Retinoic acid in the development, regeneration and maintenance of the nervous system

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

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TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

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Gene expression regulation by retinoic acid

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Overview of retinoid metabolism and function

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A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A

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Nuclear retinoid receptors and the transcription of retinoid-target genes

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Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

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Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

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Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development

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Retinoid signalling in the development of the central nervous system

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Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures

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Motor Neuron–Derived Retinoid Signaling Specifies the Subtype Identity of Spinal Motor Neurons

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Vitamin A-deficient quail embryos have half a hindbrain and other neural defects.

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A Requirement for Retinoic Acid-Mediated Transcriptional Activation in Ventral Neural Patterning and Motor Neuron Specification

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Impaired Locomotion and Dopamine Signaling in Retinoid Receptor Mutant Mice

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Molecular Identification of a Major Retinoic‐Acid‐Synthesizing Enzyme, a Retinaldehyde‐Specific Dehydrogenase

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RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ developmentPreprint

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Assigning the Positional Identity of Spinal Motor Neurons

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An Essential Role for Retinoid Receptors RARβ and RXRγ In Long-Term Potentiation and Depression

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Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines

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The mechanisms of dorsoventral patterning in the vertebrate neural tube

Wilson, L. J., & Maden, M. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.02.027 · Cited by 316 · see citing works

Direct Channeling of Retinoic Acid between Cellular Retinoic Acid-Binding Protein II and Retinoic Acid Receptor Sensitizes Mammary Carcinoma Cells to Retinoic Acid-Induced Growth Arrest

Budhu, A. S., & Noy, N. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.8.2632-2641.2002 · Cited by 296 · see citing works

Opposing FGF and retinoid pathways: a signalling switch that controls differentiation and patterning onset in the extending vertebrate body axis

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Complementary Domains of Retinoic Acid Production and Degradation in the Early Chick Embryo

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High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system.

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Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity

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Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis

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Role of retinoids in the CNS: differential expression of retinoid binding proteins and receptors and evidence for presence of retinoic acid

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The concentration of retinoic acid determines the differentiated cell types formed by a teratocarcinoma cell line

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Plasma Delivery of Retinoic Acid to Tissues in the Rat

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An essential role for retinoid signaling in anteroposterior neural patterning

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Differential expression of retinoid receptors in the adult mouse central nervous system

Krężel, W., Kastner, P., & Chambon, P. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00342-x · Cited by 238 · see citing works

Vitamin A deficiency produces spatial learning and memory impairment in rats

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Regulation of dopaminergic pathways by retinoids: Activation of the D2 receptor promoter by members of the retinoic acid receptor–retinoid X receptor family

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The γ-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

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13- cis -retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice

Crandall, J. E., Sakai, Y., Zhang, J., Koul, O., Mineur, Y. S., Crusio, W. E., & McCaffery, P. J. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306336101 · Cited by 213 · see citing works

Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays

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Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome

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Quantification of endogenous retinoic acid in limited biological samples by LC/MS/MS

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The distribution of endogenous retinoic acid in the chick embryo: implications for developmental mechanisms

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Peripheral nerve regeneration by transplantation of bone marrow stromal cell—derived Schwann cells in adult rats

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Disruption of the retinoid signalling pathway causes a deposition of amyloid β in the adult rat brain

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Vitamin A deficiency and relational memory deficit in adult mice: relationships with changes in brain retinoid signalling

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The control of rostrocaudal pattern in the developing spinal cord: specification of motor neuron subtype identity is initiated by signals from paraxial mesoderm

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Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor

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Coordinated Up-regulation of Choline Acetyltransferase and Vesicular Acetylcholine Transporter Gene Expression by the Retinoic Acid Receptor α, cAMP, and Leukemia Inhibitory Factor/Ciliary Neurotrophic Factor Signaling Pathways in a Murine Septal Cell Line

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Retinoic acid signaling and function in the adult hippocampus

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A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the timing of neuronal differentiation in Xenopus neuroectoderm

Papalopulu, N., & Kintner, C. R. (1996) · Development · doi:10.1242/dev.122.11.3409 · Cited by 162 · see citing works

Role and distribution of retinoic acid during CNS development

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Cloned human teratoma cells differentiate into neuron-like cells and other cell types in retinoic acid

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Retinoic acid and hindbrain patterning

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Retinoid receptor signaling in postmitotic motor neurons regulates rostrocaudal positional identity and axonal projection pattern.

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Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth

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Retinoid receptors, transporters, and metabolizers as therapeutic targets in late onset Alzheimer disease

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The role of retinoic acid receptors in neurite outgrowth from different populations of embryonic mouse dorsal root ganglia

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Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain.

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Acylglycerol Recycling from Triacylglycerol to Phospholipid, Not Lipase Activity, Is Defective in Neutral Lipid Storage Disease Fibroblasts

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Retinoic acid signalling centres in the avian embryo identified by sites of expression of synthesising and catabolising enzymes

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Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro

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Genomic structure and functional characterization of the human ADAM10 promoter

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Working memory deficits in retinoid X receptor γ-deficient micePreprint

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Retinoic acid receptor β2 promotes functional regeneration of sensory axons in the spinal cord

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Retinoic Acid Synthesis in the Postnatal Mouse Brain Marks Distinct Developmental Stages and Functional Systems

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The Role of Vitamin A in the Development of the Central Nervous System ,

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Retinoic acid receptor β2 and neurite outgrowth in the adult mouse spinal cord in vitro

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Generating gradients of retinoic acid in the chick embryo: <i>Cyp26C1</i> expression and a comparative analysis of the Cyp26 enzymes

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Retinoic acid and the control of dorsoventral patterning in the avian spinal cord

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Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1

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Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and up-regulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebral ischemia

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Site-Specific Retinoic Acid Production in the Brain of Adult Songbirds

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Retinoic acid regulates postnatal neurogenesis in the murine subventricular zone-olfactory bulb pathway

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Regulation of Acetylcholinesterase Expression during Neuronal Differentiation

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Retinoic acid synthesis for the developing telencephalon.

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Induction of neural-like cells and acetylcholinesterase activity in cultures of F9 teratocarcinoma treated with retinoic acid and dibutyryl cyclic adenosine monophosphate

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Functional association of retinoic acid and hedgehog signaling in Xenopus primary neurogenesis

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Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons

Vermot, J., Schuhbaur, B., Mouellic, H. L., McCaffery, P., Garnier, J., Hentsch, D., Brûlet, P., Niederreither, K., Chambon, P., Dollé, P., et al. (2005) · Development · doi:10.1242/dev.01718 · Cited by 86 · see citing works

Retinoic acid is detected at relatively high levels in the CNS of adult rats

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Lentiviral vector expressing retinoic acid receptor β2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord

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New therapeutic target for CNS injury? The role of retinoic acid signaling after nerve lesions

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Retinoic acid signaling at sites of plasticity in the mature central nervous system

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Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease.

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Expression of the Wnt inhibitor Dickkopf‐1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid

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Age-related decreases in mRNA for brain nuclear receptors and target genes are reversed by retinoic acid treatment

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Retinoid receptors promote primary neurogenesis in Xenopus

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Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats

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Transplantation of neural cells derived from retinoic acid-treated cynomolgus monkey embryonic stem cells successfully improved motor function of hemiplegic mice with experimental brain injury

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Lesions of basal ganglia due to disulfiram neurotoxicity.

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Absence of retinoids can induce motoneuron disease in the adult rat and a retinoid defect is present in motoneuron disease patients

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Defined concentrations of a posteriorizing signal are critical for MafB/Kreisler segmental expression in the hindbrain

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Retinoic acid normalizes nuclear receptor mediated hypo-expression of proteins involved in β-amyloid deposits in the cerebral cortex of vitamin A deprived rats

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Retinoic acid signaling in the brain marks formation of optic projections, maturation of the dorsal telencephalon, and function of limbic sites

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Activation of retinoic acid signalling after sciatic nerve injury: up‐regulation of cellular retinoid binding proteins

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