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Evidence for a large-scale brain system supporting allostasis and interoception in humans
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Abstract
Large-scale intrinsic brain systems have been identified for exteroceptive senses (such as sight, hearing and touch). We introduce an analogous system for representing sensations from within the body, called interoception, and demonstrate its relation to regulating peripheral systems in the body, called allostasis. Employing the recently introduced Embodied Predictive Interoception Coding (EPIC) model, we used tract-tracing studies of macaque monkeys, followed by two intrinsic functional magnetic resonance imaging samples (N = 280 and N = 270) to evaluate the existence of an intrinsic allostatic–interoceptive system in the human brain. Another sample (N = 41) allowed us to evaluate the convergent validity of the hypothesized allostatic–interoceptive system by showing that individuals with stronger connectivity between system hubs performed better on an implicit index of interoceptive ability related to autonomic fluctuations. Implications include insights for the brain’s functional architecture, dissolving the artificial boundary between mind and body, and unifying mental and physical illness.
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“Within the brain, different interoceptive channels share common regional neural substrates that likely permit integrative processing towards (predictive) representations that might ultimately direct adaptive behaviour [10].”
From Interoception and emotion. (2017) · cites this paper as [10]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Each network is comprised of cortical and subcortical regions interconnected by the brain’s hub regions, including but not limited to regions important for motivation such as the anterior subregion of the mid-cingulate cortex (aMCC) (Kleckner et al., 2017).”
From Motivation in the Service of Allostasis: The Role of Anterior Mid-Cingulate Cortex (2019) · cites this paper as Kleckner et al., 2017
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“Recent neuroscience research points to a large-scale system in the brain supporting allostasis, which connects predictions about energy requirements to systems that monitor and regulate the state of the body (Kleckner et al., 2017).”
From Motivation in the Service of Allostasis: The Role of Anterior Mid-Cingulate Cortex (2019) · cites this paper as Kleckner et al., 2017
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“Evidence from brain connectivity studies show that the aMCC participates in systems associated with visceromotor functions such as the “salience” (Seeley et al., 2007; Touroutoglou et al., 2012) and “allostatic-interoceptive” networks (Kleckner et al., 2017) as well as networks associated with executive function, attention, and motor control such as “frontoparietal control” (Vincent et al., 2008),”
From Motivation in the Service of Allostasis: The Role of Anterior Mid-Cingulate Cortex (2019) · cites this paper as Kleckner et al., 2017
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“This system includes two of the brain’s major intrinsic networks involved in sensing, thinking, and feeling (known as the salience and default mode network) (see Figure 1; (Kleckner et al., 2017).”
From Motivation in the Service of Allostasis: The Role of Anterior Mid-Cingulate Cortex (2019) · cites this paper as Kleckner et al., 2017
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In the citing paper
“Interoception seemingly involves a high degree of connectivity within the brain (135).”
From Interoception and Mental Health: A Roadmap. (2018) · cites this paper as [135]
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“Beyond allostasis, the predictive coding framework proposes that estimating the most likely cause of changes in internal bodily parameters, given a certain exteroceptive context, gives rise to emotional feelings 209-211 , with a particular role for anterior cingulate and anterior insular cortices to generate visceral predictions 212 .”
From Interoceptive rhythms in the brain (2023) · cites this paper as [212]
In the citing paper
“Interoception impairment (i.e., difficulties in the sensing, perceiving, and anticipating of signals arising from within the body) is a core feature that can occur in multiple clinical conditions.1, 2, 3”
From Altered spatiotemporal brain dynamics of interoception in behavioural-variant frontotemporal dementia (2025) · cites this paper as [3]
In the citing paper
“Allostatic-interoception is underpinned by the Allostatic-Interoceptive Network (AIN), a large-scale domain-general network including the anterior cingulate cortex, insula, orbitofrontal cortex, amygdala, thalamus, hippocampus, ventral striatum, and angular gyrus.1,3,14”
From Altered spatiotemporal brain dynamics of interoception in behavioural-variant frontotemporal dementia (2025) · cites this paper as [3]
In the citing paper
“Allostasis (i.e., the brain's continual prediction, anticipation, and adaptation to meet the body's needs before they arise or become urgent)13 is deeply intertwined with interoception.3”
From Altered spatiotemporal brain dynamics of interoception in behavioural-variant frontotemporal dementia (2025) · cites this paper as [3]
In the citing paper
“Moreover, both atrophy and functional connectivity alterations observed in people with bvFTD14,17,24 substantially overlap with the AIN.3”
From Altered spatiotemporal brain dynamics of interoception in behavioural-variant frontotemporal dementia (2025) · cites this paper as [3]
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Citations
Cites
James, W. (1891) · Personality Culture Society · doi:10.1037/11059-000 · Cited by 25,876
Control of goal-directed and stimulus-driven attention in the brain
Corbetta, M., & Shulman, G. L. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn755 · Cited by 12,881
(1994) · DigitalGeorgetown (Georgetown University Library) · Cited by 10,542
Measuring emotion: The self-assessment manikin and the semantic differential
Bradley, M. M., & Lang, P. J. (1994) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(94)90063-9 · Cited by 9,538
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
Thomas Yeo, B. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zöllei, L., Polimeni, J. R., et al. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00338.2011 · Cited by 9,182
DESCARTES' ERROR: Emotion, Reason, and the Human Brain
Marg, E. (1995) · Optometry and Vision Science · doi:10.1002/j.1538-9235.1995.tb03988.x · Cited by 8,178
The free-energy principle: a unified brain theory?
Friston, K. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2787 · Cited by 8,120 · cited 1×
“Predictions guide action and perception by continually constructing possible representations of the immediate future based on their prior probabilities relative to the present context 8,9 .”
Fodor, J. A. (1983) · doi:10.7551/mitpress/4737.001.0001 · Cited by 7,734
Power, J. D., Barnes, K. A., Snyder, A. Z., Schlaggar, B. L., & Petersen, S. E. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.10.018 · Cited by 7,429
Dissociable intrinsic connectivity networks for salience processing and executive control
Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5587-06.2007 · Cited by 7,426
Research works printed but not linked: 2
- Sherrington, C. in Textbook of Physiology (ed. Schäfer, E. A. ) 920–1001 (Pentland, 1900).
- Clark-Polner, E., Wager, T. D., Satpute, A. B. & Barrett, L. F. in The Handbook of Emotion (eds Barrett, L. F., Lewis, M. & Haviland-Jones, J. M. ) 146–165 (Guilford Press, 2016).
Cited by
Sorted by citations
Interoception and Mental Health: A Roadmap.
Khalsa, S. S., Adolphs, R., Cameron, O. G., Critchley, H. D., Davenport, P. W., Feinstein, J. S., Feusner, J. D., Garfinkel, S. N., Lane, R. D., Mehling, W. E., et al. (2018) · Biological psychiatry. Cognitive neuroscience and neuroimaging · doi:10.1016/j.bpsc.2017.12.004 · Cited by 1,453
Self-citationThe theory of constructed emotion: an active inference account of interoception and categorization
Barrett, L. F. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw154 · Cited by 1,426
Self-citationThe theory of constructed emotion: an active inference account of interoception and categorization
Barrett, L. F. (2017) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsx060 · Cited by 1,009
Self-citationCritchley, H. D., & Garfinkel, S. N. (2017) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2017.04.020 · Cited by 899
“Within the brain, different interoceptive channels share common regional neural substrates that likely permit integrative processing towards (predictive) representations that might ultimately direct adaptive behaviour [10].”
BackgroundChen, W. G., Schloesser, D., Arensdorf, A. M., Simmons, J. M., Cui, C., Valentino, R., Gnadt, J. W., Nielsen, L., Hillaire-Clarke, C. S., Spruance, V., et al. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2020.10.007 · Cited by 707
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Barrett, L. F., Quigley, K. S., & Hamilton, P. (2016) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2016.0011 · Cited by 554
Self-citationConnecting minds and sharing emotions through mimicry: A neurocognitive model of emotional contagion
Prochazkova, E., & Kret, M. E. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.05.013 · Cited by 433
“In support of NMEC, researchers began to identify analogous introspective mechanisms for representing sensations from within the body (Kleckner et al., 2017).”
InfluentialVisceral Signals Shape Brain Dynamics and Cognition
Azzalini, D., Rebollo, I., & Tallon-Baudry, C. (2019) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2019.03.007 · Cited by 409
Atzil, S., Gao, W., Fradkin, I., & Barrett, L. F. (2018) · Nature Human Behaviour · doi:10.1038/s41562-018-0384-6 · Cited by 415
Ashar, Y. K., Gordon, A., Schubiner, H., Uipi, C., Knight, K., Anderson, Z., Carlisle, J., Polisky, L., Geuter, S., Flood, T. F., et al. (2022) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2021.2669 · Cited by 331
“Unemployed/lightly employed (<5 h/wk) 7 (14) 13 (25) 9 (18) Subjective socioeconomic status, mean (SD), 1-1060 6.”
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Quigley, K. S., Kanoski, S., Grill, W. M., Barrett, L. F., & Tsakiris, M. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2020.09.008 · Cited by 286
Self-citationThe power of predictions: An emerging paradigm for psychological research
Hutchinson, J. B., & Barrett, L. F. (2019) · Current Directions in Psychological Science · doi:10.1177/0963721419831992 · Cited by 216
Pace-Schott, E. F., Amole, M. C., Aue, T., Balconi, M., Bylsma, L. M., Critchley, H., Demaree, H. A., Friedman, B. H., Gooding, A. E. K., Gosseries, O., et al. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.05.002 · Cited by 221
“Following influential reviews (Cameron, 2001; Craig, 2002, 2016; Critchley, 2005), the study of interoception in relation to normal emotion has blossomed (Barrett, 2017c; Craig, 2010; Critchley and Garfinkel, 2017; Kleckner et al., 2017; Krautwurst et al., 2016; Strigo and Craig, 2016).”
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Engelen, T., Solcà, M., & Tallon-Baudry, C. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01425-1 · Cited by 207
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Wang, X., Wu, Q., Egan, L., Gu, X., Liu, P., Gu, H., Yang, Y., Luo, J., Wu, Y., Gao, Z., et al. (2019) · eLife · doi:10.7554/elife.42265 · Cited by 204
The sense of should: A biologically-based framework for modeling social pressure
Theriault, J. E., Young, L., & Barrett, L. F. (2021) · Physics of Life Reviews · doi:10.1016/j.plrev.2020.01.004 · Cited by 201
Self-citationHistorical pitfalls and new directions in the neuroscience of emotion
Barrett, L. F., & Satpute, A. B. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2017.07.045 · Cited by 180
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Critchley, H. D., & Garfinkel, S. N. (2018) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2017.08.014 · Cited by 178
Kraynak, T. E., Marsland, A. L., Wager, T. D., & Gianaros, P. J. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.07.013 · Cited by 165
Interoception primes emotional processing: multimodal evidence from neurodegeneration
Salamone, P. C., Legaz, A., Sedeño, L., Moguilner, S., Fraile-Vazquez, M., Campo, C. G., Fittipaldi, S., Yoris, A., Miranda, M., Birba, A., et al. (2021) · The Journal of Neuroscience · doi:10.1523/jneurosci.2578-20.2021 · Cited by 103
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Sennesh, E., Theriault, J., Brooks, D., van de Meent, J.-W., Barrett, L. F., & Quigley, K. S. (2022) · Biological Psychology · doi:10.1016/j.biopsycho.2021.108242 · Cited by 107
Self-citationConcepts, goals and the control of survival-related behaviors
Feldman Barrett, L., & Finlay, B. L. (2018) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2018.10.001 · Cited by 89
Self-citationAllostasis, action and affect in depression: Insights from the theory of constructed emotion
Shaffer, C., Westlin, C., Quigley, K. S., Whitfield-Gabrieli, S., & Barrett, L. F. (2022) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-081219-115627 · Cited by 94
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Al, E., Iliopoulos, F., Nikulin, V. V., & Villringer, A. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118247 · Cited by 86
Allostasis as a core feature of hierarchical gradients in the human brain
Katsumi, Y., Theriault, J. E., Quigley, K. S., & Barrett, L. F. (2022) · Network Neuroscience · doi:10.1162/netn_a_00240 · Cited by 88
Self-citationAinley, V., Tsakiris, M., Pollatos, O., Schulz, A., & Herbert, B. M. (2020) · Biological Psychology · doi:10.1016/j.biopsycho.2020.107870 · Cited by 88
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Bogdanova, O. V., Bogdanov, V. B., Dureux, A., Farnè, A., & Hadj-Bouziane, F. (2021) · Cortex · doi:10.1016/j.cortex.2021.05.005 · Cited by 86
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BackgroundA predictive coding framework of allostatic–interoceptive overload in frontotemporal dementia
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Arnaldo, I., Corcoran, A. W., Friston, K. J., & Ramstead, M. J. D. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104590 · Cited by 56
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Zhang, J., Abiose, O., Katsumi, Y., Touroutoglou, A., Dickerson, B. C., & Barrett, L. F. (2019) · Scientific Reports · doi:10.1038/s41598-019-51793-7 · Cited by 47
Self-citationKozlowska, K., Spooner, C. J., Palmer, D. M., Harris, A., Korgaonkar, M. S., Scher, S., & Williams, L. M. (2018) · NeuroImage: Clinical · doi:10.1016/j.nicl.2018.02.003 · Cited by 47
Reis, J. C., Antoni, M. H., & Travado, L. (2020) · CNS Spectrums · doi:10.1017/s1092852918001621 · Cited by 44
Sojka, P., Diez, I., Bareš, M., & Perez, D. L. (2021) · Human Brain Mapping · doi:10.1002/hbm.25304 · Cited by 43
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Gerrans, P. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.523710 · Cited by 43
Hoemann, K., Khan, Z., Kamona, N., Dy, J., Barrett, L. F., & Quigley, K. S. (2021) · Psychophysiology · doi:10.1111/psyp.13818 · Cited by 40
Self-citationAbrevaya, S., Fittipaldi, S., García, A. M., Dottori, M., Santamaria-Garcia, H., Birba, A., Yoris, A., Hildebrandt, M. K., Salamone, P., De la Fuente, A., et al. (2020) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000868 · Cited by 34
Rai, S., Foster, S., Griffiths, K. R., Breukelaar, I. A., Kozlowska, K., & Korgaonkar, M. S. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103110 · Cited by 35
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Ibanez, A., & Northoff, G. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105510 · Cited by 36
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Touroutoglou, A., Andreano, J. M., Adebayo, M., Lyons, S., & Barrett, L. F. (2019) · Advances in Motivation Science · doi:10.1016/bs.adms.2018.09.002 · Cited by 25
“, 2012) and “allostatic-interoceptive” networks (Kleckner et al., 2017) as well as networks associated with executive function, attention, and motor control such as “frontoparietal control” (Vincent et al.”
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Bury, G., García-Huéscar, M., Bhattacharya, J., & Ruiz, M. H. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.04.043 · Cited by 20
Price, C. J., Sevinc, G., & Farb, N. A. S. (2023) · Brain Sciences · doi:10.3390/brainsci13101396 · Cited by 20
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Katsumi, Y., Kamona, N., Zhang, J., Bunce, J. G., Hutchinson, J. B., Yarossi, M., Tunik, E., Quigley, K. S., Dickerson, B. C., & Barrett, L. F. (2021) · doi:10.1101/2021.09.01.456844 · Cited by 89
Self-citationGendron, M., Mesquita, B., & Barrett, L. F. (2020) · Culture, Mind, and Brain · doi:10.1017/9781108695374.010 · Cited by 20
Young, R. A., Martin, C. M., Sturmberg, J. P., Hall, S., Bazemore, A., Kakadiaris, I. A., & Lin, S. (2024) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2023.230219r1 · Cited by 17
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Kozlowska, K., Schollar-Root, O., Savage, B., Hawkes, C., Chudleigh, C., Raghunandan, J., Scher, S., & Helgeland, H. (2023) · Children · doi:10.3390/children10111724 · Cited by 14
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BackgroundHazelton, J. L., Della Bella, G., Barttfeld, P., Dottori, M., Gonzalez-Gomez, R., Migeot, J., Moguilner, S., Legaz, A., Hernandez, H., Prado, P., et al. (2025) · eBioMedicine · doi:10.1016/j.ebiom.2025.105614 · Cited by 14
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Theriault (n.d.) · doi:10.31234/osf.io/pkzr8 · Cited by 51
Metadata
- Authors
- Kleckner, I. R., Zhang, J., Touroutoglou, A., Chanes, L., Xia, C., Simmons, W. K., Quigley, K. S., Dickerson, B. C., & Feldman Barrett, L.
- Affiliations
- Northeastern University (US)
- Harvard University (US)
- Laureate Institute for Brain Research (US)
- Corresponding author
- Kleckner, Ian R.
- ORCID
- Venue
- Nature Human Behaviour
- Published
- 2017-04-24
- Volume
- 1
- Issue
- 5
- ISSN
- 2397-3374 (ISSN-L)
- PMC
- PMC5624222
- OpenAlex
- W2949653992
- Semantic Scholar
- 79ae92da636496383feb502c600494d896c27829
- Cited by
- 641
- References
- 248
- Citations by year
- 2026: 80 · 2025: 74 · 2024: 83 · 2023: 70 · 2022: 67 · 2021: 70 · 2020: 87 · 2019: 51 · 2018: 34 · 2017: 20
- FWCI
- 30.15
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Licence
- Locations
- Nature Human Behaviour (publishedVersion)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- National Institute on Aging (R01AG030311)
- National Institute of Mental Health (F32MH096533, K01MH096175)
- National Cancer Institute (R25CA102618, U01CA193632, UG1CA189961)
- Army Research Institute for the Behavioral and Social Sciences (W5J9CQ-11-C-0046, W5J9CQ-12-C-0049)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- allostasis, interoception, brain connectivity, convergent validity, mind-body problem, brain functional architecture
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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