Superparamagnetic iron oxide nanoparticles: from preparations to in vivo MRI applications
Abstract
Superparamagnetic iron oxide nanoparticles have received great attention due to their applications as contrast agents for magnetic resonance imaging (MRI). This feature article briefly introduces the concepts of MRI and MRI contrast agents, and then mainly discusses the synthesis, surface modification, surface functionalization, colloidal stability and biocompatibility of iron oxide particles, followed by their MRI applications.
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Many iron oxide nanoparticles have been evaluated in preclinical and clinical trials, and several have reached the market.
“Many iron oxide nanoparticles have been evaluated in preclinical and clinical trials, and several of them have reached the market (Table 1) [4, 22–26].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [22]
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Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications
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- Authors
- Qiao, R., Yang, C., & Gao, M.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Gao, Mingyuan
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2009
- Volume
- 19
- Issue
- 35
- Pages
- 6274
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2032186406
- Cited by
- 685
- References
- 184
- Citations by year
- 2026: 5 · 2025: 18 · 2024: 17 · 2023: 36 · 2022: 28 · 2021: 30 · 2020: 50 · 2019: 42 · 2018: 41 · 2017: 51 · 2016: 46 · 2015: 73 · 2014: 65 · 2013: 65 · 2012: 56
- FWCI
- 23.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Materials Chemistry (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
- Physical Sciences › Materials Science › Materials Chemistry › Magnetic Properties and Synthesis of Ferrites
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Keywords
- superparamagnetic iron oxide nanoparticles, MRI contrast agents, nanoparticle synthesis, surface functionalization, surface modification, colloidal stability, biocompatibility, magnetic resonance imaging
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