Fauser, F., Schiml, S., & Puchta, H. (2014) · The Plant Journal · doi:10.1111/tpj.12554 · Cited by 733

Resistance to AHAS inhibitor herbicides: current understanding

Yu, Q. P., & Powles, S. B. (2013) · Pest Management Science · doi:10.1002/ps.3710 · Cited by 503

Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence

Ryan, M. D., King, A. M. Q., & Thomas, G. P. (1991) · Journal of General Virology · doi:10.1099/0022-1317-72-11-2727 · Cited by 487

A Highly Efficient Transformation Protocol for Micro-Tom, a Model Cultivar for Tomato Functional Genomics

Sun, H., Uchii, S., Watanabe, S., & Ezura, H. (2005) · Plant and Cell Physiology · doi:10.1093/pcp/pci251 · Cited by 476

Precise Editing of a Target Base in the Rice Genome Using a Modified CRISPR/Cas9 System

Lu, Y., & Zhu, J. (2016) · Molecular Plant · doi:10.1016/j.molp.2016.11.013 · Cited by 423

Rapid and efficientAgrobacterium-mediated transformation in rice

Toki, S. (1997) · Plant Molecular Biology Reporter · doi:10.1007/bf02772109 · Cited by 381

Efficient gene targeting by homologous recombination in rice

Terada, R., Urawa, H., Inagaki, Y., Tsugane, K., & Iida, S. (2002) · Nature Biotechnology · doi:10.1038/nbt737 · Cited by 327

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Anzalone, A. V., Koblan, L. W., & Liu, D. R. (2020) · Nature Biotechnology · doi:10.1038/s41587-020-0561-9 · Cited by 2,237

Impact of Climate Change on Crops Adaptation and Strategies to Tackle Its Outcome: A Review

Raza, A., Razzaq, A., Mehmood, S. S., Zou, X., Zhang, X., Lv, Y., & Xu, J. (2019) · Plants · doi:10.3390/plants8020034 · Cited by 1,762

Base editing: precision chemistry on the genome and transcriptome of living cells

Rees, H. A., & Liu, D. R. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0059-1 · Cited by 1,675

CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture

Chen, K., Wang, Y., Zhang, R., Zhang, H., & Gao, C. (2019) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050718-100049 · Cited by 1,696

Genome engineering for crop improvement and future agriculture

Gao, C. (2021) · Cell · doi:10.1016/j.cell.2021.01.005 · Cited by 1,070

Applications of CRISPR–Cas in agriculture and plant biotechnology

Zhu, H., Li, C., & Gao, C. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00288-9 · Cited by 870

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity

Komor, A. C., Zhao, K. T., Packer, M. S., Gaudelli, N. M., Waterbury, A. L., Koblan, L. W., Kim, Y. B., Badran, A. H., & Liu, D. R. (2017) · Science Advances · doi:10.1126/sciadv.aao4774 · Cited by 783

CRISPR for Crop Improvement: An Update Review

Jaganathan, D., Ramasamy, K., Sellamuthu, G., Jayabalan, S., & Venkataraman, G. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.00985 · Cited by 619

A Multipurpose Toolkit to Enable Advanced Genome Engineering in Plants

Čermák, T., Curtin, S. J., Gil‐Humanes, J., Čegan, R., Kono, T. J. Y., Konečná, E., Belanto, J. J., Starker, C. G., Mathre, J. W., Greenstein, R. L., et al. (2017) · The Plant Cell · doi:10.1105/tpc.16.00922 · Cited by 668

EditR: A Method to Quantify Base Editing from Sanger Sequencing

Kluesner, M. G., Nedveck, D. A., Lahr, W. S., Garbe, J. R., Abrahante, J. E., Webber, B. R., & Moriarity, B. S. (2018) · The CRISPR Journal · doi:10.1089/crispr.2018.0014 · Cited by 565

Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion

Li, C., Zong, Y., Wang, Y., Jin, S., Zhang, D., Song, Q., Zhang, R., & Gao, C. (2018) · Genome biology · doi:10.1186/s13059-018-1443-z · Cited by 507

Progress and prospects in plant genome editing

Yin, K., Gao, C., & Qiu, J. (2017) · Nature Plants · doi:10.1038/nplants.2017.107 · Cited by 445

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities

Gehrke, J. M., Cervantes, O., Clement, K., Wu, Y., Zeng, J., Bauer, D. E., Pinello, L., & Joung, J. K. (2018) · Nature Biotechnology · doi:10.1038/nbt.4199 · Cited by 439

The emerging and uncultivated potential of CRISPR technology in plant science

Zhang, Y., Malzahn, A. A., Sretenovic, S., & Qi, Y. (2019) · Nature Plants · doi:10.1038/s41477-019-0461-5 · Cited by 414

Precise plant genome editing using base editors and prime editors

Molla, K. A., Sretenovic, S., Bansal, K. C., & Qi, Y. (2021) · Nature Plants · doi:10.1038/s41477-021-00991-1 · Cited by 387

Transgene-Free Genome Editing in Tomato and Potato Plants Using Agrobacterium-Mediated Delivery of a CRISPR/Cas9 Cytidine Base Editor

Veillet, F., Perrot, L., Chauvin, L., Kermarrec, M.-P., Guyon‐Debast, A., Chauvin, J.-É., Nogué, F., & Mazier, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20020402 · Cited by 370

CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

Billon, P., Bryant, E. E., Joseph, S. A., Nambiar, T. S., Hayward, S. B., Rothstein, R., & Ciccia, A. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.08.008 · Cited by 363

Gene editing in plants: progress and challenges

Mao, Y., Botella, J. R., Liu, Y., & Zhu, J. (2019) · National Science Review · doi:10.1093/nsr/nwz005 · Cited by 353

Generation of herbicide tolerance traits and a new selectable marker in wheat using base editing

Zhang, R., Liu, J., Chai, Z., Chen, S., Bai, Y., Zong, Y., Chen, K., Li, J., Jiang, L., & Gao, C. (2019) · Nature Plants · doi:10.1038/s41477-019-0405-0 · Cited by 340

ICE-CBF-COR Signaling Cascade and Its Regulation in Plants Responding to Cold Stress

Hwarari, D., Guan, Y., Ahmad, B., Movahedi, A., Min, T., Hao, Z., Lu, Y., Chen, J., & Yang, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031549 · Cited by 339

CRISPR/Cas-Mediated Base Editing: Technical Considerations and Practical Applications

Molla, K. A., & Yang, Y. (2019) · Trends in biotechnology · doi:10.1016/j.tibtech.2019.03.008 · Cited by 348

Application of protoplast technology to CRISPR/Cas9 mutagenesis: from single‐cell mutation detection to mutant plant regeneration

Lin, C., Hsu, C., Yang, L., Lee, L., Fu, J., Cheng, Q., Wu, F., Hsiao, H. C. W., Zhang, Y., Zhang, R., et al. (2017) · Plant Biotechnology Journal · doi:10.1111/pbi.12870 · Cited by 341

Engineering herbicide-resistant watermelon variety through CRISPR/Cas9-mediated base-editing

Tian, S., Jiang, L., Cui, X., Zhang, J., Guo, S., Li, M., Zhang, H., Ren, Y., Gong, G., Zong, M., et al. (2018) · Plant Cell Reports · doi:10.1007/s00299-018-2299-0 · Cited by 307

Precision genome engineering through adenine base editing in plants

Kang, B., Yun, J., Kim, S., Shin, Y., Ryu, J., Choi, M., Woo, J. W., & Kim, J. (2018) · Nature Plants · doi:10.1038/s41477-018-0178-x · Cited by 306

Novel CRISPR–Cas Systems: An Updated Review of the Current Achievements, Applications, and Future Research Perspectives

Nidhi, S., Anand, U., Olekšák, P., Tripathi, P., Lal, J. A., Thomas, G., Kuča, K., & Tripathi, V. S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073327 · Cited by 310

CRISPR Crops: Plant Genome Editing Toward Disease Resistance

Langner, T., Kamoun, S., & Belhaj, K. (2018) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-080417-050158 · Cited by 301

The delivery challenge: fulfilling the promise of therapeutic genome editing

van Haasteren, J., Li, J., Scheideler, O. J., Murthy, N., & Schaffer, D. V. (2020) · Nature Biotechnology · doi:10.1038/s41587-020-0565-5 · Cited by 285

Plant genome editing with TALEN and CRISPR

Malzahn, A. A., Lowder, L. G., & Qi, Y. (2017) · Cell & Bioscience · doi:10.1186/s13578-017-0148-4 · Cited by 288

Genome Edited Crops Touch the Market: A View on the Global Development and Regulatory Environment

Menz, J., Modrzejewski, D., Hartung, F., Wilhelm, R., & Sprink, T. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.586027 · Cited by 275

MicroTom Metabolic Network: Rewiring Tomato Metabolic Regulatory Network throughout the Growth Cycle

Li, Y., Chen, Y., Zhou, L., You, S., Deng, H., Chen, Y., Alseekh, S., Yuan, Y., Fu, R., Zhang, Z., et al. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.06.005 · Cited by 270

Targeted genome-modification tools and their advanced applications in crop breeding

Li, B., Sun, C., Li, J., & Gao, C. (2024) · Nature Reviews Genetics · doi:10.1038/s41576-024-00720-2 · Cited by 269

Use of CRISPR systems in plant genome editing: toward new opportunities in agriculture

Ricroch, A., Clairand, P., & Harwood, W. (2017) · Emerging Topics in Life Sciences · doi:10.1042/etls20170085 · Cited by 252

Rewritable multi-event analog recording in bacterial and mammalian cells

Tang, W., & Liu, D. R. (2018) · Science · doi:10.1126/science.aap8992 · Cited by 255

Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective

Zhang, D., Hussain, A., Manghwar, H., Xie, K., Xie, S., Zhao, S., Larkin, R. M., Qing, P., Jin, S., & Ding, F. (2020) · Plant Biotechnology Journal · doi:10.1111/pbi.13383 · Cited by 254

Application of CRISPR/Cas9-mediated gene editing for abiotic stress management in crop plants

Kumar, M., Prusty, M. R., Pandey, M. K., Singh, P. K., Bohra, A., Guo, B. Z., & Varshney, R. K. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2023.1157678 · Cited by 251

Inorganic arsenic toxicity and alleviation strategies in rice

Mawia, A. M., Hui, S., Zhou, L., Li, H., Tabassum, J., Lai, C., Wang, J., Shao, G., Wei, X., Tang, S., et al. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.124751 · Cited by 237

PAM-less plant genome editing using a CRISPR–SpRY toolbox

Ren, Q., Sretenovic, S., Liu, S., Tang, X. D., Huang, L., He, Y., Liu, L., Guo, Y., Zhong, Z., Liu, G., et al. (2021) · Nature Plants · doi:10.1038/s41477-020-00827-4 · Cited by 244

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes

Hess, G. T., Tycko, J., Yao, D., & Bassik, M. C. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.09.029 · Cited by 234

Base editing in crops: current advances, limitations and future implications

Mishra, R., Joshi, R. K., & Zhao, K. (2019) · Plant Biotechnology Journal · doi:10.1111/pbi.13225 · Cited by 238

Improved Base Editor for Efficiently Inducing Genetic Variations in Rice with CRISPR/Cas9-Guided Hyperactive hAID Mutant

Ren, B., Yan, F., Kuang, Y., Li, N., Zhang, D., Zhou, X., Lin, H., & Zhou, H. (2018) · Molecular Plant · doi:10.1016/j.molp.2018.01.005 · Cited by 230

CRISPR base editors: genome editing without double-stranded breaks

Eid, A., Alshareef, S. A., & Mahfouz, M. M. (2018) · Biochemical Journal · doi:10.1042/bcj20170793 · Cited by 237

CRISPR technology is revolutionizing the improvement of tomato and other fruit crops

Wang, T., Zhang, H., & Zhu, H. (2019) · Horticulture Research · doi:10.1038/s41438-019-0159-x · Cited by 236

Principles, Applications, and Biosafety of Plant Genome Editing Using CRISPR-Cas9

El‐Mounadi, K., Morales-Floriano, M. L., & García-Ruíz, H. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.00056 · Cited by 231

Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants

Zaidi, S. S.-E.-A., Mahas, A., Vanderschuren, H., & Mahfouz, M. M. (2020) · Genome Biology · doi:10.1186/s13059-020-02204-y · Cited by 221

Deaminase-mediated multiplex genome editing in Escherichia coli

Banno, S., Nishida, K., Arazoe, T., Mitsunobu, H., & Kondo, A. (2018) · Nature Microbiology · doi:10.1038/s41564-017-0102-6 · Cited by 213

In Vivo AAV-CRISPR/Cas9–Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia

Zhao, H., Li, Y., He, L., Pu, W., Yu, W., Li, Y., Wu, Y., Xu, C., Wei, Y., Ding, Q., et al. (2019) · Circulation · doi:10.1161/circulationaha.119.042476 · Cited by 214

Modern Trends in Plant Genome Editing: An Inclusive Review of the CRISPR/Cas9 Toolbox

Razzaq, A., Saleem, F., Kanwal, M., Mustafa, G., Yousaf, S., Arshad, H. M. I., Hameed, M. K., Khan, M. S., & Joyia, F. A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20164045 · Cited by 216

Development of Plant Prime-Editing Systems for Precise Genome Editing

Xu, R., Li, J., Liu, X., Shan, T., Qin, R., & Wei, P. (2020) · Plant Communications · doi:10.1016/j.xplc.2020.100043 · Cited by 209

Genome Editing in Rice: Recent Advances, Challenges, and Future Implications

Mishra, R., Joshi, R. K., & Zhao, K. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.01361 · Cited by 206

CRISPR / dC as9 platforms in plants: strategies and applications beyond genome editing

Moradpour, M., & Abdulah, S. N. A. (2019) · Plant Biotechnology Journal · doi:10.1111/pbi.13232 · Cited by 205

Yarrowia lipolytica Strains and Their Biotechnological Applications: How Natural Biodiversity and Metabolic Engineering Could Contribute to Cell Factories Improvement

Madzak, C. (2021) · Journal of Fungi · doi:10.3390/jof7070548 · Cited by 213

Improving Plant Genome Editing with High-Fidelity xCas9 and Non-canonical PAM-Targeting Cas9-NG

Zhong, Z., Sretenovic, S., Ren, Q., Yang, L., Bao, Y., Qi, C., Yuan, M., He, Y., Liu, S., Liu, X., et al. (2019) · Molecular Plant · doi:10.1016/j.molp.2019.03.011 · Cited by 201

Genome Editing in Plants: Exploration of Technological Advancements and Challenges

Vats, S., Kumawat, S., Kumar, V., Patil, G., Joshi, T., Sonah, H., Sharma, T. R., & Deshmukh, R. K. (2019) · Cells · doi:10.3390/cells8111386 · Cited by 195

Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system

Zhang, Y., Qin, W., Lu, X., Xu, J., Huang, H., Bai, H., Li, S., & Lin, S. (2017) · Nature Communications · doi:10.1038/s41467-017-00175-6 · Cited by 188

Trait discovery and editing in tomato

Rothan, C., Diouf, I., & Causse, M. (2018) · The Plant Journal · doi:10.1111/tpj.14152 · Cited by 188

Genome editing in plants by engineered CRISPR–Cas9 recognizing NG PAM

Endo, M., Mikami, M., Endo, A., Kaya, H., Itoh, T., Nishimasu, H., Nureki, O., & Toki, S. (2018) · Nature Plants · doi:10.1038/s41477-018-0321-8 · Cited by 186

Development of CRISPR-Cas systems for genome editing and beyond

Zhang, F. (2019) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583519000052 · Cited by 188

Mutation of GmAITR Genes by CRISPR/Cas9 Genome Editing Results in Enhanced Salinity Stress Tolerance in Soybean

Wang, T., Xun, H., Wang, W., Ding, X., Tian, H., Hussain, S., Dong, Q., Li, Y., Cheng, Y., Wang, C., et al. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.779598 · Cited by 188

Mimicking natural polymorphism in eIF 4E by CRISPR ‐Cas9 base editing is associated with resistance to potyviruses

Bastet, A., Zafirov, D., Giovinazzo, N., Guyon‐Debast, A., Nogué, F., Robaglia, C., & Gallois, J. (2019) · Plant Biotechnology Journal · doi:10.1111/pbi.13096 · Cited by 189

Chloroplast and mitochondrial DNA editing in plants

Kang, B., Bae, S., Lee, S., Lee, J. S., Kim, A., Lee, H., Baek, G., Seo, H., Kim, J., & Kim, J. (2021) · Nature Plants · doi:10.1038/s41477-021-00943-9 · Cited by 186

High‐efficient and precise base editing of C•G to T•A in the allotetraploid cotton (Gossypium hirsutum) genome using a modified CRISPR /Cas9 system

Qin, L., Li, J., Wang, Q., Xu, Z., Sun, L., Alariqi, M., Manghwar, H., Wang, G., Li, B., Ding, X. L., et al. (2019) · Plant Biotechnology Journal · doi:10.1111/pbi.13168 · Cited by 179

MACBETH: Multiplex automated Corynebacterium glutamicum base editing method

Wang, Y., Liu, Y., Liu, J., Guo, Y., Fan, L., Ni, X., Zheng, X., Wang, M., Zheng, P., Sun, J., et al. (2018) · Metabolic Engineering · doi:10.1016/j.ymben.2018.02.016 · Cited by 178

Precision genome editing using cytosine and adenine base editors in mammalian cells

Huang, T. P., Newby, G. A., & Liu, D. R. (2021) · Nature Protocols · doi:10.1038/s41596-020-00450-9 · Cited by 175

Genome Editing—Principles and Applications for Functional Genomics Research and Crop Improvement

Zhang, H., Zhang, J., Lang, Z., Botella, J. R., & Zhu, J. (2017) · Critical Reviews in Plant Sciences · doi:10.1080/07352689.2017.1402989 · Cited by 179

CRISPR-Cas9/Cas12a biotechnology and application in bacteria

Yao, R., Liu, D., Jia, X., Zheng, Y., Liu, W. Y., & Xiao, Y. (2018) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2018.09.004 · Cited by 165

Single transcript unit CRISPR 2.0 systems for robust Cas9 and Cas12a mediated plant genome editing

Tang, X. D., Ren, Q., Yang, L., Bao, Y., Zhong, Z., He, Y., Liu, S., Qi, C., Liu, B., Wang, Y., et al. (2018) · Plant Biotechnology Journal · doi:10.1111/pbi.13068 · Cited by 156

Cas9-NG Greatly Expands the Targeting Scope of the Genome-Editing Toolkit by Recognizing NG and Other Atypical PAMs in Rice

Ren, B., Liu, L., Li, S., Kuang, Y., Wang, J., Zhang, D., Zhou, X., Lin, H., & Zhou, H. (2019) · Molecular Plant · doi:10.1016/j.molp.2019.03.010 · Cited by 148

A Critical Review: Recent Advancements in the Use of CRISPR/Cas9 Technology to Enhance Crops and Alleviate Global Food Crises

Rasheed, A., Gill, R. A., Hassan, M., Mahmood, A., Qari, S. H., Zaman, Q. U., Ilyas, M., Aamer, M., Batool, M., Li, H., et al. (2021) · Current Issues in Molecular Biology · doi:10.3390/cimb43030135 · Cited by 154

Characterisation of CRISPR mutants targeting genes modulating pectin degradation in ripening tomato

Wang, D., Samsulrizal, N. H., Yan, C., Allcock, N., Craigon, J., Blanco‐Ulate, B., Ortega‐Salazar, I., Marcus, S. E., Bagheri, H., Pérez-Fons, L., et al. (2018) · PLANT PHYSIOLOGY · doi:10.1104/pp.18.01187 · Cited by 144

Can gene editing reduce postharvest waste and loss of fruit, vegetables, and ornamentals?

Shipman, E. N., Yu, J., Zhou, J., Albornoz, K., & Beckles, D. M. (2020) · Horticulture Research · doi:10.1038/s41438-020-00428-4 · Cited by 141

High-efficiency and multiplex adenine base editing in plants using new TadA variants

Yan, D., Ren, B., Liu, L., Yan, F., Li, S., Wang, G., Sun, W., Zhou, X., & Zhou, H. (2021) · Molecular Plant · doi:10.1016/j.molp.2021.02.007 · Cited by 140

MADS-box genes and crop domestication: the jack of all traits

Schilling, S., Pan, S., Kennedy, A., & Melzer, R. (2018) · Journal of Experimental Botany · doi:10.1093/jxb/erx479 · Cited by 139

Precise gene replacement in rice by RNA transcript-templated homologous recombination

Li, S., Li, J., He, Y., Xu, M., Zhang, J., Du, W., Zhao, Y., & Xia, L. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0065-7 · Cited by 137

Enhanced base editing by co-expression of free uracil DNA glycosylase inhibitor

Wang, L., Xue, W., Yan, L., Li, X., Wei, J., Chen, M., Wu, J., Yang, B., Yang, L. C., & Chen, J. (2017) · Cell Research · doi:10.1038/cr.2017.111 · Cited by 139

Construct design for CRISPR/Cas-based genome editing in plants

Hassan, M. M., Zhang, Y., Yuan, G., De, K., Chen, J., Muchero, W., Tuskan, G. A., Qi, Y., & Yang, X. (2021) · Trends in Plant Science · doi:10.1016/j.tplants.2021.06.015 · Cited by 139

Genome Editing in Cereals: Approaches, Applications and Challenges

Ansari, W. A., Chandanshive, S. U., Bhatt, V. D., Nadaf, A. B., Vats, S., Katara, J. L., Sonah, H., & Deshmukh, R. K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21114040 · Cited by 138

CRISPR/Cas Genome Editing Technologies for Plant Improvement against Biotic and Abiotic Stresses: Advances, Limitations, and Future Perspectives

Wang, Y., Zafar, N., Ali, Q., Manghwar, H., Wang, G., Yu, L., Ding, X. L., Ding, F., Hong, N., Wang, G., et al. (2022) · Cells · doi:10.3390/cells11233928 · Cited by 141

Mutation Breeding in Tomato: Advances, Applicability and Challenges

Chaudhary, J., Alisha, A., Bhatt, V. D., Chandanshive, S., Kumar, N., Mir, Z. A., Kumar, A., Yadav, S. K., Shivaraj, S. M., Sonah, H., et al. (2019) · Plants · doi:10.3390/plants8050128 · Cited by 134

The CRISPR/Cas revolution continues: From efficient gene editing for crop breeding to plant synthetic biology

Kumlehn, J., Pietralla, J., Hensel, G., Pacher, M., & Puchta, H. (2018) · Journal of Integrative Plant Biology · doi:10.1111/jipb.12734 · Cited by 142

Evolution of Alternative Adaptive Immune Systems in Vertebrates

Boehm, T. L. J., Hirano, M., Holland, S. J., Das, S., Schorpp, M., & Cooper, M. D. (2017) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042617-053028 · Cited by 133

Improved plant cytosine base editors with high editing activity, purity, and specificity

Ren, Q., Sretenovic, S., Liu, G., Zhong, Z., Wang, J., Huang, L., Tang, X., Guo, Y., Liu, L., Wu, Y., et al. (2021) · Plant Biotechnology Journal · doi:10.1111/pbi.13635 · Cited by 131

Biotechnological Advances to Improve Abiotic Stress Tolerance in Crops

Villalobos-López, M. Á., Arroyo-Becerra, A., Quintero-Jiménez, A., & Iturriaga, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231912053 · Cited by 129

CRISPR/dCas9-Based Systems: Mechanisms and Applications in Plant Sciences

Karlson, C. K. S., Noor, S. N. M., Nolte, N., & Tan, B. C. (2021) · Plants · doi:10.3390/plants10102055 · Cited by 139

Multiplex genome-editing technologies for revolutionizing plant biology and crop improvement

Abdelrahman, M., Wei, Z., Rohila, J. S., & Zhao, K. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.721203 · Cited by 125

The Solanum tuberosum GBSSI gene: a target for assessing gene and base editing in tetraploid potato

Veillet, F., Chauvin, L., Kermarrec, M.-P., Sevestre, F., Merrer, M., Terret, Z., Szydlowski, N., Devaux, P., Gallois, J.-L., & Chauvin, J.-E. (2019) · Plant Cell Reports · doi:10.1007/s00299-019-02426-w · Cited by 124

What is the available evidence for the range of applications of genome-editing as a new tool for plant trait modification and the potential occurrence of associated off-target effects: a systematic map

Modrzejewski, D., Hartung, F., Sprink, T., Krause, D., Kohl, C., & Wilhelm, R. (2019) · Environmental Evidence · doi:10.1186/s13750-019-0171-5 · Cited by 134

Mechanistic insights of CRISPR /Cas‐mediated genome editing towards enhancing abiotic stress tolerance in plants

Bhat, M. A., Mir, R. A., Kumar, V., Shah, A. A., Zargar, S. M., Rahman, S., & Jan, A. T. (2021) · Physiologia Plantarum · doi:10.1111/ppl.13359 · Cited by 120

Base editing in plants: Current status and challenges

Bharat, S. S., Li, S., Li, J., Yan, L., & Xia, L. (2019) · The Crop Journal · doi:10.1016/j.cj.2019.10.002 · Cited by 126

Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation

Mahas, A., Neal Stewart, C., & Mahfouz, M. M. (2018) · Biotechnology Advances · doi:10.1016/j.biotechadv.2017.11.008 · Cited by 110

Genome editing for plant research and crop improvement

Zhan, X., Lu, Y., Zhu, J., & Botella, J. R. (2020) · Journal of Integrative Plant Biology · doi:10.1111/jipb.13063 · Cited by 121

Advances in Crop Breeding Through Precision Genome Editing

Nerkar, G., Devarumath, S., Purankar, M. V., Kumar, A., Valarmathi, R., Devarumath, R. M., & Appunu, C. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.880195 · Cited by 124

CRISPR/Cas9-mediated noncoding RNA editing in human cancers

Yang, J., Meng, X., Pan, J., Jiang, N., Zhou, C., Wu, Z., & Gong, Z. (2017) · RNA Biology · doi:10.1080/15476286.2017.1391443 · Cited by 122

Present and future prospects for wheat improvement through genome editing and advanced technologies

Li, S., Zhang, C., Li, J., Yan, L., Wang, N., & Xia, L. (2021) · Plant Communications · doi:10.1016/j.xplc.2021.100211 · Cited by 118

A CRISPR‐Cas9‐mediated domain‐specific base‐editing screen enables functional assessment of ACCase variants in rice

Liu, X., Qin, R., Li, J., Liao, S., Shan, T., Xu, R., Wu, D., & Wei, P. (2020) · Plant Biotechnology Journal · doi:10.1111/pbi.13348 · Cited by 116

CRISPR/Cas genome editing in tomato improvement: Advances and applications

Tiwari, J. K., Singh, A. K., & Behera, T. K. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2023.1121209 · Cited by 120

CRISPR/Cas9: Development and Application in Rice Breeding

Romero, F. M., & Gatica-Arias, A. (2019) · Rice Science · doi:10.1016/j.rsci.2019.08.001 · Cited by 118

Genome editing for horticultural crop improvement

Xu, J., Hua, K., & Lang, Z. (2019) · Horticulture Research · doi:10.1038/s41438-019-0196-5 · Cited by 117

Carotenoid biofortification in crop plants: citius, altius, fortius

Zheng, X., Giuliano, G., & Al‐Babili, S. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2020.158664 · Cited by 116

Genome Editing Technologies for Rice Improvement: Progress, Prospects, and Safety Concerns

Zafar, K., Sedeek, K. E. M., Rao, G. S., Khan, M. Z., Amin, I. U., Kamel, R., Mukhtar, Z., Zafar, M., Mansoor, S., & Mahfouz, M. M. (2020) · Frontiers in Genome Editing · doi:10.3389/fgeed.2020.00005 · Cited by 113

Editing the Genome Without Double-Stranded DNA Breaks

Komor, A. C., Badran, A. H., & Liu, D. R. (2017) · ACS Chemical Biology · doi:10.1021/acschembio.7b00710 · Cited by 112

Targeted Base Editing with CRISPR-Deaminase in Tomato

Shimatani, Z., Ariizumi, T., Fujikura, U., Kondo, A., Ezura, H., & Nishida, K. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-8991-1_22 · Cited by 10

Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion

Li, C., Zong, Y., Wang, Y., Jin, S., Zhang, D., Song, Q., Zhang, R., & Gao, C. (2018) · Genome biology · doi:10.1186/s13059-018-1443-z · Cited by 507

Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion

Zong, Y., Wang, Y., Li, C., Zhang, R., Chen, K., Ran, Y., Qiu, J., Wang, D., & Gao, C. (2017) · Nature Biotechnology · doi:10.1038/nbt.3811 · Cited by 896

CRISPR-Cas-Mediated Single Base Editing at More than One Locus in Rice Genome

Molla, K. A., & Yang, Y. (2020) · Springer protocols handbooks/Springer protocols · doi:10.1007/978-1-0716-0616-2_4 · Cited by 6

Inheritance of co-edited genes by CRISPR-based targeted nucleotide substitutions in rice

Shimatani, Z., Fujikura, U., Ishii, H., Matsui, Y., Suzuki, M., Ueke, Y., Taoka, K.-I., Terada, R., Nishida, K., & Kondo, A. (2018) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2018.04.028 · Cited by 44