Cited by 179Stress Responses and CortisolNeuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

Social transmission and buffering of synaptic changes after stress

Sterley, Toni-Lee, Baimoukhametova, Dinara, Füzesi, Tamás, Zurek, Agnieszka A., Daviu, Nuria, Rasiah, Neilen P., Rosenegger, David, Bains, Jaideep S.·2018·Nature Neuroscience

DOI 10.1038/s41593-017-0044-6

Open this paper in CoChat — free account

Abstract

Stress can trigger enduring changes in neural circuits and synapses. The behavioral and hormonal consequences of stress can also be transmitted to others, but whether this transmitted stress has similar effects on synapses is not known. We found that authentic stress and transmitted stress in mice primed paraventricular nucleus of the hypothalamus (PVN) corticotropin-releasing hormone (CRH) neurons, enabling the induction of metaplasticity at glutamate synapses. In female mice that were subjected to authentic stress, this metaplasticity was diminished following interactions with a naive partner. Transmission from the stressed subject to the naive partner required the activation of PVN CRH neurons in both subject and partner to drive and detect the release of a putative alarm pheromone from the stressed mouse. Finally, metaplasticity could be transmitted sequentially from the stressed subject to multiple partners. Our findings demonstrate that transmitted stress has the same lasting effects on glutamate synapses as authentic stress and reveal an unexpected role for PVN CRH neurons in transmitting distress signals among individuals.

Integrity signals

Registry

Crossref · 10.1038/s41593-017-0044-6

Cites

46 of 46 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight.
Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A. R., & Updegraff, J. A. (2000) · Psychological Review · doi:10.1037/0033-295x.107.3.411 · Cited by 3,308
Development of concern for others.
Zahn-Waxler, C., Radke-Yarrow, M., Wagner, E., & Chapman, M. (1992) · Developmental Psychology · doi:10.1037/0012-1649.28.1.126 · Cited by 1,314
The neurobiology of attachment
Insel, T. R., & Young, L. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35053579 · Cited by 1,173
Promoting social behavior with oxytocin in high-functioning autism spectrum disorders.
Andari, E., Duhamel, J.-R., Zalla, T., Herbrecht, E., Leboyer, M., & Sirigu, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910249107 · Cited by 941
Empathy and pro-social behavior in rats
Bartal, I. B.-A., Decety, J., & Mason, P. (2011) · Science · doi:10.1126/science.1210789 · Cited by 934
Social Modulation of Pain as Evidence for Empathy in Mice
Langford, D. J., Crager, S. E., Shehzad, Z., Smith, S. B., Sotocinal, S. G., Levenstadt, J. S., Chanda, M. L., Levitin, D. J., & Mogil, J. S. (2006) · Science · doi:10.1126/science.1128322 · Cited by 865
Oxytocin-dependent consolation behavior in rodents
Burkett, J. P., Andari, E., Johnson, Z. V., Curry, D. C., de Waal, F. B. M., & Young, L. J. (2016) · Science · doi:10.1126/science.aac4785 · Cited by 692
Distinct representations of olfactory information in different cortical centres
Sosulski, D. L., Bloom, M. L., Cutforth, T., Axel, R., & Datta, S. R. (2011) · Nature · doi:10.1038/nature09868 · Cited by 479
Social buffering of the stress response: diversity, mechanisms, and functions
Hennessy, M. B., Kaiser, S., & Sachser, N. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.06.001 · Cited by 477

Show all 46 references

Sorted by citations

Neurobiological links between stress and anxiety
Daviu, N., Bruchas, M. R., Moghaddam, B., Sandi, C., & Beyeler, A. (2019) · Neurobiology of Stress · doi:10.1016/j.ynstr.2019.100191 · Cited by 591
The future of rodent models in depression research
Gururajan, A., Reif, A., Cryan, J. F., & Slattery, D. A. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0221-6 · Cited by 269
Paraventricular nucleus CRH neurons encode stress controllability and regulate defensive behavior selection
Daviu, N., Füzesi, T., Rosenegger, D. G., Rasiah, N. P., Sterley, T.-L., Peringod, G., & Bains, J. S. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0591-0 · Cited by 217
Self-citation
Stress and perceived social isolation (loneliness)
Campagne, D. M. (2019) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2019.02.007 · Cited by 240
Oxytocin Signaling in the Central Amygdala Modulates Emotion Discrimination in Mice
Ferretti, V., Maltese, F., Contarini, G., Nigro, M., Bonavia, A., Huang, H., Gigliucci, V., Morelli, G., Scheggia, D., Managò, F., et al. (2019) · Current Biology · doi:10.1016/j.cub.2019.04.070 · Cited by 212
Somatostatin interneurons in the prefrontal cortex control affective state discrimination in mice
Scheggia, D., Managò, F., Maltese, F., Bruni, S., Nigro, M., Dautan, D., Latuske, P., Contarini, G., Gomez-Gonzalo, M., Requie, L. M., et al. (2020) · Nature Neuroscience · doi:10.1038/s41593-019-0551-8 · Cited by 192
Protective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice
Mayo, L. M., Asratian, A., Lindé, J., Holm, L., Nätt, D., Augier, G., Stensson, N., Vecchiarelli, H. A., Balsevich, G., Aukema, R. J., et al. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0215-1 · Cited by 175
Neural control of affiliative touch in prosocial interaction
Wu, Y. E., Dang, J., Kingsbury, L., Zhang, M., Sun, F., Hu, R. K., & Hong, W. (2021) · Nature · doi:10.1038/s41586-021-03962-w · Cited by 156
Neural mechanism underlying depressive-like state associated with social status loss
Fan, Z., Chang, J., Liang, Y., Zhu, H. L., Zhang, C., Zheng, D., Wang, J., Xu, Y., Li, Q.-J., & Hu, H. (2023) · Cell · doi:10.1016/j.cell.2022.12.033 · Cited by 149
Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions
Yu, H., Miao, W., Ji, E., Huang, S., Jin, S., Zhu, X., Liu, M.-Z., Sun, Y.-G., Xu, F., & Yu, X. (2022) · Neuron · doi:10.1016/j.neuron.2021.12.022 · Cited by 144
An insular view of the social decision-making network
Rogers-Carter, M. M., & Christianson, J. P. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.06.005 · Cited by 121
Emotional contagion and prosocial behavior in rodents
Keysers, C., Knapska, E., Moita, M. A. P., & Gazzola, V. (2022) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2022.05.005 · Cited by 130
Understanding others: Emotion recognition in humans and other animals
Ferretti, V., & Papaleo, F. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12544 · Cited by 142
Neural basis of prosocial behavior
Wu, Y. E., & Hong, W. (2022) · Trends in Neurosciences · doi:10.1016/j.tins.2022.06.008 · Cited by 137
Hypothalamic circuitry underlying stress-induced insomnia and peripheral immunosuppression
Li, S.-B., Borniger, J. C., Yamaguchi, H., Hédou, J., Gaudilliere, B., & de Lecea, L. (2020) · Science Advances · doi:10.1126/sciadv.abc2590 · Cited by 121
Beyond the three-chamber test: toward a multimodal and objective assessment of social behavior in rodents
Jabarin, R., Netser, S., & Wagner, S. (2022) · Molecular Autism · doi:10.1186/s13229-022-00521-6 · Cited by 119
Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations
Chen, P., Lou, S., Huang, Z., Wang, Z., Shan, Q., Wang, Y., Yang, Y., Li, X., Gong, H., Jin, Y., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.01.033 · Cited by 99
Identification of a neurocircuit underlying regulation of feeding by stress-related emotional responses
Xu, Y., Lu, Y., Cassidy, R. M., Mangieri, L. R., Zhu, C., Xugen, H., Jiang, Z., Justice, N. J., Xu, Y., Arenkiel, B. R., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11399-z · Cited by 98
Embodied stress: The physiological resonance of psychosocial stress
Engert, V., Linz, R., & Grant, J. A. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.12.221 · Cited by 103
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
Kim, J. S., Han, S. Y., & Iremonger, K. J. (2019) · Nature Communications · doi:10.1038/s41467-019-13639-8 · Cited by 88
Chronic Unpredictable Mild Stress Model of Depression: Possible Sources of Poor Reproducibility and Latent Variables
Markov, D. D., & Novosadova, E. V. (2022) · Biology · doi:10.3390/biology11111621 · Cited by 101
Endocannabinoids, cannabinoids and the regulation of anxiety
Petrie, G. N., Nastase, A. S., Aukema, R. J., & Hill, M. N. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108626 · Cited by 91
Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection
Granton, E., Brown, L., Defaye, M., Moazen, P., Almblad, H., Randall, T. E., Rich, J. D., Geppert, A., Abdullah, N. S., Hassanabad, M. F., et al. (2024) · Cell · doi:10.1016/j.cell.2024.03.001 · Cited by 79
Stress‐induced structural and functional modifications of astrocytes—Further implicating glia in the central response to stress
Murphy‐Royal, C., Gordon, G. R., & Bains, J. S. (2019) · Glia · doi:10.1002/glia.23610 · Cited by 80
Dysfunctions of the paraventricular hypothalamic nucleus induce hypersomnia in mice
Chen, C.-R., Zhong, Y.-H., Jiang, S., Xu, W., Wang, Z., Xiao, L., Qu, W.-M., & Huang, Z.-L. (2021) · eLife · doi:10.7554/elife.69909 · Cited by 74
Windows into stress: a glimpse at emerging roles for CRH PVN neurons
Rasiah, N. P., Loewen, S. P., & Bains, J. S. (2023) · Physiological Reviews · doi:10.1152/physrev.00056.2021 · Cited by 62
The social transmission of stress in animal collectives
Brandl, H. B., Pruessner, J. C., & Farine, D. R. (2022) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2021.2158 · Cited by 55
Biological mechanisms for observational learning
Carcea, I., & Froemke, R. C. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.11.008 · Cited by 60
Towards a unified theory of emotional contagion in rodents—A meta-analysis
Hernandez-Lallement, J., Gómez-Sotres, P., & Carrillo, M. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.010 · Cited by 53
Sensory input, sex and function shape hypothalamic cell type development
Kaplan, H. S., Logeman, B. L., Zhang, K., Yawitz, T. A., Santiago, C., Sohail, N., Talay, M., Seo, C., Naumenko, S., Sui, S. J. H., et al. (2025) · Nature · doi:10.1038/s41586-025-08603-0 · Cited by 51
Insights from social transmission of information in rodents
Monfils, M., & Agee, L. A. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12534 · Cited by 56
Optogenetic reactivation of prefrontal social neural ensembles mimics social buffering of fear
Gutzeit, V. A., Ahuna, K., Santos, T. L., Cunningham, A. M., Rooney, M. S., Zamora, A., Denny, C. A., & Donaldson, Z. R. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0631-1 · Cited by 55
Cognitive functions associated with developing prefrontal cortex during adolescence and developmental neuropsychiatric disorders
Sakurai, T., & Gamo, N. J. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.11.007 · Cited by 54
Familiarity modulates social approach toward stressed conspecifics in female rats
Rogers-Carter, M. M., Djerdjaj, A., Culp, A. R., Elbaz, J. A., & Christianson, J. P. (2018) · PLoS ONE · doi:10.1371/journal.pone.0200971 · Cited by 53
Brain circuits that regulate social behavior
Li, H., Zhao, Z., Jiang, S., & Wu, H. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03037-6 · Cited by 67
Insular cortex corticotropin-releasing factor integrates stress signaling with social affective behavior
Rieger, N. S., Varela, J. A., Ng, A. J., Granata, L. E., Djerdjaj, A., Brenhouse, H. C., & Christianson, J. P. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01292-7 · Cited by 50
Convergent neuroendocrine mechanisms of social buffering and stress contagion
Peen, N. F., Duque‐Wilckens, N., & Trainor, B. C. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2021.104933 · Cited by 47
Modulation of Feeding and Associated Behaviors by Lateral Hypothalamic Circuits
Qualls‐Creekmore, E., & Münzberg, H. (2018) · Endocrinology · doi:10.1210/en.2018-00449 · Cited by 45
Temporally Tuned Corticosteroid Feedback Regulation of the Stress Axis
Kim, J. S., & Iremonger, K. J. (2019) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2019.07.005 · Cited by 44
Deletion of CRH From GABAergic Forebrain Neurons Promotes Stress Resilience and Dampens Stress-Induced Changes in Neuronal Activity
Dedic, N., Kühne, C., Gomes, K. S., Hartmann, J., Ressler, K. J., Schmidt, M. V., & Deussing, J. M. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00986 · Cited by 46
Early life adversity shapes social subordination and cell type–specific transcriptomic patterning in the ventral hippocampus
Kos, A., López, J. P., Bordes, J., Donno, C. D., Dine, J., Brivio, E., Karamihalev, S., Luecken, M. D., Almeida-Corrêa, S., Gasperoni, S., et al. (2023) · Science Advances · doi:10.1126/sciadv.adj3793 · Cited by 43
Social communication of affective states
Sterley, T.-L., & Bains, J. S. (2021) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.12.007 · Cited by 43
N‐3 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development
Leyrolle, Q., Decoeur, F., Déjean, C., Brière, G., Leon, S., Bakoyiannis, I., Baroux, E., Sterley, T., Bosch‐Bouju, C., Morel, L., et al. (2021) · Glia · doi:10.1002/glia.24088 · Cited by 43
Vicarious Emotions of Fear and Pain in Rodents
Keysers, C., & Gazzola, V. (2023) · Affective Science · doi:10.1007/s42761-023-00198-x · Cited by 36
Hypothalamic corticotrophin releasing hormone neurons in stress‐induced psychopathology: Revaluation of synaptic contributions
Stanton, L. M., Price, A. J., & Manning, E. E. (2023) · Journal of Neuroendocrinology · doi:10.1111/jne.13268 · Cited by 40
Synaptic Microenvironment in Depressive Disorder: Insights from Synaptic Plasticity
Ren, F., & Guo, R. (2021) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s268012 · Cited by 32
Maturation of amygdala inputs regulate shifts in social and fear behaviors: A substrate for developmental effects of stress
Ferrara, N. C., Trask, S., & Rosenkranz, J. A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.01.021 · Cited by 33
Hypocretin/orexin neurons encode social discrimination and exhibit a sex-dependent necessity for social interaction
Dawson, M., Terstege, D. J., Jamani, N. F., Tsutsui, M., Pavlov, D., Bugescu, R., Epp, J. R., Leinninger, G. M., & Sargin, D. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112815 · Cited by 34
Cellular distribution of PACAP-38 and PACAP receptors in the rat brain: Relation to migraine activated regions
Warfvinge, K., & Edvinsson, L. I. (2019) · Cephalalgia · doi:10.1177/0333102419893962 · Cited by 30
Corticotropin-releasing factor induces functional and structural synaptic remodelling in acute stress
Vandael, D., Wierda, K. D. B., Vints, K., Baatsen, P., Groef, L. D., Moons, L., Rybakin, V., & Gounko, N. V. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01497-2 · Cited by 31
Physical restraint mouse models to assess immune responses under stress with or without habituation
Ding, J. X., Rudak, P. T., Inoue, W., & Haeryfar, S. M. M. (2021) · STAR Protocols · doi:10.1016/j.xpro.2021.100838 · Cited by 30
Social context and dominance status contribute to sleep patterns and quality in groups of freely-moving mice
Karamihalev, S., Flachskamm, C., Eren, N., Kimura, M., & Chen, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-51375-7 · Cited by 30
Neuronal hypertrophy dampens neuronal intrinsic excitability and stress responsiveness during chronic stress
Matovic, S., Ichiyama, A., Igarashi, H., Salter, E. W., Sunstrum, J. K., Wang, X. F., Henry, M. S., Kuebler, E. S., Vernoux, N., Martínez-Trujillo, J., et al. (2020) · The Journal of Physiology · doi:10.1113/jp279666 · Cited by 25
Unconscious psychological treatments for physiological survival circuits
Taschereau‐Dumouchel, V., Liu, K., & Lau, H. C. (2018) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2018.04.010 · Cited by 26
Neural mechanisms of comforting: Prosocial touch and stress buffering
Lim, K. Y., & Hong, W. (2023) · Hormones and Behavior · doi:10.1016/j.yhbeh.2023.105391 · Cited by 30
Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders
Zhang, S., Zhang, Y., Shi, D., & Wang, Z. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01173-6 · Cited by 29
Social modulation of fear: Facilitation vs buffering
Morozov, A., & Ito, W. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12491 · Cited by 32
Social Transmission and Buffering of Hippocampal Metaplasticity after Stress in Mice
Lee, I., Yu, T.-H., Liu, W., & Hsu, K. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1751-20.2020 · Cited by 29
Analysis of behavioral flow resolves latent phenotypes
von Ziegler, L., Roessler, F. K., Sturman, O., Waag, R., Privitera, M., Duss, S. N., O’Connor, E. C., & Bohacek, J. (2024) · Nature Methods · doi:10.1038/s41592-024-02500-6 · Cited by 31
Translating the Transcriptome: Sex Differences in the Mechanisms of Depression and Stress, Revisited
Rainville, J. R., Lipuma, T., & Hodes, G. E. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.02.003 · Cited by 25
Butterflies in the gut: the interplay between intestinal microbiota and stress
Lai, T.-T., Liou, C.-W., Tsai, Y.-H., Lin, Y.-Y., & Wu, W. (2023) · Journal of Biomedical Science · doi:10.1186/s12929-023-00984-6 · Cited by 26
The role of the endocannabinoid system as a therapeutic target for autism spectrum disorder: Lessons from behavioral studies on mouse models
Pietropaolo, S., & Marsicano, G. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.11.031 · Cited by 23
The Dark Side of Empathy: The Role of Excessive Affective Empathy in Mental Health Disorders
Huang, C., Wu, Z., Sha, S., Liu, C., Yang, L., Jiang, P., Zhang, H., & Yang, C. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.12.020 · Cited by 30
The paraventricular nucleus of the hypothalamus: a key node in the control of behavioural states
Iremonger, K. J., & Power, E. M. (2025) · The Journal of Physiology · doi:10.1113/jp288366 · Cited by 35
Dual circuits originating from the ventral hippocampus independently facilitate affective empathy
Peng, S., Yang, X., Meng, S., Liu, F., Lv, Y., Yang, H., Kong, Y., Xie, W., & Li, M. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114277 · Cited by 22
Insular cortex modulates social avoidance of sick rats
Rieger, N. S., Worley, N. B., Ng, A. J., & Christianson, J. P. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113541 · Cited by 21
Olfactory bulb astrocytes link social transmission of stress to cognitive adaptation in male mice
Gómez-Sotres, P., Skupio, U., Tor, T. D., Julio‐Kalajzić, F., Cannich, A., Gisquet, D., Río, I. B., Drago, F., Puente, N., Grandes, P., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-51416-4 · Cited by 21
Chronic alcohol disrupts hypothalamic responses to stress by modifying CRF and NMDA receptor function
Marty, V. N., Mulpuri, Y., Munier, J. J., & Spigelman, I. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.107991 · Cited by 25
Sex-Specific Vasopressin Signaling Buffers Stress-Dependent Synaptic Changes in Female Mice
Loewen, S. P., Baimoukhametova, D. V., & Bains, J. S. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1026-20.2020 · Cited by 22
Social incentivization of instrumental choice in mice requires amygdala-prelimbic cortex-nucleus accumbens connectivity
Kietzman, H. W., Trinoskey-Rice, G., Blumenthal, S. A., Guo, J., & Gourley, S. L. (2022) · Nature Communications · doi:10.1038/s41467-022-32388-9 · Cited by 21
Female dominance hierarchies influence responses to psychosocial stressors
Smith-Osborne, L., Duong, A., Resendez, A., Palme, R., & Fadok, J. P. (2023) · Current Biology · doi:10.1016/j.cub.2023.03.020 · Cited by 19
Enhancing cognition through pharmacological and environmental interventions: Examples from preclinical models of neurodevelopmental disorders
Morè, L., Lauterborn, J. C., Papaleo, F., & Brambilla, R. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.02.003 · Cited by 20
Hypothalamic CRH neurons represent physiological memory of positive and negative experience
Füzesi, T., Rasiah, N. P., Rosenegger, D. G., Rojas‐Carvajal, M., Chomiak, T., Daviu, N., Molina, L. A., Simone, K., Sterley, T.-L., Nicola, W., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-44163-5 · Cited by 21
Concurrent stress modulates the acute and post-acute effects of psilocybin in a sex-dependent manner
Farinha‐Ferreira, M., Miranda‐Lourenço, C., Galipeau, C., Lenkei, Z., & Sebastião, A. M. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110280 · Cited by 20
Should I Stay or Should I Go? CRHPVN Neurons Gate State Transitions in Stress-Related Behaviors
Daviu, N., & Bains, J. S. (2021) · Endocrinology · doi:10.1210/endocr/bqab061 · Cited by 16
Physiological and behavioral responses to observing a sibling experience a direct stressor in prairie voles
Wardwell, J., Watanasriyakul, W. T., Normann, M. C., Akinbo, O. I., McNeal, N., Ciosek, S., Cox, M., Holzapfel, N., Sujet, S., & Grippo, A. J. (2020) · Stress · doi:10.1080/10253890.2020.1724950 · Cited by 16
Behavioral, neurochemical, and neuroimmune changes associated with social buffering and stress contagion
Chun, E. K., Donovan, M., Liu, Y., & Wang, Z. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100427 · Cited by 18
Distinct ACC Neural Mechanisms Underlie Authentic and Transmitted Anxiety Induced by Maternal Separation in Mice
Jiang, J., Tan, S., Feng, X., Peng, Y., Long, C., & Yang, L. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0558-23.2023 · Cited by 19
How classmates' stress affects student's quality of motivation
Raufelder, D., Lazarides, R., & Lätsch, A. (2018) · Stress and Health · doi:10.1002/smi.2832 · Cited by 17
Chronic predator stress in female mice reduces primordial follicle numbers: implications for the role of ghrelin
Natale, M. R. D., Soch, A., Ziko, I., Luca, S. N. D., Spencer, S. J., & Sominsky, L. (2019) · Journal of Endocrinology · doi:10.1530/joe-19-0109 · Cited by 16
Prelimbic cortex glucocorticoid receptors regulate the stress-mediated inhibition of pain contagion in male mice
Lidhar, N. K., Darvish-Ghane, S., Sivaselvachandran, S., Khan, S., Wasif, F., Turner, H., Sivaselvachandran, M., Fournier, N. M., & Martin, L. J. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-00912-4 · Cited by 16
Disruption of tonic endocannabinoid signalling triggers cellular, behavioural and neuroendocrine responses consistent with a stress response
Petrie, G. N., Balsevich, G., Füzesi, T., Aukema, R. J., Driever, W. P. F., van der Stelt, M., Bains, J. S., & Hill, M. N. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16198 · Cited by 19
Self-experience of a negative event alters responses to others in similar states through prefrontal cortex CRF mechanisms
Maltese, F., Pacinelli, G., Monai, A., Bernardi, F., Capaz, A. M., Niello, M., Walle, R., de León-Reyes, N. S., Managò, F., Leroy, F., et al. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01816-y · Cited by 24
A Systematic Review and Meta‐Analysis of the Effects of Couple‐Based Dyadic Intervention on the Psychological Distress of Cancer Patients and Their Partners
Sun, Q., Xu, P., Li, L., Wang, Z., Chen, Y., Wen, C., Wu, Z., & Peng, J. (2025) · Journal of Clinical Nursing · doi:10.1111/jocn.17677 · Cited by 16
Plasticity of intrinsic excitability across the estrous cycle in hypothalamic CRH neurons
Power, E. M., & Iremonger, K. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-96341-4 · Cited by 16
Socially Transferred Stress Experience Modulates Social Affective Behaviors in Rats
Toyoshima, M., Okuda, E., Hasegawa, N., Kaseda, K., & Yamada, K. (2022) · Neuroscience · doi:10.1016/j.neuroscience.2022.08.022 · Cited by 16
Behavioral Modulation by Social Experiences in Rodent Models
Morozov, A. (2018) · Current Protocols in Neuroscience · doi:10.1002/cpns.50 · Cited by 12
The same stress has divergent effects on social versus asocial manifestations of anxiety-like behavior over time
Saxena, K., Chakraborty, P., & Chattarji, S. (2020) · Stress · doi:10.1080/10253890.2020.1855421 · Cited by 13
Insidious Transmission of a Stress-Related Neuroadaptation
Steger, J. S., Land, B. B., Lemos, J. C., Chavkin, C., & Phillips, P. E. M. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.564054 · Cited by 12
Social buffering of human fear is shaped by gender, social concern, and the presence of real vs virtual agents
Qi, Y., Bruch, D., Krop, P., Herrmann, M. J., Latoschik, M. E., Deckert, J., & Hein, G. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01761-5 · Cited by 18
Oxytocin modulation in the medial prefrontal cortex of pair-exposed rats during fear conditioning
Jang, M., Jung, T., Jeong, Y., Byun, Y., & Noh, J. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105752 · Cited by 13
Oxytocin signaling regulates maternally directed behavior during early life
Zelmanoff, D. D., Bornstein, R., Kaufman, M., Dine, J., Wietek, J., Litvin, A., Abraham, S., Cohen, S., Atzmon, A., Porat, I., et al. (2025) · Science · doi:10.1126/science.ado5609 · Cited by 13
Early life adversity reduces affiliative behavior with a stressed cagemate and leads to sex-specific alterations in corticosterone responses in adult mice
Breton, J. M., Cort, Z., Demaestri, C., Critz, M., Nevins, S., Downend, K., Ofray, D., Romeo, R. D., & Bath, K. G. (2024) · Hormones and Behavior · doi:10.1016/j.yhbeh.2023.105464 · Cited by 11
Social environment improves the cytokine profile and lymphoproliferative response in chronologically old and prematurely aging mice
Garrido, A., & la Fuente, M. D. (2022) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2022.111692 · Cited by 11
Stress in the social environment: behavioural and social consequences of stress transmission in bird flocks
Brandl, H. B., & Farine, D. R. (2024) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2024.1961 · Cited by 9
Prior stress experience modulates social preference for stressed conspecifics in male rats
Toyoshima, M., Mitsui, K., & Yamada, K. (2021) · Neuroscience Letters · doi:10.1016/j.neulet.2021.136253 · Cited by 11
State-dependent activity dynamics of hypothalamic stress effector neurons
Ichiyama, A., Mestern, S., Benigno, G., Scott, K. E., Allman, B. L., Muller, L., & Inoue, W. (2022) · eLife · doi:10.7554/elife.76832 · Cited by 12
Serotonin modulates social responses to stressed conspecifics via insular 5-HT 2C receptors in rat
Ng, A. J., Vincelette, L. K., Li, J., Brady, B. H., & Christianson, J. P. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109598 · Cited by 9
Impact and Role of Hypothalamic Corticotropin Releasing Hormone Neurons in Withdrawal from Chronic Alcohol Consumption in Female and Male Mice
Neira, S., Lee, S., Hassanein, L. A., Sides, T. R., D’Ambrosio, S., Boyt, K. M., Bains, J. S., & Kash, T. L. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.1153-23.2023 · Cited by 9
Aggression experience and observation drive shared behavioural and neural changes
Iravedra-García, J. M., Guthman, E. M., Tsin, D., Cherepanova, P., Cuturela, L., Ocasio-Arce, E. J., Pillow, J. W., & Falkner, A. L. (2026) · Nature · doi:10.1038/s41586-026-11217-9

Authors: Sterley, T.-L., Baimoukhametova, D., Füzesi, T., Zurek, A. A., Daviu, N., Rasiah, N. P., Rosenegger, D., & Bains, J. S.
Affiliations: University of Calgary (CA)
Corresponding author: Bains, Jaideep S.
ORCID: Sterley, Toni-Lee
Füzesi, Tamás
Zurek, Agnieszka A.
Rasiah, Neilen P.
Bains, Jaideep S.
Venue: Nature Neuroscience
Publisher: Springer Science and Business Media LLC
Published: 2018-01-08
Volume: 21
Issue: 3
Pages: 393-403
ISSN: 1097-6256 (ISSN-L)
1546-1726
DOI: 10.1038/s41593-017-0044-6
OpenAlex: W2778525502
Cited by: 179
References: 46
Citations by year: 2026: 14 · 2025: 25 · 2024: 25 · 2023: 25 · 2022: 20 · 2021: 20 · 2020: 17 · 2019: 18 · 2018: 15
FWCI: 7.44
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (unspecified)
Locations: Nature Neuroscience (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords: metaplasticity, glutamatergic synapses, paraventricular nucleus, corticotropin-releasing hormone neurons, alarm pheromone, stress buffering, social interaction, female mice
MeSH terms: CRF Receptor, Type 1, Animals, Corticotropin-Releasing Hormone, Female, Glutamates, Male, Neuronal Plasticity, Paraventricular Hypothalamic Nucleus, Pheromones, Sex Characteristics, Social Behavior, Stress, Psychological, Synapses, Receptors, Corticotropin-Releasing Hormone, Patch-Clamp Techniques, Mice, Optogenetics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Social transmission and buffering of synaptic changes after stress

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks