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Inflammatory Bowel Disease and Parkinson’s Disease: A Nationwide Swedish Cohort Study

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Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis

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Distinct inflammatory phenotypes of microglia and monocyte‐derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology

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Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

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Peripheral monocytes are functionally altered and invade the CNS in ALS patients

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Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death

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Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis

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C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

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PERIPHERAL ADMINISTRATION OF LIPOPOLYSACCHARIDE INDUCES ACTIVATION OF MICROGLIAL CELLS IN RAT BRAIN**This is one of eight original manuscripts on the subject “microglia”. Dr Peter Gebicke-Haerter (Dept. Psychiatry, University of Freiburg, Germany) acted as organiser and executive editor in the refereeing of these articles.

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Evidences for vagus nerve in maintenance of immune balance and transmission of immune information from gut to brain in STM-infected rats

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NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy

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Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS

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Cytotoxic CD8 + T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons

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Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects

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Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin‐1β in neurodegeneration

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Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis

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Peripheral proinflammatory Th1/Th17 immune cell shift is linked to disease severity in amyotrophic lateral sclerosis

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Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival

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Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy

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The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis

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Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model

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Absence of Tumor Necrosis Factor-α Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutations

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Identification of potential blood biomarkers for early diagnosis of Alzheimer’s disease through RNA sequencing analysis

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Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture

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Immune responses in the Parkinson's disease brain

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Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer’s disease

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Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function

Alam, M. M., Yang, D., Li, X., Liu, J., Back, T. C., Trivett, A. L., Karim, B. O., Barbut, D., ZASLOFF, M. A., & Oppenheim, J. J. (2022) · Cell Reports · doi:10.1016/j.celrep.2021.110090 · Cited by 94 · see citing works

Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial

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LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease

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Evidence for mast cells contributing to neuromuscular pathology in an inherited model of ALS

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T helper-17 activation dominates the immunologic milieu of both amyotrophic lateral sclerosis and progressive multiple sclerosis

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Protective and Regenerative Roles of T Cells in Central Nervous System Disorders

Evans, F., Dittmer, M., de la Fuente, A. G., & Fitzgerald, D. C. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02171 · Cited by 76 · see citing works

Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL‐34, and SCF in amyotrophic lateral sclerosis

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Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis

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Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model

Reed-Geaghan, E. G., Croxford, A. L., Becher, B., & Landreth, G. E. (2020) · Journal of Experimental Medicine · doi:10.1084/jem.20191374 · Cited by 72 · see citing works

Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality

Marchlik, E., Thakker, P., Carlson, T. J., Jiang, Z., RYAN, M. S., Marušić, S., Goutagny, N., Kuang, W., Askew, G. R., Roberts, V., et al. (2010) · Journal of Leukocyte Biology · doi:10.1189/jlb.0210071 · Cited by 70 · see citing works

Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes

Parillaud, V. R., Lornet, G., Monnet, Y., Privat, A., Haddad, A. T., Brochard, V., Bekaert, A., de Chanville, C. B., Hirsch, E., Combadière, C., et al. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-017-0830-9 · Cited by 68 · see citing works

Long-term survival analysis of masitinib in amyotrophic lateral sclerosis

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NK cells associate with ALS in a sex- and age-dependent manner

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Counteracting roles of MHCI and CD8+ T cells in the peripheral and central nervous system of ALS SOD1G93A mice

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Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

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Are Circulating Cytokines Reliable Biomarkers for Amyotrophic Lateral Sclerosis?

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Increased activation ability of monocytes from ALS patients

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Correlation between leukocyte phenotypes and prognosis of amyotrophic lateral sclerosis

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Effects of Chronic Masitinib Treatment in APPswe/PSEN1dE9 Transgenic Mice Modeling Alzheimer’s Disease

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Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells

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Development of ALS-like disease in SOD-1 mice deficient of B lymphocytes

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Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice

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Decreased Expression of Cathepsin D in Monocytes is Related to the Defective Degradation of Amyloid-β in Alzheimer's Disease

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Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS

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Associations between autoimmune diseases and amyotrophic lateral sclerosis: a register-based study

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Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation

Han, Y., Ripley, B., Serada, S., Naka, T., & Fujimoto, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153399 · Cited by 24 · see citing works

Circulating Cytokines Could Not Be Good Prognostic Biomarkers in a Mouse Model of Amyotrophic Lateral Sclerosis

Moreno‐Martínez, L., de la Torre, M., Toivonen, J. M., Zaragoza, P., García‐Redondo, A., Calvo, A. C., & Osta, R. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00801 · Cited by 24 · see citing works

The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS

Kovacs, M., Alamón, C., Maciel, C., Varela, V., Ibarburu, S., Tarragó, L., King, P. H., Si, Y., Kwon, Y., Hermine, O., et al. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01241-3 · Cited by 19 · see citing works

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

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Alzheimer’s Disease Research Using Human Microglia

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Differential Regional Vulnerability of the Brain to Mild Neuroinflammation Induced by Systemic LPS Treatment in Mice

Jung, H., Lee, H., Kim, D., Cheong, E., Hyun, Y., Yu, J., & Um, J. W. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s362006 · Cited by 31 · see citing works

Deciphering the contributions of neuroinflammation to neurodegeneration: lessons from antibody-mediated encephalitis and coronavirus disease 2019

Shir, D., & Day, G. S. (2022) · Current Opinion in Neurology · doi:10.1097/wco.0000000000001033 · Cited by 13 · see citing works

Recent advances in the mechanisms of neuroinflammation and their roles in neurodegeneration

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A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

Voet, S., Mc Guire, C., Hagemeyer, N., Martens, A., Schroeder, A., Wieghofer, P., Daems, C., Staszewski, O., Vande Walle, L., Jordao, M. J. C., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04376-5 · Cited by 227 · see citing works