Nanoparticles for Cancer Therapy: Current Progress and Challenges

On the origin of cancer cells

Warburg, O. (1956) · Science · doi:10.1126/science.123.3191.309 · Cited by 13,425 · see citing works

Nanocarriers as an emerging platform for cancer therapy

Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710 · see citing works

Extracellular vesicles: Exosomes, microvesicles, and friends

Raposo, G., & Stoorvogel, W. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201211138 · Cited by 8,099 · see citing works

Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations and biological applications

Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Vander Elst, L., & Muller, R. N. (2008) · Chemical Reviews · doi:10.1021/cr068445e · Cited by 6,852 · see citing works

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Matsumura, Y., & Maeda, H. (1986) · PubMed · Cited by 6,771 · see citing works

Liposomal drug delivery systems: From concept to clinical applications

Allen, T. M., & Cullis, P. R. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.037 · Cited by 4,839 · see citing works

Cancer nanotechnology: opportunities and challenges

Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558 · see citing works

Nanoparticles in cancer therapy and diagnosis

Brigger, I., Dubernet, C., & Couvreur, P. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00044-3 · Cited by 3,040 · see citing works

Nanoparticle-mediated cellular response is size-dependent

Jiang, W., Kim, B. Y. S., Rutka, J. T., & Chan, W. C. W. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.30 · Cited by 2,781 · see citing works

Nanoparticles in Medicine: Therapeutic Applications and Developments

Zhang, L., Gu, F., Chan, J. M., Wang, A. Z., Langer, R., & Farokhzad, O. C. (2007) · Clinical Pharmacology & Therapeutics · doi:10.1038/sj.clpt.6100400 · Cited by 2,685 · see citing works

Exosomes

Pegtel, D. M., & Gould, S. J. (2019) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-013118-111902 · Cited by 2,682 · see citing works

Many roads to maturity: microRNA biogenesis pathways and their regulation

Winter, J. J., Jung, S., Keller, S., Gregory, R. I., & Diederichs, S. (2009) · Nature Cell Biology · doi:10.1038/ncb0309-228 · Cited by 2,646 · see citing works

Cancer is a preventable disease that requires major lifestyle changes

Anand, P., Kunnumakara, A. B., Sundaram, C., Harikumar, K. B., Tharakan, S. T., Lai, O. S., Sung, B., & Aggarwal, B. B. (2008) · Pharmaceutical Research · doi:10.1007/s11095-008-9661-9 · Cited by 2,632 · see citing works

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

Bobo, D., Robinson, K. J., Islam, J., Thurecht, K. J., & Corrie, S. R. (2016) · Pharmaceutical Research · doi:10.1007/s11095-016-1958-5 · Cited by 2,586 · see citing works

Drug resistance in cancer: An overview

Housman, G., Byler, S., Heerboth, S., Lapinska, K., Longacre, M., Snyder, N., & Sarkar, S. (2014) · Cancers · doi:10.3390/cancers6031769 · Cited by 2,463 · see citing works

Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

Hobbs, S. K., Monsky, W. L., Yuan, F., Roberts, W. G., Griffith, L., Torchilin, V. P., & Jain, R. K. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.8.4607 · Cited by 2,438 · see citing works

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

György, B., Szabó, T. G., Pásztói, M., Pál, Z., Misják, P., Aradi, B., László, V., Pállinger, É., Pap, E., Kittel, Á., et al. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0689-3 · Cited by 2,075 · see citing works

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Jing, X., Yang, F., Shao, C., Wei, K., Xie, M., Shen, H., & Shu, Y. (2019) · Molecular Cancer · doi:10.1186/s12943-019-1089-9 · Cited by 2,054 · see citing works

Tumor delivery of macromolecular drugs based on the EPR effect

Torchilin, V. P. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.03.011 · Cited by 2,032 · see citing works

Comparison of the Abilities of Ambient and Manufactured Nanoparticles To Induce Cellular Toxicity According to an Oxidative Stress Paradigm

Xia, T., Kovochich, M., Brant, J. A., Hotze, M., Sempf, J. M., Oberley, T. D., Sioutas, C., Yeh, J. I., Wiesner, M. R., & Nel, A. E. (2006) · Nano Letters · doi:10.1021/nl061025k · Cited by 1,921 · see citing works

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

Kamaly, N., Xiao, Z., Valencia, P. M., Radovic‐Moreno, A. F., & Farokhzad, O. C. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15344k · Cited by 1,734 · see citing works

Active targeting schemes for nanoparticle systems in cancer therapeutics

Byrne, J. D., Betancourt, T., & Brannon‐Peppas, L. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.08.005 · Cited by 1,732 · see citing works

Design of polymeric nanoparticles for biomedical delivery applications

Elsabahy, M., & Wooley, K. L. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15327k · Cited by 1,717 · see citing works

Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies

Jiang, J., Oberdörster, G., & Biswas, P. (2009) · Journal of Nanoparticle Research · doi:10.1007/s11051-008-9446-4 · Cited by 1,713 · see citing works

Immunological aspects of cancer chemotherapy

Zitvogel, L., Apetoh, L., Ghiringhelli, F., & Kroemer, G. (2008) · Nature Reviews Immunology · doi:10.1038/nri2216 · Cited by 1,712 · see citing works

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Rosenberg, S. A., Restifo, N. P., Yang, J. C.-H., Morgan, R. A., & Dudley, M. E. (2008) · Nature reviews. Cancer · doi:10.1038/nrc2355 · Cited by 1,654 · see citing works

Glycolysis inhibition for anticancer treatment

Pelicano, H., Martin, D. S., Xu, R., & Huang, P. (2006) · Oncogene · doi:10.1038/sj.onc.1209597 · Cited by 1,516 · see citing works

Personalized medicine: Time for one-person trials

Schork, N. J. (2015) · Nature · doi:10.1038/520609a · Cited by 1,229 · see citing works

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

Akinc, A., Zumbuehl, A., Goldberg, M. S., Leshchiner, E. S., Busini, V., Hossain, N., Bacallado, S., Nguyen, D. N., Fuller, J. E., Alvarez, R., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt1402 · Cited by 1,228 · see citing works

Nanoemulsion: an advanced mode of drug delivery system

Jaiswal, M., Dudhe, R., & Sharma, P. K. (2014) · 3 Biotech · doi:10.1007/s13205-014-0214-0 · Cited by 1,205 · see citing works

Zero-dimensional, one-dimensional, two-dimensional and three-dimensional nanostructured materials for advanced electrochemical energy devices

Tiwari, J. N., Tiwari, R. N., & Kim, K. S. (2011) · Progress in Materials Science · doi:10.1016/j.pmatsci.2011.08.003 · Cited by 1,204 · see citing works

Ovarian cancer: strategies for overcoming resistance to chemotherapy

Agarwal, R., & Kaye, S. B. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1123 · Cited by 1,155 · see citing works

Treating metastatic cancer with nanotechnology

Schroeder, A., Heller, D. A., Winslow, M. M., Dahlman, J. E., Pratt, G. W., Langer, R., Jacks, T., & Anderson, D. G. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3180 · Cited by 1,154 · see citing works

Biological applications of quantum dots

Jamieson, T. A., Bakhshi, R., Petrova, D., Pocock, R., Imani, M., & Seifalian, A. M. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.014 · Cited by 1,107 · see citing works

An overview of active and passive targeting strategies to improve the nanocarriers efficiency to tumour sites

Attia, M. F., Anton, N., Wallyn, J., et al. (2019) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.13098 · Cited by 1,082 · see citing works

Quantum Dot−Aptamer Conjugates for Synchronous Cancer Imaging, Therapy, and Sensing of Drug Delivery Based on Bi-Fluorescence Resonance Energy Transfer

Bagalkot, V., Zhang, L., Levy‐Nissenbaum, E., Jon, S., Kantoff, P. W., Langer, R., & Farokhzad, O. C. (2007) · Nano Letters · doi:10.1021/nl071546n · Cited by 1,036 · see citing works

Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution

Dobrovolskaia, M. A., Aggarwal, P., Hall, J. B., & McNeil, S. E. (2008) · Molecular Pharmaceutics · doi:10.1021/mp800032f · Cited by 1,022 · see citing works

Physical and chemical stability of drug nanoparticles

Wu, L., Zhang, J., & Watanabe, W. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.02.001 · Cited by 998 · see citing works

Inorganic nanoparticles as carriers for efficient cellular delivery

Xu, Z. P., Zeng, Q., Lu, G. Q., & Yu, A. (2005) · Chemical Engineering Science · doi:10.1016/j.ces.2005.06.019 · Cited by 976 · see citing works

Lipid-like materials for low-dose, in vivo gene silencing

Love, K. T., Mahon, K. P., Levins, C. G., Whitehead, K. A., Querbes, W., Dorkin, J. R., Qin, J., Cantley, W., Qin, L. L., Racie, T., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910603106 · Cited by 969 · see citing works

Engineering Macrophages for Cancer Immunotherapy and Drug Delivery

Xia, Y., Rao, L., Yao, H., Wang, Z., Ning, P., & Chen, X. (2020) · Advanced Materials · doi:10.1002/adma.202002054 · Cited by 949 · see citing works

Cancer nanomedicine: a review of recent success in drug delivery

Tran, S., DeGiovanni, P.-J., Piel, B. P., & Rai, P. (2017) · Clinical and Translational Medicine · doi:10.1186/s40169-017-0175-0 · Cited by 943 · see citing works

Gastrointestinal Uptake of Biodegradable Microparticles: Effect of Particle Size

Desai, M. P., Labhasetwar, V. D., Amidon, G. L., & Levy, R. J. (1996) · Pharmaceutical Research · doi:10.1023/a:1016085108889 · Cited by 941 · see citing works

Nanoparticle Targeting of Anticancer Drug Improves Therapeutic Response in Animal Model of Human Epithelial Cancer

Kukowska‐Latallo, J. F., Candido, K. A., Cao, Z., Nigavekar, S. S., Majoros, I., Thomas, T. P., Balogh, L. P., Khan, M. K., & Baker, J. R. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3921 · Cited by 912 · see citing works

Liposomal Drug Delivery Systems: An Update Review

Samad, A., Sultana, Y., & Aqil, M. (2007) · Current Drug Delivery · doi:10.2174/156720107782151269 · Cited by 909 · see citing works

Smart Nanoparticles for Drug Delivery Application: Development of Versatile Nanocarrier Platforms in Biotechnology and Nanomedicine

Lombardo, D., Kiselev, M. A., & Caccamo, M. T. (2019) · Journal of Nanomaterials · doi:10.1155/2019/3702518 · Cited by 864 · see citing works

Cancer cells compress intratumour vessels

Padera, T. P., Stoll, B. R., Tooredman, J. B., Capen, D., Tomaso, E. D., & Jain, R. K. (2004) · Nature · doi:10.1038/427695a · Cited by 857 · see citing works

Green synthesis of metal and metal oxide nanoparticles from plant leaf extracts and their applications: A review

Shafey, A. M. E. (2020) · Green Processing and Synthesis · doi:10.1515/gps-2020-0031 · Cited by 839 · see citing works

Turning cold tumors into hot tumors by improving T-cell infiltration

Liu, Y., & Sun, Z. (2021) · Theranostics · doi:10.7150/thno.58390 · Cited by 836 · see citing works

Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms

Ou, L., Song, B., Liang, H., Liu, J., Feng, X., Deng, B., Sun, T., & Shao, L. (2016) · Particle and Fibre Toxicology · doi:10.1186/s12989-016-0168-y · Cited by 814 · see citing works

Progress in Nanomedicine: Approved and Investigational Nanodrugs.

Ventola, C. L. (2017) · Europe PMC (PubMed Central) · Cited by 795 · see citing works

Interaction of high molecular weight kininogen, factor XII, and fibrinogen in plasma at interfaces

Vroman, L., Adams, A., Fischer, G., & Munoz, P. (1980) · Blood · doi:10.1182/blood.v55.1.156.156 · Cited by 781 · see citing works

Antibody-Drug Conjugates in Cancer Therapy

Sievers, E. L., & Senter, P. D. (2012) · Annual Review of Medicine · doi:10.1146/annurev-med-050311-201823 · Cited by 772 · see citing works

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

Jia, G., Han, Y., An, Y., Ding, Y., He, C., Wang, X., & Tang, Q. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.06.029 · Cited by 753 · see citing works

The therapeutic potential of nanobodies

Jovčevska, I., & Muyldermans, S. (2020) · BioDrugs · doi:10.1007/s40259-019-00392-z · Cited by 749 · see citing works

Polymeric nanoparticles for targeted drug delivery system for cancer therapy

Masood, F. (2015) · Materials Science and Engineering C · doi:10.1016/j.msec.2015.11.067 · Cited by 702 · see citing works

Cancer Cell Membrane-Coated Adjuvant Nanoparticles with Mannose Modification for Effective Anticancer Vaccination

Yang, R., Xu, J., Xu, L., Sun, X., Chen, Q., Zhao, Y., Peng, R., & Liu, Z. (2018) · ACS Nano · doi:10.1021/acsnano.7b09041 · Cited by 702 · see citing works

Application of Nanotechnology in Cancer Therapy and Imaging

Wang, X., Yang, L., Chen, Z., & Shin, D. M. (2008) · CA A Cancer Journal for Clinicians · doi:10.3322/ca.2007.0003 · Cited by 696 · see citing works

Albumin-bound formulation of paclitaxel (Abraxane® ABI-007) in the treatment of breast cancer

Tomao, S. (2009) · International Journal of Nanomedicine · doi:10.2147/ijn.s3061 · Cited by 695 · cited 1× · see citing works

Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines

Mahapatro, A., & Singh, D. K. (2011) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-9-55 · Cited by 685 · see citing works

Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies.

Li, W., Zhang, H., Assaraf, Y. G., Zhao, K., Xu, X., Xie, J., Yang, D.-H., & Chen, Z.-S. (2016) · Drug Resistance Updates · doi:10.1016/j.drup.2016.05.001 · Cited by 673 · see citing works

PLGA-Based Nanoparticles in Cancer Treatment

Rezvantalab, S., Drude, N., Moraveji, M. K., Güvener, N., Koons, E. K., Shi, Y., Lammers, T., & Kiessling, F. M. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01260 · Cited by 612 · see citing works

Interstitial Flow and Its Effects in Soft Tissues

Swartz, M. A., & Fleury, M. E. (2007) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.151850 · Cited by 589 · see citing works

Folate-targeted therapeutic and imaging agents for cancer

Low, P. S., & Kularatne, S. A. (2009) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2009.03.022 · Cited by 586 · see citing works

A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles

Zhao, X., Hilliard, L. R., Mechery, S. J., Wang, Y., Bagwe, R. P., Jin, S., & Tan, W. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404806101 · Cited by 568 · see citing works

Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives.

Üner, M., & Yener, G. (2007) · PubMed Central · Cited by 536 · see citing works

Penetration of Intact Skin by Quantum Dots with Diverse Physicochemical Properties

Ryman-Rasmussen, J. P., Riviere, J. E., & Monteiro-Riviere, N. A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj122 · Cited by 535 · see citing works

ATP-binding-cassette (ABC) transport systems: Functional and structural aspects of the ATP-hydrolyzing subunits/domains

Schneider, E., & Hunke, S. (1998) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1998.tb00358.x · Cited by 515 · see citing works

Nanoparticle-Based Immunotherapy for Cancer

Shao, K., Singha, S., Clemente‐Casares, X., Tsai, S. J., Yang, Y., & Santamaría, P. (2014) · ACS Nano · doi:10.1021/nn5062029 · Cited by 472 · see citing works

Current progress of siRNA/shRNA therapeutics in clinical trials

Burnett, J., Rossi, J. J., & Tiemann, K. (2011) · Biotechnology Journal · doi:10.1002/biot.201100054 · Cited by 445 · see citing works

T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy

Melero, I., Rouzaut, A., Motz, G. T., & Coukos, G. (2014) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-0985 · Cited by 439 · see citing works

Evaluating intrinsic and non-intrinsic cancer risk factors

Wu, S., Zhu, W., Thompson, P. A., & Hannun, Y. A. (2018) · Nature Communications · doi:10.1038/s41467-018-05467-z · Cited by 439 · see citing works

Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma

Guo, Y., Wang, D., Song, Q., Wu, T., Zhuang, X., Bao, Y., Kong, M., Yan, Q., Tan, S., & Zhang, Z. (2015) · ACS Nano · doi:10.1021/acsnano.5b01042 · Cited by 414 · see citing works

The next frontier of molecular medicine: Delivery of therapeutics

Jain, R. K. (1998) · Nature Medicine · doi:10.1038/nm0698-655 · Cited by 411 · see citing works

Nanovehicular Intracellular Delivery Systems

Prokop, A., & Davidson, J. M. (2008) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21270 · Cited by 365 · see citing works

Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails

Lacouture, M. E., & Sibaud, V. (2018) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-0384-3 · Cited by 365 · see citing works

Evaluation of HIF-1 inhibitors as anticancer agents

Semenza, G. L. (2007) · Drug Discovery Today · doi:10.1016/j.drudis.2007.08.006 · Cited by 363 · see citing works

A Nonviral DNA Delivery System Based on Surface Modified Silica-Nanoparticles Can Efficiently Transfect Cells in Vitro

Kneuer, C., Sameti, M., Bakowsky, U., Schiestel, T., Schirra, H., Schmidt, H. K., & Lehr, C. (2000) · Bioconjugate Chemistry · doi:10.1021/bc0000637 · Cited by 360 · see citing works

Cyclodextrin-based nanosponges encapsulating camptothecin: Physicochemical characterization, stability and cytotoxicity

Swaminathan, S., Pastero, L., Serpe, L., et al. (2009) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2009.11.003 · Cited by 359 · see citing works

Liposomal encapsulated anti-cancer drugs

Hofheinz, R., Gnad-Vogt, S. U., Beyer, U., et al. (2005) · Anti-Cancer Drugs · doi:10.1097/01.cad.0000167902.53039.5a · Cited by 357 · see citing works

Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer

Kim, D.-W., Kim, S.-Y., Kim, H.-K., Kim, S.-W., Shin, S. W., Kim, J. S., Park, K., Lee, M. Y., & Heo, D. S. (2007) · Annals of Oncology · doi:10.1093/annonc/mdm374 · Cited by 356 · see citing works

Nanomedicine, nanotechnology in medicine

Boisseau, P., & Loubaton, B. (2011) · Comptes Rendus Physique · doi:10.1016/j.crhy.2011.06.001 · Cited by 354 · see citing works

Nanoparticles as carriers for drug delivery in cancer

Dadwal, A., Baldi, A., & Narang, R. K. (2018) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2018.1457039 · Cited by 344 · see citing works

PLA Nano‐ and Microparticles for Drug Delivery: An Overview of the Methods of Preparation

Lassalle, V., & Ferreira, M. L. (2007) · Macromolecular Bioscience · doi:10.1002/mabi.200700022 · Cited by 342 · see citing works

Targeted gold nanoparticles enable molecular CT imaging of cancer: an in vivo study

Popovtzer, R., Reuveni, Motiei, Romman, & Popovtzer (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s25446 · Cited by 301 · see citing works

Photodynamic therapy with fullerenes

Mróz, P., Tegos, G. P., Gali, H., Wharton, T., Sarna, T., & Hamblin, M. R. (2007) · Photochemical & Photobiological Sciences · doi:10.1039/b711141j · Cited by 294 · see citing works

Atu027, a Liposomal Small Interfering RNA Formulation Targeting Protein Kinase N3, Inhibits Cancer Progression

Aleku, M., Schulz, P. M., Keil, O., Santel, A., Schaeper, U., Dieckhoff, B., Janke, O., Endruschat, J., Durieux, B., Röder, N., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-2428 · Cited by 293 · see citing works

Cross-linked Composite Gel Polymer Electrolyte using Mesoporous Methacrylate-Functionalized SiO2 Nanoparticles for Lithium-Ion Polymer Batteries

Shin, W.-K., Cho, J., Kannan, A. G., Lee, Y.-S., & Kim, D. (2016) · Scientific Reports · doi:10.1038/srep26332 · Cited by 288 · see citing works

Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery

Amreddy, N., Babu, A., Muralidharan, R., Panneerselvam, J., Srivastava, A., Ahmed, R. A., Mehta, M., Munshi, A., & Ramesh, R. (2017) · Advances in cancer research · doi:10.1016/bs.acr.2017.11.003 · Cited by 288 · see citing works

Hypoxia‐inducible factor‐1α/interleukin‐1β signaling enhances hepatoma epithelial–mesenchymal transition through macrophages in a hypoxic‐inflammatory microenvironment

Zhang, J., Zhang, Q., Lou, Y., Fu, Q., Chen, Q., Wei, T., Yang, J., Tang, J., Wang, J., Chen, Y., et al. (2018) · Hepatology · doi:10.1002/hep.29681 · Cited by 286 · see citing works

Exosomes Increase the Therapeutic Index of Doxorubicin in Breast and Ovarian Cancer Mouse Models

Hadla, M., Palazzolo, S., Corona, G., Caligiuri, I., Canzonieri, V., Toffoli, G., & Rizzolio, F. (2016) · Nanomedicine · doi:10.2217/nnm-2016-0154 · Cited by 285 · see citing works

Reversion of multidrug resistance by co-encapsulation of doxorubicin and cyclosporin A in polyalkylcyanoacrylate nanoparticles

Soma, C. E., Dubernet, C., Bentolila, D., Benita, S., & Couvreur, P. (2000) · Biomaterials · doi:10.1016/s0142-9612(99)00125-8 · Cited by 281 · see citing works

Nanosponges: A Novel Class of Drug Delivery System - Review

Selvamuthukumar, S., Singireddy, A., Krishnamoorthy, K., & Manavalan, R. (2012) · Journal of Pharmacy & Pharmaceutical Sciences · doi:10.18433/j3k308 · Cited by 274 · see citing works

Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives

Ali, E. S., Sharker, S. M., Islam, M. T., Khan, I. N., Shaw, S., Rahman, M. A., Uddin, S. J., Shill, M. C., Rehman, S., Das, N., et al. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.01.011 · Cited by 273 · see citing works

Graphene-based nanomaterials and their potentials in advanced drug delivery and cancer therapy

Liu, J., Dong, J. Y., Zhang, T., & Peng, Q. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.07.034 · Cited by 272 · see citing works

Evading Immune Cell Uptake and Clearance Requires PEG Grafting at Densities Substantially Exceeding the Minimum for Brush Conformation

Yang, Q., Jones, S. W., Parker, C. L., Zamboni, W. C., Bear, J. E., & Lai, S. K. (2014) · Molecular Pharmaceutics · doi:10.1021/mp400703d · Cited by 269 · see citing works

Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting

Murakami, M., Cabral, H., Matsumoto, Y., Wu, S., Kano, M. R., Yamori, T., Nishiyama, N., & Kataoka, K. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3001385 · Cited by 263 · see citing works

Triple functionalisation of single-walled carbon nanotubes with doxorubicin, a monoclonal antibody, and a fluorescent marker for targeted cancer therapy

Heister, E., Neves, V., Tîlmaciu, C., et al. (2009) · Carbon · doi:10.1016/j.carbon.2009.03.057 · Cited by 260 · see citing works

Regulation of microvascular permeability by vascular endothelial growth factors*

Bates, D. O., Hillman, N. J., Williams, B., Neal, C. R., & Pocock, T. (2002) · Journal of Anatomy · doi:10.1046/j.1469-7580.2002.00066.x · Cited by 259 · see citing works

Graphene oxide selectively targets cancer stem cells, across multiple tumor types: Implications for non-toxic cancer treatment, via “differentiation-based nano-therapy”

Fiorillo, M., Verre, A. F., Iliuţ, M., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.3348 · Cited by 235 · see citing works

The Clinical Translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes

Palazzolo, S., Bayda, S., Hadla, M., Caligiuri, I., Corona, G., Toffoli, G., & Rizzolio, F. (2017) · Current Medicinal Chemistry · doi:10.2174/0929867324666170830113755 · Cited by 228 · see citing works

New opportunities for nanoparticles in cancer immunotherapy

Park, W., Heo, Y.-J., & Han, D. K. (2018) · Biomaterials Research · doi:10.1186/s40824-018-0133-y · Cited by 222 · see citing works

Photodynamic Effect of Polyethylene Glycol–modified Fullerene on Tumor

Tabata, Y., Murakami, Y., & Ikada, Y. (1997) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1997.tb00336.x · Cited by 214 · see citing works

pH-responsive and targeted delivery of curcumin via phenylboronic acid-functionalized ZnO nanoparticles for breast cancer therapy

Kundu, M., Sadhukhan, P., Ghosh, N., Chatterjee, S., Manna, P., Das, J., & Sil, P. C. (2019) · Journal of Advanced Research · doi:10.1016/j.jare.2019.02.036 · Cited by 205 · see citing works

Nanotechnology platforms and physiological challenges for cancer therapeutics

Kim, K. Y. (2007) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2006.12.002 · Cited by 201 · see citing works

Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance.

Allen, J. D., Brinkhuis, R. F., van Deemter, L., Wijnholds, J., & Schinkel, A. H. (2000) · PubMed · Cited by 200 · see citing works

Multistaged Nanovaccines Based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy

Fontana, F., Shahbazi, M., Liu, D., Zhang, H., Mäkilä, E. M., Salonen, J., Hirvonen, J. J., & Santos, H. A. (2016) · Advanced Materials · doi:10.1002/adma.201603239 · Cited by 194 · see citing works

Mesenchymal Stem Cell–Derived Exosomes: A Promising Biological Tool in Nanomedicine

Wei, W., Ao, Q., Wang, X., Cao, Y., Liu, Y., Zheng, S. G., & Tian, X. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.590470 · Cited by 189 · see citing works

Cancer therapy improvement with mesoporous silica nanoparticles combining targeting, drug delivery and PDT

Gary‐Bobo, M., Hocine, O., Brevet, D., et al. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.11.045 · Cited by 186 · see citing works

Cyclodextrins in targeting Application to nanoparticles

Duchêne, D. (1999) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(98)00053-2 · Cited by 180 · see citing works

A new nano-cryosurgical modality for tumor treatment using biodegradable MgO nanoparticles

Di, D.-R., He, Z., Sun, Z., et al. (2012) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2012.02.010 · Cited by 178 · see citing works

Dysregulated pH in Tumor Microenvironment Checkmates Cancer Therapy

Barar, J., & Omidi, Y. (2013) · Europe PMC (PubMed Central) · doi:10.5681/bi.2013.036 · Cited by 177 · see citing works

Development of Idarubicin and Doxorubicin Solid Lipid Nanoparticles to Overcome Pgp-Mediated Multiple Drug Resistance in Leukemia

Ma, P., Dong, X., Swadley, C. L., Gupte, A., Leggas, M. L., Ledebur, H. C., & Mumper, R. J. (2009) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2009.1021 · Cited by 174 · see citing works

Folate-conjugated gold nanoparticle as a new nanoplatform for targeted cancer therapy

Samadian, H., Hosseini-Nami, S., Kamrava, S. K., et al. (2016) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-016-2179-3 · Cited by 170 · see citing works

Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy

Lim, E., Chung, B. H., & Chung, S. J. (2016) · Current Drug Targets · doi:10.2174/1389450117666160602202339 · Cited by 164 · see citing works

Nanoparticulate drug delivery systems for cancer chemotherapy

Saha, R. N., Sekar, V., Bende, G., & Snehalatha, M. (2010) · Molecular Membrane Biology · doi:10.3109/09687688.2010.510804 · Cited by 163 · see citing works

Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model

Bernardi, A., Braganhol, E., Jäger, E., Figueiró, F., Edelweiss, M. I. A., Pohlmann, A. R., Guterres, S. S., & Battastini, A. M. O. (2009) · Cancer Letters · doi:10.1016/j.canlet.2009.02.018 · Cited by 161 · see citing works

Side Effects of Chemotherapy among Cancer Patients in a Malaysian General Hospital: Experiences, Perceptions and Informational Needs from Clinical Pharmacists

Chan, H., & Ismail, S. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.13.5305 · Cited by 159 · see citing works

Doxorubicin-loaded nanospheres bypass tumor cell multidrug resistance

Cuvier, C., Roblot-Treupel, L., Millot, J. M., Lizard, G., Chevillard, S., Manfait, M., Couvreur, P., & Poupon, M. (1992) · Biochemical Pharmacology · doi:10.1016/0006-2952(92)90443-m · Cited by 156 · see citing works

Co-delivery of PDTC and doxorubicin by multifunctional micellar nanoparticles to achieve active targeted drug delivery and overcome multidrug resistance

Fan, L., Li, F., Zhang, H., Wang, Y., Cheng, C., Li, X., Gu, C., Yang, Q., Wu, H., & Zhang, S. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.066 · Cited by 155 · see citing works

Hydrazinocurcumin Encapsuled Nanoparticles “Re-Educate” Tumor-Associated Macrophages and Exhibit Anti-Tumor Effects on Breast Cancer Following STAT3 Suppression

Zhang, X., Tian, W., Cai, X., Wang, X., Dang, W., Tang, H., Cao, H., Wang, L., & Chen, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065896 · Cited by 153 · see citing works

From the Reticuloendothelial to Mononuclear Phagocyte System – The Unaccounted Years

Yona, S., & Gordon, S. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00328 · Cited by 150 · see citing works

The breakthrough of the microbiota

Kroemer, G., & Zitvogel, L. (2018) · Nature Reviews Immunology · doi:10.1038/nri.2018.4 · Cited by 147 · see citing works

Protein corona and nanoparticles: how can we investigate on?

Pederzoli, F., Tosi, G., Vandelli, M. A., Belletti, D., Forni, F., & Ruozi, B. (2017) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1467 · Cited by 146 · see citing works

Nanoscale artificial antigen presenting cells for T cell immunotherapy

Perica, K., Medero, A. D. L., Durai, M., Chiu, Y., Bieler, J. G., Sibener, L. V., Niemöller, M., Assenmacher, M., Richter, A., Edidin, M. A., et al. (2013) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2013.06.015 · Cited by 145 · see citing works

Dendritic cell-based nanovaccines for cancer immunotherapy

Paulis, L. E. M., Mandal, S., Kreutz, M., et al. (2013) · Current Opinion in Immunology · doi:10.1016/j.coi.2013.03.001 · Cited by 145 · see citing works

Nanotechnology-Based Detection and Targeted Therapy in Cancer: Nano-Bio Paradigms and Applications

Mousa, S. A., & Bharali, D. J. (2011) · Cancers · doi:10.3390/cancers3032888 · Cited by 143 · see citing works

The proteomic analysis of breast cell line exosomes reveals disease patterns and potential biomarkers

Risha, Y., Minić, Z., Ghobadloo, S. M., & Berezovski, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-70393-4 · Cited by 142 · see citing works

Theranostic application of nanoemulsions in chemotherapy

Gorain, B., Choudhury, H., Nair, A. B., Dubey, S. K., & Kesharwani, P. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.04.013 · Cited by 139 · see citing works

Novel cationic solid lipid nanoparticles enhanced p53 gene transfer to lung cancer cells

Choi, S. H. (2007) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2007.07.011 · Cited by 136 · see citing works

Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance

Zhao, Y., Huan, M., Liu, M., Cheng, Y., Sun, Y., Cui, H., Liu, D., Mei, Q., & Zhou, S. (2016) · Scientific Reports · doi:10.1038/srep35267 · Cited by 130 · see citing works

Nanoparticle-Mediated Wild-Type p53 Gene Delivery Results in Sustained Antiproliferative Activity in Breast Cancer Cells

Prabha, S., & Labhasetwar, V. D. (2004) · Molecular Pharmaceutics · doi:10.1021/mp049970+ · Cited by 128 · see citing works

Dendrimer Nanoscaffolds for Potential Theranostics of Prostate Cancer with a Focus on Radiochemistry

Lo, S., Kumar, A., Hsieh, J., & Sun, X. (2013) · Molecular Pharmaceutics · doi:10.1021/mp3005325 · Cited by 126 · see citing works

Recent Advances in Macrophage-Mediated Drug Delivery Systems

Liang, T., Zhang, R., Liu, X., Ding, Q., Wu, S., Li, C., Lin, Y., Ye, Y., Zhong, Z., & Zhou, M. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s298159 · Cited by 126 · see citing works

Fullerenes for Cancer Diagnosis and Therapy: Preparation, Biological and Clinical Perspectives

Chen, Z., Mao, R., & Liu, Y. (2012) · Current Drug Metabolism · doi:10.2174/138920012802850128 · Cited by 125 · see citing works

Graphene-Based Nanomaterials for Nanobiotechnology and Biomedical Applications

Krishna, K. V., Ménard‐Moyon, C., Verma, S. K., et al. (2013) · Nanomedicine · doi:10.2217/nnm.13.140 · Cited by 123 · see citing works

Nanoparticles for tumor immunotherapy

Zang, X., Zhao, X., Hu, H., Qiao, M., Deng, Y., & Chen, D. (2017) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2017.03.013 · Cited by 122 · see citing works

HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity

Reynolds, J. G., Geretti, E., Hendriks, B. S., Lee, H., Leonard, S. C., Klinz, S. G., Noble, C. O., Lücker, P. B., Zandstra, P. W., Drummond, D. C., et al. (2012) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2012.04.008 · Cited by 120 · see citing works

Solid lipid nanoparticles of mitoxantrone for local injection against breast cancer and its lymph node metastases

Lu, B., Xiong, S.-B., Yang, H., et al. (2006) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2006.01.001 · Cited by 120 · see citing works

Overcoming STC2 mediated drug resistance through drug and gene co-delivery by PHB-PDMAEMA cationic polyester in liver cancer cells

Cheng, H., Wu, Z., Wu, C., Wang, X., Liow, S. S., Li, Z., & Wu, Y.-L. (2018) · Materials Science and Engineering C · doi:10.1016/j.msec.2017.08.075 · Cited by 119 · see citing works

Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles

Choi, K. Y., Correa, S., Min, J., Li, J., Roy, S., Laccetti, K. H., Dreaden, E. C., Kong, S. M., Heo, R., Roh, Y. H., et al. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201900018 · Cited by 119 · see citing works

Targeting tumor microenvironment: crossing tumor interstitial fluid by multifunctional nanomedicines

Omidi, Y., & Barar, J. (2014) · Europe PMC (PubMed Central) · doi:10.5681/bi.2014.021 · Cited by 116 · see citing works

An Avidity-Based PD-L1 Antagonist Using Nanoparticle-Antibody Conjugates for Enhanced Immunotherapy

Bu, J., Nair, A., Iida, M., Jeong, W., Poellmann, M. J., Mudd, K., Kubiatowicz, L. J., Liu, E. W., Wheeler, D. L., & Hong, S. (2020) · Nano Letters · doi:10.1021/acs.nanolett.0c00953 · Cited by 115 · see citing works

Reversal of drug resistance by planetary ball milled (PBM) nanoparticle loaded with resveratrol and docetaxel in prostate cancer

Singh, S. K., Lillard, J. W., & Singh, R. (2018) · Cancer Letters · doi:10.1016/j.canlet.2018.04.017 · Cited by 113 · see citing works

An analytical study on the thermal effects of cryosurgery on selective cell destruction

Chua, K. J., Chou, S. K., & Ho, J. C. (2005) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2005.11.005 · Cited by 109 · see citing works

Apoptotic Pathways and Therapy Resistance in Human Malignancies

Viktorsson, K., Lewensohn, R., & Zhivotovsky, B. (2005) · Advances in cancer research · doi:10.1016/s0065-230x(05)94004-9 · Cited by 108 · see citing works

Rational Design of a Transferrin-Binding Peptide Sequence Tailored to Targeted Nanoparticle Internalization

Santi, M., Maccari, G., Mereghetti, P., Voliani, V., Rocchiccioli, S., Ucciferri, N., Luin, S., & Signore, G. (2016) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.6b00611 · Cited by 103 · see citing works

Co-Delivery of Curcumin and Paclitaxel by “Core-Shell” Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer

Zhao, M., Li, J.-Q., Chen, F., Dong, W., Wen, L., Fei, W., Zhang, X., Yang, P.-L., Zhang, X., & Zheng, C. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s224579 · Cited by 102 · see citing works

Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration

Muralidharan, R., Babu, A., Amreddy, N., Basalingappa, K. M., Mehta, M., Chen, A., Zhao, Y. D., Kompella, U. B., Munshi, A., & Ramesh, R. (2016) · Journal of Nanobiotechnology · doi:10.1186/s12951-016-0201-1 · Cited by 99 · see citing works

Self-Assembly of Gold Nanoparticles Shows Microenvironment-Mediated Dynamic Switching and Enhanced Brain Tumor Targeting

Feng, Q., Shen, Y., Fu, Y., Muroski, M. E., Zhang, P., Wang, Q., Xu, C., Lesniak, M. S., Li, G., & Cheng, Y. (2017) · Theranostics · doi:10.7150/thno.18985 · Cited by 99 · see citing works

Targeted magnetic nanoparticle hyperthermia for the treatment of oral cancer

Legge, C. J., Colley, H. E., Lawson, M. A., & Rawlings, A. E. (2019) · Journal of Oral Pathology and Medicine · doi:10.1111/jop.12921 · Cited by 96 · see citing works

Labeling Stem Cells with Ferumoxytol, an FDA-Approved Iron Oxide Nanoparticle

Castaneda, R., Khurana, A., Khan, R., & Daldrup-Link, H. E. (2011) · Journal of Visualized Experiments · doi:10.3791/3482 · Cited by 95 · see citing works

Paclitaxel Loaded Nanosponges: In-Vitro Characterization and Cytotoxicity Study on MCF-7 Cell Line Culture

Ansari, K. A., Torne, S. J., Vavia, P. R., et al. (2011) · Current Drug Delivery · doi:10.2174/156720111794479934 · Cited by 94 · see citing works

LHRH-functionalized superparamagnetic iron oxide nanoparticles for breast cancer targeting and contrast enhancement in MRI

Meng, J., Fan, J., Galiana, G., Branca, R. T., Clasen, P. L., Ma, S., Zhou, J., Leuschner, C., Kumar, C. S. S. R., Hormes, J., et al. (2008) · Materials Science and Engineering C · doi:10.1016/j.msec.2008.09.039 · Cited by 92 · see citing works

Improving Cancer Immunotherapy Outcomes Using Biomaterials

Yan, S., Luo, Z., Li, Z., Wang, Y., Tao, J., Gong, C., & Liu, X. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202002780 · Cited by 90 · see citing works

Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy

Ramesh, R., Amreddy, N., Muralidharan, R., et al. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s93237 · Cited by 87 · see citing works

Synthesis of Large Dendrimers with the Dimensions of Small Viruses

Lim, J., Kostiainen, M. A., Malý, J., et al. (2013) · Journal of the American Chemical Society · doi:10.1021/ja400432e · Cited by 87 · see citing works

pH and redox dual-responsive nanoparticles based on disulfide-containing poly(β-amino ester) for combining chemotherapy and COX-2 inhibitor to overcome drug resistance in breast cancer

Zhang, S., Guo, N., Wan, G., et al. (2019) · Journal of Nanobiotechnology · doi:10.1186/s12951-019-0540-9 · Cited by 86 · see citing works

Construction of stable anionic liposome-plasmid particles using the heating method: a preliminary investigation.

Mozafari, M. R., Reed, C. J., Rostron, C., Kocum, C., & Piskin, E. (2002) · PubMed · Cited by 84 · see citing works

Nutlin‐3a and Cytokine Co‐loaded Spermine‐Modified Acetalated Dextran Nanoparticles for Cancer Chemo‐Immunotherapy

Bauleth‐Ramos, T., Shahbazi, M., Liu, D., Fontana, F., Correia, A., Figueiredo, P., Zhang, H., Martins, J. P., Hirvonen, J. J., Granja, P. L., et al. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201703303 · Cited by 84 · see citing works

Nanotopography Directs Mesenchymal Stem Cells to Osteoblast Lineage Through Regulation of microRNA‐SMAD‐BMP‐2 Circuit

Kato, R. B., Roy, B., Oliveira, F. S., et al. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24614 · Cited by 81 · see citing works

Nano-graphene oxide-manganese dioxide nanocomposites for overcoming tumor hypoxia and enhancing cancer radioisotope therapy

Tao, Y., Zhu, L., Zhao, Y., Yi, X., Zhu, L., Ge, F., Mou, X., Chen, L., Sun, L., & Yang, K. (2018) · Nanoscale · doi:10.1039/c7nr08747k · Cited by 81 · see citing works

Optimization and charaterization of repaglinide biodegradable polymeric nanoparticle loaded transdermal patchs: In vitro and in vivo studies

Venugopal, V., Reddy, K. R., Sakthivel, S., et al. (2013) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2013.05.020 · Cited by 79 · see citing works

Silencing of HIF-1α/CD73 axis by siRNA-loaded TAT-chitosan-spion nanoparticles robustly blocks cancer cell progression

Hajizadeh, F., Ardebili, S. M., Moornani, M. B., Masjedi, A., Atyabi, F., Kiani, M., Namdar, A., Karpisheh, V., Izadi, S., Baradaran, B., et al. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173235 · Cited by 75 · see citing works

Role of p-glycoprotein expression in predicting response to neoadjuvant chemotherapy in breast cancer-a prospective clinical study

Chintamani, C., Singh, J., Mittal, M. K., et al. (2005) · World Journal of Surgical Oncology · doi:10.1186/1477-7819-3-61 · Cited by 70 · see citing works

Cytotoxicity evaluation of anionic nanoliposomes and nanolipoplexes prepared by the heating method without employing volatile solvents and detergents

Mozafari, M. R., Reed, C. J., & Rostron, C. (2007) · Die Pharmazie · doi:10.31083/ph.2007.3.6045 · Cited by 68 · see citing works

Nanoparticle-mediated cryosurgery for tumor therapy

Hou, Y., Sun, Z., Rao, W., et al. (2017) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2017.11.018 · Cited by 67 · see citing works

Programmable nanoparticle functionalization for in vivo targeting

Pan, H., Myerson, J. W., Hu, L., et al. (2012) · The FASEB Journal · doi:10.1096/fj.12-218081 · Cited by 66 · see citing works

Nano-Cryosurgery: Advances and Challenges

Liu, J., & Deng, Z. (2009) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2009.1264 · Cited by 61 · see citing works

A degradable triple temperature‐, pH‐, and redox‐responsive drug system for cancer chemotherapy

Yu, B., Song, N., Hu, H., Chen, G., Shen, Y., & Cong, H. (2018) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36515 · Cited by 61 · see citing works

Augmentation of Therapeutic Efficacy in Drug-Resistant Tumor Models Using Ceramide Coadministration in Temporal-Controlled Polymer-Blend Nanoparticle Delivery Systems

van Vlerken, L. E., Duan, Z., Little, S. R., Seiden, M. V., & Amiji, M. M. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9174-4 · Cited by 57 · see citing works

Sensitivity to antitubulin chemotherapeutics is potentiated by a photoactivable nanoliposome

Wang, X., Liu, X., Li, Y., Wang, P., Feng, X., Liu, Q., Yan, F., & Zheng, H. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.06.034 · Cited by 57 · see citing works

Nanoemulsions as Delivery Systems for Poly-Chemotherapy Aiming at Melanoma Treatment

Dianzani, C., Monge, C., Miglio, G., Serpe, L., Martina, K., Cangemi, L., Ferraris, C., Mioletti, S., Osella, S., Gigliotti, C. L., et al. (2020) · Cancers · doi:10.3390/cancers12051198 · Cited by 54 · see citing works

Antibody–drug nanoparticle induces synergistic treatment efficacies in HER2 positive breast cancer cells

Abedin, M. R., Powers, K., Aiardo, R., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-86762-6 · Cited by 53 · see citing works

Targeted brain delivery of methotrexate by glutathione PEGylated liposomes: How can the formulation make a difference?

Hu, Y., Gaillard, P. J., de Lange, E. C. M., et al. (2019) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2019.04.004 · Cited by 52 · see citing works

Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review

Maurya, A., Singh, A. K., Mishra, G., Kumari, K., Rai, A., Sharma, B., Kulkarni, G. T., & Awasthi, R. (2019) · Interventional Medicine and Applied Science · doi:10.1556/1646.11.2019.04 · Cited by 51 · see citing works

Magnetic nanoparticle-mediated gene therapy to induce Fas apoptosis pathway in breast cancer

Başoğlu, H., Göncü, B., & Akbaş, F. (2018) · Cancer Gene Therapy · doi:10.1038/s41417-018-0017-2 · Cited by 41 · see citing works

Cancer Cell Membrane Decorated Silica Nanoparticle Loaded with miR495 and Doxorubicin to Overcome Drug Resistance for Effective Lung Cancer Therapy

He, J., Gong, C., Qin, J., et al. (2019) · Nanoscale Research Letters · doi:10.1186/s11671-019-3143-3 · Cited by 39 · see citing works

Calcium based non-viral gene delivery: an overview of methodology and applications.

Khosravi‐Darani, K., Mozafari, M. R., Rashidi, L., et al. (2011) · PubMed · Cited by 37 · see citing works

Design and development of spirulina polysaccharide-loaded nanoemulsions with improved the antitumor effects of paclitaxel

Du, M., Yang, Z., Lü, W., Wang, B., Wang, Q., Chen, Z., Chen, L., Han, S., Cai, T., & Cai, Y. (2020) · Journal of Microencapsulation · doi:10.1080/02652048.2020.1767224 · Cited by 37 · see citing works

Hypo-fractionated radiation, magnetic nanoparticle hyperthermia and a viral immunotherapy treatment of spontaneous canine cancer

Hoopes, P. J., Moodie, K. L., Petryk, A. A., Petryk, J. D., Sechrist, S., Gladstone, D. J., Steinmetz, N. F., Veliz, F. A., Bursey, A. A., Wagner, R. J., et al. (2017) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2256213 · Cited by 36 · see citing works

Ceramide–Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations

Khiste, S., Liu, Z., Roy, K. R., Uddin, M. B., Hosain, S. B., Gu, X., Nazzal, S., Hill, R. A., & Liu, Y. (2019) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-19-0366 · Cited by 34 · see citing works

Distinct Proteins in Protein Corona of Nanoparticles Represent a Promising Venue for Endogenous Targeting – Part I: In vitro Release and Intracellular Uptake Perspective

Sebak, A. A., Gomaa, I. E. O., ElMeshad, A. N., et al. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s273713 · Cited by 32 · see citing works

Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model

Long, Q., Lin, T., Huang, Y., et al. (2018) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2017.12.014 · Cited by 31 · see citing works

Opportunities and Challenges in Nano-structure Mediated Drug Delivery: Where Do We Stand?

Awasthi, R., Pant, I., Kulkarni, G. T., et al. (2016) · Current Nanomedicine · doi:10.2174/2468187306666160808160330 · Cited by 29 · see citing works

Development of Dehydration-Rehydration Liposomal System Using Film Hydration Technique Followed by Sonication

Visht, S., Awasthi, R., Rai, R., et al. (2014) · Current Drug Delivery · doi:10.2174/1567201811666140910122945 · Cited by 28 · see citing works

An Overview of CAR T Cell Mediated B Cell Maturation Antigen Therapy

Quazi, S. (2021) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/j.clml.2021.12.003 · Cited by 24 · see citing works

DaunoXome® (Liposomal Daunorubicin) for First-Line Treatment of Advanced, HIV-Related Kaposi’s Sarcoma

Mukwaya, G., Forssen, E. A., Schmidt, P., et al. (1998) · Springer eBooks · doi:10.1007/978-3-662-22115-0_10 · Cited by 13 · see citing works

Elucidation of CRISPR-Cas9 Application in Novel Cellular Immunotherapy.Preprint

Quazi, S. (2021) · Preprints.org · doi:10.20944/preprints202108.0387.v1 · Cited by 12 · see citing works

Telomerase Gene Therapy: A Remission Towards CancerPreprint

Quazi, S. (2021) · Preprints.org · doi:10.20944/preprints202110.0407.v1 · Cited by 9 · see citing works

[Effect of hypoxia on expression of multidrug resistance protein 2 and its regulation mechanism].

Luo, B., Li, W., Wang, R., et al. (2017) · PubMed · doi:10.11817/j.issn.1672-7347.2017.01.016 · Cited by 4 · see citing works

Wnt/β-catenin-driven EMT regulation in human cancers

Xue, W., Yang, L., Chen, C., Ashrafizadeh, M., Tian, Y., & Sun, R. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-05099-7 · Cited by 321 · see citing works

Approaches to Improve EPR-Based Drug Delivery for Cancer Therapy and Diagnosis

Subhan, M. A., Parveen, F., Filipczak, N., Yalamarty, S. S. K., & Torchilin, V. P. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13030389 · Cited by 98 · see citing works

Enhancing Proton Therapy Efficacy Through Nanoparticle-Mediated Radiosensitization

Ma, J., Shen, H., & Mi, Z. (2024) · Cells · doi:10.3390/cells13221841 · Cited by 23 · see citing works

Editorial: Nanomedicine-Based Drug Delivery Systems: Recent Developments and Future Prospects

Shakeel, F. (2023) · Molecules · doi:10.3390/molecules28104138 · Cited by 12 · see citing works

Therapeutic Nanomedicine CROSSLINKED MICELLES WITH TRANSIENTLY LINKED DRUGS – A VERSATILE DRUG DELIVERY SYSTEM

Rijcken, C. J. F., Talelli, M., van Nostrum, C. F., et al. (2016) · nano Online · doi:10.1515/nano.0012.00024

Nanomedicine-based cancer immunotherapy: recent trends and future perspectives

Lakshmanan, V., Jindal, S., Packirisamy, G., Ojha, S. K., Lian, S., Kaushik, A. K., Alzarooni, A. I. M. A., Metwally, Y. H. H., Thyagarajan, S. P., Jung, Y. D., et al. (2021) · Cancer Gene Therapy · doi:10.1038/s41417-021-00299-4 · Cited by 76 · see citing works

Programmed ROS/CO-releasing nanomedicine for synergetic chemodynamic-gas therapy of cancer

Zhao, B., Zhao, P., Jin, Z., Fan, M., Jin, M., & He, Q. (2019) · Journal of Nanobiotechnology · doi:10.1186/s12951-019-0507-x · Cited by 69 · see citing works

Immunomodulating Nanomedicine for Cancer Therapy

Liu, Z., Jiang, W., Nam, J., Moon, J. J., & Kim, B. Y. S. (2018) · Nano Letters · doi:10.1021/acs.nanolett.8b02340 · Cited by 154 · see citing works