Angiocrine Signaling in Sinusoidal Health and Disease

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

The Tabula Muris Consortium, coordination, O., coordination, L., processing, O. C. A., sequencing, L. P. A., analysis, C. D., annotation, C. T., Writing group, Supplemental text writing group, & Principal investigators (2018) · Nature · doi:10.1038/s41586-018-0590-4 · Cited by 3,326 · see citing works

Non-alcoholic fatty liver disease - a global public health perspective

Younossi, Z. M. (2019) · Journal of Hepatology · doi:10.1016/j.jhep.2018.10.033 · Cited by 2,149 · see citing works

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

Ramachandran, P., Dobie, R., Wilson-Kanamori, J. R., Dora, E. F., Henderson, B. E. P., Luu, N. T., Portman, J. R., Matchett, K. P., Brice, M., Marwick, J. A., et al. (2019) · Nature · doi:10.1038/s41586-019-1631-3 · Cited by 1,784 · see citing works

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

MacParland, S. A., Liu, J. C., Ma, X.-Z., Innes, B. T., Bartczak, A. M., Gage, B. K., Manuel, J., Khuu, N., Echeverri, J., Linares, I., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06318-7 · Cited by 1,552 · see citing works

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Kalucka, J. M., de Rooij, L. P. M. H., Goveia, J., Rohlenová, K., Dumas, S. J., Meta, E., Conchinha, N. V., Taverna, F., Teuwen, L.-A. M. N., Veys, K., et al. (2020) · Cell · doi:10.1016/j.cell.2020.01.015 · Cited by 1,362 · see citing works

Liver fibrosis and repair: Immune regulation of wound healing in a solid organ

Pellicoro, A., Ramachandran, P., Iredale, J. P., & Fallowfield, J. A. (2014) · Nature Reviews Immunology · doi:10.1038/nri3623 · Cited by 1,310 · see citing works

A human liver cell atlas reveals heterogeneity and epithelial progenitors

Aizarani, N., Saviano, A., Sagar, Mailly, L., Durand, S., Herman, J. S., Pessaux, P., Baumert, T. F., & Grün, D. (2019) · Nature · doi:10.1038/s41586-019-1373-2 · Cited by 1,147 · see citing works

Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

Halpern, K. B., Shenhav, R., Matcovitch-Natan, O., Tóth, B., Lemze, D., Golan, M., Massasa, E. E., Baydatch, S., Landen, S., Moor, A. E., et al. (2017) · Nature · doi:10.1038/nature21065 · Cited by 1,059 · see citing works

Liver sinusoidal endothelial cells: Physiology and role in liver diseases

Poisson, J., Lemoinne, S., Boulanger, C., Durand, F., Moreau, R., Valla, D., & Rautou, P.-E. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2016.07.009 · Cited by 1,047 · see citing works

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Guilliams, M., Bonnardel, J., Haest, B., Vanderborght, B., Wagner, C., Remmerie, A., Bujko, A., Martens, L., Thoné, T., Browaeys, R., et al. (2022) · Cell · doi:10.1016/j.cell.2021.12.018 · Cited by 985 · see citing works

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Scott, C. L., Zheng, F., De Baetselier, P., Martens, L., Saeys, Y., De Prijck, S., Lippens, S., Abels, C., Schoonooghe, S., Raes, G., et al. (2016) · Nature Communications · doi:10.1038/ncomms10321 · Cited by 860 · see citing works

Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning

Jaeschke, H. (2003) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00342.2002 · Cited by 859 · see citing works

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration

Ding, B., Nolan, D. J., Butler, J. M., James, D., Babazadeh, A. O., Rosenwaks, Z., Mittal, V., Kobayashi, H., Shido, K., Lyden, D. C., et al. (2010) · Nature · doi:10.1038/nature09493 · Cited by 837 · see citing works

What are super-enhancers?

Pott, S., & Lieb, J. D. (2014) · Nature Genetics · doi:10.1038/ng.3167 · Cited by 745 · see citing works

Prophylactic Treatment with Cerium Oxide Nanoparticles Attenuate Hepatic Ischemia Reperfusion Injury in Sprague Dawley Rats

Manne, N. D. P. K., Arvapalli, R., Graffeo, V. A., Bandarupalli, V. V. K., Shokuhfar, T., Patel, S. B., Rice, K. M., Ginjupalli, G. K., & Blough, E. R. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479540 · Cited by 702 · see citing works

An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids

Wisse, E. (1970) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(70)90150-4 · Cited by 655 · see citing works

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

Bonnardel, J., T’Jonck, W., Gaublomme, D., Browaeys, R., Scott, C. L., Martens, L., Vanneste, B., De Prijck, S., Nedospasov, S. A., Kremer, A., et al. (2019) · Immunity · doi:10.1016/j.immuni.2019.08.017 · Cited by 631 · see citing works

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

Ding, B.-S., Cao, Z., Lis, R., Nolan, D. J., Guo, P., Simons, M., Penfold, M. E., Shido, K., Rabbany, S. Y., & Rafii, S. (2014) · Nature · doi:10.1038/nature12681 · Cited by 626 · see citing works

Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages.

van de Laar, L., Saelens, W., Prijck, S. D., Martens, L., Scott, C. L., Isterdael, G. V., Hoffmann, E., Beyaert, R., Saeys, Y., Lambrecht, B., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.017 · Cited by 576 · see citing works

Liver sinusoidal endothelial cells in hepatic fibrosis

DeLeve, L. D. (2015) · Hepatology · doi:10.1002/hep.27376 · Cited by 482 · see citing works

Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation.

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Role of liver sinusoidal endothelial cells in liver diseases

Gracia‐Sancho, J., Caparrós, E., Fernández‐Iglesias, A., & Francés, R. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-00411-3 · Cited by 425 · see citing works

Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis

Dobie, R., Wilson-Kanamori, J. R., Henderson, B. E. P., Smith, J. R., Matchett, K. P., Portman, J. R., Wallenborg, K., Picelli, S., Zagorska, A., Pendem, S. V., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.10.024 · Cited by 420 · see citing works

Does niche competition determine the origin of tissue-resident macrophages?

Guilliams, M., & Scott, C. L. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.42 · Cited by 409 · see citing works

Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence

DeLeve, L. D., Wang, X., & Guo, Y. (2008) · Hepatology · doi:10.1002/hep.22351 · Cited by 408 · see citing works

Pathophysiology of decompensated cirrhosis: Portal hypertension, circulatory dysfunction, inflammation, metabolism and mitochondrial dysfunction

Engelmann, C., Clària, J., Szabó, G., Bosch, J., & Bernardi, M. (2021) · Journal of Hepatology · doi:10.1016/j.jhep.2021.01.002 · Cited by 407 · see citing works

Liver macrophages in health and disease

Guilliams, M., & Scott, C. L. (2022) · Immunity · doi:10.1016/j.immuni.2022.08.002 · Cited by 395 · see citing works

Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span

Grunewald, M., Kumar, S., Sharife, H., Volinsky, E., Gileles‐Hillel, A., Licht, T., Permyakova, A., Hinden, L., Azar, S., Friedmann, Y., et al. (2021) · Science · doi:10.1126/science.abc8479 · Cited by 370 · see citing works

Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells

Halpern, K. B., Shenhav, R., Massalha, H., Toth, B., Egozi, A., Massasa, E. E., Medgalia, C., David, E., Giladi, A., Moor, A. E., et al. (2018) · Nature Biotechnology · doi:10.1038/nbt.4231 · Cited by 368 · see citing works

Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids.

Shah, V. H., Haddad, F., García‐Cardeña, G., Frangos, J. A., Mennone, A., Groszmann, R. J., & Sessa, W. C. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119842 · Cited by 349 · see citing works

The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity

Pruenster, M., Mudde, L., Bombosi, P., Dimitrova, S., Zsak, M., Middleton, J., Richmond, A. J., Graham, G. J., Segerer, S., Nibbs, R. J. B., et al. (2008) · Nature Immunology · doi:10.1038/ni.1675 · Cited by 340 · see citing works

An integrated view of anti-inflammatory and antifibrotic targets for the treatment of NASH

Tacke, F., Puengel, T., Loomba, R., & Friedman, S. L. (2023) · Journal of Hepatology · doi:10.1016/j.jhep.2023.03.038 · Cited by 321 · see citing works

Hallmarks of Aging in the Liver

Hunt, N. J., Kang, S. W., Lockwood, G. P., Couteur, D. G. L., & Cogger, V. C. (2019) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2019.07.021 · Cited by 315 · see citing works

Single‐Cell, Single‐Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity

Andrews, T. S., Atif, J., Liu, J. C., Perciani, C. T., Ma, X., Thoeni, C., Slyper, M., Eraslan, G., Segerstolpe, A., Manuel, J., et al. (2022) · Hepatology Communications · doi:10.1002/hep4.1854 · Cited by 307 · see citing works

Hepatic microcirculation and mechanisms of portal hypertension

Gracia‐Sancho, J., Marrone, G., & Fernández‐Iglesias, A. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0097-3 · Cited by 288 · see citing works

Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis

Gao, J., Wei, B., de Assuncao, T. M., Liu, Z., Hu, X., Ibrahim, S., Cooper, S. A., Cao, S., Shah, V. H., & Kostallari, E. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2020.04.044 · Cited by 288 · see citing works

Single-Cell RNA Sequencing Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells

Paik, D. T., Tian, L., Williams, I. M., Rhee, S., Zhang, H., Liu, C., Mishra, R., Wu, S. M., Red‐Horse, K., & Wu, J. C. (2020) · Circulation · doi:10.1161/circulationaha.119.041433 · Cited by 282 · see citing works

Pivotal role of liver sinusoidal endothelial cells in NAFLD/NASH progression

Miyao, M., Kotani, H., Ishida, T., Kawai, C., Manabe, S., Abiru, H., & Tamaki, K. (2015) · Laboratory Investigation · doi:10.1038/labinvest.2015.95 · Cited by 255 · see citing works

Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis

Ramachandran, P., Matchett, K. P., Dobie, R., Wilson-Kanamori, J. R., & Henderson, N. C. (2020) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-0304-x · Cited by 253 · see citing works

Evolution in the understanding of the pathophysiological basis of portal hypertension: How changes in paradigm are leading to successful new treatments

Bosch, J., Groszmann, R. J., & Shah, V. H. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.01.003 · Cited by 252 · see citing works

Sinusoidal Endothelial Dysfunction Precedes Inflammation and Fibrosis in a Model of NAFLD

Pasarín, M., Mura, V. L., Gracia‐Sancho, J., García‐Calderó, H., Rodrı́guez-Vilarrupla, A., García‐Pagán, J. C., Bosch, J., & Abraldeṣ, J. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032785 · Cited by 251 · see citing works

The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial–stellate cell deactivation induced by statins

Marrone, G., Russo, L., Rosado, E., Hide, D., García‐Cardeña, G., García‐Pagán, J. C., Bosch, J., & Gracia‐Sancho, J. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.08.026 · Cited by 244 · see citing works

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D. A., Yaqoob, U., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.03.013 · Cited by 240 · see citing works

Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy

Iwakiri, Y., & Trebicka, J. (2021) · JHEP Reports · doi:10.1016/j.jhepr.2021.100316 · Cited by 237 · see citing works

LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

Xu, M., Xu, H., Yuan, L., Sun, X., Wang, L., Fang, Z., Su, X., Liang, X.-J., Hu, Y., Liu, Z., et al. (2019) · Cell · doi:10.1016/j.cell.2019.07.021 · Cited by 224 · see citing works

The spatiotemporal program of zonal liver regeneration following acute injury

Ben-Moshe, S., Veg, T., Manco, R., Dan, S., Papinutti, D., Lifshitz, A., Kolodziejczyk, A. A., Bahar Halpern, K., Elinav, E., & Itzkovitz, S. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.04.008 · Cited by 224 · see citing works

KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins

Marrone, G., Maeso-Díaz, R., García-Cardena, G., Abraldes, J. G., García-Pagán, J. C., Bosch, J., & Gracia-Sancho, J. (2015) · Gut · doi:10.1136/gutjnl-2014-308338 · Cited by 222 · see citing works

Single-Cell Transcriptomics Reveals Zone-Specific Alterations of Liver Sinusoidal Endothelial Cells in Cirrhosis

Su, T., Yang, Y., Lai, S., Jeong, J., Jung, Y., McConnell, M., Utsumi, T., & Iwakiri, Y. (2021) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2020.12.007 · Cited by 220 · see citing works

Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis

Weston, C. J., Shepherd, E. L., Claridge, L. C., Rantakari, P., Curbishley, S. M., Tomlinson, J., Hübscher, S. G., Reynolds, G. M., Aalto, K., Anstee, Q. M., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci73722 · Cited by 214 · see citing works

Short‐ or long‐term high‐fat diet feeding plus acute ethanol binge synergistically induce acute liver injury in mice: An important role for CXCL1

Chang, B., Xu, M., Zhou, Z., Cai, Y., Li, M., Wang, W., Feng, D., Bertola, A., Wang, H., Kunos, G., et al. (2015) · Hepatology · doi:10.1002/hep.27921 · Cited by 213 · see citing works

Toll‐like receptor‐induced innate immune responses in non‐parenchymal liver cells are cell type‐specific

Wu, J., Meng, Z., Jiang, M., Zhang, E., Trippler, M., Broering, R., Bucchi, A., Krux, F., Dittmer, U., Yang, D., et al. (2009) · Immunology · doi:10.1111/j.1365-2567.2009.03179.x · Cited by 213 · see citing works

Role of hepatic resident and infiltrating macrophages in liver repair after acute injury

You, Q., Holt, M. R., Yin, H., Li, G., Hu, C., & Ju, C. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.07.006 · Cited by 204 · see citing works

The evolving role of liver sinusoidal endothelial cells in liver health and disease

McConnell, M. J., Kostallari, E., Ibrahim, S. H., & Iwakiri, Y. (2023) · Hepatology · doi:10.1097/hep.0000000000000207 · Cited by 189 · see citing works

A defect in endothelial autophagy occurs in patients with non-alcoholic steatohepatitis and promotes inflammation and fibrosis

Hammoutene, A., Biquard, L., Lasselin, J., Kheloufi, M., Tanguy, M., Vion, A.-C., Mérian, J., Colnot, N., Loyer, X., Tedgui, A., et al. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2019.10.028 · Cited by 188 · see citing works

Regulation of tissue morphogenesis by endothelial cell-derived signals

Ramasamy, S. K., Kusumbe, A. P., & Adams, R. H. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.11.007 · Cited by 181 · see citing works

Shear Stress-Induced Nitric Oxide Release Triggers the Liver Regeneration Cascade

Schoen, J. M., Wang, H. H., Minuk, G. Y., & Lautt, W. W. (2001) · Nitric Oxide · doi:10.1006/niox.2001.0373 · Cited by 170 · see citing works

Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling

Winkler, M., Staniczek, T., Kürschner, S. W., Schmid, C. D., Schönhaber, H., Cordero, J., Kessler, L., Mathes, A., Sticht, C., Neßling, M., et al. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2020.08.033 · Cited by 170 · see citing works

Liver zonation, revisited

Paris, J., & Henderson, N. C. (2022) · Hepatology · doi:10.1002/hep.32408 · Cited by 167 · see citing works

A single cell atlas of the human liver tumor microenvironment

Massalha, H., Halpern, K. B., Abu‐Gazala, S., Jana, T., Massasa, E. E., Moor, A. E., Buchauer, L., Rozenberg, M., Pikarsky, E., Amit, I., et al. (2020) · Molecular Systems Biology · doi:10.15252/msb.20209682 · Cited by 164 · see citing works

Early Hepatic Microvascular Injury in Response to Acetaminophen Toxicity

ITO, Y., BETHEA, N. W., ABRIL, E. R., & MCCUSKEY, R. S. (2003) · Microcirculation · doi:10.1038/sj.mn.7800204 · Cited by 158 · see citing works

Endothelial Notch activation reshapes the angiocrine of sinusoidal endothelia to aggravate liver fibrosis and blunt regeneration in mice

Duan, J., Ruan, B., Yan, X., Liang, L., Song, P., Yang, Z., Liu, Y., Dou, K., Han, H., & Wang, L. (2018) · Hepatology · doi:10.1002/hep.29834 · Cited by 153 · see citing works

The alcohol-inducible form of cytochrome P450 (CYP2E1): Role in toxicology and regulation of expression

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Age‐related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat†

Hilmer, S. N., Cogger, V. C., Fraser, R., McLean, A. J., SULLIVAN, D. R., & Couteur, D. G. L. (2005) · Hepatology · doi:10.1002/hep.20937 · Cited by 149 · see citing works

Hepatic ischemia-reperfusion injury in liver transplant setting: mechanisms and protective strategies

Rampes, S., & Ma, D. (2019) · Journal of Biomedical Research · doi:10.7555/jbr.32.20180087 · Cited by 145 · see citing works

Nitric Oxide and Platelet Aggregation

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Endothelial NO/cGMP/VASP Signaling Attenuates Kupffer Cell Activation and Hepatic Insulin Resistance Induced by High-Fat Feeding

Tateya, S., Rizzo, N. O., Handa, P., Cheng, A. M., Morgan-Stevenson, V., Daum, G., Clowes, A. W., Morton, G. J., Schwartz, M. W., & Kim, F. (2011) · Diabetes · doi:10.2337/db11-0255 · Cited by 138 · see citing works

Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture

Francque, S., Laleman, W., Verbeke, L., Steenkiste, C. V., Casteleyn, C. R., Kwanten, W. J., Dyck, C. V., D'Hondt, M., Ramon, A., Vermeulen, W., et al. (2012) · Laboratory Investigation · doi:10.1038/labinvest.2012.103 · Cited by 136 · see citing works

Clinical Adverse Effects of Endothelin Receptor Antagonists: Insights From the Meta‐Analysis of 4894 Patients From 24 Randomized Double‐Blind Placebo‐Controlled Clinical Trials

Wei, A., Gu, Z., Li, J., Liu, X., Wu, X., Han, Y., & Pu, J. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.116.003896 · Cited by 136 · see citing works

Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis

Furuta, K., Guo, Q., Pavelko, K. D., Lee, J.-H., Robertson, K. D., Nakao, Y., Melek, J., Shah, V. H., Hirsova, P., & Ibrahim, S. H. (2021) · Journal of Clinical Investigation · doi:10.1172/jci143690 · Cited by 136 · see citing works

Protein Acetylation and Acetyl Coenzyme A Metabolism in Budding Yeast

Galdieri, L. C., Zhang, T., Rogerson, D., Lleshi, R., & Vančura, A. (2014) · Eukaryotic Cell · doi:10.1128/ec.00189-14 · Cited by 126 · see citing works

Microvascular rarefaction

Goligorsky, M. S. (2010) · Organogenesis · doi:10.4161/org.6.1.10427 · Cited by 123 · see citing works

Cross-talk between autophagy and KLF2 determines endothelial cell phenotype and microvascular function in acute liver injury

Guixé‐Muntet, S., de Mesquita, F. C., Vila, S., Hernández–Gea, V., Peralta, C., García‐Pagán, J. C., Bosch, J., & Gracia‐Sancho, J. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.07.051 · Cited by 122 · see citing works

Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Liu, M., Cao, S., He, L., Gao, J., Arab, J. P., Cui, H., Xuan, W., Gao, Y., Sehrawat, T. S., Hamdan, F. H., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24843-w · Cited by 120 · see citing works

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

Hu, S., Liu, S., Bian, Y., Poddar, M., Singh, S., Cao, C., McGaughey, J., Bell, A., Blazer, L. L., Adams, J. J., et al. (2022) · Cell Reports Medicine · doi:10.1016/j.xcrm.2022.100754 · Cited by 118 · see citing works

Addition of simvastatin to cold storage solution prevents endothelial dysfunction in explanted rat livers

Russo, L., Gracia‐Sancho, J., García‐Calderó, H., Marrone, G., García‐Pagán, J. C., García‐Cardeña, G., & Bosch, J. (2011) · Hepatology · doi:10.1002/hep.24755 · Cited by 117 · see citing works

Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice

Leibing, T., Géraud, C., Augustin, I., Boutros, M., Augustin, H. G., Okun, J. G., Langhans, C., Zierow, J., Wohlfeil, S. A., Olsavszky, V., et al. (2018) · Hepatology · doi:10.1002/hep.29613 · Cited by 116 · see citing works

Cirrhotic portal hypertension: From pathophysiology to novel therapeutics

Gunarathne, L. S., Rajapaksha, H., Shackel, N. A., Angus, P., & Herath, C. B. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i40.6111 · Cited by 116 · see citing works

A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver

Inverso, D., Shi, J., Lee, K. H., Jakab, M., Ben-Moshe, S., Kulkarni, S. R., Schneider, M., Wang, G., Komeili, M., Vélez, P. A., et al. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.05.001 · Cited by 114 · see citing works

Hepatic stellate cell–derived platelet‐derived growth factor receptor‐alpha‐enriched extracellular vesicles promote liver fibrosis in mice through SHP2

Kostallari, E., Hirsova, P., Prasnicka, A., Verma, V. K., Yaqoob, U., Wongjarupong, N., Roberts, L. R., & Shah, V. H. (2018) · Hepatology · doi:10.1002/hep.29803 · Cited by 111 · see citing works

Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity

Bondareva, O., Rodríguez‐Aguilera, J. R., de Oliveira, F. S., Liao, L., Rose, A., Gupta, A., Singh, K., Geier, F. M., Schuster, J., Boeckel, J., et al. (2022) · Nature Metabolism · doi:10.1038/s42255-022-00674-x · Cited by 111 · see citing works

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