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Cited by 147Food composition and propertiesDiet, Metabolism, and DiseaseDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

Diets high and low in glycemic index versus high monounsaturated fat diets: effects on glucose and lipid metabolism in NIDDM

Luscombe, ND, Noakes, M, Clifton, PM·1999·European Journal of Clinical Nutrition
DOI 10.1038/sj.ejcn.1600779
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Abstract

Objective To examine the relative effects of high and low glycemic index (GI) carbohydrates, and monounsaturated fats on blood glucose and lipid metabolism in NIDDM subjects.Subjects Fourteen male and seven female variably controlled NIDDM subjects recruited by advertisement.Setting Free living outpatients.Research design A repeated measures, within-subject design was used such that each subject consumed three diets: (a) a high-GI diet (53% CHO -21% fat, 63 GI units (glucose= 100)); (b) a low-GI diet (51% CHO -23% fat, 43 GI units); and (c) a high-mono high-GI diet (42% CHO -35% fat, 59 GI units) in random order and cross-over fashion for four weeks. Approximately 45% energy was provided as key foods which differed in published GI values and specifically excluded legumes. Dietary fibre intake was > 30 g/d on each diet. At the end of each dietary intervention, we measured fasting plasma lipids, glucose, insulin, total glycated plasma protein, fructosamine, LDL and HDL particle size as well as 24 h urinary excretion of glucose and C-peptide.Results HDL-cholesterol was higher on the low-GI and high-mono high-GI diets compared to the high-GI diet (P < 0.05 for overall diet effect). There were no other significant differences in metabolic control between diets, even when adjusted for BMI, glucose control or gender. Body weight and saturated fat intake remained stable between dietary interventions.Conclusion High-mono high-GI and high-CHO, low-GI diets are superior to high-CHO, high-GI diets with respect to HDL metabolism but no effect was noted on glucose metabolism in variably controlled NIDDM subjects.

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Crossref · 10.1038/sj.ejcn.1600779

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Metadata

Authors
Luscombe, N., Noakes, M., & Clifton, P.
Affiliations
Commonwealth Scientific and Industrial Research Organisation (AU)
ORCID
Noakes, M
Venue
European Journal of Clinical Nutrition
Publisher
Springer Science and Business Media LLC
Published
1999-06-01
Volume
53
Issue
6
Pages
473-478
ISSN
  • 0954-3007 (ISSN-L)
  • 1476-5640
DOI
10.1038/sj.ejcn.1600779
OpenAlex
W1993715747
Cited by
147
References
35
Citations by year
2023: 1 · 2022: 1 · 2021: 2 · 2019: 2 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 2 · 2014: 5 · 2013: 1 · 2012: 5
FWCI
8.84
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • European Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
glycemic index, monounsaturated fatty acids, type 2 diabetes, glucose metabolism, lipid metabolism, HDL cholesterol, insulin, fructosamine, LDL particle size, dietary intervention, dietary fiber
MeSH terms
Analysis of Variance, Blood Glucose, Body Weight, Cholesterol, Diabetes Mellitus, Type 2, Dietary Carbohydrates, Dietary Fats, Fatty Acids, Monounsaturated, Female, Humans, Male, Middle Aged, Triglycerides, Cross-Over Studies

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