The DOI matches its Crossref record; 142 of the 142 references it cites were found in a registry or an index.
The origin and specification of cortical interneurons
Abstract
GABA-containing interneurons are crucial to both the development and function of the cerebral cortex. Unlike cortical projection neurons, which have a relatively conserved set of characteristics, interneurons include multiple phenotypes that vary on morphological, physiological and neurochemical axes. This diversity, and the relatively late, context-dependent maturation of defining features, has challenged efforts to uncover the transcriptional control of cortical interneuron development. Here, we discuss recent data that are beginning to illuminate the origins and specification of distinct subgroups of cortical interneurons.
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“Their 'parvalbumin' fate seems to be established at their origin, as the progenitors leave the cell cycle [127, 128].”
From Parvalbumin interneuron vulnerability and brain disorders (2021) · cites this paper as [127]
In the citing paper
“In contrast, Martinotti cells and 5-HT3AR-lacking O-LM cells arise from MGE progenitors with specification driven by the homeodomain transcription factor Nkx2.1 (10% of MGE-derived hippocampal interneurons based on assumptions outlined above combined with the fact that O-LMs represent 40% of SST interneurons) (102, 203, 651, 794, 1042, 1134, 1138, 1213).”
From Hippocampal GABAergic Inhibitory Interneurons (2017) · cites this paper as [1213]
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“We also observed that over-expression of Maf at the peak of PV neurogenesis (E14.5) (23) repress PV+ interneuron fates (fig. S24, D and E).”
From Early emergence of cortical interneuron diversity in the mouse embryo (2018) · cites this paper as [23]
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Patterning of ventral telencephalon requires positive function of Gli transcription factors
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“Following their generation, many MGE- and LGE-derived neurons undergo tangential migration to reach the cortex or olfactory bulb (Corbin et al., 2001; Marin and Rubenstein, 2001;Wonders and Anderson, 2006).”
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“In contrast, cortical inhibitory GABAergic interneurons are more diverse in terms of their proliferative origins and follow more complex migratory routes that are at times tangential to the cortical plate (Wonders and Anderson, 2006).”
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“Together, these results suggest that our modified protocol promotes the formation of MGE-like neural progenitors, which differentiate into GABAergic neurons expressing cIN markers, including PV or SST, which mark the two major subtypes of MGE-derived cINs.”
BackgroundInfluentialDirect Neuronal Reprogramming: Bridging the Gap Between Basic Science and Clinical Application
Vasan, L., Park, E., David, L. A., Fleming, T., & Schuurmans, C. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.681087 · Cited by 61
Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain
Chung, C., Yang, X., Hevner, R. F., Kennedy, K. L., Vong, K. I., Liu, Y., Patel, A. M., Nedunuri, R., Barton, S. T., Noël, G. P. J. C., et al. (2024) · Nature · doi:10.1038/s41586-024-07292-5 · Cited by 59
Reptiles: A New Model for Brain Evo‐Devo Research
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Transgenic labeling of parvalbumin-expressing neurons with tdTomato
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“Introduction Parvalbumin (PVALB) is a calcium-binding protein that is expressed in about 40–50% of GABAergic interneurons (Wonders and Anderson, 2006, Xu et al., 2010, Rudy et al., 2011).”
BackgroundLIS1 and DCX: Implications for Brain Development and Human Disease in Relation to Microtubules
Reiner, O. (2013) · Scientifica · doi:10.1155/2013/393975 · Cited by 63
“Most of the GABAergic neurons are born in the ventral part of the telencephalon, in the subpallium [61] (for reviews see [62–64]).”
Background5-HT6 Receptor: A New Player Controlling the Development of Neural Circuits
Dayer, A. G., Jacobshagen, M., Chaumont‐Dubel, S., & Marin, P. (2015) · ACS Chemical Neuroscience · doi:10.1021/cn500326z · Cited by 63
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“Although much progress has been made in understanding the development of the ventral telencephalon (Marín and Rubenstein, 2001; Wonders and Anderson, 2006), the molecular mechanism that differentiates striatal cholinergic interneurons from the cholinergic projection neurons in Ch1-4 remains to be elucidated.”
BackgroundTucker, E. S., Segall, S. K., Gopalakrishna, D., Wu, Y., Vernon, M., Polleux, F., & LaMantia, A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2341-08.2008 · Cited by 58
“Novel dimensions of LGE and MGE molecular diversity Most previously identified LGE- or MGErestricted genes encode transcription factors (Campbell, 2003; Takahashi and Liu, 2006; Wonders and Anderson, 2006).”
BackgroundErbin in Amygdala Parvalbumin-Positive Neurons Modulates Anxiety-like Behaviors
Luo, Z.-Y., Huang, L., Lin, S., Yin, Y., Jie, W., Hu, N.-Y., Hu, Y.-Y., Guan, Y., Liu, J., You, Q.-L., et al. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.10.021 · Cited by 57
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“GABA interneurons derive from subpallial NPCs residing in the medial (MGE) and lateral (LGE) ganglionic eminences, which migrate toward the cortex/hippocampus and olfactory bulb (OB), respectively (Wichterle et al., 2001; Marín and Rubenstein, 2003; Métin et al., 2006; Wonders and Anderson, 2006).”
Baltz, T. (2010) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2010.00015 · Cited by 59
Germain, N. D., Banda, E. C., Becker, S., Naegele, J. R., & Grabel, L. B. (2013) · Stem Cells and Development · doi:10.1089/scd.2012.0264 · Cited by 57
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Beyond the frontiers of neuronal types
Battaglia, D. A., Karagiannis, A., Gallopin, T., Gutch, H. W., & Cauli, B. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00013 · Cited by 61
“FS-PV and Adapting SOM neurons, both derived from the medial ganglionic eminence (Wonders and Anderson, 2006; Miyoshi et al., 2007), provide an example of such a developmental divergence.”
BackgroundMagueresse, C. L., Alfonso, J., Khodosevich, K. V., Martín, Á. A. A., Bark, C., & Monyer, H. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4273-11.2011 · Cited by 54
“Most inhibitory interneurons in the mouse neocortex are generated in restricted areas of the embryonic ventral telencephalon, known as the ganglionic eminence and the preoptic area (Anderson et al., 1997; Marín and Rubenstein, 2003; Wonders and Anderson, 2006; Gelman et al., 2009).”
BackgroundCortical interneuron function in autism spectrum condition
Lunden, J. W., Durens, M., Phillips, A. W., & Nestor, M. W. (2018) · Pediatric Research · doi:10.1038/s41390-018-0214-6 · Cited by 56
“The three major areas in the developing cortex that generate INs are the MGE, the CGE, and the POA.(48,49) The expression of regulatory transcription factors combined with spatiotemporal gradients of growth factors drives the expression of IN subtypes(48,49) Cortical interneuron function in autism spectrum condition J…”
BackgroundNeurogliaform cortical interneurons derive from cells in the preoptic area
Niquille, M., Limoni, G., Markopoulos, F., Cadilhac, C., Prados, J., Holtmaat, A., & Dayer, A. (2018) · eLife · doi:10.7554/elife.32017 · Cited by 55
Control of tangential/non-radial migration of neurons in the developing cerebral cortex
Nakajima, K. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.05.006 · Cited by 61
Hsu, R., Schofield, C. M., Cruz, C. G. D., Jones, D. M., Blelloch, R. H., & Ullian, E. M. (2012) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2012.06.002 · Cited by 55
“…demonstrate a selective loss of PV interneurons in the Dgcr8 fl/fl ;Cre PFC. BDNF and TrkB expression are reduced in the Dgcr8 fl/fl ;Cre PFC Maturation of interneuron subclasses is regulated by a combination of intrinsic molecular programs and extrinsic signaling cues (Wonders and Anderson, 2006).”
InfluentialDevelopmental interneuron subtype deficits after targeted loss of Arx
Marsh, E. D., Nasrallah, M. P., Walsh, C. E., Murray, K. A., Sunnen, C. N., McCoy, A. J., & Golden, J. A. (2016) · BMC Neuroscience · doi:10.1186/s12868-016-0265-8 · Cited by 55
Interneuron development and dysfunction
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Osório, J., Mueller, T., Rétaux, S., Vernier, P., & Wullimann, M. F. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22247 · Cited by 54
“…is a striking feature in the mouse brain and many details regarding the involvement of downstream genes that control neuronal differentiation in these two telencephalic regions are meanwhile known (reviews: Parnavelas 2000; Bertrand et al., 2002; Hevner 2006; Wonders and Anderson 2006).”
BackgroundMalik, R., Pai, E. L.-L., Rubin, A. N., Stafford, A. M., Angara, K., Minasi, P., Rubenstein, J. L. R., Sohal, V. S., & Vogt, D. L. (2019) · Nature Communications · doi:10.1038/s41467-019-12962-4 · Cited by 55
Huang, A. Y., Li, P., Rodin, R. E., Kim, S. N., Dou, Y., Kenny, C. J., Akula, S. K., Hodge, R. D., Bakken, T. E., Miller, J. A., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2006163117 · Cited by 50
“The human cerebral cortex has been thought to contain ∼80% excitatory glutamatergic neurons and 20% GABAergic interneurons (48), although recent scRNAseq studies have reported a somewhat lower ratio of about 70% excitatory neurons (SI Appendix, Table S3) (5, 49, 50).”
BackgroundCanetta, S. E., Holt, E. S., Benoit, L. J., Teboul, E., Sahyoun, G. M., Ogden, R. T., Harris, A. Z., & Kellendonk, C. (2022) · eLife · doi:10.7554/elife.80324 · Cited by 59
“Within the PFC, parvalbumin-expressing (PV) interneurons regulate the activity of excitatory cortical pyramidal neurons (Markram et al., 2004, Wonders and Anderson, 2006).”
BackgroundPhysiological and morphological characterization of GABAergic neurons in the medial amygdala
Bian, X. (2013) · Brain Research · doi:10.1016/j.brainres.2013.03.012 · Cited by 55
How can artificial neural networks approximate the brain?
Shao, F., & Shen, Z. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.970214 · Cited by 66
“The numbers of inhibitory interneurons have increased during phylogenetic evolution along with the appearance of unique interneuron subtypes in humans (Wonders and Anderson, 2006; Petanjek et al., 2008).”
BackgroundCai, Y., Zhang, Q., Wang, C., Zhang, Y., Ma, T., Zhou, X., Tian, M., Rubenstein, J. L. R., & Yang, Z. (2012) · The Journal of Comparative Neurology · doi:10.1002/cne.23186 · Cited by 53
“Rabbit polyclonal anti-CR recognizes a band of 31 kDa on western blot of rat brain (manufacturer’s technical information).”
BackgroundSp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development
Liu, Z., Zhang, Z., Lindtner, S., Li, Z., Xu, Z., Wei, S., Liang, Q., Wen, Y. F., Tao, G., You, Y., et al. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy133 · Cited by 53
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“Email: decurtis.ivan@hsr.it The intracellular mechanisms driving postmitotic development of cortical γ-aminobutyric acid (GABA)ergic interneurons are poorly understood.”
Inhibition in the auditory cortex
Studer, F., & Barkat, T. R. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.11.021 · Cited by 56
Nests of dividing neuroblasts sustain interneuron production for the developing human brain
Paredes, M. F., Mora, C., Flores-Ramirez, Q., Cebrián‐Silla, A., Dosso, A. D., Larimer, P., Chen, J., Kang, G., González-Granero, S., Garcia, E., et al. (2022) · Science · doi:10.1126/science.abk2346 · Cited by 50
“J. E. Long, I. Cobos, G. B. Potter, J. L. R. Rubenstein, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.”
InfluentialMeningeal defects alter the tangential migration of cortical interneurons in Foxc1 hith/hith mice
Zarbalis, K. S., Choe, Y., Siegenthaler, J. A., Orosco, L. A., & Pleasure, S. J. (2012) · Neural Development · doi:10.1186/1749-8104-7-2 · Cited by 52
“In rodents, most GABA (g-aminobutyric acid)-producing interneurons of the cerebral cortex originate in the medial ganglionic eminence of the ventral forebrain and migrate to their cortical destinations using a tangential route [1,2].”
BackgroundAlzu’bi, A., Lindsay, S., Kerwin, J. M., Looi, S. J., Khalil, F., & Clowry, G. J. (2016) · Brain Structure and Function · doi:10.1007/s00429-016-1343-5 · Cited by 54
“…and calcium-binding proteins (Bayatti et al. 2008a; Ip et al. 2010; Al-Jaberi et al. 2015) seemingly at odds with the accepted lateral (MGE derived) and posterior (CGE derived) pathways of migration for interneuron precursors from ventral to dorsal telencephalon (Wonders and Anderson 2006).”
BackgroundInfluentialPeyre, E., Silva, C. G., & Nguyen, L. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00129 · Cited by 51
“From their birthdates, the first interneurons populating the cortex are generated in the MGE and express PV, SST or CR/SST (Butt et al., 2005; Wonders and Anderson, 2006).”
BackgroundBecchetti, A., Gullo, F., Bruno, G., Dossi, E., Lecchi, M., & Wanke, E. (2012) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00063 · Cited by 51
Migratory pathways of GABAergic interneurons when they enter the neocortex
Tanaka, D. H., & Nakajima, K. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08111.x · Cited by 52
“%) progenitor cells are added together they would seem to account for the entire population of neocortical GABAergic interneurons; however, other subpallial sources, including the lateral ganglionic eminence (LGE), may account for a small proportion of them (Wonders & Anderson, 2006).”
BackgroundGeneration of diverse cortical inhibitory interneurons
Sultan, K. T., & Shi, S. (2017) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.306 · Cited by 57
Algamal, M., Russ, A. N., Miller, M. R., Hou, S. S., Maci, M., Munting, L. P., Zhao, Q., Gerashchenko, D., Bacskai, B. J., & Kastanenka, K. V. (2022) · Communications Biology · doi:10.1038/s42003-022-04268-x · Cited by 50
Cortical thinness and volume differences associated with marijuana abuse in emerging adults
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Synapse‐specific expression of calcium‐permeable AMPA receptors in neocortical layer 5
Lalanne, T., Oyrer, J., Mancino, A. S., Gregor, E., Chung, A. J., Huynh, L., Burwell, S., Maheux, J., Farrant, M., & Sjöström, P. J. (2015) · The Journal of Physiology · doi:10.1113/jp271394 · Cited by 49
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“A growing body of evidence suggests that diverse neurons are specified based on their precursor identity (Franco et al., 2012; Molyneaux et al., 2007; Wonders and Anderson, 2006).”
BackgroundSherwood, C. C., Raghanti, M. A., Stimpson, C. D., Spocter, M. A., Uddin, M., Boddy, A. M., Wildman, D. E., Bonar, C. J., Lewandowski, A. H., Phillips, K. A., et al. (2009) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2009.1831 · Cited by 52
“(e) Analysis of coding sequence evolution of interneuron-important genes among mammals Genes important to the transcriptional regulation of cortical interneuron specification and differentiation were identified from the literature (Wonders & Anderson 2006).”
Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility
Bae, M. H., Bissonette, G. B., Mars, W. M., Michalopoulos, G. K., Achim, C. L., Depireux, D. A., & Powell, E. M. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.10.011 · Cited by 50
“These neurons originate in the ventral telencephalon and migrate to populate the dorsal forebrain (Wonders and Anderson, 2006).”
Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice
Lee, F. H., Zai, C. C., Cordes, S. P., Roder, J. C., & Wong, A. H. (2013) · Molecular Brain · doi:10.1186/1756-6606-6-20 · Cited by 49
“Interneuron genesis in the ganglionic eminence is likely to be controlled by different transcription factors [40], but the relationship between DISC1 and interneuron production remains to be determined.”
BackgroundContribution of Long Noncoding RNAs to Autism Spectrum Disorder Risk
Wilkinson, B., & Campbell, D. B. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-418700-9.00002-2 · Cited by 49
Developmental mechanisms for the generation of telencephalic interneurons
Corbin, J. G., & Butt, S. J. B. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20890 · Cited by 58
Thumkeo, D., Shinohara, R., Watanabe, K., Takebayashi, H., Toyoda, Y., Tohyama, K., Ishizaki, T., Furuyashiki, T., & Narumiya, S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025465 · Cited by 50
“Consistently, as mice develop to adulthood, neurons positive with markers for both mature excitatory neurons (aCaMKII) [18,19] and inhibitory neurons (GABA) [20], as well as those for all major subtypes of interneuron (parvalbumin, somatostatin and calretinin) [21] were observed in the periventricular dysplastic mass…”
BackgroundDevelopmental Dynamics of Piriform Cortex
Sarma, A. A., Richard, M. B., & Greer, C. A. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhq199 · Cited by 49
“5) and migrate tangentially to their ultimate position in the neocortex (see (52, 53), for reviews).”
BackgroundThe reemergence of long-term potentiation in aged Alzheimer’s disease mouse model
Huh, S., Baek, S.-J., Lee, K., Whitcomb, D. J., Jo, J., Choi, S., Kim, D. H., Park, M., Lee, K. H., & Kim, B. C. (2016) · Scientific Reports · doi:10.1038/srep29152 · Cited by 53
Molecular Pathways Controlling the Sequential Steps of Cortical Projection Neuron Migration
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Modeling Psychiatric Disorder Biology with Stem Cells
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Role for TGF-β superfamily signaling in telencephalic GABAergic neuron development
Maira, M., Long, J. E., Lee, A. Y., Rubenstein, J. L. R., & Stifani, S. (2009) · Journal of Neurodevelopmental Disorders · doi:10.1007/s11689-009-9035-6 · Cited by 47
“…differentiate into projection neurons, or tangentially migrate to dorsal structures of the pallium such as the cortex, hippocampus and olfactory bulb, where they differentiate into different subclasses of interneurons (Marin and Rubenstein 2003; Wonders and Anderson 2006; Ayala et al. 2007].”
Zhang, Z., Wang, X., Park, S. S., Song, H., & Ming, G. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.12.015 · Cited by 49
Homeobox genes in vertebrate forebrain development and disease
Wigle, J. T., & Eisenstat, D. D. (2008) · Clinical Genetics · doi:10.1111/j.1399-0004.2008.00967.x · Cited by 50
“Diversity of cortical interneuron subtypes is established by coexpression of molecules such as parvalbumin (50%), somatostatin (30%), neuropeptide Y and calretinin (15%) with corresponding differences in their intrinsic physiological properties (12).”
BackgroundGomes, T. M., da Silva, D. D., Carmo, H., Carvalho, F. D., & Silva, J. P. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105237 · Cited by 49
Transcriptional Regulation of Cortical Interneuron Development: Figure 1.
Butt, S. J. B., Cobos, I., Golden, J. A., Kessaris, N., Pachnis, V., & Anderson, S. A. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3525-07.2007 · Cited by 47
“…from many laboratories have shown that cortical interneurons in rodents are born in subcortical regions and migrate tangentially over long distances to populate the cortex and the hippocampus (for recent review, see Marin and Rubenstein, 2003; Metin et al., 2006; Wonders and Anderson, 2006).”
Self-citationNew Pool of Cortical Interneuron Precursors in the Early Postnatal Dorsal White Matter
Riccio, O., Murthy, S. S., Szabó, G., Vutskits, L., Kiss, J. Z., Vitalis, T., Lebrand, C., & Dayer, A. G. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr086 · Cited by 46
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Krefft, O., Jabali, A., Iefremova, V., Koch, P., & Ladewig, J. (2018) · Journal of Visualized Experiments · doi:10.3791/56768 · Cited by 53
Accelerated Hyper-Maturation of Parvalbumin Circuits in the Absence of MeCP2
Patrizi, A., Awad, P. N., Chattopadhyaya, B., Li, C., Di Cristo, G., & Fagiolini, M. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhz085 · Cited by 46
Katsuki, F., Gerashchenko, D., & Brown, R. E. (2022) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2022.07.002 · Cited by 50
Neocortical neuron types in Xenarthra and Afrotheria: implications for brain evolution in mammals
Sherwood, C. C., Stimpson, C. D., Butti, C., Bonar, C. J., Newton, A. L., Allman, J. M., & Hof, P. R. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0198-9 · Cited by 45
“This range of phenotypic divergence of the interneuron system may be due to a number of factors, including Darwinian selection on genes important to the transcriptional regulation of interneuron specification and differentiation (Anderson et al. 1999; Wonders and Anderson 2006).”
BackgroundAligny, C., Roux, C., Dourmap, N., Ramdani, Y., do-Rego, J.-C., Jégou, S., Leroux, P., Leroux‐Nicollet, I., Marret, S., & Gonzalez, B. J. (2014) · Cell Death and Disease · doi:10.1038/cddis.2014.275 · Cited by 49
“advantage of the characterization of specific transcription factor expression profiles throughout the migration and differentiation of cortical interneurons arising from the MGE.(20) Ketamine induced a significant decrease in the protein levels of Nkx2.”
BackgroundThe Protocadherin Gene Celsr3 Is Required for Interneuron Migration in the Mouse Forebrain
Ying, G., Wu, S., Hou, R., Huang, W. M., Capecchi, M. R., & Wu, Q. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00011-09 · Cited by 46
“The acquisition of cortical interneuron subtypes is a long, mostly postnatal, developmental process (58).”
BackgroundInfluentialApplication of Fused Organoid Models to Study Human Brain Development and Neural Disorders
Chen, A., Guo, Z., Fang, L., & Bian, S. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00133 · Cited by 45
Tomassy, G. S., Morello, N., Calcagno, E., & Giustetto, M. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12803 · Cited by 49
Parvalbumin fast‐spiking interneurons are selectively altered by paediatric traumatic brain injury
Nichols, J., Bjorklund, G. R., Newbern, J. M., & Anderson, T. R. (2018) · The Journal of Physiology · doi:10.1113/jp275393 · Cited by 40
“The Journal of Physiology C© 2018 The Physiological Society paraformaldehyde/PBS essentially as described previously (Xing et al. 2016).”
MethodEx vivo fetal brain MRI: Recent advances, challenges, and future directions
Vasung, L., Charvet, C. J., Shiohama, T., Gagoski, B. A., Levman, J. E. D., & Takahashi, E. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.03.034 · Cited by 43
Yang, Z. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21557 · Cited by 44
“Actually, most cortical interneurons, possibly all of those in nonprimate mammals (rodent, ferret, and chicken), originate in the subcortical telencephalon and then migrate tangentially to the developing cortex (Wonders and Anderson, 2006).”
BackgroundGenetic mapping of ASIC 4 and contrasting phenotype to ASIC 1a in modulating innate fear and anxiety
Lin, S.-H., Chien, Y., Chiang, W.-W., Liu, Y., Lien, C., & Chen, C. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.12905 · Cited by 44
“Therefore, we used neurochemical markers such as Pv, SST, CB, CR, VIP and NPY to identify the major classes of cortical interneurons (Wonders & Anderson, 2006).”
MethodAn ontological approach to describing neurons and their relationships
Hamilton, D. J., Shepherd, G. M., Martone, M. E., & Ascoli, G. A. (2012) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2012.00015 · Cited by 42
“A way to deal with the cellular complexity of the nervous system is to group neurons into types based on their properties.”
BackgroundCOUP-TFII Expressing Interneurons in Human Fetal Forebrain
Reinchisi, G., Ijichi, K., Glidden, N. C., Jakovčevski, I., & Zečević, N. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr359 · Cited by 45
The Rac3 GTPase in Neuronal Development, Neurodevelopmental Disorders, and Cancer
de Curtis, I. (2019) · Cells · doi:10.3390/cells8091063 · Cited by 44
“The majority of cortical and hippocampal γ-aminobutyric acid (GABA)ergic interneurons are born in the medial and caudal ganglionic eminences located in the ventral telencephalon [37].”
BackgroundScala, M., Nishikawa, M., Nagata, K., & Striano, P. (2021) · Cells · doi:10.3390/cells10123395 · Cited by 43
Medina, L. M., & Abellán, A. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-369497-3.10007-x · Cited by 43
Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells
Goulburn, A. L., Stanley, E. G., Elefanty, A. G., & Anderson, S. A. (2011) · Stem Cell Research · doi:10.1016/j.scr.2011.12.002 · Cited by 44
“1) (Hebert and Fishell, 2008; Marin and Rubenstein, 2001; Nat and Dechant, 2011; Wonders and Anderson, 2006).”
Self-citationAttenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1
Hayashi, A., Kasahara, T., Kametani, M., & Kato, T. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.09.059 · Cited by 42
Real, M. A., Heredia, R., Labrador, M. D. C., Dávila, J. C., & Guirado, S. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.21970 · Cited by 42
Sensory coding is impaired in rat absence epilepsy
Studer, F., Laghouati, E., Jarre, G., Olivier David, A., Pouyatos, B., & Depaulis, A. (2018) · The Journal of Physiology · doi:10.1113/jp277297 · Cited by 42
The Polarised Life of the Endocannabinoid System in CNS Development
Anavi‐Goffer, S., & Mulder, J. (2009) · ChemBioChem · doi:10.1002/cbic.200800827 · Cited by 45
Westerholz, S., de Lima, A. D., & Voigt, T. B. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.03.039 · Cited by 41
Mechanisms of Long Non-Coding RNAs in the Assembly and Plasticity of Neural Circuitry
Wang, A., Wang, J., Liu, Y., & Zhou, Y. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00076 · Cited by 42
“In contrast, cortical interneurons, which usually make local and inhibitory connections, are produced mostly from precursors in the ventral telencephalon and cortical hem and undergo tangential migration into the cortex (Anderson et al., 2002; Wonders and Anderson, 2006).”
BackgroundMcKenzie, M. G., Cobbs, L., Dummer, P. D., Petros, T. J., Halford, M. M., Stacker, S. A., Zou, Y., Fishell, G., & Au, E. (2019) · Neuron · doi:10.1016/j.neuron.2019.06.003 · Cited by 42
“Furthermore, intrinsic regulation of interneuron identity by transcriptional regulation has been extensively studied (Wonders and Anderson, 2006).”
BackgroundOrigin, Development, and Synaptogenesis of Cortical Interneurons
Llorca, A., & Deogracias, R. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.929469 · Cited by 46
“These structures are responsible for the generation of two major IN classes: PV and SST cells (Lavdas et al., 1999; Wonders and Anderson, 2006; Xu et al., 2008; Gelman et al., 2009, 2011; Marín, 2013), as well as long-range projecting nNOS+ neurons (Magno et al.”
BackgroundGeneration of diverse neuronal subtypes in cloned populations of stem-like cells
Varga, B. V., Hádinger, N., Gócza, E., Dulberg, V., Demeter, K., Madarász, E., & Herberth, B. (2008) · BMC Developmental Biology · doi:10.1186/1471-213x-8-89 · Cited by 43
“The gene cascade is required for the differentiation and migration of ventral forebrain derived GABAergic interneurons of the cortex [12,11,13].”
BackgroundAbe, P., Molnár, Z., Tzeng, Y.-S., Lai, D., Arnold, S. J., & Stumm, R. K. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.1488-15.2015 · Cited by 40
“They migrate preferentially on characteristic routes including the cortical subventricular zone (SVZ) and marginal zone (MZ) (Wonders and Anderson, 2006).”
BackgroundCortical neurogenesis from pluripotent stem cells: complexity emerging from simplicity
Anderson, S., & Vanderhaeghen, P. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.03.012 · Cited by 40
“The telencephalon then undergoes patterning along the dorso-ventral axis, leading to the parcellation into several neurogenic niches, including the dorsal telencephalon and the ventrally located ganglionic eminences, which will generate cortical pyramidal neurons and most interneurons, respectively [6,7,8].”
Self-citationZhong, J., Kim, H.-T., Lyu, J., Yoshikawa, K., Nakafuku, M., & Lu, W. (2011) · Development · doi:10.1242/dev.061051 · Cited by 43
“GABAergic neurons originate from the subpallium, including the medial ganglionic eminence (MGE), the lateral ganglionic eminence (LGE) and the anterior entopeduncular area (AEP) (Wonders and Anderson, 2006).”
BackgroundInfluentialEndoh‐Yamagami, S., Karkar, K. M., May, S., Cobos, I., Thwin, M. T., Long, J. E., Ashique, A. M., Zarbalis, K. S., Rubenstein, J. L. R., & Peterson, A. S. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.01.017 · Cited by 41
“On the other hand, interneurons are born in the subpallium, the ventral region of the telencephalon, and they migrate tangentially into the cortex or olfactory bulb (Ayala et al., 2007; Marín and Rubenstein, 2003; Wonders and Anderson, 2006).”
BackgroundElongator controls cortical interneuron migration by regulating actomyosin dynamics
Tielens, S., Huysseune, S., Godin, J. D., Chariot, A., Malgrange, B., & Nguyen, L. (2016) · Cell Research · doi:10.1038/cr.2016.112 · Cited by 40
Linking neuronal lineage and wiring specificity
Li, H., Shuster, S. A., Li, J., & Luo, L. (2018) · Neural Development · doi:10.1186/s13064-018-0102-0 · Cited by 40
“Cortical interneurons, however, develop from distinct lineages originating in the medial ganglionic eminence, caudal ganglionic eminence and preoptic area [93, 94].”
BackgroundSymmank, J., Bayer, C., Schmidt, C., Hahn, A., Pensold, D., & Zimmer‐Bensch, G. (2018) · Epigenetics · doi:10.1080/15592294.2018.1475980 · Cited by 41
Metadata
- Authors
- Wonders, C. P., & Anderson, S. A.
- Affiliations
- Cornell University (US)
- Corresponding author
- Anderson, Stewart A.
- ORCID
- Anderson, Stewart A.
- Venue
- Nature Reviews Neuroscience
- Published
- 2006-08-02
- Volume
- 7
- Issue
- 9
- Pages
- 687-696
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W2007034511
- Cited by
- 980
- References
- 142
- Citations by year
- 2026: 32 · 2025: 49 · 2024: 39 · 2023: 47 · 2022: 32 · 2021: 42 · 2020: 66 · 2019: 53 · 2018: 43 · 2017: 52 · 2016: 49 · 2015: 49 · 2014: 53 · 2013: 54 · 2012: 50
- FWCI
- 3.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- cortical interneurons, interneuron specification, GABAergic neurons, cortical development, transcriptional regulation, interneuron subtypes, neuronal maturation
- MeSH terms
- Animals, Cell Differentiation, Cell Movement, Cerebral Cortex, Humans, Interneurons, Nerve Tissue Proteins, Stem Cells, Telencephalon, Biomarkers, Gene Expression Regulation, Developmental, Cell Lineage
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