Human organs-on-chips for disease modelling, drug development and personalized medicine

Reconstituting organ-level lung functions on a chip

Huh, D., Matthews, B. D., Mammoto, A., Montoya-Zavala, M., Hsin, H. Y., & Ingber, D. E. (2010) · Science · doi:10.1126/science.1188302 · Cited by 4,250

Modeling Development and Disease with Organoids

Clevers, H. (2016) · Cell · doi:10.1016/j.cell.2016.05.082 · Cited by 3,196

Genomic responses in mouse models poorly mimic human inflammatory diseases

Seok, J., Warren, H. S., Cuenca, A. G., Mindrinos, M. N., Baker, H. V., Xu, W., Richards, D. R., McDonald-Smith, G. P., Gao, H., Hennessy, L., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222878110 · Cited by 3,005

PDMS absorption of small molecules and consequences in microfluidic applications

Toepke, M. W., & Beebe, D. J. (2006) · Lab on a Chip · doi:10.1039/b612140c · Cited by 1,193

Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: A review

Fogel, D. B. (2018) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2018.08.001 · Cited by 1,035

Advances in organ-on-a-chip engineering

Zhang, B., Korolj, A., Lai, B. F. L., & Radisic, M. (2018) · Nature Reviews Materials · doi:10.1038/s41578-018-0034-7 · Cited by 1,017

A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice

Huh, D., Leslie, D. C., Matthews, B. D., Fraser, J. P., Jurek, S., Hamilton, G. A., Thorneloe, K. S., McAlexander, M. A., & Ingber, D. E. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004249 · Cited by 993

Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip

Zhang, Y. S., Arneri, A., Bersini, S., Shin, S.-R., Zhu, K., Goli-Malekabadi, Z., Aleman, J., Colosi, C., Busignani, F., Dell’Erba, V., et al. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.09.003 · Cited by 979

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

Kim, H. J., Li, H., Collins, J. J., & Ingber, D. E. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1522193112 · Cited by 922

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

Jang, K., Mehr, A. P., Hamilton, G. A., McPartlin, L. A., Chung, S., Suh, K. Y., & Ingber, D. E. (2013) · Integrative Biology · doi:10.1039/c3ib40049b · Cited by 867

A microfluidic model of human dental pulp angiogenesis for preclinical drug and biomaterial testing

Svanberg, S., Hanoune, M., Mitsiadis, T. A., & Dittrich, P. S. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.102776 · Cited by 4

Multimodal profiling of CAR T cells against glioblastoma using a microengineered 3D tumor-on-a-chip model

Ravi, K., Trottier, S., Amissah, O. B., Russell, G. C., Rho, D., Kim, G. B., & Nikkhah, M. (2026) · Bioactive Materials · doi:10.1016/j.bioactmat.2026.01.003 · Cited by 6

Biological Principles for Success in Alveolar Bone, Soft Tissue, and Periodontal Regeneration

Latimer, J. M., Wu, D. T. S., Yilmaz, B. T., Cha, J., Gouveia, Z., Yao, Y., & Giannobile, W. V. (2026) · Journal of Periodontal Research · doi:10.1111/jre.70068 · Cited by 4

Patient-derived organoids (PDOs): a novel preclinical platform to overcome challenges in cancer immunotherapy

Ni, D., Xing, J., Niu, G., Qiu, J., Wei, G., Chen, G., Zhou, Q., & Yin, X. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1757516 · Cited by 4

Organoid Models: Revolutionizing Disease Modeling and Personalized Therapeutics

Xue, Z., Yang, R., Liu, Y., & Luo, H. (2026) · Organoids · doi:10.3390/organoids5010009 · Cited by 5

Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling

Wang, J., Li, X., Nicolas, G. M., Cai, Y., Yuan, T., Yan, X., Wang, J., Ruan, C., Wang, Z., Zhang, W., et al. (2026) · Microsystems & Nanoengineering · doi:10.1038/s41378-026-01233-0 · Cited by 4

Microphysiological Systems: Transforming Biomedical and Clinical Research

Sahoo, O. S., Tyagi, A., Sharma, A. K., Gill, G. S., Dhar, R., & Karmakar, S. (2026) · Biotechnology and Bioengineering · doi:10.1002/bit.70229 · Cited by 4

Modelling disc degeneration-induced neurovascular invasion on a chip for chronic low back pain therapeutic testing

Natesan, S., Mohan, T. S., Singh, M., Pandit, P., Samuel, G. L., & Thrivikraman, G. (2026) · Acta Biomaterialia · doi:10.1016/j.actbio.2026.05.037 · Cited by 4

Microfluidic Chip Platforms for Red Blood Cell Storage Lesion Quality Control and Precision Transfusion

Lei, Y., Tian, Y., Yang, J., Liu, B., Zou, H., Hauser, C. A. E., Huang, X., Li, Z. A., & Cui, D. (2026) · Research · doi:10.34133/research.1405 · Cited by 5

Mitigating animal methods bias to reduce animal use and improve biomedical translation

Kavanagh, O. V., & Krebs, C. E. (2024) · Science Progress · doi:10.1177/00368504241253693 · Cited by 4

Recent advances in in vitro models simulating the female genital tract toward more effective intravaginal therapeutic delivery

Silva, B., Marques, E. F., & Gomes, A. C. (2024) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2024.2380338 · Cited by 4

Organs on chips: fundamentals, bioengineering and applications

Awad, N. K. (2024) · Journal of Artificial Organs · doi:10.1007/s10047-024-01460-0 · Cited by 4

Cell line-based in vitro models of normal and chronic bronchitis-like airway mucosa to study the toxic potential of aerosolized palladium nanoparticles

Ji, J., Jansen, K., Kessler, V. G., Seisenbaeva, G. A., Gerde, P., Malmlöf, M., Palmberg, L., & Upadhyay, S. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1422792 · Cited by 4

Microfluidic chip-based nano-carrier-based drug delivery systems and their efficacy assessment using tumor organ chips

Sun, Y., Jin, F., & Gao, D. (2024) · BME Horizon · doi:10.70401/bmeh.2024.136 · Cited by 4

Establishment of the multi-organ circulatory and supervision system (MOCS)

Kang, L., Sheng, J., Bao, X., He, G., Mao, L., Wang, Q., Lu, J., Zhou, M., Zhang, Y., He, L., et al. (2024) · 中国科学通报：英文版 · doi:10.1016/j.scib.2024.12.038 · Cited by 4

Triplicate Dynamic Cell Culture Platform for Enhanced Reproducibility in Anti-Cancer Drug Testing

Lu, Y., Lin, C.-M., & Huang, J. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c02142 · Cited by 4

Future Directions for Quantitative Systems Pharmacology

Schoeberl, B., Musante, C. J., & Ramanujan, S. (2024) · Handbook of experimental pharmacology · doi:10.1007/164_2024_737 · Cited by 5

Real-time and regional analysis of the efficacy of anticancer drugs in a patient-derived intratumoral heterogeneous tumor microenvironment

Lin, Y., Lin, C.-M., Man, K., Hung, C., Hsu, H.-L., Chen, Y., Mu, H., Hsiao, T., & Huang, J. (2025) · Lab on a Chip · doi:10.1039/d4lc00990h · Cited by 4

Unravelling approaches to study macrophages: from classical to novel biophysical methodologies

Vishnyakova, P., Elchaninov, A. V., Fatkhudinov, T., & Kolesov, D. V. (2025) · PeerJ · doi:10.7717/peerj.19039 · Cited by 4

Protocols to co-culture human primary lung cells in the simple-flow device

Iriondo, C., Koornneef, S., Skarp, K., Kempen, M. B., Munck, A. B., & Rottier, R. J. (2025) · STAR Protocols · doi:10.1016/j.xpro.2025.103892 · Cited by 4

Lost in translation: rethinking animal models of progressive MS (an industry perspective)

von Raison, F., Zaratin, P., Stangel, M., Shimshek, D. R., Nuesslein‐Hildesheim, B., Locatelli, G., Collin, L., Foo, L. C., Jafari, M., Peelen, E., et al. (2025) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2025.106644 · Cited by 4

The influence of bodily fluid rheology on biofilm formation: known facts and open questions

Savorana, G., Claudio, A. D., Rusconi, R., & Secchi, E. (2025) · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · doi:10.1098/rsta.2024.0267 · Cited by 5

Bridging the prevention gap: funding distribution and methodological shifts in prevention-focused biomedical research under EU framework programmes

Pistollato, F., Furtmann, F., Gastaldello, A., Pastorino, R., Petra, E., Tripodi, I. J., & Constantino, H. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07019-8 · Cited by 4

Impact of methotrexate-loaded fattigated albumin nanoparticles and pharmaceutical excipients on real-time reactive oxygen species and cell viability in a microfluidic chip system

Abdullah, S. S., Kim, E.-J., Lee, J., Nguyen, H. D., & Lee, B. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.126259 · Cited by 4

The chemokines CCL22 and CCL17 are a defining feature of type 2 stimulated human lung macrophages and exhibit different metabolic dependencies

Ridley, A. J. L., Curle, A. J., Colombo, S. A. P., Hughes, J. J., Dyer, D. P., Simpson, A., Booty, L. M., Feeney, M. B., Cook, P. C., & MacDonald, A. S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1654717 · Cited by 4

Advancing Organ‐on‐Chip Models With a Sacrificial Granular Hydrogel Strategy for Enhanced Permeability and Biomimicry

Caires, H. R., Castillo‐Fernández, Ó., Sima, N., Magalhães, M. V., Benavent‐Claró, A., Masó‐Castro, N., Roobsoong, W., Fernández-Becerra, C., Hernández-Machado, A., Portillo, H. A. D., et al. (2025) · Small Methods · doi:10.1002/smtd.202500652 · Cited by 4

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

Burckart, G. J., Abdel‐Rahman, S. M., Abulwerdi, G. A., Samuels, S., Racz, R., Mohamoud, M., & Tatonetti, N. P. (2025) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.70148 · Cited by 4

Role of solute carrier transporters in the biodistribution and toxicity of chemotherapeutic drugs

Boeckman, M., Drabison, T., Germakovski, A., Warmuth, A., Ahmed, B., Chowdhury, A. T., Hu, S., Sprowl, J. A., Sparreboom, A., & Huang, K. M. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100117 · Cited by 4

Sepsis modelling: current approaches and organ-on-chip perspectives

Silva, M. J., Fehrenbach, G. W., Pogue, R. E., Murray, P., Rezoagli, E., Laffey, J. G., & Murphy, E. J. (2026) · EBioMedicine · doi:10.1016/j.ebiom.2026.106120 · Cited by 6

Online supervised learning of temporal patterns in biological neural networks under feedback control

Sono, Y., Yamamoto, H., Nishi, Y., Sumi, T., Sato, Y., Hirano‐Iwata, A., Katori, Y., & Sato, S. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2521560123 · Cited by 9

Human Organoids and Organ-on-Chip for Biotoxin Assessment: Applications, Best Practices, and a Translational Roadmap

Li, M., Huang, S., Jia, J., Feng, Y., & Zhang, J. (2026) · Toxins · doi:10.3390/toxins18030149 · Cited by 4

Advances in In Vitro Blood-Air Barrier Models and the Use of Nanoparticles in COVID-19 Research

Özdemir, N. S., Belyaev, D., Castro, M. N., Balakin, S., Opitz, J. L., Wihadmadyatami, H., Anggraeni, R., Yücel, D., Kenar, H., Beshchasna, N., et al. (2023) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2023.0117 · Cited by 7

Transitioning biomedical research toward human-centric methodologies: systems-based strategies

Constantino, H., Pistollato, F., & Seidle, T. (2024) · Drug Discovery Today · doi:10.1016/j.drudis.2024.103947 · Cited by 4

Vasculature-on-a-chip technologies as platforms for advanced studies of bacterial infections

Gaudreau, L. I., & Stewart, E. K. (2024) · Biomicrofluidics · doi:10.1063/5.0179281 · Cited by 5

Neuroinflammation-on-a-chip for multiple sclerosis research: a narrative review

Berjaoui, C., Kachouh, C., Joumaa, S., Hussein Ghayyad, M., Abate Bekele, B., Ajirenike, R., Al Maaz, Z., Awde, S., Wojtara, M., Nazir, A., et al. (2024) · Annals of Medicine & Surgery · doi:10.1097/ms9.0000000000002231 · Cited by 4

Microfluidic-based modeling of human tissue barriers

Lee, S., Shin, M., & Ahn, S. I. (2024) · JMST Advances · doi:10.1007/s42791-024-00077-x · Cited by 4

Engineered microenvironments and pancreatic islet-on-chips for screening sugar substitute and antidiabetic compounds

Shi, J., Li, J., Su, W., Xue, C., Zhang, Y., & Gao, X. (2024) · Food Research International · doi:10.1016/j.foodres.2024.115084 · Cited by 4

Evolution of toxicity testing platforms from 2D to advanced 3D bioprinting for safety assessment of drugs

Shyam, R., Singh, R., Bajpai, M., Palaniappan, A., & Parthasarathi, R. (2024) · Bioprinting · doi:10.1016/j.bprint.2024.e00363 · Cited by 4

An engineered palivizumab IgG2 subclass for synthetic gp130 and fas-mediated signaling

Wittich, C., Ettich, J., Hertell, M., Roy, B. G., Xu, H. C., Floss, D. M., Lang, P. A., & Scheller, J. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108205 · Cited by 4

Absorption of Toxicants from the Ocular Surface: Potential Applications in Toxicology

Šoša, I., Perković, M., Šoša, I. B., Grubešić, P., Linšak, D. T., & Strenja-Linić, I. (2025) · Biomedicines · doi:10.3390/biomedicines13030645 · Cited by 4

Emerging supramolecular and living materials in oral medicine

Fischer, N. G., Lin, T.-Y., Xiang, Y., Sang, T., & Ye, Z. (2025) · Trends in biotechnology · doi:10.1016/j.tibtech.2025.03.006 · Cited by 4

From bench to bedside: The evolution of extracellular vesicle diagnostics through microfluidic and paper-based technologies

Praveena, G., Jayachandran, A., Manda, S. V., & Asthana, A. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.114675 · Cited by 5

Recent advances in health biotechnology during pandemic

Aslan, A., Alhamwı, S., Kurtur, O. B., GÜNDÜZ, O., Çakan, D., Üstündağ, C. B., Doymuş, B., Topuzoğulları, M., Yilmaz, B. B., Gök, B., et al. (2023) · Sigma Journal of Engineering and Natural Sciences – Sigma Mühendislik ve Fen Bilimleri Dergisi · doi:10.14744/sigma.2023.00065 · Cited by 5

Integrating Early-Stage Drug Development with Clinical Networks; Challenges and Opportunities: The City of Hope Developing Experience

Villalona-Calero, M. A., Malhotra, J. D., Chung, V. M., Xing, Y., Gray, S. W., Hampel, H., Gruber, S. B., & McDonnell, K. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12124061 · Cited by 4

Engineering Tendon Assembloids to Probe Cellular Crosstalk in Disease and Repair

Stauber, T., Wolleb, M., & Snedeker, J. G. (2024) · Journal of Visualized Experiments · doi:10.3791/65987 · Cited by 4

Immunoengineering for autoimmune-kidney disease

Mirioğlu, Ş., Bruchfeld, A. N., Caravaca‐Fontán, F., Juarez, G. M. F., Floege, J., Frangou, E. A., Goumenos, D. S., Griffith, M. E., Moran, S. M., Stevens, K., et al. (2024) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfae140 · Cited by 4

The Applications of Microphysiological Systems in Biomedicine: Impact on Urologic and Orthopaedic Research

Caetano-Pinto, P., & Schoon, J. (2022) · Encyclopedia · doi:10.3390/encyclopedia2020075 · Cited by 4

Agency in the Evolutionary Transition to MulticellularityPreprint

Newman, S. A., Benítez, M., Bhat, R., Glimm, T., Kumar, K. V., Nanjundiah, V., Nicholson, D. J., & Sarkar, S. (2024) · doi:10.32942/x2x895 · Cited by 4

Combining Scalable Organ Chip Platform with Deep Learning-Based Imaging Analysis for Cancer Therapeutic ScreeningPreprint

Yuan, Y., Xu, B., McCormack, J., Huang, X., Ma, J., Marshall, T., Sun, Y., Singh, H., Fanelli, A., Gilbride, P., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.10.598272 · Cited by 4

Utilizing Omics Technologies and Machine Learning to Improve Predictive ToxicologyPreprint

Son, A., Park, J., Kim, W., Yoon, Y., Lee, S., & Kim, H. (2024) · Preprints.org · doi:10.20944/preprints202408.1827.v1 · Cited by 3

A Microphysiologic Model of the Cervical Epithelium Recapitulates Microbial, Immunologic, and Pathogenic Properties of Sexually Transmitted InfectionsPreprint

Nelson, K. M., Minahan, D. J., Edwards, V. L., Glomski, I. J., Delgado-Diaz, D. J., Thomas, K. S., Walker, F. C., Bavoil, P. M., Derré, I., Criss, A. K., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.21.665989 · Cited by 4

A high-throughput microphysiological system to quantify key events leading to liver fibrosis

Schmidt, S., & Suter-Dick, L. (2025) · Toxicology · doi:10.1016/j.tox.2025.154248 · Cited by 3

Modeling fire‐related smoke inhalation injury using the human lung‐on‐a‐chip and organoid platform: Pathogenesis insights and therapeutic evaluation

Li, J., Zhang, D., Meng, Y., Chang, Y.-Q., Wei, W., Wu, P. F., Peng, L., Chang, W., Wang, W., Huang, J., et al. (2025) · Open Research (University of Surrey) · doi:10.1002/viw.20240114 · Cited by 3

Examining the Toxicological Landscape of New Molecular Entities and Biotherapeutics

Narayanan, P. (2025) · Springer eBooks · doi:10.1007/978-3-031-81787-8_10 · Cited by 3

Cell Ratio-Dependent Osteoblast–Endothelial Cell Crosstalk Promoting Osteogenesis–Angiogenesis Coupling via Regulation of Microfluidic Perfusion and Paracrine Signaling

Wang, Y., Chen, S., Fan, W., Zhang, S., & Chen, X. (2025) · Micromachines · doi:10.3390/mi16050539 · Cited by 3

Recent advances and future perspectives of long-acting ophthalmic preparations (LAOPs) in clinical applications

Wang, B., Zhang, M., Chen, W., Yin, C., Zhao, H., Chen, G., & Cao, F. (2025) · Biomaterials Science · doi:10.1039/d5bm00453e · Cited by 3

Dose Optimization of ClpP Agonists Using an In Vitro Microfluidic Perfusion Platform and In Silico Pharmacokinetic-Pharmacodynamic Modeling

Bucher, R. W., Graves, L. M., & Bartlett, D. W. (2025) · The AAPS Journal · doi:10.1208/s12248-025-01088-9 · Cited by 3

Tissue is the issue: overcoming limitations in lung cancer precision medicine through cryobiopsy-derived lung cancer organoids and organ-on-a-chip models

Kim, Y., Park, D., Lee, D. H., & Chung, C. (2025) · Experimental Cell Research · doi:10.1016/j.yexcr.2025.114642 · Cited by 3

Experimental dissection of tuberculosis protective immunity: a human perspective

Schmidiger, S., & Portevin, D. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1595076 · Cited by 3

Rapid Prototyping of Tape-Based Microfluidic Chips With Versatile On-Chip Fluidic Functions

Wu, Z., Ma, G., Wang, A., Zhang, G., Zhong, S., Zhao, K., Wang, Q., Li, Y., & Chen, K. P. (2025) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2025.3580421 · Cited by 3

Tumor Immune Engineering: Developing In Vitro Assays to Understand the Tumor–Immune Crosstalk

Iyer, R. N., Vartak, M., & Dey, T. (2025) · Advanced Biology · doi:10.1002/adbi.202400735 · Cited by 3

Advanced cell-adaptable hydrogels for bioprinting

Li, L., Wu, W., Zhu, Q., Peng, M., Dong, Y., Liu, H., Zhang, J., & Gou, M. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.07.044 · Cited by 7

Human neutrophil-derived extracellular vesicles induce renal endothelial inflammation in critical illness: an ex vivo investigation

Stephens, J. R., Iki, Y., Yasuda, T., Brown, E., Tsiridou, D. M., Green, A., Patel, P., Waheed, U., Stümpfle, R., Ratnayake, A., et al. (2025) · British Journal of Anaesthesia · doi:10.1016/j.bja.2025.06.030 · Cited by 3

Comparative information of different animal models used in chronic diseases

Goel, F., Giri, A., Kumar, D., Pal, A., & Singh, P. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-33877-9.00014-8 · Cited by 3

Inner Ear Organoids: A Hydrogel-Based Platform for Drug Screening and Deafness Modeling

Cao, Y., Liu, X., Chai, R., & He, Z. (2025) · Neuroscience Bulletin · doi:10.1007/s12264-025-01479-0 · Cited by 3

Attenuation of blood-brain barrier dysfunction by functionalized gold nanoparticles against amyloid-β peptide in an Alzheimer's disease-on-a-chip model

Tapia-Arellano, A., Palma-Florez, S., Cabrera, P., Cortés-Adasme, E., Bolaños, K., Célis, F., Araya-Vergara, A. J., Pérez, M., Crespo, A., Matus, M. H., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102453 · Cited by 4

Synthetic peptide hydrogels as a model of the bone marrow niche demonstrate efficacy of a combined CRISPR-CAR T-cell therapy for acute myeloid leukaemia

Doherty-Boyd, W. S., Tsimbouri, P. M., Jayawarna, V., Walker, M., Taqi, A. F., Mahon, N., Meek, R. M. D., Young, P. S., Miller, A. F., West, A. G., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123803 · Cited by 3

Targeting cystatin F activation enhances NK cell cytotoxicity in glioblastoma models

Senjor, E., Habič, A., Švajger, U., Mitrović, A., Proj, M., Porčnik, A., Prestor, B., Jerala, M., Bošnjak, M., Gobec, S., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1708281 · Cited by 3

Mechanisms That Prevent Vascular Leakage During Leukocyte Extravasation

de Haan, S. J., & van Buul, J. D. (2025) · Acta Physiologica · doi:10.1111/apha.70126 · Cited by 3

Colorectal Cancer Hepatic Metastasis Modeling by Advanced 3D Bioprinting Allows Demonstration of Oncolytic Viral Chemotherapeutic Delivery

McGUCKIN, C. P., Forraz, N., Milet, C., Lacroix, M., Sbirkov, Y., Sarafian, V. S., Ebel, C., Spindler, A., Koerper, V., Balloul, J., et al. (2025) · Cancers · doi:10.3390/cancers17223705 · Cited by 3

Lymph node paracortex-inspired on-a-chip recapitulating immunosenescence: a cancer vaccine immunogenicity and antitumoral efficacy screening platform

Maity, S., Najafabadi, A. H., Kawakita, S., Khorsandi, D., Yilgor, C., Jewell, C., Mohaghegh, N., Dokmeci, M. R., Khademhosseini, A., & Jucaud, V. (2025) · Lab on a Chip · doi:10.1039/d5lc00533g · Cited by 5

Applications and Complementarity of Organ‐Chips and Animal Models in Lung Cancer Driver Gene Research

Wang, L., Wu, T., & Tsai, F. (2025) · Cell Biology International · doi:10.1002/cbin.70108 · Cited by 3

Biomimetic oral drug delivery: Translating nature’s design into therapeutic innovation

Madny, M. A., & Yadav, K. S. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.115348 · Cited by 5

Molecular Compatibility in Chinese Medicine for Cancer Treatment and Drug Development: From Traditional Wisdom to Innovative Therapeutics

Zhang, R., You, Y., Gao, Q., Sun, X., Zheng, C., & Xie, T. (2025) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-025-4152-y · Cited by 3

A workflow integrating organ-on-chip culture and correlative 3D light and electron microscopy for microtissue analysis

Schaart, J. M., Wasserberg, D., Cruz, M. A. E., Lindert, M. K., van der Meijden, R. H. M., Roverts, R., Debera, N., Lu, M. P., Rouwkema, J., Nijhuis, W. H., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-27587-5 · Cited by 3

Advanced strategies in organoid/organ-on-a-chip for female reproductive diseases

Zhou, Y., Chen, M., Wang, F., Xu, C., Wen, Y., He, Z., & Zhu, Y. (2025) · Biofabrication · doi:10.1088/1758-5090/ae2b10 · Cited by 3

Cell patterning in vivo using microrobot specifically designed for tissue engineering applications

Yamazoe, H., Yamano, Y., Teramura, Y., & Shinzaki, S. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102683 · Cited by 3

Drug resistant cancer cells show increased nuclear mechanotransduction and mechanically targetable YAP-regulated vulnerability

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