Glycemic index of foods: a physiological basis for carbohydrate exchange
Abstract
The determine the effect of different foods on the blood glucose, 62 commonly eaten foods and sugars were fed individually to groups of 5 to 10 healthy fasting volunteers. Blood glucose levels were measured over 2 h, and expressed as a percentage of the area under the glucose response curve when the same amount of carbohydrate was taken as glucose. The largest rises were seen with vegetables (70 +/- 5%), followed by breakfast cereals (65 +/- 5%), cereals and biscuits (60 +/- 3%), fruit (50 +/- 5%), dairy products (35 +/- 1%), and dried legumes (31 +/- 3%). A significant negative relationship was seen between fat (p less than 0.01) and protein (p less than 0.001) and postprandial glucose rise but not with fiber or sugar content.
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Accumulating evidence indicates that diets containing a preponderance of low-GI foods induce modest to clinically important benefits in the intermediate term as shown by intervention studies.
“there is accumulating evidence (Brand-Miller, 2004) that diets containing a preponderance of foods that elicit low glycaemic responses ('low-GI foods or diets'), as originally defined by Jenkins et al. (1981) induce modest to clinically important benefits in the intermediate term as shown by intervention studies”
From Glycaemic index methodology (2005) · cites this paper as Jenkins et al. (1981)
The glycaemic index concept was introduced to classify carbohydrate-rich foods by their effect on blood glucose after a meal.
“The glycaemic index (GI) concept was originally introduced as a means of classifying different sources of carbohydrate (CHO) and CHO-rich foods in the diet, according to their effect on postprandial glycaemia (Jenkins et al. 1981).”
From Glycaemic index methodology (2005) · cites this paper as Jenkins et al. 1981
Polyols have a low glycaemic index.
“Polyol-containing foods are potentially of interest to the diabetic because polyols have a low glycaemic index (Brunzell, 1978; Jenkins et al. 1981; Pelletier et al. 1994).”
From Polyols in confectionery: the route to sugar-free, reduced sugar and reduced calorie confectionery (2001) · cites this paper as Jenkins et al. 1981
Pasta generally has a lower glycemic impact than many other refined starch sources because of its compact structure and slower starch hydrolysis.
“Pasta is commonly consumed, is practical to standardize, and generally has a lower glycemic impact than many other refined starch sources because of its compact structure and slower starch hydrolysis [18,19].”
From Does Resistant Starch Formed by Cooling Pasta Decrease the Postprandial Glycemic Response in Type 1 Diabetes? A Randomized Single-Blind Crossover Study (2026) · cites this paper as [18]
Pasta typically induces a slower glycemic rise than many rice preparations because of its compact structure and slower starch hydrolysis.
“First, pasta typically induces a slower glycemic rise than many rice preparations because of its compact structure and slower starch hydrolysis [18,19].”
From Does Resistant Starch Formed by Cooling Pasta Decrease the Postprandial Glycemic Response in Type 1 Diabetes? A Randomized Single-Blind Crossover Study (2026) · cites this paper as [18]
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BackgroundSwallowing food without chewing; a simple way to reduce postprandial glycaemia
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Kendall, C. W. C., Josse, A. R., Esfahani, A., & Jenkins, D. J. A. (2010) · British Journal of Nutrition · doi:10.1017/s0007114510001546 · Cited by 127 · see citing works
Self-citationNon-pharmacological Treatment Options in the Management of Diabetes Mellitus
Raveendran, A. V. (2018) · European Endocrinology · doi:10.17925/ee.2018.14.2.31 · Cited by 122 · see citing works
Dong, J.-Y., Zhang, L., Zhang, Y.-H., & Qin, L.-Q. (2011) · British Journal Of Nutrition · doi:10.1017/s000711451100540x · Cited by 124 · see citing works
Stevenson, E. J., Williams, C., Mash, L. E., Phillips, B., & Nute, M. L. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.2.354 · Cited by 121 · see citing works
Low glycaemic index diets for coronary heart disease
Kelly, S. A., Frost, G., Whittaker, V., & Summerbell, C. D. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004467.pub2 · Cited by 122 · see citing works
Metabolic effects of low glycaemic index diets
Radulian, G., Rusu, E., Dragomir, A., & Posea, M. (2009) · Nutrition Journal · doi:10.1186/1475-2891-8-5 · Cited by 119 · see citing works
Jenkins, D. J. A., Willett, W. C., Yusuf, S., Hu, F. B., Glenn, A. J., Liu, S., Mente, A., Miller, V., Bangdiwala, S. I., Gerstein, H. C., et al. (2024) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(23)00344-3 · Cited by 117 · see citing works
Self-citationDietary glycemic index, glycemic load, and risk of cancer: a prospective cohort study
George, S. M., Mayne, S. T., Leitzmann, M. F., Park, Y., Schatzkin, A., Flood, A., Hollenbeck, A., & Subar, A. F. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn347 · Cited by 111 · see citing works
Meng, H., Matthan, N. R., Ausman, L. M., & Lichtenstein, A. H. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.144162 · Cited by 110 · see citing works
Is glycaemic index (GI) a valid measure of carbohydrate quality?
Wolever, T. M. S. (2013) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2013.27 · Cited by 108 · see citing works
Self-citationCarbohydrate issues: type and amount
Wheeler, M. L., & Pi-Sunyer, F. X. (2008) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2008.01.024 · Cited by 105 · see citing works
Levitan, E. B., Mittleman, M. A., Håkansson, N., & Wolk, A. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.6.1521 · Cited by 100 · see citing works
Effect of meal frequency on blood glucose, insulin, and free fatty acids in NIDDM subjects
Bertelsen, J., Christiansen, C., Thomsen, C., Poulsen, P. L., Vestergaard, S., Steinov, A., Rasmussen, L. H., Rasmussen, O., & Hermansen, K. (1993) · Diabetes Care · doi:10.2337/diacare.16.1.4 · Cited by 97 · see citing works
- Authors
- Jenkins, D. J., Wolever, T. M., Taylor, R. H., Barker, H., Fielden, H., Baldwin, J. M., Bowling, A. C., Newman, H. C., Jenkins, A. L., & Goff, D. V.
- Affiliations
- University of Toronto (CA)
- Central Middlesex Hospital (GB)
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1981-03
- Volume
- 34
- Issue
- 3
- Pages
- 362-366
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2097365404
- Cited by
- 3,857
- References
- 0
- Citations by year
- 2026: 85 · 2025: 102 · 2024: 88 · 2023: 120 · 2022: 174 · 2021: 163 · 2020: 133 · 2019: 135 · 2018: 129 · 2017: 131 · 2016: 273 · 2015: 185 · 2014: 179 · 2013: 214 · 2012: 169
- FWCI
- 21.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Health Sciences › Medicine › Physiology › Diet and metabolism studies
- Keywords
- glycemic index, glycemic response, postprandial blood glucose, dietary fat, dietary protein, dietary fiber, sugar, vegetables, breakfast cereals, fruits, dairy products, Fabaceae, food composition
- MeSH terms
- Adult, Blood Glucose, Diet, Diabetic, Diet, Dietary Carbohydrates, Dietary Fats, Dietary Fiber, Dietary Proteins, Female, Food Analysis, Humans, Male, Carbohydrate Metabolism
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