History and progress of hypotheses and clinical trials for Alzheimer’s disease

Imaging amyloid deposition in Lewy body diseases

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Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

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Post-translational modifications of tau protein in Alzheimer’s disease

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Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease

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A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis

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Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

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Expression of the histocompatibility glycoprotein HLA-DR in neurological disease

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Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

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Anti‐inflammatory agents as a therapeutic approach to Alzheimer's disease

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Formation of β-amyloid protein deposits in brains of transgenic mice

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THE FINE STRUCTURE OF NEUROFIBRILLARY TANGLES IN ALZHEIMERʼS DISEASE

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Neuron-Specific Apolipoprotein E4 Proteolysis Is Associated with Increased Tau Phosphorylation in Brains of Transgenic Mice

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Elevated risk of type 2 diabetes for development of Alzheimer disease: A key role for oxidative stress in brain

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Epigenetic changes in Alzheimer's disease: Decrements in DNA methylation

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SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

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APOE -ε4 count predicts age when prevalence of AD increases, then declines: The Cache County Study

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Balance and Stability of Synaptic Structures during Synaptic Plasticity

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Cell biology of the mitochondrion

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A CLICKING HIP IN A NEWBORN BABY SHOULD NEVER BE IGNORED

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Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of Aβ42 and Aβ40 peptides by γ-secretase

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Genetics of healthy aging and longevity

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Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans

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Is There a Cerebral Lymphatic System?

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Mitochondria and Epigenetics – Crosstalk in Homeostasis and Stress

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Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia

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Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease

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Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

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Neuropathology of Alzheimer’s disease: what is new since A. Alzheimer?

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Alzheimer's disease, metal ions and metal homeostatic therapy

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Hippocampal volume in primary unipolar major depression: a magnetic resonance imaging study

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Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model

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Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

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Neurodegenerative lysosomal disorders: A continuum from development to late age

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Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study

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Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial

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Three-dimensional structure of human γ-secretase

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Neuroinflammation in Alzheimer's Disease and Mild Cognitive Impairment: A Field in Its Infancy

McGeer, E. G., & McGeer, P. L. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1219 · Cited by 353

Sex differences in Alzheimer's disease and other dementias

Mazure, C. M., & Swendsen, J. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(16)00067-3 · Cited by 350

Fibrillar β-Amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat CNS In Vivo

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Fluorescence imaging of metal ions implicated in diseases

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Abnormalities of mitochondrial enzymes in Alzheimer disease

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Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

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Iron misregulation in the brain: a primary cause of neurodegenerative disorders

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One of the Antigenic Determinants of Paired Helical Filaments Is Related to Tau Protein1

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Medicinal Inorganic Chemistry Approaches to Passivation and Removal of Aberrant Metal Ions in Disease

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Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders

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Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice

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Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

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Regulation of ATP production by mitochondrial Ca2+

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Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer

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Passive immunization targeting pathological phospho‐tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

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Lithium, a Common Drug for Bipolar Disorder Treatment, Regulates Amyloid-β Precursor Protein Processing

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Epigenetic Differences in Cortical Neurons from a Pair of Monozygotic Twins Discordant for Alzheimer's Disease

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Widespread age-related differences in the human brain microstructure revealed by quantitative magnetic resonance imaging

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Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond

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Human and Murine ApoE Markedly Alters Aβ Metabolism before and after Plaque Formation in a Mouse Model of Alzheimer's Disease

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Translation of the Alzheimer Amyloid Precursor Protein mRNA Is Up-regulated by Interleukin-1 through 5′-Untranslated Region Sequences

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Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications

Liu, J., Fan, Y., Yang, Z., Wang, Z., & Guo, C. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00632 · Cited by 289

Presenilin-dependent Intramembrane Proteolysis of CD44 Leads to the Liberation of Its Intracellular Domain and the Secretion of an Aβ-like Peptide

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Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics

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ALZHEIMERʼS DISEASE

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Iron and Alzheimer’s Disease: An Update on Emerging Mechanisms

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Insulin Resistance and Alzheimer’s Disease: Bioenergetic Linkages

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Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?

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Changes in Brain Volume and Cognition in a Randomized Trial of Exercise and Social Interaction in a Community-Based Sample of Non-Demented Chinese Elders

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Role of inflammatory molecules in the Alzheimer's disease progression and diagnosis

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Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

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Tau Is Enriched on Dynamic Microtubules in the Distal Region of Growing Axons

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The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice

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Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing

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The role of metallobiology and amyloid-β peptides in Alzheimer's disease

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Proteolytic Processing of Low Density Lipoprotein Receptor-related Protein Mediates Regulated Release of Its Intracellular Domain

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A cross-sectional comparison of brain glucose and ketone metabolism in cognitively healthy older adults, mild cognitive impairment, and early Alzheimer’s disease

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Presenilin-1 mutations and Alzheimer’s disease.

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Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease

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Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine

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Tau Binds to the Distal Axon Early in Development of Polarity in a Microtubule- and Microfilament-Dependent Manner

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Aβ1–40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation

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Genetics of Alzheimer's Disease: A Centennial Review

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Short‐term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus

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PINK1-induced mitophagy promotes neuroprotection in Huntington’s disease

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Expression of iron transport proteins and excessive iron accumulation in the brain in neurodegenerative disorders

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Calcineurin Triggers Reactive/Inflammatory Processes in Astrocytes and Is Upregulated in Aging and Alzheimer's Models

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Role of Iron in Neurodegenerative Disorders

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Rivastigmine and donepezil treatment in moderate to moderately-severe Alzheimer's disease over a 2-year period

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Drowning stars: reassessing the role of astrocytes in brain edema

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FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure

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Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease

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The Metabolism of Tyramine by Monoamine Oxidase A/B Causes Oxidative Damage to Mitochondrial DNA

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