Mitochondria in innate immune responses

How mitochondria produce reactive oxygen species

Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207

A role for mitochondria in nlrp3 inflammasome activation

Zhou, R., Yazdi, A. S., Menu, P., & Tschopp, J. (2011) · Nature · doi:10.1038/nature09663 · Cited by 5,602

Circulating mitochondrial DAMPs cause inflammatory responses to injury

Zhang, Q., Raoof, M., Chen, Y., Sumi, Y., Sursal, T., Junger, W., Brohi, K., Itagaki, K., & Hauser, C. J. (2010) · Nature · doi:10.1038/nature08780 · Cited by 3,812

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Ishikawa, H., & Barber, G. N. (2008) · Nature · doi:10.1038/nature07317 · Cited by 3,576

Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

Seth, R. B., Sun, L., Ea, C.-K., & Chen, Z. J. (2005) · Cell · doi:10.1016/j.cell.2005.08.012 · Cited by 3,329

NOX enzymes and the biology of reactive oxygen

Lambeth, J. D. (2004) · Nature Reviews Immunology · doi:10.1038/nri1312 · Cited by 3,125

Sterile inflammation: sensing and reacting to damage

Chen, G. Y., & Nuñez, G. (2010) · Nature Reviews Immunology · doi:10.1038/nri2873 · Cited by 3,051

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Nakahira, K., Haspel, J. A., Rathinam, V. A. K., Lee, S.-J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., et al. (2011) · Nature Immunology · doi:10.1038/ni.1980 · Cited by 3,049

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Kawai, T., Takahashi, K., Sato, S., Coban, C., Kumar, H., Kato, H., Ishii, K. J., Takeuchi, O., & Akira, S. (2005) · Nature Immunology · doi:10.1038/ni1243 · Cited by 2,562

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

de Brito, O. M., & Scorrano, L. (2008) · Nature · doi:10.1038/nature07534 · Cited by 2,442

Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone mediates Ca+2 dysregulation, mitochondrial dysfunction, and apoptosis in human peripheral blood lymphocytes

Kushwaha, A., & Agarwal, V. K. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e21462 · Cited by 16

Sika Deer Velvet Antler Peptide Exerts Neuroprotective Effect in a Parkinson’s Disease Model via Regulating Oxidative Damage and Gut Microbiota

Liu, Y., Li, H., Yang, M., Guo, J., Sun, Z., Wang, S., Li, R., Pang, X., Kim, Y., Wang, X., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17070972 · Cited by 17

Mitochondria-dependent innate immunity: A potential therapeutic target in Flavivirus infection

Losarwar, S., Pancholi, B., Babu, R., & Garabadu, D. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114551 · Cited by 16

Inhibitors of Apoptosis Protein Antagonists (Smac Mimetic Compounds) Control Polarization of Macrophages during Microbial Challenge and Sterile Inflammatory Responses

Nadella, V., Mohanty, A., Sharma, L., Yellaboina, S., Mollenkopf, H., Mazumdar, V. B., Palaparthi, R., Mylavarapu, M. B., Maurya, R., Kurukuti, S., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01792 · Cited by 16

Respiratory Syncytial Virus-Induced Oxidative Stress in Lung Pathogenesis

Hosakote, Y. M., & Rayavara, K. (2019) · Springer eBooks · doi:10.1007/978-981-32-9366-3_13 · Cited by 16

Identification of antigenic domains and peptides from VP15 of white spot syndrome virus and their antiviral effects in Marsupenaeus japonicus

Boonyakida, J., Xu, J. C., Satoh, J., Nakanishi, T., Mekata, T., Kato, T., & Park, E. Y. (2021) · Scientific Reports · doi:10.1038/s41598-021-92002-8 · Cited by 16

Yersinia pestis -Induced Mitophagy That Balances Mitochondrial Homeostasis and mROS-Mediated Bactericidal Activity

Jiao, Y., Cao, S., Zhang, Y., Tan, Y., Zhou, Y., Wang, T., You, Y., Chen, H., Ren, Y., Yang, R., et al. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.00718-22 · Cited by 17

Caspase-8 and FLIP Regulate RIG-I/MDA5-induced Innate Immune Host Responses to Picornaviruses

Buskiewicz, I. A., Koenig, A., Huber, S. A., & Budd, R. C. (2012) · Future Virology · doi:10.2217/fvl.12.115 · Cited by 16

Genome-wide gene expression analysis of amphioxus ( Branchiostoma belcheri ) following lipopolysaccharide challenge using strand-specific RNA-seq

Zhang, Q., Zhu, Q., Xie, Z., Xu, B., Wang, X., & Chen, J. (2017) · RNA Biology · doi:10.1080/15476286.2017.1367890 · Cited by 16

Epicutaneous administration of the pattern recognition receptor agonist polyinosinic‐polycytidylic acid activates the MDA5/MAVS pathway in Langerhans cells

Tajpara, P., Schuster, C., Schön, E., Kienzl, P., Vierhapper, M. F., Mildner, M., & Elbe‐Bürger, A. (2018) · The FASEB Journal · doi:10.1096/fj.201701090r · Cited by 16

Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus

Downey, J., Randolph, H. E., Pernet, E., Tran, K. A., Khader, S. A., King, I. L., Barreiro, L. B., & Divangahi, M. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110974 · Cited by 15

Developmental Stage-Dependent Changes in Mitochondrial Function in the Brain of Offspring Following Prenatal Maternal Immune Activation

Cieślik, M., Zawadzka, A., Czapski, G. A., Wilkaniec, A., & Adamczyk, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087243 · Cited by 15

Radiosensitizing effects of pyrogallol-loaded mesoporous or-ganosilica nanoparticles on gastric cancer by amplified ferroptosis

Wang, H., Niu, H., Luo, X., Zhu, N., Xiang, J., He, Y., Chen, Z., Li, G., & Hu, Y. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1171450 · Cited by 15

Protective effect of Platycodon grandiflorus polysaccharide on apoptosis and mitochondrial damage induced by pseudorabies virus in PK-15 cells

Xing, Y., Cui, Y., Xu, G., Qi, C., Zhang, M., Cheng, G., Liu, Y., & Liu, J. (2023) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-023-01141-4 · Cited by 15

Trafficking and effect of released DNA on cGAS-STING signaling pathway and cardiovascular disease

Zhou, Z., Ouyang, C., Chen, Q., Ren, Z., Guo, X., Lei, M., Liu, C., & Yang, X. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1287130 · Cited by 15

Glaesserella parasuis serotype 5 induces pyroptosis via the RIG-I/MAVS/NLRP3 pathway in swine tracheal epithelial cells

Li, Y., Guo, M., Wáng, Q., Zhou, H., Wu, W., Lin, H., & Fan, H. (2024) · Veterinary Microbiology · doi:10.1016/j.vetmic.2024.110127 · Cited by 15

ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer

Stojanovic, L., Abbotts, R., Tripathi, K. K., Coon, C. M., Rajendran, S., Farid, E. A., Hostetter, G. H., Guarnieri, J. W., Wallace, D. C., Liu, S., et al. (2025) · Cancer Research · doi:10.1158/0008-5472.can-24-1286 · Cited by 15

Transgenerational inheritance of mitochondrial hormetic oxidative stress mediated by histone H3K4me3 and H3K27me3 modifications

Li, Y., Wang, C., Fu, X., Wu, D., He, C., Dai, W., Yue, X., Luo, Z., Yang, J., & Wan, Q.-L. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103598 · Cited by 16

Approaching a Unified Theory for Particle-Induced Inflammation

Bunderson‐Schelvan, M., Hamilton, R. F., Trout, K. L., Jessop, F., Gulumian, M., & Holian, A. (2015) · Current topics in environmental health and preventive medicine · doi:10.1007/978-4-431-55732-6_3 · Cited by 15

Dysregulated NADPH Oxidase Promotes Bone Damage in Murine Model of Autoinflammatory Osteomyelitis

Kralova, J. S., Drobek, A., Procházka, J., Špoutil, F., Fabišik, M., Glatzová, D., Borna, Š., Pokorna, J., Skopcova, T., Angelisová, P., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1900953 · Cited by 16

Evaluation of the Effect of the Intensity and Occurrence of Postoperative Pain of Resin-Based and Bioceramic Root Canal Sealers: A Systematic Review and Meta-Analysis of Randomized Controlled Trial Studies

Jamali, S., Darvish, M., Nasrabadi, N., & Jafarizadeh, S. (2021) · Pesquisa Brasileira em Odontopediatria e Clínica Integrada · doi:10.1590/pboci.2021.082 · Cited by 15

Regulatory Mechanisms and Functional Roles of Hypoxia-Induced Long Non-Coding RNA MTORT1 in Breast Cancer Cells

Cheng, Y., Su, L.-Y., Chen, L., Lu, T., Chuang, E. Y.-Y., Tsai, M., Chuang, L.-L., & Lai, L. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.663114 · Cited by 15

Positive Selection Drives the Adaptive Evolution of Mitochondrial Antiviral Signaling (MAVS) Proteins-Mediating Innate Immunity in Mammals

Ahmad, H. I., Afzal, G., Iqbal, M. N., Iqbal, M. A., Shokrollahi, B., Mansoor, M. K., & Chen, J. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.814765 · Cited by 15

Roles of mitochondrial DNA in dynamics of the immune response to COVID-19

Mahmoodpoor, A., Sanaie, S., Ostadi, Z., Eskandari, M., Behrouzi, N., Asghari, R., Zahirnia, A., Sohrabifar, N., & Kazeminasab, S. (2022) · Gene · doi:10.1016/j.gene.2022.146681 · Cited by 15

Targeting Oxidative Stress in Stroke

Bach, A. (2017) · Springer series in translational stroke research · doi:10.1007/978-3-319-45345-3_8 · Cited by 15

Evidence that a mitochondrial death spiral underlies antagonistic pleiotropy

Stern, M. (2017) · Aging Cell · doi:10.1111/acel.12579 · Cited by 16

Subcellular localization and function study of a secreted phospholipase C from Nocardia seriolae

Xia, L., Liang, H., Xu, L., Chen, J., Bekaert, M., Zhang, H., & Lu, Y. (2017) · FEMS Microbiology Letters · doi:10.1093/femsle/fnx143 · Cited by 15

Association between the T6459C point mutation of the mitochondrial MT ‐ CO 1 gene and susceptibility to sepsis among Chinese Han people

Shen, X., Han, G., Li, S., Song, Y., Shen, H., Zhai, Y., Wang, Y., Zhang, F., Dong, N., Li, T., et al. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13746 · Cited by 15

Drp1-dependent mitochondrial fission regulates p62-mediated autophagy in LPS-induced activated microglial cells

Chae, U., Kim, H. S., Lee, H., Lee, S., & Lee, D. (2018) · Bioscience Biotechnology and Biochemistry · doi:10.1080/09168451.2018.1549933 · Cited by 15

TCAIM Decreases T Cell Priming Capacity of Dendritic Cells by Inhibiting TLR-Induced Ca2+ Influx and IL-2 Production

Vogel, S., Schlickeiser, S., Jürchott, K., Akyuez, L., Schumann, J., Appelt, C., Vogt, K., Schröder, M., Vaeth, M., Berberich‐Siebelt, F., et al. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1400713 · Cited by 17

Hemocytes in blue mussel Mytilus edulis adopt different energy supply modes to cope with different BDE-47 exposures

Jiang, Y., Cao, S., Zhou, B., Cao, Q., Xu, M., Sun, T., Zhao, X., Zhou, Z., & Wang, Y. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.163766 · Cited by 14

The molecular mechanism of macrophage-adipocyte crosstalk in maintaining energy homeostasis

Zhang, Y., Zhang, B., & Sun, X. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1378202 · Cited by 17

Fungal burden, dimorphic transition and candidalysin: Role in Candida albicans-induced vaginal cell damage and mitochondrial activation in vitro

Spaggiari, L., Ardizzoni, A., Ricchi, F., Pedretti, N., Ramos, C. A. S., Ramos, G. B. S., Kenno, S., Seta, F. D., & Pericolini, E. (2024) · PLoS ONE · doi:10.1371/journal.pone.0303449 · Cited by 14

Arsenic-induced mtDNA release promotes inflammatory responses through cGAS-STING signaling in chicken hepatocytes

Pan, H., Su, Q., Hong, P., You, Y., Zhou, L., Zou, J., Sun, J., Zhong, G., Liao, J., Zhang, H., et al. (2024) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2024.106129 · Cited by 14

Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems

Wen, R. M., Umeano, A. C., Francis, L., Sharma, N. D., Tundup, S., & Dhar, S. (2016) · Vaccines · doi:10.3390/vaccines4020018 · Cited by 14

Reduction in the Level of Plasma Mitochondrial DNA in Human Diving, Followed by an Increase in the Event of an Accident

Blatteau, J.-É., Gaillard, S., de Maistre, S., Richard, S., Louges, P., Gempp, E., Druelles, A., Lehot, H., Morin, J. E., Castagna, O., et al. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01695 · Cited by 14

RNA-seq profiling, and impaired autophagic process in skeletal muscle of MELAS

Deng, J., Lu, Y., Xie, Z., Liu, J., Yuan, Y., & Wang, Z. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.12.005 · Cited by 14

Design, Synthesis and Biological Evaluation of Ferrocenyl Thiazole and Thiazolo[5,4-d]thiazole Catechols as Inhibitors of 5-hLOX and as Antibacterials against Staphylococcus aureus. Structural Relationship and Computational Studies

Flores, E., Muñoz-Osses, M., Torrent, C., Vásquez‐Martínez, Y., Gómez, A., Martín, M. C., Vega, A. I., Martı́, A. A., Godoy, F., & Mascayano, C. (2020) · Organometallics · doi:10.1021/acs.organomet.0c00284 · Cited by 14

Pathway Based Analysis of Genes and Interactions Influencing Porcine Testis Samples from Boars with Divergent Androstenone Content in Back Fat

Sahadevan, S., Gunawan, A., Tholen, E., Große‐Brinkhaus, C., Tesfaye, D., Schellander, K., Hofmann‐Apitius, M., Çınar, M. U., & Uddin, M. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091077 · Cited by 14

SIV-Induced Immune Activation and Metabolic Alterations in the Dorsal Root Ganglia During Acute Infection

Mangus, L. M., Weinberg, R. L., Knight, A. C., Queen, S. E., Adams, R. J., & Mankowski, J. L. (2018) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nly111 · Cited by 14

Transcriptional profiles and copper stress responses in zebrafish cox17 mutants

Sun, H., Chen, M., Wang, Z., Zhao, G., & Liu, J. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.113364 · Cited by 14

Condensin II protein dysfunction impacts mitochondrial respiration and stress response

Deutschman, E., Ward, J. R., Kumar, A., Ray, G., Welch, N., Lemieux, M. E., Dasarathy, S., & Longworth, M. S. (2019) · Journal of Cell Science · doi:10.1242/jcs.233783 · Cited by 14

Yin and Yang of mitochondrial ROS in Drosophila

Towarnicki, S. G., Kok, L. M., & Ballard, J. W. O. (2020) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2020.104022 · Cited by 15

IRF3 deficiency impacts granzyme B expression and maintenance of memory T cell function in response to viral infection

Moore, T. C., Vogel, A. J., Petro, T. M., & Brown, D. M. (2015) · Microbes and Infection · doi:10.1016/j.micinf.2015.03.001 · Cited by 14

CARD19 Interacts with Mitochondrial Contact Site and Cristae Organizing System Constituent Proteins and Regulates Cristae Morphology

Rios, K. E., Zhou, M., Lott, N. M., Beauregard, C. R., McDaniel, D. P., Conrads, T. P., & Schaefer, B. C. (2022) · Cells · doi:10.3390/cells11071175 · Cited by 13

Resveratrol Attenuates the Mitochondrial RNA-Mediated Cellular Response to Immunogenic Stress

Yoon, J., Ku, D., Lee, M.-S., Lee, N., Im, S. G., & Kim, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087403 · Cited by 13

Therapeutic strategies to ameliorate mitochondrial oxidative stress in ischaemia-reperfusion injury: A narrative review

Alotaibi, K., Arulkumaran, N., Dyson, A., & Singer, M. (2025) · Clinical Science · doi:10.1042/cs20242074 · Cited by 14

Bovine herpesvirus type 5 infection regulates Bax/BCL-2 ratio

Garcia, A. A. F., Novais, J. B., Antello, T. F., Silva-Frade, C., Ferrarezi, M. C., Flores, E. F., & Cardoso, T. C. (2013) · Genetics and Molecular Research · doi:10.4238/2013.september.23.8 · Cited by 13

Coronary microvascular and endothelial function regulation: Crossroads of psychoneuroendocrine immunitary signals and quantum physics [Part B]

Lin, C. D., Poretto, A., Scodro, M., Marra, M. P., Iliceto, S., & Tona, F. (2015) · Journal of Integrative Cardiology · doi:10.15761/jic.1000136 · Cited by 13

Parkin-mediated responses against infection and wound involve TSPO-VDAC complex in Drosophila

Cho, J., Park, J. H., Chung, C. G., Shim, H.-J., Jeon, K. H., Yu, S., & Lee, S. B. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.05.006 · Cited by 13

Modulation of Mitochondria During Viral Infections

Reshi, L., Wang, H., & Hong, J. (2018) · InTech eBooks · doi:10.5772/intechopen.73036 · Cited by 13

Herpesvirus Regulation of Selective Autophagy

Vo, M. T., & Choi, Y. B. (2021) · Viruses · doi:10.3390/v13050820 · Cited by 13

On the offense and defense: mitochondrial recovery programs amidst targeted pathogenic assault

Mahmud, S. A., Qureshi, M. A., & Pellegrino, M. W. (2021) · FEBS Journal · doi:10.1111/febs.16126 · Cited by 13

Adenosine Triphosphate in Serum as a Promising Biomarker for Differential Diagnosis of Hepatitis B Disease Progression

Lin, C., Huang, Y., Luo, L., Fang, F., Zhang, J., Xun, Z., Fu, Y., Shang, H., Liu, C., & Ou, Q. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.927761 · Cited by 13

Modulation of human endogenous retroviruses and cytokines expression in peripheral blood mononuclear cells from autistic children and their parents

Cipriani, C., Giudice, M., Petrone, V., Fanelli, M., Minutolo, A., Miele, M. T., Toschi, N., Maracchioni, C., Siracusano, M., Benvenuto, A., et al. (2022) · Retrovirology · doi:10.1186/s12977-022-00603-6 · Cited by 14

Mitochondria in Multi-Directional Differentiation of Dental-Derived Mesenchymal Stem Cells

Liu, H., Xu, K., He, Y., & Huang, F. P. (2023) · Biomolecules · doi:10.3390/biom14010012 · Cited by 13

Agitation by Suffocation: How Hypoxia Activates Innate Immunity via the Warburg Effect

Wen, H., & Ting, J. P. ‐. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.05.016 · Cited by 13

Transcriptional differences between coronavirus disease 2019 and bacterial sepsis

Ito, H., Ishikawa, M., Matsumoto, H., Sugihara, F., Okuzaki, D., Hirata, H., & Ogura, H. (2022) · Virology Journal · doi:10.1186/s12985-022-01930-y · Cited by 12

Targeted mitochondrial fluorescence probe with large stokes shift for detecting viscosity changes in vivo and in ferroptosis process

Tan, M., Li, W., He, H., Wang, J., Chen, Y., Guo, Y., Lin, T., & Ke, F. (2024) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2024.124246 · Cited by 12

Single-cell mitochondrial DNA sequencing: Methodologies and applications

Zhou, G., Gu, Z., & Xu, J. (2024) · Mitochondrial Communications · doi:10.1016/j.mitoco.2024.10.001 · Cited by 12

Global transcription analysis of vaccinated channel catfish following challenge with virulent Edwardsiella ictaluri

Pridgeon, J. W., Yeh, H., Shoemaker, C. A., & Klesius, P. H. (2012) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2012.01.022 · Cited by 12

Mitochondrial reactive oxygen species regulate fungal protease-induced inflammatory responses

Kim, Y. H., & Lee, S. (2017) · Toxicology · doi:10.1016/j.tox.2017.01.008 · Cited by 12

A novel therapeutics agent: antioxidant effects of hydroxylfasudil on rat kidney and liver tissues in a protamine sulphate-induced cystitis rat model; preliminary results

Bozkurt, A., Budak, H., Erol, H. S., Can, S., Mercantepe, T., Akın, Y., Özbey, İ., Çankaya, M., Halici, M., & Çoban, T. A. (2018) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2018.1449120 · Cited by 12

Neospora caninum Evades Immunity via Inducing Host Cell Mitophagy to Inhibit Production of Proinflammatory Cytokines in a ROS-Dependent Manner

Zhang, X., Wang, Y., Gong, P., Wang, X., Zhang, N., Chen, M., Wei, R., Zhang, X., Li, X., & Li, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.827004 · Cited by 12

Mitochondria-targeted nanoplatforms building for in situ ROS generating photodynamic tumor therapy through reinforcing mitochondria apoptotic pathway

Wang, Z., Liu, F., Liu, Y., Huyan, Y., Mehdi, M., Xu, Y., Li, H., & Sun, S. (2022) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2022.129973 · Cited by 12

Legionella and mitochondria, an intriguing relationship

García-Rodríguez, F. J., Buchrieser, C., & Escoll, P. (2022) · International review of cytology · doi:10.1016/bs.ircmb.2022.10.001 · Cited by 12

Role of UPRmt and mitochondrial dynamics in host immunity: it takes two to tango

Kumar, M., Sharma, S., & Mazumder, S. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1135203 · Cited by 13

Impact of Engineered Expression of Mitochondrial Association Factor 1b onToxoplasma gondiiInfection and the Host Response in a Mouse Model

English, E. D., & Boyle, J. P. (2018) · mSphere · doi:10.1128/msphere.00471-18 · Cited by 12

In situ and ex situ surface‐enhanced Raman spectroscopy (SERS) analysis of cell mitochondria

Yue, J., Shen, Y., Liang, L., Cong, L., Guan, X., Li, Z., Xu, S., Liang, C., Shi, W., & Xu, W. (2020) · Journal of Raman Spectroscopy · doi:10.1002/jrs.5820 · Cited by 12

Programming and memory dynamics of innate leukocytes during tissue homeostasis and inflammation

Lee, C., Geng, S., Zhang, Y., Rahtes, A., & Li, L. (2017) · Journal of Leukocyte Biology · doi:10.1189/jlb.6mr0117-027rr · Cited by 13

Mitochondrial DNA damage in HIV infection: a mechanistic driver of immunometabolic dysfunction and chronic inflammation

Ma, L., Wang, X., & XU, H. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1722463 · Cited by 11

Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models

Jett, K., Baker, Z. N., Hossain, A., Boulet, A., Cobine, P. A., Ghosh, S., Ng, P., Yilmaz, O., Barreto, K., DeCoteau, J. F., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci154684 · Cited by 12

Intracellular delivery of piezotronic-dominated nanocatalysis to mimic mitochondrial ROS generation for powering macrophage immunotherapy

Feng, J., Liu, X., Li, K., Zhao, W., Wang, W., Ge, S., Liu, H., & Li, J. (2024) · Nano Energy · doi:10.1016/j.nanoen.2024.109287 · Cited by 11

A lipid droplet-targeted fluorescent probe for fluorescence imaging of cell and zebrafish viscosity

Zheng, H., Li, G., Zhang, L., Fan, M., & Lin, W. (2024) · New Journal of Chemistry · doi:10.1039/d4nj02986k · Cited by 11

Open questions: seeking a holistic approach for mitochondrial research

McBride, H. M. (2015) · BMC Biology · doi:10.1186/s12915-015-0120-x · Cited by 11

Preparation, chemical structure, and immunostimulatory activity of a water-soluble heteropolysaccharide from Suillus granulatus fruiting bodies

Gao, X., Zeng, R., Ho, C., Li, B., Chen, S., Xiao, C., Hu, H., Cai, M., Chen, Z., Xie, Y., et al. (2022) · Food Chemistry X · doi:10.1016/j.fochx.2022.100211 · Cited by 11

Analysis of Mitochondria by Single-Organelle Resolution

Harbauer, A. B., Schneider, A., & Wohlleber, D. (2022) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-061020-111722 · Cited by 12

Proteomic, Transcriptomic, Mutational, and Functional Assays Reveal the Involvement of Both THF and PLP Sites at the GmSHMT08 in Resistance to Soybean Cyst Nematode

Lakhssassi, N., Knizia, D., Baze, A. E., Lakhssassi, A., Meksem, J., & Meksem, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911278 · Cited by 11

Characterization and subcellular localization of Alongshan virus proteins

Zhao, Y., Wu, P., Liu, L., Ma, B., Pan, M., Huang, Y., Du, N., Yu, H., Sui, L., Wang, Z., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1000322 · Cited by 11

Chronic exposure to indoxacarb and pulmonary expression of toll-like receptor-9 in mice

Kaur, S., Mukhopadhyay, C. S., & Sethi, R. S. (2016) · Veterinary World · doi:10.14202/vetworld.2016.1282-1286 · Cited by 11

Hochuekkito, a Japanese Herbal Medicine, Restores Metabolic Homeostasis between Mitochondrial and Glycolytic Pathways Impaired by Influenza A Virus Infection

Takanashi, K., Dan, K., Kanzaki, S., Hasegawa, H., Watanabe, K., & Ogawa, K. (2017) · Pharmacology · doi:10.1159/000455918 · Cited by 11

The mtDNA replication-related genes TFAM and POLG are associated with leprosy in Han Chinese from Southwest China

Wang, D., Li, G.-D., Fan, Y., Zhang, D., Bi, R., Yu, X.-F., Long, H., Li, Y., & Yao, Y. (2017) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2017.09.001 · Cited by 11

Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function

Wu, Z., Koh, B., Lawrence, L. M., Kanamala, M., Pool, B., Svirskis, D. M., Dalbeth, N., Astin, J. W., Crosier, K. E., Crosier, P. S., et al. (2019) · Zebrafish · doi:10.1089/zeb.2018.1681 · Cited by 11

Mitochondrial DNA copy number and telomere length in peripheral blood mononuclear cells in comparison with whole blood in three different age groups

Zole, E., & Ranka, R. (2019) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2019.04.007 · Cited by 12

Recovery from discrete wound severities in side-blotched lizards (Uta stansburiana): implications for energy budget, locomotor performance, and oxidative stress

Hudson, S. B., Virgin, E. E., Brodie, E. D., & French, S. S. (2021) · Journal of Comparative Physiology B · doi:10.1007/s00360-021-01347-z · Cited by 11

Thermodynamics and Inflammation: Insights into Quantum Biology and Ageing

Nunn, A. V. W., Guy, G. W., & Bell, J. D. (2022) · Quantum Reports · doi:10.3390/quantum4010005 · Cited by 12

Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis‐independent NF ‐κ B activation

Ailenberg, M., Ciano‐Oliveira, C. D., Szászi, K., Dan, Q., Rozycki, M., Kapùs, A., & Rotstein, O. D. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13162 · Cited by 11

Heixuedian (heix), a potential melanotic tumor suppressor gene, exhibits specific spatial and temporal expression pattern during drosophila hematopoiesis

Xia, Y., Midoun, S. Z., Xu, Z., & Hong, L. (2014) · Developmental Biology · doi:10.1016/j.ydbio.2014.12.001 · Cited by 11

The mitochondrial genome: how it drives fertility

John, J. C. S., Srirattana, K., Tsai, T., & Sun, X. (2017) · Reproduction Fertility and Development · doi:10.1071/rd17408 · Cited by 11

Neutrophil-dependent Mitochondrial DNA Release Associated With Extracellular Trap Formation in Inflammatory Bowel Disease

Drury, B., Chuah, C. S., Hall, R., Hardisty, G. R., Rossi, A. G., & Ho, G. (2023) · Gastro Hep Advances · doi:10.1016/j.gastha.2023.03.022 · Cited by 10

Mitochondrial dysfunction at the cornerstone of inflammatory exacerbation in aged macrophages

Maurmann, R. M., Schmitt, B. L., Mosalmanzadeh, N., & Pence, B. D. (2023) · Exploration of Immunology · doi:10.37349/ei.2023.00112 · Cited by 12

A multi-adjuvant nanovaccine platform based on targeted delivery of specific antigens for cancer immunotherapy

Li, W., Zhang, Q., Ma, X., Zeng, X., & Zhang, X. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102481 · Cited by 10

Polyamine-Enriched Exosomes from Leishmania donovani Drive Host Macrophage Polarization via Immunometabolism Reprogramming

Sebastian, P., Namdeo, M., Devender, M., Anand, A., Kumar, K., Veronica, J., & Maurya, R. (2024) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.4c00738 · Cited by 10

Hydrogel delivering self-assembled herbal nanoparticles accelerates diabetic wound healing through mitochondrial regulation

Guo, J., Hu, B., Wei, Y. Z., Cheng, G., Wang, C., Qin, X., Chen, X., Chen, J., Chen, Z., & Chen, T. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102417 · Cited by 10

Emerging role of mitochondria in response to HBV infection

Lin, C., & Ou, Q. (2022) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.24704 · Cited by 10

Avian pathogenic Escherichia coli T6SS effector protein Hcp2a causes mitochondrial dysfunction through interaction with LETM1 protein in DF-1 cells

Lu, L., Zhao, Q., Chen, Z., Wang, H., Wei, X., Zhao, B., Wang, Z., Shao, Y., Tu, J., & Song, X. (2024) · Poultry Science · doi:10.1016/j.psj.2024.103514 · Cited by 10

When Our Best Friend Becomes Our Worst Enemy: The Mitochondrion in Trauma, Surgery, and Critical Illness

Torp, M., Stensløkken, K., & Vaage, J. (2024) · Journal of Intensive Care Medicine · doi:10.1177/08850666241237715 · Cited by 10

Multi-System-Level Analysis with RNA-Seq on Pterygium Inflammation Discovers Association between Inflammatory Responses, Oxidative Stress, and Oxidative Phosphorylation

Kim, Y.-A., Choi, Y., Kim, T. G., Jeong, J., Yu, S., Kim, T., Sheen, K., Lee, Y., Choi, T., Park, Y. H., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25094789 · Cited by 10

Label-free proteomic analysis of PBMCs reveals gender differences in response to long-term antiretroviral therapy of HIV

Zhang, L., Wang, Z., Chen, Y., Zhang, C., Xie, S., Cui, Y., & Wang, Z. (2015) · Journal of Proteomics · doi:10.1016/j.jprot.2015.05.033 · Cited by 10

Quantitative proteomic analyses provide insights into the hyalinocytes and granulocytes phagocytic killing of ivory shell Babylonia areolata in vitro

Di, G., Zhu, G., Chen, X., Miao, X., Li, M., Fu, J., Wang, N., Zhu, L., Huang, M., & Ke, C. (2021) · Aquaculture · doi:10.1016/j.aquaculture.2021.736898 · Cited by 10

Mitochondria as Molecular Platforms Integrating Multiple Innate Immune Signalings

Monlun, M., Hyernard, C., Blanco, P., Lartigue, L., & Faustin, B. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.10.028 · Cited by 88

Mitochondria, Oxidative Stress and Innate Immunity

Chen, Y., Zhou, Z., & Min, W. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01487 · Cited by 315

Mitochondria in innate immune signaling

Banoth, B., & Cassel, S. L. (2018) · Translational Research · doi:10.1016/j.trsl.2018.07.014 · Cited by 410

Mitochondrial reactive zones in antiviral innate immunity

Yasukawa, K., & Koshiba, T. (2021) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2020.129839 · Cited by 19

Mitochondria as a centrally positioned hub in the innate immune response

Sandhir, R., Halder, A., & Sunkaria, A. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.10.020 · Cited by 135