The DOI matches its Crossref record; 91 of the 92 references it cites were found in a registry or an index.
The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes
Open accessAbstract
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies have demonstrated the importance of genetic factors and candidate gene association studies have identified several loci that exert small but significant effects on ADHD. To provide further clarification of reported associations and identify novel associated genes, we examined 1,038 single-nucleotide polymorphisms (SNPs) spanning 51 candidate genes involved in the regulation of neurotransmitter pathways, particularly dopamine, norepinephrine and serotonin pathways, in addition to circadian rhythm genes. Analysis used within family tests of association in a sample of 776 DSM-IV ADHD combined type cases ascertained for the International Multi-centre ADHD Gene project. We found nominal significance with one or more SNPs in 18 genes, including the two most replicated findings in the literature: DRD4 and DAT1. Gene-wide tests, adjusted for the number of SNPs analysed in each gene, identified associations with TPH2, ARRB2, SYP, DAT1, ADRB2, HES1, MAOA and PNMT. Further studies will be needed to confirm or refute the observed associations and their generalisability to other samples.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“it has been proposed that valid endophenotypes can be found at a higher rate in unaffected family members than in the general population 23,24.”
From Increased neural responses to reward in adolescents and young adults with attention-deficit/hyperactivity disorder and their unaffected siblings (2015) · cites this paper as [24]
Experimental — accuracy not yet measuredIn the citing paper
“Brookes et al. (2006) in a genome-wide study provide speculative evidence that polymorphisms in PER 2 may be associated with ADHD in children, but the association was not significant at the study-wide or genome-wide level”
From A systematic review of circadian function, chronotype and chronotherapy in attention deficit hyperactivity disorder (2017) · cites this paper as Brookes et al. (2006)
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Strengths and Difficulties Questionnaire: A research note
Goodman, R. (1997) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1997.tb01545.x · Cited by 14,908
The Structure of Haplotype Blocks in the Human Genome
Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science · doi:10.1126/science.1069424 · Cited by 5,863
A haplotype map of the human genome
The International HapMap Consortium (2005) · Nature · doi:10.1038/nature04226 · Cited by 5,858
Molecular genetics of attention-deficit/hyperactivity disorder
Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., & Sklar, P. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.024 · Cited by 2,357
Self-citationNeuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
Castellanos, F. X., & Tannock, R. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn896 · Cited by 1,827
Attention-deficit hyperactivity disorder
Biederman, J., & Faraone, S. V. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66915-2 · Cited by 1,463
Self-citationThe British Child and Adolescent Mental Health Survey 1999: The Prevalence of DSM-IV Disorders
FORD, T., GOODMAN, R., & MELTZER, H. (2003) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200310000-00011 · Cited by 1,227
Role of Serotonin in the Paradoxical Calming Effect of Psychostimulants on Hyperactivity
Gainetdinov, R. R., Wetsel, W. C., Jones, S. R., Levin, E. D., Jaber, M., & Caron, M. G. (1999) · Science · doi:10.1126/science.283.5400.397 · Cited by 885
European clinical guidelines for hyperkinetic disorder ? first upgrade
Taylor, E., D�pfner, M., Sergeant, J., Asherson, P., Banaschewski, T., Buitelaar, J., Coghill, D., Danckaerts, M., Rothenberger, A., Sonuga-Barke, E., et al. (2004) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-004-1002-x · Cited by 682
Self-citationThe Future of Association Studies: Gene-Based Analysis and Replication
Neale, B. M., & Sham, P. C. (2004) · The American Journal of Human Genetics · doi:10.1086/423901 · Cited by 605
Self-citationLi, D., Sham, P. C., Owen, M. J., & He, L. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl152 · Cited by 602
Self-citationThe Dopamine D2 Receptor Locus as a Modifying Gene in Neuropsychiatric Disorders
Comings, D. E. (1991) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1991.03470130073032 · Cited by 587
Daly, G., Hawi, Z., Fitzgerald, M., & Gill, M. (1999) · Molecular Psychiatry · doi:10.1038/sj.mp.4000510 · Cited by 377
Self-citationKessler, R. C., Adler, L., Ames, M., Barkley, R. A., Birnbaum, H., Greenberg, P., Johnston, J. A., Spencer, T., & ??st??n, T. B. (2005) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000166863.33541.39 · Cited by 335
Winstanley, C. A., Theobald, D. E. H., Dalley, J. W., & Robbins, T. W. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300610 · Cited by 331
Brookes, K. J., Mill, J. S., Guindalini, C., Curran, S. R., Xu, X., Knight, J., Chen, C., Huang, Y., Sethna, V., Taylor, E. A., et al. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.1.74 · Cited by 320
Self-citationConduct Disorder and Hyperactivity: I
Taylor, E., Everitt, B. J., Ruttermd, M. L., Thorley, G., Schachar, R. J., & Wieselberg, M. (1986) · The British Journal of Psychiatry · doi:10.1192/bjp.149.6.760 · Cited by 297
Self-citationA Genomewide Scan for Loci Involved in Attention-Deficit/Hyperactivity Disorder
Fisher, S. E., Francks, C., McCracken, J. T., McGough, J. J., Marlow, A. J., MacPhie, I. L., Newbury, D. F., Crawford, L. R., Palmer, C. G. S., Woodward, J. A., et al. (2002) · The American Journal of Human Genetics · doi:10.1086/340112 · Cited by 294
A twin study of the etiology of comorbidity: attention-deficit hyperactivity disorder and dyslexia.
Gilger, J., Pennington, B., & Defries, J. (1992) · Journal of the American Academy of Child and Adolescent Psychiatry · doi:10.1097/00004583-199203000-00024 · Cited by 268
Co‐occurrence of ADHD and low IQ has genetic origins
Kuntsi, J., Eley, T. C., Taylor, A., Hughes, C., Asherson, P., Caspi, A., & Moffitt, T. E. (2004) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.20076 · Cited by 267
Self-citationBakker, S. C., Meulen, E. M. V. D., Buitelaar, J. K., Sandkuijl, L. A., Pauls, D. L., Monsuur, A. J., Slot, R. V. ‘., Minderaa, R. B., Gunning, W. B., Pearson, P. L., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/375143 · Cited by 257
Self-citationSmalley, S. L., Kustanovich, V., Minassian, S. L., Stone, J. L., Ogdie, M. N., McGough, J. J., McCracken, J. T., MacPhie, I. L., Francks, C., Fisher, S. E., et al. (2002) · The American Journal of Human Genetics · doi:10.1086/342732 · Cited by 240
Support for association between ADHD and two candidate genes: NET1 and DRD1
Bobb, A. J., Addington, A. M., Sidransky, E., Gornick, M. C., Lerch, J. P., GREENSTEIN, D. K., CLASEN, L. S., Sharp, W. S., Inoff‐Germain, G., Vrièze, F. W., et al. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30142 · Cited by 232
Barr, C., Feng, Y., Wigg, K., Bloom, S., Roberts, W., Malone, M., Schachar, R., Tannock, R., & Kennedy, J. L. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000733 · Cited by 222
Ogdie, M. N., Macphie, I. L., Minassian, S. L., Yang, M., Fisher, S. E., Francks, C., Cantor, R. M., McCracken, J. T., McGough, J. J., Nelson, S. F., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/375139 · Cited by 220
Arcos‐Burgos, M., Castellanos, F. X., Pineda, D. A., Lopera, F. J., Palacio, J. D., Palacio, L. G., Rapoport, J. L., Berg, K. A., Wilson, J., & Muenke, M. (2004) · The American Journal of Human Genetics · doi:10.1086/426154 · Cited by 211
Thapar, A., Langley, K., Fowler, T., Rice, F. J., Turic, D., Whittinger, N., Aggleton, J. P., van den Bree, M. B. M., Owen, M. J., & O’Donovan, M. C. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.11.1275 · Cited by 201
Clinical assessment and treatment of attention deficit hyperactivity disorder in adults
Asherson, P. (2005) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.5.4.525 · Cited by 195
Self-citationHawi, Z., Dring, M., Kirley, A., Foley, D., Kent, L., Craddock, N., Asherson, P., Curran, S., Gould, A., Richards, S., et al. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001048 · Cited by 175
Self-citationBrophy, K., Hawi, Z., Kirley, A., Fitzgerald, M., & Gill, M. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4001092 · Cited by 171
Self-citationMultivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder
Comings, D., Gade-Andavolu, R., Gonzalez, N., Wu, S.-J., Muhleman, D., Blake, H., Chiu, F., Wang, E., Farwell, K., Darakjy, S., et al. (2000) · Clinical Genetics · doi:10.1034/j.1399-0004.2000.580106.x · Cited by 162
A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs
Hebebrand, J., Dempfle, A., Saar, K., Thiele, H., Herpertz-Dahlmann, B., Linder, M., Kiefl, H., Remschmidt, H., Hemminger, U., Warnke, A., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001761 · Cited by 159
Walitza, S., Renner, T. J., Dempfle, A., Konrad, K., Wewetzer, C., Halbach, A., Herpertz-Dahlmann, B., Remschmidt, H., Smidt, J., Linder, M., et al. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001734 · Cited by 158
Comings, D. E., Gade‐Andavolu, R., González, N., Wu, S., Muhleman, D. R., Blake, H., Dietz, G., Saucier, G., & MacMurray, J. P. (2000) · Clinical Genetics · doi:10.1034/j.1399-0004.2000.570304.x · Cited by 154
Kent, L., Doerry, U., Hardy, E., Parmar, R., Gingell, K., Hawi, Z., Kirley, A., Lowe, N., Fitzgerald, M., Gill, M., et al. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001100 · Cited by 153
Self-citationClinical and Molecular Genetics of ADHD and Tourette Syndrome
Comings, D. E. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb05773.x · Cited by 152
Manor, I., Tyano, S., Mel, E., Eisenberg, J., Bachner-Melman, R., Kotler, M., & Ebstein, R. P. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001037 · Cited by 150
Self-citationThe serotonin 5-HT1B receptor gene and attention deficit hyperactivity disorder
Quist, J., Barr, C., Schachar, R., Roberts, W., Malone, M., Tannock, R., Basile, V., Beitchman, J., & Kennedy, J. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001244 · Cited by 148
Tryptophan Hydroxylase 2 (TPH2) gene variants associated with ADHD
Sheehan, K., Lowe, N., Kirley, A., Mullins, C., Fitzgerald, M., Gill, M., & Hawi, Z. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001698 · Cited by 141
Self-citationAssociation of Fatty Acid Desaturase Genes with Attention-Deficit/Hyperactivity Disorder
Brookes, K. J., Chen, W., Xu, X., Taylor, E. A., & Asherson, P. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.025 · Cited by 136
Self-citationOgdie, M. N., Fisher, S. E., Yang, M., Ishii, J., Francks, C., Loo, S. K., Cantor, R. M., McCracken, J. T., McGough, J. J., Smalley, S. L., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/424387 · Cited by 133
Payton, A., Holmes, J., Barrett, J. H., Hever, T., Fitzpatrick, H., Trumper, A., Harrington, R., McGuffin, P., O’Donovan, M. C., Owen, M. J., et al. (2001) · American Journal of Medical Genetics · doi:10.1002/ajmg.1407 · Cited by 124
Self-citationBiased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder
Kustanovich, V., Merriman, B., McGough, J., McCracken, J. T., Smalley, S. L., & Nelson, S. F. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001247 · Cited by 122
Hawi, Z., Lowe, N., Kirley, A., Gruenhage, F., Nöthen, M. M., Greenwood, T. A., Kelsoe, J. R., Fitzgerald, M., & Gill, M. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001290 · Cited by 120
Self-citationEssential fatty acids and mental health
Hallahan, B. P., & Garland, M. R. (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.186.4.275 · Cited by 120
Conduct Disorder and Hyperactivity: II
Taylor, E. A., Everitt, B. J., Rutter, M. L., Thorley, G., Schachar, R. J., & Wieselberg, H. M. (1986) · The British Journal of Psychiatry · doi:10.1192/bjp.149.6.768 · Cited by 115
Self-citationTodd, R. D., Lobos, E. A., Sun, L.-W., & Neuman, R. J. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001257 · Cited by 115
Roman, T., Schmitz, M. D., Polanczyk, G. V., Eizirik, M., Rohde, L. A., & Hutz, M. H. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.10194 · Cited by 115
Qian, Q., Wang, Y., Zhou, R., Li, J., Wang, B., Glatt, S., & Faraone, S. V. (2003) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.10064 · Cited by 113
Self-citationComings, D., Gade-Andavolu, R., Gonzalez, N., Blake, H., Wu, S., & MacMurray, J. P. (1999) · Clinical Genetics · doi:10.1034/j.1399-0004.1999.550304.x · Cited by 113
Smith, K. M., Daly, M. J., Fischer, M., Yiannoutsos, C. T., Bauer, L., Barkley, R. A., & NAVIA, B. A. (2003) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.20005 · Cited by 112
Association analysis of monoamine oxidase A and attention deficit hyperactivity disorder
Lawson, D. C., Turic, D., Langley, K., Pay, H. M., Govan, C. F., Norton, N., Hamshere, M. L., Owen, M. J., O'Donovan, M. C., & Thapar, A. (2003) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.10002 · Cited by 108
Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD
Mill, J. S., Richards, S., Knight, J., Curran, S. R., Taylor, E. A., & Asherson, P. J. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001482 · Cited by 104
Self-citationThe SNAP25 gene as a susceptibility gene contributing to attention-deficit hyperactivity disorder
Feng, Y., Crosbie, J., Wigg, K., Pathare, T., Ickowicz, A., Schachar, R. J., Tannock, R., Roberts, W., MALONE, M. A., Swanson, J. M., et al. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001722 · Cited by 101
Bellgrove, M. A., Hawi, Z., Lowe, N., Kirley, A., Robertson, I. H., & Gill, M. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30193 · Cited by 100
Self-citationAssociation study of a SNAP-25 microsatellite and attention deficit hyperactivity disorder.
Mill, J., Curran, S., Kent, L., Gould, A., Huckett, L., Richards, S., Taylor, E., & Asherson, P. (2002) · American journal of medical genetics · doi:10.1002/ajmg.10253 · Cited by 94
Self-citationDomschke, K., Sheehan, K., Lowe, N., Kirley, A., Mullins, C., O’Sullivan, R. J., Freitag, C., Becker, T., Conroy, J., Fitzgerald, M., et al. (2005) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30158 · Cited by 89
Self-citationCLUSTAG: hierarchical clustering and graph methods for selecting tag SNPs
Ao, S. I., Yip, K. Y.-L., Ng, M., Cheung, D. W.-L., Fong, P. Y., Melhado, I., & Sham, P. C. (2004) · Computer applications in the biosciences · doi:10.1093/bioinformatics/bti201 · Cited by 88
Self-citationThe serotonin transporter gene as a QTL for ADHD
Curran, S. R., Purcell, S., Craig, I., Asherson, P. J., & Sham, P. C. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30118 · Cited by 87
Self-citationTjon Pian Gi, C. V., Broeren, J. P. A., Starreveld, J. S., & A. Versteegh, F. G. (2003) · European Journal of Pediatrics · doi:10.1007/s00431-003-1207-x · Cited by 85
The norepinephrine transporter gene and attention‐deficit hyperactivity disorder
Barr, C. L., Kroft, J., Feng, Y., Wigg, K. G., Roberts, W., MALONE, M. A., Ickowicz, A., Schachar, R. J., Tannock, R., & Kennedy, J. L. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.10193 · Cited by 80
Burd, L., Klug, M. G., Coumbe, M. J., & Kerbeshian, J. (2003) · Journal of Child Neurology · doi:10.1177/08830738030180080101 · Cited by 78
Kent, L., Middle, F., Hawi, Z., Fitzgerald, M., Gill, M., Feehan, C., & Craddock, N. J. (2001) · Psychiatric Genetics · doi:10.1097/00041444-200103000-00007 · Cited by 71
Self-citationThe DRD2 TaqI polymorphism and symptoms of attention deficit hyperactivity disorder
Rowe, D. C., Oord, E. V. D., Stever, C., Giedinghagen, L. N., Gard, J. M. C., Cleveland, H., Gilson, M., Terris, S. T., Mohr, J., Sherman, S., et al. (1999) · Molecular Psychiatry · doi:10.1038/sj.mp.4000567 · Cited by 71
Linkage studies between attention‐deficit hyperactivity disorder and the monoamine oxidase genes
Jiang, S., Xin, R., Lin, S., Qian, Y., Tang, G., Wang, D., & Wu, X. (2001) · American Journal of Medical Genetics · doi:10.1002/ajmg.10098 · Cited by 57
Xu, X., Knight, J., Brookes, K. J., Mill, J. S., Sham, P. C., Craig, I., Taylor, E. A., & Asherson, P. J. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30160 · Cited by 55
Self-citationLowe, N., Kirley, A., Mullins, C., Fitzgerald, M., Gill, M., & Hawi, Z. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30071 · Cited by 54
Self-citationMcEvoy, B., Hawi, Z., Fitzgerald, M., & Gill, M. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.10416 · Cited by 52
Self-citationAttention deficit hyperactivity disorder and the gene for dopamine Beta-hydroxylase.
Wigg, K., Zai, G., Schachar, R., Tannock, R., Roberts, W., Malone, M., Kennedy, J., & Barr, C. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.6.1046 · Cited by 52
Feng, Y., Wigg, K. G., Makkar, R., Ickowicz, A., Pathare, T., Tannock, R., Roberts, W., MALONE, M. A., Kennedy, J. L., Schachar, R. J., et al. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30190 · Cited by 50
Serotonin 5‐HT1B receptor gene and attention deficit hyperactivity disorder in Chinese Han subjects
Li, J., Wang, Y., Zhou, R., Zhang, H., Yang, L., Wang, B., Khan, S., & Faraone, S. V. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30075 · Cited by 46
Self-citationMuglia, P., Jain, U., & Kennedy, J. L. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00438-7 · Cited by 41
No evidence for the association of DRD4 with ADHD in a Taiwanese population within-family study
Brookes, K., Xu, X.-H., Chen, C.-K., Huang, Y.-S., Wu, Y., & Asherson, P. (2005) · BMC Medical Genetics · doi:10.1186/1471-2350-6-31 · Cited by 40
Self-citationPower tools for human genetics
Kruglyak, L. (2005) · Nature Genetics · doi:10.1038/ng1205-1299 · Cited by 37
Hawi, Z., Foley, D. L., Kirley, A., McCarron, M., Fitzgerald, M., & Gill, M. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000903 · Cited by 36
Self-citationLuca, V. D., Muglia, P., Jain, U., & Kennedy, J. L. (2003) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.20075 · Cited by 35
Xu, X., Mill, J. S., Chen, C., Brookes, K. J., Taylor, E. A., & Asherson, P. J. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30203 · Cited by 34
Self-citationInkster, B., Muglia, P., Jain, U., & Kennedy, J. (2004) · Psychiatric Genetics · doi:10.1097/01.ypg.0000107932.32051.1c · Cited by 31
DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters
Brookes, K. J., Knight, J., Xu, X., & Asherson, P. J. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30216 · Cited by 30
Self-citationZhang, H.-B., Wang, Y., Li, J., Wang, B., & Yang, L. (2005) · PubMed · Cited by 27
West, A., Langley, K., Hamshere, M. L., Kent, L., Craddock, N. J., Owen, M. J., O’Donovan, M. C., & Thapar, A. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001129 · Cited by 20
Todd, R. D., & Lobos, E. A. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.1619 · Cited by 20
Situational versus pervasive hyperactivity in a community sample
Ho, T. P., Luk, E., Leung, P. W. L., Taylor, E. A., Lieh‐Mak, F., & Bacon‐Shone, J. (1996) · Psychological Medicine · doi:10.1017/s003329170003470x · Cited by 20
Self-citationSouery, D., Lipp, O., Rivelli, S. K., Massat, I., Serretti, A., Cavallini, M. C., Ackenheil, M., Adolfsson, R., Aschauer, H. N., Blackwood, D., et al. (1999) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19991015)88:5 · Cited by 19
Self-citationHuang, Y., Lin, S., Wu, Y., Chao, C., & Chen, C. (2003) · PubMed · Cited by 15
Li, J., Wang, Y., Qian, Q., Wang, B., & Zhou, R. (2002) · PubMed · Cited by 13
Séi, H., Sano, A., Oishi, K., Fujihara, H., Kobayashi, H., Ishida, N., & Morita, Y. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00909-0 · Cited by 12
Zhang, H.-B., Wang, Y., Li, J., Wang, B., & Yang, L. (2004) · PubMed · Cited by 10
Li, J., Wang, Y. F., Zhou, R., Zhang, H.-B., Wang, B., & Wang, B. (2004) · PubMed · Cited by 7
Donnelly, S. L., Wolpert, C. M., Menold, M. M., Bass, M. P., Gilbert, J. R., Cuccaro, M. L., Delong, G. R., & Pericak-Vance, M. A. (2000) · American Journal of Medical Genetics · doi:10.1002/1096-8628(20000612)96:3
Flagged first, then by citations
1 of the 92 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- Asherson P . IMAGE consortium. Attention-deficit hyperactivity disorder in the post-genomic era. Eur Child Adolesc Psychiatry 2004; 13 (Suppl 1): 150–170.
- Todd RD, Lobos EA, Sun LW, Neuman RJ . Mutational analysis of the nicotinic acetylcholine receptor alpha 4 subunit gene in attention deficit/hyperactivity disorder: evidence for association of an intronic polymorphism with attention problems. Mol Psychiatry 2003; 8: 103–108. · DOI
- Todd RD, Lobos EA, Sun LW, Neuman RJ . Mutational analysis of the nicotinic acetylcholine receptor alpha 4 subunit gene in attention deficit/hyperactivity disorder: evidence for association of an intronic polymorphism with attention problems. Mol Psychiatry 2003; 8: 103–108. · DOI
- Barr CL, Wigg KG, Bloom S, Schachar R, Tannock R, Roberts W et al. Further evidence from haplotype analysis for linkage of the dopamine D4 receptor gene and attention-deficit hyperactivity disorder. Am J Med Genet 2000; 96: 262–267. · DOI · Paper page
Cited by
Sorted by citations
Mindfulness: Theoretical Foundations and Evidence for its Salutary Effects
Brown, K. W., Ryan, R. M., & Creswell, J. D. (2007) · Psychological Inquiry · doi:10.1080/10478400701598298 · Cited by 3,654
Molecular genetics of attention-deficit/hyperactivity disorder
Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., & Sklar, P. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.024 · Cited by 2,357
Self-citationGenetics of attention deficit hyperactivity disorder
Faraone, S. V., & Larsson, H. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0070-0 · Cited by 1,338
Self-citationEmotion-related self-regulation and its relation to children's maladjustment
Eisenberg, N., Spinrad, T. L., & Eggum, N. D. (2010) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.121208.131208 · Cited by 1,259
Candidate gene studies of ADHD: a meta-analytic review
Gizer, I. R., Ficks, C., & Waldman, I. D. (2009) · Human Genetics · doi:10.1007/s00439-009-0694-x · Cited by 1,020
Metadata
- Authors
- Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., Aneey, R., Franke, B., Gill, M., Ebstein, R., Buitelaar, J., Sham, P., Campbell, D., Knight, J., Andreou, P., Altink, M., Arnold, R., Boer, F., Buschgens, C., Butler, L., Christiansen, H., Feldman, L., Fleischman, K., Fliers, E., Howe-Forbes, R., Goldfarb, A., Heise, A., Gabriëls, I., Korn-Lubetzki, I., Marco, R., Medad, S., Minderaa, R., Mulas, F., Müller, U., Mulligan, A., Rabin, K., Rommelse, N., Sethna, V, Sorohan, J., Uebel, H., Psychogiou, L., Weeks, A., Barrett, R., Craig, I., Banaschewski, T., Sonuga-Barke, E., Eisenberg, J., Kuntsi, J., Manor, I., McGuffin, P., Miranda, A., Oades, R. D., Plomin, R., Roeyers, H., Rothenberger, A., Sergeant, J., Steinhausen, H.-C., Taylor, E., Thompson, M., Faraone, S. V., Asherson, P., & Johansson, L.
- Affiliations
- St. James's Hospital (IE)
- Radboud University Nijmegen (NL)
- Herzog Hospital (IL)
- Geha Mental Health Center (IL)
- University of Göttingen (DE)
- Ghent University (BE)
- Shaare Zedek Medical Center (IL)
- Universitat de València (ES)
- University Medical Center Groningen (NL)
- University of Zurich (CH)
- Vrije Universiteit Amsterdam (NL)
- University of Southampton (GB)
- SUNY Upstate Medical University (US)
- Corresponding author
- Asherson, P
- ORCID
- Venue
- Molecular Psychiatry
- Published
- 2006-08-08
- Volume
- 11
- Issue
- 10
- Pages
- 934-953
- ISSN
- 1359-4184 (ISSN-L)
- 1476-5578
- OpenAlex
- W2149164700
- Cited by
- 533
- References
- 92
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 9 · 2023: 6 · 2022: 11 · 2021: 9 · 2020: 13 · 2019: 13 · 2018: 14 · 2017: 19 · 2016: 35 · 2015: 27 · 2014: 34 · 2013: 26 · 2012: 38
- FWCI
- 36.39
- Type
- journal article
- Language
- en
- Update notices
- erratum (2006-11-28)
- Open access
- bronze
- doi.org
- Locations
- Molecular Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
- VU Research Portal (publishedVersion, other-oa)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- DuEPublico (University of Duisburg-Essen) (submittedVersion)
- edoc (University of Basel) (submittedVersion)
- Lancaster EPrints (Lancaster University) (submittedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- GRO (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- National Institutes of Health
- National Institute of Mental Health (R01MH062873)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- attention deficit hyperactivity disorder, combined type ADHD, candidate gene association, single nucleotide polymorphisms, DRD4, DAT1, dopaminergic pathways, serotonin pathway, circadian rhythm genes, tryptophan hydroxylase 2, monoamine oxidase A, phenylethanolamine N-methyltransferase, Hes1, ADRB2, synaptophysin, β-arrestin2
- MeSH terms
- Adolescent, Attention Deficit Disorder with Hyperactivity, Child, Child, Preschool, Genetic Markers, Haplotypes, Humans, Monoamine Oxidase, Pedigree, Receptors, Nicotinic, Tryptophan Hydroxylase, Oncogene Proteins, Linkage Disequilibrium, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide, Siblings, Dopamine Plasma Membrane Transport Proteins, Receptors, Dopamine D4, Synaptosomal-Associated Protein 25
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
