Stem cell therapy for human neurodegenerative disorders–how to make it work

Neurogenesis in the adult human hippocampus

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Neuronal replacement from endogenous precursors in the adult brain after stroke

Arvidsson, A., Collin, T., Kirik, D., Kokaia, Z., & Lindvall, O. (2002) · Nature Medicine · doi:10.1038/nm747 · Cited by 2,799

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426

Transplantation of Embryonic Dopamine Neurons for Severe Parkinson's Disease

Freed, C. R., Greene, P. E., Breeze, R. E., Tsai, W.-Y., DuMouchel, W., Kao, R., Dillon, S., Winfield, H., Culver, S., Trojanowski, J. Q., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200103083441002 · Cited by 2,366

Vascular niche for adult hippocampal neurogenesis

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Directed Differentiation of Embryonic Stem Cells into Motor Neurons

Wichterle, H., Lieberam, I., Porter, J. A., & Jessell, T. M. (2002) · Cell · doi:10.1016/s0092-8674(02)00835-8 · Cited by 1,728

Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

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Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease

Kim, J.-H., Auerbach, J. M., Rodríguez-Gómez, J. A., Velasco, I., Gavin, D., Lumelsky, N., Lee, S.-H., Nguyen, J., Sánchez-Pernaute, R., Bankiewicz, K., et al. (2002) · Nature · doi:10.1038/nature00900 · Cited by 1,607

Inflammation is detrimental for neurogenesis in adult brain

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Clonally Derived Human Embryonic Stem Cell Lines Maintain Pluripotency and Proliferative Potential for Prolonged Periods of Culture

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Astroglia induce neurogenesis from adult neural stem cells

Song, H., Stevens, C. F., & Gage, F. H. (2002) · Nature · doi:10.1038/417039a · Cited by 1,452

Regeneration of Hippocampal Pyramidal Neurons after Ischemic Brain Injury by Recruitment of Endogenous Neural Progenitors

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Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration

Sanai, N., Tramontin, A. D., Quiñones-Hinojosa, A., Barbaro, N. M., Gupta, N., Kunwar, S., Lawton, M. T., McDermott, M. W., Parsa, A. T., Manuel-García Verdugo, J., et al. (2004) · Nature · doi:10.1038/nature02301 · Cited by 1,313

A double‐blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

Olanow, C. W., Goetz, C. G., Kordower, J. H., Stoessl, A. J., Sossi, V., Brin, M. F., Shannon, K. M., Nauert, G. M., Perl, D. P., Godbold, J., et al. (2003) · Annals of Neurology · doi:10.1002/ana.10720 · Cited by 1,307

Induction of Midbrain Dopaminergic Neurons from ES Cells by Stromal Cell–Derived Inducing Activity

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Induction of neurogenesis in the neocortex of adult mice

Magavi, S. S., Leavitt, B. R., & Macklis, J. D. (2000) · Nature · doi:10.1038/35016083 · Cited by 1,216

VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

Sun, Y., Jin, K., Xie, L., Childs, J., Mao, X. O., Logvinova, A. V., & Greenberg, D. A. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17977 · Cited by 1,204

VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

Sun, Y., Jin, K., Xie, L., Childs, J., Mao, X. O., Logvinova, A., & Greenberg, D. A. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200317977 · Cited by 1,189

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

Björklund, L. M., Sánchez-Pernaute, R., Chung, S., Andersson, T., Chen, I. Y. C., McNaught, K. S. P., Brownell, A.-L., Jenkins, B. G., Wahlestedt, C., Kim, K.-S., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022438099 · Cited by 1,170

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

Pluchino, S., Quattrini, A., Brambilla, E., Gritti, A., Salani, G., Dina, G., Galli, R., Del Carro, U., Amadio, S., Bergami, A., et al. (2003) · Nature · doi:10.1038/nature01552 · Cited by 1,068

Deep brain stimulation for Parkinson’s disease

Benabid, A. L. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.11.001 · Cited by 1,046

Rat forebrain neurogenesis and striatal neuron replacement after focal stroke

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Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells

Draper, J. S., Smith, K., Gokhale, P., Moore, H. D., Maltby, E., Johnson, J., Meisner, L., Zwaka, T. P., Thomson, J. A., & Andrews, P. W. (2004) · Nature Biotechnology · doi:10.1038/nbt922 · Cited by 1,021

TRANSPLANTATION OF EMBRYONIC DOPAMINE NEURONS FOR SEVERE PARKINSON'S DISEASE

Reed, R., Reene, P. A. E. G., Reeze, R. O. E. B., Ei, W., Ouchel, W. I. D. U. M., Ao, R. I. K., Infield, W., Ulver, S. H. C., Rojanowski, J. O. Q. T., Idelberg, D. A. E., et al. (2001) · Cited by 1,001

Neuropathological Evidence of Graft Survival and Striatal Reinnervation after the Transplantation of Fetal Mesencephalic Tissue in a Patient with Parkinson's Disease

Kordower, J. H., Freeman, T. B., Snow, B. J., Vingerhoets, F. J. G., Mufson, E. J., Sanberg, P. R., Hauser, R. A., Smith, D. A., Nauert, G. M., Perl, D. P., et al. (1995) · New England Journal of Medicine · doi:10.1056/nejm199504273321702 · Cited by 860

Enhanced Proliferation, Survival, and Dopaminergic Differentiation of CNS Precursors in Lowered Oxygen

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Monitoring of implanted stem cell migration in vivo : A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat

Hoehn, M., Küstermann, E., Blunk, J., Wiedermann, D., Trapp, T., Wecker, S., Föcking, M., Arnold, H., Hescheler, J., Fleischmann, B. K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242435499 · Cited by 707

Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient

Piccini, P., Brooks, D. J., Björklund, A., Gunn, R. N., Grasby, P. M., Rimoldi, O., Brundin, P., Hagell, P., Rehncrona, S., Widner, H., et al. (1999) · Nature Neuroscience · doi:10.1038/16060 · Cited by 700

Homologous recombination in human embryonic stem cells

Zwaka, T. P., & Thomson, J. A. (2003) · Nature Biotechnology · doi:10.1038/nbt788 · Cited by 666

Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain

Nunes, M. C., Roy, N. S., Keyoung, H. M., Goodman, R. R., McKhann, G., Jiang, L., Kang, J., Nedergaard, M., & Goldman, S. A. (2003) · Nature Medicine · doi:10.1038/nm837 · Cited by 656

Erythropoietin Regulates the In Vitro and In Vivo Production of Neuronal Progenitors by Mammalian Forebrain Neural Stem Cells

Shingo, T., Sorokan, S. T., Shimazaki, T., & Weiss, S. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-24-09733.2001 · Cited by 653

Transplantation of cultured human neuronal cells for patients with stroke

Kondziolka, D., Wechsler, L., Goldstein, S., Meltzer, C., Thulborn, K. R., Gebel, J., Jannetta, P., DeCesare, S., Elder, E. M., McGrogan, M., et al. (2000) · Neurology · doi:10.1212/wnl.55.4.565 · Cited by 629

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice

Barberi, T., Klivenyi, P., Calingasan, N. Y., Lee, H., Kawamata, H., Loonam, K., Perrier, A. L., Bruses, J., Rubio, M. E., Topf, N., et al. (2003) · Nature Biotechnology · doi:10.1038/nbt870 · Cited by 623

Evidence for neurogenesis in the adult mammalian substantia nigra

Zhao, M., Momma, S., Delfani, K., Carlén, M., Cassidy, R. M., Johansson, C. B., Brismar, H., Shupliakov, O., Frisén, J., & Janson, A. M. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1131955100 · Cited by 590

Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia

Zhang, R. L., Zhang, Z. G., Zhang, L., & Chopp, M. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00117-8 · Cited by 576

Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC

Moon, L. D. F., Asher, R. A., Rhodes, K. E., & Fawcett, J. W. (2001) · Nature Neuroscience · doi:10.1038/87415 · Cited by 562

Site-Specific Migration and Neuronal Differentiation of Human Neural Progenitor Cells after Transplantation in the Adult Rat Brain

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The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue

Park, K. I., Teng, Y. D., & Snyder, E. Y. (2002) · Nature Biotechnology · doi:10.1038/nbt751 · Cited by 554

Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats

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Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain

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Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum

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Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons

Ourednik, J., Ourednik, V., Lynch, W. P., Schachner, M., & Snyder, E. Y. (2002) · Nature Biotechnology · doi:10.1038/nbt750 · Cited by 496

Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity

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Motor and cognitive improvements in patients with Huntington's disease after neural transplantation

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FGF-2 regulation of neurogenesis in adult hippocampus after brain injury

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Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant

Weimann, J. M., Johansson, C. B., Trejo, A., & Blau, H. M. (2003) · Nature Cell Biology · doi:10.1038/ncb1053 · Cited by 451

The Adult Substantia Nigra Contains Progenitor Cells with Neurogenic Potential

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Dyskinesias following neural transplantation in Parkinson's disease

Hagell, P., Piccini, P., Björklund, A., Brundin, P., Rehncrona, S., Widner, H., Crabb, L., Pavese, N., Oertel, W. H., Quinn, N., et al. (2002) · Nature Neuroscience · doi:10.1038/nn863 · Cited by 443

Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes

Wagner, J., Åkerud, P., Castro, D. S., Holm, P. C., Canals, J. M., Snyder, E. Y., Perlmann, T., & Arenas, E. (1999) · Nature Biotechnology · doi:10.1038/10862 · Cited by 370

Isolation of Lineage-Restricted Neuronal Precursors from Multipotent Neuroepithelial Stem Cells

Mayer-Proschel, M., Kalyani, A. J., Mujtaba, T., & Rao, M. S. (1997) · Neuron · doi:10.1016/s0896-6273(00)80960-5 · Cited by 369

Host-Dependent Tumorigenesis of Embryonic Stem Cell Transplantation in Experimental Stroke

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Neuroectodermal differentiation from mouse multipotent adult progenitor cells

Jiang, Y., Henderson, D., Blackstad, M., Chen, A., Miller, R. F., & Verfaillie, C. M. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1834196100 · Cited by 349

Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies

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Intravenous Administration of Human Umbilical Cord Blood Cells in a Mouse Model of Amyotrophic Lateral Sclerosis: Distribution, Migration, and Differentiation

Garbuzova-Davis, S., Willing, A. E., Zigova, T., Saporta, S., Justen, E. B., Lane, J. C., Hudson, J. E., Chen, N., Davis, C. D., & Sanberg, P. R. (2003) · Journal of Hematotherapy & Stem Cell Research · doi:10.1089/152581603322022990 · Cited by 308

Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease

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Neuroepithelial Stem Cells from the Embryonic Spinal Cord: Isolation, Characterization, and Clonal Analysis

Kalyani, A., Hobson, K., & Rao, M. S. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8592 · Cited by 295

Long-Term Proliferation and Dopaminergic Differentiation of Human Mesencephalic Neural Precursor Cells

Storch, A., Paul, G., Csete, M., Boehm, B. O., Carvey, P. M., Kupsch, A., & Schwarz, J. (2001) · Experimental Neurology · doi:10.1006/exnr.2001.7706 · Cited by 273

Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

Li, Y., Chen, J., Wang, L., Zhang, L., Lu, M., & Chopp, M. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)02384-9 · Cited by 271

Transplanted fetal striatum in Huntington's disease: Phenotypic development and lack of pathology

Freeman, T. B., Cicchetti, F., Hauser, R. A., Deacon, T. W., Li, X.-J., Hersch, S. M., Nauert, G. M., Sanberg, P. R., Kordower, J. H., Saporta, S., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.25.13877 · Cited by 267

Stem cell factor stimulates neurogenesis in vitro and in vivo

Jin, K., Mao, X. O., Sun, Y., Xie, L., & Greenberg, D. A. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15251 · Cited by 263

Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts

Piccini, P., Lindvall, O., Bj�rklund, A., Brundin, P., Hagell, P., Ceravolo, R., Oertel, W., Quinn, N., Samuel, M., Rehncrona, S., et al. (2000) · Annals of Neurology · doi:10.1002/1531-8249(200011)48:5<689::aid-ana1>3.0.co;2-n · Cited by 255

Human Embryonic Germ Cell Derivatives Facilitate Motor Recovery of Rats with Diffuse Motor Neuron Injury

Kerr, D. A., Lladó, J., Shamblott, M. J., Maragakis, N. J., Irani, D. N., Crawford, T. O., Krishnan, C., Dike, S., Gearhart, J. D., & Rothstein, J. D. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-12-05131.2003 · Cited by 251

Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons

Chung, S., Sonntag, K., Andersson, T., Bjorklund, L. M., Park, J., Kim, D., Kang, U. J., Isacson, O., & Kim, K. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02255.x · Cited by 250

Bilateral human fetal striatal transplantation in Huntington’s disease

Hauser, R. A., Furtado, S., Cimino, C. R., Delgado, H., Eichler, S., Schwartz, S., Scott, D., Nauert, G. M., Soety, E., Sossi, V., et al. (2002) · Neurology · doi:10.1212/wnl.58.5.687 · Cited by 245

Clonal Human (hNT) Neuron Grafts for Stroke Therapy

Nelson, P. T., Kondziolka, D., Wechsler, L., Goldstein, S., Gebel, J., DeCesare, S., Elder, E. M., Zhang, P. J., Jacobs, A., McGrogan, M., et al. (2002) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)62546-1 · Cited by 233

EGF amplifies the replacement of parvalbumin-expressing striatal interneurons after ischemia

Teramoto, T., Qiu, J., Plumier, J.-C., & Moskowitz, M. A. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17170 · Cited by 226

Region-specific generation of cholinergic neurons from fetal human neural stem cells grafted in adult rat

Wu, P., Tarasenko, Y. I., Gu, Y., Huang, L.-Y. M., Coggeshall, R. E., & Yu, Y. (2002) · Nature Neuroscience · doi:10.1038/nn974 · Cited by 221

Dyskinesia after fetal cell transplantation for parkinsonism: A PET study

Ma, Y., Feigin, A., Dhawan, V., Fukuda, M., Shi, Q., Greene, P., Breeze, R., Fahn, S., Freed, C., & Eidelberg, D. (2002) · Annals of Neurology · doi:10.1002/ana.10359 · Cited by 219

Lineage-Restricted Neural Precursors Can Be Isolated from Both the Mouse Neural Tube and Cultured ES Cells

Mujtaba, T., Piper, D. R., Kalyani, A., Groves, A. K., Lucero, M. T., & Rao, M. S. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9418 · Cited by 203

VEGF is a chemoattractant for FGF-2–stimulated neural progenitors

Zhang, H., Vutskits, L., Pepper, M. S., & Kiss, J. Z. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200308040 · Cited by 200

Stem cell factor stimulates neurogenesis in vitro and in vivo

Jin, K., Mao, X. O., Sun, Y., Xie, L., & Greenberg, D. A. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215251 · Cited by 200

Embryonic Stem Cells Differentiated in Vitro as a Novel Source of Cells for Transplantation

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Chapter 13 Clinical observations after neural transplantation in Parkinson's disease

Lindvall, O., & Hagell, P. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)27014-3 · Cited by 180

Spinal Cord Neuronal Precursors Generate Multiple Neuronal Phenotypes in Culture

Kalyani, A. J., Piper, D., Mujtaba, T., Lucero, M. T., & Rao, M. S. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-19-07856.1998 · Cited by 179

Cell Survival and Clinical Outcome Following Intrastriatal Transplantation in Parkinson Disease

Hagell, P., & Brundin, P. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.8.741 · Cited by 174

Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors

Yan, J., Studer, L., & McKay, R. D. G. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00073.x · Cited by 171

Adenovirally Expressed Noggin and Brain-Derived Neurotrophic Factor Cooperate to Induce New Medium Spiny Neurons from Resident Progenitor Cells in the Adult Striatal Ventricular Zone

Chmielnicki, E., Benraiss, A., Economides, A. N., & Goldman, S. A. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1554-03.2004 · Cited by 171

Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson disease: a pilot study: Report of three cases

Mendez, I., Dagher, A., Hong, M., Gaudet, P., Weerasinghe, S., McAlister, V., King, D., Desrosiers, J., Darvesh, S., Acorn, T., et al. (2002) · Journal of Neurosurgery · doi:10.3171/jns.2002.96.3.0589 · Cited by 165

Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain

Englund, U., Björklund, A., & Wictorin, K. (2002) · Developmental Brain Research · doi:10.1016/s0165-3806(01)00330-3 · Cited by 163

Striatal neural grafting improves cortical metabolism in Huntington's disease patients

Gaura-Schmidt, V., Bachoud-Lévi, A.-C., Ribeiro, M.-J., Nguyen, J.-P., Frouin, V., Baudic, S., Brugières, P., Mangin, J.-F., Boissé, M.-F., Palfi, S., et al. (2003) · Brain · doi:10.1093/brain/awh003 · Cited by 152

A Clonal Line of Mesencephalic Progenitor Cells Converted to Dopamine Neurons by Hematopoietic Cytokines: A Source of Cells for Transplantation in Parkinson's Disease

Carvey, P. M., Ling, Z. D., Sortwell, C. E., Pitzer, M. R., McGuire, S. O., Storch, A., & Collier, T. J. (2001) · Experimental Neurology · doi:10.1006/exnr.2001.7735 · Cited by 144

Toward full restoration of synaptic and terminal function of the dopaminergic system in Parkinson's disease by stem cells

Ole Isacson, A., Björklund, L. M., & Schumacher, J. M. (2003) · Annals of Neurology · doi:10.1002/ana.10482 · Cited by 134

Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord

Roy, N. S., Nakano, T., Keyoung, H. M., Windrem, M. S., Rashbaum, W. K., Alonso, M. L., Kang, J., Peng, W., Carpenter, M. K., Lin, J. H.-C., et al. (2004) · Nature Biotechnology · doi:10.1038/nbt944 · Cited by 130

Deep Brain Stimulation for Parkinson’s Disease

Vitek, J. L. (2002) · Stereotactic and Functional Neurosurgery · doi:10.1159/000068959 · Cited by 128

Generation of Tyrosine Hydroxylase-Producing Neurons from Precursors of the Embryonic and Adult Forebrain

Daadi, M. M., & Weiss, S. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-11-04484.1999 · Cited by 123

Serial [18F]Fluorodeoxyglucose Positron Emission Tomography after Human Neuronal Implantation for Stroke

MELTZER, C. C., Kondziolka, D. S., Villemagne, V. L., Wechsler, L. R., Goldstein, S., Thulborn, K. R., Gebel, J., Elder, E. M., DeCesare, S., & Jacobs, A. (2001) · Neurosurgery · doi:10.1097/00006123-200109000-00011 · Cited by 122

Neurons derived in vitro from ES cells express homeoproteins characteristic of motoneurons and interneurons

Renoncourt, Y., Carroll, P., Filippi, P., Gorvel, V. A., & Alonso, S. (1998) · Mechanisms of Development · doi:10.1016/s0925-4773(98)00189-0 · Cited by 103

Positive Effect of Transplantation of hNT Neurons (NTera 2/D1 Cell-Line) in a Model of Familial Amyotrophic Lateral Sclerosis

Garbuzova-Davis, S. N., Willing, A. E., Milliken, M., Saporta, S., Žigová, T., Cahill, D. W., & Sanberg, P. R. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.7860 · Cited by 100

Chapter 11 Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement

Winkler, C., Kirik, D., Björklund, A., & Dunnett, S. B. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)27012-x · Cited by 98

Embryonic mesencephalic grafts increase levodopa‐induced forelimb hyperkinesia in parkinsonian rats

Steece‐Collier, K., Collier, T. J., Danielson, P. D., Kurlan, R., Yurek, D. M., & Sladek, J. R. (2003) · Movement Disorders · doi:10.1002/mds.10588 · Cited by 94

Late-Stage Immature Neocortical Neurons Reconstruct Interhemispheric Connections and Form Synaptic Contacts with Increased Efficiency in Adult Mouse Cortex Undergoing Targeted Neurodegeneration

Fricker‐Gates, R. A., Shin, J. J., Tai, C. C., Catapano, L. A., & Macklis, J. D. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-10-04045.2002 · Cited by 93

Profound astrogenesis in the striatum of adult mice following nigrostriatal dopaminergic lesion by repeated MPTP administration

Mao, L., Lau, Y., Petroske, E., & Wang, J. Q. (2001) · Developmental Brain Research · doi:10.1016/s0165-3806(01)00260-7 · Cited by 90

Long-term molecular and cellular stability of human neural stem cell lines

Villa, A., Navarro‐Galve, B., Bueno, C., Franco, S., Blasco, M. A., & Martı́nez-Serrano, A. (2004) · Experimental Cell Research · doi:10.1016/j.yexcr.2003.11.025 · Cited by 84

Chapter 16 The integration and function of striatal grafts

Dunnett, S. B., Nathwani, F., & Björklund, A. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)27017-9 · Cited by 71

Anterograde delivery of brain‐derived neurotrophic factor to striatum via nigral transduction of recombinant adeno‐associated virus increases neuronal death but promotes neurogenic response following stroke

Gustafsson, E., Andsberg, G., Darsalia, V., Mohapel, P., Mandel, R. J., Kirik, D., Lindvall, O., & Kokaia, Z. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02713.x · Cited by 60

Ectopic Expression of Cell Cycle Markers in Models of Induced Programmed Cell Death in Dopamine Neurons of the Rat Substantia Nigra Pars Compacta

El‐Khodor, B. F., Oo, T. F., Kholodilov, N. G., & Burke, R. E. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.8047 · Cited by 57

Transplantation of Motoneuron-Enriched Neural Cells Derived from Mouse Embryonic Stem Cells Improves Motor Function of Hemiplegic Mice

Chiba, S., Iwasaki, Y., Sekino, H., & Suzuki, N. (2003) · Cell Transplantation · doi:10.3727/000000003108747019 · Cited by 56

Reconstructive neurosurgery for Parkinson’s disease: a systematic review and preliminary meta-analysis

Polgar, S., Morris, M. E., Reilly, S., Bilney, B., & Sanberg, P. R. (2003) · Brain Research Bulletin · doi:10.1016/s0361-9230(03)00017-0 · Cited by 48

Caspase‐mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus

Ekdahl, C. T., Mohapel, P., Weber, E., Bahr, B. A., Blomgren, K., & Lindvall, O. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02202.x · Cited by 39

Motoneuron differentiation of immortalized human spinal cord cell lines

Li, R., Thode, S., Zhou, J., Richard, N., Pardinas, J. R., Rao, M. S., & Sah, D. W. Y. (2000) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(20000201)59:3<342::aid-jnr7>3.0.co;2-z · Cited by 36

hNT neurons delay onset of motor deficits in a model of amyotrophic lateral sclerosis

Willing, A. E., Garbuzova-Davis, S. N., Saporta, S., Milliken, M., Cahill, D. W., & Sanberg, P. R. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00625-6 · Cited by 33

Stem Cells The Promises and Pitfalls

Nowakowski, R. S. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00379-7 · Cited by 30

Intraspinal implantation of hNT neurons into SOD1 mice with apparent motor deficit

Garbuzova-Davis, S. N., Willing, A. E., Milliken, M., et al. (2001) · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders · doi:10.1080/14660820152882179 · Cited by 30

Chapter 7 Reconstruction of cortical circuitry

Gates, M. A., Fricker‐Gates, R. A., & Macklis, J. D. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)27008-8 · Cited by 27

Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic

Zhang, Z. G., & Chopp, M. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70061-4 · Cited by 596

Identification of intrinsic determinants of midbrain dopamine neurons

Andersson, E., Tryggvason, U., Deng, Q., Friling, S., Alekseenko, Z., Robert, B., Perlmann, T., & Ericson, J. (2006) · Cell · doi:10.1016/j.cell.2005.10.037 · Cited by 587

Magnetically actuated microrobots as a platform for stem cell transplantation

Jeon, S., Kim, S., Ha, S., Lee, S., Kim, E., Kim, S. Y., Park, S. H., Jeon, J. H., Kim, S. W., Moon, C., et al. (2019) · Science Robotics · doi:10.1126/scirobotics.aav4317 · Cited by 412

Retinal Prosthesis

Weiland, J. D., Liu, W., & Humayun, M. S. (2005) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.7.060804.100435 · Cited by 371

Neurogenesis, angiogenesis, and MRI indices of functional recovery from stroke

Chopp, M., Zhang, Z. G., & Jiang, Q. (2007) · Stroke · doi:10.1161/01.str.0000250235.80253.e9 · Cited by 203