The cancer genome atlas pan-cancer analysis project

The Cancer Genome Atlas Research Network, Weinstein, John N, Collisson, Eric A, Mills, Gordon B, Shaw, Kenna R Mills, Ozenberger, Brad A, Ellrott, Kyle, Shmulevich, Ilya +2 more·2013·Nature Genetics

Cited by (162)

Items 101–162 of 162

  1. Group lasso regularized deep learning for cancer prognosis from multi-omics and clinical features
    Xie, Gangcai, Dong, Chengliang, Kong, Yinfei, Zhong, Jiang F., Li, Mingyao, Wang, Kai · 2019 · Genes
  2. Application of a neural network whole transcriptome-based pan-cancer method for diagnosis of primary and metastatic cancers
    Grewal, Jasleen K., Tessier-Cloutier, Basile, Jones, Martin, Gakkhar, Sitanshu, Ma, Yussanne, Moore, Richard, Mungall, Andrew J., Zhao, Yongjun, Taylor, Michael D., Gelmon, Karen et al. · 2019 · JAMA Network Open
  3. A Six‐Stage Workflow for Robust Application of Systems Pharmacology
    Gadkar, K, Kirouac, DC, Mager, DE, van der Graaf, PH, Ramanujan, S · 2016 · CPT: Pharmacometrics & Systems Pharmacology
  4. Representation Learning of Histopathology Images using Graph Neural Networks
    Adnan, Mohammed, Kalra, Shivam, Tizhoosh, Hamid R. · 2020 · 2020 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW)
  5. Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network
    Haupt, Sue, Caramia, Franco, Herschtal, Alan, Soussi, Thierry, Lozano, Guillermina, Chen, Hu, Liang, Han, Speed, Terence P., Haupt, Ygal · 2019 · Nature Communications
  6. Integrated multi-omics analysis using variational autoencoders: Application to Pan-cancer Classification
    Zhang, Xiaoyu, Zhang, Jingqing, Sun, Kai, Yang, Xian, Dai, Chengliang, Guo, Yike · 2019 · 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
  7. Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes
    Zhou, Joseph X., Taramelli, Roberto, Pedrini, Edoardo, Knijnenburg, Theo, Huang, Sui · 2017 · Scientific Reports
  8. Predicting and characterizing a cancer dependency map of tumors with deep learning
    Chiu, Yu-Chiao, Zheng, Siyuan, Wang, Li-Ju, Iskra, Brian S., Rao, Manjeet K., Houghton, Peter J., Huang, Yufei, Chen, Yidong · 2021 · Science Advances
  9. Machine learning methods for histopathological image analysis: updates in 2024
    Komura, Daisuke, Ochi, Mieko, Ishikawa, Shumpei · 2025 · Computational and Structural Biotechnology Journal
  10. Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma
    Wang, Biao, Peng, Fu, Huang, Wei, Zhou, Jin, Zhang, Nan, Sheng, Jia, Haruehanroengra, Phensinee, He, Gu, Han, Bo · 2020 · Acta Pharmaceutica Sinica B
  11. Multiple Instance Captioning: Learning Representations from Histopathology Textbooks and Articles
    Gamper, Jevgenij, Rajpoot, Nasir · 2021 · 2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
  12. Characterization of frequently mutated cancer genes in Chinese breast tumors: a comparison of Chinese and TCGA cohorts
    Zhang, Guochun, Wang, Yulei, Chen, Bo, Guo, Liping, Cao, Li, Ren, Chongyang, Wen, Lingzhu, Li, Kai, Jia, Minghan, Li, Cheukfai et al. · 2019 · Annals of Translational Medicine
  13. PI4KIIIβ is a therapeutic target in chromosome 1q–amplified lung adenocarcinoma
    Tan, Xiaochao, Banerjee, Priyam, Pham, Edward A., Rutaganira, Florentine U. N., Basu, Kaustabh, Bota-Rabassedas, Neus, Guo, Hou-Fu, Grzeskowiak, Caitlin L., Liu, Xin, Yu, Jiang et al. · 2020 · Science Translational Medicine
  14. Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability
    Jäkel, Cornelia, Bergmann, Frank, Toth, Reka, Assenov, Yassen, van der Duin, Daniel, Strobel, Oliver, Hank, Thomas, Klöppel, Günter, Dorrell, Craig, Grompe, Markus et al. · 2017 · Nature Communications
  15. Acetylation targeting chimera enables acetylation of the tumor suppressor p53
    Kabir, Md, Sun, Ning, Hu, Xiaoping, Martin, Tiphaine C., Yi, Jingjie, Zhong, Yue, Xiong, Yan, Kaniskan, H. Ümit, Gu, Wei, Parsons, Ramon et al. · 2023 · Journal of the American Chemical Society
  16. PINA 3.0: mining cancer interactome
    Du, Yang, Cai, Meng, Xing, Xiaofang, Ji, Jiafu, Yang, Ence, Wu, Jianmin · 2021 · Nucleic Acids Research
  17. Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1
    Obiedat, Akram, Seidel, Einat, Mahameed, Mohamed, Bernani, Orit, Tsukerman, Pinchas, Voutetakis, Konstantinos, Chatziioannou, Aristotelis, Mcmahon, Mari, Avril, Tony, Chevet, Eric et al. · 2019 · The FASEB Journal
  18. A Multimodal Knowledge-enhanced Whole-slide Pathology Foundation Model
    Xu, Yingxue, Wang, Yihui, Zhou, Fengtao, Ma, Jiabo, Jin, Cheng, Yang, Shu, Li, Jinbang, Zhang, Zhengyu, Zhao, Chenglong, Zhou, Huajun et al. · 2024 · arXiv
  19. A weighted exact test for mutually exclusive mutations in cancer
    Leiserson, Mark DM, Reyna, Matthew A, Raphael, Benjamin J · 2016 · Bioinformatics
  20. Frequent mutations in acetylation and ubiquitination sites suggest novel driver mechanisms of cancer
    Narayan, Soumil, Bader, Gary D., Reimand, Jüri · 2016 · Genome Medicine
  21. Genomics and the Immune Landscape of Osteosarcoma
    Wu, Chia-Chin, Livingston, J. Andrew · 2020 · Advances in Experimental Medicine and Biology
  22. The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis
    Pinkney, Holly R., Wright, Brandon M., Diermeier, Sarah D. · 2020 · Non-Coding RNA
  23. Lessons Learned from Designing an AI-Enabled Diagnosis Tool for Pathologists
    Gu, Hongyan, Huang, Jingbin, Hung, Lauren, Chen, Xiang 'Anthony' · 2021 · Proceedings of the ACM on Human-Computer Interaction
  24. Tree-based machine learning algorithms identified minimal set of miRNA biomarkers for breast cancer diagnosis and molecular subtyping
    Sherafatian, Masih · 2018 · Gene
  25. Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain
    Wingo, Thomas S., Duong, Duc M., Zhou, Maotian, Dammer, Eric B., Wu, Hao, Cutler, David J., Lah, James J., Levey, Allan I., Seyfried, Nicholas T. · 2017 · Journal of Proteome Research
  26. Review of multi-omics data resources and integrative analysis for human brain disorders
    Dong, Xianjun, Liu, Chunyu, Dozmorov, Mikhail · 2021 · Briefings in Functional Genomics
  27. Comprehensive pharmacogenomic characterization of gastric cancer
    Sa, Jason K., Hong, Jung Yong, Lee, In-Kyoung, Kim, Ju-sun, Sim, Moon-Hee, Kim, Ha Jung, An, Ji Yeong, Sohn, Tae Sung, Lee, Joon Ho, Bae, Jae Moon et al. · 2020 · Genome Medicine
  28. Integrating healthcare and research genetic data empowers the discovery of 28 novel developmental disorders
    Kaplanis, Joanna, Samocha, Kaitlin E., Wiel, Laurens, Zhang, Zhancheng, Arvai, Kevin J., Eberhardt, Ruth Y., Gallone, Giuseppe, Lelieveld, Stefan H., Martin, Hilary C., McRae, Jeremy F. et al. · 2019
  29. A scoping review of robustness concepts for machine learning in healthcare
    Balendran, Alan, Beji, Céline, Bouvier, Florie, Khalifa, Ottavio, Evgeniou, Theodoros, Ravaud, Philippe, Porcher, Raphaël · 2025 · npj Digital Medicine
  30. Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status
    Patyka, Mariia, Sharifi, Zeinab, Petrecca, Kevin, Mansure, Jose, Jean-Claude, Bertrand, Sabri, Siham · 2016 · Oncotarget
  31. Prediction of Genetic Interactions Using Machine Learning and Network Properties
    Madhukar, Neel S., Elemento, Olivier, Pandey, Gaurav · 2015 · Frontiers in Bioengineering and Biotechnology
  32. Proteogenomics: emergence and promise
    Faulkner, Sam, Dun, Matthew D., Hondermarck, Hubert · 2015 · Cellular and Molecular Life Sciences
  33. Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders
    Schadt, Eric E., Buchanan, Sean, Brennand, Kristen J., Merchant, Kalpana M. · 2014 · Frontiers in Pharmacology
  34. Generation of synthetic whole-slide image tiles of tumours from RNA-sequencing data via cascaded diffusion models
    Carrillo-Perez, Francisco, Pizurica, Marija, Zheng, Yuanning, Nandi, Tarak Nath, Madduri, Ravi, Shen, Jeanne, Gevaert, Olivier · 2024 · Nature Biomedical Engineering
  35. <scp>AI</scp> in microbiome‐related healthcare
    Probul, Niklas, Huang, Zihua, Saak, Christina Caroline, Baumbach, Jan, List, Markus · 2024 · Microbial Biotechnology
  36. National Cancer Institute Imaging Data Commons: Toward Transparency, Reproducibility, and Scalability in Imaging Artificial Intelligence
    Fedorov, Andrey, Longabaugh, William J. R., Pot, David, Clunie, David A., Pieper, Steven D., Gibbs, David L., Bridge, Christopher, Herrmann, Markus D., Homeyer, André, Lewis, Rob et al. · 2023 · Radiographics
  37. Generating dermatopathology reports from gigapixel whole slide images with HistoGPT
    Tran, Manuel, Schmidle, Paul, Guo, Ruifeng Ray, Wagner, Sophia J., Koch, Valentin, Lupperger, Valerio, Novotny, Brenna, Murphree, Dennis H., Hardway, Heather D., D’Amato, Marina et al. · 2025 · Nature Communications
  38. Deep learning prediction of chemical-induced dose-dependent and context-specific multiplex phenotype responses and its application to personalized alzheimer’s disease drug repurposing
    Wu, You, Liu, Qiao, Qiu, Yue, Xie, Lei · 2022 · PLOS Computational Biology
  39. Signatures of evolutionary adaptation in quantitative trait loci influencing trace element homeostasis in liver
    Engelken, Johannes, Espadas, Guadalupe, Mancuso, Francesco M., Bonet, Nuria, Scherr, Anna-Lena, Jímenez-Álvarez, Victoria, Codina-Solà, Marta, Medina-Stacey, Daniel, Spataro, Nino, Stoneking, Mark et al. · 2016 · Molecular Biology and Evolution
  40. Computed cancer interactome explains the effects of somatic mutations in cancers
    Zhang, Jing, Pei, Jimin, Durham, Jesse, Bos, Tasia, Cong, Qian · 2022 · Protein Science
  41. Computational estimation of quality and clinical relevance of cancer cell lines
    Trastulla, Lucia, Noorbakhsh, Javad, Vazquez, Francisca, McFarland, James, Iorio, Francesco · 2022 · Molecular Systems Biology
  42. Role of AI in empowering and redefining the oncology care landscape: perspective from a developing nation
    Goel, Isha, Bhaskar, Yogendra, Kumar, Nand, Singh, Sunil, Amanullah, Mohammed, Dhar, Ruby, Karmakar, Subhradip · 2025 · Frontiers in Digital Health
  43. Giga-SSL: Self-Supervised Learning for Gigapixel Images
    Lazard, Tristan, Lerousseau, Marvin, Decencière, Etienne, Walter, Thomas · 2023 · 2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW)
  44. CRISPR Screening Identifies Mechanisms of Resistance to KRASG12C and SHP2 Inhibitor Combinations in Non-Small Cell Lung Cancer
    Prahallad, Anirudh, Weiss, Andreas, Voshol, Hans, Kerr, Grainne, Sprouffske, Kathleen, Yuan, Tina, Ruddy, David, Meistertzheim, Morgane, Kazic-Legueux, Malika, Kottarathil, Tina et al. · 2023 · Cancer Research
  45. Single-Cell RNA Sequencing for Studying Human Cancers
    Aran, Dvir · 2023 · Annual Review of Biomedical Data Science
  46. One label is all you need: Interpretable AI-enhanced histopathology for oncology
    Tavolara, Thomas E., Su, Ziyu, Gurcan, Metin N., Niazi, M. Khalid Khan · 2023 · Seminars in Cancer Biology
  47. Emerging proteomics biomarkers and prostate cancer burden in Africa
    Adeola, Henry A., Blackburn, Jonathan M., Rebbeck, Timothy R., Zerbini, Luiz F. · 2017 · Oncotarget
  48. Deep computational analysis details dysregulation of eukaryotic translation initiation complex eIF4F in human cancers
    Wu, Su, Wagner, Gerhard · 2021 · Cell Systems
  49. Bidimensional linked matrix factorization for pan-omics pan-cancer analysis
    Lock, Eric F., Park, Jun Young, Hoadley, Katherine A. · 2022 · The Annals of Applied Statistics
  50. Cancer-Associated Fibroblast Proteins as Potential Targets against Colorectal Cancers
    Shah, Ruchi, Johnson, Katherine A., Lippert, Anna E. L., Kraus, Sean G., Emmerich, Philip B., Pasch, Cheri A., Zhang, Wei, Matkowskyj, Kristina A., LeBeau, Aaron M., Deming, Dustin A. · 2024 · Cancers
  51. Assessing reproducibility and veracity across machine learning techniques in biomedicine: A case study using TCGA data
    Kim, Ahyoung Amy, Rachid Zaim, Samir, Subbian, Vignesh · 2020 · International Journal of Medical Informatics
  52. Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis
    Lim, Bryce, Kamal, Aryan, Gomez Ramos, Borja, Adrian Segarra, Juan M., Ibarra, Ignacio L., Dignas, Lennart, Kindinger, Tim, Volz, Kai, Rahbari, Mohammad, Rahbari, Nuh et al. · 2025 · Nature Genetics
  53. Deep Learning for Integrated Analysis of Breast Cancer Subtype Specific Multi-omics Data
    Rakshit, Somnath, Saha, Indrajit, Chakraborty, Subha Shankar, Plewczyski, Dariusz · 2018 · TENCON 2018 - 2018 IEEE Region 10 Conference
  54. The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database
    Elbers, Danne C., Fillmore, Nathanael R., Sung, Feng-Chi, Ganas, Spyridon S., Prokhorenkov, Andrew, Meyer, Christopher, Hall, Robert B., Ajjarapu, Samuel J., Chen, Daniel C., Meng, Frank et al. · 2020 · Patterns
  55. WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer
    Yamamoto, Gaku, Tanaka, Kosuke, Kamata, Ryo, Saito, Hitoshi, Yamamori-Morita, Tomoko, Nakao, Takehiro, Liu, Jie, Mori, Shunta, Yagishita, Shigehiro, Hamada, Akinobu et al. · 2025 · Cancer Letters
  56. Histopathology Slide Indexing and Search — Are We There Yet?
    Shang, Helen H., Nasr, Mohammad Sadegh, Veerla, Jai Prakash, Saurav, Jillur Rahman, Hajighasemi, Amir, Malidarreh, Parisa, Huber, Manfred, Moleta, Chace, Makker, Jitin, Luber, Jacob M. · 2024 · NEJM AI
  57. Model‐Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers
    Kirouac, DC, Lahdenranta, J, Du, J, Yarar, D, Onsum, MD, Nielsen, UB, McDonagh, CF · 2015 · CPT: Pharmacometrics &amp; Systems Pharmacology
  58. SetQuence &amp; SetOmic: Deep Set Transformer-based Representations of Cancer Multi-Omics
    Jurenaite, Neringa, León-Periñán, Daniel, Donath, Veronika, Torge, Sunna, Jäkel, René · 2022 · 2022 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB)
  59. CDK19 is a Regulator of Triple-Negative Breast Cancer Growth
    Hsieh, Robert W., Kuo, Angera H., Scheeren, Ferenc A., Zarnegar, Mark A., Sikandar, Shaheen S., Antony, Jane, Heitink, Luuk S., Periyakoil, Divya, Kalisky, Tomer, Sim, Sopheak et al. · 2018
  60. A Tumour-Specific Molecular Network Promotes Tumour Growth in <i>Drosophila</i> by Enforcing a JNK-YKI Feedforward Loop
    Waghmare, Indrayani, Gangwani, Karishma, Rai, Arushi, Singh, Amit, Kango-Singh, Madhuri · 2023
  61. VPS34 in Autophagy, Cancer and Cancer Therapy
    Bartolini, Elisabetta, Janji, Bassam, Gao, Ruize · 2026
  62. EG-BINN: Parameter-Efficient Ensembling of Gated Biologically Informed Neural Networks for Epigenetic Age Estimation
    Edwards, Travyse, Long, Qi, Shen, Li · 2026