Human organs-on-chips for disease modelling, drug development and personalized medicine

Reconstituting organ-level lung functions on a chip

Huh, D., Matthews, B. D., Mammoto, A., Montoya-Zavala, M., Hsin, H. Y., & Ingber, D. E. (2010) · Science · doi:10.1126/science.1188302 · Cited by 4,250

Modeling Development and Disease with Organoids

Clevers, H. (2016) · Cell · doi:10.1016/j.cell.2016.05.082 · Cited by 3,196

Genomic responses in mouse models poorly mimic human inflammatory diseases

Seok, J., Warren, H. S., Cuenca, A. G., Mindrinos, M. N., Baker, H. V., Xu, W., Richards, D. R., McDonald-Smith, G. P., Gao, H., Hennessy, L., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222878110 · Cited by 3,005

PDMS absorption of small molecules and consequences in microfluidic applications

Toepke, M. W., & Beebe, D. J. (2006) · Lab on a Chip · doi:10.1039/b612140c · Cited by 1,193

Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: A review

Fogel, D. B. (2018) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2018.08.001 · Cited by 1,035

Advances in organ-on-a-chip engineering

Zhang, B., Korolj, A., Lai, B. F. L., & Radisic, M. (2018) · Nature Reviews Materials · doi:10.1038/s41578-018-0034-7 · Cited by 1,017

A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice

Huh, D., Leslie, D. C., Matthews, B. D., Fraser, J. P., Jurek, S., Hamilton, G. A., Thorneloe, K. S., McAlexander, M. A., & Ingber, D. E. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004249 · Cited by 993

Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip

Zhang, Y. S., Arneri, A., Bersini, S., Shin, S.-R., Zhu, K., Goli-Malekabadi, Z., Aleman, J., Colosi, C., Busignani, F., Dell’Erba, V., et al. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.09.003 · Cited by 979

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

Kim, H. J., Li, H., Collins, J. J., & Ingber, D. E. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1522193112 · Cited by 922

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

Jang, K., Mehr, A. P., Hamilton, G. A., McPartlin, L. A., Chung, S., Suh, K. Y., & Ingber, D. E. (2013) · Integrative Biology · doi:10.1039/c3ib40049b · Cited by 867

World’s First Long-Term Colorectal Cancer Model by 3D Bioprinting as a Mechanism for Screening Oncolytic Viruses

McGUCKIN, C. P., Forraz, N., Milet, C., Lacroix, M., Sbirkov, Y., Sarafian, V. S., Ebel, C., Spindler, A., Koerper, V., Balloul, J., et al. (2023) · Cancers · doi:10.3390/cancers15194724 · Cited by 21

Microphysiological Constructs and Systems: Biofabrication Tactics, Biomimetic Evaluation Approaches, and Biomedical Applications

Zhang, S., Xu, G., Wu, J., Liu, X., Fan, Y. Z., Chen, J., Wallace, G. G., & Gu, Q. (2023) · Small Methods · doi:10.1002/smtd.202300685 · Cited by 26

The therapeutic potential of immunoengineering for systemic autoimmunity

McBride, D. A., Jones, R. M., Bottini, N., & Shah, N. J. (2024) · Nature Reviews Rheumatology · doi:10.1038/s41584-024-01084-x · Cited by 24

Microphysiological systems as reliable drug discovery and evaluation tools: Evolution from innovation to maturity

Moon, H., Surianarayanan, N., Singh, T., & Han, B. (2023) · Biomicrofluidics · doi:10.1063/5.0179444 · Cited by 21

A functional aged human iPSC‐cortical neuron model recapitulates Alzheimer's disease, senescence, and the response to therapeutics

Gallo, L. H., Akanda, N., Autar, K., Patel, A., Cox, I. M., Powell, H. A., Grillo, M., Barakat, N. M., Morgan, D., Guo, X., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14044 · Cited by 22

Organoid, organ-on-a-chip and traditional Chinese medicine

Yang, J., Jiang, Y., Li, M., Wu, K., Wei, S., Zhao, Y., Shen, J., Du, F., Chen, Y., Deng, S., et al. (2025) · Chinese Medicine · doi:10.1186/s13020-025-01071-8 · Cited by 23

Light-activated semiconductor gas sensors: pathways to improve sensitivity and reduce energy consumption

Nasriddinov, A., Zairov, R., & Rumyantseva, M. N. (2025) · Frontiers in Chemistry · doi:10.3389/fchem.2025.1538217 · Cited by 22

Advanced liver-on-chip model mimicking hepatic lobule with continuous microvascular network via high-definition laser patterning

Watanabe, M., Salvadori, A., Marković, M., Sudo, R., & Ovsianikov, A. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101643 · Cited by 20

A next-generation system for smoke inhalation integrated with a breathing lung-on-chip to model human lung responses to cigarette exposure

Sengupta, A., Schmid, S., Grangier, N., Dorn, A., Hebestreit, M., Hugi, A., Žajdlíková, K., Herbst, A., Losada-Oliva, P., Ortolf-Wahl, H., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-00438-z · Cited by 20

Mechanobiology in Action: Biomaterials, Devices, and the Cellular Machinery of Force Sensing

Lucariello, M., Valicenti, M. L., Giannoni, S., Donati, L., Armentano, I., Morena, F., & Martino, S. (2025) · Biomolecules · doi:10.3390/biom15060848 · Cited by 21

Genomics of drug target prioritization for complex diseases

Chen, R. K., Duffy, Á., & Do, R. (2025) · Nature Reviews Genetics · doi:10.1038/s41576-025-00904-4 · Cited by 28

New developments and applications of human organoids

Andersson-Rolf, A., & Clevers, H. C. (2026) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-026-00974-0 · Cited by 25

Nanocarrier‐Based Drug Delivery Systems using Microfluidic‐Assisted Techniques

Alam, M. K. (2023) · Advanced NanoBiomed Research · doi:10.1002/anbr.202300041 · Cited by 21

Microinstrumentation for Brain Organoids

Patel, D., Shetty, S., Acha, C., Pantoja, I. E. M., Zhao, A., George, D., & Gracias, D. H. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202302456 · Cited by 21

It’s Time to Review the Three Rs, to Make them More Fit for Purpose in the 21st Century

Bailey, J. (2024) · Alternatives to Laboratory Animals · doi:10.1177/02611929241241187 · Cited by 20

Trends in organ-on-a-chip for pharmacological analysis

Xu, X., Cheung, S., Jia, X., Fan, G., Ai, Y., Zhang, Y., & Liang, Q. (2024) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2024.117905 · Cited by 20

Complex in vitro models positioned for impact to drug testing in pharma: a review

Kang, S., Chen, E. C., Cifuentes, H., Co, J. Y., Cole, G., Graham, J. C., Hsia, I., Kiyota, T., Klein, J. A., Kroll, K. T., et al. (2024) · Biofabrication · doi:10.1088/1758-5090/ad6933 · Cited by 22

Human Cell‐Derived Matrix Composite Hydrogels with Diverse Composition for Use in Vasculature‐on‐chip Models

Doherty, E. L., Krohn, G., Warren, E. C., Patton, A., Whitworth, C. P., Rathod, M., Biehl, A., Aw, W. Y., Freytes, D. O., & Polacheck, W. J. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400192 · Cited by 19

Human Tendon‐on‐Chip: Unveiling the Effect of Core Compartment‐T Cell Spatiotemporal Crosstalk at the Onset of Tendon Inflammation

Bakht, S. M., Pardo, A., Gómez‐Florit, M., Caballero, D., Kundu, S. C., Reis, R. L., Domingues, R. M. A., & Gomes, M. E. (2024) · Advanced Science · doi:10.1002/advs.202401170 · Cited by 19

A Human Brain-Chip for Modeling Brain Pathologies and Screening Blood–Brain Barrier Crossing Therapeutic Strategies

Chim, S. M., Howell, K., Kokkosis, A. G., Zambrowicz, B., Karalis, K. P., & Pavlopoulos, E. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16101314 · Cited by 22

Microsensor systems for cell metabolism – from 2D culture to organ-on-chip (2019–2024)

Dornhof, J., Kieninger, J., Rupitsch, S. J., & Weltin, A. (2025) · Lab on a Chip · doi:10.1039/d4lc00437j · Cited by 19

Intestine‐on‐a‐chip for intestinal disease study and pharmacological research

Zhang, D., & Qiao, L. (2022) · Open Research (University of Surrey) · doi:10.1002/viw.20220037 · Cited by 20

Controlling Microenvironments with Organs-on-Chips for Osteoarthritis Modelling

Ong, L. J. Y., Fan, X., Sun, A. R., Mei, L., Toh, Y., & Prasadam, I. (2023) · Cells · doi:10.3390/cells12040579 · Cited by 20

Writing 3D In Vitro Models of Human Tendon within a Biomimetic Fibrillar Support Platform

Monteiro, R. F., Bakht, S. M., Gómez‐Florit, M., Stievani, F. D. C., Alves, A. L. G., Reis, R. L., Gomes, M. E., & Domingues, R. M. A. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c22371 · Cited by 20

Self-assembled innervated vasculature-on-a-chip to study nociception

Kumar, V., Kingsley, D., Perikamana, S. M., Mogha, P., Goodwin, C. R., & Varghese, S. (2023) · Biofabrication · doi:10.1088/1758-5090/acc904 · Cited by 19

Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip

Xue, J., Li, Z., Li, X., Hua, C., Shang, P., Zhao, J., Liu, K., & Xie, F. (2023) · Food and Chemical Toxicology · doi:10.1016/j.fct.2023.113787 · Cited by 20

Engineered Vasculature for Cancer Research and Regenerative Medicine

Nguyen, H. T., Peirsman, A., Tirpáková, Z., Mandal, K., Vanlauwe, F., Maity, S., Kawakita, S., Khorsandi, D., Herculano, R. D., Umemura, C., et al. (2023) · Micromachines · doi:10.3390/mi14050978 · Cited by 19

Transformative Materials to Create 3D Functional Human Tissue Models In Vitro in a Reproducible Manner

Gerardo‐Nava, J., Jansen, J., Günther, D., Klasen, L., Thiebes, A. L., Nießing, B., Bergerbit, C., Meyer, A. A., Linkhorst, J., Barth, M., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301030 · Cited by 19

Advances in the knowledge and therapeutics of schizophrenia, major depression disorder, and bipolar disorder from human brain organoid research

Villanueva, R. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1178494 · Cited by 20

A Microfluidic Organ-On-A-Chip: Into the Next Decade of Bone Tissue Engineering Applied in Dentistry

Syahruddin, M. H., Anggraeni, R., & Ana, I. D. (2023) · Future Science OA · doi:10.2144/fsoa-2023-0061 · Cited by 20

Integrating Liver-Chip data into pharmaceutical decision-making processes

Levner, D., & Ewart, L. C. (2023) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2023.2255127 · Cited by 20

Patient‐derived organoid culture in epithelial ovarian cancers—Techniques, applications, and future perspectives

Chan, W. S., Mo, X.-T., Ip, P. P. C., & Tse, K. Y. (2023) · Cancer Medicine · doi:10.1002/cam4.6521 · Cited by 20

Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations

Lim, A. Y., Kato, Y., Sakolish, C., Valdiviezo, A., Han, G., Bajaj, P., Stanko, J. P., Ferguson, S., Villenave, R., Hewitt, P. G., et al. (2023) · Bioengineering · doi:10.3390/bioengineering10101195 · Cited by 19

From cells to organs: progress and potential in cartilaginous organoids research

Wang, X., Liu, N., Zhang, H., Yin, Z., & Zha, Z.-G. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04591-9 · Cited by 20

Revolutionizing diabetic wound healing: Targeted therapeutic strategies based on growth factors

Yadav, J. P., Patel, D. K., Verma, A., & Pathak, P. (2024) · Obesity Medicine · doi:10.1016/j.obmed.2024.100535 · Cited by 19

In Vitro Models for Peripheral Nerve Regeneration

Tusnim, J., Kutuzov, P., & Grasman, J. M. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202401605 · Cited by 19

Improving tumor microenvironment assessment in chip systems through next-generation technology integration

Gaebler, D., Hachey, S. J., & Hughes, C. C. W. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1462293 · Cited by 20

Droplet microfluidics: unveiling the hidden complexity of the human microbiome

Xu, Y., Wang, Z., Li, C., Tian, S., & Du, W. (2025) · Lab on a Chip · doi:10.1039/d4lc00877d · Cited by 21

Vascularizing organoids-on-chip for perfused and personalized models

Menzani, B., Gea, P. D., Gidrol, X., & Tubbs, E. (2026) · Lab on a Chip · doi:10.1039/d5lc00890e · Cited by 20

Construction and application of liver cancer models in vitro

Shao, C., Zhang, Q., Kuang, G., Fan, Q., & Ye, F. (2022) · Engineered Regeneration · doi:10.1016/j.engreg.2022.07.004 · Cited by 19

In silico modeling of endocrine organ-on-a-chip systems

Sung, B. (2022) · Mathematical Biosciences · doi:10.1016/j.mbs.2022.108900 · Cited by 20

Engineering the Immune Microenvironment into Organoid Models

Luckett, K. A., & Ganesh, K. (2023) · Annual Review of Cancer Biology · doi:10.1146/annurev-cancerbio-061421-040659 · Cited by 20

Modeling human liver organ development and diseases with pluripotent stem cell-derived organoids

Ouchi, R., & Koike, H. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1133534 · Cited by 17

Microfluidic platforms in diagnostic of ovarian cancer

Moghaddam, F. D., Dadgar, D., Esmaeili, Y., Babolmorad, S., Ilkhani, E., Rafiee, M., Wang, X., & Makvandi, P. (2023) · Environmental Research · doi:10.1016/j.envres.2023.117084 · Cited by 18

Engineering Innervated Musculoskeletal Tissues for Regenerative Orthopedics and Disease Modeling

Zhou, Z., Liu, J., Xiong, T., Liu, Y., Tuan, R. S., & Li, Z. A. (2024) · Small · doi:10.1002/smll.202310614 · Cited by 19

Emerging models for studying adipose tissue metabolism

Mora, I., Puiggròs, F., Serras, F., Gil‐Cardoso, K., & Escoté, X. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116123 · Cited by 18

Vascularized tissue on mesh-assisted platform (VT-MAP): a novel approach for diverse organoid size culture and tailored cancer drug response analysis

Lee, J., Jung, S., Hong, H. K., Jo, H., Rhee, S., Jeong, Y., Ko, J., Cho, Y. B., & Jeon, N. L. (2024) · Lab on a Chip · doi:10.1039/d3lc01055d · Cited by 18

Decellularized extracellular matrix-based disease models for drug screening

Chen, Z., Wang, J., Kankala, R. K., Jiang, M., Long, L., Li, W., Zou, L., Chen, A., & Liu, Y. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101280 · Cited by 21

The Modular µSiM Reconfigured: Integration of Microfluidic Capabilities to Study In Vitro Barrier Tissue Models under Flow

Mansouri, M., Ahmed, A., Ahmad, S. D., McCloskey, M. C., Joshi, I. M., Gaborski, T. R., Waugh, R. E., McGrath, J. L., Day, S. W., & Abhyankar, V. V. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202200802 · Cited by 23

Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system

Rigal, S., Casas, B., Kanebratt, K. P., Huldt, C. W., Magnusson, L. U., Müllers, E., Karlsson, F. H., Clausen, M., Hansson, S., Leonard, L., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-06514-w · Cited by 22

In vitro models of the choroid plexus and the blood-cerebrospinal fluid barrier: advances, applications, and perspectives

Schwerk, C., & Schroten, H. (2024) · Human Cell · doi:10.1007/s13577-024-01115-5 · Cited by 17

Bridging the gap: From petri dish to patient - Advancements in translational drug discovery

El‐Tanani, M., Rabbani, S. A., El‐Tanani, Y., Matalka, I. I., & Khalil, I. A. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e41317 · Cited by 17

Bioprinted Organoids: An Innovative Engine in Biomedicine

Li, Z., Li, K., Zhang, C., Zhao, Y., Guo, Y., He, J., Chang, S., Fang, X., Liu, K., Zhu, P., et al. (2025) · Advanced Science · doi:10.1002/advs.202507317 · Cited by 22

High‐Throughput Strategies for Streamlining Lipid Nanoparticle Development Pipeline

Lam, L., Watson, S. L., Ramaswamy, Y., & Singh, G. (2025) · Advanced Science · doi:10.1002/advs.202511551 · Cited by 22

Fabrication and Evaluation of Tubule-on-a-Chip with RPTEC/HUVEC Co-Culture Using Injection-Molded Polycarbonate Chips

Lee, J.-B., Kim, H., Kim, S., & Sung, G. Y. (2022) · Micromachines · doi:10.3390/mi13111932 · Cited by 17

Critical design parameters to develop biomimetic organ-on-a-chip models for the evaluation of the safety and efficacy of nanoparticles

Abdelkarim, M., Pérez-Dávalos, L. A., Abdelkader, Y., Abostait, A., & Labouta, H. I. (2022) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2023.2152000 · Cited by 18

Nanosensor Location Estimation in the Human Circulatory System Using Machine Learning

Gómez, J. T., Kuestner, A., Simonjan, J., Unluturk, B. D., & Dressler, F. (2022) · IEEE Transactions on Nanotechnology · doi:10.1109/tnano.2022.3217653 · Cited by 17

Industry Adoption of Organoids and Organs‐on‐Chip Technology: Toward a Paradox of Choice

Homan, K. A. (2023) · Advanced Biology · doi:10.1002/adbi.202200334 · Cited by 18

Real-time imaging of nanobubble ultrasound contrast agent flow, extravasation, and diffusion through an extracellular matrix using a microfluidic model

Cooley, M. B., Wulftange, W. J., Wegierak, D., Goreke, U., Abenojar, E., Gurkan, U. A., & Exner, A. A. (2023) · Lab on a Chip · doi:10.1039/d3lc00514c · Cited by 18

Mouse Models for Human Herpesviruses

Kutle, I., Dittrich, A., & Wirth, D. (2023) · Pathogens · doi:10.3390/pathogens12070953 · Cited by 17

A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform

Campo, H., Zha, D., Pattarawat, P., Colina, J. A., Zhang, D., Murphy, A. R., Yoon, J., Russo, A., Rogers, H. B., Lee, H. C., et al. (2023) · Lab on a Chip · doi:10.1039/d3lc00378g · Cited by 19

Volatilomes of human infection

Fitzgerald, S., Holland, L., Ahmed, W., Piechulla, B., Fowler, S. J., & Morrin, A. (2023) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-023-04986-z · Cited by 17

Towards skin-on-a-chip for screening the dermal absorption of cosmetics

Govey-Scotland, J., Johnstone, L., Myant, C., & Friddin, M. S. (2023) · Lab on a Chip · doi:10.1039/d3lc00691c · Cited by 17

A Biomimetic Cardiac Fibrosis-on-a-Chip as a Visible Disease Model for Evaluating Mesenchymal Stem Cell-Derived Exosome Therapy

Shang, Y., Sun, L., Gan, J., Xu, D., Zhao, Y., & Sun, L. (2023) · ACS Nano · doi:10.1021/acsnano.3c09368 · Cited by 17

Integrative Approaches for Advancing Organoid Engineering: From Mechanobiology to Personalized Therapeutics

Akhtar, Z. B., & Gupta, A. D. (2024) · Journal of Applied Artificial Intelligence · doi:10.48185/jaai.v5i1.974 · Cited by 16

From animal models to gut-on-chip: the challenging journey to capture inter-individual variability in chronic digestive disorders

Kriaa, A., Mariaule, V., Rudder, C. D., Jablaoui, A., Sokol, H., Wilmes, P., Maguin, E., & Rhimi, M. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2333434 · Cited by 19

Particle Beam Radiobiology Status and Challenges: A PTCOG Radiobiology Subcommittee Report

Ahmad, R., Barcellini, A., Baumann, K. S., Benje, M., Bender, T., Bragado, P., Charalampopoulou, A., Chowdhury, R., Davis, A. J., Ebner, D. K., et al. (2024) · International Journal of Particle Therapy · doi:10.1016/j.ijpt.2024.100626 · Cited by 18

Dual-Purpose Aptamer-Based Sensors for Real-Time, Multiplexable Monitoring of Metabolites in Cell Culture Media

Yang, Y., Gao, X., Widdicombe, B., Zhang, X., Zielinski, J. L., Cheng, T., Gunatilaka, A., Leung, K. K., Plaxco, K. W., Unnithan, R. R., et al. (2024) · ACS Nano · doi:10.1021/acsnano.4c06813 · Cited by 18

A microengineered 3D human neurovascular unit model to probe the neuropathogenesis of herpes simplex encephalitis

Zhang, M., Wang, P., Wu, Y., Jin, L., Liu, J., Deng, P., Luo, R., Chen, X., Zhao, M., Zhang, X. D., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59042-4 · Cited by 18

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Kim, M.-J., Choi, K., Lin, A., & Kim, J. (2025) · Advanced Biology · doi:10.1002/adbi.202400571 · Cited by 16

Complement-ARIE: Catalyzing the development and adoption of new approach methodologies

Sunderic, K., Wright, A. M., Kleinstreuer, N., Ledbetter, V., Milora, K. A., Happel, C., Shaughnessy, D. T., Peñalber‐Johnstone, C., Casco, D. A., Macioce, N., et al. (2025) · NAM journal. · doi:10.1016/j.namjnl.2025.100026 · Cited by 16

Advanced Microfluidics for Single Cell‐Based Cancer Research

Carneiro, A., Palomer, M. A., Esteves, M., Rodrigues, C., Fernandes, J. M., Oliveira, F. A. D. S. D. S., Teixeira, A., Honrado, C., Diéguez, L., Abalde‐Cela, S., et al. (2025) · Advanced Science · doi:10.1002/advs.202500975 · Cited by 17

High-Yield In Situ Growth of Supported Gold Nanorods in Microfluidic Channels

Lonza, M., Vinnacombe‐Willson, G. A., Bevilacqua, F., Scarabelli, L., & Liz‐Marzán, L. M. (2025) · ACS Nano · doi:10.1021/acsnano.5c09672 · Cited by 17

Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer

Campisi, M., Osaki, T., Dryg, I., Stornante, C., Wolff, J., Weirather, J. L., Weaver, N. C., Tarannum, M., Gillanders, I., Bers, A. E., et al. (2026) · Cancer Cell · doi:10.1016/j.ccell.2026.02.008 · Cited by 16

Advances and applications of organ-on-a-chip technology

Kong, J. S., Kim, J., Jang, J., & Cho, D.-W. (2026) · Cell Reports Methods · doi:10.1016/j.crmeth.2026.101361 · Cited by 17

Author Guide for Addressing Animal Methods Bias in Publishing

Krebs, C. E., Camp, C., Constantino, H., Courtot, L., Kavanagh, O. V., McCarthy, J., Ort, M., Sarasija, S., & Trunnell, E. R. (2023) · Advanced Science · doi:10.1002/advs.202303226 · Cited by 18

Cardiovascular human organ‐on‐a‐chip platform for disease modeling, drug development, and personalized therapy

Khanna, A., Oropeza, B. P., & Huang, N. F. (2023) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37602 · Cited by 20

Dynamic tissue model in vitro and its application for assessment of microplastics-induced toxicity to air-blood barrier (ABB)

Fu, A., Mao, S., Kasai, N., Zhu, H., & Zeng, H. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115858 · Cited by 17

Decellularized plant-derived vasculature-on-a-chip interacting with breast cancer spheroids to evaluate a dual-drug therapy

Filiz, Y., Arslan, Y., Duran, E., Saglam‐Metiner, P., Horozoglu, S., Paradiso, A., Martinez, D. C., Takanlou, M. S., Heljak, M. K., Jaroszewicz, J., et al. (2023) · Applied Materials Today · doi:10.1016/j.apmt.2023.102015 · Cited by 17

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Zwi‐Dantsis, L., Jayarajan, V., Church, G. M., Kamm, R. D., de Magalhães, J. P., & Moeendarbary, E. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202500217 · Cited by 16

Ciprofloxacin exacerbates dysfunction of smooth muscle cells in a microphysiological model of thoracic aortic aneurysm

Xiang, B., Abudupataer, M., Liu, G., Zhou, X., Liu, D., Zhu, S., Yang, M., Yin, X., Yan, S., Sun, Y., et al. (2022) · JCI Insight · doi:10.1172/jci.insight.161729 · Cited by 15

Fibrosis‐on‐Chip: A Guide to Recapitulate the Essential Features of Fibrotic Disease

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