The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer’s Disease

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

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A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

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Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

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Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

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Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

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Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

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Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

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Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

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<i>TREM2</i> Variants in Alzheimer's Disease

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The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

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Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

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Apolipoprotein E: Far More Than a Lipid Transport Protein

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TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

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Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

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Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

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Distinct patterns of brain activity in young carriers of the <i>APOE</i> -ε4 allele

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The microglial sensome revealed by direct RNA sequencing

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An english translation of alzheimer’s 1907 paper, “über eine eigenartige erkankung der hirnrinde”

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Normal aging induces A1-like astrocyte reactivity

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ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

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APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

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Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

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TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia

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Microglia in Alzheimer's disease

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Adult mouse astrocytes degrade amyloid-β in vitro and in situ

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Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

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Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system.

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Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

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apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

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Regional aerobic glycolysis in the human brain

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Sweet Sixteen for ANLS

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The aging astrocyte transcriptome from multiple regions of the mouse brain.

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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

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Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

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Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

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Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

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Apolipoprotein E structure: insights into function

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Microglia-Astrocyte Crosstalk: An Intimate Molecular Conversation

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Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease

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Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis

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In vivo evidence for a lactate gradient from astrocytes to neurons

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Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides

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ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

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The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

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Mechanisms of Aβ Clearance and Degradation by Glial Cells

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Profile and Regulation of Apolipoprotein E (ApoE) Expression in the CNS in Mice with Targeting of Green Fluorescent Protein Gene to the ApoE Locus

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Central Nervous System Lipoproteins: ApoE and Regulation of Cholesterol Metabolism

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Glycogen synthase kinase 3: more than a namesake

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A transcriptomic atlas of aged human microglia

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Brain lactate metabolism: the discoveries and the controversies

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Lactate Produced by Glycogenolysis in Astrocytes Regulates Memory Processing

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Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

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A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

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Neuron-Specific Apolipoprotein E4 Proteolysis Is Associated with Increased Tau Phosphorylation in Brains of Transgenic Mice

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APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response

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Isolation of glia from Alzheimer’s mice reveals inflammation and dysfunction

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Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer’s Disease Risk Factors in Yeast

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Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy

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Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter

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Conditional Disruption of the Peroxisome Proliferator-Activated Receptor γ Gene in Mice Results in Lowered Expression of ABCA1, ABCG1, and apoE in Macrophages and Reduced Cholesterol Efflux

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APOE genotype-specific differences in the innate immune response

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Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor-γ-Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease

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Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

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PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease

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Apo E structure determines VLDL clearance and atherosclerosis risk in mice

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Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

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Transitions in metabolic and immune systems from pre-menopause to post-menopause: implications for age-associated neurodegenerative diseases

Wang, Y., Mishra, A., & Brinton, R. D. (2020) · F1000Research · doi:10.12688/f1000research.21599.1 · Cited by 63 · see citing works

The Role of Butyrylcholinesterase and Iron in the Regulation of Cholinergic Network and Cognitive Dysfunction in Alzheimer’s Disease Pathogenesis

Jasiecki, J., Targońska, M., & Wasąg, B. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042033 · Cited by 64 · see citing works

Role of Neuron and Glia in Alzheimer’s Disease and Associated Vascular Dysfunction

Bandyopadhyay, S. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.653334 · Cited by 62 · see citing works

Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice

Larramona-Arcas, R., González-Arias, C., Perea, G., Gutiérrez, A., Vitorica, J., García-Barrera, T., Gómez-Ariza, J. L., Pascua-Maestro, R., Ganfornina, M. D., Kara, E., et al. (2020) · Molecular Neurodegeneration · doi:10.1186/s13024-020-00382-8 · Cited by 56 · see citing works

The role of DHCR24 in the pathogenesis of AD: re-cognition of the relationship between cholesterol and AD pathogenesis

Bai, X., Mai, M., Yao, K., Zhang, M., Huang, Y. M., Zhang, W., Guo, X., Xu, Y., Zhang, Y., Qurban, A., et al. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01338-3 · Cited by 56 · see citing works

Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro

Iannucci, J., Sen, A., & Grammas, P. (2021) · Current Issues in Molecular Biology · doi:10.3390/cimb43010018 · Cited by 55 · see citing works

ApoE4 attenuates autophagy via FoxO3a repression in the brain

Sohn, H.-Y., Kim, S.-I., Park, J.-Y., Park, S.-H., Koh, Y. H., Kim, J., & Jo, C. (2021) · Scientific Reports · doi:10.1038/s41598-021-97117-6 · Cited by 54 · see citing works

Molecular Insight into the Therapeutic Promise of TargetingAPOE4for Alzheimer’s Disease

Mamun, A. A., Uddin, M. S., Bashar, M. F. B., Zaman, S., Begum, Y., Bulbul, I. J., Islam, M. S., Sarwar, M. S., Mathew, B., Amran, M. S., et al. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/5086250 · Cited by 53 · see citing works

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

Jiang, Y., Zhou, X., Wong, H. Y., Ouyang, L., Ip, F. C. F., Chau, V. M. N., Lau, S., Wu, W., Wong, D. Y. K., Seo, H., et al. (2022) · Nature Aging · doi:10.1038/s43587-022-00241-9 · Cited by 53 · see citing works

Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases

Lizama, B. N., Kahle, J. S., Catalano, S. M., Caggiano, A. O., Grundman, M., & Hamby, M. E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076251 · Cited by 51 · see citing works

A practical application of generative adversarial networks for RNA-seq analysis to predict the molecular progress of Alzheimer's disease

Park, J., Kim, H., Kim, J., & Cheon, M. (2020) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1008099 · Cited by 50 · see citing works

Astrocytic Calcium and cAMP in Neurodegenerative Diseases

Sobolczyk, M., & Boczek, T. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.889939 · Cited by 50 · see citing works

Impact of sex and APOE ε4 on age-related cerebral perfusion trajectories in cognitively asymptomatic middle-aged and older adults: A longitudinal study

Wang, R., Oh, J. M., Motovylyak, A., Ma, Y., Sager, M. A., Rowley, H. A., Johnson, K. M., Gallagher, C. L., Carlsson, C. M., Bendlin, B. B., et al. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211021313 · Cited by 49 · see citing works

Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias

Yassine, H. N., Self, W. K., Kerman, B. E., Santoni, G., Shanmugam, N. K. N., Abdullah, L. I., Golden, L. R., Fonteh, A. N., Harrington, M. G., Gräff, J., et al. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12845 · Cited by 49 · see citing works

Associations of Omega-3 fatty acids with brain morphology and volume in cognitively healthy older adults: A narrative review

Macaron, T., Giudici, K. V., Bowman, G. L., Sinclair, A. J., Stephan, E., Vellas, B. J., & Barreto, P. D. S. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101300 · Cited by 49 · see citing works

Redefining transcriptional regulation of the APOE gene and its association with Alzheimer’s disease

Lee, E.-G., Tulloch, J., Chen, S., Leong, L., Saxton, A. D., Kraemer, B. C., Darvas, M., Keene, C. D., Shutes‐David, A., Todd, K. W., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0227667 · Cited by 46 · see citing works

ApoE4 activates C/EBPβ/δ-secretase with 27-hydroxycholesterol, driving the pathogenesis of Alzheimer’s disease

Wang, Z.-H., Xia, Y., Liu, P., Liu, X., Edgington‐Mitchell, L. E., Lei, K., Yu, S. P., Wang, X., & Ye, K. (2021) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2021.102032 · Cited by 48 · see citing works

Neuronal ApoE4 stimulates C/EBPβ activation, promoting Alzheimer’s disease pathology in a mouse model

Wang, Z.-H., Xia, Y., Wu, Z., Kang, S. S., Zhang, J.-C., Liu, P., Liu, X., Song, W., Huin, V., Dhaenens, C., et al. (2021) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2021.102212 · Cited by 47 · see citing works

Oxidative Stress: Pathological Driver in Chronic Neurodegenerative Diseases

Chong, Z. Z., & Souayah, N. (2025) · Antioxidants · doi:10.3390/antiox14060696 · Cited by 50 · see citing works

Associations between Alzheimer’s disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participants

Foo, H., Thalamuthu, A., Jiang, J., Koch, F. C., Mather, K. A., Wen, W. X., & Sachdev, P. S. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.11.002 · Cited by 46 · see citing works

Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid precursor protein, secretases, and cholesterol

Rudajev, V., & Novotný, J. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01127-y · Cited by 47 · see citing works

Mercury and Alzheimer’s disease: a look at the links and evidence

Azar, J., Yousef, M. H., El‐Fawal, H. A. N., & Abdelnaser, A. (2021) · Metabolic Brain Disease · doi:10.1007/s11011-020-00649-5 · Cited by 44 · see citing works

The effect of aged microglia on synaptic impairment and its relevance in neurodegenerative diseases

Triviño, J. J., & von Bernhardi, R. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.104982 · Cited by 43 · see citing works

HDL-like-Mediated Cell Cholesterol Trafficking in the Central Nervous System and Alzheimer’s Disease Pathogenesis

Borràs, C., Mercer, A., Sirisi, S., Alcolea, D. A., Escolá‐Gil, J. C., Blanco‐Vaca, F., & Tondo, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169356 · Cited by 41 · see citing works

Cellular senescence and the blood–brain barrier: Implications for aging and age-related diseases

Knopp, R. C., Erickson, M. A., Rhea, E. M., Reed, M. J., & Banks, W. A. (2023) · Experimental Biology and Medicine · doi:10.1177/15353702231157917 · Cited by 44 · see citing works

Roles of TREM2 in the Pathological Mechanism and the Therapeutic Strategies of Alzheimer's Disease

Lin, M., Yu, J., Zhang, W., Lao, F., & Huang, H. (2024) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2024.164 · Cited by 41 · see citing works

Multi-functional role of apolipoprotein E in neurodegenerative diseases

Islam, S., Noorani, A. A., Sun, Y., Michikawa, M., & Zou, K. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1535280 · Cited by 41 · see citing works

Interplay Between Microglia and Alzheimer’s Disease—Focus on the Most Relevant Risks: APOE Genotype, Sex and Age

Chen, Y., Hong, T., Chen, F., Sun, Y., Wang, Y., & Cui, L. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.631827 · Cited by 39 · see citing works

Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease

Dehghan, A., Pinto, R. C., Karaman, İ., Huang, J. V., Durainayagam, B. R., Ghanbari, M., Nazeer, A., Zhong, Q., Liggi, S., Whiley, L., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2206083119 · Cited by 38 · see citing works

Synapses, Microglia, and Lipids in Alzheimer’s Disease

Paasila, P. J., Aramideh, J. A., Sutherland, G. T., & Graeber, M. B. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.778822 · Cited by 38 · see citing works

Comprehensive Overview of Alzheimer’s Disease: Etiological Insights and Degradation Strategies

Singh, M. K., Shin, Y., Ju, S., Han, S., Kim, S. S., & Kang, I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25136901 · Cited by 41 · see citing works

Regulation of Synaptic Development by Astrocyte Signaling Factors and Their Emerging Roles in Substance Abuse

Walker, C. D., Risher, W. C., & Risher, M. (2020) · Cells · doi:10.3390/cells9020297 · Cited by 36 · see citing works

Autocrine Effects of Brain Endothelial Cell-Produced Human Apolipoprotein E on Metabolism and Inflammation in vitro

Marottoli, F. M., Trevino, T. N., Geng, X. H., Arbieva, Z. H., Kanabar, P. N., Maienschein‐Cline, M., Lee, J. C., Lutz, S. E., & Tai, L. M. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.668296 · Cited by 38 · see citing works

Repurposing Immunomodulatory Imide Drugs (IMiDs) in Neuropsychiatric and Neurodegenerative Disorders

Jung, Y. J., Tweedie, D., Scerba, M. T., Kim, D. S., Palmas, M. F., Pisanu, A., Carta, A. R., & Greig, N. H. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.656921 · Cited by 36 · see citing works

Pathogens Hijack Host Cell Metabolism: Intracellular Infection as a Driver of the Warburg Effect in Cancer and Other Chronic Inflammatory Conditions

Proal, A. D., & VanElzakker, M. B. (2020) · Immunometabolism · doi:10.20900/immunometab20210003 · Cited by 35 · see citing works

NOX-induced oxidative stress is a primary trigger of major neurodegenerative disorders

Zilberter, Y., Tabuena, D. R., & Zilberter, M. Y. (2023) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2023.102539 · Cited by 34 · see citing works

APOE4 genetic polymorphism results in impaired recovery in a repeated mild traumatic brain injury model and treatment with Bryostatin-1 improves outcomes

Giarratana, A. O., Zheng, C., Reddi, S., Teng, S. L., Berger, D. S., Adler, D., Sullivan, P. M., Thakker‐Varia, S., & Alder, J. (2020) · Scientific Reports · doi:10.1038/s41598-020-76849-x · Cited by 33 · see citing works

Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

Fote, G., Geller, N. R., Efstathiou, N. E., Hendricks, N. G., Vavvas, D. G., Reidling, J. C., Thompson, L. M., & Steffan, J. S. (2022) · Journal of Cell Science · doi:10.1242/jcs.258687 · Cited by 33 · see citing works

Air pollution exposure during pregnancy and childhood, APOE ε4 status and Alzheimer polygenic risk score, and brain structural morphology in preadolescents

Essers, E., Binter, A.-C., Neumann, A., White, T. J. H., Alemany, S., & Guxens, M. (2022) · Environmental Research · doi:10.1016/j.envres.2022.114595 · Cited by 32 · see citing works

Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The Impact of HDL-Cholesterol and Ceramides

Sergi, D., Zauli, E., Tisato, V., Secchiero, P., Zauli, G., & Cervellati, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054403 · Cited by 32 · see citing works

Can SARS-CoV-2 Infection Exacerbate Alzheimer’s Disease? An Overview of Shared Risk Factors and Pathogenetic Mechanisms

Villa, C., Rivellini, E., Lavitrano, M., & Combi, R. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12010029 · Cited by 32 · see citing works

Alzheimer’s disease: a tale of two diseases?

Nardini, E., Hogan, R., Flamier, A., & Bernier, G. (2021) · Neural Regeneration Research · doi:10.4103/1673-5374.308070 · Cited by 30 · see citing works

Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer’s Disease Risk

Eid, A., Mhatre‐Winters, I., Sammoura, F. M., Edler, M. K., von Stein, R., Hossain, M. M., Han, Y., Lisci, M., Carney, K., Konsolaki, M., et al. (2022) · Environmental Health Perspectives · doi:10.1289/ehp10576 · Cited by 30 · see citing works

Nanomedicine based strategies for oligonucleotide traversion across the blood–brain barrier

Amulya, E., Sikder, A., Vambhurkar, G. B., Shah, S., Khatri, D. K., Raghuvanshi, R. S., Singh, S. B., & Srivastava, S. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.01.031 · Cited by 30 · see citing works

Role of TET1-mediated epigenetic modulation in Alzheimer's disease

Armstrong, M. J., Jin, Y., Vattathil, S., Huang, Y., Schroeder, J. P., Bennet, D. A., Qin, Z. S., Wingo, T. S., & Jin, P. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106257 · Cited by 30 · see citing works

CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers

Ahmad, S., Milan, M. D. C., Hansson, O., Demirkan, A., Agustin, R., Sáez, M. E., Giagtzoglou, N., Cabrera-Socorro, A., Bakker, M. H. M., Ramirez, A., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-65038-5 · Cited by 31 · see citing works

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases

Trudler, D., Ghatak, S., & Lipton, S. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158196 · Cited by 30 · see citing works

Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired <i>APOE</i> ε4 homozygotes

Riviere, M., Langbaum, J. B., Turner, R. S., Rinne, J. O., Sui, Y., Cazorla, P., Ricart, J., Meneses, K., Caputo, A., Tariot, P. N., et al. (2024) · Alzheimer's &amp; Dementia · doi:10.1002/alz.13532 · Cited by 28 · see citing works

Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways

Xu, D. C., Sas‐Nowosielska, H., Donahue, G., Huang, H., Pourshafie, N., Good, C. R., & Berger, S. L. (2024) · Acta Neuropathologica Communications · doi:10.1186/s40478-023-01696-6 · Cited by 30 · see citing works

How does apolipoprotein E genotype influence the relationship between physical activity and Alzheimer’s disease risk? A novel integrative model

de Frutos‐Lucas, J., Sewell, K. R., García‐Colomo, A., Markovic, S. J., Erickson, K. I., & Brown, B. M. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01170-4 · Cited by 26 · see citing works

Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice

Mhatre‐Winters, I., Eid, A., Han, Y., Tieu, K., & Richardson, J. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179829 · Cited by 26 · see citing works

Associations of urinary 8‐iso‐prostaglandin F2α levels with all‐cause dementia, Alzheimer's disease, and vascular dementia incidence: results from a prospective cohort study

Trares, K., Gao, X. Y., Perna, L., Rujescu, D., Stocker, H. R., Möllers, T., Beyreuther, K. T., Brenner, H., & Schöttker, B. (2020) · Alzheimer s & Dementia · doi:10.1002/alz.12081 · Cited by 26 · see citing works

A systems biology approach for studying neurodegenerative diseases

Lam, S. C. C., Bayraktar, A., Zhang, C., Türkez, H., Nielsen, J., Borén, J., Shoaie, S., Uhlén, M., & Mardinoğlu, A. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.05.010 · Cited by 24 · see citing works

Microfluidic Platforms to Unravel Mysteries of Alzheimer’s Disease: How Far Have We Come?

Prasanna, P., Rathee, S., Rahul, V., Mandal, D., Goud, M. S. C., Yadav, P., Hawthorne, S. J., Sharma, A., Gupta, P. K., Ojha, S. K., et al. (2021) · Life · doi:10.3390/life11101022 · Cited by 24 · see citing works

Physiological and Pathological Ageing of Astrocytes in the Human Brain

Verkerke, M., Hol, E. M., & Middeldorp, J. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03256-7 · Cited by 49 · see citing works

From Genetics to Neuroinflammation: The Impact of ApoE4 on Microglial Function in Alzheimer’s Disease

Dias, D., Portugal, C. C., Relvas, J. B., & Socodato, R. (2025) · Cells · doi:10.3390/cells14040243 · Cited by 66 · see citing works

APOE4 Drives Impairment in Astrocyte-Neuron Coupling in Alzheimer's Disease and Works Through Mechanisms in Early Disease to Influence Pathology

Tumbleson, D. M. (2023) · Purdue University Indianapolis (Indiana University) · doi:10.7912/c2/3138

Microglial APOE4: more is less and less is more

Eskandari‐Sedighi, G., & Blurton-Jones, M. M. (2023) · Molecular Neurodegeneration · doi:10.1186/s13024-023-00693-6 · Cited by 11 · see citing works

The cell biology of APOE in the brain

Cohen, S., & Windham, I. A. (2025) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/4w7d-0v40