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The Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety Disorders
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Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120
Biological insights from 108 schizophrenia-associated genetic loci
Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014) · Nature · doi:10.1038/nature13595 · Cited by 7,577
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bulik-Sullivan, B. K., Loh, P.-R., Finucane, H. K., Ripke, S., Yang, J., Patterson, N., Daly, M. J., Price, A. L., & Neale, B. M. (2015) · Nature Genetics · doi:10.1038/ng.3211 · Cited by 5,559
Genetic Epidemiology of Major Depression: Review and Meta-Analysis
Sullivan, P. F., Neale, M. C., & Kendler, K. S. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.10.1552 · Cited by 3,431
Predictors of posttraumatic stress disorder and symptoms in adults: a meta-analysis
Ozer, E. J., Best, S. R., Lipsey, T. L., & Weiss, D. S. (2003) · Psychological Bulletin · doi:10.1037/0033-2909.129.1.52 · Cited by 3,322 · cited 2×
“In addition other environmental exposures, including childhood maltreatment, poverty, and low social support, have been shown to increase the risk of PTSD among trauma-exposed individuals (DiGangi et al, 2013b; Ozer et al, 2003).”
BackgroundFerrari, A. J., Charlson, F. J., Norman, R. E., Patten, S. B., Freedman, G., Murray, C. J. L., Vos, T., & Whiteford, H. A. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001547 · Cited by 3,115
(2013) · The Lancet · doi:10.1016/s0140-6736(12)62129-1 · Cited by 3,010
Hammen, C. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143938 · Cited by 2,979 · cited 2×
“A variety of stressful life events have been shown to increase the risk for depression (Hammen, 2005; Kessler, 1997) including poverty (Brooks-Gunn and Duncan, 1997; McLeod and Shanahan, 1996), negative family relationships and parental divorce (Gilman et al, 2003; Repetti et al, 2002), and childhood maltreatment (Cha…”
BackgroundRisky families: Family social environments and the mental and physical health of offspring
Repetti, R. L., Taylor, S. E., & Seeman, T. E. (2002) · Psychological Bulletin · doi:10.1037/0033-2909.128.2.330 · Cited by 2,884
Research works printed but not linked: 217
- Abelson JL, Khan S, Liberzon I, Young EA (2007). HPA axis activity in patients with panic disorder: review and synthesis of four studies. Depress Anxiety 24: 66–76. · DOI · Paper page
- Afari N, Noonan C, Goldberg J, Roy-Byrne P, Schur E, Golnari G et al (2010). Depression and obesity: do shared genes explain the relationship? Depress Anxiety 27: 799–806. · DOI
- Almli LM, Mercer KB, Kerley K, Feng H, Bradley B, Conneely KN et al (2013). ADCYAP1R1 genotype associates with post-traumatic stress symptoms in highly traumatized African-American females. Am J Med Genet B Neuropsychiatr Genet 162B: 262–272. · DOI
- Almli LM, Srivastava A, Fani N, Kerley K, Mercer KB, Feng H et al (2014). Follow-up and extension of a prior genome-wide association study of posttraumatic stress disorder: gene x environment associations and structural magnetic resonance imaging in a highly traumatized African-American civilian population. Biol Psychiatry 76: e3–e4. · DOI
- Amstadter AB, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG et al (2009). Variant in RGS2 moderates posttraumatic stress symptoms following potentially traumatic event exposure. J Anxiety Disord 23: 369–373. · DOI
- Amstadter AB, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG et al (2010). NPY moderates the relation between hurricane exposure and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults. Depress Anxiety 27: 270–275. · DOI
- Amstadter AB, Sumner JA, Acierno R, Ruggiero KJ, Koenen KC, Kilpatrick DG et al (2013). Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults. Mol Psychiatry 18: 1148–1149. · DOI
- Andero R, Brothers SP, Jovanovic T, Chen YT, Salah-Uddin H, Cameron M et al (2013). Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Sci Transl Med 5: 188ra173. · DOI
- Andero R, Ressler KJ (2012). Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes Brain Behav 11: 503–512. · DOI · Paper page
- Anglin RE, Mazurek MF, Tarnopolsky MA, Rosebush PI (2012). The mitochondrial genome and psychiatric illness. Am J Med Genet B Neuropsychiatr Genet 159B: 749–759. · DOI
- Ashley-Koch AE, Garrett ME, Gibson J, Liu Y, Dennis MF, Kimbrel NA et al (2015). Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans. J Affect Disord 184: 225–234. · DOI
- Bastiaansen JA, Servaas MN, Marsman JB, Ormel J, Nolte IM, Riese H et al (2014). Filling the gap: relationship between the serotonin-transporter-linked polymorphic region and amygdala activation. Psychol Sci 25: 2058–2066. · DOI
- Battaglia M, Ogliari A (2005). Anxiety and panic: from human studies to animal research and back. Neurosci Biobehav Rev 29: 169–179. · DOI
- Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB et al (2008). Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA 299: 1291–1305. · DOI · Paper page
- Blackwood DH, Fordyce A, Walker MT, St Clair DM, Porteous DJ, Muir WJ (2001). Schizophrenia and affective disorders—cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet 69: 428–433. · DOI · Paper page
- Bland RC, Newman SC, Orn H (1986). Recurrent and nonrecurrent depression: a family study. Arch Gen Psychiatry 43: 1085–1089. · DOI
- Blaya C, Salum GA, Moorjani P, Seganfredo AC, Heldt E, Leistner-Segal S et al (2010). Panic disorder and serotonergic genes (SLC6A4, HTR1A and HTR2A): association and interaction with childhood trauma and parenting. Neurosci Lett 485: 11–15. · DOI
- Boyle L, Kaufmann WE (2010). The behavioral phenotype of FMR1 mutations. Am J Med Genet C Semin Med Genet 154C: 469–476. · DOI
- Bradley RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W et al (2008). Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry 65: 190–200. · DOI · Paper page
- Brand H, Pillalamarri V, Collins RL, Eggert S, O'Dushlaine C, Braaten EB et al (2014). Cryptic and complex chromosomal aberrations in early-onset neuropsychiatric disorders. Am J Hum Genet 95: 454–461. · DOI
- Casey BJ, Pattwell SS, Glatt CE, Lee FS (2013). Treating the developing brain: implications from human imaging and mouse genetics. Ann Rev Med 64: 427–439. · DOI
- Champoux M, Bennett A, Shannon C, Higley JD, Lesch KP, Suomi SJ (2002). Serotonin transporter gene polymorphism, differential early rearing, and behavior in rhesus monkey neonates. Mol Psychiatry 7: 1058–1063. · DOI · Paper page
- Chang SC, Glymour MM, Walter S, Liang L, Koenen KC, Tchetgen EJ et al (2014). Genome-wide polygenic scoring for a 14-year long-term average depression phenotype. Brain Behav 4: 298–311. · DOI
- Chang SC, Xie P, Anton RF, De Vivo I, Farrer LA, Kranzler HR et al (2012). No association between ADCYAP1R1 and post-traumatic stress disorder in two independent samples. Mol Psychiatry 17: 239–241. · DOI
- Chantarujikapong SI, Scherrer JF, Xian H, Eisen SA, Lyons MJ, Goldberg J et al (2001). A twin study of generalized anxiety disorder symptoms, panic disorder symptoms and post-traumatic stress disorder in men. Psychiatry Res 103: 133–145. · DOI · Paper page
- Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF (2004). Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 82: 217–225. · DOI · Paper page
- Chatterjee N, Wheeler B, Sampson J, Hartge P, Chanock SJ, Park JH (2013). Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies. Nat Genet 45: 400–405, 405e401-403. · DOI · Paper page
- Choe AY, Kim B, Lee KS, Lee JE, Lee JY, Choi TK et al (2013). Serotonergic genes (5-HTT and HTR1A) and separation life events: gene-by-environment interaction for panic disorder. Neuropsychobiology 67: 192–200. · DOI
- Choi KH, Higgs BW, Wendland JR, Song J, McMahon FJ, Webster MJ (2011). Gene expression and genetic variation data implicate PCLO in bipolar disorder. Biol Psychiatry 69: 353–359. · DOI
- Cianfaglione R, Clarke A, Kerr M, Hastings RP, Oliver C, Moss J et al (2015). A national survey of Rett syndrome: behavioural characteristics. J Neurodev Disord 7: 11. · DOI
- Clarke H, Flint J, Attwood AS, Munafo MR (2010). Association of the 5- HTTLPR genotype and unipolar depression: a meta-analysis. Psychol Med 40: 1767–1778. · DOI · Paper page
- Cole J, Ball HA, Martin NC, Scourfield J, McGuffin P (2009). Genetic overlap between measures of hyperactivity/inattention and mood in children and adolescents. J Am Acad Child Adolesc Psychiatry 48: 1094–1101. · DOI · Paper page
- Cornelis MC, Nugent NR, Amstadter AB, Koenen KC (2010). Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies. Curr Psychiatry Rep 12: 313–326. · DOI · Paper page
- Coryell MW, Ziemann AE, Westmoreland PJ, Haenfler JM, Kurjakovic Z, Zha XM et al (2007). Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit. Biol Psychiatry 62: 1140–1148. · DOI
- Costello EJ, Egger HL, Angold A (2005). The developmental epidemiology of anxiety disorders: phenomenology, prevalence, and comorbidity. Child Adolesc Psychiatr Clin N Am 14: 631–648, vii. · DOI · Paper page
- Cukier HN, Dueker ND, Slifer SH, Lee JM, Whitehead PL, Lalanne E et al (2014). Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders. Mol Autism 5: 1. · DOI · Paper page
- Dadu RT, Ballantyne CM (2014). Lipid lowering with PCSK9 inhibitors. Nat Rev Cardiol 11: 563–575. · DOI · Paper page
- de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T et al (2012). Meta-analysis of genome-wide association studies for personality. Mol Psychiatry 17: 337–349. · DOI · Paper page
- Demirkan A, Penninx BW, Hek K, Wray NR, Amin N, Aulchenko YS et al (2011). Genetic risk profiles for depression and anxiety in adult and elderly cohorts. Mol Psychiatry 16: 773–783. · DOI · Paper page
- Digangi J, Guffanti G, McLaughlin KA, Koenen KC (2013a). Considering trauma exposure in the context of genetics studies of posttraumatic stress disorder: a systematic review. Biol Mood Anxiety Disord 3: 2. · DOI
- DiGangi JA, Gomez D, Mendoza L, Jason LA, Keys CB, Koenen KC (2013b). Pretrauma risk factors for posttraumatic stress disorder: a systematic review of the literature. Clin Psychol Rev 33: 728–744. · DOI · Paper page
- Domschke K, Dannlowski U (2010). Imaging genetics of anxiety disorders. NeuroImage 53: 822–831. · DOI
- Donner J, Sipila T, Ripatti S, Kananen L, Chen X, Kendler KS et al (2012). Support for involvement of glutamate decarboxylase 1 and neuropeptide Y in anxiety susceptibility. Am J Med Genet B Neuropsychiatr Genet 159B: 316–327. · DOI
- Duncan LE, Holmans PA, Lee PH, O'Dushlaine CT, Kirby AW, Smoller JW et al (2014a). Pathway analyses implicate glial cells in schizophrenia. PLoS One 9: e89441. · DOI
- Duncan LE, Pollastri AR, Smoller JW (2014b). Mind the gap: why many geneticists and psychological scientists have discrepant views about gene-environment interaction (GxE) research. Am Psychol 69: 249–268. · DOI
- Dunn EC, Uddin M, Subramanian SV, Smoller JW, Galea S, Koenen KC (2011). Research review: gene-environment interaction research in youth depression—a systematic review with recommendations for future research. J Child Psychol Psychiatry 52: 1223–1238. · DOI
- Ebert DH, Finn CT, Stoler JM, Smoller JW (2010) Genetics and psychiatry. In: Stern TA, Fricchione GL, Cassem NH, Jellinek MS, Rosenbaum JF (eds). Massacusetts General Hospital Handbook of General Hospital Psychiatry, 6th edn. Elsevier, Inc.: Philadelphia, PA, pp 409–423. · DOI
- Edwards AC, Kendler KS (2012). A twin study of depression and nicotine dependence: shared liability or causal relationship? J Affect Disord 142: 90–97. · DOI
- Enoch MA, White KV, Waheed J, Goldman D (2008). Neurophysiological and genetic distinctions between pure and comorbid anxiety disorders. Depress Anxiety 25: 383–392. · DOI
- Erhardt A, Akula N, Schumacher J, Czamara D, Karbalai N, Muller-Myhsok B et al (2012). Replication and meta-analysis of TMEM132D gene variants in panic disorder. Transl Psychiatry 2: e156. · DOI
- Erhardt A, Czibere L, Roeske D, Lucae S, Unschuld PG, Ripke S et al (2011). TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies. Mol Psychiatry 16: 647–663. · DOI · Paper page
- Fani N, Gutman D, Tone EB, Almli L, Mercer KB, Davis J et al (2013). FKBP5 and attention bias for threat: associations with hippocampal function and shape. JAMA Psychiatry 70: 392–400. · DOI
- Faraone SV, Biederman J (1997). Do attention deficit hyperactivity disorder and major depression share familial risk factors? J Nerv Ment Dis 185: 533–541. · DOI · Paper page
- Fergusson DM, Horwood LJ, Miller AL, Kennedy MA (2011). Life stress, 5-HTTLPR and mental disorder: findings from a 30-year longitudinal study. Br J Psychiatry 198: 129–135. · DOI
- Flaquer A, Baumbach C, Ladwig KH, Kriebel J, Waldenberger M, Grallert H et al (2015). Mitochondrial genetic variants identified to be associated with posttraumatic stress disorder. Transl Psychiatry 5: e524. · DOI
- Fung WL, McEvilly R, Fong J, Silversides C, Chow E, Bassett A (2010). Elevated prevalence of generalized anxiety disorder in adults with 22q11.2 deletion syndrome. Am J Psychiatry 167: 998. · DOI
- Gao J, Pan Z, Jiao Z, Li F, Zhao G, Wei Q et al (2012). TPH2 gene polymorphisms and major depression—a meta-analysis. PLoS One 7: e36721. · DOI
- Gatt JM, Burton KL, Williams LM, Schofield PR (2015). Specific and common genes implicated across major mental disorders: a review of meta-analysis studies. J Psychiatr Res 60: 1–13. · DOI · Paper page
- Ge T, Nichols TE, Lee PH, Holmes AJ, Roffman JL, Buckner RL et al (2015). Massively expedited genome-wide heritability analysis (MEGHA). Proc Natl Acad Sci USA 112: 2479–2484. · DOI
- Gibb BE, Chelminski I, Zimmerman M (2007). Childhood emotional, physical, and sexual abuse, and diagnoses of depressive and anxiety disorders in adult psychiatric outpatients. Depress Anxiety 24: 256–263. · DOI · Paper page
- Gilman SE, Kawachi I, Fitzmaurice GM, Buka SL (2003). Family disruption in childhood and risk of adult depression. Am J Psychiatry 160: 939–946. · DOI · Paper page
- Gilman SE, Ni MY, Dunn EC, Breslau J, McLaughlin KA, Smoller JW et al (2015). Contributions of the social environment to first-onset and recurrent mania. Mol Psychiatry 20: 329–336. · DOI
- Glessner JT, Wang K, Sleiman PM, Zhang H, Kim CE, Flory JH et al (2010). Duplication of the SLIT3 locus on 5q35.1 predisposes to major depressive disorder. PLoS One 5: e15463. · DOI
- Green EK, Grozeva D, Forty L, Gordon-Smith K, Russell E, Farmer A et al (2013). Association at SYNE1 in both bipolar disorder and recurrent major depression. Mol Psychiatry 18: 614–617. · DOI
- Green EK, Grozeva D, Jones I, Jones L, Kirov G, Caesar S et al (2010). The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry 15: 1016–1022. · DOI · Paper page
- Green EK, Rees E, Walters JT, Smith KG, Forty L, Grozeva D et al (2015). Copy number variation in bipolar disorder. Mol Psychiatry (doi:10.1038/mp.2014.174; e-pub ahead of print). · DOI · Paper page
- Gressier F, Calati R, Balestri M, Marsano A, Alberti S, Antypa N et al (2013). The 5-HTTLPR polymorphism and posttraumatic stress disorder: a meta-analysis. J Trauma Stress 26: 645–653. · DOI
- Guffanti G, Ashley-Koch AE, Roberts AL, Garrett ME, Solovieff N, Ratanatharathorn A et al (2014). No association between RORA polymorphisms and PTSD in two independent samples. Mol Psychiatry 19: 1056–1057. · DOI
- Guffanti G, Galea S, Yan L, Roberts AL, Solovieff N, Aiello AE et al (2013). Genome-wide association study implicates a novel RNA gene, the lincRNA AC068718.1, as a risk factor for post-traumatic stress disorder in women. Psychoneuroendocrinology 38: 3029–3038. · DOI · Paper page
- Haaker J, Lonsdorf TB, Raczka KA, Mechias ML, Gartmann N, Kalisch R (2014). Higher anxiety and larger amygdala volumes in carriers of a TMEM132D risk variant for panic disorder. Transl Psychiatry 4: e357. · DOI
- Heim C, Bradley B, Mletzko TC, Deveau TC, Musselman DL, Nemeroff CB et al (2009). Effect of childhood trauma on adult depression and neuroendocrine function: sex-specific moderation by CRH receptor 1 gene. Front Behav Neurosci 3: 41. · DOI · Paper page
- Hek K, Mulder CL, Luijendijk HJ, van Duijn CM, Hofman A, Uitterlinden AG et al (2010). The PCLO gene and depressive disorders: replication in a population-based study. Hum Mol Genet 19: 731–734. · DOI
- Hettema JM, An SS, Neale MC, Bukszar J, van den Oord EJ, Kendler KS et al (2006a). Association between glutamic acid decarboxylase genes and anxiety disorders, major depression, and neuroticism. Mol Psychiatry 11: 752–762. · DOI · Paper page
- Hettema JM, Chen X, Sun C, Brown TA (2015). Direct, indirect and pleiotropic effects of candidate genes on internalizing disorder psychopathology. Psychol Med 1–10. · DOI
- Hettema JM, Neale MC, Kendler KS (2001). A review and meta-analysis of the genetic epidemiology of anxiety disorders. Am J Psychiatry 158: 1568–1578. · DOI · Paper page
- Hettema JM, Neale MC, Myers JM, Prescott CA, Kendler KS (2006b). A population-based twin study of the relationship between neuroticism and internalizing disorders. Am J Psychiatry 163: 857–864. · DOI · Paper page
- Hettema JM, Prescott CA, Myers JM, Neale MC, Kendler KS (2005). The structure of genetic and environmental risk factors for anxiety disorders in men and women. Arch Gen Psychiatry 62: 182–189. · DOI · Paper page
- Hettema JM, Webb BT, Guo AY, Zhao Z, Maher BS, Chen X et al (2011). Prioritization and association analysis of murine-derived candidate genes in anxiety-spectrum disorders. Biol Psychiatry 70: 888–896. · DOI
- Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivieres S, Jahanshad N et al (2015). Common genetic variants influence human subcortical brain structures. Nature 520: 224–229. · DOI · Paper page
- Hohoff C, Weber H, Richter J, Domschke K, Zwanzger PM, Ohrmann P et al (2015). RGS2 genetic variation: association analysis with panic disorder and dimensional as well as intermediate phenotypes of anxiety. Am J Med Genet B Neuropsychiatr Genet 168: 211–222. · DOI
- Holmes A, Lit Q, Murphy DL, Gold E, Crawley JN (2003). Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background. Genes Brain Behav 2: 365–380. · DOI · Paper page
- Howe AS, Buttenschon HN, Bani-Fatemi A, Maron E, Otowa T, Erhardt A et al (2015). Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways. Mol Psychiatry (doi:10.1038/mp.2015.138; e-pub ahead of print). · DOI
- Insel TR (2014). Brain somatic mutations: the dark matter of psychiatric genetics? Mol Psychiatry 19: 156–158. · DOI
- Insel TR, Cuthbert BN (2009). Endophenotypes: bridging genomic complexity and disorder heterogeneity. Biol Psychiatry 66: 988–989. · DOI · Paper page
- Ishitobi Y, Nakayama S, Yamaguchi K, Kanehisa M, Higuma H, Maruyama Y et al (2012). Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population. Am J Med Genet B Neuropsychiatr Genet 159B: 429–436. · DOI
- Jang KL, Taylor S, Stein MB, Yamagata S (2007). Trauma exposure and stress response: exploration of mechanisms of cause and effect. Twin Res Hum Genet 10: 564–572. · DOI
- Kao CF, Jia P, Zhao Z, Kuo PH (2012). Enriched pathways for major depressive disorder identified from a genome-wide association study. Int J Neuropsychopharmacol 15: 1401–1411. · DOI
- Karg K, Burmeister M, Shedden K, Sen S (2011). The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. Arch Gen Psychiatry 68: 444–454. · DOI · Paper page
- Kathiresan S (2015). Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP. J Am Coll Cardiol 65: 1562–1566. · DOI
- Kato T (2015). Whole genome/exome sequencing in mood and psychotic disorders. Psychiatry Clin Neurosci 69: 65–76. · DOI
- Kawamura Y, Otowa T, Koike A, Sugaya N, Yoshida E, Yasuda S et al (2011). A genome-wide CNV association study on panic disorder in a Japanese population. J Hum Genet 56: 852–856. · DOI
- Kendler KS, Aggen SH, Neale MC (2013). Evidence for multiple genetic factors underlying DSM-IV criteria for major depression. JAMA Psychiatry 70: 599–607. · DOI
- Kendler KS, Gardner CO, Gatz M, Pedersen NL (2007). The sources of co-morbidity between major depression and generalized anxiety disorder in a Swedish national twin sample. Psychol Med 37: 453–462. · DOI · Paper page
- Kendler KS, Gardner CO, Prescott CA (1999a). Clinical characteristics of major depression that predict risk of depression in relatives. Arch Gen Psychiatry 56: 322–327; erratum 2000;2057:2094-2095. · DOI
- Kendler KS, Gatz M, Gardner CO, Pedersen NL (2005). Age at onset and familial risk for major depression in a Swedish national twin sample. Psychol Med 35: 1573–1579. · DOI
- Kendler KS, Heath AC, Neale MC, Kessler RC, Eaves LJ (1993a). Alcoholism and major depression in women. A twin study of the causes of comorbidity. Arch Gen Psychiatry 50: 690–698. · DOI · Paper page
- Kendler KS, Karkowski LM, Prescott CA (1999b). Fears and phobias: reliability and heritability. Psychol Med 29: 539–553. · DOI · Paper page
- Kendler KS, Myers J (2010). The genetic and environmental relationship between major depression and the five-factor model of personality. Psychol Med 40: 801–806. · DOI · Paper page
- Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1993b). A longitudinal twin study of personality and major depression in women. Arch Gen Psychiatry 50: 853–862. · DOI · Paper page
- Keyes KM, Smith GD, Koenen KC, Galea S (2015). The mathematical limits of genetic prediction for complex chronic disease. J Epidemiol Commun Health 69: 574–579. · DOI
- Kishi T, Yoshimura R, Fukuo Y, Okochi T, Matsunaga S, Umene-Nakano W et al (2013). The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder. Eur Arch Psychiatry Clin Neurosci 263: 105–118. · DOI
- Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM et al (2013). Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci 16: 33–41. · DOI · Paper page
- Koenen KC, Amstadter AB, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG et al (2009). RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults. Depress Anxiety 26: 309–315. · DOI
- Koenen KC, Fu QJ, Ertel K, Lyons MJ, Eisen SA, True WR et al (2008). Common genetic liability to major depression and posttraumatic stress disorder in men. J Affect Disord 105: 109–115. · DOI
- Koenen KC, Lyons MJ, Goldberg J, Simpson J, Williams WM, Toomey R et al (2003). A high risk twin study of combat-related PTSD comorbidity. Twin Res 6: 218–226. · DOI
- Kuehner C, Huffziger S, Witt SH, Rietschel M (2011). PCLO rs2522833 impacts HPA system activity in healthy young adults. Transl Psychiatry 1: e10. · DOI
- Laucht M, Treutlein J, Blomeyer D, Buchmann AF, Schmid B, Becker K et al (2009). Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults. Int J Neuropsychopharmacol 12: 737–747. · DOI
- Laucht M, Treutlein J, Blomeyer D, Buchmann AF, Schmidt MH, Esser G et al (2013). Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults: findings from a longitudinal study. Eur Neuropsychopharmacol 23: 358–367. · DOI
- Lee PH, Perlis RH, Jung JY, Byrne EM, Rueckert E, Siburian R et al (2012). Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. Transl Psychiatry 2: e184. · DOI
- Leen-Feldner EW, Feldner MT, Knapp A, Bunaciu L, Blumenthal H, Amstadter AB (2013). Offspring psychological and biological correlates of parental posttraumatic stress: review of the literature and research agenda. Clin Psychol Rev 33: 1106–1133. · DOI · Paper page
- Leyfer O, Woodruff-Borden J, Mervis CB (2009). Anxiety disorders in children with williams syndrome, their mothers, and their siblings: implications for the etiology of anxiety disorders. J Neurodev Disord 1: 4–14. · DOI
- Leygraf A, Hohoff C, Freitag C, Willis-Owen SA, Krakowitzky P, Fritze J et al (2006). Rgs 2 gene polymorphisms as modulators of anxiety in humans? J Neural Transm 113: 1921–1925. · DOI
- Liberzon I, King AP, Ressler KJ, Almli LM, Zhang P, Ma ST et al (2014). Interaction of the ADRB2 gene polymorphism with childhood trauma in predicting adult symptoms of posttraumatic stress disorder. JAMA Psychiatry 71: 1174–1182. · DOI
- Ligthart L, Nyholt DR, Penninx BW, Boomsma DI (2010). The shared genetics of migraine and anxious depression. Headache 50: 1549–1560. · DOI
- Logue MW, Amstadter AB, Baker DG, Duncan L, Koenen KC, Liberzon I et al (2015). The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: posttraumatic stress disorder enters the age of large-scale genomic collaboration. Neuropsychopharmacology 40: 2287–2297. · DOI · Paper page
- Logue MW, Baldwin C, Guffanti G, Melista E, Wolf EJ, Reardon AF et al (2013). A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. Mol Psychiatry 18: 937–942. · DOI · Paper page
- Loken EK, Hettema JM, Aggen SH, Kendler KS (2014). The structure of genetic and environmental risk factors for fears and phobias. Psychol Med 44: 2375–2384. · DOI
- López-León S, Janssens AC, González-Zuloeta Ladd AM, Del-Favero J, Claes SJ, Oostra BA et al (2007). Meta-analyses of genetic studies on major depressive disorder. Mol Psychiatry 13: 772–785. · DOI · Paper page
- Lubke GH, Hottenga JJ, Walters R, Laurin C, de Geus EJ, Willemsen G et al (2012). Estimating the genetic variance of major depressive disorder due to all single nucleotide polymorphisms. Biol Psychiatry 72: 707–709. · DOI
- Luciano M, Huffman JE, Arias-Vasquez A, Vinkhuyzen AA, Middeldorp CM, Giegling I et al (2012). Genome-wide association uncovers shared genetic effects among personality traits and mood states. Am J Med Genet B Neuropsychiatr Genet 159B: 684–695. · DOI
- Lyons M, Eisen S, Goldberg J, True W, Lin N, Meyer J et al (1998). A registry-based twin study of depression in men. Arch Gen Psychiatry 55: 468–472. · DOI · Paper page
- Mahon PB, Zandi PP, Potash JB, Nestadt G, Wand GS (2013). Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults. Psychopharmacology (Berl) 227: 231–241. · DOI
- Malhotra D, Sebat J (2012). CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell 148: 1223–1241. · DOI · Paper page
- Mandelli L, Serretti A (2013). Gene environment interaction studies in depression and suicidal behavior: an update. Neurosci Biobehav Rev 37: 2375–2397. · DOI · Paper page
- Manji H, Kato T, Di Prospero NA, Ness S, Beal MF, Krams M et al (2012). Impaired mitochondrial function in psychiatric disorders. Nat Rev Neurosci 13: 293–307. · DOI · Paper page
- Manoli I, Alesci S, Blackman MR, Su YA, Rennert OM, Chrousos GP (2007). Mitochondria as key components of the stress response. Trends Endocrinol Metab 18: 190–198. · DOI · Paper page
- Matheson SL, Shepherd AM, Pinchbeck RM, Laurens KR, Carr VJ (2013). Childhood adversity in schizophrenia: a systematic meta-analysis. Psychol Med 43: 225–238. · DOI · Paper page
- McGrath LM, Weill S, Robinson EB, Macrae R, Smoller JW (2012). Bringing a developmental perspective to anxiety genetics. Dev Psychopathol 24: 1179–1193. · DOI
- McGuffin P, Katz R, Watkins S, Rutherford J (1996). A hospital-based twin register of the heritability of DSM-IV unipolar depression. Arch Gen Psychiatry 53: 129–136. · DOI · Paper page
- McLeod JD, Shanahan MJ (1996). Trajectories of poverty and children's mental health. J Health Social Behav 37: 207–220. · DOI · Paper page
- Micco JA, Henin A, Mick E, Kim S, Hopkins CA, Biederman J et al (2009). Anxiety and depressive disorders in offspring at high risk for anxiety: a meta-analysis. J Anxiety Disord 23: 1158–1164. · DOI · Paper page
- Michelini G, Eley TC, Gregory AM, McAdams TA (2015). Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence. J Child Psychol Psychiatry 56: 423–431. · DOI
- Middeldorp CM, de Moor MH, McGrath LM, Gordon SD, Blackwood DH, Costa PT et al (2011). The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data. Transl Psychiatry 1: e50. · DOI
- Miller MW, Wolf EJ, Logue MW, Baldwin CT (2013). The retinoid-related orphan receptor alpha (RORA) gene and fear-related psychopathology. J Affect Disord 151: 702–708. · DOI
- Minelli A, Scassellati C, Cloninger CR, Tessari E, Bortolomasi M, Bonvicini C et al (2012). PCLO gene: its role in vulnerability to major depressive disorder. J Affect Disord 139: 250–255. · DOI
- Mouri K, Hishimoto A, Fukutake M, Nishiguchi N, Shirikawa O, Maeda K (2009). Association study of RGS2 gene polymorphisms with panic disorder in Japanese. Kobe J Med Sci 55: e116–e121.
- Moutsianas L, Agarwala V, Fuchsberger C, Flannick J, Rivas MA, Gaulton KJ et al (2015). The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease. PLoS Genet 11: e1005165. · DOI
- Munafo MR, Durrant C, Lewis G, Flint J (2009). Gene X environment interactions at the serotonin transporter locus. Biol Psychiatry 65: 211–219. · DOI · Paper page
- Musliner KL, Seifuddin F, Judy JA, Pirooznia M, Goes FS, Zandi PP (2014). Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis. Psychol Med 45: 1709–1720. · DOI
- Nievergelt CM, Maihofer AX, Mustapic M, Yurgil KA, Schork NJ, Miller MW et al (2015). Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: a genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. Psychoneuroendocrinology 51: 459–471. · DOI · Paper page
- Nivard MG, Mbarek H, Hottenga JJ, Smit JH, Jansen R, Penninx BW et al (2014). Further confirmation of the association between anxiety and CTNND2: replication in humans. Genes Brain Behav 13: 195–201. · DOI
- Nurnberger JI Jr, Koller DL, Jung J, Edenberg HJ, Foroud T, Guella I et al (2014). Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry 71: 657–664. · DOI · Paper page
- O'Dushlaine C, Ripke S, Ruderfer DM, Hamilton SP, Fava M, Iosifescu DV et al (2014). Rare copy number variation in treatment-resistant major depressive disorder. Biol Psychiatry 76: 536–541. · DOI
- Otowa T, Shimada T, Kawamura Y, Sugaya N, Yoshida E, Inoue K et al (2011). Association of RGS2 variants with panic disorder in a Japanese population. Am J Med Genet B Neuropsychiatr Genet 156B: 430–434. · DOI
- Otowa T, Tanii H, Sugaya N, Yoshida E, Inoue K, Yasuda S et al (2010). Replication of a genome-wide association study of panic disorder in a Japanese population. J Hum Genet 55: 91–96. · DOI
- Otowa T, Yoshida E, Sugaya N, Yasuda S, Nishimura Y, Inoue K et al (2009). Genome-wide association study of panic disorder in the Japanese population. J Hum Genet 54: 122–126. · DOI
- Pedroso I, Lourdusamy A, Rietschel M, Nothen MM, Cichon S, McGuffin P et al (2012). Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes. Biol Psychiatry 72: 311–317. · DOI · Paper page
- Perlis RH, Ruderfer D, Hamilton SP, Ernst C (2012). Copy number variation in subjects with major depressive disorder who attempted suicide. PLoS One 7: e46315. · DOI
- Perlis RH, Smoller JW, Mysore J, Sun M, Gillis T, Purcell S et al (2010). Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder. Am J Psychiatry 167: 574–579. · DOI
- Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW et al (2013). Estimating the heritability of reporting stressful life events captured by common genetic variants. Psychol Med 43: 1965–1971. · DOI
- Quast C, Altmann A, Weber P, Arloth J, Bader D, Heck A et al (2012). Rare variants in TMEM132D in a case-control sample for panic disorder. Am J Med Genet B Neuropsychiatr Genet 159B: 896–907. · DOI
- Reinelt E, Aldinger M, Stopsack M, Schwahn C, John U, Baumeister SE et al (2014). High social support buffers the effects of 5-HTTLPR genotypes within social anxiety disorder. Eur Arch Psychiatry Clin Neuroscience 264: 433–439. · DOI
- Roberson-Nay R, Eaves LJ, Hettema JM, Kendler KS, Silberg JL (2012). Childhood separation anxiety disorder and adult onset panic attacks share a common genetic diathesis. Depress Anxiety 29: 320–327. · DOI
- Rogers J, Raveendran M, Fawcett GL, Fox AS, Shelton SE, Oler JA et al (2013). CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression. Mol Psychiatry 18: 700–707. · DOI
- Roy MA, Neale MC, Pedersen NL, Mathe AA, Kendler KS (1995). A twin study of generalized anxiety disorder and major depression. Psychol Med 25: 1037–1049. · DOI · Paper page
- Rucker JJ, Breen G, Pinto D, Pedroso I, Lewis CM, Cohen-Woods S et al (2013). Genome-wide association analysis of copy number variation in recurrent depressive disorder. Mol Psychiatry 18: 183–189. · DOI · Paper page
- Sah R, Geracioti TD (2013). Neuropeptide Y and posttraumatic stress disorder. Mol Psychiatry 18: 646–655. · DOI · Paper page
- Savage JE, McMichael O, Gorlin EI, Beadel JR, Teachman B, Vladimirov VI et al (2015). Validation of candidate anxiety disorder genes using a carbon dioxide challenge task. Biol Psychol 109: 61–66. · DOI
- Scaini S, Ogliari A, Eley TC, Zavos HM, Battaglia M (2012). Genetic and environmental contributions to separation anxiety: a meta-analytic approach to twin data. Depress Anxiety 29: 754–761. · DOI
- Schuhmacher A, Lennertz L, Wagner M, Hofels S, Pfeiffer U, Guttenthaler V et al (2013). A variant of the neuronal amino acid transporter SLC6A15 is associated with ACTH and cortisol responses and cognitive performance in unipolar depression. Int J Neuropsychopharmacol 16: 83–90. · DOI
- Schuhmacher A, Mossner R, Hofels S, Pfeiffer U, Guttenthaler V, Wagner M et al (2011). PCLO rs2522833 modulates HPA system response to antidepressant treatment in major depressive disorder. Int J Neuropsychopharmacol 14: 237–245. · DOI
- Schur EA, Noonan C, Buchwald D, Goldberg J, Afari N (2009). A twin study of depression and migraine: evidence for a shared genetic vulnerability. Headache 49: 1493–1502. · DOI
- Service SK, Verweij KJ, Lahti J, Congdon E, Ekelund J, Hintsanen M et al (2012). A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. Transl Psychiatry 2: e116. · DOI
- Sharpley CF, Palanisamy SK, Glyde NS, Dillingham PW, Agnew LL (2014). An update on the interaction between the serotonin transporter promoter variant (5-HTTLPR), stress and depression, plus an exploration of non-confirming findings. Behav Brain Res 273: 89–105. · DOI
- Sheikh HI, Kryski KR, Smith HJ, Hayden EP, Singh SM (2013). Corticotropin-releasing hormone system polymorphisms are associated with children's cortisol reactivity. Neuroscience 229: 1–11. · DOI
- Sipila T, Kananen L, Greco D, Donner J, Silander K, Terwilliger JD et al (2010). An association analysis of circadian genes in anxiety disorders. Biol Psychiatry 67: 1163–1170. · DOI
- Smoller J, Cerrato F, Weatherall S (2015) The genetics of anxiety disorders. In: Pine D, Rothbaum B, Ressler K, Muskin A (eds). Anxiety Disorders: Translational Perspectives on Diagnosis and Treatment. Oxford University Press: Oxford, UK, pp 47–61. · doi:10.1093/med/9780199395125.003.0004
- Smoller JW (2011). Who's afraid of anxiety genetics? Biol Psychiatry 69: 506–507. · DOI
- Smoller JW (2013). Disorders and borders: psychiatric genetics and nosology. Am J Med Genet B Neuropsychiatr Genet 162B: 559–578. · DOI
- Smoller JW (2014). Psychiatric genetics and the future of personalized treatment. Depress Anxiety 31: 893–898. · DOI
- Smoller JW, Acierno JS Jr, Rosenbaum JF, Biederman J, Pollack MH, Meminger S et al (2001). Targeted genome screen of panic disorder and anxiety disorder proneness using homology to murine QTL regions. Am J Med Genet 105: 195–206. · DOI
- Smoller JW, Block SR, Young MM (2009). Genetics of anxiety disorders: the complex road from DSM to DNA. Depress Anxiety 26: 965–975. · DOI
- Smoller JW, Finn CT (2003). Family, twin, and adoption studies of bipolar disorder. Am J Med Genet C Semin Med Genet 123: 48–58. · DOI · Paper page
- Smoller JW, Gallagher PJ, Duncan LE, McGrath LM, Haddad SA, Holmes AJ et al (2014). The human ortholog of acid-sensing ion channel gene ASIC1a is associated with panic disorder and amygdala structure and function. Biol Psychiatry. 76: 902–910. · DOI
- Smoller JW, Gardner-Schuster E, Covino J (2008a). The genetic basis of panic and phobic anxiety disorders. Am J Med Genet C Semin Med Genet 148C: 118–126. · DOI
- Smoller JW, Paulus MP, Fagerness JA, Purcell S, Yamaki LH, Hirshfeld-Becker D et al (2008b). Influence of RGS2 on anxiety-related temperament, personality, and brain function. Arch Gen Psychiatry 65: 298–308. · DOI
- Smoller JW, Perlis RH (2004) Family and genetic studies of depression. In: Alpert JE, Fava M (eds). Handbook of Chronic Depression. Marcel Dekker, Inc.: New York, pp 97–138.
- Solovieff N, Cotsapas C, Lee PH, Purcell SM, Smoller JW (2013). Pleiotropy in complex traits: challenges and strategies. Nat Rev Genet 14: 483–495. · DOI · Paper page
- Solovieff N, Roberts AL, Ratanatharathorn A, Haloosim M, De Vivo I, King AP et al (2014). Genetic association analysis of 300 genes identifies a risk haplotype in SLC18A2 for post-traumatic stress disorder in two independent samples. Neuropsychopharmacology 39: 1872–1879. · DOI
- Song GG, Kim JH, Lee YH (2013). Genome-wide pathway analysis in major depressive disorder. J Mol Neurosci 51: 428–436. · DOI
- Stein MB, Jang KL, Taylor S, Vernon PA, Livesley WJ (2002). Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study. Am J Psychiatry 159: 1675–1681. · DOI · Paper page
- Stein MB, Keshaviah A, Haddad SA, Van Ameringen M, Simon NM, Pollack MH et al (2014). Influence of RGS2 on sertraline treatment for social anxiety disorder. Neuropsychopharmacology 39: 1340–1346. · DOI
- Stein MB, Walker JR, Anderson G, Hazen AL, Ross CA, Eldridge G et al (1996). Childhood physical and sexual abuse in patients with anxiety disorders and in a community sample. Am J Psychiatry 153: 275–277. · DOI · Paper page
- Stevens JS, Almli LM, Fani N, Gutman DA, Bradley B, Norrholm SD et al (2014). PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus. Proc Natl Acad Sci USA 111: 3158–3163. · DOI
- Sullivan PF (2007). Spurious genetic associations. Biol Psychiatry 61: 1121–1126. · DOI · Paper page
- Sullivan PF (2010). The psychiatric GWAS consortium: big science comes to psychiatry. Neuron 68: 182–186. · DOI · Paper page
- Sullivan PF, de Geus EJ, Willemsen G, James MR, Smit JH, Zandbelt T et al (2009). Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry 14: 359–375. · DOI · Paper page
- Sumner JA, McLaughlin KA, Walsh K, Sheridan MA, Koenen KC (2014). CRHR1 genotype and history of maltreatment predict cortisol reactivity to stress in adolescents. Psychoneuroendocrinology 43: 71–80. · DOI
- Tambs K, Czajkowsky N, Roysamb E, Neale MC, Reichborn-Kjennerud T, Aggen SH et al (2009a). Structure of genetic and environmental risk factors for dimensional representations of DSM-IV anxiety disorders. Br J Psychiatry 195: 301–307. · DOI
- Tambs K, Ronning T, Prescott CA, Kendler KS, Reichborn-Kjennerud T, Torgersen S et al (2009b). The Norwegian Institute of Public Health twin study of mental health: examining recruitment and attrition bias. Twin Res Human Genet 12: 158–168. · DOI · Paper page
- Taugher RJ, Lu Y, Wang Y, Kreple CJ, Ghobbeh A, Fan R et al (2014). The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis. J Neurosci 34: 10247–10255. · DOI
- Trzaskowski M, Eley TC, Davis OS, Doherty SJ, Hanscombe KB, Meaburn EL et al (2013). First genome-wide association study on anxiety-related behaviours in childhood. PLoS One 8: e58676. · DOI
- Tsuang MT, Faraone SV (1990) The Genetics of Mood Disorders. The Johns Hopkins University Press: Baltimore.
- Tyrka AR, Price LH, Gelernter J, Schepker C, Anderson GM, Carpenter LL (2009). Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity. Biol Psychiatry 66: 681–685. · DOI · Paper page
- Uddin M, Chang SC, Zhang C, Ressler K, Mercer KB, Galea S et al (2013). Adcyap1r1 genotype, posttraumatic stress disorder, and depression among women exposed to childhood maltreatment. Depress anxiety 30: 251–258. · DOI
- Uher R, McGuffin P (2008). The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry 13: 131–146. · DOI · Paper page
- Vaudry D, Falluel-Morel A, Bourgault S, Basille M, Burel D, Wurtz O et al (2009). Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev 61: 283–357. · DOI · Paper page
- Vinkhuyzen AA, Pedersen NL, Yang J, Lee SH, Magnusson PK, Iacono WG et al (2012). Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. Transl Psychiatry 2: e102. · DOI · Paper page
- Wadell PM, Hagerman RJ, Hessl DR (2013). Fragile X syndrome: psychiatric manifestations, assessment and emerging therapies. Curr Psychiatry Rev 9: 53–58.
- Walter S, Glymour MM, Koenen K, Liang L, Tchetgen Tchetgen EJ, Cornelis M et al (2013). Performance of polygenic scores for predicting phobic anxiety. PLoS One 8: e80326. · DOI
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Metadata
- Authors
- Smoller, J. W.
- Venue
- Neuropsychopharmacology
- Published
- 2015-08-31
- Volume
- 41
- Issue
- 1
- Pages
- 297-319
- ISSN
- 0893-133X (ISSN-L)
- 1740-634X
- OpenAlex
- W1840860792
- Cited by
- 480
- References
- 60
- FWCI
- 20.15
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.springer.com/tdm (tdm)
- www.springer.com/tdm (vor)
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