Cited by 2,137Acute Ischemic Stroke ManagementCardiovascular Health and Risk FactorsGlobal Health and Epidemiology

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Global Burden of Stroke

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Katan, Mira, Luft, Andreas·2018·Seminars in Neurology

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Abstract

Stroke is the second leading cause of death and a major cause of disability worldwide. Its incidence is increasing because the population ages. In addition, more young people are affected by stroke in low- and middle-income countries. Ischemic stroke is more frequent but hemorrhagic stroke is responsible for more deaths and disability-adjusted life-years lost. Incidence and mortality of stroke differ between countries, geographical regions, and ethnic groups. In high-income countries mainly, improvements in prevention, acute treatment, and neurorehabilitation have led to a substantial decrease in the burden of stroke over the past 30 years. This article reviews the epidemiological and clinical data concerning stroke incidence and burden around the globe.

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Magnetic Field Driven Ceria Nanosystems for Mitochondria Targeted Therapy of Ischemic Stroke
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“Stroke, particularly acute ischemic stroke (AIS), continues to be a major contributor to morbidity and mortality globally, placing a substantial burden on healthcare systems [1].”
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“Ischemic stroke is one of the main diseases with high mortality and disability worldwide [1].”
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“About 85% of the stroke cases reported are classified as ischemic stroke, a focal neurological deficit that occurs due to insufficient cerebral blood flow (CBF) triggered by occlusion of blood vessel [1].”
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Corlăteanu, A., Stratan, I., Covanţev, S., Botnaru, V., Corlateanu, O., & Siafakas, N. M. (2021) · Asthma Research and Practice · doi:10.1186/s40733-021-00069-x · Cited by 38
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“Ischemic stroke accounts for the majority of strokes, yet hemorrhagic stroke is responsible for more deaths and DALYs lost (15).”
Background
Bioactive Flavonoids Icaritin and Icariin Protect against Cerebral Ischemia–Reperfusion-Associated Apoptosis and Extracellular Matrix Accumulation in an Ischemic Stroke Mouse Model
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Role and Impact of Cerebrolysin for Ischemic Stroke Care
Muresanu, D. F., Popa, L. L., Chira, D., Dăbală, V., Hapca, E., Vlad, I. M., Văcăraș, V., Popescu, B. O., Cherecheș, R. M., Strilciuc, Ș., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051273 · Cited by 36
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HDAC1 is Involved in Neuroinflammation and Blood-Brain Barrier Damage in Stroke Pathogenesis
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Hybrid Brain-Computer Interface Controlled Soft Robotic Glove for Stroke Rehabilitation
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VX‐765 enhances autophagy of human umbilical cord mesenchymal stem cells against stroke‐induced apoptosis and inflammatory responses via AMPK/mTOR signaling pathway
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Unmet Needs for Rehabilitative Management in Common Health-Related Problems Negatively Impact the Quality of Life of Community-Dwelling Stroke Survivors
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Stroke and Emerging Blood Biomarkers: A Clinical Prospective
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Authors: Katan, M., & Luft, A.
Affiliations: Department of Neurology, Stroke Center, University Hospital of Zurich, Zurich, Switzerland
University Hospital Zurich (CH)
Corresponding author: Luft, Andreas
ORCID: Luft, Andreas
Venue: Seminars in Neurology
Publisher: Georg Thieme Verlag KG
Published: 2018-04
Volume: 38
Issue: 02
Pages: 208-211
ISSN: 0271-8235 (ISSN-L)
1098-9021
DOI: 10.1055/s-0038-1649503
OpenAlex: W2803306216
Cited by: 2,137
References: 57
Citations by year: 2026: 164 · 2025: 350 · 2024: 361 · 2023: 387 · 2022: 376 · 2021: 276 · 2020: 159 · 2019: 55 · 2018: 7
FWCI: 17.75
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Seminars in Neurology (publishedVersion)
PubMed (publishedVersion)
Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
Zurich Open Repository and Archive (University of Zurich)
Topics: Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
Keywords: stroke, global burden of disease, stroke incidence, stroke mortality, ischemic stroke, hemorrhagic stroke, disability-adjusted life years, population aging, young adults, low- and middle-income countries, ethnic disparities, stroke prevention, neurorehabilitation
MeSH terms: Humans, Sex Factors, Global Health, Disease Management, Stroke

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